Sébastien ARTHAUD

Ingénieur de Recherche à l'Université Claude Bernard Lyon1
56
Documents

Publications

Publications

Deposit thumbnail

ALTERATIONS DU SOMMEIL AU COURS DE LA VIE CHEZ DES SOURIS MODELISANT L'ACCUMULATION HUMAINE DE NEUROMELANINE DANS LES NEURONES CATECHOLAMINERGIQUES

Sébastien Arthaud , Jean-Christophe Comte , Jiong Liu , Núria Peñuelas , Ariadna Laguna et al.

Le congrès du Sommeil 2025, SFRMS, Nov 2025, Strasbourg, France

Communication dans un congrès hal-05347198v1

Modelling human REM sleep Behavior Disorder (RBD), a prodromal marker of synucleinopathies, using genetic tools in wild-type mice

Blandine Duval , Sébastien Arthaud , Justin Malcey , Amarine Chancel , Luppi Pierre-Hervé et al.

Neurofrance 2025, Société Française des Neurosciences (SDN), May 2025, Montpellier, France

Communication dans un congrès hal-05119309v1
Deposit thumbnail

Réseaux neuronaux de l'atonie musculaire : nouvelles données dans la compréhension fonctionnelle du trouble du comportement en sommeil paradoxal

Blandine Duval , Sébastien Arthaud , Justin Malcey , Amarine Chancel , Pierre-Hervé Luppi et al.

Le congrès du Sommeil 2025, SFRMS, Nov 2025, Strasbourg, France

Communication dans un congrès hal-05347171v1
Deposit thumbnail

Modeling EEG data using deep learning for automatic sleep stage classification in mice

L. Rose , A.N. Zahid , L. Piilgaard , C.G. Hviid , C.E. Jensen et al.

17th World Sleep Congress, Oct 2023, Rio de Janeiro, Brazil. pp.S411-S412, ⟨10.1016/j.sleep.2023.11.1104⟩

Communication dans un congrès hal-04788391v1
Deposit thumbnail

Moderate RBD symptoms in narcoleptic versus IRBD mice.

Maxime Grenot , Alexis Roman , Sébastien Arthaud , Paul-Antoine Libourel , Christelle Peyron

17th World Sleep Congress, Oct 2023, Rio de Janeiro, Brazil. pp.S200

Communication dans un congrès hal-04788236v1

Evolution of the sleep-waking cycle in transgenic mice with an age-dependent accumulation of neuromelanin in catecholaminergic neurons, a new humanized model of Parkinson's Disease

Sébastien Arthaud , Jiong Liu , Nuria Peñuelas , Ariadana Laguna , Miquel Vila et al.

Forum Federation of European Neuroscience Societies (FENS), Jul 2022, PARIS, France

Communication dans un congrès hal-03748322v1

Hypothalamic regulation of REM sleep

Luppi Pierre-Hervé , Olivier Clément , Emilie Sapin , Paul-Antoine Libourel , Sébastien Arthaud et al.

21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. pp.2-3

Communication dans un congrès hal-02345917v1

Gliotransmission et sensibilité centrale au glucose : rôle des endozépines

Fabrice Morin , Damien Lanfray , Sébastien Arthaud , Johana Ouellet , Vincent Compère et al.

39ème colloque de la Société de Neuroendocrinologie, Sep 2013, Fès, Maroc

Communication dans un congrès hal-02454954v1
Deposit thumbnail

Probability estimation of narcolepsy type 1 in DTA mice using unlabeled EEG and EMG data

Laura Rose , Alexander Neergaard Zahid , Louise Piilgaard , Christine Egebjerg , Frederikke Lynge Sørensen et al.

SLEEP Advances, 2025, 6 (2), zpaf025. ⟨10.1093/sleepadvances/zpaf025⟩

Article dans une revue hal-05120846v1
Deposit thumbnail

Early-onset sleep alterations found in patients with amyotrophic lateral sclerosis are ameliorated by orexin antagonist in mouse models

Simon J Guillot , Christina Lang , Marie Simonot , Daniel Beckett , Dorothée Lulé et al.

Science Translational Medicine, 2025, 17 (783), pp.eadm7580. ⟨10.1126/scitranslmed.adm7580⟩

Article dans une revue inserm-05509033v1

Sleep-dependent infraslow rhythms are evolutionarily conserved across reptiles and mammals

Antoine Bergel , Julien Schmidt , Baptiste Barrillot , Sébastien Arthaud , Laetitia Averty et al.

Nature Neuroscience, 2025, ⟨10.1038/s41593-025-02159-y⟩

Article dans une revue hal-05495102v1
Deposit thumbnail

Bridging the gap between lab and field sleep studies: a proof-of-concept for studying wild rats in semi-captive environments

Paul-Antoine Libourel , Sébastien Arthaud , Antoine Bergel , Fabrice Brescia , Azzedine Dib et al.

SLEEP Advances, 2025, 6 (2), zpaf036 [12 p.]. ⟨10.1093/sleepadvances/zpaf036⟩

Article dans une revue hal-05519164v1
Deposit thumbnail

Modelling human neuronal catecholaminergic pigmentation in rodents recapitulates age-related neurodegenerative deficits

Ariadna Laguna , Núria Peñuelas , Marta Gonzalez-Sepulveda , Alba Nicolau , Sébastien Arthaud et al.

Nature Communications, 2024, 15 (1), pp.8819. ⟨10.1038/s41467-024-53168-7⟩

Article dans une revue hal-04767989v1
Deposit thumbnail

Major alteration of motor control during rapid eye movements sleep in mice models of sleep disorders

Maxime Grenot , Alexis Roman , Manon Villalba , Anne-Laure Morel , Patrice Fort et al. Article dans une revue hal-04768098v1
Deposit thumbnail

Two polygenic mouse models of major depressive disorders identify TMEM161B as a potential biomarker of disease in humans

Malika El Yacoubi , Claire Altersitz , Violaine Latapie , Elari Rizkallah , Sébastien Arthaud et al.

Neuropsychopharmacology, 2024, 49, pp.1129-1139. ⟨10.1038/s41386-024-01811-8⟩

Article dans une revue inserm-04444848v1

Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy

Raphaël Bernard-Valnet , David Frieser , Xuan-Hung Nguyen , Leila Khajavi , Clémence Quériault et al.

Brain - A Journal of Neurology , 2022, 145 (6), pp.2018-2030. ⟨10.1093/brain/awab455⟩

Article dans une revue hal-03669984v1
Deposit thumbnail

Effects of sex and estrous cycle on sleep and cataplexy in narcoleptic mice

Sébastien Arthaud , Manon Villalba , Camille Blondet , Anne-Laure Morel , Christelle Peyron

Sleep, 2022, 45 (7), ⟨10.1093/sleep/zsac089⟩

Article dans une revue hal-03748304v1
Deposit thumbnail

Granule cells in the infrapyramidal blade of the dentate gyrus are activated during paradoxical (REM) sleep hypersomnia but not during wakefulness: a study using TRAP mice

Risa Yamazaki , Dianru Wang , Anna de Laet , Renato Maciel , Claudio Agnorelli et al.

Sleep, 2021, 44 (12), pp.zsab173. ⟨10.1093/sleep/zsab173⟩

Article dans une revue hal-03400920v1
Deposit thumbnail

Is REM sleep a paradoxical state?: Different neurons are activated in the cingulate cortices and the claustrum during wakefulness and paradoxical sleep hypersomnia

Renato Maciel , Risa Yamazaki , Dianru Wang , Anna de Laet , Sébastien Cabrera et al.

Biochemical Pharmacology, 2021, 191, pp.114514. ⟨10.1016/j.bcp.2021.114514⟩

Article dans une revue hal-03285342v1

Insights into paradoxical (REM) sleep homeostatic regulation in mice using an innovative automated sleep deprivation method

Sébastien Arthaud , Paul-Antoine Libourel , Pierre-Hervé Luppi , Christelle Peyron

Sleep, 2020, 43 (7), ⟨10.1093/sleep/zsaa003⟩

Article dans une revue hal-03104247v1
Deposit thumbnail

Targeted recombination in active populations as a new mice genetic model to study sleep‐active neuronal populations: Demonstration that Lhx6+ neurons in the ventral zona incerta are activated during paradoxical sleep hypersomnia

Hyun‐sook Lee , Risa Yamazaki , Dianru Wang , Sébastien Arthaud , Patrice Fort et al.

Journal of Sleep Research, 2020, ⟨10.1111/jsr.12976⟩

Article dans une revue hal-02996227v1
Deposit thumbnail

Defining and measuring paradoxical (REM) sleep in animal models of sleep disorders

Christelle Peyron , Sébastien Arthaud , Manon Villalba , Patrice Fort

Current Opinion in Physiology, 2020, 15, pp.203-209. ⟨10.1016/j.cophys.2020.03.008⟩

Article dans une revue hal-02996296v1

INTRAMUSCULAR ADMINISTRATION OF KETAMINE-MEDETOMIDINE ASSURES STABLE ANAESTHESIA NEEDED FOR LONG-TERM SURGERY IN THE ARGENTINE TEGU SALVATOR MERIANAE

Baptiste Barrillot , Johanna Roux , Sébastien Arthaud , Laëtitia Averty , Angeline Clair et al.

Journal of Zoo and Wildlife Medicine, 2018, 49 (2), pp.291-296. ⟨10.1638/2017-0089.1⟩

Article dans une revue hal-02105781v1
Deposit thumbnail

Ventromedial medulla inhibitory neuron inactivation induces REM sleep without atonia and REM sleep behavior disorder

Sara Valencia Garcia , Frédéric Brischoux , Olivier Clément , Paul-Antoine Libourel , Sébastien Arthaud et al.

Nature Communications, 2018, 9 (1), ⟨10.1038/s41467-017-02761-0⟩

Article dans une revue hal-02104823v1
Deposit thumbnail

ONEIROS, a new miniature standalone device for recording sleep electrophysiology, physiology, temperatures and behavior in the lab and field

Bertrand Massot , Sébastien Arthaud , Baptiste Barrillot , Johanna Roux , Gianina Ungurean et al.

Journal of Neuroscience Methods, 2018, ⟨10.1016/j.jneumeth.2018.08.030⟩

Article dans une revue hal-01890562v1

The inappropriate occurrence of rapid eye movement sleep in narcolepsy is not due to a defect in homeostatic regulation of rapid eye movement sleep

Alexis Roman , Soraya Meftah , Sébastien Arthaud , Pierre-Hervé Luppi , C. Peyron

Sleep, 2018, 41 (6), pp.zsy046. ⟨10.1093/sleep/zsy046⟩

Article dans une revue hal-02368936v1
Deposit thumbnail

Partial homologies between sleep states in lizards, mammals, and birds suggest a complex evolution of sleep states in amniotes

Paul-Antoine Libourel , Baptiste Barrillot , Sébastien Arthaud , Bertrand Massot , Anne-Laure Morel et al.

PLoS Biology, 2018, 16 (10), pp.e2005982. ⟨10.1371/journal.pbio.2005982⟩

Article dans une revue hal-02105758v1

REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP

Pascal Ravassard , Al Mahdy Hamieh , Mickaël Antoine Joseph , Nicolas Fraize , Paul-Antoine Libourel et al.

Cerebral Cortex, 2016, 26 (4), pp.1488-1500. ⟨10.1093/cercor/bhu310⟩

Article dans une revue hal-04773763v1

CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice

Raphaël Bernard-Valnet , Lidia Yshii , Clémence Quériault , Xuan-Hung Nguyen , Sébastien Arthaud et al.

Proceedings of the National Academy of Sciences of the United States of America, 2016, 113 (39), pp.10956 - 10961. ⟨10.1073/pnas.1603325113⟩

Article dans une revue hal-01824562v1

REM Sleep-Dependent Bidirectional Regulation of Hippocampal-Based Emotional Memory and LTP

Pascal Ravassard , Al Mahdy Hamieh , Mickaël Antoine Joseph , Nicolas Fraize , Paul-Antoine Libourel et al.

Cerebral Cortex, 2016, 26 (4), pp.1488-1500. ⟨10.1093/cercor/bhu310⟩

Article dans une revue hal-03398976v1

Sleep architecture and homeostasis in mice with partial ablation of melanin-concentrating hormone neurons

Christophe Varin , Sébastien Arthaud , Denise Salvert , Nadine Gay , Paul-Antoine Libourel et al.

Behavioural Brain Research, 2016, 298, pp.100-110. ⟨10.1016/j.bbr.2015.10.051⟩

Article dans une revue hal-02336931v1

Paradoxical (REM) sleep deprivation in mice using the small-platforms-over-water method: polysomnographic analyses and melanin-concentrating hormone and hypocretin/orexin neuronal activation before, during and after deprivation

Sébastien Arthaud , Christophe Varin , Nadine Gay , Paul-Antoine Libourel , Frédéric Chauveau et al.

Journal of Sleep Research, 2015, 24 (3), pp.309-319. ⟨10.1111/jsr.12269⟩

Article dans une revue hal-02336938v1
Deposit thumbnail

Glucose Induces Slow-Wave Sleep by Exciting the Sleep-Promoting Neurons in the Ventrolateral Preoptic Nucleus: A New Link between Sleep and Metabolism

Christophe Varin , Armelle Rancillac , Hélène Geoffroy , Sébastien Arthaud , Patrice Fort et al.

Journal of Neuroscience, 2015, 35 (27), pp.9900-9911. ⟨10.1523/JNEUROSCI.0609-15.2015⟩

Article dans une revue inserm-02121070v1
Deposit thumbnail

Biochemical Characterization of a Caspase-3 Far-red Fluorescent Probe for Non-invasive Optical Imaging of Neuronal Apoptosis

Valérie Jolivel , Sébastien Arthaud , Béatrice Botia , Christophe Portal , Bruno Delest et al.

Journal of Molecular Neuroscience, 2014, 54 (3), pp.451-462. ⟨10.1007/s12031-014-0325-4⟩

Article dans une revue hal-01196843v1

Concordant localization of functional urotensin II and urotensin II-related peptide binding sites in the rat brain: Atypical occurrence close to the fourth ventricle

Christine Bucharles , Patrice Bizet , Sébastien Arthaud , Arnaud Arabo , Jérôme Leprince et al.

Journal of Comparative Neurology, 2014, 522 (11), pp.2634-2649. ⟨10.1002/cne.23553⟩

Article dans une revue istex hal-01958600v1
Deposit thumbnail

The Inhibition of the Dorsal Paragigantocellular Reticular Nucleus Induces Waking and the Activation of All Adrenergic and Noradrenergic Neurons: A Combined Pharmacological and Functional Neuroanatomical Study

Olivier Clément , Sara Valencia Garcia , Paul-Antoine Libourel , Sébastien Arthaud , Patrice Fort et al.

PLoS ONE, 2014, 9 (5), pp.e96851. ⟨10.1371/journal.pone.0096851⟩

Article dans une revue hal-02337032v1

Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

Damien Lanfray , Sébastien Arthaud , Johanne Ouellet , Vincent Compère , Jean-Luc Do Rego et al.

Diabetes, 2013, 62 (3), pp.801 - 810. ⟨10.2337/db11-0785⟩

Article dans une revue hal-01939215v1
Deposit thumbnail

Gliotransmission and Brain Glucose Sensing: Critical Role of Endozepines

Damien Lanfray , Sébastien Arthaud , Johanne Ouellet , Vincent Compère , Jean-Luc Do Rego et al.

Diabetes, 2013, 62 (3), pp.801-810. ⟨10.2337/db11-0785⟩

Article dans une revue hal-01962799v1

The Lateral Hypothalamic Area Controls Paradoxical (REM) Sleep by Means of Descending Projections to Brainstem GABAergic Neurons

Olivier Clément , Emilie Sapin , Paul-Antoine Libourel , Sébastien Arthaud , Frédéric Brischoux et al.

Journal of Neuroscience, 2012, 32 (47), pp.16763-16774. ⟨10.1523/JNEUROSCI.1885-12.2012⟩

Article dans une revue hal-02339533v1
Deposit thumbnail

The PACAP-regulated gene selenoprotein T is highly induced in nervous, endocrine, and metabolic tissues during ontogenetic and regenerative processes.

Yannick Tanguy , Anthony Falluel-Morel , Sébastien Arthaud , Loubna Boukhzar , Destiny-Love Manecka et al.

Endocrinology, 2011, 152 (11), pp.4322-35. ⟨10.1210/en.2011-1246⟩

Article dans une revue hal-00682913v1

Balanced effect of PACAP and FasL on granule cell death during cerebellar development: a morphological, functional and behavioural characterization.

Aurélie Allais , Delphine Burel , Vincent Roy , Sébastien Arthaud , Ludovic Galas et al.

Journal of Neurochemistry, 2010, 113 (2), pp.329-40. ⟨10.1111/j.1471-4159.2009.06555.x⟩

Article dans une revue pasteur-00819614v1
Deposit thumbnail

Functional remodeling of gap junction-mediated electrical communication between adrenal chromaffin cells in stressed rats.

Claude Colomer , Luis A. Olivos Ore , Nathalie Coutry , Marie-Noëlle Mathieu , Sébastien Arthaud et al.

Journal of Neuroscience, 2008, 28 (26), pp.6616-26. ⟨10.1523/JNEUROSCI.5597-07.2008⟩

Article dans une revue inserm-00281272v1
Deposit thumbnail

LIFESPAN SLEEP ALTERATION IN MICE MODELLING THE HUMAN NEUROMELANIN ACCUMULATION IN CATECHOLAMINERGIC NEURONS

Sébastien Arthaud , Jean-Christophe Comte , Jiong Liu , Núria Peñuelas , Anna Lagunas et al.

Neurofrance 2025, May 2025, Montpellier, France. 2025

Poster de conférence hal-05119338v1

Nouveau modèle expérimental de trouble du comportement en sommeil paradoxal (TCSP) chez la souris sauvage

Blandine Duval , Sebastien Arthaud , Justin Malcey , Amarine Chancel , Pierre-Hervé Luppi et al.

Le congrès du Sommeil 2024, Nov 2024, Lille, France. 22 (1), pp.85, 2025, ⟨10.1016/j.msom.2025.01.137⟩

Poster de conférence hal-05119375v1

DEVELOPMENT OF A PRECLINICAL MODEL OF REM SLEEP BEHAVIOR DISORDER (RBD), A PRODROMAL PARASOMNIA OF PARKINSON’S DISEASE, IN M83 TRANSGENIC MICE

Sébastien Arthaud , Maxime Grenot , Latifa Lakhdar , Thierry Baron , Patrice Fort

Neurofrance 2023, May 2023, LYON, France

Poster de conférence hal-04178071v1

EVOLUTION WITH AGING OF SLEEP MICROARCHITECTURE IN MICE ACCUMULATING NEUROMELANIN IN CATECHOLAMINERGIC NEURONS, A NEW HUMANIZED PARKINSON’S DISEASE MODEL

Patrice Fort , Romain Bouet , Maxime Grenot , Jiong Liu , Nuria Peñuelas et al.

NeuroFrance 2023, May 2023, Lyon, France

Poster de conférence hal-04178056v1

Evolution of the sleep-waking cycle in transgenic mice with an age-dependent accumulation of neuromelanin in catecholaminergic neurons, a new humanized model of Parkinson’s Disease

Sébastien Arthaud , Jiong Liu , Nuria Peñuelas , Ariadana Laguna , Miquel Vila et al.

FENS Forum, Jul 2022, PARIS, France

Poster de conférence hal-04176874v1

Modulation of hypothalamic MCH-expressing neurons by pharmacogenetic tools strongly alters the sleep-waking cycle in mice

Christophe Varin , Sébastien Arthaud , Yohan Cherasse , Michael Lazarus , Thierry Gallopin et al.

22nd Congress of the European-Sleep-Research-Society, Sep 2014, Tallinn, Estonia. Journal of sleep Research, 23 (P808), pp.254, 2014

Poster de conférence hal-02345870v1

Efficient paradoxical (REM) sleep homeostatic regulation in mice: reports on sleep architecture and neuronal activation

Sébastien Arthaud , Christophe Varin , Paul-Antoine Libourel , Patrice Fort , Pierre-Hervé Luppi et al.

22nd Congress of the European-Sleep-Research-Society, Sep 2014, Tallinn, Estonia. Journal of leep Research, 23 (P854), pp.270-71, 2014

Poster de conférence hal-02345904v1

Unsupervised paradoxical sleep deprivation using real-time sleep scoring in rats: a new alternative to the 'flower pot' technique

Paul-Antoine Libourel , Sonia Jego , Patrice Fort , Frédéric Brischoux , Jérémy Nigri et al.

21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. 21, pp.326-327, 2012

Poster de conférence hal-02347128v1

Evidence that the lateral hypothalamic area controls paradoxical (REM) sleep by means of descending projections to brainstem GABAergic neurons

Clément Olivier , Emilie Sapin , Paul-Antoine Libourel , Sébastien Arthaud , Patrice Fort et al.

21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. Journal of Sleep Research, 21, pp.193, 2012

Poster de conférence hal-02347007v1

Selective paradoxical sleep deprivation in mice using a new unsupervised automatic method

Sébastien Arthaud , Paul-Antoine Libourel , Patrice Fort , Damien Gervasoni , Pierre-Hervé Luppi

21st Congress of the European-Sleep-Research-Society, Sep 2012, Paris, France. 21, pp.326, 2012

Poster de conférence hal-02369336v1