Vincent Aranzana-Climent

34
Documents
Affiliation actuelle
  • Pharmacologie des anti-infectieux et antibiorésistance [U 1070] (PHAR2 [Poitiers])
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Publications

Publications

A freely accessible, adaptable hollow-fiber setup to reproduce first-order absorption: illustration with linezolid cerebrospinal fluid pharmacokinetic data

Noémie Prébonnaud , Alexia Chauzy , Nicolas Grégoire , Claire Dahyot-Fizelier , Christophe Adier et al.
Microbiology Spectrum, 2025, ⟨10.1128/spectrum.00051-25⟩
Article dans une revue hal-05085650 v1
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Prediction of higher ceftazidime–avibactam concentrations in the human renal interstitium compared with unbound plasma using a minimal physiologically based pharmacokinetic model developed in rats and pigs through microdialysis

Maxime Vallée , Vincent Aranzana-Climent , Jérémy Moreau , Isabelle Lamarche , Théo Fontanier et al.
Antimicrobial Agents and Chemotherapy, 2025, 69 (3), pp.e0151824. ⟨10.1128/aac.01518-24⟩
Article dans une revue hal-04950970 v1

An integrative and translational PK/PD modelling approach to explore the combined effect of polymyxin B and minocycline against <i>Klebsiella pneumoniae</i>

Chenyan Zhao , Sanne van den Berg , Zhigang Wang , Anna Olsson , Vincent Aranzana-Climent et al.
International Journal of Antimicrobial Agents, 2025, 65 (3), pp.107443. ⟨10.1016/j.ijantimicag.2025.107443⟩
Article dans une revue hal-05144878 v1

Optimizing antimicrobial susceptibility testing: cost and environmental benefits of MIC volume reduction

Jonathan Clarhaut , Jeremy Moreau , Tom Collet , Emma Babiard , Vincent Aranzana-Climent et al.
Antimicrobial Agents and Chemotherapy, 2025, ⟨10.1128/aac.00704-25⟩
Article dans une revue hal-05321893 v1

Tissue distribution of Ceftazidime-Avibactam in kidney tissue in healthy rats and pigs using a microdialysis technique

Maxime Vallée , Jérémy Moreau , Isabelle Lamarche , Céline Barc , Nathalie Kasal-Hoc et al.
European Urology, 2024, Abstracts EAU24 - 39th Annual EAU Congress, 85 (Supplément 1), pp.S127-S128
Article dans une revue hal-04913348 v1

Étude de la distribution tissulaire du ceftazidime-avibactam dans le parenchyme rénal de rats et de porcs par technique de micro-dialyse

Maxime Vallée , Jérémy Moreau , Théo Fontanier , Isabelle Lamarche , Hélène Mirfendereski et al.
Progrès en Urologie - FMC, 2024, 34 (7), pp.S127-S128. ⟨10.1016/j.fpurol.2024.07.179⟩
Article dans une revue hal-04906357 v1

Distribution tissulaire du Meropeneme-Vaborbactam dans le rein et la prostate chez le rat et le cochon sain par micro-dialyse

Théo Fontanier , Isabelle Lamarche , Céline Barc , Vincent Aranzana-Climent , Hélène Mirfendereski et al.
Progrès en Urologie - FMC, 2024, 34 (7), pp.S134-S135. ⟨10.1016/j.fpurol.2024.07.188⟩
Article dans une revue hal-04906538 v1
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Integration of individual preclinical and clinical anti‐infective PKPD data to predict clinical study outcomes

Vincent Aranzana-Climent , Wisse van Os , Amir Nutman , Jonathan Lellouche , Yael Dishon-Benattar et al.
Clinical and Translational Science., 2024, 17 (7), pp.e13870. ⟨10.1111/cts.13870⟩
Article dans une revue hal-04645902 v1

Model-informed drug development for antimicrobials: translational pharmacokinetic-pharmacodynamic modelling of apramycin to facilitate prediction of efficacious dose in complicated urinary tract infections

Irene Hernández-Lozano , Vincent Aranzana-Climent , Sha Cao , Carina Matias , Jon Ulf Hansen et al.
Journal of Antimicrobial Chemotherapy, 2024, Online ahead of print. ⟨10.1093/jac/dkae409⟩
Article dans une revue hal-04800350 v1

Characterization of Pseudomonas aeruginosa resistance to ceftolozane-tazobactam due to ampC and/or ampD mutations observed during treatment using semi-mechanistic PKPD modeling

Luc Deroche , Vincent Aranzana-Climent , Albane Rozenholc , Laure Prouvensier , Léa Darnaud et al.
Antimicrobial Agents and Chemotherapy, 2023, ⟨10.1128/aac.00480-23⟩
Article dans une revue hal-04227340 v1
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Pharmacokinetic and pharmacodynamic properties of polymyxin B in Escherichia coli and Klebsiella pneumoniae murine infection models

Aart van der Meijden , Vincent Aranzana-Climent , Heleen van der Spek , Brenda de Winter , William Couet et al.
Journal of Antimicrobial Chemotherapy, 2023, 78 (3), pp.832-839. ⟨10.1093/jac/dkad022⟩
Article dans une revue hal-04088061 v1

Translational in vitro and in vivo PKPD modelling for apramycin against Gram-negative lung pathogens to facilitate prediction of human efficacious dose in pneumonia

Vincent Aranzana-Climent , Diarmaid Hughes , Sha Cao , Magdalena Tomczak , Malgorzata Urbas et al.
Clinical Microbiology and Infection, 2022, 28 (10), pp.1367-1374. ⟨10.1016/j.cmi.2022.05.003⟩
Article dans une revue hal-04389011 v1
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A New Pharmacokinetic-Pharmacodynamic Model To Characterize the Inoculum Effect of Acinetobacter baumannii on Polymyxin B In Vitro

Grace Akrong , Alexia Chauzy , Vincent Aranzana-Climent , Mathilde Lacroix , Luc Deroche et al.
Antimicrobial Agents and Chemotherapy, 2022, 66 (1), pp.e0178921. ⟨10.1128/AAC.01789-21⟩
Article dans une revue hal-03615758 v1
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PKPD Modeling of the Inoculum Effect of Acinetobacter baumannii on Polymyxin B in vivo

Alexia Chauzy , Grace Akrong , Vincent Aranzana-Climent , Jérémy Moreau , Laure Prouvensier et al.
Frontiers in Pharmacology, 2022, 13, pp.842921. ⟨10.3389/fphar.2022.842921⟩
Article dans une revue hal-03615739 v1

Pharmacokinetic/pharmacodynamic models for time courses of antibiotic effects

Iris Minichmayr , Vincent Aranzana-Climent , Lena Friberg
International Journal of Antimicrobial Agents, 2022, 60 (3), pp.106616. ⟨10.1016/j.ijantimicag.2022.106616⟩
Article dans une revue hal-04389002 v1
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A Minimal Physiologically Based Pharmacokinetic Model to Characterize CNS Distribution of Metronidazole in Neuro Care ICU Patients

Alexia Chauzy , Salim Bouchène , Vincent Aranzana-Climent , Jonathan Clarhaut , Christophe Adier et al.
Antibiotics, 2022, 11 (10), pp.1293. ⟨10.3390/antibiotics11101293⟩
Article dans une revue hal-03906712 v1

Expert workshop summary: Advancing toward a standardized murine model to evaluate treatments for antimicrobial resistance lung infections

Rakel Arrazuria , Bernhard Kerscher , Karen Huber , Jennifer Hoover , Carina Vingsbo Lundberg et al.
Frontiers in Microbiology, 2022, 13, ⟨10.3389/fmicb.2022.988725⟩
Article dans une revue hal-04388986 v1

Variability of murine bacterial pneumonia models used to evaluate antimicrobial agents

Rakel Arrazuria , Bernhard Kerscher , Karen Huber , Jennifer Hoover , Carina Vingsbo Lundberg et al.
Frontiers in Microbiology, 2022, 13, ⟨10.3389/fmicb.2022.988728⟩
Article dans une revue hal-04388991 v1

Efficacy of EBL-1003 (apramycin) against Acinetobacter baumannii lung infections in mice

Katja Becker , Vincent Aranzana-Climent , Sha Cao , Anna Nilsson , Reza Shariatgorji et al.
Clinical Microbiology and Infection, 2021, 27 (9), pp.1315-1321. ⟨10.1016/j.cmi.2020.12.004⟩
Article dans une revue hal-04389019 v1
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Semi-mechanistic PK-PD modelling of combined polymyxin B and minocycline against a polymyxin-resistant strain of Acinetobacter baumannii

Vincent Aranzana-Climent , Julien Buyck , Younes Smani , Jerónimo Pachón-Diaz , Sandrine Marchand et al.
Clinical Microbiology and Infection, 2020, ⟨10.1016/j.cmi.2020.01.017⟩
Article dans une revue hal-02482129 v1

Preclinical Pharmacokinetic and Pharmacodynamic Data To Support Cefoxitin Nebulization for the Treatment of Mycobacterium abscessus

Shachi Mehta , Vincent Aranzana-Climent , Blandine Rammaert , Nicolas Grégoire , Sandrine Marchand et al.
Antimicrobial Agents and Chemotherapy, 2019, 63 (7), ⟨10.1128/AAC.02651-18⟩
Article dans une revue hal-02477844 v1
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Clinical Pharmacokinetics and Pharmacodynamics of Colistin

Nicolas Grégoire , Vincent Aranzana-Climent , Sophie Magréault , Sandrine Marchand , William Couet
Clinical Pharmacokinetics, 2017, Epub ahead of print. ⟨10.1007/s40262-017-0561-1⟩
Article dans une revue inserm-01528483 v1

A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations

Yumi Yamamoto , Pyry Välitalo , Dirk-Jan van den Berg , Robin Hartman , Willem van den Brink et al.
Pharmaceutical Research, 2017, 34 (2), pp.333-351. ⟨10.1007/s11095-016-2065-3⟩
Article dans une revue hal-02472510 v1
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Simulation-based prediction of pharmacokinetic/pharmacodynamic (PK/PD) index for linezolid to treat cerebral infections in critically ill patients

Michael Burtin , Noémie Prébonnaud , Sandrine Marchand , Nicolas Grégoire , Claire Dahyot-Fizelier et al.
33rd PAGE meeting, Jun 2025, Thessalokini, Greece
Poster de conférence hal-05240779 v1
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Tissue distribution of Ceftazidime-Avibactam in kidney tissue in healthy rats and pigs using a microdialysis technique

Maxime Vallée , Céline Barc , Jérémy Moreau , Nathalie Kasal-Hoc , Isabelle Lamarche et al.
34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2024, Barcelona, Spain
Poster de conférence hal-04571042 v1

Tissue distribution of Ceftazidime-Avibactam in kidney tissue in healthy rats and pigs using a microdialysis technique

Maxime Vallée , Jérémy Moreau , Isabelle Lamarche , Céline Barc , Nathalie Kasal-Hoc et al.
39e Congrès de l'Association européenne d'urologie (EAU24), Apr 2024, Paris, France. , European Urology, 85 (Supplément 1), pp.S127-S128, Abstracts EAU24 - 39th Annual EAU Congress. ⟨10.1016/S0302-2838(24)00177-5⟩
Poster de conférence hal-04906706 v1
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Synergistic interaction between antifungal agents against Candida guilliermondii using pharmacodynamics-modelling approach

Adrien Baillod , Vincent Aranzana-Climent , Kevin Point , Sandrine Marchand , Kévin Brunet
34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2024, Barcelona, Spain
Poster de conférence hal-04571002 v1
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Development and validation of a PBPK model of gepotidacin in rats to predict exposure in human prostate

Vincent Aranzana-Climent , Valentin Al Jalali , Hwa-Ping Feng , Karen O'Dwyer , William Couet et al.
34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2024, Barcelona, Spain
Poster de conférence hal-04571063 v1
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Spotting method as a high throughput alternative to the conventional spread plating method

Vincent Aranzana-Climent , Laure Prouvensier , Tom Collet , Sandrine Marchand , Nicolas Grégoire et al.
34th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID), Apr 2024, Barcelona, Spain
Poster de conférence hal-04575530 v1