Ronan Kapetanovic
- Infectiologie et Santé Publique (ISP)
Présentation
How to overcome multi-drug resistant bacteria? That is one of my main research topics. Since my PhD at the Pasteur Institute, I have been working on identifying how our immune system recognise bacteria and searching for new ways to improve our antimicrobial response against those pathogens. With the rise of multi-drug resistant bacteria, this question has become of paramount importance. I am interrested in the complexity of the antimicrobial response in macrophages that use mitochondria dynamic, metal ions like zinc or copper, lipid droplets. I am also keen on understanding how pathogens evade this antimicrobial arsenal, in particular Salmonella.
Domaines de recherche
Publications
Publications
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Models of avian intestinal mucosa interaction with commensal and pathogenic bacteria: present and future investigationsPAHW SOA18 2026 Webinar, PAHW SOA18 Coordinator : Nuria Mach-Casellas, Jan 2026, Paris ( France), France. 21 p |
Fighting Salmonella - Time to zinc outside the box!Salmonella on the beach, Laurent Aussel Jay Hinton, CNRS, Jul 2026, Marseille, France |
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[invited] Zincking out of the box: insights into a new antimicrobial response of macrophagesSeminar VIM, Delphyne Descamps, Jun 2026, Jouy en Josas, France |
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Discovering new antimicrobial pathways: mitochondrial dynamics drives immune responses in macrophageLoire Val-Health Scientific Days 2026, Loire Val-Health, Jul 2026, La Ville-aux-Dames, France |
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Heavy Metal and Bacteria: Deciphering how Zinc is deployed as an antimicrobial response20e congrès national de la Société Française de Microbiologie, SFM, Sep 2025, Bordeaux, France |
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[invited] Don’t Zink twice. How macrophages harness metal ions to destroy bacteriaFarewell Symposium for P. Matthias, The Friedrich Miescher Institute for Biomedical Research (FMI), Jun 2025, Basel (CH), Switzerland |
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The Brass Dagger: How macrophages deploy Zinc and Copper as an antibacterial weapon?FrenchBic annual meeting / French-Japanese Symposium on BioInorganic chemistry, FrenchBic, Apr 2024, Marseille, France |
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[invited] “OutZincking” Bacteria - Le rôle des métaux de transition lors de la réponse anti-bactérienne du macrophage.1ère Journée du Club Macrophage & Co - Grand Ouest, Oct 2023, Rennes, France |
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[invited] A chink in the armour. Zinc poisoning and bacterial membrane targeting as a promising two-pronged antimicrobial strategyInternational Conference of Trace Element and Minerals (ICTEM), Jun 2022, Aachen, Germany |
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T8: A particular HDAC: cytoplasmic Histone Deacetylase 6 regulates antimicrobial functions and immunometabolism in macrophages6th Annual Meeting of the Upper-Rhine Immunology (URI) Group, Oct 2022, Karlsruhe, Germany |
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Development of dual single-cell RNA sequencing to characterize molecular mechanisms of the macrophage zinc toxicity antimicrobial response against intracellular E. coli21st Brisbane Immunology Group Annual Retreat, Aug 2022, Gold Coast, Australia. pp.1 |
More than the powerhouse of the cell; Mitchondrial dynamics modulate a new antimicrobial pathway in macrophagesEuropean Society of Macrophages and Dendritic Cells (EMDS), Jun 2021, Virtual conference, Denmark |
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More than the powerhouse of the cell. Mitochondrial dynamics modulate a new antibacterial pathway in macrophagesBasel Postdoc Network Meeting 2021, Oct 2021, Kandersteg, Switzerland |
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Unravelling mechanisms and functions of TLR-inducible mitochondrial fission in macrophages3rd Melbourne Immunometabolism Symposium, Sep 2021, Melbourne, Australia |
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Histone deacetylase 7 coordinates innate immune defence by promoting phagocytosis, NADPH oxidase dependent reactive oxygen species production and bacterial clearanceLorne Infection and Immunity 2021, Feb 2021, Virtual conference, Australia |
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Community annotation of immunity-related genes in the pig genome4. International Symposium on Animal Functional Genomics, Oct 2011, Dublin, Ireland |
Zinc and Destroy! The impact of the serotype of Salmonella on the resistance to metal ion20e congrès national de la Société Française de Microbiologie, Sep 2025, Bordeaux, France |
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Mitochondrial fission-inducible lipid droplets in macrophage antimicrobial responses7th European Congress of Immunology, Sep 2024, Dublin (IR), Ireland. , European Journal of Immunology, 54 (Supplement 1), pp.834, 2024, ECI 2024 |
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Divide and conquer. Mitochondrial fission regulates a new antibacterial pathway in macrophagesAnnual Meeting of the French Society for Immunology 2021, Dec 2021, Paris, France |
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Tracking variability in the antimicrobial zinc toxicity response of human macrophages against Escherichia coli (#267)Lorne Infection and Immunity 2021, Feb 2021, Virtual conference, Australia |
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Unravelling mechanisms of TLR-inducible mitochondrial fission in macrophages (#276)Lorne Infection and Immunity 2021, Feb 2021, Virtual Conference, Australia |
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Structural and functional annotation of immunity-related genes in the pig genome20. Plant and Animal Genome Conference, Jan 2012, San Diego, United States. 2012 |
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Annotation of the immunity-related genes in the pig genome32nd Conference of the International Society of Animal Genetics (ISAG), Jul 2010, Edinburgh, United Kingdom. 2010 |
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Quantifying Regulated Mitochondrial Fission in MacrophagesEffector-Triggered Immunity, 2523, Springer US, pp.281-301, 2022, Methods in Molecular Biology, ⟨10.1007/978-1-0716-2449-4_18⟩ |
Evolutionary Divergence in Human Versus Mouse Innate Immune Gene Regulation and FunctionEvolutionary Biology: Genome Evolution, Speciation, Coevolution and Origin of Life, Springer International Publishing, pp.115-155, 2014, ⟨10.1007/978-3-319-07623-2_6⟩ |