Valentine BOUET

72
Documents

Domaines de recherche

Neurosciences Neurobiologie Pharmacologie

Publications

Publications

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A new 2-hit model combining serine racemase deletion and maternal separation displays behavioral and cognitive deficits associated with schizophrenia

Caroline Lahogue , Michel Boulouard , François Menager , Thomas Freret , Jean-Marie Billard et al.
Behavioural Brain Research, 2025, 477, ⟨10.1016/j.bbr.2024.115301⟩
Article dans une revue hal-04771860 v1

The 3-hit animal models of schizophrenia: Improving strategy to decipher and treat the disease?

Solenn Percelay , Caroline Lahogue , Jean-Marie Billard , Thomas Freret , Michel Boulouard et al.
Neuroscience and Biobehavioral Reviews, 2024, 157, ⟨10.1016/j.neubiorev.2023.105526⟩
Article dans une revue hal-04593829 v1
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5-HT6 Receptors Sex-Dependently Modulate Hippocampal Synaptic Activity through GABA Inhibition

Caroline Lahogue , Jean-Marie Billard , Thomas Freret , Valentine Bouet
Biomolecules, 2023, 13 (5), pp.751. ⟨10.3390/biom13050751⟩
Article dans une revue hal-04089829 v1
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A new 3-hit mouse model of schizophrenia built on genetic, early and late factors

Valentine Bouet , Solenn Percelay , Elise Leroux , Boubacar Diarra , Marianne Léger et al.
Schizophrenia Research, 2021, 228, pp.519-528. ⟨10.1016/j.schres.2020.11.043⟩
Article dans une revue hal-04212366 v1
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Serine Racemase Deletion Affects the Excitatory/Inhibitory Balance of the Hippocampal CA1 Network

Eva Ploux , Valentine Bouet , Inna Radzishevsky , Herman Wolosker , Thomas Freret et al.
International Journal of Molecular Sciences, 2020, 21 (24), pp.9447. ⟨10.3390/ijms21249447⟩
Article dans une revue hal-03072318 v1

Long-Term Music Exposure Prevents Age-Related Cognitive Deficits in Rats Independently of Hippocampal Neurogenesis

Lou Rizzolo , Marianne Leger , Sophie Corvaisier , Mathilde Groussard , Hervé Platel et al.
Cerebral Cortex, 2020, 31 (1), pp.620-634. ⟨10.1093/cercor/bhaa247⟩
Article dans une revue hal-03019700 v1
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Author Correction: Dual orexin receptor antagonist induces changes in core body temperature in rats after exercise

Tristan Martin , Yves Dauvilliers , Ouma-Chandrou Koumar , Valentine Bouet , Thomas Freret et al.
Scientific Reports, 2020, 10 (1), pp.6030. ⟨10.1038/s41598-020-62685-6⟩
Article dans une revue hal-03518966 v1
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Morphological and functional correlates of vestibular synaptic deafferentation and repair in a mouse model of acute-onset vertigo

Raphaelle Cassel , Pierrick Bordiga , Julie Carcaud , François Simon , Mathieu Beraneck et al.
Disease Models & Mechanisms, 2019, 12 (7), pp.dmm039115. ⟨10.1242/dmm.039115⟩
Article dans une revue hal-02352249 v1
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Olfactory Laterality Is Valence-Dependent in Mice

Christelle Jozet-Alves , Solenn Percelay , Valentine Bouet
Symmetry, 2019, 11 (9), pp.1129. ⟨10.3390/sym11091129⟩
Article dans une revue hal-02279643 v1
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Evaluation of the impact of S-adenosylmethionine-dependent methyltransferase inhibitor, 3-deazaneplanocin A, on tissue injury and cognitive function in mice

Eva Lhuissier , Juliette Aury-Landas , Valentine Bouët , Céline Bazille , Yohann Repesse et al.
Oncotarget, 2018, 9 (29), pp.20698 - 20708. ⟨10.18632/oncotarget.25062⟩
Article dans une revue hal-01796395 v1

Repeated dexamphetamine treatment alters the dopaminergic system and increases the phMRI response to methylphenidate

Anouk Schrantee , Jordi Tremoleda , Marzena Wylezinska-Arridge , Valentine Bouet , Peter Hesseling et al.
PLoS ONE, 2017, 12 (2), pp.e0172776. ⟨10.1371/journal.pone.0172776⟩
Article dans une revue hal-02135218 v1

Time-dependent impact of glutamatergic modulators on the promnesiant effect of 5-HT 6 R blockade on mice recognition memory

Rachel Asselot , Emmanuelle Simon-O'Brien , Sophie Lebourgeois , Gérald Nee , Virgile Delaunay et al.
Pharmacological Research, 2017, 118, pp.111-118. ⟨10.1016/j.phrs.2016.06.009⟩
Article dans une revue hal-02135223 v1

Classical music reduces acute stress of domestic horses

C. Neveux , M. Ferard , L. Dickel , Valentine Bouet , O. Petit et al.
Journal of Veterinary Behavior: Clinical Applications and Research, 2016, 15, pp.81. ⟨10.1016/J.JVEB.2016.08.019⟩
Article dans une revue hal-02404794 v1

Chronic activation of 5-HT4 receptors or blockade of 5-HT6 receptors improve memory performances

Anne Quiedeville , Michel Boulouard , Katia Hamidouche , Virginie da Silva Costa-Aze , Gerald Nee et al.
Behavioural Brain Research, 2015, 293, pp.10-17. ⟨10.1016/j.bbr.2015.07.020⟩
Article dans une revue hal-02043824 v1

Therapeutic Potential of 5-HT 6 Receptor Agonists

Delphine Karila , Thomas Freret , Valentine Bouet , Michel Boulouard , Patrick Dallemagne et al.
Journal of Medicinal Chemistry, 2015, 58 (20), pp.7901-7912. ⟨10.1021/acs.jmedchem.5b00179⟩
Article dans une revue hal-02043781 v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Cédric Lecoutey , Cédric Lecoutey , Florence Gaven , Patrizia Giannoni , Katia Hamidouche et al.
Journal of Medicinal Chemistry, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩
Article dans une revue hal-02043873 v1

Environmental Enrichment Duration Differentially Affects Behavior and Neuroplasticity in Adult Mice

Marianne Leger , Eleni Paizanis , Kwamivi Dzahini , Anne Quiedeville , Valentine Bouet et al.
Cerebral Cortex, 2015, 25 (11), pp.4048-4061. ⟨10.1093/cercor/bhu119⟩
Article dans une revue hal-02135292 v1
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Spatial memory deficit across aging: current insights of the role of 5-HT7 receptors

Gregory Beaudet , Valentine Bouet , Christelle Jozet-Alves , Pascale Schumann-Bard , Francois Dauphin et al.
Frontiers in Behavioral Neuroscience, 2015, 8, pp.448. ⟨10.3389/fnbeh.2014.00448⟩
Article dans une revue hal-01472654 v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey , Damien Hedou , Thomas Freret , Patrizia Giannoni , Florence Gaven et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Article dans une revue hal-01800439 v2

Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging

Véronique Paban , Jean-Marie Billard , Valentine Bouet , Thomas Freret , Michel Boulouard et al.
Brain Structure and Function, 2013, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩
Article dans une revue istex hal-02325134 v1

Object recognition test in mice

Marianne Leger , Anne Quiedeville , Valentine Bouet , Benoît Haelewyn , Michel Boulouard et al.
Nature Protocols, 2013, 8 (12), pp.2531-2537. ⟨10.1038/nprot.2013.155⟩
Article dans une revue hal-02135259 v1

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT(4) receptor activation (RS67333) on object recognition in mice.

Thomas Freret , Valentine Bouet , Anne Quiedeville , Gérald Nee , Patrick Dallemagne et al.
Behavioural Brain Research, 2012, 230 (1), pp.304-8. ⟨10.1016/j.bbr.2012.02.012⟩
Article dans une revue istex hal-00862757 v1

Genomic transcriptional profiling in LOU/C/Jall rats identifies genes for successful aging.

Véronique Paban , Jean-Marie Billard , Valentine Bouet , Thomas Freret , Michel Boulouard et al.
Brain Structure and Function, 2012, 218 (6), pp.1501-1512. ⟨10.1007/s00429-012-0472-8⟩
Article dans une revue istex hal-00862299 v1

Synergistic effect of acetylcholinesterase inhibition (donepezil) and 5-HT4 receptor activation (RS67333) on object recognition in mice.

Thomas Freret , Valentine Bouet , Anne Quiedeville , Gérald Nee , Patrick Dallemagne et al.
Behavioural Brain Research, 2012, 230 (1), pp.304-308. ⟨10.1016/j.bbr.2012.02.012⟩
Article dans une revue istex hal-00821461 v1

Age-dependent effects of chronic fluoxetine treatment on the serotonergic system one week following treatment.

Valentine Bouet , Anne Klomp , Thomas Freret , Marzena Wylezinska-Arridge , Jordi Lopez-Tremoleda et al.
Psychopharmacology, 2012, 221 (2), pp.329-39. ⟨10.1007/s00213-011-2580-1⟩
Article dans une revue istex hal-00862306 v1

Maternal hypertension during pregnancy modifies the response of the immature brain to hypoxia-ischemia: sequential MRI and behavioral investigations.

Annelise Letourneur , Thomas Freret , Simon Roussel , Michel Boulouard , Didier Divoux et al.
Experimental Neurology, 2012, 233 (1), pp.264-72. ⟨10.1016/j.expneurol.2011.10.014⟩
Article dans une revue istex hal-00862822 v1

Environmental enrichment improves recent but not remote memory in association with a modified brain metabolic activation profile in adult mice.

Marianne Leger , Valentine Bouet , Thomas Freret , Anne-Sophie Darmaillacq , Matthieu Dacher et al.
Behavioural Brain Research, 2012, 228 (1), pp.22-9. ⟨10.1016/j.bbr.2011.11.022⟩
Article dans une revue istex hal-00862779 v1

Comparison of the effects of erythropoietin and its carbamylated derivative on behaviour and hippocampal neurogenesis in mice.

Claire Leconte , Ebeline Bihel , François-Xavier Lepelletier , Valentine Bouët , Romaric Saulnier et al.
Neuropharmacology, 2011, 60 (2-3), pp.354-64. ⟨10.1016/j.neuropharm.2010.09.025⟩
Article dans une revue istex hal-00863054 v1

Effect of pre- versus post-weaning environmental disturbances on social behaviour in mice.

Valentine Bouet , Blandine Lecrux , Gwenaelle Tran , Thomas Freret
Neuroscience Letters, 2011, 488 (2), pp.221-4. ⟨10.1016/j.neulet.2010.11.033⟩
Article dans une revue istex hal-00862841 v1

On the importance of long-term functional assessment after stroke to improve translation from bench to bedside.

Thomas Freret , Pascale Schumann-Bard , Michel Boulouard , Valentine Bouet
Experimental and Translational Stroke Medicine, 2011, 3, pp.6. ⟨10.1186/2040-7378-3-6⟩
Article dans une revue hal-00862997 v1

Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals.

Valentine Bouet , Thomas Freret , Patrick Dutar , Jean-Marie Billard , Michel Boulouard
Mechanisms of Ageing and Development, 2011, 132 (5), pp.240-8. ⟨10.1016/j.mad.2011.04.006⟩
Article dans une revue istex hal-00862993 v1

Continuous enriched environment improves learning and memory in adult NMRI mice through theta burst-related-LTP independent mechanisms but is not efficient in advanced aged animals

Valentine Bouet , Thomas Freret , Patrick Dutar , Jean-Marie Billard , Michel Boulouard
Mechanisms of Ageing and Development, 2011, 132 (5), pp.240-248. ⟨10.1016/j.mad.2011.04.006⟩
Article dans une revue istex hal-02325196 v1
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The impact of erythropoietin on short-term changes in phosphorylation of brain protein kinases in a rat model of traumatic brain injury.

Samuel Valable , Gilles Francony , Pierre Bouzat , Marie-Cécile Fevre , Nouara Mahious et al.
Journal of Cerebral Blood Flow and Metabolism, 2010, 30 (2), pp.361-9. ⟨10.1038/jcbfm.2009.222⟩
Article dans une revue inserm-00517172 v1

Predicting sensorimotor and memory deficits after neonatal ischemic stroke with reperfusion in the rat.

Valentine Bouet , Thomas Freret , Steve Ankri , Madeleine Bezault , Sylvain Renolleau et al.
Behavioural Brain Research, 2010, 212 (1), pp.56-63. ⟨10.1016/j.bbr.2010.03.043⟩
Article dans une revue istex hal-00863083 v1

Behavioral deficits after distal focal cerebral ischemia in mice: Usefulness of adhesive removal test.

Thomas Freret , Valentine Bouet , Claire Leconte , Simon Roussel , Laurent Chazalviel et al.
Behavioral Neuroscience, 2009, 123 (1), pp.224-30. ⟨10.1037/a0014157⟩
Article dans une revue hal-00863264 v1

The effects of DHEA, 3beta-hydroxy-5alpha-androstane-6,17-dione, and 7-amino-DHEA analogues on short term and long term memory in the mouse.

Marc-Antoine Bazin , Laïla El Kihel , Michel Boulouard , Valentine Bouët , Sylvain Rault
Steroids, 2009, 74 (12), pp.931-7. ⟨10.1016/j.steroids.2009.06.010⟩
Article dans une revue istex hal-00863107 v1

The impact of erythropoietin on short-term changes in phosphorylation of brain protein kinases in a rat model of traumatic brain injury

Samuel Valable , Gilles Francony , Pierre Bouzat , Marie-Cécile Fevre , Nouara Mahious et al.
Journal of Cerebral Blood Flow and Metabolism, 2009, 30, pp.361-369. ⟨10.1038/jcbfm.2009.222⟩
Article dans une revue hal-00866969 v1

The adhesive removal test: a sensitive method to assess sensorimotor deficits in mice.

Valentine Bouet , Michel Boulouard , Jérôme Toutain , Didier Divoux , Myriam Bernaudin et al.
Nature Protocols, 2009, 4 (10), pp.1560-4. ⟨10.1038/nprot.2009.125⟩
Article dans une revue hal-00863258 v1

Intraluminal thread model of focal stroke in the non-human primate

Thomas Freret , Valentine Bouet , Jérôme Toutain , Romaric Saulnier , Palma Pro-Sistiaga et al.
Journal of Cerebral Blood Flow and Metabolism, 2008, 28 (4), pp.786-96. ⟨10.1038/sj.jcbfm.9600575⟩
Article dans une revue hal-00863332 v1

Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse.

Valentine Bouët , Thomas Freret , Jérôme Toutain , Didier Divoux , Michel Boulouard et al.
Experimental Neurology, 2007, 203 (2), pp.555-67. ⟨10.1016/j.expneurol.2006.09.006⟩
Article dans une revue istex hal-00178296 v1

Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse

Benoît Haelewyn , Thomas Freret , Emilie Pacary , Pascale Schumann-Bard , Michel Boulouard et al.
Behavioural Brain Research, 2007, 178, pp.235-243. ⟨10.1016/j.bbr.2006.12.023⟩
Article dans une revue istex hal-00867870 v1

Long-term evaluation of sensorimotor and mnesic behaviour following striatal NMDA-induced unilateral excitotoxic lesion in the mouse.

Benoît Haelewyn , Thomas Freret , Emilie Pacary , Pascale Schumann-Bard , Michel Boulouard et al.
Behavioural Brain Research, 2007, 178 (2), pp.235-43. ⟨10.1016/j.bbr.2006.12.023⟩
Article dans une revue istex hal-00178443 v1

Sensorimotor and cognitive deficits after transient middle cerebral artery occlusion in the mouse

Valentine Bouet , Thomas Freret , J. Toutain , Didier Divoux , Michel Boulouard et al.
Experimental Neurology, 2006, 203, pp.55-567. ⟨10.1016/j.expneurol.2006.09.006⟩
Article dans une revue istex hal-00867774 v1

Changes in rat soleus muscle phenotype consecutive no a growth in hypergravity followed by normogravity

F. Picquet , Valentine Bouet , L. Cochon , Michel Lacour , M. Falenpin
AJP - Regulatory, Integrative and Comparative Physiology, 2005, 289, pp.217-224
Article dans une revue hal-00095247 v1

Hypergravity from conception to adult stage: effects on contractile properties and skeletal muscle phenotype

C. Bozzo , L. Stevens , Valentine Bouët , V. Montel , F. Picquet et al.
Journal of Experimental Biology, 2004, 207, pp.2793-2802
Article dans une revue hal-00095288 v1

Kinematics of treadmill locomotion in rats conceived, born and reared in a hypergravity field (2g). Adaptation to 1 g

Valentine Bouet , Liliane Borel , Françoise Harlay , Yves Gahery , Michel Lacour
Behavioural Brain Research, 2004, 150(1-2), pp.207-216
Article dans une revue hal-00095298 v1

Behavioural changes induced by early and long-term gravito-inertial force modification in the rat

Valentine Bouët , Yves Gahéry , Michel Lacour
Behavioural Brain Research, 2003, 139, pp.97-104
Article dans une revue hal-00095319 v1

Contractile properties and myosin expression in rats born and reared in hypergravity.

F. Picquet , Valentine Bouët , Mh Canu , L. Stevens , Michel Lacour et al.
AJP - Regulatory, Integrative and Comparative Physiology, 2002, 282, pp.1687-1695
Article dans une revue hal-00095467 v1
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Short and long-term cognitive impairment in mice exposed to hypergravity depends on sex

Wullen Mathilde , Jean-Marie Billard , Thomas Freret , Valentine Bouet
Journée de l'école doctorale, May 2024, Caen, France
Poster de conférence hal-04669804 v1
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Investigating hippocampal synaptic plasticity in schizophrenia: A computational and experimental approach using MEA recordings

Sarah Hamdi Cherif , Candice Roux , Valentine Bouet , Jean-Marie Billard , Jérémie Gaidamour et al.
Bernstein Conference, Sep 2024, Frankfurt, Germany. 2024, ⟨10.12751/nncn.bc2024.244⟩
Poster de conférence hal-04835241 v1
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Treatment strategy targeting 5-HT6R in an innovative animal model of Schizophrenia

Caroline Lahogue , Michel Boulouard , François Menager , Thomas Freret , Jean-Marie Billard et al.
FENS 2024, Jun 2024, Vienne, Austria
Poster de conférence hal-04634813 v1
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Hippocampal functional adaptation to hypergravity exposure : new insights for cognitive alterations in astronauts

Wullen Mathilde , Valentine Bouet , Thomas Freret , Jean-Marie Billard
Groupe De Recherche interdisciplinaire Mémoire, Oct 2023, Carry-le-rouet, France
Poster de conférence hal-04669799 v1
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Sex-dependent 5-HT6Rs effects on hippocampal synaptic activity

Caroline Lahogue , Jean-Marie Billard , Thomas Freret , Valentine Bouet
NeuroFrance 2023 -, May 2023, Lyon, France.
Poster de conférence hal-04216532 v1
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Efficacy of a selective 5-HT6R antagonist in an innovative 2-hit mouse model of schizophrenia

Caroline Lahogue , Morgane Jobard , Jean-Marie Billard , Valentine Bouet
FENS, Jul 2022, Paris, France
Poster de conférence hal-04216519 v1
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Combining adverse factors to build a new 3-hit model of schizophrenia

Solenn Percelay , Valentine Bouët , Thomas Freret , Michel Boulouard
XXIIème journées de l'Ecole Doctorale normande de Biologie Intégrétive, Santé, Environnement, Mar 2019, Caen, France. , 2019
Poster de conférence hal-02135476 v1
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Mimicking schizophrenia symptoms in mice by combining factors: genetic, early environmental stress and late pharmacological conditioning

Valentine Bouët , Solenn Percelay , Nicole Turnbull , Thomas Freret , Michel Boulouard
NeuroFrance, May 2019, Marseille, France
Poster de conférence hal-02492831 v1
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New 3-hit model of schizophrenia: behavioral and electrophysiological investigations

Solenn Percelay , Valentine Bouet , Jean-Marie Billard , Thomas Freret , Michel Boulouard
23ème journée de LARC, Sep 2019, Nantes, France. ⟨10.4103/ipj.ipj_30_15⟩
Poster de conférence hal-02363078 v1
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New mouse model of schizophrenia: "3 hits" model, genetic and environmental factors

Solenn Percelay , Valentine Bouët , Thomas Freret , Michel Boulouard
XXIème journées de l'Ecole Doctorale normande de Biologie Intégrative, Santé, Environnement, Mar 2018, Rouen, France. 2018
Poster de conférence hal-02135458 v1
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Schizophrenia: validity of a 3-hit mouse model

Solenn Percelay , Thomas Freret , Boubacar Diarra , Nicolas Delcroix , Elise Leroux et al.
11th Federation of European Neuroscience Societies Forum of Neuroscience, Jul 2018, Berlin, Germany. , 2018
Poster de conférence hal-02135529 v1

The role of serotonin 5-HT7 receptors in spatial navigation in the mouse

Gregory Beaudet , Christelle Jozet-Alves , Morgane Chrétien , Thomas Freret , Pascale Schumann-Bard et al.
18ème journée de l’Ecole doctorale EdnBISE, Mar 2015, Rouen, France
Poster de conférence hal-02436408 v1

La musique adoucit les mœurs…et diminue le stress

Claire Neveux , Marion Ferard , Ludovic Dickel , Valentine Bouet , Léa Lansade et al.
Colloque National de la SFECA, Apr 2015, Strasbourg, France. 2015, Colloque National de la SFECA
Poster de conférence hal-02743020 v1

5-HT7 receptors are strongly implicated in allocentric navigation strategy in mice

Gregory Beaudet , Christelle Jozet-Alves , Thomas Freret , Pascale Schumann-Bard , Valentine Bouet et al.
19ème Congrès de la Société Française de Pharmacologie et de Thérapeutique, Apr 2015, Caen, France
Poster de conférence hal-02436415 v1

La musique adoucit les moeurs... et diminue le stress

Claire Neveux , Marion Ferard , Ludovic Dickel , Valentine Bouët , Léa Lansade et al.
45ème Colloque Annuel de la SFECA, Apr 2015, Strasbourg, France.
Poster de conférence hal-02434067 v1
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Sex-related impairment of synaptic plasticity in the hippocampus of hypergravity-exposed mice: new insights for cognition in space

Wullen Mathilde , Thomas Freret , Valentine Bouet , Jean-Marie Billard
FENS Forum 2024, FENS, Jun 2024, Wien, Austria
Communication dans un congrès hal-04624901 v1

La musique classique réduit les manifestations de stress aigu chez le cheval domestique

Marion Ferard , Claire Neveux , Ludovic Dickel , Valentine Bouët , Odile Petit et al.
46ème Colloque Annuel de la SFECA, Société Française pour l'Etude du Comportement Animal; EA4259 GMPc, Mar 2016, Caen, France
Communication dans un congrès hal-02434158 v1