Nicolas MACIAN

29
Documents

Publications

Publications

Bioavailable human metabolites from TOTUM-448 (plant-based formulation) maintain liver cell functionality in a hyperlipidic context that drives MASLD onset

Fabien Wauquier , Vivien Chavanelle , Annie Bouchard-Mercier , Line Boutin-Wittrant , Yolanda Otero et al.
Scientific Reports, 2025, ⟨10.1038/s41598-025-32556-z⟩
Article dans une revue hal-05462850 v1

Systematic review and co‐ordinate based meta‐analysis to summarize the utilization of functional brain imaging in conjunction with human models of peripheral and central sensitization

Sophie Clarke , Richard Rogers , Vishvarani Wanigasekera , Francesca Fardo , Hossein Pia et al.
European Journal of Pain, 2024, 28 (7), pp.1069-1094. ⟨10.1002/ejp.2251⟩
Article dans une revue hal-04943626 v1

Neuropathic Component Characteristics in Chronic Secondary Musculoskeletal Pain After Postmenopausal Osteoporotic Fractures: A Pilot Cross‐Sectional Study

Marie-Eva Pickering , Serge Perrot , Dualé Christian , Véronique Morel , Nicolas Macian et al.
Pain Research and Management, 2024, 2024 (1), ⟨10.1155/prm/9766698⟩
Article dans une revue (article de synthèse) hal-05458321 v1
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Reduced Production of Pro-Inflammatory and Pro-Catabolic Factors by Human Serum Metabolites Derived from a Patented Saffron Extract Intake

Line Pourtau , Fabien Wauquier , Line Boutin-Wittrant , David Gaudout , Benjamin Moras et al.
Pharmaceutics, 2024, 16, ⟨10.3390/pharmaceutics16030336⟩
Article dans une revue hal-04643323 v1

Génétique de la douleur chronique

Christian Dualé , Pierre Blanc , Nicolas Macian
Douleur et Analgésie, 2023, 36 (4), pp.234-49. ⟨10.3166/dea-2022-0275⟩
Article dans une revue hal-04741824 v1

Assessing brain function in stressed healthy individuals following the use of a combination of green tea, Rhodiola, magnesium, and B vitamins: an fMRI study

Gisèle Pickering , Lionel Noah , Bruno Pereira , Jonathan Goubayon , Vincent Leray et al.
Frontiers in Nutrition, 2023, 10, pp.1-15. ⟨10.3389/fnut.2023.1211321⟩
Article dans une revue hal-04441458 v1

Common miRNAs of Osteoporosis and Fibromyalgia: A Review

Soline Philippe , Marine Delay , Nicolas Macian , Véronique Morel , Marie-Eva Pickering
International Journal of Molecular Sciences, 2023, 24 (17), pp.13513. ⟨10.3390/ijms241713513⟩
Article dans une revue hal-04719274 v1
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Circulating Human Metabolites Resulting from TOTUM-070 Absorption (a Plant-Based, Polyphenol-Rich Ingredient) Improve Lipid Metabolism in Human Hepatocytes: Lessons from an Original Ex Vivo Clinical Trial

Fabien Wauquier , Line Boutin-Wittrant , Stéphanie Krisa , Josep Valls , Cedric Langhi et al.
Nutrients, 2023, 15 (8), pp.1903. ⟨10.3390/nu15081903⟩
Article dans une revue hal-04198979 v1

Circulating bioactives resulting from totum-854 absorption in humans protects primary human endothelial cells against lipotoxicity: lessons from an original ex vivo clinical trial

Fabien Wauquier , Doriane Ripoche , Line Boutin-Wittrant , Yolanda F Otero , Florian Le Joubioux et al.
Journal of Hypertension -Supplement-, 2023, 41, pp.E308-E308
Article dans une revue hal-04323875 v1
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Short-Term Magnesium Therapy Alleviates Moderate Stress in Patients with Fibromyalgia: A Randomized Double-Blind Clinical Trial

Nicolas Macian , Christian Dualé , Marion Voute , Vincent Leray , Marion Courrent et al.
Nutrients, 2022, 14 (10), pp.2088. ⟨10.3390/nu14102088⟩
Article dans une revue hal-04256395 v1

Effect of a Combination of Magnesium, B Vitamins, Rhodiola, and Green Tea (L-Theanine) on Chronically Stressed Healthy Individuals—A Randomized, Placebo-Controlled Study

Lionel Noah , Veronique Morel , Claire Bertin , Etienne Pouteau , Nicolas Macian et al.
Nutrients, 2022, 14 (9), pp.1863. ⟨10.3390/nu14091863⟩
Article dans une revue hal-04256366 v1
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Benefits of Circulating Human Metabolites from Fish Cartilage Hydrolysate on Primary Human Dermal Fibroblasts, an Ex Vivo Clinical Investigation for Skin Health Applications

Fabien Wauquier , Line Boutin-Wittrant , Elodie Bouvret , Julie Le Faouder , Véronique Roux et al.
Nutrients, 2022, 14 (23), pp.5027. ⟨10.3390/nu14235027⟩
Article dans une revue hal-04000218 v1
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Circulating Human Serum Metabolites Derived from the Intake of a Saffron Extract (Safr’InsideTM) Protect Neurons from Oxidative Stress: Consideration for Depressive Disorders

Fabien Wauquier , Line Boutin-Wittrant , Line Pourtau , David Gaudout , Benjamin Moras et al.
Nutrients, 2022, 14 (7), pp.1511. ⟨10.3390/nu14071511⟩
Article dans une revue hal-03658538 v1

The Added Value of Sensitivity to Nonnoxious Stimuli to Predict an Individual's Sensitivity to Pain.

Christian Dualé , Vincent Leray , Fatiha Giron , Sylvia Boulliau , Nicolas Macian et al.
Pain Physician, 2021, 24 (6), pp.E783-E794
Article dans une revue hal-04741735 v1

Magnesium for Pain Treatment in 2021? State of the Art

Véronique Morel , Marie-Eva Pickering , Jonathan Goubayon , Marguérite Djobo , Nicolas Macian et al.
Nutrients, 2021, 13 (5), pp.1397. ⟨10.3390/nu13051397⟩
Article dans une revue hal-04256664 v1
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Evaluating the role of orange juice, HESPERidin in vascular HEALTH benefits (HESPER-HEALTH study): protocol for a randomised controlled trial

Marie-Anne Verny , Dragan Milenkovic , Nicolas Macian , Bruno Pereira , Rémy Evrard et al.
BMJ Open, 2021, 11 (11), pp.e053321. ⟨10.1136/bmjopen-2021-053321⟩
Article dans une revue hal-03462748 v1
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Electrochemical Skin Conductance and Quantitative Sensory Testing on Fibromyalgia

Gisèle Pickering , Alexanne Achard , Alexandrine Corriger , Sophia Sickout‐arondo , Nicolas Macian et al.
Pain Practice, 2020, 20 (4), pp.348-356. ⟨10.1111/papr.12857⟩
Article dans une revue hal-02935679 v1

Non‐specific analgesia during a clinical trial in fibromyalgia

Christian Dualé , Nicolas Macian , Fatiha Giron , Gisèle Pickering
European Journal of Clinical Investigation, 2020, 50 (11), ⟨10.1111/eci.13337⟩
Article dans une revue hal-04741743 v1

Hormonal status and cognitivo‐emotional profile in real‐life neuropathic pain patients: a case control study

Alexandrine Corriger , Martine Duclos , Jean-Benoît Corcuff , Céline Lambert , Geoffroy Marceau et al.
Pain Practice, 2019, 19 (7), ⟨10.1111/papr.12800⟩
Article dans une revue hal-02193914 v1

N-acetylcysteine prevents glutathione decrease and does not interfere with paracetamol antinociceptive effect at therapeutic dosage: a randomized double-blind controlled trial in healthy subjects

G. Pickering , N. Macian , Isabelle Papet , C. Dualé , C. Coudert et al.
Fundamental & Clinical Pharmacology, 2019, 33 (3), pp.303-311. ⟨10.1111/fcp.12437⟩
Article dans une revue hal-01938702 v1

Effectiveness and safety of 5% lidocaine-medicated plaster on localized neuropathic pain after knee surgery

Gisèle Pickering , Marion Voute , Nicolas Macian , Hervé Ganry , Bruno Pereira
Pain, 2019, 160 (5), pp.1186-1195. ⟨10.1097/j.pain.0000000000001502⟩
Article dans une revue hal-02325181 v1

Paracetamol and Pain Modulation by TRPV1, UGT2B15, SULT1A1 Genotypes: A Randomized Clinical Trial in Healthy Volunteers

Gisèle Pickering , Isabelle Creveaux , Nicolas Macian , Bruno Pereira
Pain Medicine, 2019, ⟨10.1093/pm/pnz037⟩
Article dans une revue hal-02325093 v1
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Milnacipran poorly modulates pain in patients suffering from fibromyalgia: a randomized double-blind controlled study

Gisèle Pickering , Nicolas Macian , Noémie Delage , Pascale Picard , Jean-Michel Cardot et al.
Drug Design, Development and Therapy, 2018, 12, pp.2485-2496. ⟨10.2147/DDDT.S162810⟩
Article dans une revue hal-01870569 v1

Reliability Study in Five Languages of the Translation of the Pain Observational Scale Algoplus

Gisèle Pickering , Fiammetta Monacelli , Juan Manuel Pérez-Castejón Garrote , Hirondina Guarda , Luis Batalha et al.
Pain Medicine, 2017, ⟨10.1093/pm/pnw356⟩
Article dans une revue hal-01662587 v1
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The brain signature of paracetamol in healthy volunteers: a double-blind randomized trial

Gisèle Pickering , Adrian Kastler , Nicolas Macian , Bruno Pereira , Romain Valabregue et al.
Drug Design, Development and Therapy, 2015, 9, pp.3853-3862. ⟨10.2147/DDDT.S81004⟩
Article dans une revue hal-01214449 v1
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Phase I clinical trial to evaluate TOTUM-63, a botanical complex for managing prediabetes

P. Sirvent , M. Bargetto , V. Chavanelle , Nicolas Macian , Sylvia Boulliau et al.
77th Scientific Sessions of American Diabetes Association, Jun 2017, San Diego, United States
Poster de conférence hal-01682304 v1