Aurélien LEBRUN

Ingénieur d'Etudes Hors Classe en RMN
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Documents
Affiliations actuelles
  • Plateforme d’Analyse et de Caractérisation Chimie Balard (Montpellier) (PAC Chimie Balard)
  • Laboratoire de Mesures Physiques, Université de Montpellier, Montpellier, France (LMP)
Contact

Présentation

  • Responsable d'un spectromètre RMN liquide 600 MHz équipé d'une cryoplateforme Prodigy avec cryosonde TCI.
  • Responsable de 2 spectromètres RMN liquide 400 MHz en libre accès.
  • Elucidation de structure de molécules organiques (substances naturelles, molécules issues de synthèse)

Domaines de recherche

Chimie

Compétences

RMN Elucidation structurale Substances naturelles Polymères molécules organiques

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Publications

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From slag to structure: Formation of novel iron oxalate crystals via Cyrene™-driven microwave chemistry

Limor Ben Neon , Aurelien Lebrun , Eddy Petit , Anne Julbe
Materialia, 2025, 41, pp.102443. ⟨10.1016/j.mtla.2025.102443⟩
Article dans une revue hal-05090848 v1
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Catalyst Selection for Body-Temperature Curable Polyurethane Networks from Poly(δ-Decalactone) and Lysine Diisocyanate

Marine Boursier , Aurelien Lebrun , Karine Parra , Sylvain Caillol , Julien Pinaud et al.
Polymers, 2025, 17, pp.2548. ⟨10.3390/polym17182548⟩
Article dans une revue hal-05271415 v1
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Third‐Generation CD73 Inhibitors Based on a 4,6‐Disubstituted‐2‐Thiopyridine Scaffold

Félix Grosjean , Maria Shaldaeva , Emeline Cros-Perrial , Céline Rodriguez , Rayane Ghoteimi et al.
ChemMedChem, 2025, ⟨10.1002/cmdc.202400662⟩
Article dans une revue hal-04879866 v1

Highly Flexible 3D Printed Gelatin-Pluronic F127 Scaffolds Seeded with Schwann Cells toward Nerve Regeneration

Sacha Barberat , Sakthivel Nagarajan , Michel Habib , Aurélien Lebrun , Naomi Nieswic et al.
ACS Biomaterials Science and Engineering, 2025, 11 (9), pp.5498-5511. ⟨10.1021/acsbiomaterials.5c00479⟩
Article dans une revue hal-05326766 v1
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Selective acylation of chitosan oligomers by several cyclic anhydrides as a 13C NMR quantification method

Paul Morandi , Steve Berthalon , Ghislain David , Aurelien Lebrun , Karine Parra et al.
Carbohydrate Polymer Technologies and Applications, 2024, 7, pp.100498. ⟨10.1016/j.carpta.2024.100498⟩
Article dans une revue hal-04990543 v1
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Star poly(lactide-co-glycolide) and poly(ε-caprolactone) polyurethanes with shape memory properties for biomedical applications

Gaëlle Savin , Iliass Kadmiri , Sylvain Caillol , Philippe Gonzalez , Aurélien Lebrun et al.
European Polymer Journal, 2024, 220, pp.113442. ⟨10.1016/j.eurpolymj.2024.113442⟩
Article dans une revue hal-04699510 v1
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One‐Pot Synthesis of Bioinspired Peptide‐Decorated Apatite Nanoparticles for Nanomedicine

Mathilde Guerin , Aurélien Lebrun , Liisa Kuhn , Thierry Azaïs , Guillaume P. Laurent et al.
Small, 2023, pp.2306358. ⟨10.1002/smll.202306358⟩
Article dans une revue hal-04295040 v1
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Paving the Way towards Sustainability of Polyurethanes: Synthesis and Properties of Terpene-Based Diisocyanate

Aliénor Delavarde , Sebastien Lemouzy , Aurélien Lebrun , Julien Pinaud , Sylvain Caillol
Molecules, 2023, 28 (20), pp.7133. ⟨10.3390/molecules28207133⟩
Article dans une revue hal-04246489 v1
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Fast and Cost‐Efficient 17 O‐Isotopic Labeling of Carboxylic Groups in Biomolecules: From Free Amino Acids to Peptide Chains

Jessica Špačková , Ieva Goldberga , Rishit Yadav , Guillaume Cazals , Aurélien Lebrun et al.
Chemistry - A European Journal, 2023, 29 (10), pp.e202203014. ⟨10.1002/chem.202203014⟩
Article dans une revue hal-04002744 v1

Mapping the N-Terminal Hexokinase-I Binding Site onto Voltage-Dependent Anion Channel-1 To Block Peripheral Nerve Demyelination

Benoit Gautier , Mélanie Forêt Jacquard , Sophie Guelfi , Scarlette Abbou , Elisa Gonzalez et al.
Journal of Medicinal Chemistry, 2022, 65 (17), pp.11633-11647. ⟨10.1021/acs.jmedchem.2c00411⟩
Article dans une revue hal-03987562 v1
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Fluorescent Dynamic Covalent Polymers for DNA Complexation and Templated Assembly

Clément Kotras , Maxime Leclercq , Maxime Roger , Camille Bouillon , Antonio Recupido et al.
Molecules, 2022, 27 (19), pp.6648. ⟨10.3390/molecules27196648⟩
Article dans une revue hal-03832051 v1
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Vegetable oil-based hybrid microparticles as a green and biocompatible system for subcutaneous drug delivery

Koceïla Doufène , Ilaria Basile , Aurélien Lebrun , Nelly Pirot , Aurélie Escande et al.
International Journal of Pharmaceutics, 2021, 592, pp.120070. ⟨10.1016/j.ijpharm.2020.120070⟩
Article dans une revue hal-03110144 v1
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Cost-efficient and user-friendly 17O/ 18O labeling procedures of fatty acids using mechanochemistry

Jessica Špačková , Charlyn Fabra , Guillaume Cazals , Marie Hubert-Roux , Isabelle Schmitz-Afonso et al.
Chemical Communications, 2021, 57 (55), pp.6812-6815. ⟨10.1039/D1CC02165F⟩
Article dans une revue hal-03322217 v1
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A Novel Sesquiterpene Lactone Xanthatin-13-(pyrrolidine-2-carboxylic acid) Isolated from Burdock Leaf Up-Regulates Cells’ Oxidative Stress Defense Pathway

Yanis A Idres , Didier Tousch , Guillaume Cazals , Aurélien Lebrun , Sarah Naceri et al.
Antioxidants , 2021, 10 (10), ⟨10.3390/antiox10101617⟩
Article dans une revue hal-03434251 v1
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Synthesis, Characterization and Encapsulation Properties of Rigid and Flexible Porphyrin Cages Assembled from N-Heterocyclic Carbene-Metal Bonds

Ludivine Poyac , Clémence Rose , Mohammad Wahiduzzaman , Aurélien Lebrun , Guillaume Cazals et al.
Inorganic Chemistry, 2021, 60 (24), pp.19009-19021. ⟨10.1021/acs.inorgchem.1c02868⟩
Article dans une revue hal-03518954 v1
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Inorganic Sol−Gel Polymerization for Hydrogel Bioprinting

Titouan Montheil , Marie Maumus , Laurine Valot , Aurélien Lebrun , Jean Martínez et al.
ACS Omega, 2020, 5 (6), pp.2640-2647. ⟨10.1021/acsomega.9b03100⟩
Article dans une revue hal-02513894 v1
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Molecular complexes and main-chain organometallic polymers based on Janus bis(carbenes) fused to metalloporphyrins

Jean-François Longevial , Mamadou Lo , Aurélien Lebrun , Danielle Laurencin , Sébastien Clément et al.
Dalton Transactions, In press, 49, pp.7005-7014. ⟨10.1039/D0DT00594K⟩
Article dans une revue hal-02568903 v1
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DNA‐Based Asymmetric Inverse Electron‐Demand Hetero‐Diels–Alder

Justine Mansot , Jimmy Lauberteaux , Aurélien Lebrun , Marc Mauduit , Jean-Jacques Vasseur et al.
Chemistry - A European Journal, 2020, 26 (16), pp.3519-3523. ⟨10.1002/chem.202000516⟩
Article dans une revue hal-02512892 v1
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Unveiling the Structure and Reactivity of Fatty-Acid Based (Nano)materials Thanks to Efficient and Scalable 17O and 18O-Isotopic Labeling Schemes

Jessica Špačková , Charlyn Fabra , Sébastien Mittelette , Emeline Gaillard , Chia-Hsin Chen et al.
Journal of the American Chemical Society, 2020, 142 (50), pp.21068-21081. ⟨10.1021/jacs.0c09383⟩
Article dans une revue hal-03117231 v1
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Iron-Catalyzed Enantioselective Intramolecular Inverse Electron-Demand Hetero Diels–Alder Reactions: An Access to Bicyclic Dihydropyran Derivatives

Jimmy Lauberteaux , Aurélien Lebrun , Arie van Der Lee , Marc Mauduit , Renata Marcia de Figueiredo et al.
Organic Letters, 2019, 21 (24), pp.10007-10012. ⟨10.1021/acs.orglett.9b03752⟩
Article dans une revue hal-02429682 v1

Vinyl-aziridines and cyclopropanes in Pd-catalyzed (3+2)-cycloaddition reactions with cyclic N-sulfonyl imines

Kim Spielmann , Eleonora Tosi , Aurélien Lebrun , Gilles Niel , Arie van Der Lee et al.
Tetrahedron, 2018, 74 (45), pp.6497 - 6511. ⟨10.1016/j.tet.2018.09.040⟩
Article dans une revue hal-01892430 v1

Cofacial porphyrin dimers assembled from N-heterocyclic carbene–metal bonds

Clémence Rose , Aurélien Lebrun , Sébastien Clément , Sébastien Richeter
Chemical Communications, 2018, 54 (69), pp.9603 - 9606. ⟨10.1039/C8CC05707A⟩
Article dans une revue hal-01862544 v1

A multinuclear NMR perspective on the complexation between bisboronic acids and bisbenzoxaboroles with cis -diols

Adèle Larcher , Aurélien Lebrun , Michael Smietana , Danielle Laurencin
New Journal of Chemistry, 2018, 42 (4), pp.2815 - 2823. ⟨10.1039/C7NJ04143H⟩
Article dans une revue hal-01708542 v1
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Fused Bis-lactams to Spirolactams: A New Member of the Family of Ring- Contraction Reaction

Guilhem Chaubet , Mathéo Berthet , Morgane Pasco , Guillaume Cazals , Aurelien Lebrun et al.
Letters in Organic Chemistry, 2018, 15 (12), pp.1046-1055. ⟨10.2174/1570178615666180326160131⟩
Article dans une revue hal-02388789 v1

Hydrophobic alpha,alpha-Disubstituted Disilylated TESDpg Induces Incipient 3 10 -Helix in Short Tripeptide Sequence

Roberto Fanelli , Dorothée Berthomieu , Claude Didierjean , Abdelatif Doudouh , Aurélien Lebrun et al.
Organic Letters, 2017, 19 (11), pp.2937 - 2940. ⟨10.1021/acs.orglett.7b01172⟩
Article dans une revue hal-01552320 v1

Porphyrins Conjugated with Peripheral Thiolato Gold(I) Complexes for Enhanced Photodynamic Therapy

Jean-François Longevial , Khaled El cheikh , Dina Aggad , Aurélien Lebrun , Arie Van der lee et al.
Chemistry - A European Journal, 2017, 23, pp.14017-14026. ⟨10.1002/chem.201702975⟩
Article dans une revue hal-01613027 v1

Oxa-diketopiperazines: Access and Conformational Analysis of Potential Turn Inducers

Mathéo Berthet , Aurélien Lebrun , Arnaud Martel , Thomas Cheviet , Jean Martinez et al.
ChemistrySelect, 2017, 2 (21), pp.5824-5827. ⟨10.1002/slct.201701393⟩
Article dans une revue hal-02313808 v1

A Catalytically Competent Terpene Synthase Inferred Using Ancestral Sequence Reconstruction Strategy

Daniele Guzzetti , Aurelien Lebrun , Maeva Subileau , Estelle Grousseau , Eric Dubreucq et al.
ACS Catalysis, 2016, 6 (8), pp.5345 - 5349. ⟨10.1021/acscatal.6b01332⟩
Article dans une revue hal-01506512 v1

N-Pyrrolidine-based alpha/beta-peptides incorporating ABOC, a constrained bicyclic beta-amino acid, for asymmetric aldol reaction catalysis

Pierre Milbeo , Kelly Maurent , Laure Moulat , Aurelien Lebrun , Claude Didierjean et al.
Tetrahedron, 2016, 72 (13), pp.1706-1715. ⟨10.1016/j.tet.2016.02.027⟩
Article dans une revue hal-01532027 v1

Selenazolidine: a selenium containing proline surrogate in peptide science

E. Cordeau , S. Cantel , D. Gagne , A. Lebrun , J. Martinez et al.
Organic & Biomolecular Chemistry, 2016, 14 (34), pp.8101-8108. ⟨10.1039/C6OB01450J⟩
Article dans une revue hal-03564292 v1

Synthesis under moderate pressure of 3-imidazo[1,2- a ]pyridinylidene pyrrol-2-ones

Nicolas Masurier , Aurélien Lebrun , Damien Canitrot , Jean-Michel Chezal , Emmanuel Moreau
Tetrahedron Letters, 2016, 57 (24), pp.2583-2586. ⟨10.1016/j.tetlet.2016.04.093⟩
Article dans une revue istex hal-03564389 v1

Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives

Cécile Echalier , Alexandra Kalistratova , Jeremie Ciccione , Aurelien Lebrun , Baptiste Legrand et al.
RSC Advances, 2016, ⟨10.1039/c6ra06075g⟩
Article dans une revue hal-01345976 v1

Straightforward synthesis towards mono and bis-phosphonic acid functionalised β-cyclodextrins

April Marquick , Jean-Louis Montero , Aurélien Lebrun , Véronique Barragan-Montero
Tetrahedron, 2015, 71 (10), pp.1616-1621. ⟨10.1016/j.tet.2014.12.019⟩
Article dans une revue hal-03592418 v1
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Synthesis and structural characterization of monomeric and dimeric peptide nucleic acids prepared by using microwave-promoted multicomponent reactions

Reuben Ovadia , Aurelien Lebrun , Ivan Barvik , Jean-Jacques Vasseur , Carine Baraguey et al.
Organic & Biomolecular Chemistry, 2015, 13, pp.11052-11071. ⟨10.1039/c5ob01604e⟩
Article dans une revue hal-01438999 v1

From Diketopiperazines to Hydantoins: An Unprecedented Rearrangement

Guilhem Chaubet , Guillaume Cazals , Aurélien Lebrun , Jean Martinez , Isabelle Parrot
SYNLETT, 2014, 25 (4), pp.574-578. ⟨10.1055/s-0033-1340622⟩
Article dans une revue hal-00951723 v1

Thiazole-Based γ-Building Blocks as Reverse-Turn Mimetic to Design a Gramicidin S Analogue: Conformational and Biological Evaluation

Baptiste Legrand , Loic Mathieu , Aurélien Lebrun , Soahary Andriamanarivo , Vincent Lisowski et al.
Chemistry - A European Journal, 2014, 20 (22), pp.6713-6720. ⟨10.1002/chem.201402190⟩
Article dans une revue istex hal-02912610 v1

Silaproline Helical Mimetics Selectively Form an All-trans PPII Helix

Charlotte Martin , Baptiste Legrand , Aurélien Lebrun , Dorothée Berthomieu , Jean Martinez et al.
Chemistry - A European Journal, 2014, 20 (44), pp.1420-14244. ⟨10.1002/chem.201404820⟩
Article dans une revue istex hal-01078148 v1

Synthesis of Homopolypeptides with PPII Structure

Charlotte Martin , Aurélien Lebrun , Jean Martinez , Florine Cavelier
Journal of Polymer Science, 2013, 51, pp.3103-3109. ⟨10.1002/pola.26705⟩
Article dans une revue istex hal-00838581 v1
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Stereoselective synthesis of original spirolactams displaying promising folded structures.

Guilhem Chaubet , Thibault Coursindel , Xavier Morelli , Stéphane Betzi , Philippe Roche et al.
Organic & Biomolecular Chemistry, 2013, 11 (28), pp.4719-26. ⟨10.1039/c3ob40643a⟩
Article dans une revue hal-00871067 v1

Synthesis of trifluoromethyl cyclohexyl, cyclohexenyl and aryl compounds via stepwise Robinson annulation

Fabien Massicot , Alex Mor Iriarte , Thierry Brigaud , Aurélien Lebrun , Charles Portella
Organic & Biomolecular Chemistry, 2011, 9 (2), pp.600-603. ⟨10.1039/c0ob00518e⟩
Article dans une revue hal-03561540 v1

Photochemical electron transfer mediated addition of naphthylamine derivatives to electron deficient alkenes

Rabih Jahjah , Abdoulaye Gassama , Frédéric Dumur , Sinisa Marinkovi C , Sabine Richert et al.
Journal of Organic Chemistry, 2011, 76, pp.7104-7118. ⟨10.1021/jo201080m⟩
Article dans une revue hal-01020223 v1

Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds

Sébastien Richeter , Ludivine Poyac , Clémence Rose , Mohammad Wahiduzzaman , Aurélien Lebrun et al.
International Symposium on Functional π-Electron Systems, Jun 2023, Raleigh (NC), United States
Poster de conférence hal-04751522 v1

Synthesis and Encapsulation Properties of Porphyrin Cages Assembled from N-heterocyclic Carbene-Metal Bonds

Ludivine Poyac , Clémence Rose , Mohammad Wahiduzzaman , Aurélien Lebrun , Guillaume Cazals et al.
International Conference on Porphyrins and Phthalocyanines 12, Madrid, Spain, 10-15 July 2022, Jul 2022, Madrid, Spain
Poster de conférence hal-04762731 v1