Rodolphe Thiébaut

255
Documents

Présentation

Position title

· Professor (PUPH) of Public Health, Bordeaux University

· **Director the INSERM/INRIA team SISTM: Statistics in Systems Biology and Translational Medicine (Since 2013, 25 people, http://www.bordeaux-population-health.center/en/teams/statistics-in-systems-biology-and-translationnal-medicine-sistm/))

· Director of the Bioinformatics/Biostatistics Division of the Vaccine Research Institute (VRI, http://vaccine-research-institute.fr/en/)

· Director of the Department of research in Public Health at the Bordeaux University (Since 2019) and Deputy Director of the INSERM Research Centre U1219 (Since 2008, formally U897, 460 people, http://www.bordeaux-population-health.center/en/)

· Director of the Medical Information Department at Bordeaux Hospital (Since 2019)

· Director of the Digital Public Health Graduate School (Since 2018)

· Member of the INSERM scientific committee (Since 2017)

Education

Institution and location

Degree

Year

Field of study

Bordeaux University

M.D.

2000

Public Health

Bordeaux University

Ph.D.

2002

Biostatistics

Bordeaux University

Diploma for PhD student supervision (HDR)

2004

Previous Positions

==================

ü 2013-2019: Director of the Bordeaux Hospital Clinical Trial Unit (Since 2013, 25 people, http://usmr.isped.u-bordeaux2.fr)

ü 2012-2014: Deputy director of the Institute of Research in Public Health (IReSP http://www.iresp.net/)

ü 2009-2014: Deputy Director of the Bordeaux School of Public Health (ISPED) for Research (www.isped.u-bordeaux.fr)

ü 2002-2013: Researcher (CR2, CR1) and Research Director (DR2) at the French Institute for Health and Medical Research (INSERM), Research Centre U897 “Epidemiology and Biostatistics” (Tenure Track since 2002)

Teaching activities

ü Director of the Master in Science “Public Health Data Science” (Since 2018)

ü Responsible of the modelling unit for medical students and of the mathematics unit for medicine/science cursus

ü Analysis of longitudinal data for Master Students (Since 2000, 30 hours/year) and Summer School

Publications

Publications

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Long-term cellular immunity of vaccines for Zaire Ebola Virus Diseases

Aurélie Wiedemann , Edouard Lhomme , Mélanie Huchon , Emile Foucat , Marion Bérerd-Camara et al.
Nature Communications, 2024, 15 (1), pp.7666. ⟨10.1038/s41467-024-51453-z⟩
Article dans une revue hal-04707176 v1
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Rapid access to innovative medicinal products while ensuring relevant health technology assessment. Position of the French National Authority for Health

Antoine Vanier , Judith Fernandez , Sophie Kelley , Lise Alter , Patrick Semenzato et al.
BMJ Evidence-Based Medicine, 2024, 29 (1), pp.1-5. ⟨10.1136/bmjebm-2022-112091⟩
Article dans une revue hal-04056273 v1
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Helminth exposure and immune response to the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccine regimen

Houreratou Barry , Edouard Lhomme , Mathieu Surenaud , Moumini Nouctara , Cynthia Robinson et al.
PLoS Neglected Tropical Diseases, 2024, 18 (4), pp.e0011500. ⟨10.1371/journal.pntd.0011500⟩
Article dans une revue hal-04611372 v1

Fréchet random forests for metric space valued regression with non Euclidean predictors

Louis Capitaine , Jérémie Bigot , Rodolphe Thiébaut , Robin Genuer
Journal of Machine Learning Research, 2024, 25 (355), pp.1-41
Article dans une revue hal-03066146 v1
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Post-clustering difference testing: valid inference and practical considerations

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum
Computational Statistics and Data Analysis, 2024, 193, pp.107916. ⟨10.1016/j.csda.2023.107916⟩
Article dans une revue hal-03889565 v1
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Association between humoral serological markers levels and risk of SARS-CoV-2 infection after the primary COVID-19 vaccine course among ANRS0001S COV-POPART cohort participants

Mathieu Chalouni , Paul Loubet , Edouard Lhomme , Laetitia Ninove , Benoit Barrou et al.
BMC Infectious Diseases, 2024, 24 (1), pp.1049. ⟨10.1186/s12879-024-09861-5⟩
Article dans une revue hal-04724620 v1
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Evaluation of waning of IgG antibody responses after rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccines: a modelling study from the PREVAC randomized trial

Simon Valayer , Marie Alexandre , Mélanie Prague , Abdoul Habib Beavogui , Seydou Doumbia et al.
Emerging microbes & infections, 2024, Online ahead of print. ⟨10.1080/22221751.2024.2432353⟩
Article dans une revue hal-04817450 v1
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Definition of Virological Endpoints Improving the Design of HIV Cure Strategies Using Analytical Antiretroviral Treatment Interruption

Marie Alexandre , Mélanie Prague , Edouard Lhomme , Jean-Daniel Lelièvre , Linda Wittkop et al.
Clinical Infectious Diseases, 2024, 79 (6), pp.1447-1457. ⟨10.1093/cid/ciae235⟩
Article dans une revue hal-04843977 v1
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Estimating the population effectiveness of interventions against COVID-19 in France: A modelling study

Iris Ganser , David L Buckeridge , Jane Heffernan , Mélanie Prague , Rodolphe Thiébaut
Epidemics, 2024, 46, pp.100744. ⟨10.1016/j.epidem.2024.100744⟩
Article dans une revue hal-04505758 v1

ChatGPT et au-delà avec l’intelligence artificielle en santé : des leçons à tirer

Rodolphe Thiébaut , Boris P. Hejblum , Fleur Mougin , Christophe Tzourio , Laura Richert
Revue du Rhumatisme, 2024, 91 (1), pp.12-15. ⟨10.1016/j.rhum.2023.07.007⟩
Article dans une revue hal-04466670 v1
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Redefining pandemic preparedness: Multidisciplinary insights from the CERP modelling workshop in infectious diseases, workshop report

Marta Nunes , Edward Thommes , Holger Fröhlich , Antoine Flahault , Julien Arino et al.
Infectious Disease Modelling, 2024, 9 (2), pp.501-518. ⟨10.1016/j.idm.2024.02.008⟩
Article dans une revue hal-04551033 v1

Safety and immunogenicity of CD40.HIVRI.Env, a dendritic cell-based HIV vaccine, in healthy HIV-uninfected adults: a first-in-human randomized, placebo-controlled, dose-escalation study (ANRS VRI06)

Yves Lévy , Yves Lévy , Christiane Moog , Christiane Moog , Aurélie Wiedemann et al.
EClinicalMedicine, 2024, 77 (8), pp.102845. ⟨10.1016/j.eclinm.2024.102845⟩
Article dans une revue hal-04832417 v1
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Neglecting normalization impact in semi-synthetic RNA-seq data simulation generates artificial false positives

Boris Hejblum , Kalidou Ba , Rodolphe Thiébaut , Denis Agniel
Genome Biology, 2024, 25 (1), pp.281. ⟨10.1101/2022.05.10.490529⟩
Article dans une revue hal-03908246 v1
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Clonal succession after prolonged antiretroviral therapy rejuvenates CD8<sup>+</sup> T cell responses against HIV-1

Eoghann White , Laura Papagno , Assia Samri , Kenji Sugata , Boris P. Hejblum et al.
Nature Immunology, 2024, 25 (9), pp.1555-1564. ⟨10.1038/s41590-024-01931-9⟩
Article dans une revue hal-04703528 v1
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A vaccine targeting antigen-presenting cells through CD40 induces protective immunity against Nipah disease

Yadira Pastor , Olivier Reynard , Mathieu Iampietro , Mathieu Surenaud , Florence Picard et al.
Cell Reports Medicine, 2024, 5 (3), pp.101467. ⟨10.1016/j.xcrm.2024.101467⟩
Article dans une revue hal-04569963 v1
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Impact of non-pharmaceutical interventions, weather, vaccination, and variants on COVID-19 transmission across departments in France

Juliette Paireau , Marie-Laure Charpignon , Sophie Larrieu , Clémentine Calba , Nathanaël Hozé et al.
BMC Infectious Diseases, 2023, 23 (190), ⟨10.1186/s12879-023-08106-1⟩
Article dans une revue hal-03791761 v2
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On the Choice of Longitudinal Models for the Analysis of Antitumor Efficacy in Mouse Clinical Trials of Patient-derived Xenograft Models

Hélène Savel , Sandrine Barbier , Cécile Proust-Lima , Virginie Rondeau , Rodolphe Thiébaut et al.
Cancer Research Communications, 2023, 3 (1), pp.140-147. ⟨10.1158/2767-9764.CRC-22-0238⟩
Article dans une revue hal-04403048 v1
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Parameter estimation in nonlinear mixed effect models based on ordinary differential equations: An optimal control approach

Quentin Clairon , Chloé Pasin , Irene Balelli , Rodolphe Thiébaut , Mélanie Prague
Computational Statistics, 2023
Article dans une revue hal-03335826 v2
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Assessment of circulating blood lymphocytes in adult patients on rituximab to treat immune thrombocytopenia: Circulating number of NK cells is associated with the response at 6 months.

Etienne Rivière , Rodolphe Thiébaut , Estibaliz Lazaro , Alexandre Guy , Chloé James et al.
British Journal of Haematology, In press, ⟨10.1111/bjh.18818⟩
Article dans une revue hal-04095049 v1
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ChatGPT and beyond with artificial intelligence (AI) in health: Lessons to be learned.

Rodolphe Thiebaut , Boris P. Hejblum , Fleur Mougin , Christophe Tzourio , Laura Richert
Joint Bone Spine, 2023, 90 (5), pp.105607. ⟨10.1016/j.jbspin.2023.105607⟩
Article dans une revue hal-04236822 v1
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Safety and immunogenicity of the two-dose heterologous Ad26.ZEBOV and MVA-BN-Filo Ebola vaccine regimen in infants: a phase 2, randomised, double-blind, active-controlled trial in Guinea and Sierra Leone

Edward Man-Lik Choi , Boris Lacarra , Muhammed O Afolabi , Boni Maxime Ale , Frank Baiden et al.
The Lancet global health, 2023, 11 (11), pp.e1743-e1752. ⟨10.1016/S2214-109X(23)00410-2⟩
Article dans une revue hal-04384862 v1
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Using Population Based Kalman Estimator to Model COVID-19 Epidemic in France: Estimating the Effects of Non-Pharmaceutical Interventions on the Dynamics of Epidemic

Annabelle Collin , Boris P. Hejblum , Carole Vignals , Laurent Lehot , Rodolphe Thiébaut et al.
The international journal of biostatistics, In press, ⟨10.1515/ijb-2022-0087⟩
Article dans une revue hal-04151651 v1
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Neutrophil Activation and Immune Thrombosis Profiles Persist in Convalescent COVID-19

Hakim Hocini , Aurélie Wiedemann , Fabiola Blengio , Cécile Lefebvre , Minerva Cervantes-Gonzalez et al.
Journal of Clinical Immunology, 2023, 43 (5), pp.882-893. ⟨10.1007/s10875-023-01459-x⟩
Article dans une revue hal-04373844 v1
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Doubly-robust evaluation of high-dimensional surrogate markers

Denis Agniel , Boris Hejblum , Rodolphe Thiébaut , Layla Parast
Biostatistics, 2023, 24 (4), pp.985-999. ⟨10.1093/biostatistics/kxac020⟩
Article dans une revue hal-03100499 v1
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Development and external validation of a prediction model for the transition from mild to moderate or severe form of COVID-19

Maéva Zysman , Julien Asselineau , Olivier Saut , Eric Frison , Mathilde Oranger et al.
European Radiology, 2023, 33, pp.9262-9274. ⟨10.1007/s00330-023-09759-x⟩
Article dans une revue hal-04153209 v1
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Prediction of long-term humoral response induced by the two-dose heterologous Ad26.ZEBOV, MVA-BN-Filo vaccine against Ebola

Marie Alexandre , Mélanie Prague , Chelsea Mclean , Viki Bockstal , Macaya Douoguih et al.
NPJ vaccines, 2023, 8 (174), ⟨10.1038/s41541-023-00767-y⟩
Article dans une revue hal-04226696 v2
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Identification of early gene expression profiles associated with long-lasting antibody responses to the Ebola vaccine Ad26.ZEBOV/MVA-BN-Filo

Fabiola Blengio , Hakim Hocini , Laura Richert , Cécile Lefebvre , Melany Durand et al.
Cell Reports, 2023, 42 (9), pp.113101. ⟨10.1016/j.celrep.2023.113101⟩
Article dans une revue hal-04273901 v1
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Modeling the evolution of the neutralizing antibody response against SARS-CoV-2 variants after several administrations of Bnt162b2

Quentin Clairon , Mélanie Prague , Delphine Planas , Timothée Bruel , Laurent Hocqueloux et al.
PLoS Computational Biology, 2023, 19 (8), pp.e1011282. ⟨10.1371/journal.pcbi.1011282⟩
Article dans une revue hal-03946556 v1
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Evaluating the Use of Generalized Dynamic Weighted Ordinary Least Squares for Individualized Hiv Treatment Strategies

Larry Dong , Erica E. M. Moodie , Laura Villain , Rodolphe Thiébaut
Annals of Applied Statistics, 2023, 17 (3), pp.2432-2451. ⟨10.1214/22-aoas1726⟩
Article dans une revue hal-04344321 v1

The benefit of augmenting open data with clinical data-warehouse EHR for forecasting SARS-CoV-2 hospitalizations in Bordeaux area, France

Thomas Ferté , Vianney Jouhet , Romain Griffier , Boris Hejblum , Rodolphe Thiébaut
JAMIA open, 2022, 5 (4), ⟨10.1093/jamiaopen/ooac086⟩
Article dans une revue hal-03908260 v1

Global Variations in Event-Based Surveillance for Disease Outbreak Detection: Time Series Analysis

Iris Ganser , Rodolphe Thiébaut , David Buckeridge
JMIR Public Health and Surveillance, 2022, 8 (10), pp.e36211. ⟨10.2196/36211⟩
Article dans une revue hal-03919665 v1

Incidence of cytomegalovirus infection in seropositive kidney transplant recipients treated with everolimus: A randomized, open‐label, multicenter phase 4 trial

Hannah Kaminski , Nassim Kamar , Olivier Thaunat , Nicolas Bouvier , Sophie Caillard et al.
American Journal of Transplantation, 2022, 22 (5), pp.1430-1441. ⟨10.1111/ajt.16946⟩
Article dans une revue hal-03848627 v1
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Inhaled ciclesonide for outpatient treatment of COVID-19 in adults at risk of adverse outcomes: a randomised controlled trial (COVERAGE)

Alexandre Duvignaud , Edouard Lhomme , Racha Onaisi , Rémi Sitta , Ambre Gelley et al.
Clinical Microbiology and Infection, 2022, 28 (7), pp.1010-1016. ⟨10.1016/j.cmi.2022.02.031⟩
Article dans une revue hal-03690132 v1
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Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

Marie Alexandre , Romain Marlin , Mélanie Prague , Séverin Coleon , Nidhal Kahlaoui et al.
eLife, 2022, 11, pp.e75427. ⟨10.7554/eLife.75427⟩
Article dans une revue hal-03482728 v2
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Design, immunogenicity, and efficacy of a pan-sarbecovirus dendritic-cell targeting vaccine

Séverin Coléon , Aurélie Wiedemann , Mathieu Surénaud , Christine Lacabaratz , Sophie Hue et al.
EBioMedicine, 2022, 80, pp.104062. ⟨10.1016/j.ebiom.2022.104062⟩
Article dans une revue hal-03692817 v1
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Modelling the response to vaccine in non-human primates to define SARS-CoV-2 mechanistic correlates of protection

Marie Alexandre , Romain Marlin , Mélanie Prague , Severin Coleon , Nidhal Kahlaoui et al.
eLife, 2022, 11, ⟨10.7554/elife.75427⟩
Article dans une revue hal-04510052 v1
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The respiratory microbiota alpha-diversity in chronic lung diseases: first systematic review and meta-analysis

Marta Avalos , Clémence Métayer , Thibaud Alin , Rodolphe Thiébaut , Raphaël Enaud et al.
Respiratory Research, 2022, 23 (214), ⟨10.1186/s12931-022-02132-4⟩
Article dans une revue hal-03762542 v1
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Enriching single-arm clinical trials with external controls: possibilities and pitfalls

Jérôme Lambert , Etienne Lengliné , Raphaël Porcher , Rodolphe Thiébaut , Sarah Zohar et al.
Blood Advances, In press, ⟨10.1182/bloodadvances.2022009167⟩
Article dans une revue hal-03914596 v1
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Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in children and adolescents in Africa: A randomised, placebo-controlled, multicentre Phase II clinical trial

Zacchaeus Anywaine , Houreratou Barry , Omu Anzala , Gaudensia Mutua , Sodiomon Sirima et al.
PLoS Medicine, 2022, 19 (1), pp.e1003865. ⟨10.1371/journal.pmed.1003865⟩
Article dans une revue hal-03690128 v1
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NK Cell Subset Redistribution and Antibody Dependent Activation after Ebola Vaccination in Africans

Helen R Wagstaffe , Omu Anzala , Hannah Kibuuka , Zacchaeus Anywaine , Sodiomon B Sirima et al.
Vaccines, 2022, 10 (6), pp.884. ⟨10.3390/vaccines10060884⟩
Article dans une revue hal-04418906 v1

Within-host models of SARS-CoV-2: What can it teach us on the biological factors driving virus pathogenesis and transmission?

Mélanie Prague , Marie Alexandre , Rodolphe Thiébaut , Jérémie Guedj
Anaesthesia Critical Care & Pain Medicine, 2022, 41 (2), pp.101055. ⟨10.1016/j.accpm.2022.101055⟩
Article dans une revue hal-03691907 v1
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Data-Driven Sparse Partial Least Squares

Hadrien Lorenzo , Olivier Cloarec , Rodolphe Thiébaut , Jérôme Saracco
Statistical Analysis and Data Mining, 2022, 15 (2), pp.264-282. ⟨10.1002/sam.11558⟩
Article dans une revue hal-03368956 v1

Incidence of cytomegalovirus infection in seropositive kidney transplant recipients treated with everolimus: A randomized, open‐label, multicenter phase 4 trial

Hannah Kaminski , Nassim Kamar , Olivier Thaunat , Nicolas Bouvier , Sophie Caillard et al.
American Journal of Transplantation, 2022, ⟨10.1111/ajt.16946⟩
Article dans une revue hal-03605036 v1

High temporal resolution transcriptomic profiling delineates distinct patterns of interferon response following Covid-19 mRNA vaccination and SARS-CoV2 infection

Darawan Rinchai , Sara Deola , Gabriele Zoppoli , Basirudeen Syed Ahamed Kabeer , Sara Taleb et al.
Science Advances , 2022, 8 (45), eabp9961. ⟨10.1126/sciadv.abp9961⟩
Article dans une revue hal-03530948 v1

Methodological guidelines to estimate population-based health indicators using linked data and/or machine learning techniques

Romana Haneef , Mariken Tijhuis , Rodolphe Thiébaut , Ondřej Májek , Ivan Pristaš et al.
Archives of Public Health, 2022, 80 (9), pp.9. ⟨10.1186/s13690-021-00770-6⟩
Article dans une revue hal-03692820 v1

T Cell Immunogenicity, Gene Expression Profile, and Safety of Four Heterologous Prime-Boost Combinations of HIV Vaccine Candidates in Healthy Volunteers: Results of the Randomized Multi-Arm Phase I/II ANRS VRI01 Trial

Laura Richert , Jean-Daniel Lelievre , Christine Lacabaratz , Lucile Hardel , Hakim Hocini et al.
Journal of Immunology, 2022, 208 (12), pp.2663-2674. ⟨10.4049/jimmunol.2101076⟩
Article dans une revue hal-03690137 v1
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Targeting SARS-CoV-2 receptor-binding domain to cells expressing CD40 improves protection to infection in convalescent macaques

Romain Marlin , Veronique Godot , Sylvain Cardinaud , Mathilde Galhaut , Severin Coleon et al.
Nature Communications, 2021, 12, pp.5215. ⟨10.1038/s41467-021-25382-0⟩
Article dans une revue hal-03481526 v1
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Between group comparison of AUC in clinical trials with censored follow-up: Application to HIV therapeutic vaccines

Marie Alexandre , Mélanie Prague , Rodolphe Thiébaut
Statistical Methods in Medical Research, 2021, ⟨10.1177/09622802211023963⟩
Article dans une revue hal-03241637 v2

Influence of the Antiretroviral Regimen on the Early Changes in Plasma HIV RNA and Immune Activation at Initiation of Antiretroviral Therapy in Naïve HIV-1–Infected Patients

Assia Samri , Mathieu Chalouni , Julià Blanco , Georg Behrens , Peter Kelleher et al.
Journal of Acquired Immune Deficiency Syndromes - JAIDS, 2021, 86 (5), pp.e146-e149. ⟨10.1097/QAI.0000000000002594⟩
Article dans une revue hal-03526543 v1
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EpidemiOptim: a Toolbox for the Optimization of Control Policies in Epidemiological Models

Cédric Colas , Boris P. Hejblum , Sébastien Rouillon , Rodolphe Thiébaut , Pierre-Yves Oudeyer et al.
Journal of Artificial Intelligence Research, 2021, 71, pp.479-515. ⟨10.1613/jair.1.12588⟩
Article dans une revue hal-03099898 v2

Correction to: Evolution of body composition following successful kidney transplantation is strongly influenced by physical activity: results of the CORPOS study

Karine Moreau , Aurélie Desseix , Christine Germain , Pierre Merville , Lionel Couzi et al.
BMC Nephrology, 2021, 22 (1), ⟨10.1186/s12882-021-02258-5⟩
Article dans une revue hal-03186351 v1
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Barrier Gesture Relaxation during Vaccination Campaign in France: Modelling Impact of Waning Immunity

Carole Vignals , David W Dick , Rodolphe Thiébaut , Linda Wittkop , Mélanie Prague et al.
COVID, 2021, 1 (2), pp.472-488. ⟨10.3390/covid1020041⟩
Article dans une revue hal-03375281 v1

Partnership for Research on Ebola VACcination (PREVAC): protocol of a randomized, double-blind, placebo-controlled phase 2 clinical trial evaluating three vaccine strategies against Ebola in healthy volunteers in four West African countries

Moses Badio , Edouard Lhomme , Mark Kieh , Abdoul Habib Beavogui , Stephen Kennedy et al.
Trials, 2021, 22 (1), pp.86. ⟨10.1186/s13063-021-05035-9⟩
Article dans une revue hal-03526667 v1
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A Conceptual Discussion about R0 of SARS-COV-2 in Healthcare Settings

Laura Temime , Marie-Paule Gustin , Audrey Duval , Niccolò Buetti , Pascal Crepey et al.
Clinical Infectious Diseases, 2021, pp.ciaa682. ⟨10.1093/cid/ciaa682⟩
Article dans une revue hal-02859847 v1
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A randomized placebo-controlled efficacy study of a prime boost therapeutic vaccination strategy in HIV-1 infected individuals: VRI02 ANRS 149 LIGHT Phase II trial

Y. Levy , C. Lacabaratz , Edouard Lhomme , A. Wiedemann , Claire Bauduin et al.
Journal of Virology, In press, ⟨10.1128/jvi.02165-20⟩
Article dans une revue hal-03188939 v1
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CD177, a specific marker of neutrophil activation, is associated with coronavirus disease 2019 severity and death

Yves Lévy , Aurélie Wiedemann , Boris P. Hejblum , Mélany Durand , Cécile Lefebvre et al.
iScience, 2021, 24 (7), pp.102711. ⟨10.1016/j.isci.2021.102711⟩
Article dans une revue hal-03477973 v1
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New Insights in Microbial Species Predicting Lung Function Decline in CF: Lessons from the MucoFong Project

Florence Francis , Raphael Enaud , Perrine Soret , Florian Lussac-Sorton , Marta Avalos et al.
Journal of Clinical Medicine, 2021, 10 (16), pp.3725. ⟨10.3390/jcm10163725⟩
Article dans une revue hal-03328143 v1
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mTOR Inhibitors Prevent CMV Infection through the Restoration of Functional αβ and γδ T cells in Kidney Transplantation

Hannah Kaminski , Gabriel Marseres , Nathalie Yared , Marie-Julie Nokin , Vincent Pitard et al.
Journal of the American Society of Nephrology, In press, pp.121-137. ⟨10.1681/ASN.2020121753⟩
Article dans une revue hal-03451674 v1
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Evolution of body composition following successful kidney transplantation is strongly influenced by physical activity: results of the CORPOS study

Karine Moreau , Aurélie Desseix , Christine Germain , Pierre Merville , Lionel Couzi et al.
BMC Nephrology, 2021, 22 (1), pp.31. ⟨10.1186/s12882-020-02214-9⟩
Article dans une revue hal-03142794 v1
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Safety and immunogenicity of 2-dose heterologous Ad26.ZEBOV, MVA-BN-Filo Ebola vaccination in healthy and HIV-infected adults: A randomised, placebo-controlled Phase II clinical trial in Africa

Houreratou Barry , Gaudensia Mutua , Hannah Kibuuka , Zacchaeus Anywaine , Sodiomon Sirima et al.
PLoS Medicine, 2021, 18 (10), pp.e1003813. ⟨10.1371/journal.pmed.1003813⟩
Article dans une revue hal-03481531 v1

Random forests for high-dimensional longitudinal data

Louis Capitaine , Robin Genuer , Rodolphe Thiébaut
Statistical Methods in Medical Research, 2021, 30 (1), pp.166-184. ⟨10.1177/0962280220946080⟩
Article dans une revue hal-03481508 v1
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Health Care Students’ Knowledge of and Attitudes, Beliefs, and Practices Toward the French COVID-19 App: Cross-sectional Questionnaire Study

Ilaria Montagni , Nicolas Roussel , Rodolphe Thiébaut , Christophe Tzourio
Journal of Medical Internet Research, 2021, 23 (3), pp.e26399. ⟨10.2196/26399⟩
Article dans une revue hal-03189015 v1
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Durable natural killer cell responses after heterologous two-dose Ebola vaccination

Helen R. Wagstaffe , Giada Susannini , Rodolphe Thiébaut , Laura Richert , Yves Lévy et al.
NPJ vaccines, 2021, 6 (1), pp.19. ⟨10.1038/s41541-021-00280-0⟩
Article dans une revue hal-03158135 v1
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A machine learning approach for predicting suicidal thoughts and behaviours among college students

Melissa Macalli , Marie Navarro , Massimiliano Orri , Marie Tournier , Rodolphe Thiebaut et al.
Scientific Reports, 2021, 11 (1), pp.11363. ⟨10.1038/s41598-021-90728-z⟩
Article dans une revue hal-03323054 v1
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ESO Guideline on covert cerebral small vessel disease

Joanna M. Wardlaw , Stephanie Debette , Hanna Jokinen , Frank-Erik de Leeuw , Leonardo Pantoni et al.
European Stroke Journal, 2021, ⟨10.1177/23969873211012132⟩
Article dans une revue hal-03282826 v1

The impact of clopidogrel on plasma-soluble CD40 ligand levels in systemic lupus erythematosus patients: the CLOPUS phase I/II pilot study

Guillaume Vial , Noémie Gensous , Hélène Savel , Christophe Richez , Estibaliz Lazaro et al.
Joint Bone Spine, 2021, 88 (2), pp.105097. ⟨10.1016/j.jbspin.2020.105097⟩
Article dans une revue hal-03142764 v1
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Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data

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Interstices, 2020
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Joint Bone Spine, 2020, 88 (2), pp.105097. ⟨10.1016/j.jbspin.2020.105097⟩
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PLoS ONE, 2020, 15 (4), pp.e0230772. ⟨10.1371/journal.pone.0230772⟩
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Nature Communications, 2020, 11 (1), pp.3730. ⟨10.1038/s41467-020-17489-7⟩
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Journal of Theoretical Biology, 2020, 495, pp.110254. ⟨10.1016/j.jtbi.2020.110254⟩
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Correlation between blood telomere length and CD4+ CD8+ T-cell subsets changes 96 weeks after initiation of antiretroviral therapy in HIV-1-positive individuals

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PLoS ONE, 2020, 15 (4), 9 p
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Conventional Dendritic Cells and Slan + Monocytes During HIV-2 Infection

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Frontiers in Immunology, 2020, 1, pp.1658. ⟨10.3389/fimmu.2020.01658⟩
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Respiratory mycobiome and suggestion of inter-kingdom network during acute pulmonary exacerbation in cystic fibrosis

Perrine Soret , Louise-Eva Vandenborght , Florence Francis , Noémie Coron , Raphaël Enaud et al.
Scientific Reports, 2020, 10 (1), pp.3589. ⟨10.1038/s41598-020-60015-4⟩
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Home Treatment of Older People with Symptomatic SARS-CoV-2 Infection (COVID-19): A structured Summary of a Study Protocol for a Multi-Arm Multi-Stage (MAMS) Randomized Trial to Evaluate the Efficacy and Tolerability of Several Experimental Treatments to Reduce the Risk of Hospitalisation or Death in outpatients aged 65 years or older (COVERAGE trial)

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Trials, 2020, 21 (1), ⟨10.1186/s13063-020-04619-1⟩
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Immune Alterations in a Patient with SARS-CoV-2-Related Acute Respiratory Distress Syndrome

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Sodiomon B Sirima , Laura Richert , Arnaud Chêne , Amadou T Konate , Cécilia Campion et al.
The Lancet Infectious Diseases, 2020, 20 (5), pp.585-597. ⟨10.1016/S1473-3099(19)30739-X⟩
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Analyzing cellular immunogenicity in vaccine clinical trials: a new statistical method including non-specific responses for accurate estimation of vaccine effect

Édouard Lhomme , Boris Hejblum , Christine Lacabaratz , Aurélie Wiedemann , Jean-Daniel Lelièvre et al.
Journal of Immunological Methods, 2020, 477, pp.112711. ⟨10.1016/j.jim.2019.112711⟩
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dearseq: a variance component score test for RNA-Seq differential analysis that effectively controls the false discovery rate

Marine Gauthier , Denis Agniel , Rodolphe Thiébaut , Boris Hejblum
NAR Genomics and Bioinformatics, 2020, 2 (4), pp.lqaa093. ⟨10.1093/nargab/lqaa093⟩
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Prospective Evaluation of the First Option, Second-Line Therapy in Childhood Chronic Immune Thrombocytopenia: Splenectomy or Immunomodulation

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Sébastien Cossin , Rodolphe Thiébaut
IMIA Yearbook of Medical Informatics, 2020, 29 (1), pp.231-234. ⟨10.1055/s-0040-1702020⟩
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Exogenous acquisition of Pseudomonas aeruginosa in intensive care units: a prospective multi-centre study (DYNAPYO study)

Maider Coppry , Camille Leroyer , Marion Saly , Anne Gaëlle Venier , Celine Slekovec et al.
Journal of Hospital Infection, 2020, 104 (1), pp.40-45. ⟨10.1016/j.jhin.2019.08.008⟩
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Effects of a physical activity programme to prevent physical performance decline in onco-geriatric patients: a randomized multicentre trial

Haritz Arrieta , Cyril Astrugue , Sophie C Regueme , Jessica Durrieu , Aline Maillard et al.
Journal of Cachexia, Sarcopenia and Muscle, 2019, 10 (2), pp.287-297. ⟨10.1002/jcsm.12382⟩
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New insights are game-changers in HIV-2 disease management

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The Lancet HIV, 2019, 6 (4), pp.e214. ⟨10.1016/s2352-3018(19)30088-8⟩
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Artificial Intelligence for Surveillance in Public Health

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IMIA Yearbook of Medical Informatics, 2019, 28 (1), pp.232-234. ⟨10.1055/s-0039-1677939⟩
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Sequential Dirichlet Process Mixtures of Multivariate Skew t-distributions for Model-based Clustering of Flow Cytometry Data

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Annals of Applied Statistics, 2019, 13 (1), pp.638-660. ⟨10.1214/18-AOAS1209⟩
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Viral rebound in semen after antiretroviral treatment interruption in an HIV therapeutic vaccine double-blind trial

Romain Palich , Jade Ghosn , Antoine Chaillon , Valerie Boilet , Marie-Laure Nere et al.
AIDS. Official journal of the international AIDS Society, 2019, 33 (2), pp.279-284. ⟨10.1097/qad.0000000000002058⟩
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Temporal trends of population viral suppression in the context of Universal Test and Treat: the ANRS 12249 TasP trial in rural South Africa

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Journal of the International AIDS Society, 2019, 22 (10), ⟨10.1002/jia2.25402⟩
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Multi-arm, multi-stage randomised controlled trials for evaluating therapeutic HIV cure interventions

Cecilia Moore , Wolfgang Stohr , Laura Richert , Jean-Daniel Lelievre , Angela Crook et al.
The Lancet HIV, 2019, 6 (5), pp.e334-e340. ⟨10.1016/s2352-3018(19)30082-7⟩
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Innate gene signature distinguishes humoral versus cytotoxic responses to influenza vaccination

Elena Gonçalves , Olivia Bonduelle , Angèle Soria , Pierre Loulergue , Alexandra Rousseau et al.
The Journal of clinical investigation, 2019, 129 (5), pp.1960-1971. ⟨10.1172/jci125372⟩
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Microbial Translocation Does Not Drive Immune Activation in Ugandan Children Infected With HIV

Felicity Fitzgerald , Edouard Lhomme , Kathryn Harris , Julia Kenny , Ronan Doyle et al.
Journal of Infectious Diseases, 2019, 219 (1), pp.89-100. ⟨10.1093/infdis/jiy495⟩
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Dynamics of the humoral immune response to a prime-boost Ebola vaccine: quantification and sources of variation

Chloé Pasin , Irene Balelli , Thierry van Effelterre , Viki Bockstal , Laura Solforosi et al.
Journal of Virology, 2019, 93 (18), pp.e00579-19. ⟨10.1128/jvi.00579-19⟩
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Sequential Dirichlet process mixture of skew $t$-distributions for model-based clustering of flow cytometry data

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Gene Expression Signatures Associated With Immune and Virological Responses to Therapeutic Vaccination With Dendritic Cells in HIV-Infected Individuals

Rodolphe Thiébaut , Boris P. Hejblum , Hakim Hocini , Henri Bonnabau , Jason Skinner et al.
Frontiers in Immunology, 2019, 10, ⟨10.3389/fimmu.2019.00874⟩
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Limited HIV-2 reservoirs in central-memory CD4 T-cells associated to CXCR6 co-receptor expression in attenuated HIV-2 infection

Assia Samri , Charlotte Charpentier , Mariama Sadjo Diallo , Mélanie Bertine , Sophie Even et al.
PLoS Pathogens, 2019, 15 (5), pp.e1007758. ⟨10.1371/journal.ppat.1007758⟩
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Determinants of Restoration of CD4 and CD8 Cell Counts and Their Ratio in HIV-1-Positive Individuals With Sustained Virological Suppression on Antiretroviral Therapy

Luuk Gras , Margaret May , Lars Peter Ryder , Adam Trickey , Marie Helleberg et al.
Journal of Acquired Immune Deficiency Syndromes - JAIDS, 2019, 80 (3), pp.292-300. ⟨10.1097/QAI.0000000000001913⟩
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Innate gene signature distinguishes humoral versus cytotoxic responses to influenza vaccination

Eléna Gonçalves , Olivia Bonduelle , Angèle Soria , Pierre Loulergue , Alexandra Rousseau et al.
Journal of Clinical Investigation, 2019, 129 (5), pp.1960-1971. ⟨10.1172/JCI125372⟩
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HIV Controllers Have Low Inflammation Associated with a Strong HIV-Specific Immune Response in Blood

Hakim Hocini , Henri Bonnabau , Christine Lacabaratz , Cécile Lefebvre , Pascaline Tisserand et al.
Journal of Virology, 2019, 93 (10), pp.e01690-18. ⟨10.1128/JVI.01690-18⟩
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Visualizing omics and clinical data: which challenges for dealing with their variety?

Fleur Mougin , David Auber , Romain Bourqui , Gayo Diallo , Isabelle Dutour et al.
Methods, 2018, 132, pp.3-18. ⟨10.1016/j.ymeth.2017.08.012⟩
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HIV-1 T cell epitopes targeted to Rhesus macaque CD40 and DCIR: A comparative study of prototype dendritic cell targeting therapeutic vaccine candidates

Anne-Laure Flamar , Henri Bonnabau , Sandra Zurawski , Christine Lacabaratz , Monica Montes et al.
PLoS ONE, 2018, 13 (11), pp.e0207794. ⟨10.1371/journal.pone.0207794⟩
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Controlling IL-7 injections in HIV-infected patients

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Lasso regularization for left-censored Gaussian outcome and high-dimensional predictors

Perrine Soret , Marta Fernandez Avalos , Linda Wittkop , Daniel Commenges , Rodolphe Thiébaut
BMC Medical Research Methodology, 2018, 18, pp.13. ⟨10.1186/s12874-018-0609-4⟩
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A Phase Ia/B Study To Assess The Safety And Immunogenicity Of Placental Malaria Vaccine Candidate: Preliminary Results Of The Primalvac Trial

Amadou Konate , Laura Richert , Arnaud Chene , Jean-Philippe Semblat , Gwenaelle Roguet et al.
American Journal of Tropical Medicine and Hygiene, 2018, 99 (4), pp.469-469. ⟨10.1136/bmjgh-2019-EDC.35⟩
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Ebola vaccine development: Systematic review of pre-clinical and clinical studies, and meta-analysis of determinants of antibody response variability after vaccination

Lise Gross , Édouard Lhomme , Chloé Pasin , Laura Richert , Rodolphe Thiébaut
International Journal of Infectious Diseases, 2018, 74, pp.83-96. ⟨10.1016/j.ijid.2018.06.022⟩
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Prevention of Ebola virus disease through vaccination: where we are in 2018

Yves Levy , Clifford Lane , Peter Piot , Abdul Habib Beavogui , Mark Kieh et al.
The Lancet, 2018, 392 (10149), pp.787-790. ⟨10.1016/S0140-6736(18)31710-0⟩
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The impact of population dynamics on the population HIV care cascade: results from the ANRS 12249 Treatment as Prevention trial in rural KwaZulu-Natal (South Africa)

Joseph Larmarange , Hassimiou Mamadou Diallo , Nuala Mcgrath , Collins Iwuji , Melanie Plazy et al.
Journal of the International AIDS Society, 2018, Population mobility: challenges for universal HIV testing and treatment, 21 (Suppl 4), pp.e25128. ⟨10.1002/jia2.25128⟩
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Sparse partial least squares with group and subgroup structure

Matthew Sutton , Rodolphe Thiébaut , Benoit Liquet
Statistics in Medicine, 2018, 37 (23), pp.3338-3356. ⟨10.1002/sim.7821⟩
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Universal test and treat and the HIV epidemic in rural South Africa: a phase 4, open-label, community cluster randomised trial

Collins C. Iwuji , Joanna Orne-Gliemann , Joseph Larmarange , Eric Balestre , Rodolphe Thiébaut et al.
The Lancet HIV, 2018, 5 (3), pp.e116-e125. ⟨10.1016/s2352-3018(17)30205-9⟩
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Risk factors for colonization and infection by Pseudomonas aeruginosa in patients hospitalized in intensive care units in France

S. Hoang , A. Georget , J. Asselineau , Anne-Gaëlle Venier , Camille Leroyer et al.
PLoS ONE, In press, 13 (3), pp.e0193300. ⟨10.1371/journal.pone.0193300⟩
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cytometree: A binary tree algorithm for automatic gating in cytometry analysis

Daniel Commenges , Chariff Alkhassim , Raphael Gottardo , Boris P. Hejblum , Rodolphe Thiébaut
Cytometry Part A, 2018, 93 (11), pp.1132-1140. ⟨10.1002/cyto.a.23601⟩
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A new method for evaluating the impacts of semantic similarity measures on the annotation of gene sets

Aarón Ayllón-Benítez , Fleur Mougin , Julien Allali , Rodolphe Thiébaut , Patricia Thebault
PLoS ONE, 2018, 13 (11), pp.e0208037. ⟨10.1371/journal.pone.0208037⟩
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Prenatal therapy with pyrimethamine + sulfadiazine vs spiramycin to reduce placental transmission of toxoplasmosis: a multicenter, randomized trial

Laurent Mandelbrot , Francois Kieffer , Rémi Sitta , Hélène Laurichesse-Delmas , Norbert Winer et al.
American Journal of Obstetrics and Gynecology, 2018, 219 (4), pp.386.e1-386.e9. ⟨10.1016/j.ajog.2018.05.031⟩
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T-cell and Transcriptomic Responses to Prime-boost Strategies of 3 HIV Vaccines(MVA HIV-B; LIPO-5; GTU-MultiHIV B)-ANRS/INSERM VRI01 Trial

Laura Richert , Aurelie Wiedemann , Odile Launay , Frederic Lucht , Isabelle Poizot-Martin et al.
AIDS Research and Human Retroviruses, 2018, pp.16-16
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Artificial Intelligence in Public Health and Epidemiology

Rodolphe Thiébaut , Frantz Thiessard
IMIA Yearbook of Medical Informatics, 2018, 27 (1), pp.207-210. ⟨10.1055/s-0038-1667082⟩
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Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts

Laura Villain , Daniel Commenges , Chloé Pasin , Mélanie Prague , Rodolphe Thiébaut
Statistics in Medicine, 2018, 38 (2), pp.221-235. ⟨10.1002/sim.7957⟩
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Integrative Analysis of Immunological Data to Explore Chronic Immune T-Cell Activation in Successfully Treated HIV Patients

Marie-Quitterie Picat , Isabelle Pellegrin , Juliette Bitard , Linda Wittkop , Cécile Proust-Lima et al.
PLoS ONE, 2017, 12 (1), pp.e0169164. ⟨10.1371/journal.pone.0169164⟩
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Serum ST2 level is an independent predictor of all-cause mortality in HIV-infected patients. Aquitaine Cohort, France

Rodolphe Thiebaut , Sophie Hue , Fabien Le Marec , Jean-Daniel Lelievre , Michel Dupon et al.
AIDS. Official journal of the international AIDS Society, 2017
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No compensatory lung growth after resection in a one-year follow-up cohort of patients with lung cancer

Stéphane Glénet , Claire De Bisschop , Frédéric Delcambre , Rodolphe Thiébaut , Laurent Francois et al.
Journal of Thoracic Disease, 2017, 9 (10), pp.3938-3945. ⟨10.21037/jtd.2017.08.135⟩
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Public Health and Epidemiology Informatics

Rodolphe Thiebaut , Frantz Thiessard
IMIA Yearbook of Medical Informatics, 2017, ⟨10.15265/IY-2017-035⟩
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Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV

Anne Rechtien , Laura Richert , Hadrien Lorenzo , Gloria Martrus , Boris P. Hejblum et al.
Cell Reports, 2017, 20 (9), pp.2251 - 2261. ⟨10.1016/j.celrep.2017.08.023⟩
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CD4 Cell Count Response to First-Line Combination ART in HIV-2+ Patients Compared with HIV-1+ Patients: A Multinational, Multicohort European Study

Linda Wittkop , Julie Arsandaux , Ana Trevino , Maarten Schim van der Loeff , Jane Anderson et al.
Journal of Antimicrobial Chemotherapy, 2017, 72 (10), pp.2869--2878. ⟨10.1093/jac/dkx210⟩
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Reference curves for CD4 T-cell count response to combination antiretroviral therapy in HIV-1-infected treatment-naïve patients

Vincent Bouteloup , Caroline Sabin , Amanda Mocroft , Luuk Gras , Nikos Pantazis et al.
HIV Medicine, 2017, 18 (1), pp.33 - 44. ⟨10.1111/hiv.12389⟩
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Serum suppression of tumorigenicity 2 level is an independent predictor of all-cause mortality in HIV-infected patients

Rodolphe Thiebaut , Sophie Hue , Fabien Le Marec , Jean-Daniel Lelievre , Michel Dupon et al.
AIDS. Official journal of the international AIDS Society, 2017, 31 (17), pp.2355 - 2365. ⟨10.1097/QAD.0000000000001628⟩
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Modeling CD4 + T cells dynamics in HIV-infected patients receiving repeated cycles of exogenous Interleukin 7

Ana Jarne , Daniel Commenges , Mélanie Prague , Yves Levy , Rodolphe Thiébaut
Annals of Applied Statistics, 2017
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Dynamic models for estimating the effect of HAART on CD4 in observational studies: Application to the Aquitaine Cohort and the Swiss HIV Cohort Study

Mélanie Prague , Daniel Commenges , Jon Michael Gran , Bruno Ledergerber , Jim Young et al.
Biometrics, 2017, 73 (1), pp.294 - 304. ⟨10.1111/biom.12564⟩
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Low CD4/CD8 Ratio Is Associated with Non AIDS-Defining Cancers in Patients on Antiretroviral Therapy: ANRS CO8 (Aproco/Copilote) Prospective Cohort Study

Mariam Noelie Hema , Tristan Ferry , Michel Dupon , Lise Cuzin , Renaud Verdon et al.
PLoS ONE, 2016, 11 (8), pp.e0161594. ⟨10.1371/journal.pone.0161594⟩
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Superior Efficacy of a Human Immunodeficiency Virus Vaccine Combined with Antiretroviral Prevention in Simian-Human Immunodeficiency Virus-Challenged Nonhuman Primates

Roger Le Grand , Nathalie Dereuddre-Bosquet , Stefania Dispinseri , Leslie Gosse , Delphine Desjardins et al.
Journal of Virology, 2016, 90 (11), pp.5315 - 5328
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Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques

Gerard Zurawski , Sandra Zurawski , Anne-Laure Flamar , Laura Richert , Ralf Wagner et al.
PLoS ONE, 2016, 11 (4), ⟨10.1371/journal.pone.0153484⟩
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Immunologic response in treatment-naïve HIV-2-infected patients: the IeDEA West Africa cohort

Eric Balestre , Didier Koumavi Ekouevi , Boris Tchounga , Serge Paul Eholie , Eugène Messou et al.
Journal of the International AIDS Society, 2016, 19 (1), pp.20044. ⟨10.7448/IAS.19.1.20044⟩
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Repeated Cycles of Recombinant Human Interleukin 7 in HIV-Infected Patients With Low CD4 T-Cell Reconstitution on Antiretroviral Therapy: Results of 2 Phase II Multicenter Studies

Rodolphe Thiébaut , Ana Jarne , Jean-Pierre Routy , Irini Sereti , Margaret Fischl et al.
Clinical Infectious Diseases, 2016, 62 (9), pp.1178 - 1185. ⟨10.1093/cid/ciw065⟩
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No Positive Association between Vitamin D Level and Immune Responses to Hepatitis B and Streptococcus pneumoniae Vaccination in HIV-Infected Adults

Jean-Paul Viard , Alex Assuied , Yves Lévy , Jean-Claude Souberbielle , Rodolphe Thiébaut et al.
PLoS ONE, 2016, 11 (12), pp.e0168640. ⟨10.1371/journal.pone.0168640⟩
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Early CD4+ T Cell Responses Are Associated with Subsequent CD8+ T Cell Responses to an rAd5-Based Prophylactic Prime-Boost HIV Vaccine Strategy

Edouard Lhomme , Laura Richert , Zoe Moodie , Chloé Pasin , Spyros A. Kalams et al.
PLoS ONE, 2016, 11 (4)
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Superior efficacy of an HIV vaccine combined with ARV prevention in SHIV challenged non-human primates

Roger Le Grand , Nathalie Bosquet , Stefania Dispinseri , Leslie Gosse , Delphine Desjardins et al.
Journal of Virology, 2016, ⟨10.1128/JVI.00230-16⟩
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A method to estimate the size and characteristics of HIV-positive populations using an individual-based stochastic simulation model

Fumiyo Nakagawa , Ard van Sighem , Rodolphe Thiébaut , Colette Smith , Oliver Ratmann et al.
Epidemiology, 2016, 27 (2), pp.247-256. ⟨10.1097/EDE.0000000000000423⟩
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Intrinsic Defect in Keratinocyte Function Leads to Inflammation in Hidradenitis Suppurativa

Claire Hotz , Michele Boniotto , Aurélie Guguin , Mathieu Surénaud , Francette Jean-Louis et al.
Journal of Investigative Dermatology, 2016, 136 (9), pp.1768 - 1780
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Uptake of Home-Based HIV Testing, Linkage to Care, and Community Attitudes about ART in Rural KwaZulu-Natal, South Africa: Descriptive Results from the First Phase of the ANRS 12249 TasP Cluster-Randomised Trial

Collins C. Iwuji , Joanna Orne-Gliemann , Joseph Larmarange , Nonhlanhla Okesola , Frank Tanser et al.
PLoS Medicine, 2016, 13 (8), ⟨10.1371/journal.pmed.1002107⟩
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Group and sparse group partial least square approaches applied in genomics context

Benoit Liquet , Pierre Lafaye de Micheaux , Boris P. Hejblum , Rodolphe Thiébaut
Bioinformatics, 2016, 32 (1), pp.35-42. ⟨10.1093/bioinformatics/btv535⟩
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Preservation of Lymphopoietic Potential and Virus Suppressive Capacity by CD8+ T Cells in HIV-2-Infected Controllers.

Mathieu Angin , Glenn Wong , Laura Papagno , Pierre Versmisse , Annie David et al.
Journal of Immunology, 2016, 197 (7), pp.2787-95. ⟨10.4049/jimmunol.1600693⟩
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Dose finding with longitudinal data: simpler models, richer outcomes

Xavier Paoletti , Adélaïde Doussau , Monia Ezzalfani , Elisa Rizzo , Rodolphe Thiébaut
Statistics in Medicine, 2015, 34 (22), ⟨10.1002/sim.6552⟩
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Recent developments in clinical trial designs for HIV vaccine research.

Laura Richert , Edouard Lhomme , Catherine Fagard , Yves Levy , Geneviève Chêne et al.
Human Vaccines & Immunotherapeutics, 2015, 11 (4), pp.1022--9. ⟨10.1080/21645515.2015.1011974⟩
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Optimization and evaluation of Luminex performance with supernatants of antigen-stimulated peripheral blood mononuclear cells

Mathieu Surénaud , Céline Manier , Laura Richert , Rodolphe Thiébaut , Yves Levy et al.
BMC Immunology, 2015, 17 (1), pp.44. ⟨10.1186/s12865-016-0182-8⟩
Article dans une revue inserm-01395760 v1

A new approach to integrate toxicity grade and repeated treatment cycles in the analysis and reporting of phase I dose-finding trials

Adélaide Doussau , Rodolphe Thiebaut , B. Geoerger , Patrick Schoffski , Anne Floquet et al.
Annals of Oncology, 2015, 26 (2), pp.422-428. ⟨10.1093/annonc/mdu523⟩
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Guidelines for reporting methodological challenges and evaluating potential bias in dementia research

Jennifer Weuve , Cécile Proust-Lima , Melinda C. Power , Alden L. Gross , Scott M. Hofer et al.
Alzheimer's & Dementia : the Journal of the Alzheimer's Association, 2015, 11 (9), pp.1098-1109. ⟨10.1016/j.jalz.2015.06.1885⟩
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Proposal for a European Public Health Research Infrastructure for Sharing of health and Medical administrative data (PHRIMA).

Anita Burgun , Dina V Oksen , Wolfgang Kuchinke , Hans-Ulrich Prokosch , Thomas Ganslandt et al.
Studies in Health Technology and Informatics, 2015, 216, pp.1005. ⟨10.3233/978-1-61499-564-7-1005⟩
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CD41 T cell recovery during suppression of HIV replication: an international comparison of the immunological efficacy of antiretroviral therapy in North America, Asia and Africa.

Elvin H Geng , Torsten B Neilands , Rodolphe Thièbaut , Mwebesa Bosco Bwana , Denis Nash et al.
International Journal of Epidemiology, 2015, 44 (1), pp.251-63
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Decreased HIV-Specific T-Regulatory Responses Are Associated with Effective DC-Vaccine Induced Immunity

Vedran Brezar , Nicolas Ruffin , Laura Richert , Mathieu Surénaud , Christine Lacabaratz et al.
PLoS Pathogens, 2015, 11 (3), pp.e1004752. ⟨10.1371/journal.ppat.1004752⟩
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Association of immune-activation and senescence markers with non-AIDS-defining comorbidities in HIV-suppressed patients

Pierre Duffau , Linda Wittkop , Estibaliz Lazaro , Fabien Le Marec , Céline Cognet et al.
AIDS. Official journal of the international AIDS Society, 2015, 29 (16), pp.2099-2108. ⟨10.1097/QAD.0000000000000807⟩
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Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients

Ayrin Kök , Laurent Hocqueloux , Hakim Hocini , Marie Carrière , Laurent Lefrou et al.
Mucosal Immunology, 2015, 8 (1), pp.127-140. ⟨10.1038/mi.2014.50⟩
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Parameters identification for a model of T cell homeostasis

Houssein Ayoub , Bedreddine Ainseba , Michel Langlais , Rodolphe Thiébaut
Mathematical Biosciences and Engineering, 2015, 12 (5), pp.917--936. ⟨10.3934/mbe.2015.12.917⟩
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Diabetes and cognitive decline in a French cohort of patients infected with HIV-1

Carole Dufouil , Laura Richert , Rodolphe Thiébaut , Mathias Bruyand , Hélène Amieva et al.
Neurology, 2015, 85 (12), pp.1065-1073. ⟨10.1212/WNL.0000000000001815⟩
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Surveillance of γδ T Cells Predicts Cytomegalovirus Infection Resolution in Kidney Transplants.

Hannah Kaminski , Isabelle Garrigue , Lionel Couzi , Benjamin Taton , Thomas Bachelet et al.
Journal of the American Society of Nephrology, 2015, 27 (2), pp.637-645. ⟨10.1681/ASN.2014100985⟩
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Time-Course Gene Set Analysis for Longitudinal Gene Expression Data

Boris P. Hejblum , Jason Skinner , Rodolphe Thiébaut
PLoS Computational Biology, 2015, 11 (6), pp.e1004310. ⟨10.1371/journal.pcbi.1004310⟩
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Accelerating clinical development of HIV vaccine strategies: methodological challenges and considerations in constructing an optimised multi-arm phase I/II trial design.

Laura Richert , Adélaïde Doussau , Jean-Daniel Lelièvre , Vincent Arnold , Véronique Rieux et al.
Trials, 2014, 15 (1), pp.68. ⟨10.1186/1745-6215-15-68⟩
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T-cell activation discriminates subclasses of symptomatic primary humoral immunodeficiency diseases in adults.

Marie-Quitterie Picat , Rodolphe Thiébaut , François Lifermann , Xavier Delbrel , Daniel Adoue et al.
BMC Immunology, 2014, 15 (1), pp.13. ⟨10.1186/1471-2172-15-13⟩
Article dans une revue inserm-00981320 v1

[Mathematical dynamical models for personalized medicine].

Rodolphe Thiébaut , Mélanie Prague , Daniel Commenges
Médecine/Sciences, 2014, 30 Spec No 2, pp.23-6
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Temporal trends in prognostic markers of HIV-1 virulence and transmissibility: an observational cohort study

Nikos Pantazis , Kholoud Porter , Dominique Costagliola , Andrea de Luca , Jade Ghosn et al.
Lancet HIV, 2014, 1 (3), pp.e119 - e126. ⟨10.1016/S2352-3018(14)00002-2⟩
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Body composition in 98 patients awaiting kidney transplantation.

Karine Moreau , Aurélie Desseix , Christine Germain , Nicole Barthe , Thomas Bachelet et al.
Nutrition, 2014, 30 (2), pp.186-91
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The Impact of the 2013 WHO Antiretroviral Therapy Guidelines on the Feasibility of HIV Population Prevention Trials

Eric Ross , Frank Tanser , Pamela Pei , Marie-Louise Newell , Elena Losina et al.
HIV Clinical Trials, 2014, 15 (5), pp.185-98. ⟨10.1310/hct1505-185⟩
Article dans une revue hal-01108183 v1

L’analyse des « Big Data » en recherche clinique

Rodolphe Thiébaut , Boris P. Hejblum , Laura Richert
Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2014, 62 (1), pp.1-4. ⟨10.1016/j.respe.2013.12.021⟩
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Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination.

David Furman , Boris P. Hejblum , Noah Simon , Vladimir Jojic , Cornelia L. Dekker et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (2), pp.869-74. ⟨10.1073/pnas.1321060111⟩
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Reproducibility issues in science, is P value really the only answer?

Jean Gaudart , Laetitia L. Huiart , P. J. Milligan , Rodolphe Thiebaut , Roch Giorgi
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (19), pp.e1934. ⟨10.1073/pnas.1323051111⟩
Article dans une revue hal-01307492 v1

Quantifying and Predicting the Effect of Exogenous Interleukin-7 on CD4+T Cells in HIV-1 Infection

Rodolphe Thiébaut , Julia Drylewicz , Mélanie Prague , Christine Lacabaratz , Stéphanie Beq et al.
PLoS Computational Biology, 2014, 10 (5), pp.e1003630. ⟨10.1371/journal.pcbi.1003630⟩
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An Evaluation of HIV Elite Controller Definitions within a Large Seroconverter Cohort Collaboration

Ashley D. Olson , Laurence Meyer , Maria Prins , Rodolphe Thiébaut , Deepti Gurdasani et al.
PLoS ONE, 2014, 9 (1), pp.e86719. ⟨10.1371/journal.pone.0086719⟩
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Dendritic cell-based therapeutic vaccine elicits polyfunctional HIV-specific T-cell immunity associated with control of viral load.

Yves Lévy , Rodolphe Thiébaut , Matthieu Montes , Christine Lacabaratz , Louis Sloan et al.
European Journal of Immunology, 2014, 44 (9), pp.2802-10
Article dans une revue hal-01108024 v1

NIMROD: a program for inference via a normal approximation of the posterior in models with random effects based on ordinary differential equations.

Mélanie Prague , Daniel Commenges , Jérémie Guedj , Drylewicz Julia , Rodolphe Thiébaut
Computer Methods and Programs in Biomedicine, 2013, 111 (2), pp.447-458. ⟨10.1016/j.cmpb.2013.04.014⟩
Article dans une revue istex hal-00933752 v1

Cytokine and gene transcription profiles of immune responses elicited by HIV lipopeptide vaccine in HIV-negative volunteers.

Laura Richert , Sophie Hue , Hakim Hocini , Mathieu Raimbault , Christine Lacabaratz et al.
AIDS. Official journal of the international AIDS Society, 2013, 27 (9), pp.1421-31. ⟨10.1097/QAD.0b013e32835f5b60⟩
Article dans une revue hal-00948406 v1

Effect of cytomegalovirus-induced immune response, self antigen-induced immune response, and microbial translocation on chronic immune activation in successfully treated HIV type 1-infected patients: the ANRS CO3 Aquitaine Cohort.

Linda Dr Wittkop , Juliette Bitard , Estibaliz Lazaro , Didier Neau , Fabrice Bonnet et al.
Journal of Infectious Diseases, 2013, 207 (4), pp.622-7. ⟨10.1093/infdis/jis732⟩
Article dans une revue inserm-00936482 v1

Is the current use of 'positivity' thresholds meaningful for evaluating HIV-vaccine immunogenicity endpoints?

Laura Richert , Rodolphe Thiébaut
AIDS. Official journal of the international AIDS Society, 2013, 27 (8), pp.1362-5. ⟨10.1097/QAD.0b013e328360d52e⟩
Article dans une revue inserm-00933696 v1

Dose-finding design using mixed-effect proportional odds model for longitudinal graded toxicity data in phase I oncology clinical trials.

Adélaïde Doussau , Rodolphe Thiébaut , Xavier Paoletti
Statistics in Medicine, 2013, 32 (30), pp.5430-47. ⟨10.1002/sim.5960⟩
Article dans une revue istex hal-00936325 v1

Dynamical models of biomarkers and clinical progression for personalized medicine: the HIV context.

Mélanie Prague , Daniel Commenges , Rodolphe Thiébaut
Advanced Drug Delivery Reviews, 2013, 65 (7), pp.954-65. ⟨10.1016/j.addr.2013.04.004⟩
Article dans une revue istex inserm-00939450 v1

NIMROD: a program for inference via a normal approximation of the posterior in models with random effects based on ordinary differential equations.

Mélanie Prague , Daniel Commenges , Jérémie Guedj , Julia Drylewicz , Rodolphe Thiébaut
Computer Methods and Programs in Biomedicine, 2013, 111 (2), pp.447-58. ⟨10.1016/j.cmpb.2013.04.014⟩
Article dans une revue istex inserm-00939447 v1

Effect of cytomegalovirus-induced immune response, self antigen-induced immune response, and microbial translocation on chronic immune activation in successfully treated HIV type 1-infected patients: the ANRS CO3 Aquitaine Cohort.

Linda Wittkop , Juliette Bitard , Estibaliz Lazaro , Didier Neau , Fabrice Bonnet et al.
The Internet Journal of Infectious Diseases, 2013, 207, pp.622-7
Article dans une revue hal-01101196 v1

Clonally diverse T cell homeostasis is maintained by a common program of cell-cycle control.

Thea Hogan , Andrey Shuvaev , Daniel Commenges , Andrew Yates , Robin Callard et al.
Journal of Immunology, 2013, 190 (8), pp.3985-93. ⟨10.4049/jimmunol.1203213⟩
Article dans une revue inserm-00939457 v1
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A novel approach for biomarker selection and the integration of repeated measures experiments from two assays.

Benoit Liquet , Kim-Anh Lê Cao , Hakim Hocini , Rodolphe Thiébaut
BMC Bioinformatics, 2012, 13 (1), pp.325. ⟨10.1186/1471-2105-13-325⟩
Article dans une revue inserm-00814235 v1
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Mean CD4 cell count changes in patients failing a first-line antiretroviral therapy in resource-limited settings.

Alexandra Calmy , Eric Balestre , Fabrice Bonnet , Andrew Boulle , Eduardo Sprinz et al.
BMC Infectious Diseases, 2012, 12 (1), pp.147. ⟨10.1186/1471-2334-12-147⟩
Article dans une revue inserm-00788673 v1
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Treatment Monitoring of HIV Infected Patients based on Mechanistic Models

Mélanie Prague , Daniel Commenges , Julia Drylewicz , Rodolphe Thiébaut
Biometrics, 2012, 14, pp.171 - 911. ⟨10.1191/0962280205sm390oa⟩
Article dans une revue hal-01579531 v1
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A new method for integrated analysis applied to gene expression and cytokines secretion in response to LIPO-5 vaccine in HIV-negative volunteers

Rodolphe Thiébaut , Benoit Liquet , Hakim Hocini , Sophie Hue , Laura Richert et al.
Retrovirology, 2012, 9 (Suppl 2), pp.P121
Article dans une revue inserm-00731770 v1

Heterogeneity in outcomes of treated HIV-positive patients in Europe and North America: relation with patient and cohort characteristics.

Margaret T May , Robert S Hogg , Amy C Justice , Bryan E Shepherd , Dominique Costagliola et al.
International Journal of Epidemiology, 2012, 41 (6), pp.1807-20. ⟨10.1093/ije/dys164⟩
Article dans une revue hal-00875138 v1
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Vaccination with dendritic cells loaded with HIV-1 lipopeptides elicits broad T cell immunity and control of viral load in HIV infected patients

Yves Lévy , Rodolphe Thiébaut , Monica Montes , Christine Lacabaratz , Louis Sloan et al.
Retrovirology, 2012, 9 (Suppl 2), pp.P328
Article dans une revue inserm-00731768 v1

CMV plasma DNAemia and risk of cancer among HIV-infected patients: a case-control study nested in the ANRS CO3 Aquitaine Cohort, France, 2002-2007.

Mathias Bruyand , Marie-Anne Vandenhende , Guillaume Marcel , Estibaliz Lazaro , Marie-Edith Lafon et al.
J Clin Virol, 2011, 50 (2), pp.177-80. ⟨10.1016/j.jcv.2010.10.021⟩
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Universal definition of loss to follow-up in HIV treatment programs: a statistical analysis of 111 facilities in Africa, Asia, and Latin America.

Benjamin H. Chi , Constantin T. Yiannoutsos , Andrew O. Westfall , Jamie E. Newman , Jialun Zhou et al.
PLoS Medicine, 2011, 8 (10), pp.e1001111. ⟨10.1371/journal.pmed.1001111⟩
Article dans une revue inserm-00702729 v1
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Quantification of the relative importance of CTL, B cell, NK cell, and target cell limitation in the control of primary SIV-infection.

Marjet Elemans , Rodolphe Thiébaut , Amitinder Kaur , Becca Asquith
PLoS Computational Biology, 2011, 7 (3), pp.e1001103. ⟨10.1371/journal.pcbi.1001103⟩
Article dans une revue inserm-00704808 v1
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Comparison of early CD4 T-cell count in HIV-1 seroconverters in Côte d'Ivoire and France: the ANRS PRIMO-CI and SEROCO cohorts.

Charlotte Lewden , Rodolphe Thiébaut , Faroudy Boufassa , Ali Coulibaly , Karen Malateste et al.
Journal of Acquired Immune Deficiency Syndromes - JAIDS, 2010, 53 (2), pp.260-5. ⟨10.1097/QAI.0b013e3181b84260⟩
Article dans une revue inserm-00416572 v1
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Prevalence and factors associated with renal impairment in HIV-infected patients, ANRS C03 Aquitaine Cohort, France.

E. Kossi Déti , Rodolphe Thiébaut , Fabrice Bonnet , Sylvie Lawson-Ayayi , Michel Dupon et al.
HIV Medicine, 2010, 11 (5), pp.308-17. ⟨10.1111/j.1468-1293.2009.00780.x⟩
Article dans une revue inserm-00411631 v1

Evolution of 2-long terminal repeat (2-LTR) episomal HIV-1 DNA in raltegravir-treated patients and in in vitro infected cells.

Sandrine Reigadas , Marie-Line Andréola , Linda Wittkop , Ophélie Cosnefroy , Guerric Anies et al.
Journal of Antimicrobial Chemotherapy, 2010, 65 (3), pp.434-7. ⟨10.1093/jac/dkp473⟩
Article dans une revue hal-00522698 v1
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First-year lymphocyte T CD4+ response to antiretroviral therapy according to the HIV type in the IeDEA West Africa collaboration.

Julia Drylewicz , Serge Eholie , Moussa Maiga , Djimon-Marcel Zannou , Papa-Salif Sow et al.
AIDS. Official journal of the international AIDS Society, 2010, 24 (7), pp.1043-50
Article dans une revue inserm-00414621 v1
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Influence of mannose-binding lectin genotypes and serostatus in allo-SCT: analysis of 131 recipients and donors.

Olaf-Werner Neth , Ulrike Bacher , Purnima Das , Tatjana Zabelina , Hartmut Kabisch et al.
Bone Marrow Transplantation, 2010, 45 (1), pp.13-9. ⟨10.1038/bmt.2009.90⟩
Article dans une revue inserm-00414612 v1
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A new endpoint definition improved clinical relevance and statistical power in a vaccine trial.

Gaëlle Pédrono , Rodolphe Thiébaut , Ahmadou Alioum , Philippe Lesprit , Bernard Fritzell et al.
Journal of Clinical Epidemiology, 2009, 62 (10), pp.1054-61. ⟨10.1016/j.jclinepi.2008.10.014⟩
Article dans une revue inserm-00339872 v1
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Virological and immunological response in HIV-1-infected patients with multiple treatment failures receiving raltegravir and optimized background therapy, ANRS CO3 Aquitaine Cohort.

Linda Wittkop , Dominique Breilh , Daniel Da-Silva , Pierre Duffau , Patrick Mercié et al.
Journal of Antimicrobial Chemotherapy, 2009, 63 (6), pp.1251-5. ⟨10.1093/jac/dkp114⟩
Article dans une revue inserm-00372614 v1
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Enhanced T cell recovery in HIV-1-infected adults through IL-7 treatment.

Yves Levy , Christine Lacabaratz , Laurence Weiss , Jean-Paul Viard , Cecile Goujard et al.
Journal of Clinical Investigation, 2009, 119 (4), pp.997-1007. ⟨10.1172/JCI38052⟩
Article dans une revue inserm-00484803 v1
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Non-AIDS-defining deaths and immunodeficiency in the era of combination antiretroviral therapy.

Benoît Marin , Rodolphe Thiébaut , Heiner C. Bucher , Virginie Rondeau , Dominique Costagliola et al.
AIDS. Official journal of the international AIDS Society, 2009, 23 (13), pp.1743-53. ⟨10.1097/QAD.0b013e32832e9b78⟩
Article dans une revue inserm-00388946 v1
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Role of uncontrolled HIV RNA level and immunodeficiency in the occurrence of malignancy in HIV-infected patients during the combination antiretroviral therapy era: Agence Nationale de Recherche sur le Sida (ANRS) CO3 Aquitaine Cohort.

Mathias Bruyand , Rodolphe Thiébaut , Sylvie Lawson-Ayayi , Pierre Joly , Annie-Jeanne Sasco et al.
Clinical Infectious Diseases, 2009, 49 (7), pp.1109-16. ⟨10.1086/605594⟩
Article dans une revue inserm-00391182 v1
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Association of non-HDL cholesterol with subclinical atherosclerosis in HIV-positive patients.

Stéphanie Badiou , Rodolphe Thiébaut , Valérie Aurillac-Lavignolle , Francois Dabis , Frédéric Laporte et al.
Journal of Infection, 2008, 57 (1), pp.47-54. ⟨10.1016/j.jinf.2008.05.007⟩
Article dans une revue inserm-00280760 v1
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Transmission of HIV-1 minority-resistant variants and response to first-line antiretroviral therapy.

Olivia Peuchant , Rodolphe Thiébaut , Sophie Capdepont , Valerie Lavignolle-Aurillac , Didier Neau et al.
AIDS. Official journal of the international AIDS Society, 2008, 22 (12), pp.1417-23. ⟨10.1097/QAD.0b013e3283034953⟩
Article dans une revue inserm-00270200 v1
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Comparison of viro-immunological marker changes between HIV-1 and HIV-2-infected patients in France.

Julia Drylewicz , Sophie Matheron , Estibaliz Lazaro , Florence Damond , Fabrice Bonnet et al.
AIDS. Official journal of the international AIDS Society, 2008, 22 (4), pp.457-68. ⟨10.1097/QAD.0b013e3282f4ddfc⟩
Article dans une revue inserm-00258131 v1
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Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire.

Didier Koumavi Ekouevi , Patrick A. Coffie , Renaud Becquet , Besigin Tonwe-Gold , Apollinaire Horo et al.
AIDS. Official journal of the international AIDS Society, 2008, 22 (14), pp.1815-20. ⟨10.1097/QAD.0b013e32830b8ab9⟩
Article dans une revue inserm-00285869 v1
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When it is better to estimate a slope with only one point.

Thiebaut Rodolphe , Sarah Walker
QJM, 2008, 101 (10), pp.821-4. ⟨10.1093/qjmed/hcn099⟩
Article dans une revue inserm-00336900 v1
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Reduced bone mineral density in HIV-infected patients: prevalence and associated factors.

Charles Cazanave , Michel Dupon , Valérie Lavignolle-Aurillac , Nicole Barthe , Sylvie Lawson-Ayayi et al.
AIDS. Official journal of the international AIDS Society, 2008, 22 (3), pp.395-402. ⟨10.1097/QAD.0b013e3282f423dd⟩
Article dans une revue inserm-00186715 v1
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Alternative methods to analyse the impact of HIV mutations on virological response to antiviral therapy.

Linda Wittkop , Daniel Commenges , Isabelle Pellegrin , Dominique Breilh , Didier Neau et al.
BMC Medical Research Methodology, 2008, 8 (1), pp.68. ⟨10.1186/1471-2288-8-68⟩
Article dans une revue inserm-00333577 v1
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Prevalence of resistance to nevirapine in mothers and children after single-dose exposure to prevent vertical transmission of HIV-1: a meta-analysis.

Elise Arrivé , Marie-Louise Newell , Didier K. Ekouevi , Marie-Laure Chaix , Rodolphe Thiébaut et al.
International Journal of Epidemiology, 2007, 36 (5), pp.1009-21. ⟨10.1093/ije/dym104⟩
Article dans une revue inserm-00187308 v1
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Practical identifiability of HIV dynamics models.

Jérémie Guedj , Rodolphe Thiébaut , Daniel Commenges
Bulletin of Mathematical Biology, 2007, 69 (8), pp.2493-513. ⟨10.1007/s11538-007-9228-7⟩
Article dans une revue inserm-00204273 v1
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Effectiveness of prenatal treatment for congenital toxoplasmosis: a meta-analysis of individual patients' data

Rodolphe Thiébaut , Sandy Leproust , Geneviève Chêne , Ruth Gilbert
The Lancet, 2007, 369 (9556), pp.115-122
Article dans une revue hal-00143965 v1
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Robustness of the linear mixed model to misspecied error distribution

Hélène Jacqmin-Gadda , Solenne Sibillot , Cécile Proust , Jean-Michel Molina , Rodolphe Thiébaut
Computational Statistics and Data Analysis, 2007, 51 (10), pp.5142-5154. ⟨10.1016/j.csda.2006.05.021⟩
Article dans une revue inserm-00084214 v1
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Maximum likelihood estimation in dynamical models of HIV.

Jérémie Guedj , Rodolphe Thiébaut , Daniel Commenges
Biometrics, 2007, 63 (4), pp.1198-206. ⟨10.1111/j.1541-0420.2007.00812.x⟩
Article dans une revue inserm-00204269 v1
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Estimation of dynamical model parameters taking into account undetectable marker values.

Rodolphe Thiébaut , Jérémie Guedj , Hélène Jacqmin-Gadda , Geneviève Chêne , Pascale Trimoulet et al.
BMC Medical Research Methodology, 2006, 6, pp.38. ⟨10.1186/1471-2288-6-38⟩
Article dans une revue inserm-00101223 v1
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Change in T-lymphocyte count after initiation of highly active antiretroviral therapy in HIV-infected patients with history of Mycobacterium avium complex infection.

Estibaliz Lazaro , Gaelle Coureau , Jérémie Guedj , Patrick Blanco , Isabelle Pellegrin et al.
Antiviral Therapy, 2006, 11 (3), pp.343-50
Article dans une revue hal-00143964 v1
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Immunological markers after long-term treatment interruption in chronically HIV-1 infected patients with CD4 cell count above 400 x 10(6) cells/l.

Rodolphe Thiébaut , Isabelle Pellegrin , Geneviève Chêne , Jean François Viallard , Hervé Fleury et al.
AIDS. Official journal of the international AIDS Society, 2005, 19 (1), pp.53-61
Article dans une revue hal-00143966 v1
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Modélisation longitudinale de données incomplètes : exemple de la charge virale plasmatique du VIH

Rodolphe Thiébaut , Hélène Jacqmin-Gadda
Journal de la Société Française de Statistique, 2004, 145 (2), pp.33-47
Article dans une revue inserm-00149860 v1
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Modèles de sélection pour données longitudinales gaussiennes : application à l'étude du vieillissement cognitif

Hélène Jacqmin-Gadda , Rodolphe Thiébaut
Journal de la Société Française de Statistique, 2004, 145 (2), pp.19-32
Article dans une revue inserm-00262012 v1
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[Joint modeling of quantitative longitudinal data and censored survival time]

Hélène Jacqmin-Gadda , Rodolphe Thiébaut , Jean-François Dartigues
Epidemiology and Public Health = Revue d'Epidémiologie et de Santé Publique, 2004, 52 (6), pp.502-10
Article dans une revue inserm-00262018 v1
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Mixed models for longitudinal left-censored repeated measures.

Rodolphe Thiébaut , Hélène Jacqmin-Gadda
Computer Methods and Programs in Biomedicine, 2004, 74 (3), pp.255-60. ⟨10.1016/j.cmpb.2003.08.004⟩
Article dans une revue hal-00143962 v1
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Changes over calendar time in the risk of specific first AIDS-defining events following HIV seroconversion, adjusting for competing risks.

Abdel Babiker , Janet Darbyshire , Patrizio Pezzotti , Kholoud Porter , Giovanni Rezza et al.
International Journal of Epidemiology, 2002, 31 (5), pp.951-8
Article dans une revue inserm-00263560 v1
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Bivariate linear mixed models using SAS proc MIXED.

Rodolphe Thiébaut , Hélène Jacqmin-Gadda , Geneviève Chêne , Catherine Leport , Daniel Commenges
Computer Methods and Programs in Biomedicine, 2002, 69 (3), pp.249-56
Article dans une revue hal-00143963 v1
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Weight loss and body mass index as predictors of HIV disease progression to AIDS in adults. Aquitaine cohort, France, 1985-1997.

Denis Malvy , Rodolphe Thiébaut , Catherine Marimoutou , François Dabis , Groupe d'Épidémiologie Clinique Du Sida En Aquitaine
Journal of the American College of Nutrition, 2001, 20 (6), pp.609-15
Article dans une revue inserm-00263470 v1
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Reservoir Computing for Short High-Dimensional Time Series: an Application to SARS-CoV-2 Hospitalization Forecast

Thomas Ferté , Dan Dutartre , Boris P. Hejblum , Romain Griffier , Vianney Jouhet et al.
ICML'24: Proceedings of the 41st International Conference on Machine Learning, Jul 2024, Vienna, Austria. pp.13570--13591, ⟨10.5555/3692070⟩
Communication dans un congrès hal-04693930 v1
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Optimizing Reservoir Computing with Genetic Algorithm for High-Dimensional SARS-CoV-2 Hospitalization Forecasting: Impacts of Genetic Algorithm Hyperparameters on Feature Selection and Reservoir Computing Hyperparameter Tuning

Thomas Ferté , Dan Dutartre , Boris P. Hejblum , Romain Griffier , Vianney Jouhet et al.
EA 2024 - 16th International Conference Artificial Evolution, Pierrick Legrand, Oct 2024, Bordeaux, France
Communication dans un congrès hal-04905975 v1
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Méthodes pour l'inférence post-clustering appliquées à l'expression génique

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum
SFDS 2022 - Journées de Statistique de la SFdS, Jun 2022, Lyon, France
Communication dans un congrès hal-03906534 v1

Multiblock supervised analyses, should we really normalize blocks?

Jérôme Saracco , Hadrien Lorenzo , Olivier Cloarec , Rodolphe Thiébaut
17th Scandinavian Symposium on Chemometrics (SSC17), Sep 2021, Aalborg, Denmark
Communication dans un congrès hal-03842510 v1
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Inférence post-clustering pour l'identification des variables responsables de la séparation de paires de clusters

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris Hejblum
Journées nationales « Statistiques & Santé » 2021, Oct 2021, Virtuel, France
Communication dans un congrès hal-03906520 v1

Une PLS parcimonieuse entre Statistique et Apprentissage

Jérôme Saracco , Hadrien Lorenzo , Olivier Cloarec , Rodolphe Thiébaut
Journées de Statistique 2021 – Société Française de Statistique, Jun 2021, Nice, France
Communication dans un congrès hal-03842522 v1

Comparison of AUC in clinical trials with follow up censoring: Application to HIV therapeutic vaccines

Marie Alexandre , Mélanie Prague , Yves Lévy , Thiebaut Rodolphe
ISCB 2020 - 41th Annual Conference of the International Society for Clinical Biostatistics, Aug 2020, Krakow / Virtual, Poland
Communication dans un congrès hal-03151377 v1

High-Dimensional Multi-Block Analysis of Factors Associated with Thrombin Generation Potential

Hadrien Lorenzo , Misbah Razzaq , Jacob Odeber , Pierre-Emmanuel Morange , Jérôme Saracco et al.
CBMS 2019 - 32nd IEEE International Symposium on Computer-Based Medical Systems (CBMS), Jun 2019, Cordoba, Spain. pp.453-458, ⟨10.1109/CBMS.2019.00094⟩
Communication dans un congrès hal-02429302 v1
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From individual care trajectories to HIV care cascade at population level in rural KwaZulu-Natal (South Africa): the impact of population dynamics

Joseph Larmarange , Hassimiou Mamadou Diallo , Nuala Mcgrath , Collins Iwuji , Rodolphe Thiébaut et al.
Life History Research Society Conference, May 2018, Paris, France
Communication dans un congrès ird-04088658 v1

Une PLS multivoie parcimonieuse avec observations manquantes pour données hétérogènes

Hadrien Lorenzo , Jérôme Saracco , Rodolphe Thiébaut
Journées de Statistique 2018 - Société Française de Statistique, May 2018, EDF Lab Paris Saclay, France
Communication dans un congrès hal-01963431 v1
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Use of mathematical modeling for optimizing and adapting immunotherapy protocols in HIV-infected patients

Chloé Pasin , Laura Villain , François Dufour , Daniel Commenges , Mélanie Prague et al.
Population Approach Group Europe, May 2018, Montreux, Switzerland
Communication dans un congrès hal-01934340 v1

Multi-block high-dimensional lasso-penalized analysis with imputation of missing data applied to postgenomic data in an Ebola vaccine trial

Hadrien Lorenzo , Rodolphe Thiébaut , Jérôme Saracco
Annual workshop on Statistical Methods for Post Genomic Data - SMPGD 2018, Jan 2018, Montpellier, France
Communication dans un congrès hal-01664610 v1
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Adaptive protocols based on predictions from a mechanistic model of the effect of IL7 on CD4 counts

Laura Villain , Daniel Commenges , Mélanie Prague , Chloé Pasin , Rodolphe Thiébaut
International Biometric Conference, Jul 2018, Bacelone, Spain
Communication dans un congrès hal-01973877 v1
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High-dimensional compositional microbiota data: state-of-the-art of methods and software implementations

Perrine Soret , Marta Fernandez Avalos , Soon Cheng , Rodolphe Thiebaut
2017 - GDR « Statistiques et santé », Oct 2017, Bordeaux, France
Communication dans un congrès hal-01667295 v1
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Joint-state and parameters estimation using nudging and SEIK filters for HIV mechanistic models

Mélanie Prague , Rodolphe Thiébaut , Philippe Moireau , Annabelle Collin
Journée de la statistique francaise, Jun 2017, Avignon, France
Communication dans un congrès hal-01579068 v1

Linking health and administrative data for maternal, child and young adult health

Anita Burgun , Dina V Oksen , Wolfgang Kuchinke , Hans-Ulrich Prokosch , Thomas Ganslandt et al.
9. European Public Health Conference, Nov 2016, Vienne, Austria. ⟨10.1093/eurpub/ckw168.038⟩
Communication dans un congrès hal-01861720 v1
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The impact of universal test and treat on HIV incidence in a rural South African population: ANRS 12249 TasP trial, 2012-2016

Collins Iwuji , Joanna Orne-Gliemann , Eric Balestre , Joseph Larmarange , Rodolphe Thiébaut et al.
21st International AIDS Conference (AIDS 2016), IAS, Jul 2016, Durban, South Africa
Communication dans un congrès hal-04118928 v1

Lasso-type estimators for non-parametric mixed-effects models: application to high-dimensional data from a vaccine clinical trial for HIV

Perrine Soret , Cristian Meza , Marta Fernandez Avalos , Karine Bertin , Rodolphe Thiébaut
3rd conference of the International Society for Non-Parametric Statistics (ISNPS), Jun 2016, Avignon, France
Communication dans un congrès hal-01396378 v1

Lasso pour données censurées à gauche : une comparaison par simulation d’algorithmes proposés dans la littérature

Perrine Soret , Marta Fernandez Avalos , Linda Wittkop , Rodolphe Thiébaut , Daniel Commenges
47èmes Journées de la Statistique, SFdS, 2015, Lille, France
Communication dans un congrès hal-01578293 v1

Feasibility and acceptability of an antiretroviral treatment as prevention (TasP) intervention in rural South Africa: results from the ANRS 12249 TasP cluster-randomised trial

Collins Iwuji , Joanna Orne-Gliemann , Frank Tanser , Rodolphe Thiébaut , Joseph Larmarange et al.
20th International AIDS Conference, IAS, Jul 2014, Melbourne, Australia
Communication dans un congrès hal-04118836 v1

Prise en compte de la censure à gauche dans la modélisation de données de grande dimension

Nastasia Fouret , Marta Avalos , Linda Wittkop , Rodolphe Thiebaut , Daniel Commenges
46e Journées de Statistique, Jun 2014, Rennes, France
Communication dans un congrès hal-01099341 v1
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Test du score pour l'exploration de modèles complexes: Application à la modélisation dynamique du VIH.

Julia Drylewicz , Daniel Commenges , Rodolphe Thiébaut
41èmes Journées de Statistique, SFdS, Bordeaux, 2009, Bordeaux, France, France
Communication dans un congrès inria-00386586 v1

Running in circles: practical limitations for real-life application of data fission and data thinning in post-clustering differential analysis

Benjamin Hivert , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum
2024
Pré-publication, Document de travail hal-04745517 v1

Distribution-free complex hypothesis testing for single-cell RNA-seq differential expression analysis

Marine Gauthier , Denis Agniel , Rodolphe Thiébaut , Boris P. Hejblum
2021
Pré-publication, Document de travail hal-03478097 v1

Gene Set Analysis for time-to-event outcome with the Generalized Berk–Jones statistic

Laura Villain , Thomas Ferté , Rodolphe Thiébaut , Boris P. Hejblum
2021
Pré-publication, Document de travail hal-03478102 v1
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Estimating R0 of SARS-COV-2 in healthcare settings

Laura Temime , Marie-Paule Gustin , Audrey Duval , Niccolo Buetti , Pascal Crepey et al.
2020
Pré-publication, Document de travail hal-02625428 v1
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Population modeling of early COVID-19 epidemic dynamics in French regions and estimation of the lockdown impact on infection rate

Mélanie Prague , Linda Wittkop , Quentin Clairon , Dan Dutartre , Rodolphe Thiébaut et al.
2020
Pré-publication, Document de travail hal-02555100 v1

Random forests for high-dimensional longitudinal data

Louis Capitaine , Robin Genuer , Rodolphe Thiébaut
2019
Pré-publication, Document de travail hal-02002979 v1
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HETEROGENEOUS VIRAL ENVIRONMENT IN A HIV SPATIAL MODEL

Claude-Michel Brauner , Danaelle Jolly , Luca Lorenzi , Rodolphe Thiébaut
2009
Pré-publication, Document de travail hal-00383320 v1
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Modélisation longitudinales de marqueur du VIH

Rodolphe Thiébaut
Sciences du Vivant [q-bio]. Université Victor Segalen - Bordeaux II, 2002. Français. ⟨NNT : ⟩
Thèse tel-00121899 v1