Daniel Dory

Scientific researcher (Principal Investigator) in avian virology, immunology, and vaccinology,

Documents

Affiliation actuelle

Virologie, Immunologie, Parasitologie Avaires et Cunicoles (VIPAC)

Identifiants chercheurs

Contact

Présentation

As a scientific researcher (Principal Investigator) in avian virology, immunology, and vaccinology, I contribute to the development of new tools for characterizing the immune response (humoral and cellular), the development and/or evaluation of vaccines, and studies on IBDV (Infectious bursal disease virus), avian coronaviruses, and avian metapneumoviruses.

This work is part of the WHOA (World Organization for Animal Health) reference laboratory on Infectious Bursal Disease (Gumboro Disease) and Turkey rhinotracheitis.

From 2002 to 2024, I was a project manager and team leader in swine immunology and virology, still at ANSES in Ploufragan. I specifically studied the efficacy and biosafety of DNA vaccination in pigs, using Aujeszky's disease (herpesvirus) as a reference model. I also participated in a study on foot-and-mouth disease vaccination in pigs and Campylobacter vaccination in chickens. The vaccine candidates were selected using the reverse vaccination strategy. Finally, I initiated antibody repertoire analysis studies in pigs as well as antigen-antibody modeling studies. I also participated in an assessment for the European marketing of a DNA vaccine for veterinary use by the European Medicines Agency.

Domaines de recherche

Sciences du Vivant [q-bio]

Publications

	Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific humoral immune response after vaccination and challenge Valentin Herbet , Edouard Hirchaud , Yannick Blanchard , Véronique Beven , Léon-Charles Tranchevent et al. 2026 Pré-publication, Document de travail hal-05712452v1

	Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific immune response after vaccination and challenge Valentin Herbet , Edouard Hirchaud , Yannick Blanchard , Véronique Beven , Léon-Charles Tranchevent et al. Discovery Immunology, 2026, 5 (1), ⟨10.1093/discim/kyag009⟩ Article dans une revue anses-05662779v1
	Reverse vaccinology: A strategy also used for identifying potential vaccine antigens in poultry Noémie Gloanec , Muriel Guyard-Nicodème , Marianne Chemaly , Daniel Dory Vaccine, 2025, 48, pp.126756. ⟨10.1016/j.vaccine.2025.126756⟩ Article dans une revue anses-04933934v1
	Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection Ludivine Percevault , Léon-Charles Tranchevent , Lionel Bigault , Maxime Berthaud , Damien Le Gloahec et al. Veterinary Research, 2025, 56 (1), pp.221. ⟨10.1186/s13567-025-01657-y⟩ Article dans une revue hal-05385997v1
	Evaluation of Two Recombinant Protein-Based Vaccine Regimens against Campylobacter jejuni: Impact on Protection, Humoral Immune Responses and Gut Microbiota in Broilers Noémie Gloanec , Muriel Guyard-Nicodème , Raphaël Brunetti , Ségolène Quesne , Alassane Keita et al. Animals, 2023, 13 (24), pp.3779. ⟨10.3390/ani13243779⟩ Article dans une revue anses-04350409v1
	Plasmid DNA Prime/Protein Boost Vaccination against Campylobacter jejuni in Broilers: Impact of Vaccine Candidates on Immune Responses and Gut Microbiota Noémie Gloanec , Muriel Guyard-Nicodème , Raphaël Brunetti , Ségolène Quesne , Alassane Keita et al. Pharmaceutics, 2023, 15 (5), pp.1397. ⟨10.3390/pharmaceutics15051397⟩ Article dans une revue anses-04123731v1
	Research Note: Analysis of immune responses in broilers after vaccination against Campylobacter jejuni Noémie Gloanec , Daniel Dory , Ségolène Quesne , Véronique Béven , Typhaine Poezevara et al. Poultry Science, 2023, 102 (4), pp.102510. ⟨10.1016/j.psj.2023.102510⟩ Article dans une revue anses-04040798v1
	Terrorisme au Pérou : le Sentier Lumineux revisité par la géographie Daniel Dory , Hervé Théry Sécurité globale, 2022, N° 32 (4), pp.75-85. ⟨10.3917/secug.224.0075⟩ Article dans une revue halshs-03932011v1
	Intranasal inoculations of naked or PLGA-PEI nanovectored DNA vaccine induce systemic and mucosal antibodies in pigs: A feasibility study Laurent Souci , Hervé Jaunet , Gérald Le Diguerher , Jean-Marie Guionnet , Véronique Béven et al. Research in Veterinary Science, 2020, 132, pp.194-201. ⟨10.1016/j.rvsc.2020.06.018⟩ Article dans une revue hal-03093878v1
	Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation Daniel Dory , Vincent Le Moigne , Roland Cariolet , Véronique Béven , André Keranflec et al. Journal of Immunology Research, 2015 Article dans une revue hal-03715864v1
	The protective immune response against Pseudorabies virus induced by DNA vaccination is impaired if the plasmid harbors a functional Porcine circovirus type 2 rep and origin of replication. Florence Faurez , Béatrice Grasland , Véronique Béven , Roland Cariolet , André Keranflec'H et al. Antiviral Research, 2012, 96 (3), pp.271-9. ⟨10.1016/j.antiviral.2012.09.024⟩ Article dans une revue istex inserm-00872623v1

	Kinetic profiling of pig antibody repertoires: CDRH3-based identification of pseudorabies-specific antibodies Valentin Herbet , Véronique Béven , Edouard Hirchaud , Lionel Bigault , Aurelie Le Roux et al. 5ème workshop Centres Germinatifs, Jun 2025, Saint-Malo, France Poster de conférence hal-05712514v1
	Contribution of intestinal porcine organoids to the study of host-virus interactions of transmissible gastroenteritis virus Ludivine Percevault , Lionel Bigault , Maxime Berthaud , Aurélie Leroux , Pierrick Lucas et al. Epizone, 16th annual meeting 2024, Sep 2024, Uppsala, Sweden. , pp.68, 2024 Poster de conférence anses-04834582v1
	Apport des organoïdes porcins dans l’étude des interactions moléculaires hôtes-pathogènes du virus de la gastro-entérite transmissible Ludivine Percevault , Lionel Bigault , Maxime Berthaud , Aurélie Le Roux , Pierrick Lucas et al. XXVIes Journées francophones de virologie, Apr 2024, Liège, Belgique. 2024 Poster de conférence anses-04694301v1
	Porcine Intestinal Organoids for the Study of Host-Pathogen Porcine Enteric Viruses Maud Contrant , Lionel Bigault , Ludivine Percevault , Camille Duchesne , Frédéric Paboeuf et al. 12th International congress for veterinary virology (ESVV), Sep 2023, Ghent, Belgium. pp.96 Poster de conférence hal-05712589v1
	Utilisation des organoïdes intestinaux porcins pour l’étude des relations hôtes-pathogènes dans le cadre du projet PigOrg : le modèle des coronavirus entériques porcins Maud Contrant , Lionel Bigault , Ludivine Percevault , Camille Duchesne , Frédéric Paboeuf et al. Séminaire "Organoïdes et recherche agronomique", Jun 2022, Maisons-Alfort, France Poster de conférence hal-05712595v1

	Evaluation des réponses immunitaires suite à la vaccination contre Campylobacter chez deux souches aviaires diffèrentes Noémie Gloanec , Muriel Guyard-Nicodème , Ségolène Quesne , Véronique Béven , Typhaine Poezevara et al. 14èmes Journées de la Recherche Avicole et des Palmipèdes à Foie Gras, Mar 2022, Tours, France Communication dans un congrès anses-04082360v1
	Immune responses and caecal microbiota composition in response to Campylobacter vaccination in poultry: 3 years of thesis in 3 minutes Noemie Gloanec , Muriel Guyard-Nicodème , Raphael Brunetti , Ségolène Quesne , Véronique Béven et al. Journées Scientifiques et Doctorales de l'ANSES (JSDA) 2022, Oct 2022, Maisons-Alfort, France Communication dans un congrès anses-03855729v1

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Daniel Dory

Présentation

Domaines de recherche

Publications

Publications

Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific humoral immune response after vaccination and challenge

Profiling of porcine B-cell receptor heavy-chain repertoires indicates the development of a wide public pseudorabies virus-specific immune response after vaccination and challenge

Reverse vaccinology: A strategy also used for identifying potential vaccine antigens in poultry

Relevance of porcine intestinal organoids as a surrogate for animal experimentation: application to the investigation of host–virus interactions during porcine coronavirus infection

Evaluation of Two Recombinant Protein-Based Vaccine Regimens against Campylobacter jejuni: Impact on Protection, Humoral Immune Responses and Gut Microbiota in Broilers

Plasmid DNA Prime/Protein Boost Vaccination against Campylobacter jejuni in Broilers: Impact of Vaccine Candidates on Immune Responses and Gut Microbiota

Research Note: Analysis of immune responses in broilers after vaccination against Campylobacter jejuni

Terrorisme au Pérou : le Sentier Lumineux revisité par la géographie

Intranasal inoculations of naked or PLGA-PEI nanovectored DNA vaccine induce systemic and mucosal antibodies in pigs: A feasibility study

Targeted Collection of Plasmid DNA in Large and Growing Animal Muscles 6 Weeks after DNA Vaccination with and without Electroporation

The protective immune response against Pseudorabies virus induced by DNA vaccination is impaired if the plasmid harbors a functional Porcine circovirus type 2 rep and origin of replication.

Kinetic profiling of pig antibody repertoires: CDRH3-based identification of pseudorabies-specific antibodies

Contribution of intestinal porcine organoids to the study of host-virus interactions of transmissible gastroenteritis virus

Apport des organoïdes porcins dans l’étude des interactions moléculaires hôtes-pathogènes du virus de la gastro-entérite transmissible

Porcine Intestinal Organoids for the Study of Host-Pathogen Porcine Enteric Viruses

Utilisation des organoïdes intestinaux porcins pour l’étude des relations hôtes-pathogènes dans le cadre du projet PigOrg : le modèle des coronavirus entériques porcins

Evaluation des réponses immunitaires suite à la vaccination contre Campylobacter chez deux souches aviaires diffèrentes

Immune responses and caecal microbiota composition in response to Campylobacter vaccination in poultry: 3 years of thesis in 3 minutes