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SLAP controls mTORC2 integrity via UBE3C-mediated non-degradative mLST8 ubiquitination to suppress colorectal tumorigenesis
Rudy Mevizou
,
Dana Naim
,
Florent Cauchois
,
Cécile Naudin
,
Georgia Greaves
et al.
Article dans une revue
hal-05421846v1
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Lipid-driven Src self-association modulates its transformation capacity
Irrem-Laareb Mohammad
,
Marina I Giannotti
,
Elise Fourgous
,
Yvan Boublik
,
Alejandro Fernández
et al.
Article dans une revue
hal-05317927v1
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Progastrin Promotes Colorectal Cancer Stem Cell‐Like Properties via the Receptor PZR
Julie Nguyen
,
Marie Lafitte
,
Maud Barbery
,
Kevin Espie
,
Maya Jeitany
et al.
Article dans une revue
hal-05213630v1
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Regulation of Src tumor activity by its N-terminal intrinsically disordered region
Emilie Aponte
,
Marie Lafitte
,
Audrey Sirvent
,
Valérie Simon
,
Maud Barbery
et al.
Article dans une revue
hal-03523417v1
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Oncogenic Signalling of PEAK2 Pseudokinase in Colon Cancer
Céline Lecointre
,
Elise Fourgous
,
Ingrid Montarras
,
Clément Kerneur
,
Valérie Simon
et al.
Article dans une revue
hal-05086826v1
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New functions of DDR1 collagen receptor in tumor dormancy, immune exclusion and therapeutic resistance
Audrey Sirvent
,
Kevin Espie
,
Evangelia Papadopoulou
,
Dana Naim
,
Serge Roche
Article dans une revue
hal-03830459v1
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SHED-Dependent Oncogenic Signaling of the PEAK3 Pseudo-Kinase
Youcef Ounoughene
,
Elise Fourgous
,
Yvan Boublik
,
Estelle Saland
,
Nathan Guiraud
et al.
Article dans une revue
hal-03515387v1
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Src Family Tyrosine Kinases in Intestinal Homeostasis, Regeneration and Tumorigenesis
Audrey Sirvent
,
Rudy Mevizou
,
Dana Naim
,
Marie Lafitte
,
Serge Roche
Article dans une revue
hal-02989641v1
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Collagen Kinase Receptors as Potential Therapeutic Targets in Metastatic Colon Cancer
Marie Lafitte
,
Audrey Sirvent
,
Serge Roche
Article dans une revue
hal-02989658v1
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Roles of exosomes in metastatic colorectal cancer
Marie Lafitte
,
Céline Lecointre
,
Serge Roche
Article dans une revue
hal-02339517v1
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Control of Tyrosine Kinase Signalling by Small Adaptors in Colorectal Cancer
Rudy Mevizou
,
Audrey Sirvent
,
Serge Roche
Article dans une revue
hal-02339136v1
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DDR1 inhibition as a new therapeutic strategy for colorectal cancer
Audrey Sirvent
,
Marie Lafitte
,
Serge Roche
Article dans une revue
hal-01905024v1
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Inhibition of DDR1-BCR signalling by nilotinib as a new therapeutic strategy for metastatic colorectal cancer
Maya Jeitany
,
Cédric Leroy
,
Priscillia Tosti
,
Marie Lafitte
,
Jordy Le Guet
et al.
Article dans une revue
hal-01872978v1
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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation
Céline Lecointre
,
Valérie Simon
,
Clément Kerneur
,
Frédéric Allemand
,
Aurélie Fournet
et al.
Article dans une revue
hal-01872982v1
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The Unique Domain Forms a Fuzzy Intramolecular Complex in Src Family Kinases
Miguel Arbesú
,
Mariano Maffei
,
Tiago N. Cordeiro
,
João M.C. Teixeira
,
Yolanda Pérez
et al.
Article dans une revue
hal-01875247v1
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Syntenin mediates SRC function in exosomal cell-to-cell communication
Naga Sailaja Imjeti
,
Kerstin Menck
,
Antonio Luis Egea-Jimenez
,
Céline Lecointre
,
Frédérique Lembo
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (47), pp.12495 - 12500. ⟨10.1073/pnas.1713433114⟩
Article dans une revue
hal-01765373v1
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The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer
Cécile Naudin
,
Clément Chevalier
,
Serge Roche
Article dans une revue
inserm-01292961v1
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Vesicular trafficking regulators are new players in breast cancer progression: Role of TOM1L1 in ERBB2-dependent invasion
Clément Chevalier
,
Serge Roche
,
Christine Bénistant
Article dans une revue
hal-01878026v1
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TOM1L1 drives membrane delivery of MT1-MMP to promote ERBB2-induced breast cancer cell invasion
Clément Chevalier
,
Guillaume Collin
,
Simon Descamps
,
Heiani Touaitahuata
,
Valérie Simon
et al.
Article dans une revue
hal-01299292v1
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YES oncogenic activity is specified by its SH4 domain and regulates RAS/MAPK signaling in colon carcinoma cells
Fanny Dubois
,
Cédric Leroy
,
Valérie Simon
,
Christine Benistant
,
Serge Roche
American Journal of Cancer Research, 2015, 5 (6), pp.1972--1987
Article dans une revue
hal-01883466v1
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The SH3 Domain Acts as a Scaffold for the N-Terminal Intrinsically Disordered Regions of c-Src
Mariano Maffei
,
Miguel Arbesú
,
Anabel-Lise Le~roux
,
Irene Amata
,
Serge Roche
et al.
Article dans une revue
hal-01883500v1
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Progastrin a new pro-angiogenic factor in colorectal cancer
S Najib
,
A Kowalski-Chauvel
,
C Do
,
S Roche
,
E Cohen-Jonathan-Moyal
et al.
Article dans une revue
hal-01883491v1
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ABL Tyrosine Kinase Inhibition Variable Effects on the Invasive Properties of Different Triple Negative Breast Cancer Cell Lines
Clément Chevalier
,
Aude Cannet
,
Simon Descamps
,
Audrey Sirvent
,
Valérie Simon
et al.
Article dans une revue
hal-01883471v1
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CBL controls a tyrosine kinase network involving AXL, SYK and LYN in nilotinib-resistant chronic myeloid leukaemia: CBL controls kinase expression
Romain Gioia
,
Claire Trégoat
,
Pierre-Yves Dumas
,
Valérie Lagarde
,
Valérie Prouzet-Mauléon
et al.
Article dans une revue
istex
hal-01883494v1
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Contribution of phosphoproteomics in understanding SRC signaling in normal and tumor cells
Audrey Sirvent
,
Serge Urbach
,
Serge Roche
Article dans une revue
istex
hal-01883488v1
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SLAP displays tumour suppressor functions in colorectal cancer via destabilization of the SRC substrate EPHA2
Cécile Naudin
,
Audrey Sirvent
,
Cédric Leroy
,
Romain Larive
,
Valérie Simon
et al.
Article dans une revue
hal-01944933v1
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Analyse in vivo de la signalisation tumorale induite par les tyrosinekinases par protéomique quantitative
Audrey Sirvent
,
Serge Urbach
,
Serge Roche
Article dans une revue
hal-01942937v1
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The short form of RON is expressed in acute myeloid leukemia and sensitizes leukemic cells to cMET inhibitors
C Fialin
,
C Larrue
,
F Vergez
,
J Sarry
,
S Bertoli
et al.
Article dans une revue
hal-04784565v1
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Specific Oncogenic Activity of the Src-Family Tyrosine Kinase c-Yes in Colon Carcinoma Cells.
Florence Sancier
,
Aurélie Dumont
,
Audrey Sirvent
,
Ludmilla Paquay de Plater
,
Thomas Edmonds
et al.
Article dans une revue
hal-00581348v1
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Src family tyrosine kinases-driven colon cancer cell invasion is induced by Csk membrane delocalization.
Audrey Sirvent
,
C. Bénistant
,
Julie Pannequin
,
L. Veracini
,
V. Simon
et al.
Article dans une revue
hal-00443776v1
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Quantitative phosphoproteomics reveals a cluster of tyrosine kinases that mediates SRC invasive activity in advanced colon carcinoma cells.
Cédric Leroy
,
Camille Fialin
,
Audrey Sirvent
,
Valérie Simon
,
Serge Urbach
et al.
Article dans une revue
hal-00367875v1
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Evidence that Resistance to Nilotinib May Be Due to BCR-ABL, Pgp, or Src Kinase Overexpression
François-Xavier Mahon
,
Sandrine Hayette
,
Valérie Lagarde
,
Francis Belloc
,
Béatrice Turcq
et al.
Article dans une revue
hal-03155362v1
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Cytoplasmic signalling by the c-Abl tyrosine kinase in normal and cancer cells.
Audrey Sirvent
,
Christine Benistant
,
Serge Roche
Article dans une revue
hal-00346793v1
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The Src-like adaptor protein regulates PDGF-induced actin dorsal ruffles in a c-Cbl-dependent manner.
Audrey Sirvent
,
C. Leroy
,
A. Boureux
,
V. Simon
,
Serge Roche
Article dans une revue
hal-00211547v1
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The Csk-binding protein PAG regulates PDGF-induced Src mitogenic signaling via GM1.
Laurence Veracini
,
Valérie Simon
,
Véronique Richard
,
Burkhart Schraven
,
Vaclav Horejsi
et al.
Article dans une revue
hal-00348407v1
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The tyrosine kinase Abl is required for Src-transforming activity in mouse fibroblasts and human breast cancer cells.
Audrey Sirvent
,
A. Boureux
,
V. Simon
,
C. Leroy
,
Serge Roche
Article dans une revue
hal-00189107v1
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|
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The Tom1L1-clathrin heavy chain complex regulates membrane partitioning of the tyrosine kinase Src required for mitogenic and transforming activities.
Guillaume Collin
,
Mélanie Franco
,
Valérie Simon
,
Christine Bénistant
,
Serge Roche
Article dans une revue
hal-00189124v1
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A Function for Phosphoinositide 3-Kinase β Lipid Products in Coupling βγ to Ras Activation in Response to Lysophosphatidic Acid
Armelle Yart
,
Serge Roche
,
Reinhard Wetzker
,
Muriel Laffargue
,
Nicholas Tonks
et al.
Article dans une revue
hal-03191860v1
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A Critical Role for Phosphoinositide 3-Kinase Upstream of Gab1 and SHP2 in the Activation of Ras and Mitogen-activated Protein Kinases by Epidermal Growth Factor
Armelle Yart
,
Muriel Laffargue
,
Patrick Mayeux
,
Stany Chretien
,
Christine Pérès
et al.
Article dans une revue
hal-03191837v1
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|
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An Epidermal Growth Factor Receptor/Gab1 Signaling Pathway Is Required for Activation of Phosphoinositide 3-Kinase by Lysophosphatidic Acid
Muriel Laffargue
,
Patrick Raynal
,
Armelle Yart
,
Christine Pérès
,
Bernard Payrastre
et al.
Article dans une revue
hal-03192161v1
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A Function for Phosphatidylinositol 3-Kinase β (p85α-p110β) in Fibroblasts during Mitogenesis: Requirement for Insulin- and Lysophosphatidic Acid-Mediated Signal Transduction
Serge Roche
,
J. Downward
,
Patrick Raynal
,
Sara Courtneidge
Article dans une revue
hal-03191846v1
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