Yvan De Launoit

49
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Publications

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Targeting ATF6α Attenuates UVB ‐Induced Senescence and Improves Skin Homeostasis by Regulating IL8 Expression

Joëlle Giroud , Pauline Delvaux , Laura Carlier , Clémentine de Schutter , Nathalie Martin et al.
Aging Cell, 2025, 24 (6), pp.e70024. ⟨10.1111/acel.70024⟩
Article dans une revue hal-05103261 v1
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Cell Senescence and the DNA Single-Strand Break Damage Repair Pathway

Parvathy A Sarma , Corinne Abbadie , Yvan de Launoit , Fabrizio Cleri
DNA, 2024, 4 (4), pp.530-552. ⟨10.3390/dna4040036⟩
Article dans une revue (article de synthèse) hal-04828409 v1
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Tri des cellules sénescentes par cytométrie en flux

Élodie Rodzinski , Nathalie Martin , Raphael Rouget , Adrien Pioger , Vanessa Dehennaut et al.
Médecine/Sciences, 2024, 40 (3), pp.275-282. ⟨10.1051/medsci/2024011⟩
Article dans une revue hal-04774057 v1
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Tri des cellules sénescentes par cytométrie en flux

Élodie Rodzinski , Nathalie Martin , Raphael Rouget , Adrien Pioger , Vanessa Dehennaut et al.
Médecine/Sciences, 2024, 40 (3), pp.275-282. ⟨10.1051/medsci/2024011⟩
Article dans une revue hal-04518057 v1
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Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor

Anthony Turpin , Carine Delliaux , Pauline Parent , Hortense Chevalier , Carmen Escudero-Iriarte et al.
British Journal of Cancer, 2023, 129 (12), pp.1903-1914. ⟨10.1038/s41416-023-02449-x⟩
Article dans une revue hal-04774153 v1
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Fascin-1 expression is associated with neuroendocrine prostate cancer and directly suppressed by androgen receptor

Anthony Turpin , Carine Delliaux , Pauline Parent , Hortense Chevalier , Carmen Escudero-Iriarte et al.
British Journal of Cancer, 2023, ⟨10.1038/s41416-023-02449-x⟩
Article dans une revue hal-04308764 v1

Flow Cytometry-based Method for Efficient Sorting of Senescent Cells

Erwan Goy , Nathalie Martin , Claire Drullion , Laure Saas , Olivier Molendi-Coste et al.
Bio-protocol , 2023, 13 (7), ⟨10.21769/BioProtoc.4612⟩
Article dans une revue hal-04268798 v1
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Flow Cytometry-based Method for Efficient Sorting of Senescent Cells

Erwan Goy , Nathalie Martin , Claire Drullion , Laure Saas , Olivier Molendi-Coste et al.
Bio-protocol , 2023, 13 (7), pp.e4612. ⟨10.21769/BioProtoc.4612⟩
Article dans une revue hal-04774160 v1

Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer

Leslie Duplaquet , Martin Figeac , Frédéric Leprêtre , Charline Frandemiche , Céline Villenet et al.
Molecular Cancer Therapeutics, 2019, 18 (6), pp.1137-1148. ⟨10.1158/1535-7163.MCT-18-0582⟩
Article dans une revue hal-04540714 v1

Aberrant up-regulation of iNOS/NO system is correlated with an increased abundance of Foxp3+ cells and reduced effector/memory cell markers expression during colorectal cancer: immunomodulatory effects of cetuximab combined with chemotherapy

Sarra Benkhelifa , Hayet Rafa , Said Belhadef , Hayat Ait-Kaci , Oussama Medjeber et al.
Inflammopharmacology, 2019, 27 (4), pp.685-700. ⟨10.1007/s10787-019-00566-9⟩
Article dans une revue hal-02391591 v1
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ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

Mandy Dumortier , Franck Ladam , Isabelle Damour , Sophie Vacher , Ivan Bieche et al.
Breast Cancer Research, 2018, 20 (1), pp.73. ⟨10.1186/s13058-018-0992-0⟩
Article dans une revue hal-02391607 v1
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TMPRSS2:ERG gene fusion expression regulates bone markers and enhances the osteoblastic phenotype of prostate cancer bone metastases

Carine Delliaux , Tian Tian , Mathilde Bouchet , Anais Fradet , Nathalie Vanpouille et al.
Cancer Letters, 2018, 438, pp.32 - 43. ⟨10.1016/j.canlet.2018.08.027⟩
Article dans une revue hal-03060052 v1
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All-Trans Retinoic Acid Modulates TLR4/NF- κ B Signaling Pathway Targeting TNF- α and Nitric Oxide Synthase 2 Expression in Colonic Mucosa during Ulcerative Colitis and Colitis Associated Cancer

Hayet Rafa , Sarra Benkhelifa , Sonia Aityounes , Houria Saoula , Said Belhadef et al.
Mediators of Inflammation, 2017, 2017, pp.7353252. ⟨10.1155/2017/7353252⟩
Article dans une revue hal-02391613 v1
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TMPRSS2-ERG fusion promotes prostate cancer metastases in bone

Rachel Deplus , Carine Delliaux , Nathalie Marchand , Anne Flourens , Nathalie Vanpouille et al.
Oncotarget, 2017, 8 (7), pp.11827-11840. ⟨10.18632/oncotarget.14399⟩
Article dans une revue hal-02391621 v1

Effect of Nasopharyngeal Carcinoma-Derived Exosomes on Human Regulatory T Cells

Dhafer Mrizak , Nathalie Martin , Clément Barjon , Anne-Sophie Jimenez-Pailhes , Rami Mustapha et al.
JNCI: Journal of the National Cancer Institute, 2015, 107 (1), pp.363. ⟨10.1093/jnci/dju363⟩
Article dans une revue hal-02395739 v1
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TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity

Dimitra Gkika , Loic Lemonnier , George Shapovalov , Dmitri Gordienko , Céline Poux et al.
Journal of Cell Biology, 2015, 208 (1), pp.89-107. ⟨10.1083/jcb.201402076⟩
Article dans une revue hal-01111024 v1
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The obesity-associated transcription factor ETV5 modulates circulating glucocorticoids

Ruth Gutierrez-Aguilar , Abigail Thompson , Nathalie Marchand , Patrick Dumont , Stephen C. Woods et al.
Physiology & behavior, 2015, 150, pp.38 - 42. ⟨10.1016/j.physbeh.2015.03.027⟩
Article dans une revue hal-03059809 v1
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PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells

Zoulika Kherrouche , Didier Monté , Elisabeth Werkmeister , Luc Stoven , Yvan de Launoit et al.
Molecular Oncology, 2015, 9 (9), pp.1852 - 1867. ⟨10.1016/j.molonc.2015.07.001⟩
Article dans une revue hal-03059808 v1

PEA3 transcription factors are downstream effectors of Met signaling involved in migration and invasiveness of Met-addicted tumor cells

Zoulika Kherrouche , Didier Monte , Elisabeth Werkmeister , Luc Stoven , Yvan de Launoit et al.
Molecular Oncology, 2015, 9 (9), pp.1852-1867. ⟨10.1016/j.molonc.2015.07.001⟩
Article dans une revue hal-02392146 v1

TRP channel–associated factors are a novel protein family that regulates TRPM8 trafficking and activity

Dimitra Gkika , Loic Lemonnier , George Shapovalov , Dmitri Gordienko , Céline Poux et al.
Journal of Cell Biology, 2015, 208 (1), pp.89-107. ⟨10.1083/jcb.201402076⟩
Article dans une revue hal-04321398 v1
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Regulation of DNA Methylation Patterns by CK2-Mediated Phosphorylation of Dnmt3a

Rachel Deplus , Loïc Blanchon , Arumugam Rajavelu , Abdelhalim Boukaba , Matthieu Defrance et al.
Cell Reports, 2014, 8 (3), pp.743 - 753. ⟨10.1016/j.celrep.2014.06.048⟩
Article dans une revue hal-01918737 v1

Epstein-Barr virus infection induces an increase of T regulatory type 1 cells in Hodgkin lymphoma patients

Olivier Moralès , Dhafer Mrizak , Violaine François , Rami Mustapha , Céline Miroux et al.
British Journal of Haematology, 2014, 166 (6), pp.875-890. ⟨10.1111/bjh.12980⟩
Article dans une revue hal-02395755 v1
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Overexpression of Regulatory T Cells Type 1 (Tr1) Specific Markers in a Patient with HCV-Induced Hepatocellular Carcinoma

Laurissa Ouaguia , Olivier Morales , Dhafer Mrizak , Khaldoun Ghazal , Emmanuel Boleslawski et al.
International Scholarly Research Notices, 2013, 2013, pp.928485. ⟨10.1155/2013/928485⟩
Article dans une revue hal-03059986 v1

Loss of a Negative Feedback Loop Involving Pea3 and Cyclin D2 Is Required for Pea3-Induced Migration in Transformed Mammary Epithelial Cells

Franck Ladam , Isabelle Damour , Patrick Dumont , Zoulika Kherrouche , Yvan de Launoit et al.
Molecular Cancer Research, 2013, 11 (11), pp.1412-1424. ⟨10.1158/1541-7786.MCR-13-0229⟩
Article dans une revue hal-02395816 v1

IL-23/IL-17A Axis Correlates with the Nitric Oxide Pathway in Inflammatory Bowel Disease: Immunomodulatory Effect of Retinoic Acid

Hayet Rafa , Houria Saoula , Mourad Belkhelfa , Oussama Medjeber , Imene Soufli et al.
Journal of Interferon and Cytokine Research, 2013, 33 (7), pp.355-368. ⟨10.1089/jir.2012.0063⟩
Article dans une revue hal-02395835 v1
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The Mediator complex subunit MED25 is targeted by the N-terminal transactivation domain of the PEA3 group members

Alexis Verger , Jean-Luc Baert , Kathye Verreman , Frédérique Dewitte , Elisabeth Ferreira et al.
Nucleic Acids Research, 2013, 41 (9), pp.4847-4859. ⟨10.1093/nar/gkt199⟩
Article dans une revue hal-02111611 v1

PLA2R1 kills cancer cells by inducing mitochondrial stress

Arnaud Augert , David Vindrieux , Christophe Girard , Benjamin Le Calvé , Baptiste Gras et al.
Free Radical Biology and Medicine, 2013, 65, pp.969-977. ⟨10.1016/j.freeradbiomed.2013.08.177⟩
Article dans une revue istex hal-02395811 v1

PLA2R1 Mediates Tumor Suppression by Activating JAK2

David Vindrieux , Arnaud Augert , Christophe Girard , Delphine Gitenay , Helene Lallet-Daher et al.
Cancer Research, 2013, 73 (20), pp.6334-6345. ⟨10.1158/0008-5472.CAN-13-0318⟩
Article dans une revue hal-02395807 v1
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Identification of novel TMPRSS2:ERG mechanisms in prostate cancer metastasis: involvement of MMP9 and PLXNA2

Anthony Turpin , Carine Delliaux , Pauline Parent , Hortense Chevalier , Carmen Escudero-Iriarte et al.
Oncogene, 2013, 33, pp.2204 - 2214. ⟨10.1038/onc.2013.176⟩
Article dans une revue hal-03059981 v1

Corticosteroids Do Not Reverse the Inhibitory Effect of Cyclosporine on Regulatory T-Cell Activity in Contrast to Mycophenolate Mofetil

C. Miroux , O. Morales , L. Ouaguia , L. Aoudjehane , E. Boleslawski et al.
Transplantation Proceedings, 2012, 44 (9), pp.2834-2839. ⟨10.1016/j.transproceed.2012.09.091⟩
Article dans une revue istex hal-02395841 v1

EBV Latency II-derived Peptides Induce A Specific CD4+ Cytotoxic T-cell Activity and Not A CD4+ Regulatory T-cell Response

Olivier Moralès , Stéphane Depil , Dhafer Mrizak , Nathalie Martin , Papa Alioune Ndour et al.
Journal of Immunotherapy, 2012, 35 (3), pp.254-266. ⟨10.1097/CJI.0b013e31824d72c5⟩
Article dans une revue hal-03059998 v1

Altered Expression of the Poly(ADP-Ribosyl)ation Enzymes in Uveal Melanoma and Regulation of PARG Gene Expression by the Transcription Factor ERM

Vanessa Molloy-Simard , Jean-François St-Laurent , François Vigneault , Manon Gaudreault , Natasha Dargis et al.
Investigative Ophthalmology & Visual Science, 2012, 53 (10), pp.6219. ⟨10.1167/iovs.11-8853⟩
Article dans une revue hal-03059995 v1
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Anti-apoptotic Role of Caspase-cleaved GAB1 Adaptor Protein in Hepatocyte Growth Factor/Scatter Factor-MET Receptor Protein Signaling

Arnaud Le Goff , Zongling Ji , Bérénice Leclercq , Roland Bourette , Alexandra Mougel et al.
Journal of Biological Chemistry, 2012, 287 (42), pp.35382-35396. ⟨10.1074/jbc.M112.409797⟩
Article dans une revue hal-03104091 v1
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Activation of a Helper and Not Regulatory Human CD4+ T Cell Response by Oncolytic H-1 Parvovirus

Olivier Moralès , Audrey Richard , Nathalie Martin , Dhafer Mrizak , Magalie Sénéchal et al.
PLoS ONE, 2012, 7 (2), pp.e32197. ⟨10.1371/journal.pone.0032197⟩
Article dans une revue hal-03059999 v1

In vitro effects of cyclosporine A and tacrolimus on regulatory T-cell proliferation and function.

Céline Miroux , Olivier Morales , Khaldoun Ghazal , Samia Ben Othman , Yvan de Launoit et al.
Transplantation, 2012, 94 (2), pp.123-31. ⟨10.1097/TP.0b013e3182590d8f⟩
Article dans une revue hal-00785885 v1
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The Coactivator Activator CoAA regulates PEA3 group member transcriptional activity

Kathye Verreman , Jean-Luc Baert , Alexis Verger , Hervé Drobecq , Elisabeth Ferreira et al.
Biochemical Journal, 2011, 439 (3), pp.469-477. ⟨10.1042/BJ20110728⟩
Article dans une revue hal-00633602 v1

NMR structure of the human Mediator MED25 ACID domain.

François Bontems , Alexis Verger , Frédérique Dewitte , Zoé Lens , Jean-Luc Baert et al.
Journal of Structural Biology, 2011, 174 (1), pp.245-51. ⟨10.1016/j.jsb.2010.10.011⟩
Article dans une revue istex hal-00589014 v1

Purification of SUMO-1 modified IκBα and complex formation with NF-κB

Zoé Lens , Frédérique Dewitte , Carine van Lint , Yvan de Launoit , Vincent Villeret et al.
Protein Expression and Purification, 2011, 80 (2), pp.211-216. ⟨10.1016/j.pep.2011.06.009⟩
Article dans une revue istex hal-03060002 v1

Autocrine Induction of Invasive and Metastatic Phenotypes by the MIF-CXCR4 Axis in Drug-Resistant Human Colon Cancer Cells

Anne-Frédérique Dessein , Laurence Stechly , Nicolas Jonckheere , Patrick Dumont , Didier Monté et al.
Cancer Research, 2010, 70 (11), pp.4644-4654. ⟨10.1158/0008-5472.CAN-09-3828⟩
Article dans une revue hal-02106460 v1

Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Karo Gosselin , Sébastien Martien , Albin Pourtier , Chantal Vercamer , Peter Ostoich et al.
Cancer Research, 2009, 69 (20), pp.7917-7925. ⟨10.1158/0008-5472.CAN-08-2510⟩
Article dans une revue hal-04277047 v1

Senescent keratinocytes die by autophagic programmed cell death.

Karo Gosselin , Emeric Deruy , Sébastien Martien , Chantal Vercamer , Fatima Bouali et al.
American Journal of Pathology, 2009, 174 (2), pp.423-35. ⟨10.2353/ajpath.2009.080332⟩
Article dans une revue hal-01260066 v1

Senescence-Associated Oxidative DNA Damage Promotes the Generation of Neoplastic Cells

Karo Gosselin , Sébastien Martien , Albin Dr Pourtier , Chantal Vercamer , Peter Ostoich et al.
Cancer Research, 2009, 69 (20), pp.7917-7925. ⟨10.1158/0008-5472.CAN-08-2510⟩
Article dans une revue hal-04488967 v1

Regulation of ploidy and senescence by the AMPK-related kinase NUAK1

Nicolas Humbert , Naveenan Navaratnam , Arnaud Augert , Marco da Costa , Sébastien Martien et al.
EMBO Journal, 2009, 29 (2), pp.376-386. ⟨10.1038/emboj.2009.342⟩
Article dans une revue hal-04277055 v1
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Synergistic activation of HIV-1 expression by deacetylase inhibitors and prostratin: implications for treatment of latent infection.

Sophie Reuse , Miriam Calao , Kabamba Kabeya , Allan Guiguen , Jean-Stéphane Gatot et al.
PLoS ONE, 2009, 4 (6), pp.e6093. ⟨10.1371/journal.pone.0006093⟩
Article dans une revue hal-00464770 v1

A Genetic Screen Identifies Topoisomerase 1 as a Regulator of Senescence

Nicolas Humbert , Sébastien Martien , Arnaud Augert , Marco da Costa , Sébastien Mauen et al.
Cancer Research, 2009, 69 (10), pp.4101-4106. ⟨10.1158/0008-5472.CAN-08-2864⟩
Article dans une revue hal-04277052 v1

The M-type receptor PLA2R regulates senescence through the p53 pathway.

Arnaud Augert , Christine Payré , Yvan de Launoit , Jesus Gil , Gérard Lambeau et al.
EMBO Reports, 2009, 10 (3), pp.271-7. ⟨10.1038/embor.2008.255⟩
Article dans une revue hal-00417702 v1

The Polycomb group protein EZH2 directly controls DNA methylation

Emmanuelle Viré , Carmen Brenner , Rachel Deplus , Loïc Blanchon , Mario Fraga et al.
Nature, 2006, 439 (7078), pp.871 - 874. ⟨10.1038/nature04431⟩
Article dans une revue istex hal-01918637 v1

Expression patterns of the Ets transcription factors from the PEA3 group during early stages of mouse development

Anne Chotteau-Lelievre , Pascal Dollé , Virginie Peronne , Laurent Coutte , Yvan de Launoit et al.
Mechanisms of Development, 2001, 108 (1-2), pp.191-195. ⟨10.1016/s0925-4773(01)00480-4⟩
Article dans une revue istex hal-04093242 v1