Sami Ben Hamida

Documents

Publications

	Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies Fahd François Hilal , Jerome Jeanblanc , Chloé Deschamps , Mickael Naassila , Olivier Pierrefiche Journal of Neural Transmission, 2024, ⟨10.1007/s00702-024-02757-3⟩ Journal articles hal-04530543v1
	Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies Mickael Fer , Camille Amalric , Roberto Arban , Luc Baron , Sami Ben Hamida Journal of Medicinal Chemistry, 2024, 67 (13), pp.11296-11325. ⟨10.1021/acs.jmedchem.4c00665⟩ Journal articles hal-04633156v1
	Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation Md Toufiqur Rahman , Ann Decker , Sami Ben Hamida , David Perrey , Hetti Handi Chaminda Lakmal Journal of Medicinal Chemistry, 2023, ⟨10.1021/acs.jmedchem.2c01983⟩ Journal articles hal-03980716v1
	Mu opioid receptors-expressing neurons in the dorsal raphe nucleus are involved in reward processing and affective behaviors Lola Welsch , Esther Colantonio , Mathilde Frison , Desiree Johnson , Shannan Mcclain Biological Psychiatry, 2023, ⟨10.1016/j.biopsych.2023.05.019⟩ Journal articles hal-04121491v1
	Mu Opioid Receptor–Positive Neurons in the Dorsal Raphe Nucleus Are Impaired by Morphine Abstinence Lola Welsch , Esther Colantonio , Camille Falconnier , Cédric Champagnol-Diliberti , Florence Allain Biological Psychiatry, 2023, 94 (11), pp.852-862. ⟨10.1016/j.biopsych.2023.06.024⟩ Journal articles hal-04296743v1
	Role of GPR88 in ethanol drinking: A new pharmacological target Sami Ben Hamida , M. Carter , E. Darcq , M. Sourty , Md T. Rahman Alcoholism: Clinical and Experimental Research, 2022, 46 (2, SI), pp.57 Journal articles hal-03783447v1
	The GPR88 agonist RTI-13951-33 reduces alcohol drinking and seeking in mice Sami Ben Hamida , Michelle Carter , Emmanuel Darcq , Marion Sourty , Md Toufiqur Rahman Addiction Biology, 2022, 27 (6), ⟨10.1111/adb.13227⟩ Journal articles hal-03767753v1
	Translational structural and functional signatures of chronic alcohol effects in mice Laëtitia Degiorgis , Tanzil Mahmud Arefin , Sami Ben-Hamida , Vincent Noblet , Cristina Antal Biological Psychiatry, 2022, ⟨10.1016/j.biopsych.2022.02.013⟩ Journal articles hal-03600910v1
	The Orphan Receptor GPR88 Controls Impulsivity and Is a Risk Factor for Attention-Deficit/Hyperactivity Disorder. Sami Ben Hamida , Sarojini M. Sengupta , Ellie Clarke , Michael Mcnicholas , Eleonora Moroncini Molecular Psychiatry, 2022, ⟨10.1038/s41380-022-01738-w⟩ Journal articles hal-03779206v1
	Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies. Md Toufiqur Rahman , Ann M Decker , Lucas Laudermilk , Rangan Maitra , Weiya Ma Journal of Medicinal Chemistry, 2021, 64 (16), ⟨10.1021/acs.jmedchem.1c01075⟩ Journal articles hal-03375590v1
	Ventral striatum regulates behavioral response to ethanol and MDMA combination Sami Ben Hamida , Lucas Lecourtier , Michael Loureiro , Brigitte Cosquer , Antoine Tracqui Addiction Biology, 2020, pp.e12938. ⟨10.1111/adb.12938⟩ Journal articles hal-03015619v1
	Ventral striatum regulates behavioral response to ethanol and MDMA combination Sami Ben Hamida , Lucas Lecourtier , Michaël Loureiro , Brigitte Cosquer , Antoine Tracqui Addiction Biology, 2020, ⟨10.1111/adb.12938⟩ Journal articles hal-03037921v1
	GPCR and Alcohol-Related Behaviors in Genetically Modified Mice Jeremie Neasta , Emmanuel Darcq , Jerome Jeanblanc , Sebastien Carnicella , Sami Ben Hamida Neurotherapeutics, 2020, 17 (1, SI), pp.17-42. ⟨10.1007/s13311-019-00828-y⟩ Journal articles hal-03590705v1
	TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice Laura-Joy Boulos , Taufiq Nasseef , Michaël Mcnicholas , Anna Mechling , Laura Harsan Scientific Reports, 2019, 9 (1), ⟨10.1038/s41598-019-40622-6⟩ Journal articles hal-03682257v1
	Lack of anticipatory behavior in Gpr88 knockout mice revealed by automatized home cage phenotyping. G. Maroteaux , Tanzil Mahmud Arefin , Laura Harsan , Emmanuel Darcq , Sami Ben Hamida Genes, Brain and Behavior, 2019, ⟨10.1111/gbb.12473⟩ Journal articles hal-03600907v1
	GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior Aura Carole Meirsman , S Ben Hamida , E Clarke , A de Kerchove d'Exaerde , E Darcq eNeuro, 2019, 6 (4), pp.ENEURO.0035-19.2019. ⟨10.1523/ENEURO.0035-19.2019⟩ Journal articles hal-03677793v1
	Mu opioid receptors in the medial habenula contribute to naloxone aversion Laura-Joy Boulos , Sami Ben Hamida , Julie Bailly , Malosree Maitra , Aliza Toby Ehrlich Neuropsychopharmacology, 2019, 45 (2), pp.247-255. ⟨10.1038/s41386-019-0395-7⟩ Journal articles hal-03666931v1
	Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food Pauline Charbogne , Olivier Gardon , Elena Martín-García , Helen Keyworth , Aya Matsui Biological Psychiatry, 2017, 81 (9), pp.778-788. ⟨10.1016/j.biopsych.2016.12.022⟩ Journal articles hal-02349326v1
	Remodeling of Sensorimotor Brain Connectivity in Gpr88-Deficient Mice Tanzil Mahmud Arefin , Anna Mechling , Aura-Callia Carole Meirsman , Thomas Bienert , Neele Hubner Brain connectivity, 2017, 7 (8), pp.526-540. ⟨10.1089/brain.2017.0486⟩ Journal articles hal-03680445v1
	Mu opioid receptors in GABAergic neurons of the forebrain promote alcohol reward and drinking Sami Ben Hamida , Laura‐joy Boulos , Michael Mcnicholas , Pauline Charbogne , Brigitte Lina Kieffer Addiction Biology, 2017, 24 (1), pp.28-39. ⟨10.1111/adb.12576⟩ Journal articles hal-04322848v1
	mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors F Liu , S Laguesse , R Legastelois , N Morisot , S Ben Hamida Molecular Psychiatry, 2017, 22 (1), pp.89-101. ⟨10.1038/mp.2016.12⟩ Journal articles hal-04052852v1
	Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome Anna E. Mechling , Tanzil Arefin , Hsu-Lei Lee , Thomas Bienert , Marco Reisert Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (41), pp.11603-11608. ⟨10.1073/pnas.1601640113⟩ Journal articles hal-03653632v1
	The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors. Sami Ben Hamida , Jeremie Neasta , Amy W. Lasek , Viktor Kharazia , Mimi Zou Journal of Neuroscience, 2012, 32 (45), pp.15849-58. ⟨10.1523/JNEUROSCI.2846-12.2012⟩ Journal articles inserm-00802982v1
	Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior. Jun Wang , Sami Ben Hamida , Emmanuel Darcq , Wenheng Zhu , Stuart L. Gibb Journal of Neuroscience, 2012, 32 (43), pp.15124-32. ⟨10.1523/JNEUROSCI.2783-12.2012⟩ Journal articles inserm-00858289v1
	Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders. Jérémie Neasta , Sami Ben Hamida , Quinn Yowell , Sebastien Carnicella , Dorit Ron Proceedings of the National Academy of Sciences of the United States of America, 2010, 107 (46), pp.20093-8. ⟨10.1073/pnas.1005554107⟩ Journal articles inserm-00800434v1
	MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females J Koenig , C. Lazarus , H. Jeltsch , S Benhamida , C Riegert Pharmacology Biochemistry and Behavior, 2005, 81 (3), pp.635-644. ⟨10.1016/j.pbb.2005.04.014⟩ Journal articles hal-02347479v1

	Structural and functional signatures of chronic alcohol effects in mice Laetitia Degiorgis , Tanzil Mahmud Arefin , Sami Ben Hamida , Vincent Noblet , Maria Antal 2nd World Congress on Alcohol and Alcoholism Joint meeting of ISBRA and ESBRA, Cracovie, Poland, Jan 2022, Cracovie, Poland Conference papers hal-03926492v1
	Exposition à l’alcool chez la souris : altérations des réseaux fonctionnels et signatures structurelles régions-spécifiques Laëtitia Degiorgis , Tanzil Mahmud Arefin , Sami Ben Hamida , Vincent Noblet , Maria Antal 5ème congrès de la Société Française de Résonance Magnétique en Biologie et Médecine, Lyon, France, septembre 2021, Sep 2021, Lyon, France Conference papers hal-03799512v1
	Brain structural and functional signature of chronic alcohol effects in mice Laëtitia Degiorgis , Tanzil Mahmud Arefin , Sami Ben Hamida , Vincent Noblet , Maria Antal NeuroFrance 2021, 19-21 May, International virtual meeting, May 2021, En ligne, France Conference papers hal-03797890v1

	Effects of 3,4 methylhenedioxymethamphetamine (MDMA)-Ethanol associations on locomotor activity and body temperature in rats Jean-Christophe Cassel , Sami Ben Hamida , Julie Koenig , Hélène Jeltsch-David , Byron Jones 7e Colloque de la Société des Neurosciences, 17-20 mai 2005, Lille, May 2005, Lille, France. 2005 Conference poster hal-03264135v1
	Pubescent Long-Evans male rats are more sensitive to a high dose of 3,4 methylhenedioxymethamphetamine (MDMA) than females Christian Kelche , Julie Koenig , Hélène Jeltsch-David , Sami Ben Hamida , C Lazarus 7e Colloque de la Société des Neurosciences, May 2005, Lille, France. 2005 Conference poster hal-03187329v1

Sami Ben Hamida

Publications

Epigenetic drugs and psychedelics as emerging therapies for alcohol use disorder: insights from preclinical studies

Discovery of BI-9508, a Brain-Penetrant GPR88-Receptor-Agonist Tool Compound for In Vivo Mouse Studies

Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation

Mu opioid receptors-expressing neurons in the dorsal raphe nucleus are involved in reward processing and affective behaviors

Mu Opioid Receptor–Positive Neurons in the Dorsal Raphe Nucleus Are Impaired by Morphine Abstinence

Role of GPR88 in ethanol drinking: A new pharmacological target

The GPR88 agonist RTI-13951-33 reduces alcohol drinking and seeking in mice

Translational structural and functional signatures of chronic alcohol effects in mice

The Orphan Receptor GPR88 Controls Impulsivity and Is a Risk Factor for Attention-Deficit/Hyperactivity Disorder.

Evaluation of Amide Bioisosteres Leading to 1,2,3-Triazole Containing Compounds as GPR88 Agonists: Design, Synthesis, and Structure-Activity Relationship Studies.

Ventral striatum regulates behavioral response to ethanol and MDMA combination

Ventral striatum regulates behavioral response to ethanol and MDMA combination

GPCR and Alcohol-Related Behaviors in Genetically Modified Mice

TouchScreen-based phenotyping: altered stimulus/reward association and lower perseveration to gain a reward in mu opioid receptor knockout mice

Lack of anticipatory behavior in Gpr88 knockout mice revealed by automatized home cage phenotyping.

GPR88 in D1R-Type and D2R-Type Medium Spiny Neurons Differentially Regulates Affective and Motor Behavior

Mu opioid receptors in the medial habenula contribute to naloxone aversion

Mu Opioid Receptors in Gamma-Aminobutyric Acidergic Forebrain Neurons Moderate Motivation for Heroin and Palatable Food

Remodeling of Sensorimotor Brain Connectivity in Gpr88-Deficient Mice

Mu opioid receptors in GABAergic neurons of the forebrain promote alcohol reward and drinking

mTORC1-dependent translation of collapsin response mediator protein-2 drives neuroadaptations underlying excessive alcohol-drinking behaviors

Deletion of the mu opioid receptor gene in mice reshapes the reward–aversion connectome

The small G protein H-Ras in the mesolimbic system is a molecular gateway to alcohol-seeking and excessive drinking behaviors.

Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior.

Role for mammalian target of rapamycin complex 1 signaling in neuroadaptations underlying alcohol-related disorders.

MDMA (ecstasy) effects in pubescent rats: Males are more sensitive than females

Structural and functional signatures of chronic alcohol effects in mice

Exposition à l’alcool chez la souris : altérations des réseaux fonctionnels et signatures structurelles régions-spécifiques

Brain structural and functional signature of chronic alcohol effects in mice

Effects of 3,4 methylhenedioxymethamphetamine (MDMA)-Ethanol associations on locomotor activity and body temperature in rats

Pubescent Long-Evans male rats are more sensitive to a high dose of 3,4 methylhenedioxymethamphetamine (MDMA) than females