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Les Journées de recherche respiratoires 2025 : une première à Caen !
Isabella Annesi-Maesano
,
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Grégory Bouchaud
,
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Pierre Gosset
et al.
Article dans une revue
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Inactivation of the Phosphatase Activity of Soluble Epoxide Hydrolase Modulates SIRT3 and Attenuates Experimental Pulmonary Hypertension
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Mustapha Chelgham
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Ly Tu
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Severine Ménoret
et al.
Article dans une revue
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Bone Morphogenetic Protein-9 Controls Pulmonary Vascular Growth and Remodeling
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Fabien Robert
et al.
Article dans une revue
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Evolving paradigms in pulmonary hypertension: Highlights of the 6th French Pulmonary Hypertension Network Meeting
Athénaïs Boucly
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Antoine Beauvais
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Thomas Lacoste-Palasset
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Mitja Jevnikar
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Marianne Riou
et al.
Article dans une revue
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On your marks, get set, go for the 20th edition of J2R 2024 in Paris!
I. Annesi-Maesano
,
P. Bonniaud
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G. Bouchaud
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L. Boyer
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P. Gosset
et al.
Article dans une revue
hal-04989188v1
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Placental growth factor modulates endothelial NO production and exacerbates experimental hepatopulmonary syndrome
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Feriel Benchenouf
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My Ngoc Ha
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Alessandra Cuomo
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Mina Ottaviani
et al.
Article dans une revue
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Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome
Fabien Robert
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Marie-Caroline Certain
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Audrey Baron
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Raphaël Thuillet
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Léa Duhaut
et al.
Article dans une revue
hal-05202933v1
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Retour triomphant des J2R 2023 à Tours : un tourbillon d’échanges scientifiques et d’émotion
I. Annesi-Maesano
,
Philippe Bonniaud
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G. Bouchaud
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L. Boyer
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Sylvie Gazzeri
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Article dans une revue
hal-04550861v1
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Pulmonary vascular phenotype identified in patients with GDF2 ( BMP9 ) or BMP10 variants: an international multicentre study
Julien Grynblat
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Harm Jan Bogaard
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Mélanie Eyries
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Olivier Meyrignac
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Laurent Savale
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Article dans une revue
hal-04651213v1
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Impact of heterozygous ALK1 mutations on the transcriptomic response to BMP9 and BMP10 in endothelial cells from hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension donors
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H. Liu
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D. Koça
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M. Al Tarrass
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L. Tu
et al.
Article dans une revue
hal-04478405v1
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Disrupted BMP-9 Signaling Impairs Pulmonary Vascular Integrity in Hepatopulmonary Syndrome
Fabien Robert
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Marie-Caroline Certain
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Audrey Baron
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Raphaël Thuillet
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Léa Duhaut
et al.
Article dans une revue
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Role of KCNK3 Dysfunction in Dasatinib-associated Pulmonary Arterial Hypertension and Endothelial Cell Dysfunction
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Anaïs Saint-Martin Willer
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Benoit Chevalier
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Maria Sancho
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Bastien Masson
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Article dans une revue
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Exploring the Endothelin-1 pathway in chronic thromboembolic pulmonary hypertension microvasculopathy
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Cuomo Alessandra
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Gorth Deborah
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Normand Corinne
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Thuillet Raphaël
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Article dans une revue
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Evidence and unresolved questions in pulmonary hypertension: Insights from the 5th French Pulmonary Hypertension Network Meeting
Athénaïs Boucly
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Laurent Bertoletti
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Charles Fauvel
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Mélanie Gallant Dewavrin
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Christian Gerges
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Article dans une revue
hal-04953892v1
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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury
Matthieu Leuillier
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Thomas Duflot
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Séverine Ménoret
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Hind Messaoudi
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Zoubir Djerada
et al.
Article dans une revue
hal-03836917v1
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AMPK activation by metformin protects against pulmonary hypertension in rats and relaxes isolated human pulmonary artery
Heba Abdelazeem
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Ly Tu
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Raphaël Thuillet
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Mina Ottaviani
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Achraf Boulfrad
et al.
Article dans une revue
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Endothelial cells in pulmonary fibrosis: more than a bystander
Toyoshi Yanagihara
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Christophe Guignabert
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Martin R.J. Kolb
Article dans une revue
hal-04532858v1
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Arsenic trioxide demonstrates efficacy in a mouse model of preclinical systemic sclerosis
Anne Cauvet
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Arthur Decellas
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Christophe Guignabert
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Dominique Rongvaux-Gaïda
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Raphaël Thuillet
et al.
Article dans une revue
hal-04763926v1
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Inhibition of Soluble Epoxide Hydrolase Does Not Promote or Aggravate Pulmonary Hypertension in Rats
Matthieu Leuillier
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Valentin Platel
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Ly Tu
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Guillaume Feugray
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Raphaël Thuillet
et al.
Article dans une revue
hal-04532894v1
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Dysfonction de la signalisation endothéliale du BMP-9 dans les maladies vasculaires pulmonaires
F. Robert
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N. Berrebeh
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C. Guignabert
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M. Humbert
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S. Bailly
et al.
Article dans une revue
hal-04532908v1
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Biomarkers of haemodynamic severity of systemic sclerosis-associated pulmonary arterial hypertension by serum proteome analysis
Sébastien Sanges
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Lisa Rice
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Ly Tu
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Eleanor Valenzi
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Jean-Luc Cracowski
et al.
Article dans une revue
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The central role of ubiquitin-specific protease 8 in leptin signaling pathway in pulmonary arterial hypertension
Etienne-Marie Jutant
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Mustapha K Chelgham
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Mina Ottaviani
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Raphaël Thuillet
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Benjamin Le Vely
et al.
Article dans une revue
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Serum and Pulmonary Expression Profiles of the Activin Signaling System in Pulmonary Arterial Hypertension
Christophe Guignabert
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Laurent Savale
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Athénaïs Boucly
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Raphaël Thuillet
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Ly Tu
et al.
Article dans une revue
hal-04092113v1
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Effects of B Cell Depletion by CD19‐Targeted Chimeric Antigen Receptor T Cells in a Murine Model of Systemic Sclerosis
Jérôme Avouac
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Cindy Orvain
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Morgane Boulch
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Françoise Tilotta
et al.
Article dans une revue
hal-04763928v1
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Arsenic trioxide demonstrates efficacy in a mouse model of preclinical systemic sclerosis
Anne Cauvet
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Arthur Decellas
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Christophe Guignabert
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Dominique Rongvaux-Gaïda
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Raphaël Thuillet
et al.
Article dans une revue
hal-04525616v1
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Treatment of pulmonary arterial hypertension: recent progress and a look to the future
Marc Humbert
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Olivier Sitbon
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Christophe Guignabert
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Laurent Savale
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Athénaïs Boucly
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Article dans une revue
hal-04532955v1
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Syndrome hépatopulmonaire : prévalence, physiopathologie et implications cliniques
M.-C. Certain
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F. Robert
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A. Baron
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O. Sitbon
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M. Humbert
et al.
Article dans une revue
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Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Rα
Zongye Cai
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Siyu Tian
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Theo Klein
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Ly Tu
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Laurie Geenen
et al.
Article dans une revue
hal-04532809v1
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Phenotypic Diversity of Vascular Smooth Muscle Cells in Pulmonary Arterial Hypertension
Benoit Lechartier
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Nihel Berrebeh
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Alice Huertas
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Marc Humbert
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Christophe Guignabert
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Article dans une revue
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RESPIRenT : RESeau de Pneumologie en Innovation et Recherche translaTionnelle, un nouveau souffle pour les J2R
Isabella Annesi‐maesano
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P. Bonniaud
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G. Bouchaud
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L. Boyer
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S. Gazzeri
et al.
Article dans une revue
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New Mutations and Pathogenesis of Pulmonary Hypertension: Progress and Puzzles in Disease Pathogenesis
Micheala Aldred
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Nicholas Morrell
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Christophe Guignabert
Article dans une revue
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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells
Benjamin Le Vely
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Carole Phan
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Nihel Berrebeh
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Raphaël Thuillet
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Mina Ottaviani
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Article dans une revue
inserm-03678207v1
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Loss of cAbl Tyrosine Kinase in Pulmonary Arterial Hypertension Causes Dysfunction of Vascular Endothelial Cells
Benjamin Le Vely
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Carole Phan
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Raphaël Thuillet
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Mina Ottaviani
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Article dans une revue
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Chronic thromboembolic pulmonary hypertension: the magic of pathophysiology
Gérald Simonneau
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Peter Dorfmüller
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Christophe Guignabert
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Olaf Mercier
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Marc Humbert
Article dans une revue
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Driving Role of Interleukin‐2–Related Regulatory CD4 + T Cell Deficiency in the Development of Lung Fibrosis and Vascular Remodeling in a Mouse Model of Systemic Sclerosis
Camelia Frantz
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Anne Cauvet
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Aurélie Durand
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Virginie Gonzalez
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Rémi Pierre
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Article dans une revue
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Mineralocorticoid Receptor Antagonism by Finerenone Attenuates Established Pulmonary Hypertension in Rats.
Ly Tu
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Raphaël Thuillet
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Julie Perrot
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Emy Ponsardin
et al.
Article dans une revue
inserm-03755156v1
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Driving Role of Interleukin‐2–Related Regulatory CD4 + T Cell Deficiency in the Development of Lung Fibrosis and Vascular Remodeling in a Mouse Model of Systemic Sclerosis
Camelia Frantz
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Anne Cauvet
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Aurélie Durand
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Virginie Gonzalez
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Rémi Pierre
et al.
Article dans une revue
hal-03985019v1
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Loss of lung microvascular endothelial Piezo2 expression impairs NO synthesis, induces EndMT, and is associated with pulmonary hypertension
Siyu Tian
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Zongye Cai
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Payel Sen
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Denise van Uden
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Esther van de Kamp
et al.
Article dans une revue
inserm-04270340v1
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Erythrocytes are altered in pulmonary arterial hypertension
Etienne-Marie Jutant
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Ly Tu
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Raphaël Thuillet
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Véronique Picard
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Christophe Guignabert
et al.
Article dans une revue
hal-04532754v1
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Platelet‐Derived Growth Factor Receptor Type α Activation Drives Pulmonary Vascular Remodeling Via Progenitor Cell Proliferation and Induces Pulmonary Hypertension
Julien Solinc
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Jessica Raimbault‐machado
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France Dierick
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Lamiaa El Bernoussi
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Ly Tu
et al.
Article dans une revue
hal-03629264v1
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Smooth muscle Rac1 contributes to pulmonary hypertension
Florian Dilasser
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Marc Rio
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Lindsay Rose
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Angela Tesse
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Christophe Guignabert
et al.
Article dans une revue
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Identifying new drugs associated with pulmonary arterial hypertension: A WHO pharmacovigilance database disproportionality analysis
Alex Hlavaty
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Matthieu Roustit
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David Montani
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Marie‐camille Chaumais
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Christophe Guignabert
et al.
Article dans une revue
hal-04520451v1
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Cytokines as Prognostic Biomarkers in Pulmonary Arterial Hypertension
Athénaïs Boucly
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Ly Tu
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Christophe Guignabert
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Christopher Rhodes
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Pascal de Groote
et al.
Article dans une revue
hal-03911708v1
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Acazicolcept (ALPN-101), a dual ICOS/CD28 antagonist, demonstrates efficacy in systemic sclerosis preclinical mouse models
Cindy Orvain
,
Anne Cauvet
,
Alexis Prudent
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Christophe Guignabert
,
Raphaël Thuillet
et al.
Article dans une revue
hal-03844870v1
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IL ‐2‐related regulatory CD4 T‐cell deficiency leads to the development of lung fibrosis and vascular remodeling
Camelia Frantz
,
Anne Cauvet
,
Aurélie Durand
,
Virginie Gonzalez
,
Rémi Pierre
et al.
Article dans une revue
inserm-03652770v1
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Smooth muscle Rac1 contributes to pulmonary hypertension Short running title: Role of Rac1 in pulmonary hypertension
Florian Dilasser
,
Marc Rio
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Lindsay Rose
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Angela Tesse
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Christophe Guignabert
et al.
British Journal of Pharmacology, In press
Article dans une revue
hal-03582408v1
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Tonnerre de Brest ! Des Journées de Recherche Respiratoires 2020 pas comme les autres…
I. Annesi-Maesano
,
P. Bonniaud
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G. Bouchaud
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L. Boyer
,
N. Frossard
et al.
Article dans une revue
hal-03234846v1
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The multifaceted problem of pulmonary arterial hypertension in systemic sclerosis
Cosimo Bruni
,
Christophe Guignabert
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Mirko Manetti
,
Marco Matucci Cerinic
,
Marc Humbert
Article dans une revue
hal-04532101v1
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The Thousand Faces of Leptin in the Lung
Etienne-Marie Jutant
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Ly Tu
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Marc Humbert
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Christophe Guignabert
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Alice Huertas
Article dans une revue
hal-04526973v1
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Serum and Pulmonary Uric Acid in Pulmonary Arterial Hypertension
Laurent Savale
,
Satoshi Akagi
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Ly Tu
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Amélie Cumont
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Raphaël Thuillet
et al.
Article dans une revue
inserm-03118201v1
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Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention
Takayuki Jujo Sanada
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Xiao-Qing Sun
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Chris Happé
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Christophe Guignabert
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Ly Tu
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Article dans une revue
hal-04526974v1
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An endothelial activin A-bone morphogenetic protein receptor type 2 link is overdriven in pulmonary hypertension
Gusty Ryanto
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Koji Ikeda
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Kazuya Miyagawa
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Ly Tu
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Christophe Guignabert
et al.
Article dans une revue
hal-04532633v1
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Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10
Claire Bouvard
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Ly Tu
,
Martina Rossi
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Agnès Desroches-Castan
,
Nihel Berrebeh
et al.
Article dans une revue
hal-03264032v1
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Preventing the Increase in Lysophosphatidic Acids: A New Therapeutic Target in Pulmonary Hypertension?
Thomas Duflot
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Ly Tu
,
Matthieu Leuillier
,
Hind Messaoudi
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Déborah Groussard
et al.
Article dans une revue
hal-04532610v1
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Cibler les ligands du récepteur de l’activine de type IIA pour traiter l’hypertension artérielle pulmonaire
Marc Humbert
,
David Montani
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Laurent Savale
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Ly Tu
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Christophe Guignabert
Article dans une revue
hal-03379128v1
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The quiescent endothelium: signalling pathways regulating organ-specific endothelial normalcy
Nicolas Ricard
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Sabine Bailly
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Christophe Guignabert
,
Michael Simons
Article dans une revue
inserm-03153011v1
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Essential role of smooth muscle Rac1 in severe asthma-associated airway remodelling
Florian Dilasser
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Lindsay Rose
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Dorian Hassoun
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Martin Klein
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Morgane Rousselle
et al.
Article dans une revue
hal-03142499v2
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Screening for pulmonary arterial hypertension in adults carrying a BMPR2 mutation
David Montani
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Barbara Girerd
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Xavier Jaïs
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Pierantonio Laveneziana
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Edmund M.T. Lau
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Article dans une revue
hal-04007994v1
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Interplay of sex hormones and long-term right ventricular adaptation in a Dutch PAH-cohort
Jessie van Wezenbeek
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Joanne A Groeneveldt
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Aida Llucià-Valldeperas
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Cathelijne E van Der Bruggen
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Samara M A Jansen
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Article dans une revue
inserm-03558871v1
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Additive Protective Effects of Sacubitril/Valsartan and Bosentan on Vascular Remodeling in Experimental Pulmonary Hypertension
Marie-Camille Chaumais
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Mohamed Reda Amar Djessas
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Raphaël Thuillet
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Amélie Cumont
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Ly Tu
et al.
Article dans une revue
inserm-02907132v1
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Purinergic Dysfunction in Pulmonary Arterial Hypertension
Zongye Cai
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Ly Tu
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Christophe Guignabert
,
Daphne Merkus
,
Zhichao Zhou
Article dans une revue
hal-04526804v1
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Lower Plasma Melatonin Levels Predict Worse Long-Term Survival in Pulmonary Arterial Hypertension
Zongye Cai
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Theo Klein
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Laurie Geenen
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Ly Tu
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Siyu Tian
et al.
Article dans une revue
inserm-02581568v1
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Multiple roles of macrophage migration inhibitory factor in pulmonary hypertension
Gael Jalce
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Christophe Guignabert
Article dans une revue
inserm-02454988v1
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FRI0590 BIOMARKERS OF HEMODYNAMIC SEVERITY OF SYSTEMIC-SCLEROSIS ASSOCIATED PULMONARY ARTERIAL HYPERTENSION BY SERUM PROTEOME ANALYSIS
S. Sanges
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L. Rice
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L. Tu
,
J.L. Cracowski
,
D. Montani
et al.
Article dans une revue
hal-05130626v1
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Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease
Claire Bouvard
,
Nafiisha Genet
,
Carole Phan
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Baptiste Rode
,
Raphaël Thuillet
et al.
Article dans une revue
hal-04608766v1
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Targeting Transforming Growth Factor Beta Receptors in Pulmonary Hypertension
Christophe Guignabert
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Marc Humbert
Article dans une revue
inserm-02918857v1
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Dendritic Cells in Pulmonary Hypertension: Foot Soldiers or Hidden Enemies?
Christophe Guignabert
Article dans une revue
inserm-02918859v1
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Endothelial cell dysfunction: a major player in SARS-CoV-2 infection (COVID-19)?
Alice Huertas
,
David Montani
,
Laurent Savale
,
Jérémie Pichon
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Ly Tu
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Article dans une revue
hal-04526866v1
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Lineage Tracing Reveals the Dynamic Contribution of Pericytes to the Blood Vessel Remodeling in Pulmonary Hypertension
Jennifer Bordenave
,
Ly Tu
,
Nihel Berrebeh
,
Raphaël Thuillet
,
Amélie Cumont
et al.
Article dans une revue
inserm-02454982v2
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The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient
Chris Happé
,
Kondababu Kurakula
,
Xiao-Qing Sun
,
Denielli da Silva Goncalves Bos
,
Nina Rol
et al.
Article dans une revue
hal-04526850v1
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Pulmonary complications of Bcr-Abl tyrosine kinase inhibitors
Jason Weatherald
,
Louise Bondeelle
,
Marie-Camille Chaumais
,
Christophe Guignabert
,
Laurent Savale
et al.
Article dans une revue
hal-04526808v1
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Neutralization of CXCL12 attenuates established pulmonary hypertension in rats Short Title: CXCL12 neutraligands in severe PH in the rat
Jennifer Bordenave
,
Raphaël Thuillet
,
Ly Tu
,
Carole Phan
,
Amélie Cumont
et al.
Article dans une revue
hal-02195697v1
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Lysyl oxidase—a possible role in systemic sclerosis–associated pulmonary hypertension: a multicentre study
Zahava Vadasz
,
Alexandra Balbir Gurman
,
Pierluigi Meroni
,
Dominique Farge
,
Yair Levi
et al.
Article dans une revue
hal-04526702v1
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Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension
Ly Tu
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Agnes Desroches-Castan
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Christine Mallet
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Laurent Guyon
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Amélie Cumont
et al.
Article dans une revue
inserm-02581297v1
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Pulmonary arterial hypertension associated with protein kinase inhibitors: a pharmacovigilance–pharmacodynamic study
Lucie Cornet
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Charles Khouri
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Matthieu Roustit
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Christophe Guignabert
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Marie-Camille Chaumais
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Article dans une revue
hal-04172587v1
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Pathology and pathobiology of pulmonary hypertension: state of the art and research perspectives
Marc Humbert
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Christophe Guignabert
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Sébastien Bonnet
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Peter Dorfmüller
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James Klinger
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Article dans une revue
inserm-02612658v1
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Role of MIF and D-DT in immune-inflammatory, autoimmune, and chronic respiratory diseases: from pathogenic factors to therapeutic targets
Sven Günther
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Paolo Fagone
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Gaël Jalce
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Atanas Atanasov
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Christophe Guignabert
et al.
Article dans une revue
istex
hal-04526640v1
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Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
Nina Rol
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Michiel de Raaf
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Xiaoqing Sun
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Vincent Kuiper
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Denielli da Silva Gonçalves Bos
et al.
Article dans une revue
hal-04526643v1
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Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling
Kondababu Kurakula
,
Xiao-Qing Sun
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Chris Happé
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Denielli da Silva Goncalves Bos
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Robert Szulcek
et al.
Article dans une revue
inserm-02612640v1
|
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Hot topics in the mechanisms of pulmonary arterial hypertension disease: cancer-like pathobiology, the role of the adventitia, systemic involvement, and right ventricular failure
Edda Spiekerkoetter
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Elena Goncharova
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Christophe Guignabert
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Kurt Stenmark
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Grazyna Kwapiszewska
et al.
Article dans une revue
inserm-02612634v1
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Functional interaction between PDGFβ and GluN2B-containing NMDA receptors in smooth muscle cell proliferation and migration in pulmonary arterial hypertension
Marceau Quatredeniers
,
K Nakhleh Morad
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J Dumas Sebastien
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Audrey Courboulin
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C Vinhas Maria
et al.
Article dans une revue
hal-02411597v1
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Nouveau regard sur la physiopathologie de l’hypertension artérielle pulmonaire
Jennifer Bordenave
,
Ly Tu
,
Laurent Savale
,
Alice Huertas
,
Marc Humbert
et al.
Article dans une revue
inserm-02454990v1
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Response by Guignabert et al to Letter Regarding Article, “Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension”
Christophe Guignabert
,
Ly Tu
,
Jean-Jacques Feige
,
Marc Humbert
,
Sabine Bailly
Article dans une revue
hal-04526668v1
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Chronic Inflammation Within the Vascular Wall in Pulmonary Arterial Hypertension: More than a Spectator
Alice Huertas
,
Ly Tu
,
Marc Humbert
,
Christophe Guignabert
Article dans une revue
inserm-02454983v1
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Macrophage Migration Inhibitory Factor (MIF) Inhibition in a Murine Model of Bleomycin-Induced Pulmonary Fibrosis
Sven Günther
,
Jennifer Bordenave
,
Thông Hua-Huy
,
Carole Nicco
,
Amélie Cumont
et al.
Article dans une revue
inserm-02612651v1
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Precision medicine and personalising therapy in pulmonary hypertension: seeing the light from the dawn of a new era
Laurent Savale
,
Christophe Guignabert
,
Jason Weatherald
,
Marc Humbert
Article dans une revue
hal-04526519v1
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T-cell costimulation blockade is effective in experimental digestive and lung tissue fibrosis
Gonçalo Boleto
,
Christophe Guignabert
,
Sonia Pezet
,
Anne Cauvet
,
Jérémy Sadoine
et al.
Article dans une revue
hal-03828440v1
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Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension
Michael Bohnen
,
Lijiang Ma
,
Na Zhu
,
Hongjian Qi
,
Conor Mcclenaghan
et al.
Article dans une revue
hal-03985060v1
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ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad
Christophe Guignabert
,
Frances S de Man
,
Marc M. Lombès
Article dans une revue
inserm-02582393v1
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Therapeutic effect of pirfenidone in the sugen/hypoxia rat model of severe pulmonary hypertension
Paul-Benoit Poble
,
Carole Phan
,
Timothée Quatremare
,
Jennifer Bordenave
,
Raphaël Thuillet
et al.
Article dans une revue
inserm-02581079v1
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Design, Synthesis, and Biological Activity of New N -(Phenylmethyl)-benzoxazol-2-thiones as Macrophage Migration Inhibitory Factor (MIF) Antagonists: Efficacies in Experimental Pulmonary Hypertension
Morane Le Hiress
,
Bernardin Akagah
,
Guillaume Bernadat
,
Ly Tu
,
Raphaël Thuillet
et al.
Article dans une revue
inserm-02580381v1
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Pulmonary vascular endothelium: the orchestra conductor in respiratory diseases
Alice Huertas
,
Christophe Guignabert
,
Joan Barberà
,
Peter Bärtsch
,
Jahar Bhattacharya
et al.
Article dans une revue
hal-04526502v1
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|
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Editorial: Molecular Mechanisms in Pulmonary Hypertension and Right Ventricle Dysfunction
Harry Karmouty-Quintana
,
Christophe Guignabert
,
Grazyna Kwapiszewska
,
Mark Ormiston
Article dans une revue
hal-04526603v1
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|
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Ectopic upregulation of membrane-bound IL6R drives vascular remodeling in pulmonary arterial hypertension
Yuichi Tamura
,
Carole Phan
,
Ly Tu
,
Morane Le Hiress
,
Raphaël Thuillet
et al.
Article dans une revue
inserm-02580448v1
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|
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Switching-Off Adora2b in Vascular Smooth Muscle Cells Halts the Development of Pulmonary Hypertension
Tinne Mertens
,
Ankit Hanmandlu
,
Ly Tu
,
Carole Phan
,
Scott Collum
et al.
Article dans une revue
inserm-02580921v1
|
|
|
Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
Denielli da Silva Gonçalves Bós
,
Cathelijne van der Bruggen
,
Kondababu Kurakula
,
Xiao-Qing Sun
,
Karina Casali
et al.
Article dans une revue
hal-04526367v1
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|
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Pharmacovigilance in a rare disease: example of the VIGIAPATH program in pulmonary arterial hypertension
Marie-Camille Chaumais
,
Caroline O’connell
,
Laurent Savale
,
Christophe Guignabert
,
Frédéric Perros
et al.
Article dans une revue
hal-04526544v1
|
|
|
Loss-of-Function ABCC8 Mutations in Pulmonary Arterial Hypertension
Michael Bohnen
,
Lijiang Ma
,
Na Zhu
,
Hongjian Qi
,
Conor Mcclenaghan
et al.
Article dans une revue
hal-03983139v1
|
|
|
[IL6R is the key therapeutical target in pulmonary arterial hypertension]
Ly Tu
,
Carole Phan
,
Marc Humbert
,
Christophe Guignabert
Article dans une revue
inserm-02580983v1
|
|
|
Dasatinib increases endothelial permeability leading to pleural effusion
Carole Phan
,
Etienne-Marie Jutant
,
Ly Tu
,
Raphaël Thuillet
,
Andrei Seferian
et al.
Article dans une revue
inserm-02580192v1
|
|
|
Optimising experimental research in respiratory diseases: an ERS statement
Philippe Bonniaud
,
Aurélie Fabre
,
Nelly Frossard
,
Christophe Guignabert
,
Mark Inman
et al.
Article dans une revue
hal-01996906v1
|
|
|
Association Between BMI and Obesity With Survival in Pulmonary Arterial Hypertension
Jason Weatherald
,
Alice Huertas
,
Athénaïs Boucly
,
Christophe Guignabert
,
Yu Taniguchi
et al.
Article dans une revue
hal-04526565v1
|
|
|
Role of stromelysin 2 (matrix metalloproteinase 10) as a novel mediator of vascular remodeling underlying pulmonary hypertension associated with systemic sclerosis
Jérôme Avouac
,
Christophe Guignabert
,
Anna Maria Hoffmann-Vold
,
Barbara Ruiz
,
Peter Dorfmuller
et al.
Article dans une revue
hal-03828535v1
|
|
|
Vers de nouvelles cibles pour le traitement de l’hypertension artérielle pulmonaire : Importance des communications cellulaires
Ly Tu
,
Maria-Rosa Ghigna
,
Carole Phan
,
Jennifer Bordenave
,
Morane Le Hiress
et al.
Article dans une revue
inserm-02579962v1
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|
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Regulatory T Cell Dysfunction in Idiopathic, Heritable and Connective Tissue-Associated Pulmonary Arterial Hypertension
Alice Huertas
,
Carole Phan
,
Jennifer Bordenave
,
Ly Tu
,
Raphaël Thuillet
et al.
Article dans une revue
inserm-02593143v1
|
|
|
Dasatinib induces lung vascular toxicity and predisposes to pulmonary hypertension
Christophe Guignabert
,
Carole Phan
,
Andrei Seferian
,
Alice Huertas
,
Ly Tu
et al.
Article dans une revue
inserm-02579754v1
|
|
|
Telomere Maintenance Is a Critical Determinant in the Physiopathology of Pulmonary Hypertension
Mohamed Izikki
,
Eric Hoang
,
Irena Draskovic
,
Olaf Mercier
,
Florence Lecerf
et al.
Article dans une revue
hal-01764142v1
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|
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Leptin signalling system as a target for pulmonary arterial hypertension therapy
Alice Huertas
,
Ly Tu
,
Raphaël Thuillet
,
Morane Le Hiress
,
Carole Phan
et al.
Article dans une revue
inserm-02579431v1
|
|
|
Proinflammatory Signature of the Dysfunctional Endothelium in Pulmonary Hypertension. Role of the Macrophage Migration Inhibitory Factor/CD74 Complex
Morane Le Hiress
,
Ly Tu
,
Nicolas Ricard
,
Carole Phan
,
Raphaël Thuillet
et al.
Article dans une revue
inserm-02579320v1
|
|
|
Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension
Véronique Freund-Michel
,
Marcelina Cardoso dos Santos
,
Christophe Guignabert
,
David Montani
,
Carole Phan
et al.
Article dans une revue
hal-03329041v1
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|
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Role of Nerve Growth Factor in Development and Persistence of Experimental Pulmonary Hypertension
Véronique Freund-Michel
,
Marcelina Cardoso dos Santos
,
Christophe Guignabert
,
David Montani
,
Carole Phan
et al.
Article dans une revue
inserm-02578672v1
|
|
|
Clinical Pharmacology of Endothelin Receptor Antagonists Used in the Treatment of Pulmonary Arterial Hypertension
Marie-Camille Chaumais
,
Christophe Guignabert
,
Laurent Savale
,
Xavier Jaïs
,
Athénaïs Boucly
et al.
Article dans une revue
inserm-03224640v1
|
|
|
Increased Pericyte Coverage Mediated by Endothelial-Derived Fibroblast Growth Factor-2 and Interleukin-6 Is a Source of Smooth Muscle–Like Cells in Pulmonary Hypertension
Nicolas Ricard
,
Ly Tu
,
Morane Le Hiress
,
Alice Huertas
,
Carole Phan
et al.
Article dans une revue
inserm-02578269v1
|
|
|
Genome-wide association analysis identifies a susceptibility locus for pulmonary arterial hypertension
Marine Germain
,
Mélanie Eyries
,
David Montani
,
Odette Poirier
,
Barbara Girerd
et al.
Article dans une revue
hal-02565627v1
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|
|
Pulmonary arterial hypertension in patients treated by dasatinib.
David Montani
,
Emmanuel Bergot
,
Sven Günther
,
Laurent Savale
,
Anne Bergeron
et al.
Article dans une revue
inserm-00697146v1
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|
|
Leptin and regulatory T-lymphocytes in idiopathic pulmonary arterial hypertension.
Alice Huertas
,
Ly Tu
,
Natalia Gambaryan
,
Barbara Girerd
,
Frédéric Perros
et al.
Article dans une revue
inserm-00913076v1
|
|
|
A critical role for p130Cas in the progression of pulmonary hypertension in humans and rodents.
Ly Tu
,
Frances S. de Man
,
Barbara Girerd
,
Alice Huertas
,
Marie-Camille Chaumais
et al.
Article dans une revue
inserm-00905191v1
|
|
|
Dysregulated renin-angiotensin-aldosterone system contributes to pulmonary arterial hypertension.
Frances S. de Man
,
Ly Tu
,
Louis Handoko
,
Silvia Rain
,
Gerrina Ruiter
et al.
Article dans une revue
inserm-00905193v1
|
|
|
Autocrine fibroblast growth factor-2 signaling contributes to altered endothelial phenotype in pulmonary hypertension.
Ly Tu
,
Laurence Dewachter
,
Benoit Gore
,
Elie Fadel
,
Philippe Dartevelle
et al.
Article dans une revue
inserm-00579959v1
|
|
|
Bone morphogenetic protein signalling in heritable versus idiopathic pulmonary hypertension.
Laurence Dewachter
,
Serge Adnot
,
Christophe Guignabert
,
Ly Tu
,
Elisabeth Marcos
et al.
Article dans une revue
inserm-00433927v1
|
|
|
Dichloroacetate treatment partially regresses established pulmonary hypertension in mice with SM22alpha-targeted overexpression of the serotonin transporter.
Christophe Guignabert
,
Ly Tu
,
Mohamed Izikki
,
Laurence Dewachter
,
Patricia Zadigue
et al.
Article dans une revue
inserm-00499630v1
|
|
|
Tie2-mediated loss of peroxisome proliferator-activated receptor-gamma in mice causes PDGF receptor-beta-dependent pulmonary arterial muscularization.
Christophe Guignabert
,
Cristina Alvira
,
Tero-Pekka Alastalo
,
Hirofumi Sawada
,
Georg Hansmann
et al.
Article dans une revue
inserm-00499633v1
|
|
|
Endothelial-derived FGF2 contributes to the progression of pulmonary hypertension in humans and rodents.
Mohamed Izikki
,
Christophe Guignabert
,
Elie Fadel
,
Marc Humbert
,
Ly Tu
et al.
Article dans une revue
inserm-00499635v1
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|
|
Dual role for plasminogen activator inhibitor type 1 as soluble and as matricellular regulator of epithelial alveolar cell wound healing.
François Maquerlot
,
Stéphane D. Galiacy
,
Michel Malo
,
Christophe Guignabert
,
Daniel A. Lawrence
et al.
American Journal of Pathology, 2006, 169 (5), pp.1624-32
Article dans une revue
inserm-00186832v1
|
|
|
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension.
Christophe Guignabert
,
Mohamed Izikki
,
Ly Ieng Tu
,
Zhenlin Li
,
Patricia Zadigue
et al.
Article dans une revue
inserm-00499636v1
|
|
|
Effect of doxycycline on sulfur mustard-induced respiratory lesions in guinea pigs.
Christophe Guignabert
,
Laurent Taysse
,
Jean-Henri Calvet
,
Emmanuelle Planus
,
Séraphin Delamanche
et al.
Article dans une revue
inserm-00499644v1
|
|
|
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats.
Christophe Guignabert
,
Bernadette Raffestin
,
Rima Benferhat
,
William Raoul
,
Patricia Zadigue
et al.
Article dans une revue
inserm-00499643v1
|