Olivier Gadal

Co-directeur de l'équipe : Organisation et dynamique nucléaire. Molecular, Cellular and Developmental Biology Unit (MCD), CBI TOULOUSE: Toulouse, FR
39
Documents

Publications

11
11
5
4
2
2
2
1
1
3
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
10
8
7
7
7
6
6
6
5
4
4
4
4
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
21
12
5
4
3
2
1

Publications

Deposit thumbnail

Multiscale visualization of nucleolar chromatin in yeast Saccharomyces cerevisiae

Claudie Carron , Sarah Danché , Valdir Gomes Neto , Mickaël Lelek , Nana Kadidia Maiga et al.

Journal of Structural Biology, 2025, 217 (3), pp.108228. ⟨10.1016/j.jsb.2025.108228⟩

Article dans une revue hal-05261356v1
Deposit thumbnail

RNA Pol II-based regulations of chromosome folding

Christophe Chapard , Nathalie Bastié , Axel Cournac , Laura Chaptal , Henri Mboumba et al.

Cell Genomics, 2025, ⟨10.1016/j.xgen.2025.100970⟩

Article dans une revue hal-05121450v1
Deposit thumbnail

New insights into nuclear import and nucleolar localization of yeast RNA exosome subunits

Valdir Gomes Neto , Leidy Paola P Cepeda , Bruno R S Queiroz , Sylvain Cantaloube , Isabelle Leger-Silvestre et al.

Molecular Biology of the Cell, 2025, 36, ⟨10.1091/mbc.e25-02-0078⟩

Article dans une revue hal-05525328v1
Deposit thumbnail

Ribosomal RNA synthesis by RNA polymerase I is subject to premature termination of transcription

Chaïma Azouzi , Katrin Schwank , Sophie Queille , Marta Kwapisz , Marion Aguirrebengoa et al.

eLife, 2025, 14, ⟨10.7554/elife.106503.2⟩

Article dans une revue hal-05408786v1
Deposit thumbnail

RNA polymerase I mutant affects ribosomal RNA processing and ribosomal DNA stability

Christophe Normand , Christophe Dez , Lise Dauban , Sophie Queille , Sarah Danché et al.

RNA Biology, 2024, 21 (1), pp.1-16. ⟨10.1080/15476286.2024.2381910⟩

Article dans une revue hal-04738105v1

Sister chromatid cohesion halts DNA loop expansion

Nathalie Bastié , Christophe Chapard , Axel Cournac , Sanae Nejmi , Henri Mboumba et al.

Molecular Cell, 2024, 84 (6), pp.1139-1148.e5. ⟨10.1016/j.molcel.2024.02.004⟩

Article dans une revue pasteur-04603601v1
Deposit thumbnail

The dual life of disordered lysine-rich domains of snoRNPs in rRNA modification and nucleolar compaction

Carine Dominique , Nana Kadidia Maiga , Alfonso Méndez-Godoy , Benjamin Pillet , Hussein Hamze et al.

Nature Communications, 2024, Nat Commun. 2024 Oct 31;15:9415. doi: 10.1038/s41467-024-53805-1, 15 (1), pp.9415. ⟨10.1038/s41467-024-53805-1⟩

Article dans une revue hal-04797120v1

Smc3 acetylation, Pds5 and Scc2 control the translocase activity that establishes cohesin-dependent chromatin loops

Nathalie Bastié , Christophe Chapard , Lise Dauban , Olivier Gadal , Frederic Beckouet et al.

Nature Structural and Molecular Biology, 2022, 29 (6), pp.575-585. ⟨10.1038/s41594-022-00780-0⟩

Article dans une revue hal-03697578v1
Deposit thumbnail

Coupling between production of ribosomal RNA and maturation: just at the beginning

Chaima Azouzi , Mariam Jaafar , Christophe Dez , Raghida Abou Merhi , Annick Lesne et al.

Frontiers in Molecular Biosciences, In press, 8, pp.778778. ⟨10.3389/fmolb.2021.778778⟩

Article dans une revue hal-03380240v1
Deposit thumbnail

Non-Coding, RNAPII-Dependent Transcription at the Promoters of rRNA Genes Regulates Their Chromatin State in S. cerevisiae

Emma Lesage , Jorge Perez-Fernandez , Sophie Queille , Christophe Dez , Olivier Gadal et al.

Non-Coding RNA, 2021, 7 (3), pp.41. ⟨10.3390/ncrna7030041⟩

Article dans une revue hal-03409278v1
Deposit thumbnail

Regulation of Cohesin-Mediated Chromosome Folding by Eco1 and Other Partners

Lise Dauban , Rémi Montagne , Agnès Thierry , Luciana Lazar-Stefanita , Nathalie Bastié et al.

Molecular Cell, 2020, 77 (6), pp.1279-1293.e4. ⟨10.1016/j.molcel.2020.01.019⟩

Article dans une revue hal-03064572v1
Deposit thumbnail

Nucleolar localization of the yeast RNA exosome subunit Rrp44 hints at early pre-rRNA processing as its main function

Ellen Okuda , Fernando Gonzales-Zubiate , Olivier Gadal , Carla Oliveira

Journal of Biological Chemistry, 2020, 295 (32), pp.11195-11213. ⟨10.1074/jbc.RA120.013589⟩

Article dans une revue hal-04830100v1
Deposit thumbnail

Nuclear envelope expansion in budding yeast is independent of cell growth and does not determine nuclear volume

Alison Walters , Kwabena Amoateng , Renjie Wang , Jian-Hua Chen , Gerry Mcdermott et al.

Molecular Biology of the Cell, 2019, 30 (1), pp.131-145. ⟨10.1091/mbc.E18-04-0204⟩

Article dans une revue hal-04830049v1
Deposit thumbnail

Genetic analyses led to the discovery of a super-active mutant of the RNA polymerase I

Tommy Darrière , Michael Pilsl , Marie-Kerguelen Sarthou , Adrien Chauvier , Titouan Genty et al.

PLoS Genetics, 2019, 15 (5), pp.e1008157. ⟨10.1371/journal.pgen.1008157⟩

Article dans une revue hal-02362225v1
Deposit thumbnail

Rouse model with transient intramolecular contacts on a timescale of seconds recapitulates folding and fluctuation of yeast chromosomes

Marius Socol , Renjie Wang , Daniel Jost , Pascal Carrivain , Cédric Vaillant et al.

Nucleic Acids Research, 2019, 47 (12), pp.6195-6207. ⟨10.1093/nar/gkz374⟩

Article dans une revue hal-02276944v1
Deposit thumbnail

A ribosome assembly stress response regulates transcription to maintain proteome homeostasis

Benjamin Albert , Isabelle Kos-Braun , Anthony K Henras , Christophe Dez , Maria Paula Rueda et al.

eLife, 2019, 8, pp.e45002. ⟨10.7554/eLife.45002⟩

Article dans une revue hal-02416945v1
Deposit thumbnail

Excessive rDNA Transcription Drives the Disruption in Nuclear Homeostasis during Entry into Senescence in Budding Yeast

Sandrine Morlot , Jia Song , Isabelle Léger-Silvestre , Audrey Matifas , Olivier Gadal et al.

Cell Reports, 2019, 28 (2), pp.408-422.e4. ⟨10.1016/j.celrep.2019.06.032⟩

Article dans une revue hal-03096871v1
Deposit thumbnail

Meeting report from the first European OddPols meeting: Toulouse 2018

Lise Dauban , Emilie Cerezo , Anthony K Henras , Olivier Gadal

Gene, 2019, 702, pp.215-219. ⟨10.1016/j.gene.2018.12.051⟩

Article dans une revue hal-02416943v1
Deposit thumbnail

Quantification of the dynamic behaviour of ribosomal DNA genes and nucleolus during yeast Saccharomyces cerevisiae cell cycle

Lise Dauban , Alain Kamgoué , Renjie Wang , Isabelle Léger-Silvestre , Frédéric Beckouët et al.

Journal of Structural Biology, 2019, 208, pp.152 - 164. ⟨10.1016/j.jsb.2019.08.010⟩

Article dans une revue hal-03034506v1
Deposit thumbnail

Turnover of aberrant pre-40S pre-ribosomal particles is initiated by a novel endonucleolytic decay pathway

Élodie Choque , Claudia Schneider , Olivier Gadal , Christophe Dez

Nucleic Acids Research, 2018, 46 (9), pp.4699-4714. ⟨10.1093/nar/gky116⟩

Article dans une revue hal-03040614v1
Deposit thumbnail

Principles of chromatin organization in yeast: relevance of polymer models to describe nuclear organization and dynamics

Renjie Wang , Julien Mozziconacci , Aurélien Bancaud , Olivier Gadal

Current Opinion in Cell Biology, 2015, 34, pp.54 - 60. ⟨10.1016/j.ceb.2015.04.004⟩

Article dans une revue hal-01682615v1
Deposit thumbnail

Systematic characterization of the conformation and dynamics of budding yeast chromosome XII

Benjamin Albert , Julien Mathon , Ashutosh Shukla , Hicham Saad , Christophe Normand et al.

Journal of Cell Biology, 2013, 202 (2), pp.201-210. ⟨10.1083/jcb.201208186⟩

Article dans une revue hal-01682609v2
Deposit thumbnail

High-throughput chromatin motion tracking in living yeast reveals the flexibility of the fiber throughout the genome

Houssam Hajjoul , Julien Mathon , Hubert Ranchon , Pascal Carrivain , Isabelle Goiffon et al.

Genome Research, 2013, 23 (11), pp.1829-1838. ⟨10.1101/gr.157008.113⟩

Article dans une revue hal-01053149v1

Mutations in TFIIH causing trichothiodystrophy are responsible for defects in ribosomal RNA production and processing

Julie Nonnekens , Jorge Perez-Fernandez , Arjan F Theil , Olivier Gadal , Chrystelle Bonnart et al.

Human Molecular Genetics, 2013, 22 (14), pp.2881-2893. ⟨10.1093/hmg/ddt143⟩

Article dans une revue hal-02148341v1

Nuclear organization and chromatin dynamics in yeast: Biophysical models or biologically driven interactions?

Benjamin Albert , Isabelle Léger-Silvestre , Christophe Normand , Olivier Gadal

BBA - Biochimica et Biophysica Acta, 2012, epub ahead of print. ⟨10.1016/j.bbagrm.2011.12.010⟩

Article dans une revue istex hal-00667376v1
Deposit thumbnail

RNA polymerase I-specific subunits promote polymerase clustering to enhance the rRNA gene transcription cycle.

Benjamin Albert , Isabelle Léger-Silvestre , Christophe Normand , Martin K Ostermaier , Jorge Pérez-Fernández et al.

Journal of Cell Biology, 2011, 192 (2), pp.277-93. ⟨10.1083/jcb.201006040⟩

Article dans une revue hal-00667459v1

The nucleolar protein Nop19p interacts preferentially with Utp25p and Dhr2p and is essential for the production of the 40S ribosomal subunit in Saccharomyces cerevisiae.

Élodie Choque , Marlène Marcellin , Odile Burlet-Schiltz , Olivier Gadal , Christophe Dez

RNA Biology, 2011, 8 (6), pp.1158-72. ⟨10.4161/rna.8.6.17699⟩

Article dans une revue hal-00667454v1

Genome organization and function: a view from yeast and Arabidopsis.

Julio Sáez-Vásquez , Olivier Gadal

Molecular Plant, 2010, 3 (4), pp.678-90. ⟨10.1093/mp/ssq034⟩

Article dans une revue hal-00787670v1

Two RNA polymerase I subunits control the binding and release of Rrn3 during transcription.

Frédéric Beckouet , Sylvie Labarre-Mariotte , Benjamin Albert , Yukiko Imazawa , Michel Werner et al.

Molecular and Cellular Biology, 2008, 28 (5), pp.1596-605. ⟨10.1128/MCB.01464-07⟩

Article dans une revue hal-00309037v1

Cell cycle-dependent kinetochore localization of condensin complex in Saccharomyces cerevisiae.

Sophie Bachellier-Bassi , Olivier Gadal , Gaelle Bourout , Ulf Nehrbass

Journal of Structural Biology, 2008, 162 (2), pp.248-59. ⟨10.1016/j.jsb.2008.01.002⟩

Article dans une revue istex pasteur-00276345v1

Hmo1 is required for TOR-dependent regulation of ribosomal protein gene transcription.

Axel B Berger , Laurence Decourty , Gwenaël Badis , Ulf Nehrbass , Alain Jacquier et al.

Molecular and Cellular Biology, 2007, 27 (22), pp.8015-26. ⟨10.1128/MCB.01102-07⟩

Article dans une revue hal-00309038v1

RNA polymerase I-specific subunit CAST/hPAF49 has a role in the activation of transcription by upstream binding factor.

Kostya I Panov , Tatiana B Panova , Olivier Gadal , Kaori Nishiyama , Takashi Saito et al.

Molecular and Cellular Biology, 2006, 26 (14), pp.5436-48. ⟨10.1128/MCB.00230-06⟩

Article dans une revue hal-00309039v1
Deposit thumbnail

SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope.

Ghislain G Cabal , Auguste Genovesio , Susana Rodriguez-Navarro , Christophe Zimmer , Olivier Gadal et al.

Nature, 2006, 441 (7094), pp.770-3. ⟨10.1038/nature04752⟩

Article dans une revue istex pasteur-00207343v1

Nuclear Retention of Unspliced mRNAs in Yeast Is Mediated by Perinuclear Mlp1

Vincent Galy , Olivier Gadal , Micheline Fromont-Racine , Alper Romano , Alain Jacquier et al.

Cell, 2004, 116 (1), pp.63-73. ⟨10.1016/s0092-8674(03)01026-2⟩

Article dans une revue hal-02373489v1

The Nucle(ol)ar Tif6p and Efl1p Are Required for a Late Cytoplasmic Step of Ribosome Synthesis

Bruno Senger , Denis L.J. Lafontaine , Jean-Sebastien Graindorge , Olivier Gadal , Alain Camasses et al.

Molecular Cell, 2001, 8 (6), pp.1363-1373. ⟨10.1016/s1097-2765(01)00403-8⟩

Article dans une revue hal-02370147v1

Chromosome dynamics & transcription: dissection of chromatin structural properties in living yeast

Aurélien Bancaud , Marius Socol , Victor Conde , Renjie Wang , Olivier Gadal

4th International Symposium of the Mathematics on Chromatin Live Dynamics ( ISMCD 2015), Dec 2015, Hiroshima, Japan

Communication dans un congrès hal-02012200v1