Sandrine Cojean

Maître de Conférences à Université Paris-Saclay (Orsay) Ingénieure en Recherche Hospitalière à CNR Paludisme (Hôpital Bichat Claude Bernard, Paris)
27
Documents

Compétences

Biologie cellulaire, biologie moléculaire, protozoaires, résistance médicamenteuse Leishmania, Plasmodium

Publications

Publications

Are hydrophilic deep eutectic solvents a potential vehicle for topical delivery of Amphotericin B against cutaneous leishmaniasis? An investigation of physicochemical properties, tolerability and antileishmanial efficacy

Cảnh Hưng Nguyễn , Catherine Cailleau , Natalie Fournier , Luc Augis , Françoise Mercier-Nomé et al.

International Journal of Pharmaceutics, 2026, 689, pp.126439. ⟨10.1016/j.ijpharm.2025.126439⟩

Article dans une revue hal-05397306v1
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Re-sensitization of antimony-resistant Leishmania by highly potent SbV-porphyrin through the involvement of ERG6-coding gene

Ellen Gonçalves De Oliveira , Juliane Sousa Lanza , Sandrine Cojean , Paulo Otávio L. Moreira , Luiza Guimarães Tunes et al.

Biomedicine and Pharmacotherapy, 2025, 187, pp.118059. ⟨10.1016/j.biopha.2025.118059⟩

Article dans une revue hal-05445980v1
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Resistance to Antileishmanial Drug Candidates: A Flowchart for an Early Phenotypic Evaluation of Risk

Nalia Mekarnia , Sandrine Cojean , Philippe Loiseau

Drugs and Drug Candidates, 2025, 4 (3), pp.38. ⟨10.3390/ddc4030038⟩

Article dans une revue hal-05235475v1

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

Lhana Tisseur , Cédric Logé , Sandrine Cojean , Khadidiatou Gassama , Lilian Karcher et al.

RSC Medicinal Chemistry, 2025, 16, pp.3746-3763. ⟨10.1039/d5md00257e⟩

Article dans une revue hal-05173262v1

Chemical analysis by molecular networking methods on extracts of Saba senegalensis (A.DC.) Pichon (Apocynaceae) and its anthelmintic activity on Caenorhabditis elegans

Mohamed Belemlilga , Hazrina Hazni , Aristide Traore , Indira Dennemont , Sébastien Pomel et al.

Clinical Traditional Medicine and Pharmacology, 2025, 6 (1), pp.200195. ⟨10.1016/j.ctmp.2025.200195⟩

Article dans une revue hal-05149228v1
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Assessment of ex vivo antimalarial drug efficacy in African Plasmodium falciparum parasite isolates, 2016–2023: a genotype–phenotype association study

Jason Rosado , Abebe Fola , Sandrine Cojean , Véronique Sarrasin , Romain Coppée et al.

EBioMedicine, 2025, 118 (1), pp.105835. ⟨10.1016/j.ebiom.2025.105835⟩

Article dans une revue hal-05169453v2

Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

Lhana Tisseur , Sandrine Cojean , Khadidiatou Gassama , Cédric Logé , Fabrice Pagniez et al.

ChemMedChem, 2025, 20 (6), pp.e202400862. ⟨10.1002/cmdc.202400862⟩

Article dans une revue hal-05181232v1
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Synthesis and in vitro/in silico evaluation of the antimalarial activity of potential amino-quinoline derivatives

Moussa Touré , Abdoulaye Gassama , Oumar Sambou , Christian Cavé , Sandrine Cojean

European Journal of Medicinal Chemistry Reports, 2025, 13, pp.100241. ⟨10.1016/j.ejmcr.2024.100241⟩

Article dans une revue hal-05445961v1
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Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms

Gulsah Bayraktar , Pascal Marchand , Euzébio Guimarães Barbosa , Marilia Cecilia da Silva , Karen Cacilda Weber et al.

European Journal of Medicinal Chemistry Reports, 2024, 12, pp.100228. ⟨10.1016/j.ejmcr.2024.100228⟩

Article dans une revue hal-05088062v1
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The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities

Imen Abid , Wassim Moslah , Sandrine Cojean , Nicolas Imbert , Philippe M Loiseau et al.

Molecules, 2024, 29 (8), pp.1819. ⟨10.3390/molecules29081819⟩

Article dans une revue hal-04550832v1
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Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones

Thibault Gendron , Don Antoine Lanfranchi , Nicole I Wenzel , Hripsimée Kessedjian , Beate Jannack et al.

Molecules, 2024, 29 (7), pp.1620. ⟨10.3390/molecules29071620⟩

Article dans une revue hal-04583951v1
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Effect of Phlebotomus papatasi on the fitness, infectivity and antimony-resistance phenotype of antimony-resistant Leishmania major Mon-25

Nalia Mekarnia , Kamal-Eddine Benallal , Jovana Sádlová , Barbora Vojtková , Aurélie Mauras et al.

International journal for parasitology. Drugs and drug resistance, 2024, 25, pp.100554. ⟨10.1016/j.ijpddr.2024.100554⟩

Article dans une revue hal-04632483v1

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani

Lília Cabral , Sébastien Pomel , Sandrine Cojean , Patrícia Amado , Philippe Loiseau et al.

Molecules, 2020, 25 (3), pp.465. ⟨10.3390/molecules25030465⟩

Article dans une revue hal-05149167v1

Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru)

Pedro Vásquez-Ocmín , Sandrine Cojean , Elsa Rengifo , Soulaf Suyyagh-Albouz , Carlos Amasifuen Guerra et al.

Journal of Ethnopharmacology, 2018, 210, pp.372-385. ⟨10.1016/j.jep.2017.08.039⟩

Article dans une revue istex hal-05149102v1

New Water-Soluble Polymeric Prodrugs of 2-n-propylquinoline: Synthesis and Evaluation of In Vitro and In Vivo Activities Against Leishmania donovani

Vasanthan Ravichandran , Nalia Mekarnia , Sébastien Pomel , Sandrine Cojean , Laurent Ferrié et al.

Regenerative Engineering and Translational Medicine, 2018, 4 (1), pp.11-20. ⟨10.1007/s40883-018-0045-3⟩

Article dans une revue hal-05149115v1

Antiplasmodial Securinega alkaloids from Phyllanthus fraternus: Discovery of natural (+)-allonorsecurinine

Gustav Komlaga , Grégory Genta-Jouve , Sandrine Cojean , Rita Dickson , Merlin L.K. Mensah et al.

Tetrahedron Letters, 2017, 58 (38), pp.3754-3756. ⟨10.1016/j.tetlet.2017.08.045⟩

Article dans une revue istex hal-05521917v1

Antiplasmodial activity of selected medicinal plants used to treat malaria in Ghana

Gustav Komlaga , Sandrine Cojean , Rita Dickson , Mehdi Beniddir , Soulaf Suyyagh-Albouz et al.

Parasitology Research, 2016, 115 (8), pp.3185-3195. ⟨10.1007/s00436-016-5080-8⟩

Article dans une revue hal-05521857v1

Targeting sterol metabolism for the development of antileishmanials

Sébastien Pomel , Sandrine Cojean , Philippe Loiseau

Trends in Parasitology, 2015, 31 (1), pp.5-7. ⟨10.1016/j.pt.2014.11.007⟩

Article dans une revue istex hal-05148982v1

In vitro and in vivo antileishmanial properties of a 2-n-propylquinoline hydroxypropyl β-cyclodextrin formulation and pharmacokinetics via intravenous route

Kaluvu Balaraman , Nashira Campos Vieira , Fathi Moussa , Joël Vacus , Sandrine Cojean et al.

Biomedicine and Pharmacotherapy, 2015, 76, pp.127-133. ⟨10.1016/j.biopha.2015.10.028⟩

Article dans une revue istex hal-05149031v1

The Antimalarial Potential of Three Ghanaian Medicinal Plants

Gustav Komlaga , Sandrine Cojean , Mehdi A Beniddir

Herbal Medicine: Open Access, 2015, 1 (1), ⟨10.21767/2472-0151.10004⟩

Article dans une revue hal-05521840v1

VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis

Galina Lepesheva , Tatiana Hargrove , Girish Rachakonda , Zdzislaw Wawrzak , Sébastien Pomel et al.

Journal of Infectious Diseases, 2015, 212 (9), pp.1439-1448. ⟨10.1093/infdis/jiv228⟩

Article dans une revue hal-05149012v1

Synthesis and antiprotozoal activity of original porphyrin precursors and derivatives

Zahra Abada , Sandrine Cojean , Sébastien Pomel , Laurent Ferrié , Bernardin Akagah et al.

European Journal of Medicinal Chemistry, 2013, 67 (2), pp.158-165. ⟨10.1016/j.ejmech.2013.06.002⟩

Article dans une revue hal-05148876v1