PR

Pascal Rihet

83
Documents

Présentation

Le parcours académique de Pascal Rihet a débuté à l'École Normale Supérieure (ENS) de Saint-Cloud, où il a été élève normalien de 1982 à 1986. Pascal Rihet a obtenu son doctorat en immunologie à l'Université de la Méditerranée pour ses travaux sur le rôle protecteur des IgE dans la schistosomiase. Il a été nommé maître de conférences en immunologie à l'Université de la Méditerranée en 1992. Il a été promu professeur titulaire de génomique à l'université d'Aix-Marseille en 2008. Il a dirigé le master en bio-informatique, biologie structurale et génomique de 2008 à 2017. Il a supervisé la thèse de doctorat de 16 étudiants et a participé à 65 jurys de thèse et HDR. Il a été membre du conseil de l'école doctorale des sciences de la vie et de la santé ED62 de 2007 à 2024. Par ailleurs, il a été directeur adjoint ou directeur du laboratoire TAGC, une unité de recherche labellisée par l’INSERM et Aix-Marseille Université, de 2012 à 2026.

Ses recherches portent sur la génétique et la génomique de maladies multifactorielles, telles que le paludisme, le sepsis, la Covid-19 et le cancer (le projet principal concernant le paludisme). L'objectif global est d'identifier les gènes, les réseaux de gènes et leurs variations impliqués dans le contrôle de l'infection, l'élimination des cellules tumorales et l'apparition de la maladie. Le projet combine une approche de clonage positionnel chez l'homme et la souris, des études transcriptomiques, des analyses bioinformatiques et une validation expérimentale sur des modèles animaux et des modèles cellulaires. Il a i) identifié des signatures transcriptionnelles associées à des phénotypes cliniques, ii) cartographié plusieurs gènes impliqués dans le paludisme et le sepsis chez l'homme ou la souris, et iii) identifié plusieurs variants génétiques régulateurs situés dans des promoteurs, des enhancers ou des silencers, ayant un impact à la fois sur l’expression des gènes et sur les phénotypes cliniques.

Publications

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Publications

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A Functional Intronic Variant of LILRB1 Associated with Clinical Malaria in the Senegalese Population

Christelle Dieppois , Gaël Chambonnier , Frederic Gallardo , Magali Torres , Alassane Thiam et al.
Journal of Infectious Diseases, 2026, Online ahead of print. ⟨10.1093/infdis/jiag007⟩
Article dans une revue hal-05443497 v1
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Unraveling an enhancer-silencer regulatory element showing epistatic interaction with a variant that escaped genome-wide association studies

Mathieu Adjemout , Samia Nisar , Amélie Escandell , Romain Torres , Magali Torres et al.
Cell Genomics, 2025, 5 (7), pp.100889. ⟨10.1016/j.xgen.2025.100889⟩
Article dans une revue hal-05173109 v1
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An Expression Quantitative Trait Locus of Fc Gamma Receptor Genes is Associated with Anti-Malarial IgG Responses and Infection Levels in Burkinabe Families Running Title: Association of rs1771575 with Malaria

Christelle Dieppois , Mathieu Adjemout , Jules Cretin , Frederic Gallardo , Magali Torres et al.
Journal of Infectious Diseases, In press, 2231 (4), pp.1008-1019. ⟨10.1093/infdis/jiae528⟩
Article dans une revue hal-04750444 v1
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From Genome-wide Association Studies to Functional Variants: ARL14 Cis - regulatory Variants Are Associated With Severe Malaria

Mathieu Adjemout , Frederic Gallardo , Magali Torres , Alassane Thiam , Babacar Mbengue et al.
Journal of Infectious Diseases, 2024, pp.jiae159. ⟨10.1093/infdis/jiae159⟩
Article dans une revue hal-04549763 v1
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Concurrent PIEZO1 activation and ATP2B4 blockade effectively reduce the risk of cerebral malaria and inhibit in vitro Plasmodium falciparum multiplication in red blood cells

Mathieu Adjemout , Bruno Pouvelle , Fatou Thiam , Alassane Thiam , Magali Torres et al.
Genes & Diseases, 2023, 10 (6), pp.2210-2214. ⟨10.1016/j.gendis.2023.02.029⟩
Article dans une revue hal-04179608 v1
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A Non-Coding Fc Gamma Receptor Cis-Regulatory Variant within the 1q23 Gene Cluster Is Associated with Plasmodium falciparum Infection in Children Residing in Burkina Faso

Jules Cretin , Mathieu Adjemout , Christelle Dieppois , Frederic Gallardo , Magali Torres et al.
International Journal of Molecular Sciences, 2023, 24 (21), pp.15711. ⟨10.3390/ijms242115711⟩
Article dans une revue hal-04268017 v1
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The Contribution of Multiplexing Single Cell RNA Sequencing in Acute Myeloid Leukemia

Lamia Madaci , Charlyne Gard , Sébastien Nin , Geoffroy Venton , Pascal Rihet et al.
Diseases, 2023, 11 (3), pp.96. ⟨10.3390/diseases11030096⟩
Article dans une revue hal-04161267 v1
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Single-Cell Transcriptome Analysis of Acute Myeloid Leukemia Cells Using Methanol Fixation and Cryopreservation

Lamia Madaci , Charlyne Gard , Sébastien Nin , Alexandre Sarrabay , Céline Baier et al.
Diseases, 2023, 12 (1), pp.1. ⟨10.3390/diseases12010001⟩
Article dans une revue hal-04501292 v1
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ATP2B4 regulatory genetic variants are associated with mild malaria

Alassane Thiam , Samia Nisar , Mathieu Adjemout , Frederic Gallardo , Oumar Ka et al.
Malaria Journal, 2023, 22 (68), ⟨10.1186/s12936-023-04503-8⟩
Article dans une revue hal-04006760 v1
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Transcriptional Response in a Sepsis Mouse Model Reflects Transcriptional Response in Sepsis Patients

Florian Rosier , Nicolas Fernandez Nuñez , Magali Torres , Béatrice B. Loriod , Pascal Rihet et al.
International Journal of Molecular Sciences, 2022, 23 (2), pp.821. ⟨10.3390/ijms23020821⟩
Article dans une revue hal-03528060 v1
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Identification of ATP2B4 Regulatory Element Containing Functional Genetic Variants Associated with Severe Malaria

Samia Nisar , Magali Torres , Alassane Thiam , Bruno Pouvelle , Florian Rosier et al.
International Journal of Molecular Sciences, 2022, 23 (9), pp.4849. ⟨10.3390/ijms23094849⟩
Article dans une revue hal-03690258 v1
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Genetic Predisposition to the Mortality in Septic Shock Patients: From GWAS to the Identification of a Regulatory Variant Modulating the Activity of a CISH Enhancer

Florian Rosier , Audrey Brisebarre , Claire Dupuis , Sabrina Baaklini , Denis Puthier et al.
International Journal of Molecular Sciences, 2021, 22, ⟨10.3390/ijms22115852⟩
Article dans une revue hal-03245766 v1
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Gene expression profiling in blood from cerebral malaria patients and mild malaria patients living in Senegal

Alassane Thiam , Michel Sanka , Rokhaya Ndiaye Diallo , Magali Torres , Babacar Mbengue et al.
BMC Medical Genomics, 2019, 12 (1), pp.148. ⟨10.1186/s12920-019-0599-z⟩
Article dans une revue hal-02340853 v1
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TAGOOS: genome-wide supervised learning of non-coding loci associated to complex phenotypes

Aitor Gonzalez , Marie Artufel , Pascal Rihet
Nucleic Acids Research, 2019, ⟨10.1093/nar/gkz320⟩
Article dans une revue hal-02119716 v1
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A transcriptomic signature predicting septic outcome in patients undergoing autologous stem cell transplantation

Yasmine Labiad , Geoffroy Venton , Farnault Laure , Céline Baier , Julien Colle et al.
Experimental Hematology, 2018, ⟨10.1016/j.exphem.2018.06.001⟩
Article dans une revue hal-01850637 v1
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Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia

Ngoc Thy Nguyen , Romain R Vivès , Magali Iché-Torres , Vincent Delauzun , Els Saesen et al.
Glycobiology, 2018, 28 (7), pp.534-541. ⟨10.1093/glycob/cwy038⟩
Article dans une revue hal-02045171 v1
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NCR3 polymorphism, haematological parameters, and severe malaria in Senegalese patients

Alassane Thiam , Sabrina Baaklini , Babacar Mbengue , Samia Nisar , Maryam Diarra et al.
PeerJ, 2018, 6, pp.e6048. ⟨10.7717/peerj.6048⟩
Article dans une revue hal-01947567 v1
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Deletion of Nkx2-5 in trabecular myocardium reveals the developmental origins of pathological heterogeneity associated with ventricular non-compaction cardiomyopathy

Caroline Choquet , Thi Hong Minh Nguyen , Pierre Sicard , Emeline Buttigieg , Thi Thom Tran et al.
PLoS Genetics, 2018, 14 (7), pp.e1007502. ⟨10.1371/journal.pgen.1007502⟩
Article dans une revue hal-01832385 v1
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Vorinostat and Mithramycin A in combination therapy as an interesting strategy for the treatment of Sézary T lymphoma: a transcriptomic approach

R. Ragheb , G. Venton , R. Chelbi , N. Bonnet , T. Le Treut et al.
Archives of Dermatological Research, 2017, 309 (8), pp.611-623. ⟨10.1007/s00403-017-1761-0⟩
Article dans une revue hal-01595894 v1
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Interplay between trauma and Pseudomonas entomophila infection in flies: a central role of the JNK pathway and of CrebA

Ramy Ragheb , Alexandre Chuyen , Magali Torres , Arnaud Defaye , Denis Seyres et al.
Scientific Reports, 2017, 7 (1), pp.16222. ⟨10.1038/s41598-017-14969-7⟩
Article dans une revue hal-01662954 v1
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Beyond genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo

Sabrina Baaklini , Sarwat Afridi , Thy Ngoc Nguyen , Felix Koukouikila-Koussounda , Mathieu Ndounga et al.
PLoS ONE, 2017, 12 (11), pp.e0187818. ⟨10.1371/journal.pone.0187818⟩
Article dans une revue hal-01633311 v1

Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a congolese population

T. N. Nguyen , S. Baaklini , F. Koukouikila-Koussounda , M. Ndounga , M. Torres et al.
Genes and Immunity, 2017, ⟨10.1038/gene.2017.13⟩
Article dans une revue hal-01595896 v1

Natural killer cells in acute myeloid leukemia patients: from phenotype to transcriptomic analysis

G. Venton , Y. Labiad , J. Colle , A. Fino , S. Afridi et al.
Immunologic Research, 2016, 64 (5-6), pp.1225-1236. ⟨10.1007/s12026-016-8848-0⟩
Article dans une revue hal-01460129 v1

Technical data of the transcriptomic analysis performed on tsetse fly symbionts, Sodalis glossinidius and Wigglesworthia glossinidia, harbored, respectively by non-infected, Trypanosoma brucei gambiense infected and self-cured Glossina palpalis gambiensis tsetse flies

Anne Geiger , Bernadette Tchicaya , Pascal Rihet
Genomics Data, 2015, 4, pp.133-136. ⟨10.1016/j.gdata.2015.04.007⟩
Article dans une revue hal-01595897 v1

Serum Pantetheinase/Vanin Levels Regulate Erythrocyte Homeostasis and Severity of Malaria

Samuel Rommelaere , Virginie Millet , Pascal Rihet , Scott Atwell , Emmanuèle Helfer et al.
American Journal of Pathology, 2015, 185 (11), pp.3039-3052. ⟨10.1016/j.ajpath.2015.07.011⟩
Article dans une revue hal-01595898 v1

Natural killer cells in patients with polycythemia vera

Carole Sanchez , Céline Baier , Julien G. Colle , Rabie Chelbi , Pascal Rihet et al.
Human Immunology, 2015, 76 (9), pp.644-650. ⟨10.1016/j.humimm.2015.09.010⟩
Article dans une revue hal-01595901 v1

Genome-wide significant linkage to IgG subclass responses against Plasmodium falciparum antigens on chromosomes 8p22-p21, 9q34 and 20q13

A. Brisebarre , B. Kumulungui , S. Sawadogo , S. Afridi , F. Fumoux et al.
Genes and Immunity, 2015, 16 (3), pp.187-192. ⟨10.1038/gene.2014.66⟩
Article dans une revue hal-01595902 v1

Inflammation and sepsis as part of hematopoietic stem cell transplantation: a transcriptomic approach

Y. Labiad , C. Mercier , I. Vadim , L. Farnault , J. Colle et al.
Bone Marrow Transplantation, 2015, 50, pp.S418
Article dans une revue hal-01595899 v1

Sperm mRNAs and microRNAs as candidate markers for the impact of toxicants on human spermatogenesis: an application to tobacco smoking

Catherine Metzler-Guillemain , Genevieve Victorero , Cyrille Lepoivre , Aurélie Bergon , Miriam Yammine et al.
Systems Biology in Reproductive Medicine, 2015, 61 (3), pp.139--149. ⟨10.3109/19396368.2015.1022835⟩
Article dans une revue hal-01445195 v1

Identification of AREG and PLK1 pathway modulation as a potential key of the response of intracranial 9L tumor to microbeam radiation therapy

Audrey Bouchet , Nathalie Sakakini , Michèle El Atifi , Céline Le Clec'H , Elke Braeuer-Krisch et al.
International Journal of Cancer, 2015, 136 (11), pp.2705-2716. ⟨10.1002/ijc.29318⟩
Article dans une revue hal-01595900 v1
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A genome scan for Plasmodium falciparum malaria identifies quantitative trait loci on chromosomes 5q31, 6p21.3, 17p12, and 19p13

Audrey Brisebarre , Brice Kumulungui , Serge Sawadogo , Alexandre Atkinson , Séverine Garnier et al.
Malaria Journal, 2014, 13, pp.198. ⟨10.1186/1475-2875-13-198⟩
Article dans une revue hal-01461374 v1

Identification of AREG and PLK1 pathway modulation as a potential key of the response of intracranial 9L tumor to microbeam radiation therapy

Audrey Bouchet , Nathalie Sakakini , Michèle El Atifi , Céline Le Clec'H , Elke Bräuer-Krisch et al.
International Journal of Cancer, 2014, 136 (11), pp.2705-2716. ⟨10.1002/ijc.29318⟩
Article dans une revue hal-05142300 v1

Host susceptibility to malaria in human and mice: compatible approaches to identify potential resistant genes

Maria Hernandez-Valladares , Pascal Rihet , Fuad A. Iraqi
Physiological Genomics, 2014, 46 (1), pp.1-16. ⟨10.1152/physiolgenomics.00044.2013⟩
Article dans une revue hal-01595905 v1

The transcriptional signatures of Sodalis glossinidius in the Glossina palpalis gambiensis flies negative for Trypanosoma brucei gambiense contrast with those of this symbiont in tsetse flies positive for the parasite: possible involvement of a Sodalis-hosted prophage in fly Trypanosoma refractoriness?

Illiassou Hamidou Soumana , Béatrice B. Loriod , Sophie Ravel , Bernadette Tchicaya , Gustave Simo et al.
Infection, Genetics and Evolution, 2014, 24, pp.41-56. ⟨10.1016/j.meegid.2014.03.005⟩
Article dans une revue istex hal-01612139 v1
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Approaches combining mice and Drosophila melanogaster models to decipher human sepsis

R Ramy , S Garnier , Lydie Pradel , Laurence Röder , Béatrice B. Loriod et al.
Critical Care, 2014, 18 (S2), ⟨10.1186/cc14070⟩
Article dans une revue hal-01619083 v1
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Identification of overexpressed genes in Sodalis glossinidius inhabiting trypanosome-infected self-cured tsetse flies

Illiassou Hamidou Soumana , Bernadette Tchicaya , Béatrice B. Loriod , Pascal Rihet , Anne Geiger
Frontiers in Microbiology, 2014, 5, pp.255. ⟨10.3389/fmicb.2014.00255⟩
Article dans une revue hal-01612141 v1

Functional Polymorphisms in the Regulatory Regions of the VNN1 Gene Are Associated with Susceptibility to Inflammatory Bowel Diseases

Thomas Gensollen , Christophe Bourges , Pascal Rihet , Agathe Rostan , Virginie Millet et al.
Inflammatory Bowel Diseases, 2013, 19 (11), pp.2315-2325. ⟨10.1097/MIB.0b013e3182a32b03⟩
Article dans une revue hal-01595906 v1

Early Gene Expression Analysis in 9L Orthotopic Tumor-Bearing Rats Identifies Immune Modulation in Molecular Response to Synchrotron Microbeam Radiation Therapy

Audrey Bouchet , Nathalie Sakakini , Michèle El Atifi , Céline Le Clec'H , Elke Brauer et al.
PLoS ONE, 2013, 8 (12), pp.e81874. ⟨10.1371/journal.pone.0081874⟩
Article dans une revue hal-05142307 v1
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Early gene expression analysis in 9L orthotopic tumor-bearing rats identifies immune modulation in molecular response to synchrotron microbeam radiation therapy.

Audrey Bouchet , Nathalie Sakakini , Michèle El Atifi , Céline Le Clec'H , Elke Brauer et al.
PLoS ONE, 2013, 8 (12), pp.e81874. ⟨10.1371/journal.pone.0081874⟩
Article dans une revue inserm-00955553 v1
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Natural killer cells modulation in hematological malignancies

Céline T Baier , Aurore T Fino , Carole T Sanchez , Laure Farnault , Pascal Rihet et al.
Frontiers in Immunology, 2013, NK and lymphoid cell biology (4), pp.459. ⟨10.3389/fimmu.2013.00459⟩
Article dans une revue hal-01455668 v1
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Striatal molecular signature of subchronic subthalamic nucleus high frequency stimulation in parkinsonian rat

Sylviane Lortet , Emilie Lacombe , Nicolas Boulanger , Pascal Rihet , Catherine Nguyen et al.
PLoS ONE, 2013, 8 (4), pp.e60447. ⟨10.1371/journal.pone.0060447⟩
Article dans une revue hal-00862146 v1
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Malaria resistance genes are associated with the levels of IgG subclasses directed against Plasmodium falciparum blood-stage antigens in Burkina Faso.

Sarwat Afridi , Alexandre Atkinson , Séverine Garnier , Francis Fumoux , Pascal Rihet
Malaria Journal, 2012, 11 (1), pp.308. ⟨10.1186/1475-2875-11-308⟩
Article dans une revue inserm-00780329 v1
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Coping with genetic diversity: the contribution of pathogen and human genomics to modern vaccinology

Denise Lemaire , Theoliz Barbosa , Pascal Rihet
Brazilian Journal of Medical and Biological Research, 2012, 45 (5), pp.376-385. ⟨10.1590/S0100-879X2011007500142⟩
Article dans une revue hal-01455691 v1

IL-12Rβ2 is essential for the development of experimental cerebral malaria.

Mathilde Fauconnier , Jennifer Palomo , Marie-Laure Bourigault , Sandra Meme , Frédéric Szeremeta et al.
Journal of Immunology, 2012, 188 (4), pp.1905-14. ⟨10.4049/jimmunol.1101978⟩
Article dans une revue hal-00721858 v1
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Genetic variations in genes involved in heparan sulphate biosynthesis are associated with Plasmodium falciparum parasitaemia: a familial study in Burkina Faso.

Alexandre Atkinson , Séverine Garnier , Sarwat Afridi , Francis Fumoux , Pascal Rihet
Malaria Journal, 2012, 11 (1), pp.108. ⟨10.1186/1475-2875-11-108⟩
Article dans une revue inserm-00703058 v1

Evidence for epistasis between hemoglobin C and immune genes in human P. falciparum malaria: a family study in Burkina Faso

A. Atkinson , M. Barbier , S. Afridi , F. Fumoux , P. Rihet
Genes and Immunity, 2011, 12 (6), pp.481-489. ⟨10.1038/gene.2011.19⟩
Article dans une revue hal-01595908 v1

Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors.

Nicolas F Delahaye , Sylvie Rusakiewicz , Isabelle Martins , Cédric Ménard , Stephan Roux et al.
Nature Medicine, 2011, 17 (6), pp.700-7. ⟨10.1038/nm.2366⟩
Article dans une revue hal-00665651 v1
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Platelets Alter Gene Expression Profile in Human Brain Endothelial Cells in an In Vitro Model of Cerebral Malaria

Mathieu Barbier , Dorothée Faille , Béatrice B. Loriod , Julien Textoris , Claire Camus et al.
PLoS ONE, 2011, 6 (5), pp.e19651. ⟨10.1371/journal.pone.0019651⟩
Article dans une revue hal-01743259 v1

Peripheral T-cell lymphoma gene expression profiling and potential therapeutic exploitations

Régis Costello , Carole Sanchez , Therese Le Treut , Pascal Rihet , Jean Imbert et al.
British Journal of Haematology, 2010, 150 (1), pp.21-27
Article dans une revue hal-01595909 v1
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Genome-Wide Expression Profiling Deciphers Host Responses Altered during Dengue Shock Syndrome and Reveals the Role of Innate Immunity in Severe Dengue

Stephanie Devignot , Cedric Sapet , Veasna Duong , Aurélie Bergon , Pascal Rihet et al.
PLoS ONE, 2010, 5 (7), ⟨10.1371/journal.pone.0011671⟩
Article dans une revue hal-01595911 v1

Family-based association of a low producing lymphotoxin-alpha allele with reduced Plasmodium falciparum parasitemia

Mathieu Barbier , Nicolas F. Delahaye , Francis Fumoux , Pascal Rihet
Microbes and Infection, 2008, 10 (6), pp.673-679
Article dans une revue hal-01595913 v1

IL12B polymorphisms are linked but not associated with Plasmodium falciparum parasitemia: a familial study in Burkina Faso

M. Barbier , A. Atkinson , F. Fumoux , P. Rihet
Genes and Immunity, 2008, 9 (5), pp.405-411
Article dans une revue hal-01595912 v1

Association analyses of NCR3 polymorphisms with P-falciparum mild malaria

Nicolas F. Delahaye , Mathieu Barbier , Francis Fumoux , Pascal Rihet
Microbes and Infection, 2007, 9 (2), pp.160-166. ⟨10.1016/j.micinf.2006.11.002⟩
Article dans une revue istex hal-01595914 v1

Gene expression analysis reveals early changes in several molecular pathways in cerebral malaria-susceptible mice versus cerebral malaria-resistant mice

N. F. Delahaye , N. Coltel , Denis Puthier , M. Barbier , P. Benech et al.
BMC Genomics, 2007, 8, pp.452
Article dans une revue hal-01595820 v1

Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice.

N.F. Delahaye , N. Coltel , D. Puthier , Laurence Flori , R. Houlgatte et al.
Journal of Infectious Diseases, 2006, 193, pp.312-321
Article dans une revue hal-02654443 v1
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Gene-expression profiling discriminates between cerebral malaria (CM)-susceptible mice and CM-resistant mice.

Nicolas F. Delahaye , Nicolas Coltel , Denis Puthier , Laurence Flori , Rémi Houlgatte et al.
Journal of Infectious Diseases, 2006, 193 (2), pp.312-21. ⟨10.1086/498579⟩
Article dans une revue inserm-00276272 v1

Pathology of Tnf-deficient mice infected with Plasmodium chabaudi adami 408XZ

M. Hernandez-Valladares , J. Naessens , A. J. Musoke , K. Sekikawa , P. Rihet et al.
Experimental Parasitology, 2006, 114 (4), pp.271-278
Article dans une revue hal-01595915 v1

Influence of carriage of hemoglobin AS and the Fc gamma receptor IIa-R-131 allele on levels of immunoglobulin G2 antibodies to Plasmodium falciparum merozoite antigens in Gabonese children

F Ntoumi , L Flori , Pi Mayengue , Dwm Maya , S Issifou et al.
Journal of Infectious Diseases, 2005, 192 (11), pp.1975-1980. ⟨10.1086/497611⟩
Article dans une revue hal-01595918 v1

TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso

L Flori , Nf Delahaye , Fa Iraqi , M Hernandez-Valladares , F Fumoux et al.
Genes and Immunity, 2005, 6 (6), pp.472-480
Article dans une revue hal-01595917 v1

TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso.

Laurence Flori , N.F. Delahaye , F.A. Iraqi , M. Hernandez-Valladares , F. Fumoux et al.
Genes and Immunity, 2005, 6, pp.472-480
Article dans une revue hal-02680051 v1

Influence of carriage of hemoglobin AS and the Fcg receptor IIa-R131 allele on levels of immunoglobulin G2 antibodies to plasmodium falciparum merozoite antigens in Gabonese children.

F. Ntoumi , Laurence Flori , P.I. Mayengue , D.W. Matondo Maya , S. Issifou et al.
Journal of Infectious Diseases, 2005, 192, pp.1975-1980
Article dans une revue hal-02676176 v1

Comparison of pathology in susceptible A/J and resistant C57BL/6J mice after infection with different sub-strains of Plasmodium chabaudi

M Hernandez-Valladares , J Naessens , S Nagda , Aj Musoke , Pascal Rihet et al.
Experimental Parasitology, 2004, 108 (3-4), pp.134-141
Article dans une revue hal-01595922 v1

Hemoglobin C is associated with reduced Plasmodium falciparum parasitemia and low risk of mild malaria attack

Pascal Rihet , L Flori , F Tall , As Traore , F Fumoux
Human Molecular Genetics, 2004, 13 (1), pp.1-6
Article dans une revue hal-01595920 v1

Mapping of a new quantitative trait locus for resistance to malaria in mice by a comparative mapping approach with human Chromosome 5q31-q33

M Hernandez-Valladares , Pascal Rihet , Ok Ole-Moiyoi , Fa Iraqi
Immunogenetics, 2004, 56 (2), pp.115-117
Article dans une revue hal-01595919 v1

Confirmation and dissection of QTL controlling resistance to malaria in mice

M Hernandez-Valladares , J Naessens , Jp Gibson , Aj Musoke , S Nagda et al.
Mammalian Genome, 2004, 15 (5), pp.390-398
Article dans une revue hal-01595921 v1

Linkage and association between Plasmodium falciparum blood infection levels and chromosome 5q31-q33

L Flori , B Kumulungui , C Aucan , C Esnault , As Traore et al.
Genes and Immunity, 2003, 4 (4), pp.265-268
Article dans une revue hal-01595924 v1

Linkage of mild malaria to the major histocompatibility complex in families living in Burkina Faso

L Flori , S Sawadogo , C Esnault , Nf Delahaye , F Fumoux et al.
Human Molecular Genetics, 2003, 12 (4), pp.375-378
Article dans une revue hal-01595923 v1

Familial correlation of immunoglobulin g subclass responses to Plasmodium falciparum antigens in Burkina Faso

C Aucan , Y Traore , F Fumoux , Pascal Rihet
Infection and Immunity, 2001, 69 (2), pp.996-1001
Article dans une revue hal-01595925 v1

Modification of P-selectin glycoprotein ligand-1 with a natural killer cell-restricted sulfated lactosamine creates an alternate ligand for L-selectin

P André , O Spertini , S Guia , Pascal Rihet , Francoise Dignat-George et al.
Proceedings of the National Academy of Sciences of the United States of America, 2000, 97 (7), pp.3400-3405. ⟨10.1073/pnas.97.7.340⟩
Article dans une revue hal-01595927 v1

High immunoglobulin G2 (IgG2) and low IgG4 levels are associated with human resistance to Plasmodium falciparum malaria

C Aucan , Y Traore , F Tall , B Nacro , T Traore-Leroux et al.
Infection and Immunity, 2000, 68 (3), pp.1252-1258
Article dans une revue hal-01595926 v1

[Analysis of the genetic factors controlling malarial infection in man].

Y Traore , Pascal Rihet , Thérèse Traore-Leroux , C Aucan , P Gazin et al.
Sante (Montrouge, France), 1999, 9 (1), pp.53-9
Article dans une revue hal-01595928 v1

Genetic dissection of Plasmodium falciparum blood infection levels and other complex traits related to human malaria infection.

Pascal Rihet , Y Traore , C Aucan , T Traore-Leroux , B Kumulungui et al.
Parassitologia, 1999, 41 (1-3), pp.83-7
Article dans une revue hal-01595929 v1

Human malaria: Segregation analysis of blood infection levels in a suburban area and a rural area in Burkina Faso

Pascal Rihet , L Abel , Y Traore , C Aucan , F Fumoux
Genetic Epidemiology, 1998, 15 (5), pp.435-450
Article dans une revue hal-01595932 v1

Malaria in humans: Plasmodium falciparum blood infection levels are linked to chromosome 5q31-q33

Pascal Rihet , Y Traore , L Abel , C Aucan , T Traore-Leroux et al.
American Journal of Human Genetics, 1998, 63 (2), pp.498-505
Article dans une revue hal-01595931 v1

RESISTANCE TO SCHISTOSOMA-MANSONI IN HUMANS - INFLUENCE OF THE IGE/IGG4 BALANCE AND IGG2 IN IMMUNITY TO REINFECTION AFTER CHEMOTHERAPY

Ce Demeure , Pascal Rihet , L Abel , M Ouattara , A Bourgois et al.
Journal of Infectious Diseases, 1993, 168 (4), pp.1000-1008
Article dans une revue hal-01595933 v1

FACTORS CONTROLLING RESISTANCE TO SCHISTOSOMIASIS IN ENDEMIC AREA

A Dessein , Pascal Rihet , C Demeure , P Couissinier , O Bacellar et al.
Médecine/Sciences, 1992, 8 (2), pp.108-118
Article dans une revue hal-01595938 v1

ENVIRONMENTAL, GENETIC AND IMMUNOLOGICAL FACTORS IN HUMAN RESISTANCE TO SCHISTOSOMA-MANSONI

A Prata , Aj Dessein , P Couissinier , C Demeure , Pascal Rihet et al.
Immunological Investigations, 1992, 21 (5), pp.423-453
Article dans une revue hal-01595935 v1

STRONG SERUM INHIBITION OF SPECIFIC IGE CORRELATED TO COMPETING IGG4, REVEALED BY A NEW METHODOLOGY IN SUBJECTS FROM A SCHISTOSOMA-MANSONI ENDEMIC AREA

Pascal Rihet , Ce Demeure , Aj Dessein , A Bourgois
European Journal of Immunology, 1992, 22 (8), pp.2063-2070
Article dans une revue hal-01595934 v1

EVIDENCE FOR AN ASSOCIATION BETWEEN HUMAN RESISTANCE TO SCHISTOSOMA-MANSONI AND HIGH ANTI-LARVAL IGE LEVELS

Pascal Rihet , Ce Demeure , A Bourgois , A Prata , Aj Dessein
European Journal of Immunology, 1991, 21 (11), pp.2679-2686
Article dans une revue hal-01595940 v1
Image document

122 - Temporal deletions of Nkx2-5 induce hypertrabeculation and progressive conduction defects and heart failure

M. Nguyen , C. Choquet , Pierre Sicard , F. Kober , I. Varlet et al.
Printemps de la Cardiologie : Recherche Fondamentale et Clinique, Apr 2017, Nantes, France. pp.208, ⟨10.1016/S1878-6480(17)30515-3⟩
Communication dans un congrès hal-01784720 v1