Sandrine Cojean

Maître de Conférences à Université Paris-Saclay (Orsay) Ingénieure en Recherche Hospitalière à CNR Paludisme (Hôpital Bichat Claude Bernard, Paris)
22
Documents

Présentation


Compétences

Biologie cellulaire, biologie moléculaire, protozoaires, résistance médicamenteuse Leishmania, Plasmodium

Publications

Publications

Pharmacophore-guided optimization of the hit compound CTN1122 in the design of promising imidazo[1,2- a ]pyrazine derivatives targeting the casein kinase 1 for antileishmanial therapy

Lhana Tisseur , Cédric Logé , Sandrine Cojean , Khadidiatou Gassama , Lilian Karcher et al.
RSC Medicinal Chemistry, In press, ⟨10.1039/d5md00257e⟩
Article dans une revue hal-05173262 v1

Re-sensitization of antimony-resistant Leishmania by highly potent SbV-porphyrin through the involvement of ERG6-coding gene

Ellen Gonçalves De Oliveira , Juliane Sousa Lanza , Sandrine Cojean , Paulo Otávio L. Moreira , Luiza Guimarães Tunes et al.
Biomedicine and Pharmacotherapy, 2025, 187, pp.118059. ⟨10.1016/j.biopha.2025.118059⟩
Article dans une revue hal-05149237 v1

Chemical analysis by molecular networking methods on extracts of Saba senegalensis (A.DC.) Pichon (Apocynaceae) and its anthelmintic activity on Caenorhabditis elegans

Mohamed Belemlilga , Hazrina Hazni , Aristide Traore , Indira Dennemont , Sébastien Pomel et al.
Clinical Traditional Medicine and Pharmacology, 2025, 6 (1), pp.200195. ⟨10.1016/j.ctmp.2025.200195⟩
Article dans une revue hal-05149228 v1
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Assessment of ex vivo antimalarial drug efficacy in African Plasmodium falciparum parasite isolates, 2016–2023: a genotype–phenotype association study

Jason Rosado , Abebe Fola , Sandrine Cojean , Véronique Sarrasin , Romain Coppée et al.
EBioMedicine, 2025, 118 (1), pp.105835. ⟨10.1016/j.ebiom.2025.105835⟩
Article dans une revue hal-05169453 v1

Investigating the C2 Modulation of the Imidazo[1,2‐ a ]pyrazine‐Based Hit Compound CTN1122: Synthesis, in vitro Antileishmanial Activity, Cytotoxicity and Casein Kinase 1 Inhibition

Lhana Tisseur , Sandrine Cojean , Khadidiatou Gassama , Cédric Logé , Fabrice Pagniez et al.
ChemMedChem, 2025, 20 (6), pp.e202400862. ⟨10.1002/cmdc.202400862⟩
Article dans une revue hal-05181232 v1

Resistance to Antileishmanial Drug Candidates: A Flowchart for an Early Phenotypic Evaluation of Risk

Nalia Mekarnia , Sandrine Cojean , Philippe Loiseau
Drugs and Drug Candidates, 2025, 4 (3), pp.38. ⟨10.3390/ddc4030038⟩
Article dans une revue hal-05235475 v1
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The Synthesis of 2′-Hydroxychalcones under Ball Mill Conditions and Their Biological Activities

Imen Abid , Wassim Moslah , Sandrine Cojean , Nicolas Imbert , Philippe M Loiseau et al.
Molecules, 2024, 29 (8), pp.1819. ⟨10.3390/molecules29081819⟩
Article dans une revue hal-04550832 v1
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Biological properties and in silico studies of thiazolopyrimidine derivatives active against visceral and cutaneous Leishmania spp. amastigote forms

Gulsah Bayraktar , Pascal Marchand , Euzébio Guimarães Barbosa , Marilia Cecilia da Silva , Karen Cacilda Weber et al.
European Journal of Medicinal Chemistry Reports, 2024, 12, pp.100228. ⟨10.1016/j.ejmcr.2024.100228⟩
Article dans une revue hal-05088062 v1
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Chemoselective Synthesis and Anti-Kinetoplastidal Properties of 2,6-Diaryl-4H-tetrahydro-thiopyran-4-one S-Oxides: Their Interplay in a Cascade of Redox Reactions from Diarylideneacetones

Thibault Gendron , Don Antoine Lanfranchi , Nicole I Wenzel , Hripsimée Kessedjian , Beate Jannack et al.
Molecules, 2024, 29 (7), pp.1620. ⟨10.3390/molecules29071620⟩
Article dans une revue hal-04583951 v1
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Effect of Phlebotomus papatasi on the fitness, infectivity and antimony-resistance phenotype of antimony-resistant Leishmania major Mon-25

Nalia Mekarnia , Kamal-Eddine Benallal , Jovana Sádlová , Barbora Vojtková , Aurélie Mauras et al.
International journal for parasitology. Drugs and drug resistance, 2024, 25, pp.100554. ⟨10.1016/j.ijpddr.2024.100554⟩
Article dans une revue hal-04632483 v1

Synthesis and Antileishmanial Activity of 1,2,4,5-Tetraoxanes against Leishmania donovani

Lília Cabral , Sébastien Pomel , Sandrine Cojean , Patrícia Amado , Philippe Loiseau et al.
Molecules, 2020, 25 (3), pp.465. ⟨10.3390/molecules25030465⟩
Article dans une revue hal-05149167 v1

Antiprotozoal activity of medicinal plants used by Iquitos-Nauta road communities in Loreto (Peru)

Pedro Vásquez-Ocmín , Sandrine Cojean , Elsa Rengifo , Soulaf Suyyagh-Albouz , Carlos Amasifuen Guerra et al.
Journal of Ethnopharmacology, 2018, 210, pp.372-385. ⟨10.1016/j.jep.2017.08.039⟩
Article dans une revue hal-05149102 v1

New Water-Soluble Polymeric Prodrugs of 2-n-propylquinoline: Synthesis and Evaluation of In Vitro and In Vivo Activities Against Leishmania donovani

Vasanthan Ravichandran , Nalia Mekarnia , Sébastien Pomel , Sandrine Cojean , Laurent Ferrié et al.
Regenerative Engineering and Translational Medicine, 2018, 4 (1), pp.11-20. ⟨10.1007/s40883-018-0045-3⟩
Article dans une revue hal-05149115 v1

In vitro and in vivo antileishmanial properties of a 2-n-propylquinoline hydroxypropyl β-cyclodextrin formulation and pharmacokinetics via intravenous route

Kaluvu Balaraman , Nashira Campos Vieira , Fathi Moussa , Joël Vacus , Sandrine Cojean et al.
Biomedicine and Pharmacotherapy, 2015, 76, pp.127-133. ⟨10.1016/j.biopha.2015.10.028⟩
Article dans une revue hal-05149031 v1

Targeting sterol metabolism for the development of antileishmanials

Sébastien Pomel , Sandrine Cojean , Philippe Loiseau
Trends in Parasitology, 2015, 31 (1), pp.5-7. ⟨10.1016/j.pt.2014.11.007⟩
Article dans une revue hal-05148982 v1

VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis

Galina Lepesheva , Tatiana Hargrove , Girish Rachakonda , Zdzislaw Wawrzak , Sébastien Pomel et al.
Journal of Infectious Diseases, 2015, 212 (9), pp.1439-1448. ⟨10.1093/infdis/jiv228⟩
Article dans une revue hal-05149012 v1

Synthesis and antiprotozoal activity of original porphyrin precursors and derivatives

Zahra Abada , Sandrine Cojean , Sébastien Pomel , Laurent Ferrié , Bernardin Akagah et al.
European Journal of Medicinal Chemistry, 2013, 67 (2), pp.158-165. ⟨10.1016/j.ejmech.2013.06.002⟩
Article dans une revue hal-05148876 v1