Nicolas Spinelli

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Publications

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Nicolas Spinelli , Isabelle Baussanne
31th SCT Young Research Fellows Meeting, Feb 2024, La Tronche, Faculté de Médecine et Pharmacie, Grenoble, France
Poster de conférence hal-04794992 v1

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Nicolas Spinelli , Isabelle Baussanne
3ème Journée du GDR ChemBio, Jun 2023, Illkirch, Strasbourg, France
Poster de conférence hal-04794962 v1

Analytical methods for the detection of pollutants in water

Imen Kazane , Karine Gorgy , Chantal Gondran , Nicolas Spinelli , Ali Zazaoua et al.
The second international Workshop on Chemical Engineering (IWCE23), Dec 2023, Setif, Algeria
Poster de conférence hal-04909633 v1

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Nicolas Spinelli , Isabelle Baussanne
UGA EDCSV PhD Day 2023, Sep 2023, Grenoble, France
Poster de conférence hal-04795049 v1

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Nicolas Spinelli , Isabelle Baussanne
Journée de Printemps SCF section Rhône-Alpes, Jun 2022, Le Bourget du lac - Chambery, France
Poster de conférence hal-04795022 v1

Constrained oligonucleotides based chiral catalyst

Yoann Colas , Stéphane Ménage , Caroline Marchi- Delapierre , Nicolas Spinelli
FrenchBIC annual Meeting, Oct 2020, online, France
Poster de conférence hal-05052724 v1

Constrained oligonucleotides based chiral catalyst

Yoann Colas , Stéphane Ménage , Caroline Marchi- Delapierre , Nicolas Spinelli
2nd FrenchBIC summer school on methods for studying metals in biology (METBIO), Oct 2019, Carry-le-Rouet et Marseille, France
Poster de conférence hal-05052709 v1
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Aptasensors based on silicon nanowire field-effect transistors for electrical detection of thrombin

Rony Midahuen , Valerie Stambouli , Caroline Fontelaye , Guillaume Nonglaton , Nicolas Spinelli et al.
Microelectronic Engineering, 2024, 286, pp.112130. ⟨10.1016/j.mee.2023.112130⟩
Article dans une revue cea-04778501 v1
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Use of Constrained G-Quadruplexes for Enantioselective Sulfoxidation Site Mapping

Yoann Colas , Stéphane Ménage , Caroline Marchi- Delapierre , Nicolas Spinelli
ChemCatChem, 2024, 16 (1), pp.e202300914. ⟨10.1002/cctc.202300914⟩
Article dans une revue hal-04246624 v1
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Aptamer conjugated Si nanowire network/poly(pyrrole)-NTA structure for electrochemical sensing

Monica Vallejo-Perez , Essohanam Beke , Chantal Gondran , Karine Gorgy , Isabelle Gélard et al.
Sensing and Bio-Sensing Research, 2023, 42, pp.100593. ⟨10.1016/j.sbsr.2023.100593⟩
Article dans une revue hal-04272147 v1
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Conformational transition in SPR experiments: impact of spacer length, immobilization mode and aptamer density on signal sign and amplitude

Marina Pons , Marine Perenon , Hugues Bonnet , Emilie Gillon , Celio Vallée et al.
Analyst, 2022, 19 (147), pp.4197-4205. ⟨10.1039/D2AN00824F⟩
Article dans une revue hal-03813142 v1

Negative SPR Signals during Low Molecular Weight Analyte Recognition

H. Bonnet , L. Coche-Guérente , E. Defrancq , N. Spinelli , A. van Der Heyden et al.
Analytical Chemistry, 2021, 93 (8), pp.4134-4140. ⟨10.1021/acs.analchem.1c00071⟩
Article dans une revue hal-03177913 v1
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Recent progress in the design of G-quadruplex–based electrochemical aptasensors

Jérôme Dejeu , Angéline van Der Heyden , Nicolas Spinelli , Eric Defrancq , Liliane Coche-Guérente
Current Opinion in Electrochemistry, 2021, 30, pp.100812. ⟨10.1016/j.coelec.2021.100812⟩
Article dans une revue hal-03338912 v1
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Optimization of GOPS-Based Functionalization Process and Impact of Aptamer Grafting on the Si Nanonet FET Electrical Properties as First Steps towards Thrombin Electrical Detection

Monica Vallejo-Perez , Céline Ternon , Nicolas Spinelli , Fanny Morisot , Christoforos Theodorou et al.
Nanomaterials, 2020, 10 (9), pp.1842. ⟨10.3390/nano10091842⟩
Article dans une revue hal-02978359 v1
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Direct Detection of Low Molecular Weight Compounds in 2D and 3D Aptasensors by Biolayer Interferometry

Anthony Vignon , Arthur Flaget , Maxime Michelas , Mehdi Deghdir , Éric Defrancq et al.
ACS Sensors, 2020, 5 (8), pp.2326-2330. ⟨10.1021/acssensors.0c00925⟩
Article dans une revue hal-02917003 v1

Influence of Aptamer Surface Coverage on Small Target Recognition: A SPR and QCM-D Comparative Study

Hannah Macdonald , Hugues Bonnet , Angéline van der Heyden , Eric Defrancq , Nicolas Spinelli et al.
Journal of Physical Chemistry C, 2019, 123 (22), pp.13561-13568. ⟨10.1021/acs.jpcc.9b00845⟩
Article dans une revue hal-04405856 v1
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Influence of Aptamer Surface Coverage on Small Target Recognition: A SPR and QCM-D Comparative Study

Hannah Macdonald , Hugues Bonnet , Angéline van Der Heyden , Eric Defrancq , Nicolas Spinelli et al.
Journal of Physical Chemistry C, 2019, 123 (22), pp.13561-13568. ⟨10.1021/acs.jpcc.9b00845⟩
Article dans une revue hal-02180487 v1
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Impact of Conformational Transitions on SPR Signals—Theoretical Treatment and Application in Small Analytes/Aptamer Recognition

Jérôme Dejeu , Hugues Bonnet , Nicolas Spinelli , Eric Defrancq , Liliane Coche-Guerente et al.
Journal of Physical Chemistry C, 2018, 122 (37), pp.21521-21530. ⟨10.1021/acs.jpcc.8b07298⟩
Article dans une revue hal-02180482 v1

Impact of Conformational Transitions on SPR Signals—Theoretical Treatment and Application in Small Analytes/Aptamer Recognition

Jérôme Dejeu , Hugues Bonnet , Nicolas Spinelli , Eric Defrancq , Liliane Coche-Guérente et al.
Journal of Physical Chemistry C, 2018, 122 (37), pp.21521-21530. ⟨10.1021/acs.jpcc.8b07298⟩
Article dans une revue hal-04405867 v1

The pKa value of the proximal water molecule trans to a high-valent MnV=O porphyrin: Towards the control of reactivity by pH

Laurie Saint-Germes , Laure Bar , Jérôme Dejeu , Nicolas Spinelli , Eric Defrancq et al.
Dalton Transactions, 2017, 46 (36), pp.12088-12094. ⟨10.1039/C7DT01829K⟩
Article dans une revue hal-01649404 v1

Highly Sensitive Bisphenol-A Electrochemical Aptasensor Based on Poly(Pyrrole-Nitrilotriacetic Acid)-Aptamer Film

Imen Kazane , Karine Gorgy , Chantal Gondran , Nicolas Spinelli , Ali Zazoua et al.
Analytical Chemistry, 2016, 88 (14), pp.7268 - 7273. ⟨10.1021/acs.analchem.6b01574⟩
Article dans une revue hal-01644665 v1

A label-free photoelectrochemical cocaine aptasensor based on an electropolymerized ruthenium-intercalator complex

Fatima Haddache , Alan Le Goff , Nicolas Spinelli , Priyanka Gairola , Karine Gorgy et al.
Electrochimica Acta, 2016, 219, pp.82 - 87. ⟨10.1016/j.electacta.2016.09.127⟩
Article dans une revue hal-01644537 v1

Prefolded Synthetic G-Quartets Display Enhanced Bioinspired Properties

Theodore Flack , Thibaut Constantin , Sylvain Penasse , Jérôme Dejeu , Béatrice Gennaro et al.
Chemistry - A European Journal, 2016, 22 (5), pp.1760 - 1767. ⟨10.1002/chem.201504572⟩
Article dans une revue istex hal-01400347 v1

Sensor Based on Aptamer Folding to Detect Low-Molecular Weight Analytes

Alina Osypova , Dhruv Thakar , Jérôme Dejeu , Hugues Bonnet , Angéline van Der Heyden et al.
Analytical Chemistry, 2015, 87 (15), pp.7566 - 7574. ⟨10.1021/acs.analchem.5b01736⟩
Article dans une revue hal-01651120 v1

Construction of anti-parallel G-quadruplexes through sequential templated click

Romaric Bonnet , Thomas Lavergne , Béatrice Gennaro , Nicolas Spinelli , Eric Defrancq
Chemical Communications, 2015, 51 (23), pp.4850-4853. ⟨10.1039/C4CC09744K⟩
Article dans une revue hal-02178767 v1

Macrocyclic Host-Dye Reporter for Sensitive Sandwich-Type Fluorescent Aptamer Sensor

Cheng Yang , Nicolas Spinelli , Sandrine Perrier , Eric Defrancq , Eric Peyrin
Analytical Chemistry, 2015, 87 (6), pp.3139 - 3143. ⟨10.1021/acs.analchem.5b00341⟩
Article dans une revue hal-01651412 v1

A multi-ligation strategy for the synthesis of heterofunctionalized glycosylated scaffolds

Baptiste Thomas , Michele Fiore , Gour Chand Daskhan , Nicolas Spinelli , Olivier Renaudet
Chemical Communications, 2015, 51 (25), pp.5436 - 5439. ⟨10.1039/c4cc05451b⟩
Article dans une revue hal-01650732 v1

Label-Free Photoelectrochemical Detection of Double-Stranded HIV DNA by Means of a Metallointercalator-Functionalized Electrogenerated Polymer

Fatima Haddache , Alan Le goff , Bertrand Reuillard , Karine Gorgy , Chantal Gondran et al.
Chemistry - A European Journal, 2014, 20 (47), pp.15555 - 15560. ⟨10.1002/chem.201404335⟩
Article dans une revue istex hal-01652231 v1

Surface-immobilized DNAzyme-type biocatalysis

Loïc Stefan , Thomas Lavergne , Nicolas Spinelli , Eric Defrancq , David Monchaud
Nanoscale, 2014, 6 (5), ⟨10.1039/c3nr05954e⟩
Article dans une revue hal-01652423 v1

Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications

Nicolas Spinelli , Eric Defrancq , François Morvan
Chemical Society Reviews, 2013, 42, pp.4557-4573. ⟨10.1039/c2cs35406c⟩
Article dans une revue hal-00822875 v1

Label-free impedimetric thrombin sensor based on poly(pyrrole-nitrilotriacetic acid)-aptamer film

Hui Xu , Karine Gorgy , Chantal Gondran , Alan Le Goff , Nicolas Spinelli et al.
Biosensors and Bioelectronics, 2013, 41, pp.90 - 95. ⟨10.1016/j.bios.2012.07.044⟩
Article dans une revue istex hal-01652825 v1

Synthesis and characterization of oligonucleotide conjugates bearing electroactive labels

Julie Moreau , Nabil Dendane , Bernd Schöllhorn , Nicolas Spinelli , Claire Fave et al.
Bioorganic and Medicinal Chemistry Letters, 2013, 23 (4), pp.955 - 958. ⟨10.1016/j.bmcl.2012.12.057⟩
Article dans une revue istex hal-01653056 v1

Closer to nature: an ATP-driven bioinspired catalytic oxidation process

Loïc Stefan , Damien Duret , Nicolas Spinelli , Eric Defrancq , David Monchaud
Chemical Communications, 2013, 49 (15), pp.1500. ⟨10.1039/C2CC38317A⟩
Article dans une revue hal-02125740 v1

Electrogenerated trisbipyridyl Ru(II)-/nitrilotriacetic-polypyrene copolymer for the easy fabrication of label-free photoelectrochemical immunosensor and aptasensor: Application to the determination of thrombin and anti-cholera toxinantibody

Yao Wenjuan , Alan Le Goff , Nicolas Spinelli , Michael Holzinger , Guo-Wang Diao et al.
Biosensors and Bioelectronics, 2013, 42, pp.556 - 562. ⟨10.1016/j.bios.2012.11.013⟩
Article dans une revue istex hal-01652746 v1

High affinity glycodendrimers for the lectin LecB from <i>Pseudomonas aeruginosa</i>

Nathalie Berthet , Baptiste Thomas , Isabelle Bossu , Emilie Dufour , Emilie Gillon et al.
Bioconjugate Chem., 2013, pp.1598-1611. ⟨10.1021/bc400239m⟩
Article dans une revue hal-00903491 v1

Click–click chemistry on a peptidic scaffold for easy access to tetrameric DNA structures

Romaric Bonnet , Pierre Murat , Nicolas Spinelli , Eric Defrancq
Chemical Communications, 2012, 48 (48), ⟨10.1039/c2cc32010j⟩
Article dans une revue hal-01654796 v1

The Use of a Peptidic Scaffold for the Formation of Stable Guanine Tetrads: Control of a H-bonded Pattern in Water

Pierre Murat , Béatrice Gennaro , Julian Garcia , Nicolas Spinelli , Pascal Dumy et al.
Chemistry - A European Journal, 2011, 17 (21), pp.5791 - 5795. ⟨10.1002/chem.201003556⟩
Article dans une revue istex hal-01655632 v1

Molecular engineering of biomolecules for nanobio-sciences

Olivier Renaudet , Julian Garcia , Didier Boturyn , Nicolas Spinelli , Eric Defrancq et al.
International Journal of Nanotechnology, 2010, 7 (4/5/6/7/8), ⟨10.1504/IJNT.2010.031742⟩
Article dans une revue hal-01658284 v1

Oligonucleotide sequential bis-conjugation via click-oxime and click-Huisgen procedures.

Albert Meyer , Nicolas Spinelli , Pascal Dumy , Jean-Jacques Vasseur , François Morvan et al.
Journal of Organic Chemistry, 2010, 75, pp.3927-3930. ⟨10.1021/jo100599m⟩
Article dans une revue hal-00519475 v1

Template-Assembled Synthetic G-Quadruplex (TASQ): A Useful System for Investigating the Interactions of Ligands with Constrained Quadruplex Topologies

Pierre Murat , Romaric Bonnet , Angéline Van der heyden , Nicolas Spinelli , Pierre Labbé et al.
Chemistry - A European Journal, 2010, 16 (20), pp.6106 - 6114. ⟨10.1002/chem.200903456⟩
Article dans une revue istex hal-01658627 v1

Efficient conjugation of oligonucleotides through aromatic oxime formation

Pierre Murat , Nicolas Spinelli , Pascal Dumy , Eric Defrancq
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (23), pp.6534 - 6537. ⟨10.1016/j.bmcl.2009.10.048⟩
Article dans une revue istex hal-01658963 v1

A Novel Conformationally Constrained Parallel G Quadruplex

Pierre Murat , Delphine Cressend , Nicolas Spinelli , Angéline van der Heyden , Pierre Labbé et al.
ChemBioChem, 2008, 9 (16), pp.2588-2591. ⟨10.1002/cbic.200800457⟩
Article dans une revue hal-04823402 v1

New solid support for the synthesis of 3 '-oligonucleotide conjugates through glyoxylic oxime bond formation

Nicolas Spinelli , Om Prakash Edupuganti , Eric Defrancq , Pascal Dumy
Organic Letters, 2007, 9, pp.219-222. ⟨10.1021/ol062607b⟩
Article dans une revue hal-00169469 v1

Synthesis and electropolymerization studies of water-soluble pyrrole-ferrocene derivatives towards biochip device application

C. Farre , N. Spinelli , Alexandra Bouchet , C.A. Marquette , B. Mandrand et al.
Synthetic Metals, 2007, 157 (2-3), pp.125-133
Article dans une revue hal-00287095 v1

Aldehydic Oligonucleotide: A Key Intermediate for the Preparation of Oligonucleotide Conjugates Through Oxime Bond Formation

Nicolas Spinelli , Yogendra Singh , Éric Defrancq , Pascal Dumy
Nucleosides, Nucleotides and Nucleic Acids, 2007, 26 (8-9), pp.883-887. ⟨10.1080/15257770701505436⟩
Article dans une revue hal-04823327 v1

The first automated synthesis of ferrocene-labelled phosphorothioate DNA probe: A new potential tool for the fabrication of DNA microarrays.

Hugues Brisset , Aude-Emmanuelle Navarro , Nicolas Spinelli , Carole Chaix , Bernard Mandrand
Biotechnology Journal, 2006, 1, pp.95-98. ⟨10.1002/biot200500004⟩
Article dans une revue hal-00021563 v1

Characterization of PEDOT film functionalized with a series of automated synthesis ferrocenyl-containing oligonucleotides

Aude-Emmanuelle Navarro , Frédéric Fages , Corinne Moustrou , Hugues Brisset , Nicolas Spinelli et al.
Tetrahedron, 2005, 61 (16), pp.3947-3952. ⟨10.1016/j.tet.2005.02.058⟩
Article dans une revue istex hal-03409069 v1

Supported synthesis of ferrocene modified oligonucleotides as new electroactive DNA probes

Aude-Emmanuelle Navarro , Nicolas Spinelli , Carole Chaix , Corinne Moustrou , Bernard Mandrand et al.
Bioorganic and Medicinal Chemistry Letters, 2004, 14 (10), pp.2439-2441. ⟨10.1016/j.bmcl.2004.03.016⟩
Article dans une revue istex hal-03409059 v1
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Automated synthesis of new ferrocenyl-modified oligonucleotides: study of their properties in solution

A.-E. Navarro , Nicolas Spinelli , Corinne Moustrou , Carole Chaix , Bernard Mandrand et al.
Nucleic Acids Research, 2004, 32 (17), pp.5310-5319. ⟨10.1093/nar/gkh874⟩
Article dans une revue hal-03409350 v1

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Isabelle Baussanne , Nicolas Spinelli
ARCANE Scientific Day, Labex ARCANE, May 2023, Grenoble, France
Communication dans un congrès hal-04795236 v1

Development of a new detection method for small analytes based on the fluorogenic supramolecular assembly of aptamers

Rim Karkori , Nicolas Spinelli , Isabelle Baussanne
Journée Scientifique du Médicament 2023 : “Contributions of Click Chemistry and Light in Chemical Biology”, DPM, Jun 2023, Grenoble, France
Communication dans un congrès hal-04795206 v1

Recent advances in oxidation catalysis with ArMs based on a nickel-binding protein (NikA) and novel RG4s

Caroline Marchi- Delapierre , Sarah Lopez , Yoann Colas , Christine Cavazza , Nicolas Spinelli et al.
Artificial Proteins in the 21st Century: Designed (Metallo) proteins” Symposium, Apr 2022, Marseille, France
Communication dans un congrès hal-04564547 v1

Towards a new generation of electrical biosensors based on 2D silicon nanowire networks for DNA and Thrombin detection

Monica Vallejo Perez , Céline Ternon , Fanny Morisot , C Gondran , Karine Gorgy et al.
Nanotech France 2021, Jun 2021, Paris, France
Communication dans un congrès hal-04755031 v1

Constrained Oligonucleotides based chiral catalysts

Yoann Colas , Caroline Marchi- Delapierre , Nicolas Spinelli
2021 FrenchBIC Meeting, Oct 2021, Obernai, France
Communication dans un congrès hal-05045902 v1

Elaboration d’aptacapteurs à nanofils basés sur la détection électrique par effet de champ

Monica Vallejo Perez , Céline Ternon , Nicolas Spinelli , Valerie Stambouli
Journée scientifique du pôle PEM, IDEX grenoblois, Nov 2019, Grenoble, France
Communication dans un congrès hal-04756800 v1

New generation of FET aptasensors based on silicon nanowire networks for thrombin detection

Monica Vallejo Perez , Céline Ternon , Nicolas Spinelli , Xavier Mescot , Valerie Stambouli
Réunion d’automne du Club MicroCapteurs Chimiques (CMC2), Nov 2019, Marseille, France
Communication dans un congrès hal-04756746 v1

Towards Apta-NanoNetFET biosensors

Monica Vallejo Perez , F. Morisot , Céline Ternon , N. Spinelli , V. Stambouli
11th Ibero-American Congress on Sensors, Sep 2018, Barcelona, Spain
Communication dans un congrès hal-01981225 v1