Claire BERTRAND

Associate Professor
80 %
Libre accès
15
Documents
Affiliation actuelle
  • Dynamique des Génomes et Adaptation Microbienne (DynAMic)
Contact

Présentation

I am an Associate Professor at the University of Lorraine, where I have been working at the DynAMic laboratory since 2010. After postdoctoral training at the University of Lorraine and at Durham University (UK), I developed expertise in bacterial genetics and molecular biology. My research focuses on the molecular mechanisms underlying genetic plasticity in Streptomyces, soil bacteria with a remarkable capacity for environmental adaptation. In particular, I investigate DNA double-strand break repair pathways (NHEJ and homologous recombination), the role of the endonuclease NucS in gene fluxes, and the relationship between chromatin organization and chromosome compartmentalization. I teach genetics, molecular microbiology, and biotechnology, and I am actively involved in academic and educational responsibilities within the BioMIM curriculum and the Master’s program in Microbiology.

Domaines de recherche

Sciences du Vivant [q-bio]

Compétences

Molecular microbiology, genetics, bacteriology, genomics Recombination Horizontal Gene Transfer DNA Repair

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Publications

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Correction of non-random mutational biases along a linear bacterial chromosome by the mismatch repair endonuclease NucS

Oyut Dagva , Annabelle Thibessard , Jean-Noël Lorenzi , Victor Labat , Emilie Piotrowski et al.

Nucleic Acids Research, 2024, 52 (9), pp.5033-5047. ⟨10.1093/nar/gkae132⟩

Article dans une revue hal-04495979v1
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Bacterial NHEJ: A never ending story

Claire Bertrand , Annabelle Thibessard , Claude Bruand , François Lecointe , Pierre Leblond

Molecular Microbiology, 2019, 11, pp.1139-1151. ⟨10.1111/mmi.14218⟩

Article dans une revue hal-02044826v1
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Draft Whole-Genome Shotgun Sequence of Streptomyces sp. Strain ETH9427

Annabelle Thibessard , Cláudia M Vicente , Claire Bertrand , Bertrand Aigle , Pierre Leblond

Microbiology Resource Announcements, 2018, 7 (12), pp.e01197. ⟨10.1128/MRA.01197-18⟩

Article dans une revue hal-01887322v1
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Genome plasticity is governed by double strand break DNA repair in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond

Scientific Reports, 2018, 8 (1), pp.5272. ⟨10.1038/s41598-018-23622-w⟩

Article dans une revue hal-01757262v1
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Implication of RuvABC and RecG in homologous recombination in Streptomyces ambofaciens

Gregory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond

Research in Microbiology, 2017, 168 (1), pp.26-35. ⟨10.1016/j.resmic.2016.07.003⟩

Article dans une revue hal-01552147v1
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Multiple and Variable NHEJ-Like Genes Are Involved in Resistance to DNA Damage in Streptomyces ambofaciens

Grégory Hoff , Claire Bertrand , Lingli Zhang , Emilie Piotrowski , Ludovic Chipot et al.

Frontiers in Microbiology, 2016, 7, pp.1901. ⟨10.3389/fmicb.2016.01901⟩

Article dans une revue hal-01521993v1

Construction of pDYN6902, a new Streptomyces integrative expression vector designed for cloning sequences interfering with Escherichia coli viability

Annabelle Thibessard , Claire Bertrand , Julien Hiblot , Emilie Piotrowski , Pierre Leblond

Plasmid, 2015, 82, pp.43-49. ⟨10.1016/j.plasmid.2015.10.003⟩

Article dans une revue hal-01258339v1
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The adnAB Locus, Encoding a Putative Helicase-Nuclease Activity, Is Essential in Streptomyces

L. Zhang , Cong Tu Nguyen , L. Chipot , E. Piotrowski , C. Bertrand et al.

Journal of Bacteriology, 2014, 196 (14), pp.2701 - 2708. ⟨10.1128/JB.01513-14⟩

Article dans une revue hal-01474715v1
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Arabidopsis HAF2 gene encoding TATA-binding protein (TBP)-associated factor TAF1, is required to integrate light signals to regulate gene expression and growth

Claire Bertrand , Moussa Benhamed , You-Fang Li , Mira Ayadi , Gaetan G. Lemonnier et al.

Journal of Biological Chemistry, 2005, 280 (2), pp.1465-1473. ⟨10.1074/jbc.M409000200⟩

Article dans une revue hal-02675476v1
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Arabidopsis Histone Acetyltransferase AtGCN5 Regulates the Floral Meristem Activity through the WUSCHEL/AGAMOUS Pathway

Claire Bertrand , Catherine Bergounioux , Séverine Domenichini , Marianne Delarue , Dao-Xiu Zhou

Journal of Biological Chemistry, 2003, 278 (30), pp.28246 - 28251. ⟨10.1074/jbc.m302787200⟩

Article dans une revue hal-05242274v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond

Prokagenomics 2017 7th European Conference on Prokaryotic and Fungal Genomics, Sep 2017, Göttingen, Germany

Communication dans un congrès hal-01655261v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Stephen T Mcgovern , François Lecointe et al.

International Symposium on the Biology of Actinomycetes, May 2017, Jeju, South Korea

Communication dans un congrès hal-01655226v1

Double strand break repair triggers genome plasticity in Streptomyces

Grégory Hoff , Claire Bertrand , Emilie Piotrowski , Annabelle Thibessard , Pierre Leblond

Actino2017 Journées des Actinobactéries, Oct 2017, Lyon, France

Communication dans un congrès hal-01655543v1

Nonhomologous End-Joining in Bacteria

Annabelle Thibessard , Claire Bertrand , Edward J Bartlett , Aidan J Doherty , Claude Bruand et al.

Joseph Jez. Encyclopedia of Biological Chemistry 3rd Edition,, 4, Elsevier, 2021, 9780128194607

Chapitre d'ouvrage hal-03319644v1