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Vincent Paillé

72
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Presentation

Neuroscience researcher at INRAE working on : 1\) Impact of an unbalanced perinatal diet on the development of circuits controlling food intake (reward and homeostatic circuits). What is the role of the gut-brain axis? 2\) What is the role of CCKergic signaling in cortico-striatal plasticity ? 3\) Electrophysiological study of the gut-brain axis (ENS, microbiota, vagus nerve...)
Chercheur en Neuroscience à l’INRAE travaillant sur : 1\) Impact d’une alimentation périnatale déséquilibrée sur le développement des circuits contrôlant la prise alimentaire (circuits de la récompense et homéostatique). Quel est le rôle de l’axe intestin cerveau? 2\) Etude du rôle de la signalisation CCKergique dans la plasticité cortico-striatale. 3\) Etude électrophysiologique de l’axe intestin-cerveau (SNE, microbiote, nerf vague…)

Publications

Separate gut-brain circuits for fat and sugar reinforcement combine to promote overeating

Molly Mcdougle , Alan de Araujo , Arashdeep Singh , Mingxin Yang , Isadora Braga
Cell Metabolism, 2024, 36 (2), pp.393-407.e7. ⟨10.1016/j.cmet.2023.12.014⟩
Journal articles hal-04634266v1
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The regulation of enteric neuron connectivity by semaphorin 5A is affected by the autism-associated S956G missense mutation

Morgane E Le Dréan , Catherine Le Berre-Scoul , Vincent Paillé , Martial Caillaud , Thibauld Oullier
iScience, 2024, 27 (5), pp.109638. ⟨10.1016/j.isci.2024.109638⟩
Journal articles hal-04666939v1

Comparison of commercially available antibodies for the detection of phosphorylated alpha‐synuclein in primary culture of ENS

Simon Lassozé , Adrien Guilhem de Lataillade , Thibauld Oullier , Michel Neunslist , Laurène Leclair‐visonneau
Neurogastroenterology & Motility, 2022, ⟨10.1111/nmo.14354⟩
Journal articles hal-03635092v1
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Synthetic alkyl-ether-lipid promotes TRPV2 channel trafficking trough PI3K/Akt-girdin axis in cancer cells and increases mammary tumour volume

Maxime Guéguinou , Romain Felix , Séverine Marionneau-Lambot , Thibauld Oullier , Aubin Penna
Cell Calcium, 2021, 97, pp.102435. ⟨10.1016/j.ceca.2021.102435⟩
Journal articles hal-03278876v1
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The ephrin receptor EphB2 regulates the connectivity and activity of enteric neurons

Raphael Bodin , Vincent Paillé , Thibauld Oullier , Tony Durand , Philippe Aubert
Journal of Biological Chemistry, 2021, 297 (5), pp.1-14. ⟨10.1016/j.jbc.2021.101300⟩
Journal articles hal-04329510v1

Maternal exposure to a mixture of prebiotics fosters colitis development in offspring mice

Amélie Le , Amandine Selle , Philippe Aubert , Carole Brosseau , Emilie Durieu
Neurogastroenterology & Motility, 2020, 32 (1), pp.Meeting Abstract: 199
Journal articles hal-03269578v1
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Maternal Protein Restriction in Rats Alters the Expression of Genes Involved in Mitochondrial Metabolism and Epitranscriptomics in Fetal Hypothalamus

Morgane Frapin , Simon Guignard , Dimitri Meistermann , Isabelle Grit , Valentine S. Moullé
Nutrients, 2020, 12 (5), pp.1464. ⟨10.3390/nu12051464⟩
Journal articles inserm-02626031v1
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Moderate High Caloric Maternal Diet Impacts Dam Breast Milk Metabotype and Offspring Lipidome in a Sex-Specific Manner

Marie-Cécile Alexandre-Gouabau , Agnès David-Sochard , Anne-Lise Royer , Patricia Parnet , Vincent Paillé
International Journal of Molecular Sciences, 2020, 21 (15), pp.5428. ⟨10.3390/ijms21155428⟩
Journal articles hal-04667645v1
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Combined chemotherapy and allogeneic human Vγ9Vδ2 T lymphocyte-immunotherapies efficiently control the development of human epithelial ovarian cancer cells in vivo

Noémie Joalland , Laura Lafrance , Thibauld Oullier , Severine Marionneau-Lambot , Delphine Loussouarn
OncoImmunology, 2019, 8 (11), pp.e1649971. ⟨10.1080/2162402X.2019.1649971⟩
Journal articles inserm-02437297v1

Protein expression in submandibular glands of young rats is modified by a high-fat/high-sugar maternal diet

Martine Morzel , Hélène Brignot , Franck Menetrier , Géraldine Lucchi , Vincent Paille
Archives of Oral Biology, 2018, 96, pp.87-95. ⟨10.1016/j.archoralbio.2018.08.021⟩
Journal articles hal-02629327v1
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Perinatal Western Diet Consumption Leads to Profound Plasticity and GABAergic Phenotype Changes within Hypothalamus and Reward Pathway from Birth to Sexual Maturity in Rat

Julie Paradis , Pierre Boureau , Thomas Moyon , Sophie Nicklaus , Patricia Parnet
Frontiers in Endocrinology, 2017, 8, pp.216. ⟨10.3389/fendo.2017.00216⟩
Journal articles hal-01713096v1

Developmental control of spike-timing-dependent plasticity by tonic GABAergic signaling in striatum

Silvana Valtcheva , Vincent Paille , Yulia Dembitskaya , Sylvie Perez , Giuseppe Gangarossa
Neuropharmacology, 2017, 121, pp.261-277. ⟨10.1016/j.neuropharm.2017.04.012⟩
Journal articles hal-02407266v1
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The sensory and nutritional experience of parents guide offsprings' feeding behavior

Patricia Parnet , Vincent Paillé , Francisco Bolaños-Jiménez , Bertrand Kaeffer , Benoist Schaal
Médecine/Sciences, 2016, 32 (1), pp.85 - 92. ⟨10.1051/medsci/20163201014⟩
Journal articles hal-01400554v1

SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer

Emeline Bon , Virginie Driffort , Frédéric Gradek , Carlos Martinez-Caceres , Monique Anchelin
Nature Communications, 2016, 7 (1), ⟨10.1038/ncomms13648⟩
Journal articles hal-03471169v1
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Endocannabinoids mediate bidirectional striatal spike-timing dependent plasticity

Yihui Cui , Vincent Paille , Hao Xu , Stéphane Genet , Bruno Delord
The Journal of Physiology, 2015, 593 (13), pp.2833-2849. ⟨10.1113/JP270324⟩
Journal articles hal-01141205v1

Mycobacterial toxin induces analgesia in buruli ulcer by targeting the angiotensin pathways.

Estelle Marion , Ok-Ryul Song , Thierry Christophe , Jérémie Babonneau , Denis Fenistein
Cell, 2014, 157 (7), pp.1565-76. ⟨10.1016/j.cell.2014.04.040⟩
Journal articles hal-01117565v1
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PRIMA-1Met induces myeloma cell death independent of p53 by impairing the GSH/ROS balance

Benoît Tessoulin , Géraldine Descamps , Philippe Moreau , Sophie Maïga , Laurence Lodé
Blood, 2014, 124 (10), pp.1626 - 1636. ⟨10.1182/blood-2014-01-548800⟩
Journal articles inserm-03290437v1
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Ranolazine inhibits NaV1.5-mediated breast cancer cell invasiveness and lung colonization

Virginie Driffort , Ludovic Gillet , Emeline Bon , Séverine Marionneau-Lambot , Thibauld Oullier
Molecular Cancer, 2014, 13 (1), ⟨10.1186/1476-4598-13-264⟩
Journal articles hal-01822217v1

GABAergic Circuits Control Spike-Timing-Dependent Plasticity

V. Paille , E. Fino , K. Du , T. Morera-Herreras , S. Perez
Journal of Neuroscience, 2013, 33 (22), pp.9353-9363. ⟨10.1523/JNEUROSCI.5796-12.2013⟩
Journal articles hal-02407275v1

GABAergic Circuits Control Spike-Timing-Dependent Plasticity

V. Paille , E. Fino , K. Du , T. Morera-Herreras , S. Perez
Journal of Neuroscience, 2013, 33 (22), pp.9353-9363. ⟨10.1523/JNEUROSCI.5796-12.2013⟩
Journal articles hal-02876716v1

Pivotal Role of the Lipid Raft SK3-Orai1 Complex in Human Cancer Cell Migration and Bone Metastases.

Aurélie Chantôme , Marie Potier-Cartereau , Lucie Clarysse , Gaëlle Fromont , Séverine Marionneau-Lambot
Cancer Research, 2013, epub ahead of print. ⟨10.1158/0008-5472.CAN-12-4572⟩
Journal articles inserm-00848873v1

Novel Tetrahydropyrido[1,2-a]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache
Journal of Medicinal Chemistry, 2012, 55, pp.9589-9606
Journal articles hal-00785213v1

Novel Tetrahydropyrido[1,2- a ]isoindolone Derivatives (Valmerins): Potent Cyclin-Dependent Kinase/Glycogen Synthase Kinase 3 Inhibitors with Antiproliferative Activities and Antitumor Effects in Human Tumor Xenografts

Rajâa Boulahjar , Aziz Ouach , Chiurato Matteo , Stéphane Bourg , Myriam Ravache
Journal of Medicinal Chemistry, 2012, 55 (22), pp.9589-9606. ⟨10.1021/jm3008536⟩
Journal articles hal-02904751v1

New alkyl-lipid blockers of SK3 channels reduce cancer-cell migration and occurrence of metastasis

Alban Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantôme , Michelle Pinault
Current Cancer Drug Targets, 2011, 11, pp.1111-1125
Journal articles inserm-00662356v1

New Alkyl-Lipid Blockers of SK3 Channels Reduce Cancer Cell Migration and Occurrence of Metastasis

Alain Girault , Jean-Pierre Haelters , Marie Potier-Cartereau , Aurélie Chantome , Michelle Pinault
Current Cancer Drug Targets, 2011, 11 (9), pp.1111 - 1125. ⟨10.2174/156800911798073069⟩
Journal articles hal-01577240v1

Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia

Barbara Picconi , Vincenza Bagetta , Veronica Ghiglieri , Vincent Paillé , Massimiliano Di Filippo
Brain - A Journal of Neurology , 2011, 134 (2), pp.375-387. ⟨10.1093/brain/awq342⟩
Journal articles hal-03426414v1

Distinct coincidence detectors govern the corticostriatal spike timing-dependent plasticity

Elodie Fino , Vincent Paille , Yihui Cui , Teresa Morera-Herreras , Jean-Michel Deniau
The Journal of Physiology, 2010, 588 (16), pp.3045-3062. ⟨10.1113/jphysiol.2010.188466⟩
Journal articles hal-02407307v1

Distinct Levels of Dopamine Denervation Differentially Alter Striatal Synaptic Plasticity and NMDA Receptor Subunit Composition

Vincent Paillé , B. Picconi , V. Bagetta , V. Ghiglieri , C. Sgobio
Journal of Neuroscience, 2010, 30 (42), pp.14182-14193. ⟨10.1523/JNEUROSCI.2149-10.2010⟩
Journal articles hal-03426416v1

Asymmetric spike-timing dependent plasticity of striatal nitric oxide-synthase interneurons

E. Fino , V. Paille , J.-M. Deniau , L. Venance
Neuroscience, 2009, 160 (4), pp.744-754. ⟨10.1016/j.neuroscience.2009.03.015⟩
Journal articles hal-02407612v1

Kinetics of Microglial Activation and Degeneration of Dopamine-Containing Neurons in a Rat Model of Parkinson Disease Induced by 6-Hydroxydopamine

Vincent Henry , Vincent Paillé , Faustine Lelan , Philippe Brachet , Philippe Damier
Journal of Neuropathology and Experimental Neurology, 2009, 68 (10), pp.1092-1102. ⟨10.1097/NEN.0b013e3181b767b4⟩
Journal articles hal-03426420v1

Epilepsy-induced abnormal striatal plasticity in Bassoon mutant mice

Veronica Ghiglieri , Barbara Picconi , Carmelo Sgobio , Vincenza Bagetta , Ilaria Barone
European Journal of Neuroscience, 2009, 29 (10), pp.1979-1993. ⟨10.1111/j.1460-9568.2009.06733.x⟩
Journal articles hal-03426422v1

l-DOPA dosage is critically involved in dyskinesia via loss of synaptic depotentiation

Barbara Picconi , Vincent Paillé , Veronica Ghiglieri , Vincenza Bagetta , Ilaria Barone
Neurobiology of Disease, 2008, 29 (2), pp.327-335. ⟨10.1016/j.nbd.2007.10.001⟩
Journal articles hal-03426423v1

Rat model of Parkinson's disease with bilateral motor abnormalities, reversible with levodopa, and dyskinesias

Vincent Paillé , Vincent Henry , Laurent Lescaudron , Philippe Brachet , Philippe Damier
Movement Disorders, 2007, 22 (4), pp.533-539. ⟨10.1002/mds.21308⟩
Journal articles hal-03426427v1

Role of nigral lesion in the genesis of dyskinesias in a rat model of Parkinsonʼs disease

Vincent Paillé , Philippe Brachet , Philippe Damier
NeuroReport, 2004, 15 (3), pp.561-564. ⟨10.1097/00001756-200403010-00035⟩
Journal articles hal-03426429v1

Lipopolysaccharide and TNFα regulate the expression of GDNF, neurturin and their receptors

Séverine Rémy , Philippe Naveilhan , Vincent Paillé , Philippe Brachet , Isabelle Neveu
NeuroReport, 2003, 14 (11), pp.1529-1534. ⟨10.1097/00001756-200308060-00026⟩
Journal articles hal-03426430v1

Le microbiote et cerveau

Vincent Paille
Café des Sciences, café du Commerce, Mar 2019, Nantes, France
Conference papers hal-02789049v1

Alimentation Périnatale et Santé

Vincent Paille
Congrès des Master Biologie Santé d’Angers, Université d'Angers (UA). FRA., Oct 2019, Angers, France
Conference papers hal-02789563v1

Balanced food intake after weaning reverses the inapropriate food preference in offspring of low-protein diet fed dams correlated with reward pathway modifications

Julie Paradis , Morgane Frapin , Anthony Pagniez , Patricia Parnet , Vincent Paille
23 rd Annual Meeting LARC-Neurosciences Network, LARC., Oct 2019, Nantes, France
Conference papers hal-02735629v1

Maternal nutrition and epitranscriptomics

Morgane Frapin , Dimitri Meistermann , Simon Guignard , Vincent Paille , Patricia Parnet
Abcam conference RNA in epigenetic and chromatin regulation, May 2019, Paris, France
Conference papers hal-02789029v1

Impact d’une alimentation périnatale déséquilibrée sur le développement des circuits de la récompense chez le rat

Vincent Paille
Assises du département AlimH, Oct 2019, La Colle sur Loup, France
Conference papers hal-02735198v1

Opto et chemogenetique pour les nuls

Vincent Paille
Congrès de l’IMAD, Jun 2019, Nantes, France
Conference papers hal-02736256v1

Impact d’une alimentation périnatale déséquilibrée sur le développement des circuits de la récompense chez le rat,

Julie Paradis , Pierre Boureau , Thomas Moyon , Patricia Parnet , Vincent Paille
Journées scientifiques Jeunes chercheurs de l’IMAD, Jun 2018, Nantes, France
Conference papers hal-02735768v1

Exemple d’un parcours professionnel pour devenir Chargé de Recherche à l’INRA

Vincent Paille
Forum professionnel des sciences de la vie, Mar 2017, Nantes, France
Conference papers hal-02788908v1

Evolution des préférences alimentaires chez le rongeur, du début de la vie jusqu’à l’âge adulte, suite à une alimentation périnatale déséquilibrée

Vincent Paille
Journées Francophones de Nutrition, Dec 2017, Nantes, France
Conference papers hal-02736255v1

Stress-mediated remodeling of gap junctional communication in the adrenal medullary tissue

Michel G Desarménien , Vincent Paille , Bertrand Toutain , Christian Legros , Nathalie C Guérineau
6th conference of the Mediterranean Neuroscience Society, 2017, St. julian's, Malta
Conference papers hal-02735203v1

Stress-induced remodeling of adrenal stimulus-secretion coupling: evidence for bidirectional adaptative mechanisms

Vincent Paille , Michel G Desarménien , Bertrand Toutain , Frédéric de Nardi , Christian Legros
19th International Symposium on Chromaffin Cell Biology, Aug 2017, Sheffield, United Kingdom
Conference papers hal-02736254v1

L'expression protéique dans les glandes salivaires est impactée par un régime maternel de type Western-Diet chez le rat

Hélène Brignot , Franck Ménétrier , Emma Gangloff , Vincent Paille , Patricia Parnet
Journées francophones de nutrition (JFN), Nov 2016, Montpellier, France. 1 p
Conference papers hal-01519343v1

C’est quoi le métier de chercheur ?

Vincent Paille
Congrès Jeunes Chercheurs, Apr 2015, Les Brouzils, France
Conference papers hal-02798946v1

Is perinatal butyrate intake, through maternal supplementation, able to prevent cognitive impairment due to intrauterine growth restriction in a rat model?

Vincent Paille , H. Boudin , Isabelle Grit , Christian Bonnet , Pierre de Coppet
Second colloque de la SF – DOHAD, 2015, Nantes, France
Conference papers hal-02742782v1

Consequences of a high sugar/high fat maternal diet on protein expression in young rat salivary glands

Martine Morzel , Hélène Brignot , Marie-Chantal Canivenc-Lavier , Vincent Paille , Patricia Parnet
1. Congress of Physiology and Integrative Biology (CPBI), May 2015, Strasbourg, France. 92 p
Conference papers hal-01249245v1

Quels sont les moteurs de la faim ?

Vincent Paille
Semaine du cerveau (Brain awareness week), Mar 2015, Faculté de Médecine Nantes, France
Conference papers hal-02799168v1

Development on the attraction towards sweet and/or fatty foods in children: integrated understanding of the role of early experience on behavioral, molecular, physiological and neural outcomes, impact on food intake and on weight status (SWEETLIPKID)

Sophie Nicklaus , Vincent Paille
Séminaire Résidentiel Métaprogramme DID-IT, Apr 2014, Paris, France
Conference papers hal-02796568v1
Image document

Endocannabinoids mediate spike-timing dependent potentiation and depression: a model-based experimental approach

Yihui Cui , Vincent Paille , Bruno Delord , Stéphane Genet , Elodie Fino
the Twenty Second Annual Computational Neuroscience Meeting: CNS*2013, Jul 2013, Paris, France. O1 (2 p.), ⟨10.1186/1471-2202-14-S1-O1⟩
Conference papers inserm-00842298v1

Cholecystokininergic signaling exerts major control on cortico-striatal synaptic plasticity

Chloe Guillaume , Patricia Parnet , Vincent Paillé
NeuroFrance 2021, May 2021, Strasbourg - à distance, France.
Conference poster hal-03271287v1

Consuming a balanced diet from weaning reverses the inappropriate food preferences in offspring of low protein-diet fed dams but modifies the glutamatergic and dopaminergic circuits in hypothalamus and reward pathway

Julie Paradis , Morgane Frapin , Anthony Pagniez , Pierre Boureau , Patricia Parnet
NeuroFrance, May 2019, Marseille, France. , 2019
Conference poster hal-02736189v1

Maternal malnutrition and hypothalamic development

Morgane Frapin , Dimitri Meistermann , Simon Guignard , Vincent Paille , Patricia Parnet
4. Congrès SF DOHAD, Nov 2018, Grenoble, France. 2018
Conference poster hal-02789056v1

Maternal malnutrition and hypothalamic development

Morgane Frapin , Dimitri Meistermann , Simon Guignard , Vincent Paille , Patricia Parnet
From epigenome towards epitranscriptome in cell fate choice, Oct 2018, Capri, Italy. 2018
Conference poster hal-02789054v1

Impact of an unbalanced diet on the acquisition of food preferences and the development of reward circuits in rat

Julie Paradis , Pierre Boureau , Anthony Pagniez , Sophie Nicklaus , Patricia Parnet
11th FENS forum, Jul 2018, Berlin, Germany. 2018
Conference poster hal-02736146v1

Is perinatal butyrate, through maternal supplementation, able to prevent cognitive impairment due to intrauterine growth restriction in a rat model ?

Vincent Paille , Hélène Boudin , Isabelle Grit , Christian Bonnet , Pierre de Coppet
11th FENS forum, Jul 2018, Berlin, Germany. 2018
Conference poster hal-02736395v1

Maternal Western Diet” feeding of rat dams leads to profound plasticity and GABAergic phenotype changes within reward pathway from birth to sexual maturity in the offspring

Vincent Paille , Julie Paradis , Pierre Boureau , Anthony Pagniez , Sophie Nicklaus
NeuroFrance, May 2017, Bordeaux, France. 2017
Conference poster hal-02736955v1

Consuming a balanced diet from weaning reverses the programming of food preferences in offspring of Western-Diet-fed rat dams

Patricia Parnet , Julie Paradis , Pierre Boureau , Anthony Pagniez , Sophie Nicklaus
LARC Neuroscience, Oct 2017, Lille, France. 2017
Conference poster hal-02737904v1

Perinatal Western Diet consumption leads to a profound change in plasticity and GABAergic phenotype within hypothalamus and reward pathway from birth to sexual maturity in rat

Vincent Paille , Pierre Boureau , Anthony Pagniez , Marie-Chantal Canivenc , Sophie Nicklaus
3rd SF-DOhAD, Dec 2016, Paris, France. 2016
Conference poster hal-02742968v1

Adaptive remodeling of stimulus-secretion coupling in the adrenal medulla of spontaneously hypertensive rats

Vincent Paille , Bertrand Toutain , Frédéric de Nardi , Daniel Henrion , Christian Legros
27th ion channel meeting, Sep 2016, Sète, France. 2016
Conference poster hal-02741390v1

Consequences of a high sugar/high fat maternal diet on protein expression in young rat submandibular glands

Martine Morzel , Géraldine Lucchi , Patrick Ducoroy , Hélène Brignot , Marie-Chantal Canivenc-Lavier
Congrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015), 2015, Ajaccio, Corse (France), France. , 2015
Conference poster hal-01580713v1

Adaptive functional remodeling of stimulus-secretion coupling in the adrenal medulla of spontaneously hypertensive rats

N.C. Guerineau , Vincent Paille , Benoit Toutain , F. de Nardi , C. Lefort
12ème colloque de la Société des Neurosciences, May 2015, Montpellier, France. 2015
Conference poster hal-02741763v1

Tonic and phasic GABAergic signaling differently control corticostriatal spike-timing-dependent plasticity along development

Giuseppe Gangarossa , Vincent Paille , S Valtcheva , E Fino , L Venance
12ème colloque de la Société des Neurosciences, May 2015, Montpellier, France. 2015
Conference poster hal-02740864v1

Impact of perinatal over-nutrition on the developing sweet/fatty taste and the ontogeny of brain reward pathway, from birth to sexual maturity in rat

Vincent Paille , Pierre Boureau , Marie-Chantal Canivenc , Sophie Nicklaus , Patricia Parnet
12ème colloque de la Société des Neurosciences, May 2015, Montpellier, France. 2015
Conference poster hal-02742184v1
Image document

Endocannabinoids mediate spike-timing dependent potentiation and depression: a model-based experimental approach

Yihui Cui , Vincent Paille , Bruno Delord , Stéphane Genet , Elodie Fino
Twenty Second Annual Computational Neuroscience Meeting : CNS 2013, Jul 2013, Paris, France. 14 (Suppl 1), O1 (1 p.), 2013
Conference poster hal-00842299v1