|
Report from the 28th Meeting on Toxinology, “Toxins: What’s up, Doc?”, Organized by the French Society of Toxinology on 28–29 November 2022
P. Marchot
,
Évelyne Benoit
,
Ziad Fajloun
,
Sylvie Diochot
Journal articles
hal-03978955v1
|
|
Patient-derived antibodies reveal the subcellular distribution and heterogeneous interactome of LGI1
Jorge Ramirez-Franco
,
Kévin Debreux
,
Johanna Extremet
,
Yves Maulet
,
Maya Belghazi
et al.
Journal articles
hal-03701887v1
|
|
Report from the 27th (Virtual) Meeting on Toxinology, “Toxins: Mr Hyde or Dr Jekyll?”, Organized by the French Society of Toxinology, 9–10 December 2021
Daniel Ladant
,
P. Marchot
,
Sylvie Diochot
,
Gilles Prévost
,
Michel Popoff
et al.
Journal articles
hal-03551958v1
|
|
Comparative mapping of selected structural determinants on the extracellular domains of cholinesterase-like cell-adhesion molecules.
Davide Comoletti
,
Laura Trobiani
,
Arnaud Chatonnet
,
Yves Bourne
,
P. Marchot
et al.
Journal articles
hal-03021748v1
|
|
The neuroligins and the synaptic pathway in Autism Spectrum Disorder.
Laura Trobiani
,
Maria Meringolo
,
Tamara Diamanti
,
Yves Bourne
,
P. Marchot
et al.
Journal articles
hal-03021773v1
|
|
The Ig-like domain of Punctin/MADD-4 is the primary determinant for interaction with the ectodomain of neuroligin NLG-1
Semeli Platsaki
,
Xin Zhou
,
Bérangère Pinan-Lucarré
,
Vincent Delauzun
,
Haijun Tu
et al.
Journal articles
hal-03021788v1
|
|
Report from the 26th Meeting on Toxinology, Bioengineering of Toxins, Organized by the French Society of Toxinology (SFET) and Held in Paris, France, 4-5 December 2019
P. Marchot
,
Sylvie Diochot
,
Michel R Popoff
,
Evelyne Benoit
Journal articles
hal-02441465v1
|
|
An evolutionary perspective on the first disulfide bond in members of the cholinesterase-carboxylesterase (COesterase) family: Possible outcomes for cholinesterase expression in prokaryotes
Arnaud Chatonnet
,
Xavier Brazzolotto
,
Thierry Hotelier
,
Nicolas Lenfant
,
P. Marchot
et al.
Journal articles
hal-02269496v1
|
|
Hot Spots for Protein Partnerships at the Surface of Cholinesterases and Related α/β Hydrolase Fold Proteins or Domains—A Structural Perspective
Yves Bourne
,
P. Marchot
Journal articles
hal-01802955v1
|
|
Cyclic imine toxins from dinoflagellates: a growing family of potent antagonists of the nicotinic acetylcholine receptors
Jordi Molgó
,
P. Marchot
,
Rómulo Aráoz
,
Evelyne Benoit
,
Bogdan I Iorga
et al.
Journal articles
hal-01661784v1
|
|
Preface: Cholinergic Mechanisms
Marco Prado
,
P. Marchot
,
Israel Silman
,
Marco A.M. Prado
Journal articles
hal-01802851v1
|
|
A Triad of Crystals Sheds Light on MDGA Interference with Neuroligation
Olivier Thoumine
,
P. Marchot
Journal articles
hal-01802853v1
|
|
Natural genomic amplification of cholinesterase genes in animals
Arnaud Chatonnet
,
Nicolas Lenfant
,
P. Marchot
,
Murray E. Selkirk
Journal articles
hal-01608096v1
|
|
The three-finger toxin fold: a multifunctional structural scaffold able to modulate cholinergic functions
Pascal Kessler
,
P. Marchot
,
Marcela Silva
,
Denis Servent
Journal articles
hal-01802811v1
|
|
Relationships of human alpha/beta hydrolase fold proteins and other organophosphate-interacting proteins
Nicolas Lenfant
,
Yves Bourne
,
P. Marchot
,
Arnaud Chatonnet
Journal articles
hal-01439103v1
|
|
Steric and Dynamic Parameters Influencing In Situ Cycloadditions to Form Triazole Inhibitors with Crystalline Acetylcholinesterase
Yves Bourne
,
K. Barry Sharpless
,
Palmer Taylor
,
P. Marchot
Journal articles
hal-01439081v1
|
|
Crystal Structure of Snake Venom Acetylcholinesterase in Complex with Inhibitory Antibody Fragment Fab410 Bound at the Peripheral Site EVIDENCE FOR OPEN AND CLOSED STATES OF A BACK DOOR CHANNEL
Yves Bourne
,
Ludovic Renault
,
P. Marchot
Journal articles
hal-01439005v1
|
|
Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal α7 from Muscle α12βγδ nAChRs.
Yves Bourne
,
Gerlind Sulzenbacher
,
Zoran Radić
,
Rómulo Aráoz
,
Morgane Reynaud
et al.
Journal articles
hal-01178822v1
|
|
The neuroligins and their neurexin ligands: from structure to function at the synapse
Yves Bourne
,
P. Marchot
Journal articles
hal-03270068v1
|
|
Editorial : Special Issue on "freshwater and marine toxins".
Evelyne Benoit
,
César Mattei
,
Julien Barbier
,
P. Marchot
,
Jordi Molgó
et al.
Journal articles
hal-01165542v1
|
|
Tracking the origin and divergence of cholinesterases and neuroligins: the evolution of synaptic proteins
Nicolas Lenfant
,
Thierry Hotelier
,
Yves Bourne
,
P. Marchot
,
Arnaud Chatonnet
et al.
Journal articles
hal-01190082v1
|
|
ESTHER, the database of the α/β-hydrolase fold superfamily of proteins: tools to explore diversity of functions
Nicolas Lenfant
,
Thierry Hotelier
,
Eric Velluet
,
Yves Bourne
,
P. Marchot
et al.
Journal articles
hal-01218998v1
|
|
Molecular Characterization of Monoclonal Antibodies that Inhibit Acetylcholinesterase by Targeting the Peripheral Site and Backdoor Region
Yves Bourne
,
Ludovic Renault
,
Sosthène Essono
,
Grégoire Mondielli
,
Patricia Lamourette
et al.
Journal articles
hal-01771534v1
|
|
Proteins with an alpha/beta hydrolase fold: Relationships between subfamilies in an ever-growing superfamily.
Nicolas Lenfant
,
Thierry Hotelier
,
Yves Bourne
,
P. Marchot
,
Arnaud Chatonnet
et al.
Journal articles
hal-01837554v1
|
|
Editorial : Special issue on "toxins: from threats to benefits".
Marie-France Martin-Eauclaire
,
Evelyne Benoit
,
P. Marchot
,
Julien Barbier
,
Jordi Molgó
et al.
Journal articles
hal-00919888v1
|
|
Hydrolase versus other functions of members of the alpha/beta-hydrolase fold superfamily of proteins.
P. Marchot
,
Arnaud Chatonnet
Journal articles
hal-00755664v1
|
|
Enzymatic activity and protein interactions in alpha/beta hydrolase fold proteins: moonlighting versus promiscuity.
P. Marchot
,
Arnaud Chatonnet
Journal articles
hal-00755665v1
|
|
Structural Insights into Antibody Sequestering and Neutralizing of Na+ Channel α-Type Modulator from Old World Scorpion Venom.
Igor P Fabrichny
,
Grégoire Mondielli
,
Sandrine Conrod
,
Marie-France Martin-Eauclaire
,
Yves Bourne
et al.
Journal articles
hal-00701162v1
|
|
Conformational remodeling of femtomolar inhibitor-acetylcholinesterase complexes in the crystalline state.
Yves Bourne
,
Zoran Radić
,
Palmer Taylor
,
P. Marchot
Journal articles
hal-00625332v1
|
|
Structure-function relationships of the alpha/beta-hydrolase fold domain of neuroligin: A comparison with acetylcholinesterase.
Philippe Leone
,
Davide Comoletti
,
Palmer Taylor
,
Yves Bourne
,
P. Marchot
et al.
Journal articles
hal-00482300v1
|
|
Structural insights into the exquisite selectivity of neurexin/neuroligin synaptic interactions.
Philippe Leone
,
Davide Comoletti
,
Géraldine Ferracci
,
Sandrine Conrod
,
Simon U Garcia
et al.
Journal articles
hal-00625337v1
|
|
Insecticide resistance through mutations in cholinesterases or carboxylesterases : data mining in the ESTHER database
Thierry Hotelier
,
Vincent Negre
,
P. Marchot
,
Arnaud Chatonnet
Journal articles
hal-02661971v1
|
|
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism
Yves Bourne
,
Zoran Radić
,
Rómulo Aráoz
,
Todd Talley
,
Evelyne Benoit
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (13), pp.6076-6081. ⟨10.1073/pnas.0912372107⟩
Journal articles
hal-03634913v1
|
|
Structural determinants in phycotoxins and AChBP conferring high affinity binding and nicotinic AChR antagonism.
Yves Bourne
,
Zoran Radic
,
Rómulo Aráoz
,
Todd T Talley
,
Evelyne Benoit
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (13), pp.6076-81. ⟨10.1073/pnas.0912372107⟩
Journal articles
hal-00464306v1
|
|
Structural determinants for interaction of partial agonists with acetylcholine binding protein and neuronal α7 nicotinic acetylcholine receptor
Ryan Hibbs
,
Gerlind Sulzenbacher
,
Jianxin Shi
,
Todd Talley
,
Sandrine Conrod
et al.
Journal articles
hal-01809973v1
|
|
Structural Analysis of the Synaptic Protein Neuroligin and Its β-Neurexin Complex: Determinants for Folding and Cell Adhesion
Igor Fabrichny
,
Philippe Leone
,
Gerlind Sulzenbacher
,
Davide Comoletti
,
Meghan Miller
et al.
Journal articles
hal-02989328v1
|
|
Substrate and product trafficking through the active center gorge of acetylcholinesterase analyzed by crystallography and equilibrium binding.
Yves Bourne
,
Zoran Radic
,
Gerlind Sulzenbacher
,
Esther Kim
,
Palmer Taylor
et al.
Journal articles
hal-00134313v1
|
|
Structural comparison of three crystalline complexes of a peptidic toxin with a synaptic acetylcholine recognition protein.
Yves Bourne
,
Scott B Hansen
,
Gerlind Sulzenbacher
,
Todd T Talley
,
Tom Huxford
et al.
Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.103-4
Journal articles
hal-00134316v1
|
|
Structural characterization of agonist and antagonist-bound acetylcholine-binding protein from Aplysia californica.
Scott B Hansen
,
Gerlind Sulzenbacher
,
Tom Huxford
,
P. Marchot
,
Yves Bourne
et al.
Journal of Molecular Neuroscience, 2006, 30 (1-2), pp.101-2
Journal articles
hal-00134314v1
|
|
A. niger protein “EstA”, perhaps a new electrotactin, defines a new class of fungal esterases within the α/β hydrolase fold superfamily
Yves Bourne
,
Alinda Hasper
,
Henri Chahinian
,
Ludovic Renault
,
Marianick Juin
et al.
Journal articles
hal-03263187v1
|
|
Structural insights into conformational flexibility at the peripheral site and within the active center gorge of AChE, Chem Biol Interact. 157-158, 159-65.
Yves Bourne
,
Z. Radic
,
Kolb H. C.
,
Sharpless K. B.
,
P. Taylor
et al.
Chemico-Biological Interactions, 2005, 157-158, pp.159-65
Journal articles
hal-00018799v1
|
|
Structural insights into AChE inhibition by monoclonal antibodies
Ludovic Renault
,
Sosthène Essono
,
Marianick Juin
,
Didier Boquet
,
Jacques Grassi
et al.
Journal articles
hal-03263196v1
|
|
Structures of Aplysia AChBP complexes with nicotinic agonists and antagonists reveal distinctive binding interfaces and conformations
Scott B Hansen
,
Gerlind Sulzenbacher
,
Tom Huxford
,
P. Marchot
,
Palmer Taylor
et al.
Journal articles
hal-03160548v1
|
|
Expression of the standard scorpion alpha-toxin AaH II and AaH II mutants leading to the identification of some key bioactive elements
C. Legros
,
B. Ceard
,
H. Vacher
,
P. Marchot
,
Bougis P. E.
et al.
BBA - Biochimica et Biophysica Acta, 2005, 1723, pp.91 99
Journal articles
hal-00021020v1
|
|
New friendly tools for users of ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins,
L. Renault
,
V. Negre
,
T. Hotelier
,
Xavier Cousin
,
P. Marchot
et al.
Chemico-Biological Interactions, 2005, 157-158, pp.339-43
Journal articles
hal-00018798v1
|
|
Crystal structure of a Cbtx-AChBP complex reveals essential interactions between snake alpha-neurotoxins and nicotinic receptors,
Yves Bourne
,
T. T. Talley
,
Hansen S. B.
,
P. Taylor
,
P. Marchot
et al.
EMBO Journal, 2005, 24, pp.1512-1522
Journal articles
hal-00021395v1
|
|
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
Y. Bourne
,
H. Kolb
,
Z. Radic
,
K. Sharpless
,
P. Taylor
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2004, 101 (6), pp.1449-1454. ⟨10.1073/pnas.0308206100⟩
Journal articles
hal-03263174v1
|
|
Aspergillus niger Protein EstA Defines a New Class of Fungal Esterases within the α/β Hydrolase Fold Superfamily of Proteins
Yves Bourne
,
Alinda A Hasper
,
Henri Chahinian
,
Marianick Juin
,
Leo H de Graaff
et al.
Journal articles
hal-03263177v1
|
|
ESTHER, the database of the alpha/beta-hydrolase fold superfamily of proteins
Thierry Hotelier
,
Ludovic Renault
,
Xavier Cousin
,
Vincent Negre
,
P. Marchot
et al.
Journal articles
hal-02679326v1
|
|
Structural insights into ligand interactions at the acetylcholinesterase peripheral anionic site
Yves Bourne
,
Palmer Taylor
,
Zoran Radic
,
P. Marchot
Journal articles
hal-03263169v1
|
|
Use of a purified and functional recombinant calcium-channel β4 subunit in surface-plasmon resonance studies
Sandrine Geib
,
Guillaume Sandoz
,
Kamel Mabrouk
,
Alessandra Matavel
,
P. Marchot
et al.
Journal articles
hal-03263160v1
|
|
Mechanism of Acetylcholinesterase Inhibition by Fasciculin: A 5-ns Molecular Dynamics Simulation
Kaihsu Tai
,
Tongye Shen
,
Richard Henchman
,
Yves Bourne
,
P. Marchot
et al.
Journal articles
hal-03263152v1
|
|
On the kaliotoxin and dendrotoxin binding sites on rat brain synaptosomes
N Tricaud
,
P. Marchot
,
M.F Martin-Eauclaire
Journal articles
hal-03262596v1
|
|
Immunocytochemical Localization and Crystal Structure of Human Frequenin (Neuronal Calcium Sensor 1)
Yves Bourne
,
Jens Dannenberg
,
Verena Pollmann
,
P. Marchot
,
Olaf Pongs
et al.
Journal articles
hal-03263149v1
|
|
Electron paramagnetic resonance reveals altered topography of the active center gorge of acetylcholinesterase after binding of fasciculin to the peripheral site
Marjeta Šentjurc
,
Slavko Pečar
,
Jure Stojan
,
P. Marchot
,
Zoran Radić
et al.
Journal articles
hal-03262546v1
|
|
L’interaction fasciculine-acétylcholinestérase
P. Marchot
Journal articles
hal-03363691v1
|
|
Crystal Structure of Mouse Acetylcholinesterase
Yves Bourne
,
Palmer Taylor
,
Pierre E Bougis
,
P. Marchot
Journal articles
hal-03262510v1
|
|
Conformational Flexibility of the Acetylcholinesterase Tetramer Suggested by X-ray Crystallography*
Yves Bourne
,
Jacques Grassi
,
Pierre E Bougis
,
P. Marchot
Journal of Biological Chemistry, 1999, 274 (43), pp.30370-30376
Journal articles
hal-03262571v1
|
|
Inhibition of mouse acetylcholinesterase by fasciculin: Crystal structure of the complex and mutagenesis of fasciculin
P. Marchot
,
Yves Bourne
,
Claudine Prowse
,
Pierre Bougis
,
Palmer Taylor
et al.
Journal articles
hal-03262468v1
|
|
Residues at the Subunit Interfaces of the Nicotinic Acetylcholine Receptor That Contribute to α-Conotoxin M1 Binding
Naoya Sugiyama
,
P. Marchot
,
Chiaki Kawanishi
,
Hitoshi Osaka
,
Brian Molles
et al.
Journal articles
hal-03262437v1
|
|
Toxins selective for subunit interfaces as probes of nicotinic acetylcholine receptor structure
Palmer Taylor
,
Hitoshi Osaka
,
Brian Molles
,
Naoya Sugiyama
,
P. Marchot
et al.
Journal articles
hal-03262491v1
|
|
Expression and Activity of Mutants of Fasciculin, a Peptidic Acetylcholinesterase Inhibitor from Mamba Venom*
P. Marchot
,
Claudine N Prowse
,
Joan Kanter
,
Shelley Camp
,
Elizabeth J Ackermann
et al.
Journal of Biological Chemistry, 1997, 272 (6), pp.3502-3510
Journal articles
hal-03262147v1
|
|
Soluble monomeric acetylcholinesterase from mouse: Expression, purification, and crystallization in complex with fasciculin
P. Marchot
,
Raimond B.G. Ravelli
,
Mia Raves
,
Yves Bourne
,
Daniel Vellom
et al.
Journal articles
hal-03262129v1
|
|
Structure of fasciculin 2 from green mamba snake venom: evidence for unusual loop flexibility
Marie-Hélène Le Du
,
P. Marchot
,
D. Housset
,
P. Bougis
,
J. Navaza
et al.
Journal articles
hal-03262107v1
|
|
Structural bases for the specificity of cholinesterase catalysis and inhibition
Palmer Taylor
,
Zoran Radic
,
Natilie Hosea
,
Shelley Camp
,
P. Marchot
et al.
Journal articles
hal-03262048v1
|
|
Afaacytin, an alphabeta-fibrinogenase from Cerastes cerastes (Horned Viper) Venom, Activates Purified Factor X and Induces Serotonin Release from Human Blood Platelets
Fatirna Laraba-Djebari
,
Marie-France Martin-Eauclaire
,
Gerard Mauco
,
P. Marchot
Journal articles
hal-03261962v1
|
|
Acetylcholinesterase Inhibition by Fasciculin: Crystal Structure of the Complex
Yves Bourne
,
Palmer Taylor
,
P. Marchot
Journal articles
hal-03262026v1
|
|
Theoretical analysis of the structure of the peptide fasciculin and its docking to acetylcholinesterase
Harald van den Born
,
Zoran Radić
,
P. Marchot
,
Palmer Taylor
,
Igor Tsigelny
et al.
Journal articles
hal-03261936v1
|
|
Binding of 125I-fasciculin to rat brain acetylcholinesterase. The complex still binds diisopropyl fluorophosphate
P. Marchot
,
Akila Khelif
,
Yong-Hua Ji
,
Pascal Mansuelle
,
Pierre E. Bougis
et al.
Journal of Biological Chemistry, 1993, 268 (17), pp.12458-12467
Journal articles
hal-03261921v1
|
|
1.9 A resolution structure of fasciculin 1, an anti-acetylcholinesterase toxin from green mamba snake venom
Marie-Hélène Le Du
,
P. Marchot
,
Pierre E Bougis
,
Juan-Carlos Fontecilla-Camps
Journal articles
hal-03261892v1
|
|
A fibrinogen-clotting serine proteinase from Cerastes cerastes (horned viper) venom with arginine-esterase and amidase activities. Purification, characterization and kinetic parameter determination
Fatima Laraba-Djebari
,
Marie-France Martin-Eauclaire
,
P. Marchot
Journal articles
hal-03261910v1
|
|
Neurotoxicité chez la souris de portions riches en cystéines des protéines Tat du virus visna et de VIH-1
I Gourdou
,
K Mabrouk
,
G Harkiss
,
P. Marchot
,
N Watt
et al.
Comptes rendus de l’Académie des sciences. Série III, Sciences de la vie, 1990, 311 (4), pp.149-55
Journal articles
hal-03363668v1
|
|
Homologues of a K+ channel blocker α-dendrotoxin: characterization of synaptosomal binding sites and their coupling to elevation of cytosolic free calcium concentration
Z.M. Muniz
,
G.R. Tibbs
,
P. Marchot
,
P. Bougis
,
D.G. Nicholls
et al.
Journal articles
hal-03261848v1
|
|
Crystals of fasciculin 2 from green mamba snake venom. Preparation and preliminary x-ray analysis
Marie Hélène Le Du
,
P. Marchot
,
Pierre E Bougis
,
Juan-C Fontecilla-Camps
Journal articles
hal-03261830v1
|
|
Selective distinction at equilibrium between the two alpha-neurotoxin binding sites of Torpedo acetylcholine receptor by microtitration
P. Marchot
,
Paule Frachon
,
Pierre Bougis
Journal articles
hal-03261788v1
|
|
Localization of the toxic site of Naja mossambica cardiotoxins: small synthetic peptides express an in vivo lethality
P. Marchot
,
P.E. Bougis
,
B. Ceard
,
J. van Rietschoten
,
H. Rochat
et al.
Journal articles
hal-03261771v1
|
|
Selective loss of binding sites for the iodinated alpha-neurotoxin I from Naja mossambica mossambica venom upon enzymatic deglycosylation of Torpedo electric organ membranes
Saadia Zeghloul
,
P. Marchot
,
Pierre Bougis
,
Catherine Ronin
Journal articles
hal-03261835v1
|
|
Monitoring the purification by high-performance liquid chromatography of cardiotoxins from Naja mossambica mossambica using phase-sensitive two-dimensional nuclear magnetic resonance
Gottfried Otting
,
P. Marchot
,
Pierre E Bougis
,
Hervé Rochat
,
Kurt Wüthrich
et al.
Journal articles
hal-03261768v1
|
|
In vivo synergy of cardiotoxin and phospholipase A2 from the elapid snake Naja mossambica mossambica
Pierre E Bougis
,
P. Marchot
,
Hervé Rochat
Journal articles
hal-03261744v1
|
|
Use of high performance liquid chromatography to demonstrate quantitative variation in components of venom from the scorpion Androctonus australis hector
M.F Martin
,
Hervé Rochat
,
P. Marchot
,
Pierre E Bougis
Journal articles
hal-03261750v1
|
|
Characterization of elapidae snake venom components using optimized reverse-phase high-performance liquid chromatographic conditions and screening assays for alpha-neurotoxin and phospholipase A2 activities
Pierre E Bougis
,
P. Marchot
,
Hervé Rochat
Journal articles
hal-03261741v1
|