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Samuel Valable

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samuel valable,hypoxia

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Functional impact of oxygen-saturated zeolite nanoparticles on macrophages in the context of glioblastoma: an in vitro and in vivo study

Aurélie E Ferre , Sarah Komaty , C Hélaine , Clément Anfray , Sajjad Ghojavand
Colloids and Surfaces B: Biointerfaces, In press, 230, ⟨10.1016/j.colsurfb.2023.113524⟩
Journal articles hal-04190367v1
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Magnetic resonance imaging of hypoxia in acute stroke: a cross‐validation study against FMISO‐positron emission tomography

Valable Samuel , Jérôme Toutain , Didier Divoux , Laurent Chazalviel , Aurélien Corroyer-Dulmont
NMR in Biomedicine, 2023, 36 (3), pp.e4858. ⟨10.1002/nbm.4858⟩
Journal articles hal-03831642v1
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The Impact of Resampling and Denoising Deep Learning Algorithms on Radiomics in Brain Metastases MRI

Ilyass Moummad , Cyril Jaudet , Alexis Lechervy , Samuel Valable , Charlotte Raboutet
Cancers, 2022, 14 (1), pp.36. ⟨10.3390/cancers14010036⟩
Journal articles hal-03519111v1
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First-in-Man Noninvasive Initial Diagnostic Approach of Primary CNS Lymphoma Versus Glioblastoma Using PET With 18F-Fludarabine and l-[methyl-11C]Methionine

Andrey Postnov , Jérôme Toutain , Igor Pronin , Valable Samuel , Fabienne Gourand
Clinical Nuclear Medicine, 2022, 47 (8), pp.699-706. ⟨10.1097/RLU.0000000000004238⟩
Journal articles hal-03672116v1
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Internalization study of nanosized zeolite crystals in human glioblastoma cells

C Hélaine , Hayriye Özçelik , Sarah Komaty , Abdallah Amedlous , Sajjad Ghojavand
Colloids and Surfaces B: Biointerfaces, 2022, 218, pp.112732. ⟨10.1016/j.colsurfb.2022.112732⟩
Journal articles hal-03752239v1
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Simultaneous mapping of vasculature, hypoxia and proliferation using DSC-MRI, 18F-FMISO PET, and 18F-FLT PET in relation to contrast enhancement in newly diagnosed glioblastoma

Solène Collet , Jean Sébastien Guillamo , David Hassanein Berro , Ararat Chakhoyan , Jean-Marc Constans
Journal of Nuclear Medicine, 2021, 62 (10), pp.1349-1356. ⟨10.2967/jnumed.120.249524⟩
Journal articles hal-03123047v1
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Radioimmunotherapy for Brain Metastases: The Potential for Inflammation as a Target of Choice

Aurélien Corroyer-Dulmont , Cyril Jaudet , Anne-Marie Frelin , Jade Fantin , Kathleen Weyts
Frontiers in Oncology, 2021, 11, pp.714514. ⟨10.3389/fonc.2021.714514⟩
Journal articles hal-03335353v1
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The Reactive Species Interactome in the brain

Elise Malard , Valable Samuel , Myriam Bernaudin , Elodie A. Pérès , Laurent Chatre
Antioxidants and Redox Signaling, 2021, 35 (14), pp.1176-1206. ⟨10.1089/ars.2020.8238⟩
Journal articles hal-03346396v1
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Multimodal evaluation of hypoxia in brain metastases of lung cancer and interest of hypoxia image-guided radiotherapy

Aurélien Corroyer-Dulmont , Valable Samuel , Jade Fantin , Laurent Chatre , Jérôme Toutain
Scientific Reports, 2021, 11 (1), pp.11239. ⟨10.1038/s41598-021-90662-0⟩
Journal articles hal-03244249v1
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Nanosized zeolites as a gas delivery platform in a glioblastoma model

Clement Anfray , Sarah Komaty , Aurélien Corroyer-Dulmont , Moussa Zaarour , Charly Hélaine
Biomaterials, 2020, 257, pp.120249. ⟨10.1016/j.biomaterials.2020.120249⟩
Journal articles hal-02912573v1
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The role of hypoxia and SRC tyrosine kinase in glioblastoma invasiveness and radioresistance

Filippo Torrisi , Nunzio Vicario , Federica Spitale , Francesco Cammarata , Luigi Minafra
Cancers, 2020, 12 (10), pp.2860. ⟨10.3390/cancers12102860⟩
Journal articles hal-02989744v1
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Incorporation of trivalent cations in NaX zeolite nanocrystals for the adsorption of O 2 in the presence of CO 2

Sarah Komaty , Ayoub Daouli , Michael Badawi , Clément Anfray , Moussa Zaarour
Physical Chemistry Chemical Physics, 2020, 22 (18), pp.9934-9942. ⟨10.1039/D0CP00111B⟩
Journal articles hal-03027929v1
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Ruthenium tris(2,2′-bipyridyl) complex encapsulated in nanosized faujasite zeolite as intracellular localization tracer

Sarah Komaty , Hayriye Özçelik , Moussa Zaarour , Aurélie Ferré , Samuel Valable
Journal of Colloid and Interface Science, 2020, 581 (Part B), pp.919-927. ⟨10.1016/j.jcis.2020.08.117⟩
Journal articles hal-02935419v1
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Impact of Hypoxia on Carbon Ion Therapy in Glioblastoma Cells: Modulation by LET and Hypoxia-Dependent Genes

Samuel Valable , Aurélie Gérault , Gaelle Lambert , Marine Leblond , Clement Anfray
Cancers, 2020, 12 (8), pp.2019. ⟨10.3390/cancers12082019⟩
Journal articles hal-02912590v1
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SRC Tyrosine Kinase Inhibitor and X-rays Combined Effect on Glioblastoma Cell Lines

Filippo Torrisi , Luigi Minafra , Francesco Cammarata , Gaetano Savoca , Marco Calvaruso
International Journal of Molecular Sciences, 2020, 21 (11), pp.3917. ⟨10.3390/ijms21113917⟩
Journal articles hal-02861596v1
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Radionuclide spatial distribution and dose deposition for in vitro assessments of $^{212}$Pb-alphaVCAM-1 targeted alpha therapy

Anne-Marie Frelin-Labalme , Thomas Roger , Nadia Falzone , Boon Quan Lee , Nicola R. Sibson
Medical Physics, 2020, 47, pp.1317-1326. ⟨10.1002/mp.13969⟩
Journal articles hal-02409608v1
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Imaging issues specific to hadrontherapy (proton, carbon, helium therapy and other charged particles) for radiotherapy planning, setup, dose monitoring and tissue response assessment

J. Thariat , J. Herault , A. Beddok , L. Feuvret , D. Dauvergne
Cancer/Radiothérapie, 2020, 24 (5), pp.429-436. ⟨10.1016/j.canrad.2020.01.010⟩
Journal articles hal-02535459v1
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Hadrontherapy Interactions in Molecular and Cellular Biology

Juliette Thariat , Samuel Valable , Carine Laurent , Siamak Haghdoost , Elodie A. Pérès
International Journal of Molecular Sciences, 2020, 21 (1), pp.133. ⟨10.3390/ijms21010133⟩
Journal articles hal-02429129v1
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Angiopoietin-2 Combined with Radiochemotherapy Impedes Glioblastoma Recurrence by Acting in an Autocrine and Paracrine Manner: A Preclinical Study

Charly Hélaine , Aurélie Ferré , Marine Leblond , Elodie Pérès , Myriam Bernaudin
Cancers, 2020, 12 (12), pp.3585. ⟨10.3390/cancers12123585⟩
Journal articles hal-03082539v1
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VCAM-1 Targeted Alpha-Particle Therapy for Early Brain Metastases

Aurélien Corroyer-Dulmont , Samuel Valable , Nadia Falzone , Anne-Marie Frelin-Labalme , Ole Tietz
Neuro-Oncology, 2019, 22 (3), pp.357-368. ⟨10.1093/neuonc/noz169⟩
Journal articles hal-02346582v1

Copper exchanged FAU nanozeolite as non-toxic nitric oxide and carbon dioxide gas carrier

Kamila Goldyn , Clément Anfray , Sarah Komaty , Valerie Ruaux , Charly Hélaine
Microporous and Mesoporous Materials, 2019, Special Issue dedicated to the 65 birthday of Prof. Wieslaw J. Roth, 280, pp.271-276. ⟨10.1016/j.micromeso.2019.02.022⟩
Journal articles hal-02086878v1

Prostate cancer heterogeneity: texture analysis score based on multiple magnetic resonance imaging sequences for detection, stratification and selection of lesions at time of biopsy.

Clément Orczyk , Arnauld Villers , Henry Rusinek , Vincent Lepennec , Celine Bazille
BJU International, 2019, 124 (1), pp.76-86. ⟨10.1111/bju.14603⟩
Journal articles hal-02090243v1
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Hypoxia Imaging and Adaptive Radiotherapy: A State-of-the-Art Approach in the Management of Glioma

Michael Gérard , Aurélien Corroyer-Dulmont , Paul Lesueur , Solène Collet , Michel Chérel
Frontiers in Medicine, 2019, 6:117, ⟨10.3389/fmed.2019.00117⟩
Journal articles hal-02153761v1
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Potential for nuclear medicine therapy for glioblastoma treatment

Clément Bailly , Aurélien Vidal , Coralie Bonnemaire , Françoise Kraeber-Bodéré , Michel Chérel
Frontiers in Pharmacology, 2019, 10, pp.772. ⟨10.3389/fphar.2019.00772⟩
Journal articles hal-02163322v1
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Comparison between MRI-derived ADC maps and 18FLT-PET in pre-operative glioblastoma

David Hassanein Berro , Solène Collet , Jean-Marc Constans , Louisa Barré , Jean-Michel Derlon
American Journal of Neuroradiology, 2019, 46 (6), pp.359-366. ⟨10.1016/j.neurad.2019.05.011⟩
Journal articles hal-02264986v1

64Cu-ATSM/64Cu-Cl2 and their relationship to hypoxia in glioblastoma: a preclinical study

Elodie A. Pérès , Toutain Jérôme , Louis-Paul Paty , Didier Divoux , Méziane Ibazizène
EJNMMI Research, 2019, 9 (114), ⟨10.1186/s13550-019-0586-6⟩
Journal articles hal-02409461v1

La radiothérapie modifie l'inflammation tumorale

Valable Samuel
Une année avec le CNRS en Normandie, 2018, pp.16
Journal articles hal-02285007v1

[ 18 F]Fludarabine-PET as a promising tool for differentiating CNS lymphoma and glioblastoma: Comparative analysis with [ 18 F]FDG in human xenograft models

Narinée Hovhannisyan , Fabien Fillesoye , Stéphane Guillouet , Méziane Ibazizene , Jérôme Toutain
Theranostics, 2018, 8 (16), pp.4563-4573. ⟨10.7150/thno.26754⟩
Journal articles hal-02006576v1

A Facile Route toward the Increase of Oxygen Content in Nanosized Zeolite by Insertion of Cerium and Fluorinated Compounds

Sarah Komaty , Clement Anfray , Moussa Zaarour , Hussein Awala , Valérie Ruaux
Molecules, 2018, 23 (2), pp.37. ⟨10.3390/molecules23020037⟩
Journal articles hal-02410323v1

Encapsulation of fluorescein into nanozeolites L and Y

M. Łukarska , A. Jankowska , J. Gapiński , S. Valable , C. Anfray
Microporous and Mesoporous Materials, 2018, 260, pp.70--75. ⟨10.1016/j.micromeso.2017.10.040⟩
Journal articles hal-01840129v1

Améliorer l'imagerie de l'oxygénation pour optimiser les thérapies en cancérologies

Valable Samuel
La Revue parlementaire, 2018, pp.12
Journal articles hal-02284998v1

A heparan sulfate-based matrix therapy reduces brain damage and enhances functional recovery following stroke

Yacine Khelif , Jérôme Toutain , Marie-Sophie Quittet , Sandrine Chantepie , Xavier Laffray
Theranostics, 2018, 8 (21), pp.5814-5827. ⟨10.7150/thno.28252⟩
Journal articles hal-02018014v1

In vivo relationship between hypoxia and angiogenesis in human glioblastoma: a multimodal imaging study.

K Ferreira da Ponte , Dh Berro , S Collet , Jm Constans , E Emery
Journal of Nuclear Medicine, 2017, 10, 58, pp.1574-1579. ⟨10.2967/jnumed.116.188557⟩
Journal articles hal-01575547v1

Synthesis of fluorescein by a ship-in-a-bottle method in different zeolites

M. Łukarska , A. Jankowska , J. Gapiński , S. Valable , C. Anfray
New Journal of Chemistry, 2017, 41 (18), pp.9969--9976. ⟨10.1039/C7NJ01427A⟩
Journal articles hal-01840151v1

Carbogen-induced increases in tumor oxygenation depend on the vascular status of the tumor: A multiparametric MRI study in two rat glioblastoma models.

A Chakhoyan , A Corroyer-Dulmont , M.M. Leblond , A Gérault , J Toutain
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (6), pp.2270-2282. ⟨10.1177/0271678X16663947⟩
Journal articles hal-01575557v1

Acute Toxicity of Silver Free and Encapsulated in Nanosized Zeolite for Eukaryotic Cells

Clement Anfray , Biao Dong , Sarah Komaty , Svetlana Mintova , Samuel Valable
ACS Applied Materials & Interfaces, 2017, 9 (16), pp.13849-13854. ⟨10.1021/acsami.7b00265⟩
Journal articles hal-02410404v1

Les zéolithes de taille nanométrique comme outil théranostique pour les tumeurs cérébrales ?

Valable Samuel
Une année avec le CNRS en Normandie, 2017, pp.15
Journal articles hal-02285012v1

3D Registration of mpMRI for Assessment of Prostate Cancer Focal Therapy

Clément Orczyk , Andrew Rosenkrantz , Artem Mikheev , Arnauld Villers , Myriam Bernaudin
Academic Radiology, 2017, 24 (12), pp.1544-1555. ⟨10.1016/j.acra.2017.06.010⟩
Journal articles hal-02006264v1

M2 macrophages are more resistant than M1 macrophages following radiation therapy in the context of glioblastoma

Marine Leblond , Elodie A. Pérès , Charly Hélaine , Aurélie Gérault , Damien Moulin
Oncotarget, 2017, 8 (42), pp.72597-72612. ⟨10.18632/oncotarget.19994⟩
Journal articles hal-02100869v1

[18F]-FMISO PET study of hypoxia in gliomas before surgery: correlation with molecular markers of hypoxia and angiogenesis.

L Bekaert , S Valable , E Lechapt-Zalcman , K Ponte , S Collet
European Journal of Nuclear Medicine and Molecular Imaging, 2017, 44 (8), pp.1383-1392. ⟨10.1007/s00259-017-3677-5⟩
Journal articles hal-01575007v1

FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas

Ararat Chakhoyan , Jean-Sébastien Guillamo , Solène Collet , François Kauffmann , Nicolas Delcroix
Scientific Reports, 2017, 7 (1), ⟨10.1038/s41598-017-08646-y⟩
Journal articles hal-02043459v1

Imaging of brain oxygenation with magnetic resonance imaging : A validation with positron emission tomography in the healthy and tumoural brain.

S Valable , A Corroyer-Dulmont , A Chakhoyan , L Durand , J Toutain
Journal of Cerebral Blood Flow and Metabolism, 2017, 37 (7), pp.2584-2597. ⟨10.1177/0271678X16671965⟩
Journal articles hal-01575065v1

Long-Lasting Effects of Chronic Intermittent Alcohol Exposure in Adolescent Mice on Object Recognition and Hippocampal Neuronal Activity.

G Beaudet , S Valable , J Bourgine , V Lelong-Boulouard , L Lanfumey
Alcoholism: Clinical and Experimental Research, 2016, 40 (12), pp.2591-2603. ⟨10.1111/acer.13256⟩
Journal articles hal-01576066v1

Multimodal imaging based on MRI and PET reveals [(18)F]FLT PET as a specific and early indicator of treatment efficacy in a preclinical model of recurrent glioblastoma

A Corroyer-Dulmont , Elodie A. Pérès , An Gérault , A Savina , F Bouquet
European Journal of Nuclear Medicine and Molecular Imaging, 2016, 43 (4), pp.682-694. ⟨10.1007/s00259-015-3225-0⟩
Journal articles hal-01575614v1

Hypoxia induces macrophage polarization and re-education toward an M2 phenotype in U87 and U251 glioblastoma models.

M.M. Leblond , An Gérault , A Corroyer-Dulmont , Et Mackenzie , E Petit
OncoImmunology, 2016, 5 (1), pp.e1056442. ⟨10.1080/2162402X.2015.1056442⟩
Journal articles hal-01576135v1

Iron loaded EMT nanosized zeolite with high affinity towards CO 2 and NO

Veselina Georgieva , Clément Anfray , Richard Retoux , Valentin Valtchev , Samuel Valable
Microporous and Mesoporous Materials, 2016, 232, pp.256-263. ⟨10.1016/j.micromeso.2016.06.015⟩
Journal articles hal-02402344v1

Neuronal and Glial Changes in Rat Hippocampal Formation afterCholinergic Deafferentation

Veronique Paban , Samuel Valable , Nathalie Baril , Valerie Gilbert , Caroline Chambon
Journal of Biomolecular Research & Therapeutics, 2016, 4, 5, ⟨10.4172/2167-7956.1000147⟩
Journal articles hal-01433055v1

Synthesis and encapsulation of fluorescein in zeolite Y

Małgorzata Łukarska , Aldona Jankowska , Jacek Gapiński , Samuel Valable , Clement Anfray
Microporous and Mesoporous Materials, 2016, 236, pp.79-84. ⟨10.1016/j.micromeso.2016.02.043⟩
Journal articles hal-02410457v1

[(18)F]-fluoro-L-thymidine PET and advanced MRI for preoperative grading of gliomas

S Collet , S Valable , Jm Constans , E Lechapt-Zalcman , S Roussel
Neuroimage-Clinical, 2015, 8, pp.448-54. ⟨10.1016/j.nicl.2015.05.012⟩
Journal articles hal-01585022v1

Imaging Modalities to Assess Oxygen Status in Glioblastoma

A Corroyer-Dulmont , A Chakhoyan , S Collet , L Durand , Et Mackenzie
Frontiers in Medicine, 2015, 2, pp.57. ⟨10.3389/fmed.2015.00057⟩
Journal articles hal-01587314v1
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Imaging modalities to assess oxygen status in glioblastoma

Aurélien Corroyer-Dulmont , Ararat Chakhoyan , Solène Collet , Lucile Durand , Eric T. Mackenzie
Frontiers in Medicine, 2015, 2, pp.57. ⟨10.3389/fmed.2015.00057⟩
Journal articles hal-02292354v1

Silencing erythropoietin receptor on glioma cells reinforces efficacy of temozolomide and X-rays through senescence and mitotic catastrophe

Elodie A. Pérès , An Gérault , S Valable , S Roussel , J Toutain
Oncotarget, 2015, 6 (4), pp.2101-19. ⟨10.18632/oncotarget.2937⟩
Journal articles hal-01576268v1

Chronic arterial hypertension impedes glioma growth: a multiparametric MRI study in the rat.

Al Letourneur , S Roussel , M Bernaudin , F Fillesoye , J Toutain
Hypertension Research, 2015, 38 ((11)), pp.723-32. ⟨10.1038/hr.2015.66⟩
Journal articles hal-01587404v1

Suivi oncologique post thérapie focale du cancer de prostate : définition précise de la cible résiduelle par une nouvelle méthode de recalage-fusion d’image déformable en 3D

C. Orczyk , A. Rosenkrantz , H. Rusinek , J. Le Nobin , A. Mikheev
Progrès en Urologie, 2014, 24 (13), ⟨10.1016/j.purol.2014.08.169⟩
Journal articles hal-01626654v1
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IDH1R132H Mutation Increases U87 Glioma Cell Sensitivity to Radiation Therapy in Hypoxia

Xiao-Wei Wang , Marianne Labussière , Samuel Valable , Elodie A. Pérès , Jean-Sébastien Guillamo
BioMed Research International , 2014, 2014, pp.198697. ⟨10.1155/2014/198697⟩
Journal articles hal-01308328v1

Human Leukocyte Antigen-G Is Frequently Expressed in Glioblastoma and May Be Induced in Vitro by Combined 5-Aza-2′-Deoxycytidine and Interferon-γ Treatments

Isabela Wastowski , Renata T. Simões , Layale Yaghi , Eduardo A. Donadi , João T. Pancoto
American Journal of Pathology, 2013, 182 (2), pp.540 - 552. ⟨10.1016/j.ajpath.2012.10.021⟩
Journal articles hal-01664738v1

Noninvasive assessment of hypoxia with 3-[18F]-fluoro-1-(2-nitro-1-imidazolyl)-2-propanol ([18F]-FMISO): a PET study in two experimental models of human glioma

Aurélien Corroyer-Dulmont , Elodie A. Pérès , Edwige Petit , Lucile Durand , Léna Marteau
Biological Chemistry, 2013, 394 (4), ⟨10.1515/hsz-2012-0318⟩
Journal articles hal-01660598v1
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In vivo imaging of vessel diameter, size, and density: a comparative study between MRI and histology.

Benjamin Lemasson , Samuel Valable , Régine Farion , Alexandre Krainik , Chantal Rémy
Magnetic Resonance in Medicine, 2013, 69 (1), pp.18-26. ⟨10.1002/mrm.24218⟩
Journal articles inserm-00861168v1
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Detection of glioblastoma response to temozolomide combined with bevacizumab based on µMRI and µPET imaging reveals [$^{18}$F]-fluoro-L-thymidine as an early and robust predictive marker for treatment efficacy

Aurélien Corroyer-Dulmont , Elodie A. Pérès , Edwige Petit , Jean-Sébastien Guillamo , Nathalie Varoqueaux
Neuro-Oncology, 2013, 15 (1), pp.41 - 56. ⟨10.1093/neuonc/nos260⟩
Journal articles hal-01655989v1
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Diffusion tensor imaging of diffuse axonal injury in a rat brain trauma model.

Yohan van de Looij , Franck Mauconduit , Marine Beaumont , Samuel Valable , Régine Farion
NMR in Biomedicine, 2012, 25 (1), pp.93-103. ⟨10.1002/nbm.1721⟩
Journal articles inserm-00755173v1

Inactivation of the HIF-1 /PDK3 Signaling Axis Drives Melanoma toward Mitochondrial Oxidative Metabolism and Potentiates the Therapeutic Activity of Pro-Oxidants

J. Kluza , P. Corazao-Rozas , Y. Touil , M. Jendoubi , C. Maire
Cancer Research, 2012, 72 (19), pp.5035 - 5047. ⟨10.1158/0008-5472.CAN-12-0979⟩
Journal articles hal-01853694v1
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Magnetic resonance imaging and fluorescence labeling of clinical-grade mesenchymal stem cells without impacting their phenotype: study in a rat model of stroke.

Olivier Detante , Samuel Valable , Florence de Fraipont , Emmanuelle Grillon , Emmanuel Luc Barbier
Stem Cells Transl Med, 2012, 1 (4), pp.333-41. ⟨10.5966/sctm.2011-0043⟩
Journal articles inserm-00760939v1

Angiopoietin-2 is Vasoprotective in the Acute Phase of Cerebral Ischemia

Léna Marteau , Samuel Valable , Didier Divoux , Simon A Roussel , Omar Touzani
Journal of Cerebral Blood Flow and Metabolism, 2012, 33 (3), pp.389 - 395. ⟨10.1038/jcbfm.2012.178⟩
Journal articles hal-01660588v1
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Reduced brain edema and functional deficits after treatment of diffuse traumatic brain injury by carbamylated erythropoietin derivative.

Pierre Bouzat , Gilles Francony , Sébastien Thomas , Samuel Valable , Franck Mauconduit
Critical Care Medicine, 2011, 39 (9), pp.2099-105. ⟨10.1097/CCM.0b013e31821cb7b2⟩
Journal articles inserm-00658345v1

Angiopoietin-2 Regulates Cortical Neurogenesis in the Developing Telencephalon

Léna Marteau , Emilie Pacary , Samuel Valable , Myriam Bernaudin , François Guillemot
Cerebral Cortex, 2011, 21, pp.1695 - 1702. ⟨10.1093/cercor/bhq243⟩
Journal articles hal-01768931v1
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The impact of erythropoietin on short-term changes in phosphorylation of brain protein kinases in a rat model of traumatic brain injury.

Samuel Valable , Gilles Francony , Pierre Bouzat , Marie-Cécile Fevre , Nouara Mahious
Journal of Cerebral Blood Flow and Metabolism, 2010, 30 (2), pp.361-9. ⟨10.1038/jcbfm.2009.222⟩
Journal articles inserm-00517172v1

Autocrine and paracrine angiopoietin 1/Tie-2 signaling promotes muscle satellite cell self-renewal

Rana Abou-Khalil , Fabien Le Grand , Giorgia Pallafacchina , Samuel Valable , François-Jérôme Authier
Cell Stem Cell, 2009, 5 (3), pp.298--309. ⟨10.1016/j.stem.2009.06.001⟩
Journal articles hal-02142762v1

The impact of erythropoietin on short-term changes in phosphorylation of brain protein kinases in a rat model of traumatic brain injury

Samuel Valable , Gilles Francony , Pierre Bouzat , Marie-Cécile Fevre , Nouara Mahious
Journal of Cerebral Blood Flow and Metabolism, 2009, 30, pp.361-369. ⟨10.1038/jcbfm.2009.222⟩
Journal articles hal-00866969v1

Autocrine and Paracrine Angiopoietin 1/Tie-2 Signaling Promotes Muscle Satellite Cell Self-Renewal

Rana Abou-Khalil , Fabien Le Grand , Giorgia Pallafacchina , Samuel Valable , François-Jérôme Authier
Cell Stem Cell, 2009, 5 (3), pp.298-309. ⟨10.1016/j.stem.2009.06.001⟩
Journal articles hal-03184334v1
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In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma.

Samuel Valable , Emmanuel L Barbier , Myriam Bernaudin , Simon Roussel , Christoph Segebarth
NeuroImage, 2008, 40 (2), pp.973-83
Journal articles inserm-00536177v1
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Assessment of blood volume, vessel size, and the expression of angiogenic factors in two rat glioma models: a longitudinal in vivo and ex vivo study.

Samuel Valable , Benjamin Lemasson , Régine Farion , Marine Beaumont , Christoph Segebarth
NMR in Biomedicine, 2008, 21 (10), pp.1043-56. ⟨10.1002/nbm.1278⟩
Journal articles inserm-00381408v1

In vivo MRI tracking of exogenous monocytes/macrophages targeting brain tumors in a rat model of glioma.

Samuel Valable , Emmanuel L Barbier , Myriam Bernaudin , Simon Roussel , Christoph Segebarth
NeuroImage, 2007, 37 Suppl 1, pp.S47-58. ⟨10.1016/j.neuroimage.2007.05.041⟩
Journal articles hal-00178542v1

FLIP(L) protects neurons against in vivo ischemia and in vitro glucose deprivation-induced cell death.

Era Taoufik , Samuel Valable , Georg J Müller , Michael L Roberts , Didier Divoux
Journal of Neuroscience, 2007, 27 (25), pp.6633-46. ⟨10.1523/JNEUROSCI.1091-07.2007⟩
Journal articles hal-00178529v1

Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

Thomas Freret , Samuel Valable , Laurent Chazalviel , Romaric Saulnier , Eric T Mackenzie
European Journal of Neuroscience, 2006, 23 (7), pp.1757-65. ⟨10.1111/j.1460-9568.2006.04699.x⟩
Journal articles hal-00865370v1

Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.

T. Freret , S. Valable , L. Chazalviel , R. Saulnier , E.T. Mackenzie
European Journal of Neuroscience, 2006, 23, pp.1757-1765
Journal articles hal-00023477v1

Synergistic effects of cocl2 and rock inhibition on mesenchymal stem cell differentiation into neuron-like cells

E. Pacary , S. Legros , S. Valable , P. Duchatelle , M. Lecocq
Journal of Cell Science, 2006, 119, pp.2667-2678
Journal articles hal-00068390v1

Oxygen glucose deprivation switches the transport of tPA across the blood-brain barrier from an LRP-dependent to an increased LRP-independent process

Karim Benchenane , Vincent Berezowski , Monica Fernandez-Monreal , Julien Brillault , Samuel Valable
Stroke, 2005, p. 1059-1064
Journal articles hal-00542010v1

VEGF-induced BBB permeability is associated with an MMP-9 activity increase in cerebral ischemia: both effects decreased by Ang-1

Samuel Valable , Joan Montaner , Anita Bellail , Vincent Berezowski , Julien Brillault
Journal of Cerebral Blood Flow and Metabolism, 2005, p. 1-14
Journal articles hal-00542804v1

Angiopoietin-1-induced PI3-kinase activation prevents neuronal apoptosis

S. Valable , A. Bellail , S. Lesné , G. Liot , E. Mackenzie
FASEB Journal, 2003, 17 (3), pp.443-445. ⟨10.1096/fj.02-0372fje⟩
Journal articles hal-02472824v1

Zéolithes et applications biomédicales (conférence grand public)

Valable Samuel
Soirée Annuelle Association EPOPEA, Oct 2022, CAEN, France
Conference papers hal-04000988v1

Tumor sensitization and reoxygenation with gadolinium-containing zeolites nanocrystals: a new theranostic strategy for glioblastoma

Valable Samuel
OncoTrans, Nov 2022, NANCY, France
Conference papers hal-03990640v1

Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat

Gwenn Ropars , Fatima-Azzahra Dwiri , Brunaud Carole , Jérôme Toutain , Laurent Chatre
Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Jul 2022, Paris, France
Conference papers hal-03760839v1

MRI biomarkers for the detection of radiation-induced brain injury associated to cognitive deficits

G. Ropars , Fatima-Azzahra Dwiri , R. Le Gal , Jérôme Toutain , Brunaud Carole
5th Conference on Small Animal Precision Image-Guided Radiotherapy, Mar 2022, Munich, Germany
Conference papers hal-03643196v1

Etude préclinique de l’hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ?

Jade Fantin , Jérôme Toutain , Aurélien Corroyer-Dulmont , Elodie A. Pérès , Mickael Bourgeois
14èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2022, Deauville, France
Conference papers hal-03699264v1

Comparative preclinical study of the effect of proton therapy versus conventional radiotherapy on circulating leukocytes in a context of brain tumour irradiation

Julie Coupey , Thao Nguyen Pham , Jérôme Toutain , Erika Hue , C Hélaine
5th Conference on Small Animal Precision Image-Guided Radiotherapy, Mar 2022, Munich, Germany
Conference papers hal-03618448v1

Intérêt des biomarqueurs d'imagerie pour guider les thérapies dans les gliomes de haut grade

Valable Samuel
Les Translationnelles en Oncologie 2022 sur les tumeurs cérébrales, Cancéropole Nord-Ouest, Dec 2022, Caen (FR), France
Conference papers hal-03990610v1

The whole-brain irradiation induces skeletal muscle damage in the rat

Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel
Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Jul 2022, Paris, France
Conference papers hal-03760852v1

Hemispheric versus whole-brain irradiation induced neurotoxicity: longitudinal studies in the rat

Fatima-Azzahra Dwiri , Gwenn Ropars , Julie Bécam , Carole Brunaud , L Chazalviel
Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Cancéropôle Nord Ouest, Jul 2022, Paris, France
Conference papers hal-04192029v1

Etude préclinique de l'hypoxie tumorale par imagerie multimodale en IRM et TEP dans les métastases cérébrales : intérêt du [64Cu]-ATSM ?

Jade Fantin , Jérôme Toutain , Aurélien Corroyer-Dulmont , Elodie A. Pérès , Mickael Bourgeois
2ème Rencontre Scientifique sur les tumeurs cérébrales "Détecter et Cibler la Récidive", Feb 2022, e-congrès, France
Conference papers hal-03699245v1

HadronThérapie

Valable Samuel
Rotary Club, Mar 2022, Caen, France
Conference papers hal-03990690v1

Imagerie médicale et tumeurs: exemple de recherche translationnelle

Valable Samuel
Assemblée Générale de l'association CCJV, Sep 2022, Caen, France
Conference papers hal-03990761v1

Preclinical model of radiation induced-neurotoxicity: longitudinal and multiparametric evaluation of tissue injury and cognitive deficits in the rat

Gwenn Ropars , Fatima-Azzahra Dwiri , Carole Brunaud , Jérôme Toutain , Laurent Chatre
1er congrès de la Société Française de Biologie des Radiations, Nov 2022, Agay-Saint Raphaël, France
Conference papers hal-04192035v1

BRAINTEL : Modification du signal IRM chez les patients porteurs de tumeurs bénignes du cerveau et des méninges traitées par proton-thérapie : Impact du TEL et de la dose biologique reçue

Paul Lesueur , Thomas Tessonier , Brunaud Carole , Cyril Moignier , Anthony Vela
14èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2022, Deauville, France
Conference papers hal-03699279v1

The physical activity attenuates the brain irradiation-induced cerebral and skeletal muscle injuries in the adult rat

Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel
5th Conference on Small Animal Precision Image-Guided Radiotherapy, Mar 2022, Munich, Germany
Conference papers hal-03618436v1

De l’oxygène pour les tumeurs cérébrales : un nouvel espoir ? (Grand public)

Valable Samuel
Fête de la science, CYCERON, Oct 2022, Caen, France
Conference papers hal-03990771v1

Mutiparametric and multiscale assessment of the brain reactions to conventional and recently developed radiation therapies

Valable Samuel
Cancer and Cancer Treatments on Cognitive Functions: At the Era of Comprehensive Mechanisms, Jul 2022, Paris, France
Conference papers hal-03761506v1

Biomedical applications of zeolites

Valable Samuel
Groupe Français des Zéolithes, Mar 2022, Lou Capitelle, France
Conference papers hal-03643282v1

Intérêt de l’hadronthérapie pour favoriser l’immunité anti-tumorale dans un contexte de radiothérapie cérébrale ?

Valable Samuel
LABEX PRIMES, Jul 2022, Lyon, France
Conference papers hal-03761500v1

Hypoxie et tumeurs cérébrales : intérêt des biomarqueurs d’imagerie pour guider les traitements ?

Valable Samuel
Réunion annuelle de la SCMC, Jun 2022, Paris, France
Conference papers hal-03761492v1

Comparative study of proton versus X-rays on circulating leukocytes in a context of brain irradiation: a preclinical study

Samuel Valable , Julie Coupey , Thao Nguyen Pham , Jérôme Toutain , V. Ivanova
Premier congrès de radiobiologie de la SFBR, SFBR, Nov 2022, Agay-Saint Raphaël, France
Conference papers hal-03845697v1

Impact d’un algorithme de machine learning de resampling sur les radiomiques en IRM

I. Moummad , C. Jaudet , A. Lechervy , Valable Samuel , C. Raboutet
13èmes journées scientifiques du Cancéropôle Nord-Ouest, Oct 2021, Deauville, France
Conference papers hal-03467508v1

Conférence : "De l’oxygène pour les tumeurs cérébrales : un nouvel espoir ?"

Valable Samuel
Fête de la Science (Plateforme CYCERON), Oct 2021, Caen, France
Conference papers hal-03561918v1

L’activité physique réduit la cachexie observée après irradiation cérébrale chez le rat

Julie Bécam , Gwenn Ropars , Fatima-Azzahra Dwiri , Jérôme Toutain , Laurent Chazalviel
13èmes journées scientifiques du Cancéropôle Nord-Ouest, Oct 2021, Deauville, France
Conference papers hal-03467478v1

Caractérisation de l’hypoxie et stratégies pour lever la radiorésistance dans les glioblastomes et les métastases cérébrales

Myriam Bernaudin , Hassanein Berro David , Solène Collet , Aurélien Corroyer-Dulmont , Marine Leblond M
1ere e-Rencontre Scientifique sur les Tumeurs Cérébrales (CNO), Jun 2021, e-congrès, France
Conference papers hal-03284544v1

Detection and strategies to overcome hypoxia-induced radioresistance in glioblastoma

Valable Samuel
New approaches to tackle Glioblastoma resistance, Nov 2021, Illkirch, France
Conference papers hal-03561724v1

Overcoming hypoxia-induced radioresistance of glioblastoma cells by hadrontherapy

Nolwenn Pasquet , Elodie A. Pérès , Jérôme Toutain , Myriam Bernaudin , Valable Samuel
ERRS 2021 - 46th Annual Meeting of the European Radiation Research Society, UNicaen; ERRS Society, Nov 2021, Caen, France
Conference papers hal-03616264v1

Brain Tumor Models & MRI Applications

Valable Samuel
10th Annual 'In vivo Preclinical Imaging and Drug Discovery Workshop, Dec 2021, Bombay, India
Conference papers hal-03561756v1

Investigating the interest of proton therapy to obtund radiation-induced lymphopenia in a context of brain tumour irradiation: a preclinical study

Julie Coupey , Jérôme Toutain , Erika Hue , C Hélaine , Jade Richard
“Adaptation of the tumour and its ecosystem to radiotherapies“ workshop (14th CGO), Sep 2021, Le Bono, France
Conference papers hal-03444560v1

Development and in vivo preclinical validation of [18F]FLUSONIM, a highly hydrophilic 18F-labelled 2-nitroimidazole derivative for high performance hypoxia PET imaging

C. Maingueneau , A.-E. Lafargue , F. Fillesoye , J. Toutain , S. Valable
4th Nuclear Technologies for Health Symposium, NTHS2020, Feb 2020, Nantes, France
Conference papers hal-02489356v1

Early brain metastases treatment using VCAM-1 targeted alpha-particle therapy

A Corroyer-Dulmont , S Valable , N Falzone , Am Frelin-Labalme , O Tietz
4th Nuclear Technologies for Health Symposium, NTHS2020, Feb 2020, Nantes, France
Conference papers hal-02488870v1

Measurement of radionuclide spatial and temporal distribution and dose calculation for in vitro assessments of 212Pb-αVCAM-1 targeted alpha therapy

A.M. Frelin-Labalme , T. Roger , N Falzone , B Quan Lee , Nr Sibson
4th Nuclear Technologies for Health Symposium, NTHS 2020, Feb 2020, Nantes, France
Conference papers hal-02488871v1

Relevance of multiparametric MRI to accurately detect radiation-induced brain injury in the rat

C. Brunaud , S. Valable , F.A. Dwiri , G. Ropars , J. Toutain
Journée de travail Cancéropôle Nord-Ouest, Axe 3 « Imagerie et adaptation thérapeutique » : Place de l'imagerie médicale dans la précision thérapeutique, Dec 2020, e-congrès, France
Conference papers hal-03167478v1

Presse numérique CNRS : "Nanocrystals to deliver oxygen to brain tumours"

Valable Samuel
Communiqué Presse CNRS lié à la parution du Biomaterials (Anfray et al. 2020), Aug 2020, Paris, France
Conference papers hal-03564172v1

ONCOModels/Cyceron facilities

Valable Samuel
ENLIGHT 2019, Jul 2019, Caen, France
Conference papers hal-02284844v1

Développement et validation préclinique in vivo du [18F]FLUSONIM pour l’imagerie TEP de l’hypoxie de haute performance

Clémence Maingueneau , Anne-Élodie Lafargue , Fabien Fillesoye , Jérôme Toutain , Samuel Valable
Journées scientifiques du Cancéropôle Nord-Ouest, Dec 2019, Lille, France
Conference papers hal-02414509v1

Evaluation des dommages cérébraux radio-induits par l’exposition à de faibles et fortes doses de rayonnements ionisants sur un modèle de rat adulte

Elodie Pérès , Jérôme Toutain , Carole Brunaud , François Kauffmann , Mikaël Naveau
12èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2019, Deauville, France
Conference papers hal-02266823v1

Etude multiparamétrique des effets de l'irradiation cérébrale chez le rat : des altérations tissulaires jusqu'aux déficits cognitifs

Gwenn Ropars , Rozenn Le Gal , Fatima-Azzahra Dwiri , Jérôme Toutain , Carole Brunaud
12èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2019, Deauville, France
Conference papers hal-02266824v1

Evaluation par IRM des dommages cérébraux induits par la radiothérapie dans un modèle de rat

Elodie Pérès , Jérôme Toutain , Carole Brunaud , Omar Touzani , Edwige Petit
3ème Congrès National d'Imagerie du Vivant (CNIV), Feb 2019, Paris, France
Conference papers hal-02266830v1

Spécificité de l'imagerie en Hadronthérapie

S. Valable
Congrès Annuel Axe 3 Cancéropôle Nord Ouest, Dec 2019, Lille, France
Conference papers hal-02429577v1

Impact of tumor reoxygenation by nanoparticles on tumors associated macrophages.

A Ferré , H Ozcelik , M.M. Leblond , C Anfray , C Hélaine
24ème édition des journées de l'école doctorale EdNBISE, Mar 2019, Caen, France
Conference papers hal-02266827v1

VCAM-1 targeted alpha-particle therapy for early brain metastases

Aurélien Corroyer-Dulmont , Samuel Valable , Nadia Falzone , Anne-Marie Frelin-Labalme , Ole Tietz
ICRR 2019, Aug 2019, Manchester, United Kingdom
Conference papers hal-02266822v1

Radionuclide spatial distribution mesurement and dose deposition for in vitro assessments of targeted alpha

A.M. Frelin-Labalme , T Roger , N Falzone , Lee B Quan , Nr Sibson
International Conference on Medical Physics and School, Jul 2019, Quy Nhon, Vietnam
Conference papers hal-02305030v1

64Cu-ATSM in glioblastoma and its relation to hypoxia

Valable Samuel
Journées Scientifiques de l'université de Nantes, Jun 2019, Nantes, France
Conference papers hal-02284853v1

VCAM-1 targeted alpha-particle therapy for early brain metastases

A Corroyer-Dulmont , S Valable , N Falzone , A.M. Frelin-Labalme , O Tietz
4ème Journée Normande de Recherche Biomédicale, JNRB 2019, Nov 2019, Caen, France
Conference papers hal-02402378v1

Hypoxia image-Guided Radiotherapy for the treatment of brain metastases from primary lung cancer, a preclinical study.

Aurélien Corroyer-Dulmont , Samuel Valable , Jérôme Toutain , Didier Divoux , Méziane Ibazizene
3ème Congrès National d'Imagerie du Vivant (CNIV), Feb 2019, Paris, France
Conference papers hal-02200579v1

Multimodal and multiscale imaging for glioblastoma : interest for prognostic and assessment of treatment efficacy

Valable Samuel
Novel microscopy imaging techniques for tissue analytics, Apr 2019, Vilnius, Lithuania
Conference papers hal-02284903v1

Nanosized zeolites as a theranostic tool to oxygenate and to image aggressive brain tumors with MRI

Samuel Valable
EMRS 2018 Spring Meeting 1st international Workshop on zeolites, Jun 2018, Strasbourg, France
Conference papers hal-02275005v1

Heparan sulfate mimetics are neuroprotective and neuroregenerative agents for ischemic stroke.

Y Khelif , J Toutain , Ms Quittet , S Chantepie , X Laffray
Bioregate Forum - European Regenrative Medicine, Dec 2018, Nantes, France
Conference papers hal-02267171v1

Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study

A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène
3ème Journée Normande de Recherche Biomédicale, JNRB 2018, Sep 2018, Rouen, France
Conference papers hal-02267175v1

Hypoxia imaging: interest of Image-Guided Radiotherapy for the treatment of brain metastases from lung cancer, a preclinical study

A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène
Workshop “Imaging and therapeutic targeting in cancerology: New advances and trends in preclinical and clinical studies”., Sep 2018, Le Bono, France
Conference papers hal-02267161v1

Prostate cancer heterogeneity: texture analysis of multiple MRI sequences for detection and selection of biopsy targets.

C Orczyk , A Villers , H Rusinek , V Le Pennec , C Bazille
2018 American Urological Association's Annual Meeting, May 2018, San Francisco, United States
Conference papers hal-02267164v1

L’Hadronthérapie : pourquoi, pour qui, comment ? Quelle place pour l’imagerie ?

Samuel Valable
3ème séminaire Scientifique du Réseau Normand d’Innovation Thérapeutique en Oncologie « OncoThera », Nov 2018, Caen, France
Conference papers hal-02274996v1

Observation of immunological responses to different types of beam

Samuel Valable
ENLIGHT 2018, Jun 2018, Londres, United Kingdom
Conference papers hal-02275001v1

A new theranostic strategy for brain tumors using zeolites nanocrystals

Samuel Valable
1st international Workshop on zeolites, May 2018, Gqingdao, China
Conference papers hal-02275010v1

FMISO-PET-derived brain oxygen tension maps: application to glioblastoma and less aggressive gliomas

A. Chakhoyan , Js. Guillamo , S. Collet , F. Kauffmann , N. Delcroix
Journée du Cancéropôle Nord-Ouest Axe 3 : "Imagerie Fonctionnelle et Radiothérapie”, Dec 2017, Caen, France
Conference papers hal-02268075v1

StO2-MRI sensitively images hypoxia in the brain: validation in both ischemic and tumoral situations

S Valable , J Toutain , A Corroyer-Dulmont , A Chakhoyan , D Divoux
2ème Congrès National d'Imagerie du Vivant CNIV 2017, Nov 2017, Paris, France
Conference papers hal-02268068v1

Implication de HAF dans la croissance des glioblastomes : caractérisation in vitro et in vivo

G Lambert , E.A. Pérès , K Bordji , D Divoux , J Toutain
10èmes journées scientifiques du Cancéropôle Nord-Ouest, May 2017, Deauville, France
Conference papers hal-02268085v1

Caractérisation par imagerie multimodale IRM et TEP des métastases cérébrales pour l’adaptation des traitements de radiothérapie

A Corroyer-Dulmont , S Valable , J Toutain , D Divoux , M Ibazizène
Journée du Cancéropôle Nord-Ouest Axe 3 : "Imagerie Fonctionnelle et Radiothérapie”, Dec 2017, Caen, France
Conference papers hal-02268079v1

Imagerie médicale et tumeurs : diagnostic,orientation thérapeutique et suivi de l’efficacité des traitements. Conférence

S Valable
Association Poursuivre, Nov 2017, Caen, France
Conference papers hal-02332010v1

Biomedical use of nanosized zeolites for aggressive brain tumors

Anfray C. , Goldyn K. , Komaty S. , Allioux C. , Zaarour M.
7th FEZA Conference “The ZEOLITES: Materials with Engineered Properties”, Jul 2017, Sofia, Bulgaria
Conference papers hal-02268071v1

Nanosized zeolites for biomedical applications

C. Anfray , Kamila Matysiak , Sarah Komaty , C. Allioux , K Bordji
7th FEZA Conference, Jul 2017, Sofia, Bulgaria
Conference papers hal-02067251v1

18F]Fludarabine-PET as a promising tool in differentiation between CNS lymphoma and glioblastoma: comparative analysis with [18F]FDG in human xenograft models

N. Hovhannisyan , S. Guillouet , M. Dhilly , M. Ibazizene , F. Fillesoye
Journée du Cancéropôle Nord-Ouest Axe 3 : "Imagerie Fonctionnelle et Radiothérapie”, Dec 2017, Caen, France
Conference papers hal-02268076v1

Nanosized zeolites do not induce adverse effect on eucaryotic cells

C. Anfray , Kamila Matysiak , Sarah Komaty , C. Allioux , K. Bordji
33rd GFZ, Mar 2017, Marne la Vallée, France
Conference papers hal-02067551v1

Nanosized zeolites do not induce adverse effect on eukaryotic cells

C. Anfray , K. Goldyn , S. Komaty , C. Allioux , K. Bordji
20ème Journées de l’Ecole doctorale Normande de Biologie Intégrative, Santé, Environnement (EdNBISE), Mar 2017, Le Havre, France
Conference papers hal-02268080v1