Caroline Smet-Nocca

34
Documents

Publications

Publications

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Effect of PHF-1 hyperphosphorylation on the seeding activity of C-terminal Tau fragments

Léa El Hajjar , Emmanuelle Boll , François-Xavier Cantrelle , Clarisse Bridot , Isabelle Landrieu et al.
Scientific Reports, 2025, 15 (9975), ⟨10.1038/s41598-025-91867-3⟩
Article dans une revue hal-05004956 v1
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Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation

Alessia Lasorsa , Hamida Merzougui , François-Xavier Cantrelle , Giuseppe Sicoli , Elian Dupré et al.
Biophysical Chemistry, 2024, Part of special issue Biophysical, Biochemical, and Cellular Events Underlying Proteinopathies Edited by Carmelo La Rosa, Danilo Milardi, Magdalena Ivanova, Andisheh Abedini, Lucie Khemtemourian, Ayyalusamy Ramamoorthy, 305 (107155), pp.107155. ⟨10.1016/j.bpc.2023.107155⟩
Article dans une revue hal-04440623 v1

Regulation of Glycogen Synthase Kinase-3β by Phosphorylation and O-β-Linked N-Acetylglucosaminylation: Implications on Tau Protein Phosphorylation

Léa El Hajjar , Adeline Page , Clarisse Bridot , François-Xavier Cantrelle , Isabelle Landrieu et al.
Biochemistry, 2024, 63 (12), pp.1513-1533. ⟨10.1021/acs.biochem.4c00095⟩
Article dans une revue hal-04745026 v1
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Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools

Isabelle Landrieu , Elian Dupré , Davy Sinnaeve , Léa El Hajjar , Caroline Smet-Nocca
Frontiers in Chemistry, 2022, 10, pp.886382. ⟨10.3389/fchem.2022.886382⟩
Article dans une revue hal-03841022 v1
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Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

François-Xavier Cantrelle , Anne Loyens , Xavier Trivelli , Oliver Reimann , Clément Despres et al.
Frontiers in Molecular Neuroscience, 2021, 14, pp.661368. ⟨10.3389/fnmol.2021.661368⟩
Article dans une revue hal-03428106 v1

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

Clément Despres , Jing Di , François-Xavier Cantrelle , Zizheng Li , Isabelle Huvent et al.
ACS Chemical Biology, 2019, 14 (6), pp.1363-1379. ⟨10.1021/acschembio.9b00325⟩
Article dans une revue hal-02317189 v1
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Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

Pascale Barbier , Orgeta Zejneli , Marlène Martinho , Alessia Lasorsa , Valérie Belle et al.
Frontiers in Aging Neuroscience, 2019, 11, ⟨10.3389/fnagi.2019.00204⟩
Article dans une revue hal-02279660 v1
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The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

Yann Fichou , Youssra K Al-Hilaly , François Devred , Caroline Smet-Nocca , Philipp O Tsvetkov et al.
Acta Neuropathologica Communications, 2019, 7 (1), ⟨10.1186/s40478-019-0682-x⟩
Article dans une revue hal-02055894 v1

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator

Michael Nshanian , Carter Lantz , Piriya Wongkongkathep , Thomas Schrader , Frank-Gerrit Klärner et al.
Journal of The American Society for Mass Spectrometry, 2019, 30 (1), pp.16-23. ⟨10.1007/s13361-018-2027-6⟩
Article dans une revue hal-02543395 v1

The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation

Caroline Smet-Nocca , Adeline Page , Francois-Xavier Cantrelle , Eleni Nikolakaki , Isabelle Landrieu et al.
Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (4), pp.825-835. ⟨10.1016/j.bbagen.2018.01.007⟩
Article dans une revue hal-02353573 v1

Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

Gwendoline Bourré , François-Xavier Cantrelle , Amina Kamah , Béatrice Chambraud , Isabelle Landrieu et al.
Frontiers in Endocrinology, 2018, 9, ⟨10.3389/fendo.2018.00595⟩
Article dans une revue hal-02337415 v1
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Identification of the Tau phosphorylation pattern that drives its aggregation

Clement Despres , Cillian Byrne , Haoling Qi , François-Xavier Cantrelle , Isabelle Huvent et al.
Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩
Article dans une revue hal-01620128 v1

Semi-synthesis of a tag-free O -GlcNAcylated tau protein by sequential chemoselective ligation

Sergej Schwagerus , Oliver Reimann , Clement Despres , Caroline Smet-Nocca , Christian P. R. Hackenberger
Journal of Peptide Science, 2016, 22 (5), pp.327 - 333. ⟨10.1002/psc.2870⟩
Article dans une revue istex hal-01389835 v1

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Clément Danis , Clement Despres , Luiza M. Bessa , Idir Malki , Hamida Merzougui et al.
Journal of visualized experiments : JoVE, 2016, 118, ⟨10.3791/55001⟩
Article dans une revue hal-01620152 v1

Traceless Purification and Desulfurization of Tau Protein Ligation Products

Oliver Reimann , Caroline Smet-Nocca , Christian P. R. Hackenberger
Angewandte Chemie International Edition, 2015, 54 (1), pp.306 - 310. ⟨10.1002/anie.201408674⟩
Article dans une revue istex hal-01389837 v1

Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure

Emilie Dubois-Deruy , Aude Belliard , Paul Mulder , Marion Bouvet , Caroline Smet-Nocca et al.
Cardiovascular Research, 2015, 107 (1), pp.56-65. ⟨10.1093/cvr/cvv136⟩
Article dans une revue inserm-03833102 v1

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation.

Haoling Qi , François-Xavier Cantrelle , Houda Benhelli-Mokrani , Caroline Smet-Nocca , Luc Buée et al.
Biochemistry, 2015, 54 (7), pp.1525-33
Article dans une revue hal-01145987 v1

Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein.

Amina Kamah , Isabelle Huvent , François-Xavier Cantrelle , Haoling Qi , Guy Lippens et al.
Biochemistry, 2014, 53 (18), pp.3020-32. ⟨10.1021/bi500006v⟩
Article dans une revue hal-01077868 v1

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge.

Isabelle Huvent , Amina Kamah , François-Xavier Cantrelle , Nicolas Barois , Christian Slomianny et al.
Biochemical and Biophysical Research Communications, 2014, 445 (2), pp.299-303. ⟨10.1016/j.bbrc.2014.01.161⟩
Article dans une revue hal-01077911 v1

A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes

Arndt G. Benecke , Sebastian Eilebrecht , Hélène Léger , Caroline Smet-Nocca , Amel Attmane-Elakeb et al.
Genomics, Proteomics and Bioinformatics, 2014, 12 (1), pp.8-18. ⟨10.1016/j.gpb.2013.11.001⟩
Article dans une revue hal-01544142 v1

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.

Caroline Smet-Nocca , Hélène Launay , Jean-Michel Wieruszeski , Guy Lippens , Isabelle Landrieu
Journal of Biomolecular NMR, 2013, 55 (4), pp.323-37. ⟨10.1007/s10858-013-9716-z⟩
Article dans une revue istex hal-00903359 v1

50nm scale localization of single unmodified, isotopically enriched, proteins in cells

Anthony Delaune , Armelle Cabin-Flaman , Guillaume Legent , David Gibouin , Caroline Smet-Nocca et al.
PLoS ONE, 2013, 8, pp.e56559
Article dans une revue hal-04441019 v1

50nm-Scale Localization of Single Unmodified, Isotopically Enriched, Proteins in Cells

Anthony Delaune , Armelle Cabin-Flaman , Guillaume Legent , David Gibouin , Caroline Smet-Nocca et al.
PLoS ONE, 2013, 8 (2), pp.e56559. ⟨10.1371/journal.pone.0056559⟩
Article dans une revue hal-01544145 v1

Cell signaling, post-translational protein modifications and NMR spectroscopy.

Francois-Xavier Theillet , Caroline Smet-Nocca , Stamatios Liokatis , Rossukon Thongwichian , Jonas Kosten et al.
Journal of Biomolecular NMR, 2012, 54 (3), pp.217-36. ⟨10.1007/s10858-012-9674-x⟩
Article dans une revue hal-00765863 v1

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.

Peter Borghgraef , Clément Menuet , Clara Theunis , Justin V Louis , Herman Devijver et al.
PLoS ONE, 2012, pp.e84442
Article dans une revue hal-01077942 v1

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

Caroline Smet-Nocca , Malgorzata Broncel , Jean-Michel Wieruszeski , Caroline Tokarski , Xavier Hanoulle et al.
Molecular BioSystems, 2011, 7 (5), pp.1420-9. ⟨10.1039/c0mb00337a⟩
Article dans une revue hal-00586849 v1

Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2.

Furqan Sami , Caroline Smet-Nocca , Meera Khan , Isabelle Landrieu , Guy Lippens et al.
Biochemistry, 2011, 50 (30), pp.6567-78. ⟨10.1021/bi200553e⟩
Article dans une revue hal-00618273 v1

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

Isabelle Landrieu , Caroline Smet-Nocca , Laziza Amniai , Justin Vijay Louis , Jean-Michel Wieruszeski et al.
PLoS ONE, 2011, 6 (6), pp.e21521. ⟨10.1371/journal.pone.0021521⟩
Article dans une revue hal-00618270 v1

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease.

Isabelle Landrieu , Arnaud Leroy , Caroline Smet-Nocca , Isabelle Huvent , Laziza Amniai et al.
Biochemical Society Transactions, 2010, 38 (4), pp.1006-11. ⟨10.1042/BST0381006⟩
Article dans une revue hal-00586933 v1

The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins.

Hélène Hodak , Alexandre Wohlkönig , Caroline Smet-Nocca , Hervé Drobecq , Jean-Michel Wieruszeski et al.
Journal of Molecular Biology, 2008, 376 (2), pp.414-26. ⟨10.1016/j.jmb.2007.10.088⟩
Article dans une revue istex hal-00273348 v1