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Role of symmetry in 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as inhibitors of translation initiation
Hongwei Yang
,
Ting Chen
,
Séverine Denoyelle
,
Limo Chen
,
Jing Fan
Article dans une revue
hal-04119175v1
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Growth hormone secretagogues modulate inflammation and fibrosis in mdx mouse model of Duchenne muscular dystrophy
Brigida Boccanegra
,
Ornella Cappellari
,
Paola Mantuano
,
Daniela Trisciuzzi
,
Antonietta Mele
Article dans une revue
hal-04121024v1
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GHSR controls food deprivation-induced activation of CRF neurons of the hypothalamic paraventricular nucleus in a LEAP2-dependent manner
Gimena Fernandez
,
Agustina Cabral
,
Pablo de Francesco
,
Maia Uriarte
,
Mirta Reynaldo
Article dans une revue
hal-04044157v1
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A Novel Truncated Liver Enriched Antimicrobial Peptide-2 Palmitoylated at its N-Terminal Antagonizes Effects of Ghrelin
Lucie Holá
,
Blanka Železná
,
Alena Karnošová
,
Jaroslav Kuneš
,
Jean-Alain Fehrentz
Article dans une revue
hal-04119343v1
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Design and characterization of a triazole-based growth hormone secretagogue receptor modulator inhibiting the glucoregulatory and feeding actions of ghrelin
Sylvie Péraldi-Roux
,
Morgane Bayle
,
Céline M'Kadmi
,
Marjorie Damian
,
Justine Vaillé
Article dans une revue
hal-03813988v1
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LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling
Emilio Mustafá
,
Santiago Cordisco González
,
Marjorie Damian
,
Sonia Cantel
,
Severine Denoyelle
Article dans une revue
hal-03382623v1
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Allosteric modulation of ghrelin receptor signaling by lipids
Marjorie Damian
,
Maxime Louet
,
Antoniel Augusto Severo Gomes
,
Céline M’kadmi
,
Séverine Denoyelle
Article dans une revue
hal-03852471v1
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Allosteric modulation of ghrelin receptor signaling by lipids
Marjorie Damian
,
Maxime Louet
,
Antoniel Augusto Severo Gomes
,
Céline M’kadmi
,
Séverine Denoyelle
Article dans une revue
hal-03407522v1
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Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
Maxime Louet
,
Marina Casiraghi
,
Marjorie Damian
,
Mauricio Gs Costa
,
Pedro Renault
Article dans une revue
hal-03407524v1
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Development of non-peptidic inverse agonists of the ghrelin receptor (GHSR) based on the 1,2,4-triazole scaffold
Khoubaib Ben Haj Salah
,
Mathieu Maingot
,
Anne-Laure Blayo
,
Céline M'Kadmi
,
Marjorie Damian
Article dans une revue
hal-03027489v1
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Development of a novel fluorescent ligand of growth hormone secretagogue receptor based on the N-Terminal Leap2 region
Franco Barrile
,
Céline M'Kadmi
,
Pablo de Francesco
,
Agustina Cabral
,
Guadalupe García Romero
Article dans une revue
hal-02375522v1
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Evaluation of amidoxime derivatives as prodrug candidates of potent bis-cationic antimalarials
Olivier Berger
,
Stéphanie Ortial
,
Sharon Wein
,
Séverine Denoyelle
,
Françoise Bressolle
Article dans une revue
hal-03488325v1
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N-Terminal Liver-Expressed Antimicrobial Peptide 2 (LEAP2) Region Exhibits Inverse Agonist Activity toward the Ghrelin Receptor
Céline M'Kadmi
,
Agustina Cabral
,
Franco Barrile
,
Julien Giribaldi
,
Sonia Cantel
Article dans une revue
hal-02307053v1
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Synthesis of [1,2,4]Triazolo[4,3- a ]piperazin-6-ones: An Approach to the Triazole-Fused Ketopiperazine Scaffold
Khoubaib Ben Haj Salah
,
Baptiste Legrand
,
Mathieu Bibian
,
Emmanuel Wenger
,
Jean-Alain Fehrentz
Article dans une revue
hal-02871181v1
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GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation
Marjorie Damian
,
Véronique Pons
,
Pedro Renault
,
Céline M’kadmi
,
Bartholomé Delort
Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (17), pp.4501-4506. ⟨10.1073/pnas.1712725115⟩
Article dans une revue
hal-02322168v1
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New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center
Mathieu Maingot
,
Anne-Laure Blayo
,
Severine Denoyelle
,
Céline M’kadmi
,
Marjorie Damian
Article dans une revue
hal-02871896v1
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Synthesis of Thieno[3,2- e ][1,4]diazepin-2-ones: Application of an Uncatalysed Pictet-Spengler Reaction
Séverine Denoyelle
,
Guillaume Tambutet
,
Nicolas Masurier
,
Ludovic Maillard
,
Jean Martinez
Article dans une revue
hal-03563932v1
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Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex.
Marjorie Damian
,
Sophie Mary
,
Mathieu Maingot
,
Céline M'Kadmi
,
Didier Gagne
Proceedings of the National Academy of Sciences of the United States of America, 2015, 112 (5), pp.1601-1606. ⟨10.1073/pnas.1414618112⟩
Article dans une revue
hal-01115392v1
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New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.
Anne-Laure Blayo
,
Mathieu Maingot
,
Babette Aicher
,
Céline M'Kadmi
,
Peter Schmidt
Article dans une revue
hal-01090274v1
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Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling
Céline M'Kadmi
,
Jean-Philippe Leyris
,
Lauriane Onfroy
,
Céline Galés
,
Aude Saulière
Article dans une revue
hal-03564155v1
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The 1,2,4-triazole as a scaffold for the design of ghrelin receptor ligands: development of JMV 2959, a potent antagonist
Aline Moulin
,
Luc Brunel
,
Damien Boeglin
,
Luc Demange
,
Johanne Ryan
Article dans une revue
hal-02871938v1
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Synthesis and SAR study of novel 3,3-diphenyl-1,3-dihydroindol-2-one derivatives as potent eIF2·GTP·Met-tRNAiMet ternary complex inhibitors
Séverine Denoyelle
,
Ting Chen
,
Hongwei Yang
,
Limo Chen
,
Yingzhen Zhang
Article dans une revue
hal-03562672v1
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Selective C-Acylation of 2-Aminoimidazo[1,2- a ]pyridine: Application to the Synthesis of Imidazopyridine-Fused [1,3]Diazepinones
Nicolas Masurier
,
Roberta Aruta
,
Vincent Gaumet
,
Séverine Denoyelle
,
Emmanuel Moreau
Article dans une revue
hal-01677551v1
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In vitro inhibition of translation initiation by N,N′-diarylureas—potential anti-cancer agents
Séverine Denoyelle
,
Ting Chen
,
Limo Chen
,
Yibo Wang
,
Edvin Klosi
Article dans une revue
hal-04118217v1
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Tumor suppression by small molecule inhibitors of translation initiation
Limo Chen
,
Bertal Aktas
,
Yibo Wang
,
Xiaoying He
,
Rupam Sahoo
Article dans une revue
hal-04121321v1
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Chemical genetics identify eIF2α kinase heme-regulated inhibitor as an anticancer target
Ting Chen
,
Duygu Ozel
,
Yuan Qiao
,
Fred Harbinski
,
Limo Chen
Article dans une revue
hal-04119403v1
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Synthesis and evaluation of hybrid bis-cationic salts as antimalarial drugs
Stéphanie Ortial
,
Severine Denoyelle
,
Sharon Wein
,
Olivier Berger
,
Thierry Durand
Article dans une revue
hal-00448020v1
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A structure–activity investigation of hemifluorinated bifunctional bolaamphiphiles designed for gene delivery
Mélanie Brunelle
,
Ange Polidori
,
Séverine Denoyelle
,
Anne-Sylvie Fabiano
,
Pascal Vuillaume
Article dans une revue
hal-04119298v1
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Design and synthesis of amidoxime derivatives for orally potent C-alkylamidine-based antimalarial agents
Mahama Ouattara
,
Sharon Wein
,
Séverine Denoyelle
,
Stéphanie Ortial
,
Thierry Durand
Article dans une revue
hal-03530218v1
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Synthesis and preliminary biological studies of hemifluorinated bifunctional bolaamphiphiles designed for gene delivery
Séverine Denoyelle
,
Ange Polidori
,
Mélanie Brunelle
,
Pascal Vuillaume
,
Sylvette Laurent
Article dans une revue
hal-04119479v1
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