|
Genetic Background Influence on Hippocampal Synaptic Plasticity: Frequency-Dependent Variations between an Inbred and an Outbred Mice Strain
Candice Roux
,
Pierre Lecouflet
,
Jean-Marie Billard
,
Elise Esneault
,
Marianne Leger
Journal articles
hal-04212361v1
|
|
5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition
Caroline Lahogue
,
Jean-Marie Billard
,
Thomas Freret
,
Valentine Bouet
Journal articles
hal-04089829v1
|
|
Improved NMDA Receptor Activation by the Secreted Amyloid-Protein Precursor-α in Healthy Aging: A Role for D-Serine?
Jean-Marie Billard
,
Thomas Freret
Journal articles
hal-03910923v1
|
|
Association between road traffic accidents and drugs belonging to the antiseizure medications class: A pharmacovigilance analysis in VigiBase
Basile Chrétien
,
Sophie Nguyen
,
Charles Dolladille
,
Pierre‐marie Morice
,
Marie Heraudeau
Journal articles
hal-03832961v1
|
|
Dopaminergic neuromodulation of prefrontal cortex activity requires the NMDA receptor co-agonist D-serine
Glenn Dallérac
,
Xia Li
,
Pierre Lecouflet
,
Nadège Morisot
,
Silvia Sacchi
Proceedings of the National Academy of Sciences of the United States of America, 2021, 118 (23), pp.e2023750118. ⟨10.1073/pnas.2023750118⟩
Journal articles
hal-03331836v1
|
|
Interplay between 5-HT4 receptors and GABAergic system within CA1 hippocampal synaptic plasticity
Pierre Lecouflet
,
Candice Roux
,
B Potier
,
Marianne Leger
,
Elie Brunet
Journal articles
hal-03371418v1
|
|
Functional Dysregulations in CA1 Hippocampal Networks of a 3-Hit Mouse Model of Schizophrenia
Solenn Percelay
,
Jean-Marie Billard
,
Thomas Freret
,
Annie Andrieux
,
Michel Boulouard
Journal articles
hal-03238069v1
|
|
A new 3-hit mouse model of schizophrenia built on genetic, early and late factors
Valentine Bouet
,
Solenn Percelay
,
Elise Leroux
,
Boubacar Diarra
,
Marianne Léger
Journal articles
hal-04212366v1
|
|
Memory Disorders Related to Hippocampal Function: The Interest of 5-HT4Rs Targeting
Candice Roux
,
Marianne Leger
,
Thomas Freret
Journal articles
hal-03471906v1
|
|
Fast Anxiolytic-Like Effect Observed in the Rat Conditioned Defensive Burying Test, after a Single Oral Dose of Natural Protein Extract Products
Thomas Freret
,
Stacy Largilliere
,
Gerald Nee
,
Melanie Coolzaet
,
Sophie Corvaisier
Journal articles
hal-03471908v1
|
|
Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer’s disease
François-Xavier Toublet
,
Julien Lalut
,
Bérénice Hatat
,
Cédric Lecoutey
,
Audrey Davis
Journal articles
hal-03082877v1
|
|
Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis
Lou Rizzolo
,
Marianne Leger
,
Sophie Corvaisier
,
Mathilde Groussard
,
Hervé Platel
Journal articles
hal-03019700v1
|
|
Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network
Eva Ploux
,
Valentine Bouet
,
Inna Radzishevsky
,
Herman Wolosker
,
Thomas Freret
Journal articles
hal-03072318v1
|
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Author Correction: Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise
Tristan Martin
,
Yves Dauvilliers
,
Ouma-Chandrou Koumar
,
Valentine Bouet
,
Thomas Freret
Journal articles
hal-03518966v1
|
|
Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity
Pierre Lecouflet
,
Candice M. Roux
,
Brigitte Potier
,
Marianne Leger
,
Elie Brunet
Journal articles
hal-03040826v1
|
|
Antipsychotic lurasidone: Behavioural and pharmacokinetic data in C57BL/6 mice
Solenn Percelay
,
Marc Since
,
S. Lagadu
,
Thomas Freret
,
Valentine Bouet
Journal articles
hal-03602034v1
|
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Donecopride, a Swiss army knife with potential interest against Alzheimer's disease
Christophe Rochais
,
Cédric Lecoutey
,
Katia Hamidouche
,
Patrizia Giannoni
,
Florence Gaven
Journal articles
hal-02428730v1
|
|
D-serine in physiological and pathological brain aging
E. Ploux
,
T Freret
,
Jean-Marie Billard
Journal articles
hal-02947335v1
|
|
A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer’s Disease
Bérénice Hatat
,
Samir Yahiaoui
,
Cédric Lecoutey
,
Audrey Davis
,
Thomas Freret
Journal articles
hal-02399864v1
|
|
Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise
Tristan Martin
,
Yves Dauvilliers
,
Ouma-Chandrou Koumar
,
Valérie Bouet
,
Thomas Freret
Journal articles
hal-02400711v1
|
|
Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer’s Disease
François-Xavier Toublet
,
Cédric Lecoutey
,
Julien Lalut
,
Bérénice Hatat
,
Audrey Davis
Journal articles
hal-02399906v1
|
|
Characterizing age-related decline of recognition memory and brain activation profile in mice
Hassina Belblidia
,
Marianne Leger
,
Abdelmalek Abdelouadoud
,
Anne Quiedeville
,
Floriane Calocer
Journal articles
hal-01733066v1
|
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Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice
Eva Lhuissier
,
Juliette Aury-Landas
,
Valentine Bouët
,
Céline Bazille
,
Yohann Repesse
Journal articles
hal-01796395v1
|
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Asc-1 transporter activation: an alternative to rescue age-related alterations in functional plasticity at rat hippocampal CA3/CA1 synapses
Jean-Marie Billard
,
Thomas Freret
Journal articles
hal-02135230v1
|
|
Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate
Anouk Schrantee
,
Jordi Tremoleda
,
Marzena Wylezinska-Arridge
,
Valentine Bouet
,
Peter Hesseling
Journal articles
hal-02135218v1
|
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Co-modulation of an allosteric modulator of nicotinic receptor-cholinesterase inhibitor (galantamine) and a 5-HT4 receptor agonist (RS-67333): effect on scopolamine-induced memory deficit in the mouse
Thomas Freret
,
Véronique Lelong-Boulouard
,
Pierre Lecouflet
,
Katia Hamidouche
,
François Dauphin
Journal articles
hal-02135214v1
|
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Deletion of the serotonin receptor type 7 disrupts the acquisition of allocentric but not egocentric navigation strategies in mice
Gregory Beaudet
,
Christelle Jozet-Alves
,
Rachel Asselot
,
Pascale Schumann-Bard
,
Thomas Freret
Journal articles
hal-01472663v1
|
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LP-211, a selective 5-HT 7 receptor agonist, increases novelty-preference and promotes risk-prone behavior in rats
G. Beaudet
,
E. Paizanis
,
F. Zoratto
,
E. Lacivita
,
M. Leopoldo
Journal articles
hal-02193575v1
|
|
Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT 4 R) partial agonist and 5-HT 6 R antagonist activities, as potential treatment of Alzheimer’s disease
Samir Yahiaoui
,
Katia Hamidouche
,
Céline Ballandonne
,
Audrey Davis
,
Jana Sopkova-de Oliveira Santos
Journal articles
hal-02043759v1
|
|
Long-Lasting Effects of Chronic Intermittent Alcohol Exposure in Adolescent Mice on Object Recognition and Hippocampal Neuronal Activity.
G Beaudet
,
S Valable
,
J Bourgine
,
V Lelong-Boulouard
,
L Lanfumey
Journal articles
hal-01576066v1
|
|
Mechanisms underlying the neuroprotective effect of brain reserve against late life depression
Thomas Freret
,
Pierrette Gaudreau
,
Pascale Schumann-Bard
,
Jean-Marie Billard
,
Aurel Popa-Wagner
Journal articles
hal-02325092v1
|
|
Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors
Gregory Beaudet
,
Valentine Bouet
,
Christelle Jozet-Alves
,
Pascale Schumann-Bard
,
Francois Dauphin
Journal articles
hal-01472654v1
|
|
Environmental Enrichment Duration Differentially Affects Behavior and Neuroplasticity in Adult Mice
Marianne Leger
,
Eleni Paizanis
,
Kwamivi Dzahini
,
Anne Quiedeville
,
Valentine Bouet
Journal articles
hal-02135292v1
|
|
Therapeutic Potential of 5-HT 6 Receptor Agonists
Delphine Karila
,
Thomas Freret
,
Valentine Bouet
,
Michel Boulouard
,
Patrick Dallemagne
Journal articles
hal-02043781v1
|
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Time decay of object, place and temporal order memory in a paradigm assessing simultaneously episodic-like memory components in mice
Hassina Belblidia
,
Abdelmalek Abdelouadoud
,
Christelle Jozet-Alves
,
Hélène Dumas
,
Thomas Freret
Journal articles
hal-01472655v1
|
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Usefulness of Time-Point Serum Cortisol and ACTH Measurements for the Adjustment of Glucocorticoid Replacement in Adrenal Insufficiency
Elise Rousseau
,
Michael Joubert
,
Géraldine Trzepla
,
Jean Jacques Parienti
,
Thomas Freret
Journal articles
hal-02190958v1
|
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride
Cédric Lecoutey
,
Cédric Lecoutey
,
Florence Gaven
,
Patrizia Giannoni
,
Katia Hamidouche
Journal articles
hal-02043873v1
|
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Effects of long-term methylphenidate treatment in adolescent and adult rats on hippocampal shape, functional connectivity and adult neurogenesis
K. van Der Marel
,
V. Bouet
,
G.F. Meerhoff
,
T. Freret
,
M. Boulouard
Journal articles
hal-02193376v1
|
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Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances
Anne Quiedeville
,
Michel Boulouard
,
Katia Hamidouche
,
Virginie da Silva Costa-Aze
,
Gerald Nee
Journal articles
hal-02043824v1
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Effects of acute administration of melatonin on attentional, executive, and working memory processes in rats
Christophe Liet
,
Fella Amenouche
,
Thomas Freret
,
Michel Boulouard
,
Benoit Mauvieux
Journal articles
hal-02193380v1
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Iron overload accelerates neuronal amyloid-β production and cognitive impairment in transgenic mice model of Alzheimer's disease
Javier Becerril-Ortega
,
Karim Bordji
,
Thomas Freret
,
Travis Rush
,
Alain Buisson
Journal articles
hal-01626647v1
|
|
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment
Cédric Lecoutey
,
Damien Hedou
,
Thomas Freret
,
Patrizia Giannoni
,
Florence Gaven
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Journal articles
hal-01800439v2
|
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Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology.
Alban Lepailleur
,
Thomas Freret
,
Stéphane Lemaître
,
Michel Boulouard
,
François Dauphin
Journal of Chemical Information and Modeling, 2014, 54 (6), pp.1773-1784
Journal articles
hal-01064770v1
|
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New orally effective 3-(2-nitro)phenylpropanamide analgesic derivatives: Synthesis and antinociceptive evaluation
Marc Since
,
Thomas Freret
,
Gerald Nee
,
Thierry Terme
,
Patrice Vanelle
Journal articles
hal-01460473v1
|
|
Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging
Véronique Paban
,
Jean-Marie Billard
,
Valentine Bouet
,
Thomas Freret
,
Michel Boulouard
Journal articles
hal-02325134v1
|
|
Object recognition test in mice
Marianne Leger
,
Anne Quiedeville
,
Valentine Bouet
,
Benoît Haelewyn
,
Michel Boulouard
Journal articles
hal-02135259v1
|
|
Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT4 receptor activation (RS67333) on object recognition in mice.
Thomas Freret
,
Valentine Bouet
,
Anne Quiedeville
,
Gerald Nee
,
Patrick Dallemagne
Behavioural Brain Research, 2012, 230, pp.304-308
Journal articles
hal-00821461v1
|
|
Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations.
Annelise Letourneur
,
Thomas Freret
,
Simon Roussel
,
Michel Boulouard
,
Didier Divoux
Journal articles
hal-00862822v1
|
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Environmental enrichment improves recent but not remote memory in association with a modified brain metabolic activation profile in adult mice.
Marianne Leger
,
Valentine Bouet
,
Thomas Freret
,
Anne-Sophie Darmaillacq
,
Matthieu Dacher
Journal articles
hal-00862779v1
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|
Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment.
Valentine Bouet
,
Anne Klomp
,
Thomas Freret
,
Marzena Wylezinska-Arridge
,
Jordi Lopez-Tremoleda
Journal articles
hal-00862306v1
|
|
Post-stroke depression: mechanisms, translation and therapy.
Isabelle Loubinoux
,
Golo Kronenberg
,
Matthias Endres
,
Pascale Schumann-Bard
,
Thomas Freret
Journal articles
hal-00862834v1
|
|
Repeated mild hypoxic exposures decrease anxiety-like behavior in the adult mouse together with an increased brain adrenomedullin gene expression.
Claire Leconte
,
Marianne Léger
,
Michel Boulouard
,
Emmanuelle Tixier
,
Thomas Fréret
Journal articles
hal-00862777v1
|
|
Environmental enrichment enhances episodic-like memory in association with a modified neuronal activation profile in adult mice.
Marianne Leger
,
Anne Quiedeville
,
Eleni Paizanis
,
Sharuja Natkunarajah
,
Thomas Freret
Journal articles
hal-00862786v1
|
|
Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.
Thomas Freret
,
Valentine Bouet
,
Anne Quiedeville
,
Gérald Nee
,
Patrick Dallemagne
Journal articles
hal-00862757v1
|
|
Influence of anxiety in spatial memory impairments related to the loss of vestibular function in rat.
M. L. Machado
,
V. Lelong-Boulouard
,
P. F. Smith
,
T. Freret
,
B. Philoxene
Journal articles
hal-00866396v1
|
|
A biphasic and brain-region selective down-regulation of cyclic adenosine monophosphate concentrations supports object recognition in the rat.
Maïte Hotte
,
François Dauphin
,
Thomas Freret
,
Michel Boulouard
,
Guenaëlle Levallet
Journal articles
hal-00862771v1
|
|
Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.
Lydia Danglot
,
Thomas Freret
,
Nicolas Le Roux
,
Nicolas Narboux Nême
,
Andrea Burgo
Journal articles
hal-00776396v1
|
|
Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan.
T. Freret
,
J.-M. Billard
,
P. Schumann-Bard
,
P. Dutar
,
F. Dauphin
Journal articles
hal-00866400v1
|
|
Rescue of cognitive aging by long-lasting environmental enrichment exposure initiated before median lifespan
T. Freret
,
Jean-Marie Billard
,
P. Schumann-Bard
,
P. Dutar
,
F. Dauphin
Journal articles
hal-02325180v1
|
|
Influence of vestibular input on spatial and nonspatial memory and on hippocampal NMDA receptors.
S. Besnard
,
M. L. Machado
,
G. Vignaux
,
M. Boulouard
,
A. Coquerel
Journal articles
hal-00866441v1
|
|
Spatial and non-spatial performance in mutant mice devoid of otoliths.
M. L. Machado
,
N. Kroichvili
,
T. Freret
,
B. Philoxène
,
V. Lelong-Boulouard
Journal articles
hal-00866394v1
|
|
Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging.
Véronique Paban
,
Jean-Marie Billard
,
Valentine Bouet
,
Thomas Freret
,
Michel Boulouard
Journal articles
hal-00862299v1
|
|
Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice.
Valentine Bouet
,
Blandine Lecrux
,
Gwenaelle Tran
,
Thomas Freret
Journal articles
hal-00862841v1
|
|
Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals
Valentine Bouet
,
Thomas Freret
,
Patrick Dutar
,
Jean-Marie Billard
,
Michel Boulouard
Journal articles
hal-02325196v1
|
|
On the importance of long-term functional assessment after stroke to improve translation from bench to bedside.
Thomas Freret
,
Pascale Schumann-Bard
,
Michel Boulouard
,
Valentine Bouet
Journal articles
hal-00862997v1
|
|
Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals.
Valentine Bouet
,
Thomas Freret
,
Patrick Dutar
,
Jean-Marie Billard
,
Michel Boulouard
Journal articles
hal-00862993v1
|
|
Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat.
Valentine Bouet
,
Thomas Freret
,
Steve Ankri
,
Madeleine Bezault
,
Sylvain Renolleau
Journal articles
hal-00863083v1
|
|
Delayed hypoxic postconditioning protects against cerebral ischemia in the mouse.
Claire Leconte
,
Emmanuelle Tixier
,
Thomas Freret
,
Jérôme Toutain
,
Romaric Saulnier
Journal articles
hal-00863295v1
|
|
The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice.
Valentine Bouet
,
Michel Boulouard
,
Jérôme Toutain
,
Didier Divoux
,
Myriam Bernaudin
Journal articles
hal-00863258v1
|
|
Tetrahydroisoquinolines as dopaminergic ligands: 1-Butyl-7-chloro-6-hydroxy-tetrahydroisoquinoline, a new compound with antidepressant-like activity in mice.
Inmaculada Berenguer
,
Noureddine El Aouad
,
Sebastián Andujar
,
Vanessa Romero
,
Fernando Suvire
Journal articles
hal-00863255v1
|
|
Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.
Thomas Freret
,
Valentine Bouet
,
Claire Leconte
,
Simon Roussel
,
Laurent Chazalviel
Journal articles
hal-00863264v1
|
|
Combined therapeutic strategy using erythropoietin and mesenchymal stem cells potentiates neurogenesis after transient focal cerebral ischemia in rats.
Elise Esneault
,
Emilie Pacary
,
Dauphou Eddi
,
Thomas Freret
,
Emmanuelle Tixier
Journal articles
hal-00863330v1
|
|
Intraluminal thread model of focal stroke in the non-human primate
Thomas Freret
,
Valentine Bouet
,
Jérôme Toutain
,
Romaric Saulnier
,
Palma Pro-Sistiaga
Journal articles
hal-00863332v1
|
|
Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse.
Benoît Haelewyn
,
Thomas Freret
,
Emilie Pacary
,
Pascale Schumann-Bard
,
Michel Boulouard
Journal articles
hal-00178443v1
|
|
Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.
Valentine Bouët
,
Thomas Freret
,
Jérôme Toutain
,
Didier Divoux
,
Michel Boulouard
Journal articles
hal-00178296v1
|
|
Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse
Benoît Haelewyn
,
Thomas Freret
,
Emilie Pacary
,
Pascale Schumann-Bard
,
Michel Boulouard
Journal articles
hal-00867870v1
|
|
Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse
Valentine Bouet
,
Thomas Freret
,
J. Toutain
,
Didier Divoux
,
Michel Boulouard
Journal articles
hal-00867774v1
|
|
Long-term functional outcome following transient middle cerebral artery occlusion in the rat: correlation between brain damage and behavioral impairment.
Thomas Freret
,
Laurent Chazalviel
,
Simon Roussel
,
Myriam Bernaudin
,
Pascale Schumann-Bard
Journal articles
hal-00865366v1
|
|
Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.
T. Freret
,
S. Valable
,
L. Chazalviel
,
R. Saulnier
,
E.T. Mackenzie
European Journal of Neuroscience, 2006, 23, pp.1757-1765
Journal articles
hal-00023477v1
|
|
Delayed administration of deferoxamine reduces brain damage and promotes functional recovery after transient focal cerebral ischemia in the rat.
Thomas Freret
,
Samuel Valable
,
Laurent Chazalviel
,
Romaric Saulnier
,
Eric T Mackenzie
Journal articles
hal-00865370v1
|
|
Effect of hypoxic preconditioning on brain genomic response before and following ischemia in the adult mouse: identification of potential neuroprotective candidates for stroke
Y. Tang
,
E. Pacary
,
T. Freret
,
D. Divoux
,
E. Petit
Neurobiology of Disease, 2006, 21, pp.18-28
Journal articles
hal-00018635v1
|