Delphine SAPALY

9
Documents
Affiliation actuelle
  • Health and Functional Exposomics (HealthFex | U1124)
Identifiants chercheurs

Publications

Publications

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Drug Candidate BIO101 for Spinal Muscular Atrophy as Monotherapy or Combined With the Antisense Oligonucleotide ASO‐10‐27

Cynthia Bézier , Steve Cottin , Parvin Nazari Hashemi , Mirella El Khoury , Zoé Clerc et al.
Journal of Cachexia, Sarcopenia and Muscle, 2025, 16 (5), pp.e70104. ⟨10.1002/jcsm.70104⟩
Article dans une revue hal-05453886 v1

Combining SMN2 splicing modifiers with HDAC6 inhibition greatly improves muscle function and survival in Spinal Muscular Atrophy

Alexis Osseni , Rasha Slika , Laurent Coudert , Agnes Conjard-Duplany , Laure Weill et al.
Article dans une revue hal-05044738 v1

The analysis of the skeletal muscle metabolism is crucial for designing optimal exercise paradigms in type 2 diabetes mellitus

Elias Abi Akar , Laure Weill , Mirella El Khoury , Cédric Caradeuc , Gildas Bertho et al.
Molecular Medicine, 2024, 30 (1), pp.80. ⟨10.1186/s10020-024-00850-7⟩
Article dans une revue hal-05316643 v1
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Dysregulation of muscle cholesterol transport in amyotrophic lateral sclerosis

D. Sapaly , F. Cheguillaume , L. Weill , Z. Clerc , O. Biondi et al.
Brain - A Journal of Neurology , 2024, Brain, 148 (3), p.788-802. ⟨10.1093/brain/awae270⟩
Article dans une revue hal-04977711 v1

NADPH oxidase 4 inhibition is a complementary therapeutic strategy for spinal muscular atrophy

Mirella El Khoury , Olivier Biondi , Gaelle Bruneteau , Delphine Sapaly , Sabrina Bendris et al.
Frontiers in Cellular Neuroscience, 2023, 17, ⟨10.3389/fncel.2023.1242828⟩
Article dans une revue hal-04495927 v1
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Activating ATF6 in spinal muscular atrophy promotes SMN expression and motor neuron survival through the IRE1α‐XBP1 pathway

Domenico d'Amico , Olivier Biondi , Camille Januel , Cynthia Bezier , Delphine Sapaly et al.
Neuropathology and Applied Neurobiology, 2022, 48 (5), pp.e12816. ⟨10.1111/nan.12816⟩
Article dans une revue inserm-04385529 v1
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The Small-Molecule Flunarizine in Spinal Muscular Atrophy Patient Fibroblasts Impacts on the Gemin Components of the SMN Complex and TDP43, an RNA-Binding Protein Relevant to Motor Neuron Diseases

Delphine Sapaly , Perrine Delers , Jennifer Coridon , Badih Salman , Franck Letourneur et al.
Frontiers in Molecular Biosciences, 2020, 7, pp.55. ⟨10.3389/fmolb.2020.00055⟩
Article dans une revue hal-05453823 v1
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Low-Intensity Running and High-Intensity Swimming Exercises Differentially Improve Energy Metabolism in Mice With Mild Spinal Muscular Atrophy

Léo Houdebine , Domenico d'Amico , Jean Bastin , Farah Chali , Céline Desseille et al.
Frontiers in Physiology, 2019, 10, pp.1258. ⟨10.3389/fphys.2019.01258⟩
Article dans une revue inserm-02893893 v1
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Small-molecule flunarizine increases SMN protein in nuclear Cajal bodies and motor function in a mouse model of spinal muscular atrophy

Delphine Sapaly , Matthieu Dos Santos , Perrine Delers , Olivier Biondi , Gwendoline Quérol et al.
Scientific Reports, 2018, 8 (1), pp.2075. ⟨10.1038/s41598-018-20219-1⟩
Article dans une revue pasteur-02090360 v1