Regis BOBE

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Publications

SERCA3, ubiquitous but specific calcium pumps?

Maëliss Toth , Shaymaa Alhabib , Boris Manoury , Régis Bobe , Véronique Leblais

Cell Calcium, 2025, 132, pp.103079. ⟨10.1016/j.ceca.2025.103079⟩

Article dans une revue hal-05304354v1

Piezo1 gain of function induces a platelet preactivation state

Christilla Bachelot-Loza , Aurore Marchelli , Laurie Ruch , Divina El Hamaoui , Julien Demagny et al.

Journal of Thrombosis and Haemostasis, 2025, ⟨10.1016/j.jtha.2025.11.028⟩

Article dans une revue hal-05441209v1

The Protein Kinase A Inhibitor KT5720 Prevents Endothelial Dysfunctions Induced by High-Dose Irradiation

François-Xavier Boittin , Nathalie Guitard , Maeliss Toth , Diane Riccobono , Hélène Théry et al.

International Journal of Molecular Sciences, 2024, 25 (4), pp.2269. ⟨10.3390/ijms25042269⟩

Article dans une revue hal-05304377v1

Two-pore channels (TPCs) acts as a hub for excitation-contraction coupling, metabolism and cardiac hypertrophy signalling

Antoine de Zélicourt , Abdallah Fayssoil , Arnaud Mansart , Faouzi Zarrouki , Ahmed Karoui et al.

Cell Calcium, 2024, 117, pp.102839. ⟨10.1016/j.ceca.2023.102839⟩

Article dans une revue hal-04409238v1

Niemann-Pick C1 protein regulates platelet membrane–associated calcium ion signaling in thrombo-occlusive diseases in mice

Mailin-Christin Manke , Anna Roslan , Britta Walker , Patrick Münzer , Ferdinand Kollotzek et al.

Journal of Thrombosis and Haemostasis, 2023, 21 (7), pp.1957-1966. ⟨10.1016/j.jtha.2023.03.038⟩

Article dans une revue hal-04453749v1

ADP receptor P2Y12 is the capstone of the cross-talk between Ca 2+ mobilization pathways dependent on ATPases SERCA3 and SERCA2b in platelet

Miao Feng , Béatrice Hechler , Frédéric Adam , Christian Gachet , Anita Eckly et al.

Research and Practice in Thrombosis and Haemostasis, In press

Article dans une revue (data paper) hal-03930689v1

The immunosuppressant drug Cyclosporin A aggravates irradiation effects in endothelial cells

François-Xavier Boittin , Kathia Beddek , Hélène Thery , Jérome Pateux , Guillaume Cosler et al.

Biochemical and Biophysical Research Communications, 2022, 602, pp.127-134. ⟨10.1016/j.bbrc.2022.02.096⟩

Article dans une revue hal-04453742v1

Endoglin Is an Endothelial Housekeeper against Inflammation: Insight in ECFC-Related Permeability through LIMK/Cofilin Pathway

Elisa Rossi , Alexandre Kauskot , François Saller , Elisa Frezza , Sonia Poirault-Chassac et al.

International Journal of Molecular Sciences, 2021, 22 (16), pp.8837. ⟨10.3390/ijms22168837⟩

Article dans une revue hal-03388849v1

SERCA3 calcium pump: discovery of a new calcium signalling pathway that triggers platelet activation

Miao Feng , Jean‐philippe Rosa , Regis Bobe

Revue Francophone d'Hémostase et Thrombose, 2021, 3 (1), pp.41-6

Article dans une revue hal-04453801v1

TRPV4 channel activation induces the transition of venous and arterial endothelial cells toward a pro‐inflammatory phenotype

Kathia Beddek , Florent Raffin , Delphine Borgel , François Saller , Diane Riccobono et al.

Physiological Reports, 2021, 9 (3), ⟨10.14814/phy2.14613⟩

Article dans une revue hal-04453732v1

NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation.

Miao Feng , Ziane Elaïb , Delphine Borgel , Cécile Denis , Frédéric Adam et al.

Circulation Research, 2020, 127 (7), pp.e166-e183. ⟨10.1161/CIRCRESAHA.119.316090⟩

Article dans une revue inserm-02948394v1

Platelet Functions are Decreased in Obesity and Restored after Weight Loss: Evidence for a Role of the SERCA3-Dependent ADP Secretion Pathway

Ziane Elaïb , Jose Lopez , Muriel Coupaye , Kevin Zuber , Yann Becker et al.

Thrombosis and Haemostasis, 2019, 119 (03), pp.384-396. ⟨10.1055/s-0038-1677033⟩

Article dans une revue hal-04453727v1

Filamin A Modulates Store-Operated Ca 2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)–Orai1 Association in Human Platelets

Jose Lopez , Letizia Albarrán , Isaac Jardín , Jose Sanchez-Collado , Pedro Redondo et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2018, 38 (2), pp.386-397. ⟨10.1161/ATVBAHA.117.310139⟩

Article dans une revue hal-04457054v1

Dominant negative Ras (DN Ras) attenuates pathological ventricular remodeling in pressure overload cardiac hypertrophy

Manuel Ramos-Kuri , Kleopatra Rapti , Hind Mehel , Shihong Zhang , Perundurai S Dhandapany et al.

Biochimica et Biophysica Acta - Molecular Cell Research, 2015, 1853 (11), pp.2870-2884. ⟨10.1016/j.bbamcr.2015.08.006⟩

Article dans une revue hal-02610567v1

Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis

Larissa Lipskaia , Zela Keuylian , Karl Blirando , Nathalie Mougenot , Adeline Jacquet et al.

Biochimica et Biophysica Acta - Molecular Cell Research, 2014, 1843 (11), pp.2705-2718. ⟨10.1016/j.bbamcr.2014.08.002⟩

Article dans une revue hal-01545429v1

Crucial Role for Endoplasmic Reticulum Stress During Megakaryocyte Maturation

Jose Lopez , Alberta Palazzo , Chiraz Chaabane , Letizia Albarran , Evelyne Polidano et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2013, 33 (12), pp.2750-2758. ⟨10.1161/ATVBAHA.113.302184⟩

Article dans une revue hal-04472255v1

Le récepteur PAR4 initie la voie SERCA3/NAADP qui potentialise l'activation des plaquettes en réponse à la thrombine.

Miao Feng , Frédéric Adam , Alexandre Kauskot , Cécile Denis , Marijke Bryckaert et al.

Congrès Francais d'Hémostase, May 2023, Saint malo, France

Poster de conférence hal-04455436v1

The immunosuppressant drug Cyclosporin A aggravates irradiation effects in endothelial cells

François-Xavier Boittin , Kathia Beddek , Hélène Thery , Jérome Pateux , Guillaume Cosler et al.

CRBNE Research & Innovation conference, May 2022, Lille, France

Poster de conférence hal-04455715v1

NAADP/SERCA3-Dependent Ca2+ Stores Pathway Specifically Controls Early Autocrine ADP Secretion Potentiating Platelet Activation

Miao Feng , Ziane Elaib , Delphine Borgel , Cécile Denis , Frederic Adam et al.

Virtual Congress of the International Society on Thrombosis and Haemostasis, Jul 2020, Milan (Virtual), Italy. Res. Pract. Thromb. Haemost, 4 (Suppl. 1), pp.Abstract PB1745, 2020

Poster de conférence hal-04501065v1

Ca2+ release from Sarco/Endoplamic Reticulum Ca2+-ATPase 3 (SERCA3) controlled stores is involved in endothelial permeability and inflammatory response.

Kathia Beddek , Frédéric Adam , Francois Saller , Delphine Borgel , Regis Bobe

ISTH 2020, Jul 2020, Virtual conference, France

Poster de conférence hal-04455301v1

NAADP/SERCA3-dependent Ca2+ stores pathway specifically controls early autocrine ADP secretion potentiating platelet activation.

Miao Feng , Ziane Elaib , Delphine Borgel , Cécile V. Denis , Frédéric Adam et al.

ISTH 2020, Jul 2020, Virtual congress, France

Poster de conférence hal-04455286v1

ROLE OF THE SERCA3/NAADP SIGNALING IN THE CARDIOVASCULAR SYSTEM

Miao Feng , Antoine de Zélicourt , Justine Page , José‐manuel Cancela , Sabine de La Porte et al.

Huitième colloque du LabEx Lermit, Nov 2019, Gif-sur-Yvette, France

Poster de conférence hal-04455220v1

ROLE OF THE SERCA3/NAADP SIGNALING IN THE CARDIOVASCULAR SYSTEM

Miao Feng , Antoine de Zélicourt , Justine Page , José-Manuel Cancela , Sabine de La Porte et al.

Huitième colloque du LabEx Lermit, Nov 2019, Gif-sur-Yvette, France

Poster de conférence hal-04519880v1

Specific mobilization of SERCA3-dependent Ca2+ stores by NAADP regulates platelet activity through ADP secretion.

Ziane Elaib , Miao Feng , Frédéric Adam , Marijke Bryckaert , Jean‐philippe Rosa et al.

15th International Meeting of the European Calcium Society, Sep 2018, Hambourg (Germany), Germany

Poster de conférence hal-04455185v1

Réserves de calcium et fonctions plaquettaires

Regis Bobe

9eme rencontre du CFPM, May 2022, Bordeaux (France), France

Communication dans un congrès hal-04455403v1

La diminution de l’activité des pompes à calcium SERCA3 permet la réduction de la réponse inflammatoire.

Kathia Beddek , Frédéric Adam , Francois Saller , Delphine Borgel , Regis Bobe

40eme congres de la SFH 2020, Sep 2020, Paris, France

Communication dans un congrès hal-04455333v1

L’activation des canaux TRPV4 induit la transition des cellules endothéliales veineuses ou artérielles vers un phénotype pro-inflammatoire.

Kathia Beddek , Florent Raffin , Francois Saller , Delphine Borgel , Diane Riccobono et al.

40eme congres de la SFH, Sep 2020, Paris, France

Communication dans un congrès hal-04455362v1

L'ADP sécrétée par la voie de signalisation calcique plaquettaire NAADP/SERCA3 active spécifiquement le récepteur purinergique P2Y12 et pas P2Y1

Miao Feng , Cécile Denis , Regis Bobe , Jean‐philippe Rosa

8ème rencontre Club français des plaquettes et des mégacayocytes, Nov 2020, plateforme zoom, France

Communication dans un congrès hal-04455261v1

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