Christophe Arpin

46
Documents
Affiliation actuelle
  • Centre International de Recherche en Infectiologie (CIRI)

Présentation

Domaines de recherche

Immunité adaptative Vaccinologie Bio-Informatique, Biologie Systémique [q-bio.QM]

Publications

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Publications

Image document

Exogenous IL-2 delays memory precursors generation and is essential for enhancing memory cells effector functions

Shaoying Wang , Margaux Prieux , Simon de Bernard , Maxence Dubois , Daphne Laubreton et al.
iScience, 2024, 27 (4), pp.109411. ⟨10.1016/j.isci.2024.109411⟩
Article dans une revue hal-04598215 v1
Image document

In silico modelling of CD8 T cell immune response links genetic regulation to population dynamics

Thi Nhu Thao Nguyen , Madge Martin , C Arpin , Samuel Bernard , Olivier Gandrillon et al.
ImmunoInformatics, 2024, 15, pp.100043. ⟨10.1016/j.immuno.2024.100043⟩
Article dans une revue hal-04489553 v2
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In silico single-cell metabolism analysis unravels a new transition stage of CD8 T cells 4 days post-infection

Christophe Arpin , Franck Picard , Olivier Gandrillon
ImmunoInformatics, 2023, 14, pp.100038. ⟨10.1101/2023.09.22.558248⟩
Article dans une revue hal-04566377 v1
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scAN1.0: A reproducible and standardized pipeline for processing 10X single cell RNAseq data

Maxime Lepetit , Mirela Diana Ilie , Marie Chanal , Gérald Raverot , Philippe Bertolino et al.
In Silico Biology, 2023, 15, pp.11 - 21. ⟨10.3233/isb-220252⟩
Article dans une revue hal-04305326 v1
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CD8 memory precursor cell generation is a continuous process

Helena Todorov , Margaux Prieux , Daphne Laubreton , Matteo Bouvier , Shaoying Wang et al.
iScience, 2022, 25 (9), pp.104927. ⟨10.1016/j.isci.2022.104927⟩
Article dans une revue hal-03842898 v1
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Modeling and characterization of inter-individual variability in CD8 T cell responses in mice

Chloe Audebert , Daphné Laubreton , Christophe Arpin , Olivier Gandrillon , Jacqueline Marvel et al.
In Silico Biology, 2021, 14 (1-2), pp.13-39. ⟨10.3233/ISB-200205⟩
Article dans une revue hal-03136073 v1
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Model-based assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-cell Immune Responses

Simon Girel , Christophe Arpin , Jacqueline Marvel , Olivier Gandrillon , Fabien Crauste
Frontiers in Immunology, In press, pp.1-41. ⟨10.3389/fimmu.2019.00230⟩
Article dans une revue hal-02008705 v1

Identification of Nascent Memory CD8 T Cells and Modeling of Their Ontogeny

Fabien Crauste , Julien Mafille , Lilia Boucinha , Sophia Djebali , Olivier Gandrillon et al.
Cell Systems, 2017, 4 (3), pp.306-317. ⟨10.1016/j.cels.2017.01.014⟩
Article dans une revue hal-01409637 v1
Image document

IL-2 sensitivity and exogenous IL-2 concentration gradient tune the productive contact duration of CD8+ T cell-APC: a multiscale modeling study

Xuefeng Gao , Christophe Arpin , Jacqueline Marvel , Sotiris A. Prokopiou , Olivier Gandrillon et al.
BMC Systems Biology, 2016, 10 (1), pp.77. ⟨10.1186/s12918-016-0323-y⟩
Article dans une revue inserm-01354185 v1
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Immune signatures of protective spleen memory CD8 T cells

Lilia Brinza , Sophia Djebali , Martine Tomkowiak , Julien Mafille , Céline Loiseau et al.
Scientific Reports, 2016, 6, pp.37651. ⟨10.1038/srep37651⟩
Article dans une revue hal-01911427 v1
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Predicting pathogen-specific CD8 T cell immune responses from a modeling approach.

Fabien Crauste , Emmanuelle Terry , I Le Mercier , Julien Mafille , Sophie Djebali et al.
Journal of Theoretical Biology, 2015, 374, pp.66-82. ⟨10.1016/j.jtbi.2015.03.033⟩
Article dans une revue hal-00717406 v2

Multiscale Modeling of the Early CD8 T-Cell Immune Response in Lymph Nodes: An Integrative Study

Sotiris Prokopiou , Loic Barbarroux , Samuel Bernard , Julien Mafille , Yann Leverrier et al.
Computation, 2014, 2 (4), pp.159-181. ⟨10.3390/computation2040159⟩
Article dans une revue hal-01074736 v1

Mathematical model of the primary CD8 T cell immune response: stability analysis of a nonlinear age-structured system.

Emmanuelle Terry , Jacqueline Marvel , Christophe Arpin , Olivier Gandrillon , Fabien Crauste
Journal of Mathematical Biology, 2012, 65, pp.263-291. ⟨10.1007/s00285-011-0459-8⟩
Article dans une revue istex hal-00649219 v1

T inflammatory memory CD8 T cells participate to antiviral response and generate secondary memory cells with an advantage in XCL1 production

Virginie Jubin , Erwan Ventre , Yann Leverrier , Sophia Djebali , Katia Mayol et al.
Immunologic Research, 2012, 52 (3), pp.284-293. ⟨10.1007/s12026-012-8340-4⟩
Article dans une revue istex hal-02474056 v1

TLR2 engagement on memory CD8 + T cells improves their cytokine-mediated proliferation and IFN-γ secretion in the absence of Ag

Anne Cottalorda , Blandine C. Mercier , Florentin Mbitikon-Kobo , Christophe Arpin , Denise Teoh et al.
European Journal of Immunology, 2009, 39 (10), pp.2673-2681. ⟨10.1002/eji.200939627⟩
Article dans une revue hal-02474074 v1

Nationwide survey of extended-spectrum {beta}-lactamase-producing Enterobacteriaceae in the French community setting.

C. Arpin , C. Quentin , F. Grobost , E. Cambau , J. Robert et al.
Journal of Antimicrobial Chemotherapy, 2009, 63 (6), pp.1205-14. ⟨10.1093/jac/dkp108⟩
Article dans une revue istex hal-00426312 v1

Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions.

Florentin Martial Mbitikon-Kobo , Marc Vocanson , Marie-Cécile Michallet , Martine Tomkowiak , Anne Cottalorda et al.
Journal of Immunology, 2009, 182 (6), pp.3846-54. ⟨10.4049/jimmunol.0802438⟩
Article dans une revue inserm-00392005 v1

Loss of p53 or p73 in human papillomavirus type 38 E6 and E7 transgenic mice partially restores the UV-activated cell cycle checkpoints

W Dong , Christophe Arpin , R Accardi , L Gissmann , B Sylla et al.
Oncogene, 2008, 27 (20), pp.2923-2928. ⟨10.1038/sj.onc.1210944⟩
Article dans une revue hal-02474213 v1

Synthesis of omeprazole analogues and evaluation of these as potential inhibitors of the multidrug efflux pump NorA of Staphylococcus aureus.

C; Vidaillac , J. Guillon , C. Arpin , I. Forfar-Bares , B. B. Ba et al.
Antimicrobial Agents and Chemotherapy, 2007, 51 (3), pp.831-8. ⟨10.1128/AAC.01306-05⟩
Article dans une revue hal-00166189 v1

High genetic stability of integrons in clinical isolates of Shigella spp. of worldwide origin.

V. Dubois , M. P. Parizano , C. Arpin , L. Coulange , M. C. Bezian et al.
Antimicrobial Agents and Chemotherapy, 2007, 51 (4), pp.1333-40. ⟨10.1128/AAC.01109-06⟩
Article dans une revue hal-00166190 v1

Extended-Spectrum {beta}-Lactamase-producing Enterobacteriaceae in Various Types of Private Health Care Centers.

C. Arpin , L. Coulange , V. Dubois , C. André , I. Fischer et al.
Antimicrobial Agents and Chemotherapy, 2007, Sous presse. ⟨10.1128/AAC.01431-06⟩
Article dans une revue hal-00166193 v1

Hyperproliferative Response of a Monoclonal Memory CD8 T Cell Population Is Characterized by an Increased Frequency of Clonogenic Precursors

Christophe Arpin , Georgi S. Angelov , Thierry Walzer , Martine Tomkowiak , Laurent Belœil et al.
Journal of Immunology, 2002, 168 (5), pp.2147-2153. ⟨10.4049/jimmunol.168.5.2147⟩
Article dans une revue hal-02474116 v1

Differential In Vivo Persistence of Two Subsets of Memory Phenotype CD8 T Cells Defined by CD44 and CD122 Expression Levels

Thierry Walzer , Christophe Arpin , Laurent Beloeil , Jacqueline Marvel
Journal of Immunology, 2002, 168 (6), pp.2704-2711. ⟨10.4049/jimmunol.168.6.2704⟩
Article dans une revue hal-02474128 v1

Evolution of genome size in Drosophila. is the invader`s genome being invaded by transposable elements?

Cristina Vieira , C. Nardon , C. Arpin , D. Lepetit , C. Biémont
Molecular Biology and Evolution, 2002, 19, pp.1154-1161
Article dans une revue hal-00427308 v1

Type II topoisomerase quinolone resistance-determining regions of Aeromonas caviae, A. hydrophila, and A. sobria complexes and mutations associated with quinolone resistance

Marisol Goñi , C. Arpin , M. Capdepuy , V. Dubois , Pierre Caumette et al.
Antimicrobial Agents and Chemotherapy, 2002, 46 (2), pp.350-359. ⟨10.1128/AAC.46.2.350-359.2002⟩
Article dans une revue hal-01631903 v1

Involvement of inhibitory NKRs in the survival of a subset of memory-phenotype CD8+ T cells

Sophie Ugolini , Christophe Arpin , Nicolas Anfossi , Thierry Walzer , Anna Cambiaggi et al.
Nature Immunology, 2001, 2 (5), pp.430-435. ⟨10.1038/87740⟩
Article dans une revue hal-02474146 v1

Effects of T3Ralpha1 and T3Ralpha2 gene deletion on T and B lymphocyte development.

C. Arpin , M. Philgren , A. Fraichard , Denise Aubert , Jacques Samarut et al.
Journal of Immunology, 2000, 164, pp.152-160
Article dans une revue hal-00023804 v1

Effects of T3R alpha 1 and T3R alpha 2 gene deletion on T and B lymphocyte development

C. Arpin , M. Philgren , A. Fraichard , Denise Aubert , Jacques Samarut et al.
Journal of Immunology, 2000, 164, pp.152-160
Article dans une revue hal-02685706 v1

Effects of T3Rα1 and T3Rα2 Gene Deletion on T and B Lymphocyte Development

Christophe Arpin , Maria Pihlgren , Alexandre Fraichard , Denise Aubert , Jacques Samarut et al.
Journal of Immunology, 2000, 164 (1), pp.152-160. ⟨10.4049/jimmunol.164.1.152⟩
Article dans une revue hal-03634583 v1

Characterization at the Single-Cell Level of Naive and Primed CD8 T Cell Cytokine Responses

Thierry Walzer , Patrice Dubois , Martine Tomkowiak , Christophe Arpin , Maria Pihlgren et al.
Cellular Immunology, 2000, 206 (1), pp.16-25. ⟨10.1006/cimm.2000.1720⟩
Article dans une revue istex hal-02474152 v1

Impact of an urban effluent on antibiotic resistance of riverine Enterobacteriaceae and Aeromonas spp.

Marisol Goñi , M. Capdepuy , C. Arpin , N. Raymond , Pierre Caumette et al.
Applied and Environmental Microbiology, 2000, 66 (1), pp.125-132. ⟨10.1128/AEM.66.1.125-132.2000⟩
Article dans une revue hal-01631904 v1

Memory CD44int CD8 T cells show increased proliferative responses and IFN-γ production following antigenic challenge in vitro

Maria Pihlgren , Christophe Arpin , Thierry Walzer , Martine Tomkowiak , Annie Thomas et al.
International Immunology, 1999, 11 (5), pp.699-706. ⟨10.1093/intimm/11.5.699⟩
Article dans une revue hal-02474162 v1

Dendritic Cells Enhance the Differentiation of Naive B Cells into Plasma Cells In Vitro

Jérôme Fayette , Isabelle Durand , Jean-Michel Bridon , Christophe Arpin , Bertrand Dubois et al.
Scandinavian Journal of Immunology, 1998, 48 (6), pp.563-570. ⟨10.1046/j.1365-3083.1998.00471.x⟩
Article dans une revue hal-02474199 v1

The Normal Counterpart of IgD Myeloma Cells in Germinal Center Displays Extensively Mutated IgVH Gene, Cμ–Cδ Switch, and λ Light Chain Expression

Christophe Arpin , Odette de Bouteiller , Diane Razanajaona , Isabelle Fugier-Vivier , Francine Brière et al.
Journal of Experimental Medicine, 1998, 187 (8), pp.1169-1178. ⟨10.1084/jem.187.8.1169⟩
Article dans une revue hal-02474169 v1

Positive and Negative Selection of Human B Lymphocytes in Vitro

Jacques Banchereau , Laurent Galibert , Christophe Arpin , Nicolas Burdin , Yong-Jun Liu et al.
Annals of the New York Academy of Sciences, 1997, 815 (1 B-Lymphocytes), pp.237-245. ⟨10.1111/j.1749-6632.1997.tb52065.x⟩
Article dans une revue istex hal-02474241 v1

Memory B Cells Are Biased Towards Terminal Differentiation: A Strategy That May Prevent Repertoire Freezing

Christophe Arpin , Jacques Banchereau , Yong-Jun Liu
Journal of Experimental Medicine, 1997, 186 (6), pp.931-940. ⟨10.1084/jem.186.6.931⟩
Article dans une revue hal-02474219 v1

Germinal center development

Yong-Jun Liu , Christophe Arpin
Immunological Reviews, 1997, 156 (1), pp.111-126. ⟨10.1111/j.1600-065x.1997.tb00963.x⟩
Article dans une revue istex hal-02474229 v1

Germinal Center Founder Cells Display Propensity for Apoptosis before Onset of Somatic Mutation

Serge Lebecque , Odette de Bouteiller , Christophe Arpin , Jacques Banchereau , Yong-Jun Liu
Journal of Experimental Medicine, 1997, 185 (3), pp.563-572. ⟨10.1084/jem.185.3.563⟩
Article dans une revue hal-02474258 v1

Human Peripheral B Cell Development sIgM - IgD + CD38 + Hypermutated Germinal Center Centroblasts Preferentially Express Iglambda Light Chain and Have Undergone Cmu-to-Cdelta Switch

Christophe Arpin , Odette de Bouteiller , Diane Razanajaona , Francine Brière , Jacques Banchereau et al.
Annals of the New York Academy of Sciences, 1997, 815 (1 B-Lymphocytes), pp.193-196. ⟨10.1111/j.1749-6632.1997.tb52060.x⟩
Article dans une revue istex hal-02474251 v1

Sequential triggering of apoptosis, somatic mutation and isotype switch during germinal center development

Yong-Jun Liu , Christophe Arpin , Odette de Bouteiller , Christiane Guret , Jacques Banchereau et al.
Seminars in Immunology, 1996, 8 (3), pp.169-177. ⟨10.1006/smim.1996.0021⟩
Article dans une revue istex hal-02474265 v1

Normal Human IgD+IgM− Germinal Center B Cells Can Express Up to 80 Mutations in the Variable Region of Their IgD Transcripts

Yong-Jun Liu , Odette de Bouteiller , Christophe Arpin , Francine Brière , Laurent Galibert et al.
Immunity, 1996, 4 (6), pp.603-613. ⟨10.1016/s1074-7613(00)80486-0⟩
Article dans une revue hal-02474288 v1

Generation of memory B cells and plasma cells in vitro

Christophe Arpin , J. Dechanet , C. van Kooten , P. Merville , G. Grouard et al.
Science, 1995, 268 (5211), pp.720-722. ⟨10.1126/science.7537388⟩
Article dans une revue hal-02474293 v1

Memory B cells from human tonsils colonize mucosal epithelium and directly present antigen to T cells by Rapid Up-Regulation of B7-1 and B7-2

Yong-Jun Liu , Clarisse Barthélémy , Odette De Bouteiller , Christophe Arpin , Isabelle Durand et al.
Immunity, 1995, 2 (3), pp.239-248. ⟨10.1016/1074-7613(95)90048-9⟩
Article dans une revue hal-02474297 v1

Five Human Mature B Cell Subsets

Yong-Jun Liu , Odette de Bouteiller , Christophe Arpin , Isabelle Durand , Jacques Banchereau
In Vivo Immunology: Regulatory processes during lymphopoiesis and immunopoiesis, pp.289-294, 1994
Chapitre d'ouvrage hal-02238859 v1

Pectinolysis regulation in Erwinia chrysanthemi

Sylvie Reverchon , Nicole Hugouvieux-Cotte-Pattat , Guy Condemine , C. Bourson , Christophe Arpin et al.
Plant Pathogenic Bacteria, Akademiai Kiado publishers, pp.739-744, 1990
Chapitre d'ouvrage hal-01979402 v1