Nicolas Degauque
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Affiliations actuelles
- Centre de Recherche en Transplantation et Immunologie - Center for Research in Transplantation and Translational Immunology (U1064 Inserm - CR2TI)
- Team 4 : Deciphering organ immune regulation in inflammation and transplantation (DORI-t) (Team 4 - U1064 Inserm - CR2TI)
Identifiants chercheurs
Présentation
I am an INSERM Research Scientist (CR1) that will co-lead in 2028 Team 4 at CR2TI (UMR1064, Nantes Université), working at the intersection of mechanistic immunology and clinical transplantation. My research focuses on immune-mediated kidney injury — particularly antibody-mediated rejection and ANCA-associated vasculitis — with a central interest in the roles of CD8⁺ T-cell subsets. I combine functional human in vitro models, large well-phenotyped cohorts, and high-dimensional immune profiling (spectral flow cytometry, Hyperion multiplex imaging) to identify biomarkers and therapeutic targets for long-term graft protection.
Domaines de recherche
Immunologie
Urologie et Néphrologie
Compétences
Spatial imaging
Cytometry
Cellular immunology
Publications
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