Murielle Lombard

Chargée de recherche CNRS
29
Documents

Publications

Publications

Image document

Functional redundancy in tRNA dihydrouridylation

Claudia Sudol , Lea-Marie Kilz , V. Marchand , Quentin Thullier , Vincent Guérineau et al.
Nucleic Acids Research, 2024, 52 (10), pp.5880-5894. ⟨10.1093/nar/gkae325⟩
Article dans une revue hal-04614743 v1
Image document

An organic O donor for biological hydroxylation reactions

Katayoun Kazemzadeh Ferizhendi , Philippe Simon , Ludovic Pelosi , Emmanuel Séchet , Roache Arulanandam et al.
Proceedings of the National Academy of Sciences of the United States of America, 2024, 121 (13), pp.e2321242121. ⟨10.1073/pnas.2321242121⟩
Article dans une revue pasteur-04665824 v1
Image document

Activation of Coq6p, a FAD Monooxygenase Involved in Coenzyme Q Biosynthesis, by Adrenodoxin Reductase/Ferredoxin

Lucie Gonzalez , Samuel Chau-Duy Tam Vo , Bruno Faivre , Fabien Pierrel , Marc Fontecave et al.
ChemBioChem, 2024, 25 (5), ⟨10.1002/cbic.202300738⟩
Article dans une revue hal-04728040 v1
Image document

Evolutionary Diversity of Dus2 Enzymes Reveals Novel Structural and Functional Features among Members of the RNA Dihydrouridine Synthases Family

Murielle Lombard , Colbie J Reed , Ludovic Pecqueur , Bruno Faivre , Sabrine Toubdji et al.
Biomolecules, 2022, 12 (12), pp.1760. ⟨10.3390/biom12121760⟩
Article dans une revue hal-04238858 v1
Image document

Dihydrouridine in the transcriptome: New life for this ancient RNA chemical modification

Damien Brégeon , Ludovic Pecqueur , Sabrine Toubdji , Claudia Sudol , Murielle Lombard et al.
ACS Chemical Biology, 2022, 17 (7), pp.1638-1657. ⟨10.1021/acschembio.2c00307⟩
Article dans une revue hal-03836746 v1
Image document

Ultrafast Dynamics of Fully Reduced Flavin in Catalytic Structures of Thymidylate Synthase ThyX

Nadia Dozova , Fabien Lacombat , Murielle Lombard , Djemel Hamdane , Pascal Plaza
Physical Chemistry Chemical Physics, 2021, 23, pp.22692-22702. ⟨10.1039/D1CP03379D⟩
Article dans une revue hal-03361405 v1
Image document

Dihydrouridine synthesis in tRNAs is under reductive evolution in Mollicutes

Bruno Faivre , Murielle Lombard , Soufyan Fakroun , Chau-Duy-Tam Vo , Catherine Goyenvalle et al.
RNA Biology, 2021, 18 (12), pp.2278 - 2289. ⟨10.1080/15476286.2021.1899653⟩
Article dans une revue hal-03837152 v1
Image document

An enzymatic activation of formaldehyde for nucleotide methylation

Charles Bou-Nader , Frederick W Stull , Ludovic Pecqueur , Philippe Simon , Vincent Guérineau et al.
Nature Communications, 2021, 12, pp.4542. ⟨10.1038/s41467-021-24756-8⟩
Article dans une revue hal-03343627 v1
Image document

The O2-independent pathway of ubiquinone biosynthesis is essential for denitrification in Pseudomonas aeruginosa

Chau-Duy-Tam Vo , Julie Michaud , Sylvie Elsen , Bruno Faivre , Emmanuelle Bouveret et al.
Journal of Biological Chemistry, 2020, 295 (27), pp.9021-9032. ⟨10.1074/jbc.RA120.013748⟩
Article dans une revue pasteur-02746713 v1
Image document

Ubiquinone Biosynthesis over the Entire O2 Range: Characterization of a Conserved O2-Independent Pathway

Ludovic Pelosi , Chau-Duy-Tam Vo , Sophie Saphia Abby , Laurent Loiseau , Bérengère Rascalou et al.
mBio, 2019, 10 (4), ⟨10.1128/mBio.01319-19⟩
Article dans une revue hal-02183791 v1

Structural and Functional Characterization of 4‐Hydroxyphenylacetate 3‐Hydroxylase from Escherichia coli

Yifan Deng , Bruno Faivre , Olivier Back , Murielle Lombard , Ludovic Pecqueur et al.
ChemBioChem, 2019, 10 (4), ⟨10.1002/cbic.201900277⟩
Article dans une revue hal-02359262 v1
Image document

A Soluble Metabolon Synthesizes the Isoprenoid Lipid Ubiquinone

Mahmoud Hajj Chehade , Ludovic Pelosi , Cameron David Fyfe , Laurent Loiseau , Bérengère Rascalou et al.
Cell Chemical Biology, 2019, 26 (4), pp.482-492.e7. ⟨10.1016/j.chembiol.2018.12.001⟩
Article dans une revue hal-02071798 v1
Image document

Flavin-dependent epitranscriptomic world

Murielle Lombard , Djemel Hamdane
Archives of Biochemistry and Biophysics, 2017, ⟨10.1016/j.abb.2017.06.011⟩
Article dans une revue hal-01542856 v1

Power of protein/tRNA functional assembly against aberrant aggregation

Charles Bou-Nader , Ludovic Pecqueur , David Cornu , Murielle Lombard , Manuela Dezi et al.
Physical Chemistry Chemical Physics, 2017, ⟨10.1039/c7cp05599d⟩
Article dans une revue hal-02187768 v1

The UbiK protein is an accessory factor necessary for bacterial ubiquinone (UQ) biosynthesis and forms a complex with the UQ biogenesis factor UbiJ

Laurent Loiseau , Cameron Fyfe , Laurent Aussel , Mahmoud Hajj Chehade , Sara B. Hernández et al.
Journal of Biological Chemistry, 2017, 292 (28), pp.11937 - 11950. ⟨10.1074/jbc.M117.789164⟩
Article dans une revue hal-01615493 v1
Image document

Coenzyme Q Biosynthesis: Evidence for a Substrate Access Channel in the FAD-Dependent Monooxygenase Coq6

Alexandre Ismail , Vincent Leroux , Myriam Smadja , Lucie Gonzalez , Murielle Lombard et al.
PLoS Computational Biology, 2016, 12 (1), pp.e1004690. ⟨10.1371/journal.pcbi.1004690⟩
Article dans une revue hal-01424489 v1

A chemical chaperone induces inhomogeneous conformational changes in flexible proteins

Djemel Hamdane , Christophe Velours , David Cornu , Magali Nicaise , Murielle Lombard et al.
Physical Chemistry Chemical Physics, 2016, 18 (30), pp.20410--20421. ⟨10.1039/c6cp03635j⟩
Article dans une revue hal-02393836 v1

Expression in yeast, new substrates, and construction of a first 3D model of human orphan cytochrome P450 2U1: Interpretation of substrate hydroxylation regioselectivity from docking studies.

Lionel Ducassou , Gabriella Jonasson , Laura Dhers , Nicolas Pietrancosta , Booma Ramassamy et al.
BBA - Biochimica et Biophysica Acta, 2015, 1850 (7), pp.1426-37. ⟨10.1016/j.bbagen.2015.03.014⟩
Article dans une revue hal-01449701 v1
Image document

Biosynthesis and physiology of coenzyme Q in bacteria.

Laurent Aussel , Fabien Pierrel , Laurent Loiseau , Murielle Lombard , Marc Fontecave et al.
Biochimica biophysica acta (BBA) - Bioenergetics, 2014, 1837 (7), pp.1004-1011. ⟨10.1016/j.bbabio.2014.01.015⟩
Article dans une revue hal-01077983 v1
Image document

A new gene involved in coenzyme Q biosynthesis in Escherichia coli: UbiI functions in aerobic C5-hydroxylation

Mahmoud Hajj Chehade , Laurent Loiseau , Murielle Lombard , Ludovic Pecqueur , Alexandre Ismail et al.
Journal of Biological Chemistry, 2013, 288 (27), pp.20085-92. ⟨10.1074/jbc.M113.480368⟩
Article dans une revue hal-00904907 v1
Image document

Intermolecular electron transfer in two-iron superoxide reductase: a putative role for the desulforedoxin center as an electron donor to the iron active site.

Florence Bonnot , Simon Duval , Murielle Lombard , Julien Valton , Chantal Houée-Levin et al.
Journal of Biological Inorganic Chemistry, 2011, 16 (6), pp.889-98. ⟨10.1007/s00775-011-0788-5⟩
Article dans une revue hal-01075287 v1
Image document

Superoxide reductase from Desulfoarculus baarsii: identification of protonation steps in the enzymatic mechanism.

Vincent Nivière , Marcel Asso , Claire O Weill , Murielle Lombard , Bruno Guigliarelli et al.
Biochemistry, 2004, 43, pp.808-18. ⟨10.1021/bi035698i⟩
Article dans une revue hal-01075794 v1
Image document

Identification of iron(III) peroxo species in the active site of the superoxide reductase SOR from Desulfoarculus baarsii.

Christelle Mathé , Tony A Mattioli , Olivier Horner , Murielle Lombard , Jean-Marc Latour et al.
Journal of the American Chemical Society, 2002, pp.4966-7
Article dans une revue hal-01075797 v1
Image document

Pulse radiolysis studies on superoxide reductase from Treponema pallidum.

V Nivière , M Lombard , M. Fontecave , C Houée-Levin
FEBS Letters, 2001, 497, pp.171-3. ⟨10.1016/S0014-5793(01)02468-1⟩
Article dans une revue hal-01075800 v1
Image document

Superoxide reductase from Desulfoarculus baarsii: reaction mechanism and role of glutamate 47 and lysine 48 in catalysis.

M Lombard , C Houée-Levin , D Touati , M. Fontecave , V Nivière
Biochemistry, 2001, pp.5032-40
Article dans une revue hal-01075802 v1
Image document

Superoxide reductase from Desulfoarculus baarsii.

Vincent Nivière , Murielle Lombard
Methods in Enzymology, 2001, 349, pp.123-9
Article dans une revue hal-01075799 v1
Image document

Reaction of the desulfoferrodoxin from Desulfoarculus baarsii with superoxide anion. Evidence for a superoxide reductase activity.

M Lombard , M. Fontecave , D Touati , V Nivière
Journal of Biological Chemistry, 2000, 275, pp.115-21. ⟨10.1074/jbc.275.1.115⟩
Article dans une revue hal-01075803 v1
Image document

Superoxide reductase as a unique defense system against superoxide stress in the microaerophile Treponema pallidum.

M Lombard , D Touati , M. Fontecave , V Nivière
Journal of Biological Chemistry, 2000, 275 (35), pp.27021-6
Article dans une revue hal-01075805 v1

Anaerobic ubiquinone biosynthetic pathway in Escherichia coli

Katayoun Kazemzadeh , Sophie Abby , Sophie-Carole Chobert , Mahmoud Hajj Chehade , M Lombard et al.
Société française de biochimie et biologie moléculaire, Jul 2022, Paris, France
Communication dans un congrès hal-04976976 v1