Caroline Smet-Nocca

Documents

Publications

	Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation Alessia Lasorsa , Hamida Merzougui , François-Xavier Cantrelle , Giuseppe Sicoli , Elian Dupré Biophysical Chemistry, 2024, Part of special issue Biophysical, Biochemical, and Cellular Events Underlying Proteinopathies Edited by Carmelo La Rosa, Danilo Milardi, Magdalena Ivanova, Andisheh Abedini, Lucie Khemtemourian, Ayyalusamy Ramamoorthy, 305 (107155), pp.107155. ⟨10.1016/j.bpc.2023.107155⟩ Journal articles hal-04440623v1
	Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools Isabelle Landrieu , Elian Dupré , Davy Sinnaeve , Léa El Hajjar , Caroline Smet-Nocca Frontiers in Chemistry, 2022, 10, pp.886382. ⟨10.3389/fchem.2022.886382⟩ Journal articles hal-03841022v1
	Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates François-Xavier Cantrelle , Anne Loyens , Xavier Trivelli , Oliver Reimann , Clément Despres Frontiers in Molecular Neuroscience, 2021, 14, pp.661368. ⟨10.3389/fnmol.2021.661368⟩ Journal articles hal-03428106v1
	Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors Clément Despres , Jing Di , François-Xavier Cantrelle , Zizheng Li , Isabelle Huvent ACS Chemical Biology, 2019, 14 (6), pp.1363-1379. ⟨10.1021/acschembio.9b00325⟩ Journal articles hal-02317189v1
	Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator Michael Nshanian , Carter Lantz , Piriya Wongkongkathep , Thomas Schrader , Frank-Gerrit Klärner Journal of The American Society for Mass Spectrometry, 2019, 30 (1), pp.16-23. ⟨10.1007/s13361-018-2027-6⟩ Journal articles hal-02543395v1
	The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention? Yann Fichou , Youssra K Al-Hilaly , François Devred , Caroline Smet-Nocca , Philipp O Tsvetkov Acta Neuropathologica Communications, 2019, 7 (1), ⟨10.1186/s40478-019-0682-x⟩ Journal articles hal-02055894v1
	Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects Pascale Barbier , Orgeta Zejneli , Marlène Martinho , Alessia Lasorsa , Valérie Belle Frontiers in Aging Neuroscience, 2019, 11, ⟨10.3389/fnagi.2019.00204⟩ Journal articles hal-02279660v1
	Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy Gwendoline Bourré , François-Xavier Cantrelle , Amina Kamah , Béatrice Chambraud , Isabelle Landrieu Frontiers in Endocrinology, 2018, 9, ⟨10.3389/fendo.2018.00595⟩ Journal articles hal-02337415v1
	The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation Caroline Smet-Nocca , Adeline Page , Francois-Xavier Cantrelle , Eleni Nikolakaki , Isabelle Landrieu Biochimica et Biophysica Acta (BBA) - General Subjects, 2018, 1862 (4), pp.825-835. ⟨10.1016/j.bbagen.2018.01.007⟩ Journal articles hal-02353573v1
	Identification of the Tau phosphorylation pattern that drives its aggregation Clement Despres , Cillian Byrne , Haoling Qi , François-Xavier Cantrelle , Isabelle Huvent Proceedings of the National Academy of Sciences of the United States of America, 2017, 114 (34), pp.9080 - 9085. ⟨10.1073/pnas.1708448114⟩ Journal articles hal-01620128v1
	Semi-synthesis of a tag-free O -GlcNAcylated tau protein by sequential chemoselective ligation Sergej Schwagerus , Oliver Reimann , Clement Despres , Caroline Smet-Nocca , Christian P. R. Hackenberger Journal of Peptide Science, 2016, 22 (5), pp.327 - 333. ⟨10.1002/psc.2870⟩ Journal articles hal-01389835v1
	Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins Clément Danis , Clement Despres , Luiza M. Bessa , Idir Malki , Hamida Merzougui Journal of visualized experiments : JoVE, 2016, 118, ⟨10.3791/55001⟩ Journal articles hal-01620152v1
	Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure Emilie Dubois-Deruy , Aude Belliard , Paul Mulder , Marion Bouvet , Caroline Smet-Nocca Cardiovascular Research, 2015, 107 (1), pp.56-65. ⟨10.1093/cvr/cvv136⟩ Journal articles inserm-03833102v1
	Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation. Haoling Qi , François-Xavier Cantrelle , Houda Benhelli-Mokrani , Caroline Smet-Nocca , Luc Buée Biochemistry, 2015, 54 (7), pp.1525-33 Journal articles hal-01145987v1
	Traceless Purification and Desulfurization of Tau Protein Ligation Products Oliver Reimann , Caroline Smet-Nocca , Christian P. R. Hackenberger Angewandte Chemie International Edition, 2015, 54 (1), pp.306 - 310. ⟨10.1002/anie.201408674⟩ Journal articles hal-01389837v1
	Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein. Amina Kamah , Isabelle Huvent , François-Xavier Cantrelle , Haoling Qi , Guy Lippens Biochemistry, 2014, 53 (18), pp.3020-32. ⟨10.1021/bi500006v⟩ Journal articles hal-01077868v1
	A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes Arndt G. Benecke , Sebastian Eilebrecht , Hélène Léger , Caroline Smet-Nocca , Amel Attmane-Elakeb Genomics, Proteomics and Bioinformatics, 2014, 12 (1), pp.8-18. ⟨10.1016/j.gpb.2013.11.001⟩ Journal articles hal-01544142v1
	A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge. Isabelle Huvent , Amina Kamah , François-Xavier Cantrelle , Nicolas Barois , Christian Slomianny Biochemical and Biophysical Research Communications, 2014, 445 (2), pp.299-303. ⟨10.1016/j.bbrc.2014.01.161⟩ Journal articles hal-01077911v1
	50nm-Scale Localization of Single Unmodified, Isotopically Enriched, Proteins in Cells Anthony Delaune , Armelle Cabin-Flaman , Guillaume Legent , David Gibouin , Caroline Smet-Nocca PLoS ONE, 2013, 8 (2), pp.e56559. ⟨10.1371/journal.pone.0056559⟩ Journal articles hal-01544145v1
	Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA. Caroline Smet-Nocca , Hélène Launay , Jean-Michel Wieruszeski , Guy Lippens , Isabelle Landrieu Journal of Biomolecular NMR, 2013, 55 (4), pp.323-37. ⟨10.1007/s10858-013-9716-z⟩ Journal articles hal-00903359v1
	50nm scale localization of single unmodified, isotopically enriched, proteins in cells Anthony Delaune , Armelle Cabin-Flaman , Guillaume Legent , David Gibouin , Caroline Smet-Nocca PLoS ONE, 2013, 8, pp.e56559 Journal articles hal-04441019v1
	Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice. Peter Borghgraef , Clément Menuet , Clara Theunis , Justin V Louis , Herman Devijver PLoS ONE, 2012, pp.e84442 Journal articles hal-01077942v1
	Cell signaling, post-translational protein modifications and NMR spectroscopy. Francois-Xavier Theillet , Caroline Smet-Nocca , Stamatios Liokatis , Rossukon Thongwichian , Jonas Kosten Journal of Biomolecular NMR, 2012, 54 (3), pp.217-36. ⟨10.1007/s10858-012-9674-x⟩ Journal articles hal-00765863v1
	Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau. Isabelle Landrieu , Caroline Smet-Nocca , Laziza Amniai , Justin Vijay Louis , Jean-Michel Wieruszeski PLoS ONE, 2011, 6 (6), pp.e21521. ⟨10.1371/journal.pone.0021521⟩ Journal articles hal-00618270v1
	Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation. Caroline Smet-Nocca , Malgorzata Broncel , Jean-Michel Wieruszeski , Caroline Tokarski , Xavier Hanoulle Molecular BioSystems, 2011, 7 (5), pp.1420-9. ⟨10.1039/c0mb00337a⟩ Journal articles hal-00586849v1
	Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2. Furqan Sami , Caroline Smet-Nocca , Meera Khan , Isabelle Landrieu , Guy Lippens Biochemistry, 2011, 50 (30), pp.6567-78. ⟨10.1021/bi200553e⟩ Journal articles hal-00618273v1
	NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease. Isabelle Landrieu , Arnaud Leroy , Caroline Smet-Nocca , Isabelle Huvent , Laziza Amniai Biochemical Society Transactions, 2010, 38 (4), pp.1006-11. ⟨10.1042/BST0381006⟩ Journal articles hal-00586933v1
	The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins. Hélène Hodak , Alexandre Wohlkönig , Caroline Smet-Nocca , Hervé Drobecq , Jean-Michel Wieruszeski Journal of Molecular Biology, 2008, 376 (2), pp.414-26. ⟨10.1016/j.jmb.2007.10.088⟩ Journal articles hal-00273348v1

	Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications Clément Danis , Elian Dupré , Xavier Hanoulle , Isabelle Landrieu , Alessia Lasorsa Advanced in Experimental Medical Biology, pp.35-45, 2019, ⟨10.1007/978-981-32-9358-8_3⟩ Book sections hal-02506938v1

	Etude des interactions entre la peptidyl-prolyl cis/trans isomérase Pin1 et la protéine microtubulaire Tau. Recherche d'inhibiteurs ciblant la liaison de Pin1 à ses substrats phosphorylés Caroline Smet-Nocca Biochimie [q-bio.BM]. Université du Droit et de la Santé - Lille II, 2004. Français. ⟨NNT : ⟩ Theses tel-00354986v1

	Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ? Fabien Ferrage , Pierre Florian , Guy Lippens , Emmanuel Maes , Guido Pintacuda Réunion des utilisateurs RMN de Bruker France, Nov 2023, Lille, France Conference papers hal-04470791v1

Caroline Smet-Nocca

Publications

Magnetic resonance investigation of conformational responses of tau protein to specific phosphorylation

Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools

Phosphorylation and O-GlcNAcylation of the PHF-1 Epitope of Tau Protein Induce Local Conformational Changes of the C-Terminus and Modulate Tau Self-Assembly Into Fibrillar Aggregates

Major Differences between the Self-Assembly and Seeding Behavior of Heparin-Induced and in Vitro Phosphorylated Tau and Their Modulation by Potential Inhibitors

Native Top-Down Mass Spectrometry and Ion Mobility Spectrometry of the Interaction of Tau Protein with a Molecular Tweezer Assembly Modulator

The elusive tau molecular structures: can we translate the recent breakthroughs into new targets for intervention?

Role of Tau as a Microtubule-Associated Protein: Structural and Functional Aspects

Direct Crosstalk Between O-GlcNAcylation and Phosphorylation of Tau Protein Investigated by NMR Spectroscopy

The O-β-linked N-acetylglucosaminylation of the Lamin B receptor and its impact on DNA binding and phosphorylation

Identification of the Tau phosphorylation pattern that drives its aggregation

Semi-synthesis of a tag-free O -GlcNAcylated tau protein by sequential chemoselective ligation

Nuclear Magnetic Resonance Spectroscopy for the Identification of Multiple Phosphorylations of Intrinsically Disordered Proteins

Interplay between troponin T phosphorylation and O-N-acetylglucosaminylation in ischaemic heart failure

Nuclear magnetic resonance spectroscopy characterization of interaction of Tau with DNA and its regulation by phosphorylation.

Traceless Purification and Desulfurization of Tau Protein Ligation Products

Nuclear magnetic resonance analysis of the acetylation pattern of the neuronal Tau protein.

A TDG/CBP/RARα Ternary Complex Mediates the Retinoic Acid-dependent Expression of DNA Methylation-sensitive Genes

A functional fragment of Tau forms fibers without the need for an intermolecular cysteine bridge.

50nm-Scale Localization of Single Unmodified, Isotopically Enriched, Proteins in Cells

Unraveling a phosphorylation event in a folded protein by NMR spectroscopy: phosphorylation of the Pin1 WW domain by PKA.

50nm scale localization of single unmodified, isotopically enriched, proteins in cells

Increasing brain protein O-GlcNAc-ylation mitigates breathing defects and mortality of Tau.P301L mice.

Cell signaling, post-translational protein modifications and NMR spectroscopy.

Molecular implication of PP2A and Pin1 in the Alzheimer's disease specific hyperphosphorylation of Tau.

Identification of O-GlcNAc sites within peptides of the Tau protein and their impact on phosphorylation.

Molecular Basis for an Ancient Partnership between Prolyl Isomerase Pin1 and Phosphatase Inhibitor-2.

NMR spectroscopy of the neuronal tau protein: normal function and implication in Alzheimer's disease.

The peptidyl-prolyl isomerase and chaperone Par27 of Bordetella pertussis as the prototype for a new group of parvulins.

Nuclear Magnetic Resonance Spectroscopy Insights into Tau Structure in Solution: Impact of Post-translational Modifications

Etude des interactions entre la peptidyl-prolyl cis/trans isomérase Pin1 et la protéine microtubulaire Tau. Recherche d'inhibiteurs ciblant la liaison de Pin1 à ses substrats phosphorylés

Premier spectromètre RMN 1,2 GHz français : quelles nouvelles possibilités pour l’analyse ?