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Charles Desmarchelier

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The Incorporation of Curcuminoids in Gamma‐Cyclodextrins Improves Their Poor Bioaccessibility, Which Is due to Both Their Very Low Incorporation into Mixed Micelles and Their Partial Adsorption on Food

Patrick Borel , Faiza Hammaz , Lucie Lecourt , Grégory Marconot , Guillian Gillet
Molecular Nutrition and Food Research, 2023, 67 (12), ⟨10.1002/mnfr.202200798⟩
Journal articles hal-04155337v1
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Vitamin A deficiency during the perinatal period induces changes in vitamin A metabolism in the offspring. The regulation of intestinal vitamin A metabolism via ISX occurs only in male rats severely vitamin A-deficient

Patrick Borel , Romane Troadec , Morgane Damiani , Charlotte Halimi , Marion Nowicki
European Journal of Nutrition, 2023, 62, pp.633-646. ⟨10.1007/s00394-022-03019-2⟩
Journal articles hal-03794244v1
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The zeaxanthin present in a tomato line rich in this carotenoid is as bioavailable as that present in the food sources richest in this xanthophyll

Lisa Morand-Laffargue , Joseph Hirschberg , Charlotte Halimi , Charles Desmarchelier , Patrick Borel
Food Research International, 2023, 168, pp.112751. ⟨10.1016/j.foodres.2023.112751⟩
Journal articles hal-04203812v1
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Black soldier fly larvae (Hermetia Illucens) as a sustainable and concentrated source of bioavailable lutein for feed

L. Morand-Laffargue , B. Creton , Charlotte Halimi , D. Sabatier , C. Desmarchelier
Journal of Insects as Food and Feed, 2023, pp.1-12. ⟨10.1163/23524588-20230107⟩
Journal articles hal-04332115v1

Post-Harvest Atmospheric Pressure and Composition Modify the Concentration and Bioaccessibility of α- and β-Carotene in Carrots and Sweet Potatoes

Batoul Hamieh , Patrick Borel , Sana Raouche , Laurie Bruzzese , Nabil Adjriou
Foods, 2023, 12 (23), pp.4262. ⟨10.3390/foods12234262⟩
Journal articles hal-04391296v1
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The Interindividual Variability of Phytofluene Bioavailability is Associated with a Combination of Single Nucleotide Polymorphisms

Mark Pretzel Zumaraga , Patrick Borel , Romain Bott , Marion Nowicki , Denis Lairon
Molecular Nutrition and Food Research, 2023, 67 (2), ⟨10.1002/mnfr.202200580⟩
Journal articles hal-04203835v1
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Reduction of pulse “antinutritional” content by optimizing pulse canning process is insufficient to improve fat-soluble vitamin bioavailability

Tiffany Antoine , Stéphane Georgé , Alexandre Leca , Charles Desmarchelier , Charlotte Halimi
Food Chemistry, 2022, 370, pp.131021. ⟨10.1016/j.foodchem.2021.131021⟩
Journal articles hal-03346447v1
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Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence

Mohammad M H Abdullah , Itzel Vazquez-Vidal , David J Baer , James D House , Peter J H Jones
Nutrients, 2021, 13 (2), pp.695. ⟨10.3390/nu13020695⟩
Journal articles hal-03224469v1

A combination of single nucleotide polymorphisms is associated with the interindividual variability in the blood lipid response to dietary fatty acid consumption in a randomized clinical trial

Ethendhar Rajendiran , Benoît Lamarche , Yongbo She , Vanu Ramprasath , Peter Eck
The American Journal of Clinical Nutrition, 2021, 114 (2), pp.564-577. ⟨10.1093/ajcn/nqab064⟩
Journal articles hal-03653354v1
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From carotenoid intake to carotenoid blood and tissue concentrations – implications for dietary intake recommendations

Volker Böhm , Georg Lietz , Begoña Olmedilla-Alonso , David Phelan , Emmanuelle Reboul
Nutrition Reviews, 2021, 79 (5), pp.544-573. ⟨10.1093/nutrit/nuaa008⟩
Journal articles hal-04203859v1
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Using black soldier fly larvae reared on fruits and vegetables waste as a sustainable dietary source of provitamin A carotenoids

Patrick Borel , Faiza Hammaz , Lisa Morand-Laffargue , Benjamin Creton , Charlotte Halimi
Food Chemistry, 2021, 359, pp.129911. ⟨10.1016/j.foodchem.2021.129911⟩
Journal articles hal-03206155v1
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Influence of soy and whey protein, gelatin and sodium caseinate on carotenoid bioaccessibility

Mohammed Iddir , Giulia Dingeo , Juan Felipe Porras Yaruro , Faiza Hammaz , Patrick Borel
Food and Function, 2020, 11 (6), pp.5446-5459. ⟨10.1039/d0fo00888e⟩
Journal articles hal-03158397v1
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A Combination of Single Nucleotide Polymorphisms is Associated with the Interindividual Variability of Cholesterol Bioavailability in Healthy Adult Males

Charles Desmarchelier , Estelle Wolff , Catherine Defoort , Marion Nowicki , Pierre‐emmanuel Morange
Molecular Nutrition and Food Research, 2020, 64 (22), pp.2000480. ⟨10.1002/mnfr.202000480⟩
Journal articles hal-03155917v1
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Effets de la matrice alimentaire sur la biodisponibilité des micronutriments et phytomicronutriments lipidiques

Charles Desmarchelier
Cahiers de Nutrition et de Diététique, 2020, 55 (5), pp.240-248. ⟨10.1016/j.cnd.2020.05.001⟩
Journal articles hal-03224403v1
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Comparison of the bioavailability and intestinal absorption sites of phytoene, phytofluene, lycopene and β-carotene

Paula Mapelli-Brahm , Marielle Margier , Charles Desmarchelier , Charlotte Halimi , Marion Nowicki
Food Chemistry, 2019, 300, 6 p. ⟨10.1016/j.foodchem.2019.125232⟩
Journal articles hal-02475161v1
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Effect of Nutrient and Micronutrient Intake on Chylomicron Production and Postprandial Lipemia

Charles Desmarchelier , Patrick Borel , Denis Lairon , Marie Maraninchi , Rene Valero
Nutrients, 2019, 11 (6), pp.1299. ⟨10.3390/nu11061299⟩
Journal articles hal-02488967v2
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Effect of Nutrient and Micronutrient Intake on Chylomicron Production and Postprandial Lipemia

Charles Desmarchelier , Patrick Borel , Denis Lairon , Marie Maraninchi , René Valéro
Nutrients, 2019, 11 (6), pp.1299. ⟨10.3390/nu11061299⟩
Journal articles hal-02487091v1

Nutrigenetics of Blood Cholesterol Concentrations: Towards Personalized Nutrition

Itzel Vazquez-Vidal , Charles Desmarchelier , Peter Jones
Current Cardiology Reports, 2019, 21 (5), ⟨10.1007/s11886-019-1124-x⟩
Journal articles hal-02487403v1
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Whey protein isolate modulates beta-carotene bioaccessibility depending on gastro-intestinal digestion conditions

Mohammed Iddir , Celal Degerli , Giulia Dingeo , Charles Desmarchelier , Thomas Schleeh
Food Chemistry, 2019, 291, pp.157-166. ⟨10.1016/j.foodchem.2019.04.003⟩
Journal articles hal-02487079v1
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Genetic variants in selenoprotein genes modulate biomarkers of selenium status in 1 response to Brazil nut supplementation (the SU.BRA.NUT study) 2

Janaina L. S. Donadio , Marcelo M. Rogero , Elvira M. Guerra-Shinohara , Fernando Barbosa Jr , Charles A Desmarchelier
Clinical Nutrition, 2019, 38 (2), pp.539-548. ⟨10.1016/j.clnu.2018.03.011⟩
Journal articles inserm-01761217v1
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ABCB1 (P-glycoprotein) regulates vitamin D absorption and contributes to its transintestinal efflux

Marielle Margier , Xavier Collet , Cédric Le May , Charles Desmarchelier , François André
FASEB Journal, 2019, 33 (2), pp.2084-2094. ⟨10.1096/fj.201800956R⟩
Journal articles hal-01986017v1
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β-Carotene in the human body: metabolic bioactivation pathways – from digestion to tissue distribution and excretion

Torsten Bohn , Charles Desmarchelier , Sedef El , Jaap Keijer , Evert van Schothorst
Proceedings of the Nutrition Society, 2019, 78 (1), pp.68-87. ⟨10.1017/S0029665118002641⟩
Journal articles hal-02487119v1
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Genetic factors involved in the bioavailability of tomato carotenoids.

Charles Desmarchelier , Jean-Francois Landrier , Patrick Borel
Current Opinion in Clinical Nutrition and Metabolic Care, 2018, 21 (6), pp.489-497. ⟨10.1097/MCO.0000000000000515⟩
Journal articles hal-01988648v1
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Bioavailability of Fat-Soluble Vitamins and Phytochemicals in Humans: Effects of Genetic Variation

Patrick Borel , Charles Desmarchelier
Annual Review of Nutrition, 2018, 38 (1), pp.69-96. ⟨10.1146/annurev-nutr-082117-051628⟩
Journal articles hal-01986022v1
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Magnesium affects spinach carotenoid bioaccessibility in vitro depending on intestinal bile and pancreatic enzyme concentrations

Joana Corte-Real , Charles Desmarchelier , Patrick Borel , Elke Richling , Lucien Hoffmann
Food Chemistry, 2018, 239, pp.751-759. ⟨10.1016/j.foodchem.2017.06.147⟩
Journal articles hal-01745361v1
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Molecular interactions governing the incorporation of cholecalciferol and retinyl-palmitate in mixed taurocholate-lipid micelles

Charles Desmarchelier , Véronique Rosilio , David Chapron , Ali Makky , Damien Preveraud
Food Chemistry, 2018, 250, pp.221 - 229. ⟨10.1016/j.foodchem.2018.01.063⟩
Journal articles hal-01757864v1
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Phytoene and Phytofluene Isolated from a Tomato Extract are Readily Incorporated in Mixed Micelles and Absorbed by Caco-2 Cells, as Compared to Lycopene, and SR-BI is Involved in their Cellular Uptake

Paula Mapelli-Brahm , Charles Desmarchelier , Marielle Margier , Emmanuelle Reboul , Antonio Meléndez Martínez
Molecular Nutrition and Food Research, 2018, 62 (22), pp.1800703. ⟨10.1002/mnfr.201800703⟩
Journal articles hal-01986021v1
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Comparison of the Micellar Incorporation and the Intestinal Cell Uptake of Cholecalciferol, 25-Hydroxycholecalciferol and 1-α-Hydroxycholecalciferol

Charles Desmarchelier , Marielle Margier , Damien Preveraud , Marion Nowicki , Véronique Rosilio
Nutrients, 2017, 9 (10), pp.1152. ⟨10.3390/nu9101152⟩
Journal articles hal-01745318v1
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Host-related factors explaining interindividual variability of carotenoid bioavailability and tissue concentrations in humans

Torsten Bohn , Charles Desmarchelier , Lars O. Dragsted , Charlotte S. Nielsen , Wilhelm Stahl
Molecular Nutrition and Food Research, 2017, 61 (6), Epub ahead of print. ⟨10.1002/mnfr.201600685⟩
Journal articles inserm-01480026v1
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Genetic Variations Associated with Vitamin A Status and Vitamin A Bioavailability

Patrick Borel , Charles Desmarchelier
Nutrients, 2017, 9 (3), pp.E246. ⟨10.3390/nu9030246⟩
Journal articles inserm-01487938v1
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Negative effects of divalent mineral cations on the bioaccessibility of carotenoids from plant food matrices and related physical properties of gastro-intestinal fluids

Joana Corte-Real , Marie Bertucci , Christos Soukoulis , Charles Desmarchelier , Patrick Borel
Food and Function, 2017, 8 (3), pp.1008-1019. ⟨10.1039/C6FO01708H⟩
Journal articles inserm-01479975v2
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Overview of carotenoid bioavailability determinants: From dietary factors to host genetic variations

Charles Desmarchelier , Patrick Borel
Trends in Food Science and Technology, 2017, 69 (B), Epub ahead of print. ⟨10.1016/j.tifs.2017.03.002⟩
Journal articles inserm-01499484v1
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Are lutein, lycopene, and β-carotene lost through the digestive process?

Rachel E. Kopec , Béatrice Gleize , Patrick Borel , Charles Desmarchelier , Catherine Caris-Veyrat
Food and Function, 2017, 8 (4), pp.1494-1503. ⟨10.1039/C7FO00021A⟩
Journal articles inserm-01499474v1
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SEPP1 polymorphisms modulate serum glucose and lipid response to Brazil nut supplementation

Janaina L. S. Donadio , Marcelo M. Rogero , Elvira M. Guerra-Shinohara , Charles Desmarchelier , Patrick Borel
European Journal of Nutrition, 2017, 57 (5), Epub ahead of print. ⟨10.1007/s00394-017-1470-7⟩
Journal articles inserm-01531459v1
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Impact of bariatric surgery on apolipoprotein C-III levels and lipoprotein distribution in obese human subjects

Marie Maraninchi , Nadege Padilla , Sophie Béliard , Bruno Berthet , Juan-Patricio Nogueira
Journal of clinical lipidology, 2017, 11 (2), pp.495 - 506.e3. ⟨10.1016/j.jacl.2017.02.012⟩
Journal articles hal-01757597v1
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Genetic Variations Involved in Vitamin E Status

Patrick Borel , Charles Desmarchelier
International Journal of Molecular Sciences, 2016, 17 (12), pp.E2094. ⟨10.3390/ijms17122094⟩
Journal articles inserm-01761218v1
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Can Genetic Variability in α-Tocopherol Bioavailability Explain the Heterogeneous Response to α-Tocopherol Supplements?

Patrick Borel , Charles Desmarchelier , Marion Nowicki , Romain Bott , Franck Tourniaire
Antioxidants and Redox Signaling, 2015, 22 (8), pp.669 - 678. ⟨10.1089/ars.2014.6144⟩
Journal articles inserm-01478428v1
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Lycopene bioavailability is associated with a combination of genetic variants

Patrick Borel , Charles Desmarchelier , Marion Nowicki , Romain Bott
Free Radical Biology and Medicine, 2015, 83, pp.238 - 244. ⟨10.1016/j.freeradbiomed.2015.02.033⟩
Journal articles inserm-01478367v1
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The Postprandial Chylomicron Triacylglycerol Response to Dietary Fat in Healthy Male Adults Is Significantly Explained by a Combination of Single Nucleotide Polymorphisms in Genes Involved in Triacylglycerol Metabolism

Charles Desmarchelier , Jean-Charles Martin , Richard Planells , Marguerite Gastaldi , Marion Nowicki
Journal of Clinical Endocrinology and Metabolism, 2014, 99 (3), pp.E484 - E488. ⟨10.1210/jc.2013-3962⟩
Journal articles inserm-01478528v1

ABCG1 is involved in vitamin E efflux

Maryline Olivier , Romain Bott , Eric Frisdal , Marion Nowicki , Wanee Plengpanich
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2014, 1841 (12), pp.1741 - 1751. ⟨10.1016/j.bbalip.2014.10.003⟩
Journal articles inserm-01478571v1

Genetic variants involved in interindividual variability in vitamin E bioavailability: towards a better understanding of the role of vitamin E in the aetiology of cardiovascular diseases

Charles Desmarchelier , Franck Tourniaire , Marion Nowicki , Romain Bott , Patrick Borel
European Heart Journal, 2014, 35 (supplément 1), pp.400
Journal articles hal-02629437v1

Variation in cholesterol absorption in healthy male adults can be explained by a combination of snps in cholesterol metabolism genes

Charles Desmarchelier , Estelle Wolff , Marion Nowicki , Alain Nicolay , Denis Lairon
Atherosclerosis, 2014, 235 (2), pp.E30. ⟨10.1016/j.atherosclerosis.2014.05.057⟩
Journal articles hal-02630615v1

Intestinal microbiota in metabolic diseases: from bacterial community structure and functions to species of pathophysiological relevance

Thomas Clavel , Charles Desmarchelier , Dirk Haller , Philippe Gerard , Sascha Rohn
Gut microbes, 2014, 5 (4), pp.544-551. ⟨10.4161/gmic.29331⟩
Journal articles hal-01608260v1

High-fat diet alters gut microbiota physiology in mice

Hannelore Daniel , Amin Moghaddas Gholami , David Berry , Charles Desmarchelier , Hannes Hahne
The International Society of Microbiologial Ecology Journal, 2014, 8 (2), pp.295 - 308. ⟨10.1038/ismej.2013.155⟩
Journal articles hal-01204436v1

The distribution and relative hydrolysis of tocopheryl acetate in the different matrices coexisting in the lumen of the small intestine during digestion could explain its low bioavailability

Charles Desmarchelier , Franck Tourniaire , Damien P. Prévéraud , Coralie Samson-Kremser , Isabelle Crenon
Molecular Nutrition and Food Research, 2013, 57 (7), pp.1237 - 1245. ⟨10.1002/mnfr.201200720⟩
Journal articles inserm-01478557v1
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Bioavailability of vitamin E in humans: an update

Patrick Borel , Damien Preveraud , Charles Desmarchelier
Nutrition Reviews, 2013, 71 (6), pp.319 - 331. ⟨10.1111/nure.12026⟩
Journal articles inserm-01478535v1

C-13 beta-Carotene stability during digestion in healthy humans

Rachel Kopec , Catherine Veyrat , Marion Nowicki , Beatrice Gleize , Charles Desmarchelier
Annual Meeting of the American-Society-for-Pharmacology-and-Experimental-Therapeutics (ASPET) at Experimental Biology Meeting, Apr 2017, Chicago, United States. pp.1
Conference papers hal-01605682v1

ABCB1 is involved in vitamin D intestinal efflux

Marielle Margier , Charles Desmarchelier , Alice Bluteau , André Collet , Patrick Borel
16. Fat Soluble Vitamins (FSV) congress, Société Française des Vitamines et Biofacteurs (SFVB). FRA., Mar 2017, Paris, France. 130 p
Conference papers hal-01517923v1

A Combination of Single-Nucleotide Polymorphisms Is Associated with the Interindividual Variability in Vitamin D Bioavailability in Healthy Men.

Charles Desmarchelier , Emmanuelle Reboul , Aurélie Goncalves , Rachel Kopec , Marion Nowicki
16. Fat Soluble Vitamins (FSV) congress, Société Française des Vitamines et Biofacteurs (SFVB). FRA., Mar 2017, Paris, France. 130 p
Conference papers hal-01517924v1
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Cholecalciferol (vitamin D3) and retinyl palmitate (vitamin A) display different solubilization capacities in mixed micelle solutions: effect of interactions with mixed micelle components and of cholecalciferol self-associating properties.

Damien P. Prévéraud , Charles Desmarchelier , David Chapron , Ali Makky , Véronique Rosilio
16. Fat Soluble Vitamins Congress - March 21-23, 2017 - Paris, Société Française des Vitamines et Biofacteurs (SFVB). FRA., Mar 2017, Paris, France. 130 p
Conference papers hal-01595512v1

Bioaccessibility and intestinal cellular uptake could partly explain relative biopotency of D3 vitamers.

Damien Preveraud , Charles Desmarchelier , Véronique Rosilio , Patrick Borel
4. international vitamin conference, May 2016, Copenhague, Denmark
Conference papers hal-01595223v1
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Retinyl esters and cholecalciferol interact for their incorporation into mixed micelles

Charles Desmarchelier , Ali Makky , David Chapron , Damien Preveraud , Véronique Rosilio
Satellite Meeting EuroMedLab « state of the art in the biology of trace elements and vitamins », Société Française de Biologie Clinique (SFBC). FRA., Jun 2015, Paris, France
Conference papers hal-01594761v1

The interindividual variability in vitamin e bioavailability in healthy male adults is significantly explained by a combination of SNPS in genes involved in vitamin e metabolism

Charles Desmarchelier , Franck Tourniaire , Marion Nowicki , Romain Bott , Patrick Borel
83. Congress of the European-Atherosclerosis-Society (EAS), European Atherosclerosis Society. Göteborg, SWE., Mar 2015, Glasgow, United Kingdom. 2 p
Conference papers hal-02738550v1

Une combinaison de polymorphismes mononucléotidiques est associée à la variabilité interindividuelle de la biodisponibilité du β-carotène chez des hommes sains.

Charles Desmarchelier , Marion Nowicki , Romain Bott , Patrick Borel
Journées francophones de nutrition, Société Française de Nutrition (SFN). FRA. Société Francophone Nutrition Clinique et Métabolisme (SFNEP), FRA., Dec 2015, Marseille, France. 320 p
Conference papers hal-01594763v1

How does vitamin E intake correlate with concentrations of tocopherols and their metabolites? Genetic variants involved in interindividual variability in vitamin E bioavailability

Charles Desmarchelier , Franck Tourniaire , Marion Nowicki , Romain Bott , Patrick Borel
SFRR Europe and the Society of Nutrition and Food Science (SNFS), European Crohn´s and Colitis Organisation (ECCO). INT., Sep 2015, Stuttgart, Germany. 1 p., ⟨10.1016/j.freeradbiomed.2015.07.066⟩
Conference papers hal-02741254v1
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Influence of the type of triacylglycerol fatty acids on vitamin E bioavailability: pig data and intestinal mechanisms involved.

Damien P. Prévéraud , Estelle Devillard , Patrick Borel , Charles Desmarchelier
13. Euro Fed Lipid Congress "Fats, Oils and Lipids: New challenges in technology, quality control and health", Sep 2015, Florence, Italy
Conference papers hal-01595484v1
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SNPs involved in interindividual variability in chylomicron triacylglycerol response to dietary fat play a significant role in interindividual variability in chylomicron lutein response to dietary lutein.

Patrick Borel , Charles Desmarchelier , Marion Nowicki , Romain Bott
17. International Symposium on Carotenoids, International Carotenoid Society (ICS). USA., Jun 2014, Utah, United States
Conference papers hal-01594696v1
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A combination of SNPS is associated with the postprandial chylomicron triacylglycerol response in healthy male adults

Charles Desmarchelier , Jean-Charles Martin , Richard Planells , Marguerite Gastaldi , Marion Nowicki
10. International Congress on Coronary Artery Disease, Oct 2013, Florence, Italy
Conference papers hal-02749985v1
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Genetic determinants of vitamin E status

Patrick Borel , Charles Desmarchelier
Principles of nutrigenetics and nutrigenomics, Academic Press - Elsevier, pp.255-261, 2020, ⟨10.1016/B978-0-12-804572-5.00033-1⟩
Book sections hal-01605809v1
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Tomatoes and lycopene : inflammatory modulator effects

Jean-Francois Landrier , Franck Tourniaire , Soumaya Fenni , Charles Desmarchelier , Patrick Borel
Tomatoes and lycopene in human nutrition and health, preventing chronic diseases, CRC Press, Boca Raton. Florida (USA), 2017
Book sections hal-01605211v1
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Bioavailability of vitamin E in humans

Charles Desmarchelier , Patrick Borel
Bioavailability of vitamin E in humans, ELSEVIER SCIENCE, 2017, Physiology of the gastrointestinal tract (sixth edition)
Book sections hal-01605205v1
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Genetic polymorphisms associated with blood concentration of lycopene

Patrick Borel , Jean-Francois Landrier , Charles Desmarchelier
Tomatoes and lycopene in human nutrition and health, preventing chronic diseases, CRC Press, 2017
Book sections hal-01603161v1