Philippe Arnaud

49
Documents

Présentation

Depuis 01/2012- GReD, CNRS-UCA-INSERM,Clermont-Ferrand

2004-2011 IGMM CNRS UMR5535, Montpellier

2000-2003 Babraham Institute, Cambridge, UK

1996-2000 Biomove, Université Blaise Pascal, Clermont-Ferrand.

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Publications

Image document

Non-canonical imprinting, manifesting as post-fertilization placenta-specific parent-of-origin dependent methylation, is not conserved in humans

Dagne Daskeviciute , Louise Chappell-Maor , Becky Sainty , Philippe P. Arnaud , Isabel Iglesias-Platas et al.
Human Molecular Genetics, In press, ⟨10.1093/hmg/ddaf009⟩
Article dans une revue hal-04961461 v1
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Biallelic non-productive enhancer-promoter interactions precede imprinted expression of Kcnk9 during mouse neural commitment

Cecilia Rengifo Rojas , Jil Cercy , Sophie Perillous , Céline Gonthier-Guéret , Bertille Montibus et al.
Human Genetics and Genomics Advances, 2024, 5 (2), pp.100271. ⟨10.1016/j.xhgg.2024.100271⟩
Article dans une revue hal-04444966 v2
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Variable allelic expression of imprinted genes at the Peg13, Trappc9, Ago2 cluster in single neural cells

Michael Claxton , Antonius Plagge , Ralph Bernardo , Peng Zhou , Daniel M Messerschmidt et al.
Frontiers in Cell and Developmental Biology, 2022, 10, ⟨10.3389/fcell.2022.1022422⟩
Article dans une revue hal-03811612 v1
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The Long Non-Coding RNA HOXA-AS2 Promotes Proliferation of Glioma Stem Cells and Modulates Their Inflammation Pathway Mainly through Post-Transcriptional Regulation

Elisa Le Boiteux , Pierre-Olivier Guichet , Konstantin Masliantsev , Bertille Montibus , Catherine Vaurs-Barriere et al.
International Journal of Molecular Sciences, 2022, 23 (9), pp.4743. ⟨10.3390/ijms23094743⟩
Article dans une revue hal-03668886 v1
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Widespread overexpression from the four DNA hypermethylated HOX clusters in aggressive (IDHwt) glioma is associated with H3K27me3 depletion and alternative promoter usage

Elisa Le Boiteux , Franck Court , Pierre‐Olivier Guichet , Catherine Vaurs-Barrière , Isabelle Vaillant et al.
Molecular Oncology, 2021, ⟨10.1002/1878-0261.12944⟩
Article dans une revue hal-03172071 v1
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HOX gene cluster (de)regulation in brain: from neurodevelopment to malignant glial tumours

Céline S Gonçalves , Elisa Le Boiteux , Philippe P. Arnaud , Bruno Costa
Cellular and Molecular Life Sciences, 2020, ⟨10.1007/s00018-020-03508-9⟩
Article dans une revue hal-02570662 v1
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TET3 controls the expression of the H3K27me3 demethylase Kdm6b during neural commitment

Bertille Montibus , Jil Cercy , Tristan Bouschet , Amandine Charras , Stéphanie Maupetit-Méhouas et al.
Cellular and Molecular Life Sciences, 2020, 78 (2), pp.757-768. ⟨10.1007/s00018-020-03541-8⟩
Article dans une revue hal-02863871 v1
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Transcriptional alterations in glioma result primarily from DNA methylation independent mechanisms

Franck Court , Elisa Le Boiteux , Anne Fogli , Mélanie Müller-Barthélémy , Catherine Vaurs-Barrière et al.
Genome Research, 2019, 29 (10), pp.1605-1621. ⟨10.1101/gr.249219.119⟩
Article dans une revue hal-02304180 v2
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The long non-coding RNA HOTAIR is transcriptionally activated by HOXA9 and is an independent prognostic marker in patients with malignant glioma

Ana Xavier-Magalhães , Céline S Gonçalves , Tatiana Lourenço , Marta Pojo , Miguel Rocha et al.
Oncotarget, 2018, 9 (21), pp.15740 - 15756. ⟨10.18632/oncotarget.24597⟩
Article dans une revue hal-01917288 v1
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DNA methylation profiling reveals a pathological signature that contributes to transcriptional defects of CD34 + CD15 − cells in early chronic-phase chronic myeloid leukemia

Stéphanie Maupetit-Méhouas , Franck Court , Céline Bourgne , Agnès Guerci-Bresler , Pascale Cony-Makhoul et al.
Molecular Oncology, 2018, 12 (6), pp.814 - 829. ⟨10.1002/1878-0261.12191⟩
Article dans une revue hal-01917284 v1
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In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression

Tristan Bouschet , Emeric Dubois , Christelle Reynes , Satya Kota , Stéphanie Rialle et al.
Cerebral Cortex, 2017, ⟨10.1093/cercor/bhw102⟩
Article dans une revue hal-01788685 v1
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Detection of the alternative lengthening of telomeres pathway in malignant gliomas for improved molecular diagnosis

Anne Fogli , Marie-Véronique Demattei , Laetitia Corset , Catherine Vaurs-Barrière , E. Chautard et al.
Journal of Neuro-Oncology, 2017, 135 (2), pp.381-390. ⟨10.1007/s11060-017-2585-7⟩
Article dans une revue hal-01643036 v1
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CLIFinder: Identification of LINE-1 Chimeric Transcripts in RNA-seq data

Marie-Elisa Pinson , Romain Pogorelcnik , Franck Court , Philippe P. Arnaud , Catherine Vaurs-Barrière
Article dans une revue hal-01629422 v1
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An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic research

Franck Court , Philippe P. Arnaud
Oncotarget, 2017, 8, pp.4110 - 4124
Article dans une revue hal-01917297 v1
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Imprinting control regions (ICRs) are marked by mono-allelic bivalent chromatin when transcriptionally inactive

Stéphanie Maupetit-Méhouas , Bertille Montibus , David Nury , Chiharu Tayama , Michel M. Wassef et al.
Nucleic Acids Research, 2016, 44 (2), pp.621 - 635. ⟨10.1093/nar/gkv960⟩
Article dans une revue hal-01917293 v1

The tumoral A genotype of the MGMT rs34180180 single-nucleotide polymorphism in aggressive gliomas is associated with shorter patients’ survival

Anne Fogli , Emmanuel Chautard , Catherine Vaurs-Barrière , Bruno Pereira , Mélanie Müller-Barthélémy et al.
Carcinogenesis, 2016, 37 (2), pp.169 - 176. ⟨10.1093/carcin/bgv251⟩
Article dans une revue hal-01629349 v1
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Deep sequencing and de novo assembly of the mouse oocyte transcriptome define the contribution of transcription to the DNA methylation landscape

Lenka Veselovska , Sébastien Smallwood , Heba Saadeh , Kathleen R Stewart , Felix Krueger et al.
Genome Biology, 2015, 16, pp.209. ⟨10.1186/s13059-015-0769-z⟩
Article dans une revue hal-01917300 v1

ICR Noncoding RNA Expression Controls Imprinting and DNA Replication at the Dlk1-Dio3 Domain

Satya k. Kota , David Llères , Tristan Bouschet , Ryutaro Hirasawa , Alice Marchand et al.
Developmental Cell, 2014, 31 (1), pp.19 - 33. ⟨10.1016/j.devcel.2014.08.009⟩
Article dans une revue hal-01788720 v1
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Characterization of Novel Paternal ncRNAs at the Plagl1 Locus, Including Hymai, Predicted to Interact with Regulators of Active Chromatin

Isabel Iglesias-Platas , Alex Martin-Trujillo , David Cirillo , Franck Court , Amy Guillaumet-Adkins et al.
PLoS ONE, 2012, 7 (6), ⟨10.1371/journal.pone.0038907⟩
Article dans une revue hal-01934522 v1

Transcription and histone methylation changes correlate with imprint acquisition in male germ cells

Amandine Henckel , Karim Chebli , Satya Kota , Philippe P. Arnaud , Robert Feil
EMBO Journal, 2012, 31 (3), pp.606 - 615. ⟨10.1038/emboj.2011.425⟩
Article dans une revue hal-01934523 v1
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Synergic reprogramming of mammalian cells by combined exposure to mitotic Xenopus egg extracts and transcription factors

Olivier O. Ganier , Stéphane S. Bocquet , Isabelle I. Peiffer , Vincent V. Brochard , Philippe P. Arnaud et al.
Proceedings of the National Academy of Sciences of the United States of America, 2011, 108 (42), pp.17331-17336. ⟨10.1073/pnas.1100733108⟩
Article dans une revue hal-01000287 v1
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Human imprinted retrogenes exhibit non-canonical imprint chromatin signatures and reside in non-imprinted host genes

David Monk , Philippe P. Arnaud , Jennifer Frost , Andrew Wood , Michael Cowley et al.
Nucleic Acids Research, 2011, 39 (11), pp.4577 - 4586. ⟨10.1093/nar/gkq1230⟩
Article dans une revue hal-01934525 v1

Genomic imprinting in germ cells: imprints are under control

Philippe P. Arnaud
Reproduction [Cambridge], 2010, 140 (3), pp.411 - 423. ⟨10.1530/REP-10-0173⟩
Article dans une revue hal-01934528 v1
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Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment

O. Alder , F. Lavial , A. Helness , E. Brookes , S. Pinho et al.
Development (Cambridge, England), 2010, 137 (15), pp.2483--2492. ⟨10.1242/dev.048363⟩
Article dans une revue hal-02193451 v1

Genome-wide identification of new imprinted genes

A. Henckel , Philippe P. Arnaud
Briefings in Functional Genomics, 2010, 9 (4), pp.304--14. ⟨10.1093/bfgp/elq016⟩
Article dans une revue hal-02193464 v1

Genomic imprinting in germ cells: imprints are under control

Philippe P. Arnaud
Reproduction [Cambridge], 2010, 140 (3), pp.411--23. ⟨10.1530/REP-10-0173⟩
Article dans une revue hal-02193452 v1

Genome-wide identification of new imprinted genes

A. Henckel , Philippe P. Arnaud
Briefings in Functional Genomics and Proteomics, 2010, 9 (4), pp.304 - 314. ⟨10.1093/bfgp/elq016⟩
Article dans une revue hal-01934526 v1

Reciprocal imprinting of human GRB10 in placental trophoblast and brain: evolutionary conservation of reversed allelic expression

Philippe P. Arnaud , David Monk , Philip Arnaud , Jennifer Frost , Frank Hills et al.
Human Molecular Genetics, 2009, 18 (16), pp.3066 - 3074. ⟨10.1093/hmg/ddp248⟩
Article dans une revue hal-01934533 v1

Histone methylation is mechanistically linked to DNA methylation at imprinting control regions in mammals

Amandine Henckel , Kazuhiko Nakabayashi , Lionel A. Sanz , Robert Feil , Kenichiro Hata et al.
Human Molecular Genetics, 2009, 18 (18), pp.3375 - 3383. ⟨10.1093/hmg/ddp277⟩
Article dans une revue hal-01934530 v1

A mono-allelic bivalent chromatin domain controls tissue-specific imprinting at Grb10.

Lionel A. Sanz , Stormy Chamberlain , Jean-Charles Sabourin , Amandine Henckel , Terry Magnuson et al.
EMBO Journal, 2008, 27 (19), pp.2523-32. ⟨10.1038/emboj.2008.142⟩
Article dans une revue inserm-00349502 v1

Comparative analysis of human chromosome 7q21 and mouse proximal chromosome 6 reveals a placental-specific imprinted gene, TFPI2/Tfpi2, which requires EHMT2 and EED for allelic-silencing

D. Monk , A. Wagschal , Philippe P. Arnaud , P. Muller , L. Parker-Katiraee et al.
Genome Research, 2008, 18 (8), pp.1270 - 1281. ⟨10.1101/gr.077115.108⟩
Article dans une revue hal-01934535 v1
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Identification of the Imprinted KLF14 Transcription Factor Undergoing Human-Specific Accelerated Evolution

Layla Parker-Katiraee , Andrew R. Carson , Takahiro Yamada , Philippe P. Arnaud , Robert Feil et al.
PLoS Genetics, 2007, 3 (5), pp.e65. ⟨10.1371/journal.pgen.0030065⟩
Article dans une revue hal-01934543 v1

Chromatin Immunoprecipitation (ChIP) on Unfixed Chromatin from Cells and Tissues to Analyze Histone Modifications

Alexandre Wagschal , Katia Delaval , Maëlle Pannetier , Philippe P. Arnaud , Robert Feil
Cold Spring Harbor protocols, 2007, 2007 (12), pdb.prot4767 - pdb.prot4767. ⟨10.1101/pdb.prot4767⟩
Article dans une revue hal-01934545 v1

Early mouse embryo development: could epigenetics influence cell fate determination?

Amandine Henckel , Szabolcs Tóth , Philippe P. Arnaud
BioEssays, 2007, 29 (6), pp.520 - 524. ⟨10.1002/bies.20591⟩
Article dans une revue istex hal-01934539 v1

PCR-Based Analysis of Immunoprecipitated Chromatin

Alexandre Wagschal , Katia Delaval , Maëlle Pannetier , Philippe P. Arnaud , Robert Feil
Cold Spring Harbor protocols, 2007, 2007 (12), pdb.prot4768-pdb.prot4768. ⟨10.1101/pdb.prot4768⟩
Article dans une revue hal-02891751 v1

MEDEA Takes Control of Its Own Imprinting

Philippe P. Arnaud , Robert Feil
Cell, 2006, 124 (3), pp.468 - 470. ⟨10.1016/j.cell.2006.01.020⟩
Article dans une revue hal-01934551 v1

Stochastic imprinting in the progeny of Dnmt3L−/− females

Philippe P. Arnaud , Kenichiro Hata , Masahiro Kaneda , En Li , Hiroyuki Sasaki et al.
Human Molecular Genetics, 2006, 15 (4), pp.589 - 598. ⟨10.1093/hmg/ddi475⟩
Article dans une revue hal-01934553 v1

Imprinting of IGF2 P0 transcript and novel alternatively spliced INS-IGF2 isoforms show differences between mouse and human

M Monk , S Sanches , Philippe P. Arnaud , A Apostolidou , H Hills et al.
Human Molecular Genetics, 2006, 15 (8), pp.1259 - 1269. ⟨10.1093/hmg/ddl041⟩
Article dans une revue hal-01934550 v1

Limited evolutionary conservation of imprinting in the human placenta

R Monk , Philippe P. Arnaud , S. Apostolidou , F. Hills , G. Kelsey et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (17), pp.6623 - 6628. ⟨10.1073/pnas.0511031103⟩
Article dans une revue hal-01934548 v1

Epigenetic deregulation of genomic imprinting in human disorders and following assisted reproduction

Philippe P. Arnaud , Robert Feil
Birth Defects Research Part C: Embryo Today: Reviews, 2005, 75 (2), pp.81 - 97. ⟨10.1002/bdrc.20039⟩
Article dans une revue istex hal-01934555 v1
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Development of cyclodextrin microspheres for pulmonary drug delivery

Malika Skiba , Frédéric Bounoure , Cécile Barbot , Philippe P. Arnaud , Mohamed Skiba
Journal of Pharmacy and Pharmaceutical Sciences, 2005, 8 (3), pp.409-418
Article dans une revue hal-02279132 v1

Identification and properties of imprinted genes and their control elements

G Smith , Philippe P. Arnaud , G. Kelsey , R.J. Smith
Cytogenetic and Genome Research, 2004, 105 (2-4), pp.335 - 345. ⟨10.1159/000078206⟩
Article dans une revue hal-01934557 v1

Conserved methylation imprints in the human and mouse GRB10 genes with divergent allelic expression suggests differential reading of the same mark.

Philippe P. Arnaud , Philip Arnaud , David Monk , Megan Hitchins , Emma Gordon et al.
Human Molecular Genetics, 2003, pp.1005-19
Article dans une revue hal-01934563 v1

Imprinted methylation profiles for proximal mouse Chromosomes 11 and 7 as revealed by methylation-sensitive representational difference analysis

Philippe P. Arnaud , David Monk , Rachel Smith , Philip Arnaud , Michael Preece et al.
Mammalian Genome, 2003, 14 (12), pp.805 - 816. ⟨10.1007/s00335-003-2287-7⟩
Article dans une revue istex hal-01934559 v1

Epigenetic properties and identification of an imprint mark in the Nesp-Gnasxl domain of the mouse Gnas imprinted locus.

Candice Coombes , Philippe P. Arnaud , Emma Gordon , Wendy Dean , Elizabeth Coar et al.
Molecular and Cellular Biology, 2003, pp.5475-88. ⟨10.1128/MCB.23.16.5475-5488.2003⟩
Article dans une revue hal-01934561 v1

The mouse Zac1 locus: basis for imprinting and comparison with human ZAC.

Rachel Smith , Philippe P. Arnaud , Galia Konfortova , Wendy Dean , Colin Beechey et al.
Gene, 2002, pp.101-12
Article dans une revue hal-01934564 v1

Analysis of the SINE S1 Pol III promoter from Brassica; impact of methylation and influence of external sequences.

Philippe P. Arnaud , M Arnaud , Y Yukawa , L. Lavie , T Pélissier et al.
The Plant Journal, 2001, pp.295-305
Article dans une revue hal-01934570 v1

SINE Retroposons Can Be Used In Vivo as Nucleation Centers for De Novo Methylation

Philippe P. Arnaud , Chantal Goubely , Thierry Pélissier , Jean-Marc Deragon
Molecular and Cellular Biology, 2000, 20 (10), pp.3434-3441. ⟨10.1128/mcb.20.10.3434-3441.2000⟩
Article dans une revue hal-04821523 v1

Improved thermostability of the North American firefly luciferase: saturation mutagenesis at position 354.

J. White , J Squirrell , Philippe P. Arnaud , C Lowe , J Murray
Biochemical Journal, 1996, pp.343-50
Article dans une revue hal-01934577 v1