Eloise Thomas

Eloïse Thomas - Maîtresse de Conférences Université Claude Bernard Lyon 1, France LAGEPP : Laboratoire d'Automatique, de Génie des Procédés et de Génie Pharmaceutique - UMR5007 CNRS - France. ISPB : Institut des Sciences Pharmaceutiques et Biologiques - Faculté de Pharmacie de Lyon - France.
59
Documents
Affiliation actuelle
  • Laboratoire d'automatique, de génie des procédés et de génie pharmaceutique (LAGEPP)
Contact

Présentation

Thématique de recherche : Génie Pharmaceutique, formulation de produits de santé

  • Systèmes de délivrance contrôlée et/ou ciblée d’actifs thérapeutiques (nanoparticules, hydrogels, microparticules)
  • Formulation d’agents de contraste pour l’imagerie médicale et plateformes théranostiques
  • Décontamination contre les toxiques
  • Synthèse, caractérisations physico-chimiques, évaluation in vitro et in vivo sur petit animal

Domaines de recherche

Sciences pharmaceutiques

Publications

19
13
12
12
12
11
9
9
7
7
7
6
6
6
6
5
5
5
4
4
4
4
4
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
33
9
6
4
2
1
1
1
1
1
26
23
7
3

Publications

Image document

Focus on therapeutic peptides and their delivery

Elise Rosson , François Lux , L. David , Yann Godfrin , Olivier Tillement et al.
International Journal of Pharmaceutics, 2025, 675, pp.125555. ⟨10.1016/j.ijpharm.2025.125555⟩
Article dans une revue (article de synthèse) hal-05078046 v1
Image document

Functionalization of chitosan with a polycarboxylic macrocycle yields injectable hydrogel with pH and salts responsiveness

Arthur Durand , Thomas Gréa , Gabin Lebeau , Guillaume Jacquot , Augustin Tillement et al.
Materials Today Advances, 2025, 25, pp.100565. ⟨10.1016/j.mtadv.2025.100565⟩
Article dans une revue hal-04967331 v1
Image document

Tailor-Made Synthesis of Cerium Oxide Nanoparticles for Improving the Skin Decontamination of Paraoxon

Eloise Thomas , Stephanie Briancon , Frédéric Chaput , Greta Camilla Magnano , Isabelle Trenque et al.
ACS APPLIED NANO MATERIALS, 2024, 7, pp.16052-16065. ⟨10.1021/acsanm.4c01830⟩
Article dans une revue hal-04672854 v1

Anti-Netrin-1 decorated nanoparticles combined with chemotherapy for the treatment of triple-negative breast cancer

Silvia Breusa , Eloise Thomas , Noemi Baldinotti , Serena Zilio , Jean-Guy Delcros et al.
Biomaterials Advances, 2024, 161, pp.213881. ⟨10.1016/j.bioadv.2024.213881⟩
Article dans une revue hal-04577330 v1
Image document

CeO2-based peelable gel for neutralization and skin decontamination toward chemical warfare agents

Eloise Thomas , Claire Bordes , Fréderic Chaput , Delphine Arquier , Stéphanie Briançon et al.
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 687, pp.133520. ⟨10.1016/j.colsurfa.2024.133520⟩
Article dans une revue hal-04480655 v1
Image document

Combating lead and cadmium exposure with an orally administered chitosan-based chelating polymer

Jordyn Ann Howard , Halyna Kuznietsova , Natalia Dziubenko , Axel Aigle , Marco Natuzzi et al.
Scientific Reports, 2023, 13 (1), pp.2215. ⟨10.1038/s41598-023-28968-4⟩
Article dans une revue hal-04209149 v1
Image document

Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies

Thomas Gréa , Guillaume Jacquot , Arthur Durand , Clélia Mathieu , Adeline Gasser et al.
Advanced Materials, 2023, 36 (13), pp.2308738. ⟨10.1002/adma.202308738⟩
Article dans une revue hal-04728163 v1
Image document

Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma

Eloise Thomas , Clélia Mathieu , Patricia Moreno‐gaona , Vincent Mittelheisser , François Lux et al.
Advanced Healthcare Materials, 2021, pp.2101565. ⟨10.1002/adhm.202101565⟩
Article dans une revue hal-03469640 v1

3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation

Irini Skaripa-Koukelli , David Hauton , John Walsby-Tickle , Eloise Thomas , Joshua Owen et al.
Cancer & Metabolism, 2021, 9 (1), ⟨10.1186/s40170-021-00273-6⟩
Article dans une revue hal-03379071 v1
Image document

Feasibility study and direct extraction of endogenous free metallic cations combining hemodialysis and chelating polymer

Marco Natuzzi , Coralie Grange , Thomas Gréa , Thomas Brichart , Axel Aigle et al.
Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-99462-y⟩
Article dans une revue hal-03379081 v1

Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation

Joshua Owen , Eloise Thomas , Jyothi Menon , Michael Gray , Irini Skaripa-Koukelli et al.
Journal of Controlled Release, 2020, 319, pp.222-233. ⟨10.1016/j.jconrel.2019.12.045⟩
Article dans une revue hal-02547889 v1
Image document

Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers

S. Huclier-Markai , E. Ntsiba , Eloise Thomas , C. Alliot , Cs Cutler et al.
Int.J.Med.Nano Res., 2019, 6 (1), pp.027. ⟨10.23937/2378-3664.1410027⟩
Article dans une revue hal-02317372 v1
Image document

Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging

Vivek Thakare , Vu-Long Tran , Marco Natuzzi , Eloise Thomas , Mathieu Moreau et al.
RSC Advances, 2019, 9 (43), pp.24811-24815. ⟨10.1039/C9RA00365G⟩
Article dans une revue hal-02287597 v1
Image document

AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

François Lux , Vu Long Tran , Eloise Thomas , Sandrine Dufort , Fabien Rossetti et al.
British Journal of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩
Article dans une revue (article de synthèse) hal-01935540 v1

Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Irini Skaripa-Koukelli , Sheena Wallington et al.
Theranostics, 2019, 9 (19), pp.5595-5609. ⟨10.7150/thno.34669⟩
Article dans une revue hal-02287691 v1
Image document

Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance–Computed Tomography Image Guided Radiation Therapy

Alexandre Detappe , Eloise Thomas , Mark W Tibbitt || , Sijumon Kunjachan , Oksana Zavidij et al.
Nano Letters, 2017, 17 (3), pp.1733 - 1740. ⟨10.1021/acs.nanolett.6b05055⟩
Article dans une revue hal-01689566 v1
Image document

Proton MR spectroscopy and diffusion MR imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma

Magali Toussaint , Sophie Pinel , Florent Auger , Nicolas Durieux , Magalie Thomassin et al.
Theranostics, 2017, 7 (2), pp.436-451. ⟨10.7150/thno.17218⟩
Article dans une revue hal-01399256 v1
Image document

68 Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy

Penelope Bouziotis , Dimitris Stellas , Eloise Thomas , Charles Truillet , Charalampos Tsoukalas et al.
Nanomedicine, 2017, 12 (13), pp.1561 - 1574. ⟨10.2217/nnm-2017-0032⟩
Article dans une revue hal-01689547 v1
Image document

Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma

Eloise Thomas , Ludovic Colombeau , Mickaël Gries , Thibaut Peterlini , Clélia Mathieu et al.
International Journal of Nanomedicine, 2017, 12, pp.7075-7088. ⟨10.2147/IJN.S141559⟩
Article dans une revue hal-01643075 v1

Synthesis and Characterization of 89 Zr-Labeled Ultrasmall Nanoparticles

Charles Truillet , Eloise Thomas , François Lux , Loc T Huynh , Olivier Tillement et al.
Molecular Pharmaceutics, 2016, 13 (7), pp.2596 - 2601. ⟨10.1021/acs.molpharmaceut.6b00264⟩
Article dans une revue hal-01405878 v1
Image document

Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection

Lucie Sancey , Shady Kotb , Charles Truillet , F. Appaix , Arthur Marais et al.
ACS Nano, 2015, 9 (3), pp.2477-2488. ⟨10.1021/acsnano.5b00552⟩
Article dans une revue hal-01207383 v1

Zwitterionic Biodegradable Hydrogels for Sustained Therapeutic Peptide Delivery

Elise Rosson , Eloise Thomas , Alexandra Weber , Jacqueline Taleb Sidi-Boumedine , David Kryza et al.
Nanohybrid XXI, May 2025, Porquerolles, France
Communication dans un congrès hal-05078087 v1

Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies

Elise Rosson , François Lux , Alexandra Weber , Jacqueline Sidi Boumedine , David Kryza et al.
Advanced Drug and Gene Delivery Systems symposium, Jan 2025, Lyon, France
Communication dans un congrès hal-04924331 v1

Biodegradable hydrogel for sustained release of therapeutic peptide

Elise Rosson , Eloise Thomas , François Lux , Alexandra Weber , Jacqueline Sidi-Boumedine et al.
Nanohybrid XX, May 2024, Bastia, France
Communication dans un congrès hal-04694239 v1

Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies

Elise Rosson , François Lux , Alexandra Weber , Jacqueline Sidi Boumedine , David Kryza et al.
BNLF 2024 CRS meeting, BNLF local chapter CRS, Oct 2024, Ghent, Belgium
Communication dans un congrès hal-04765505 v1

Peptide formulation and development of a novel delivery system for the treatment of neurological pathologie

Elise Rosson , Eloise Thomas , François Lux , Alexandra Weber , Thomas Brichart et al.
Nanohybrides XIX, May 2023, Porquerolles, France
Communication dans un congrès hal-04691977 v1

Towards the Synthesis and Delivery of Halogenated MCT1 Substrates

Irini Skaripa-Koukelli , John Walsby-Tickle , Joshua Owen , Eloise Thomas , James Mccullagh et al.
Oncological Drug Delivery Conference, Sep 2019, Oxford, United Kingdom
Communication dans un congrès hal-03989472 v1

Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy

Katherine A. Vallis , Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington et al.
Annual Congress of the European Association of Nuclear Medicine, Oct 2019, Barcelona, Spain. pp.1-952, ⟨10.1007/s00259-019-04486-2⟩
Communication dans un congrès hal-02548480 v1

Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma

Noémie Thomas , Mickaël Gries , Ludovic Colombeau , Eloise Thomas , Cédric Boura et al.
International Conference on Porphyrins and Phthalocyanines, ICCP-10, Jul 2018, Munich, Germany
Communication dans un congrès hal-01845326 v1

AGuIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors

Ludovic Colombeau , Eloise Thomas , Noémie Thomas , Muriel Barberi-Heyob , François Lux et al.
17th Congress of the European Society for Photobiology, Sep 2017, Pise, Italy
Communication dans un congrès hal-02550754 v1

Functionalization of AGuIX nanoparticles for improved radiotherapy

Eloise Thomas , Alexandre Detappe , Ross Berbeco , François Lux , Olivier Tillement
Nano-Hybrides n°14, May 2017, Bastia, France
Communication dans un congrès hal-02548188 v1

Vascular targeting for the treatment of glioblastoma by PDT

Céline Frochot , Ludovic Colombeau , Eloise Thomas , Régis Vanderesse , Magali Toussaint et al.
16th International Photodynamic Association World Congress, IPA 2017, Jun 2017, Coimbra, Portugal
Communication dans un congrès hal-03243053 v1

Gadolinium-based nanoparticles for the treatment of glioblastoma by MRI-guided photodynamic therapy

Eloise Thomas , Magali Toussaint , Ludovic Colombeau , Mickaël Gries , Thibaut Peterlini et al.
World Molecular Imaging Congress, WMIC 2017, Sep 2017, Philadelphia, United States
Communication dans un congrès hal-02548177 v1

Use of MR Imaging and proton MR Spectroscopy imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma

Magali Toussaint , Florent Auger , Sophie Pinel , Magalie Thomassin , Eloise Thomas et al.
Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France
Communication dans un congrès hal-01407476 v1

Interstitial photodynamic therapy for glioblastoma: interest of MRI monitoring to predict iPDT effects.

Magali Toussaint , Florent Auger , Sophie Pinel , Nicolas Durieux , Magalie Thomassin et al.
13e Colloque Nano-hybrides, ILM, Lyon 1, May 2016, Porquerolles, France
Communication dans un congrès hal-01312929 v1

Ultrasmall nanoparticles functionalization for PET and SPECT imaging

Eloise Thomas , François Lux , Olivier Tillement
Nano-Hybrides n°12, May 2015, Bastia, France
Communication dans un congrès hal-02548199 v1

Development of new synthesis protocol and advanced characterization of AGuIX Nanoparticle

Vu Long Tran , Arthur Marais , Eloise Thomas , Cédric Louis , François Lux et al.
ITN-ARGENT, Nov 2015, Obergurgl, Austria
Communication dans un congrès hal-03989480 v1

AGuIX nanoparticles for PET/MRI

François Lux , Lucie Sancey , Eloise Thomas , Olivier Tillement
France Life Imaging, Dec 2014, Lyon, France
Communication dans un congrès hal-02548210 v1

Development of Tungsten-based contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.
European Molecular Imaging Meeting, Mar 2025, Bilbao, Spain
Poster de conférence hal-05078095 v1

Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification

Solène Fukuhara , C. Charcosset , Eloise Thomas
BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium
Poster de conférence hal-04765479 v1

Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.
SF Nano, Dec 2024, Toulouse, France
Poster de conférence hal-04924322 v1

Biodegradable hydrogel for sustained release of therapeutic peptide

Elise Rosson , Eloise Thomas , Alexandra Weber , Jacqueline Sidi-Boumedine , David Kryza et al.
PBP world meeting (Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology), Mar 2024, Vienne (AUT), Austria
Poster de conférence hal-04694250 v1

Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification

Solène Fukuhara , C. Charcosset , Eloise Thomas
SF Nano, Dec 2024, Toulouse, France
Poster de conférence hal-04924327 v1

Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.
BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium
Poster de conférence hal-04765470 v1

CeO2-based peelable gel for neutralization and skin decontamination toward chemical warefare agent simulants

Eloise Thomas , Delphine Arquier , C. Barratier , Claire Bordes , Fréderic Chaput et al.
Formula XI, Jul 2023, Lille, France
Poster de conférence hal-04462743 v1

Monoclonal antibodies decorated nanoparticles for the treatment of triple negative breast cancer

Silvia Breusa , Jean‐guy Delcros , Eloise Thomas , Serena Zilio , Diana Marcela Hernandez Palomino et al.
SFNano Annual Meeting, Dec 2022, Strasbourg, France
Poster de conférence hal-03989500 v1

Ultrasound-Mediated Cavitation To Enhance The Delivery Of Liposomal Formulations For Targeted Radionuclide Therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington , Michael Gray et al.
Controlled Release Society Annual Meeting, Jul 2019, Valencia, Spain
Poster de conférence hal-02548225 v1

Ultrasound And Microbubbles Enhance The Delivery Of A Liposomal Formulation For Targeted Chemo-Radionuclide Therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington , Michael Gray et al.
British Nuclear Medicine Society Spring Meeting, Apr 2019, Oxford, United Kingdom
Poster de conférence hal-02548236 v1

Indium-111 afterloading of preformed EGF containing liposomes for molecularly targeted radionuclide delivery via ultrasound induced cavitation.

Joshua Owen , Jyothi Menon , Eloise Thomas , Irini Skaripa-Koukelli , Martin Gill et al.
Annual Congress of the European Association of Nuclear Medicine, Oct 2018, Düsseldorf, Germany. European Journal of Nuclear Medicine and Molecular Imaging, 45 (S1), pp.1-844, 2019, ⟨10.1007/s00259-018-4148-3⟩
Poster de conférence hal-02548464 v1

Targeted and combined chemo-radionucleide therapy for the treatment of breast cancers

Eloise Thomas , Jyothi Menon , Joshua Owen , Irini Skaripa-Koukelli , Robert Carlisle et al.
CRUK Symposium, Jun 2018, Oxford, United Kingdom
Poster de conférence hal-02548247 v1

Silica-Based Bismuth-Gadolinium Nanoparticles for MRI and CT Image-Guided Radiation Therapy

Alexandre Detappe , Eloise Thomas , M. Tibbitt , S. Kunjachan , O. Zavidij et al.
ASTRO annual meeting, Sep 2017, San Diego, United States
Poster de conférence hal-03989491 v1

Radiolabeling for long term biodistribution of ultrasmall nanoparticles designed for radiotherapy guided by MRI

Eloise Thomas , Charles Truillet , Franck Denat , François Lux , Frederic Boschetti et al.
World Molecular Imaging Congress, Sep 2016, New-York, United States
Poster de conférence hal-02548258 v1

PET and MR imaging with 64Cu/68Ga-labeled AGuIX ultra-small nanoparticles in tumor-bearing mice

Marie-Caline Abadjian , Eloise Thomas , Joseph Latoche , Lesley Foley , Kathryn Day et al.
SNMMI Annual Meeting, Jun 2016, San Diego, United States. 57 (Supplement2), pp.1181, 2016
Poster de conférence hal-02548345 v1

AGUIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors

Ludovic Colombeau , Eloise Thomas , Thibaut Peterlini , Mickaël Gries , Noémie Thomas et al.
Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , 17, pp.A71, 2017, ⟨10.1016/j.pdpdt.2017.01.161⟩
Poster de conférence hal-01408883 v1

Ultrasmall gadolinium-based nanoparticles designed for photodynamic therapy (PDT) guided by MRI

E Thomas , M Toussaint , Ludovic Colombeau , Céline Frochot , Régis Vanderesse et al.
Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , Photodiagnosis and Photodynamic Therapy, 17, pp.A60, 2017, ⟨10.1016/j.pdpdt.2017.01.136⟩
Poster de conférence hal-01498485 v1

Functionalization of ultrasmall nanoparticles for theranosctic applications

Eloise Thomas , Frederic Boschetti , Franck Denat , François Lux , Olivier Tillement
COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2015, Belgrade, Serbia
Poster de conférence hal-02548269 v1

AGuIX modifications for active tumor targeting and radiolabelling

Eloise Thomas , Charles Truillet , Marie Plissonneau , Frederic Boschetti , Franck Denat et al.
COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2014, Istanbul, Turkey
Poster de conférence hal-02548293 v1