Eloise Thomas

Eloïse Thomas - Maîtresse de Conférences Université Claude Bernard Lyon 1, France LAGEPP : Laboratoire d'Automatique, de Génie des Procédés et de Génie Pharmaceutique - UMR5007 CNRS - France. ISPB : Institut des Sciences Pharmaceutiques et Biologiques - Faculté de Pharmacie de Lyon - France.
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Documents
Affiliation actuelle
  • Laboratoire d'automatique, de génie des procédés et de génie pharmaceutique (LAGEPP)
Contact

Présentation

Thématique de recherche : Génie Pharmaceutique, formulation de produits de santé

  • Systèmes de délivrance contrôlée et/ou ciblée d’actifs thérapeutiques (nanoparticules, hydrogels, microparticules)
  • Formulation d’agents de contraste pour l’imagerie médicale et plateformes théranostiques
  • Décontamination contre les toxiques
  • Synthèse, caractérisations physico-chimiques, évaluation in vitro et in vivo sur petit animal

Domaines de recherche

Sciences pharmaceutiques

Publications

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Publications

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Smart zwitterionic biodegradable hydrogel for sustained peptide delivery: Application to the neurotherapeutic peptide NX210c

Elise Rosson , Eloise Thomas , Jacqueline Sidi-Boumedine , David Kryza , Marie Couderc et al.

Biomaterials Advances, 2026, 178, pp.214437. ⟨10.1016/j.bioadv.2025.214437⟩

Article dans une revue hal-05291454v1
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Focus on therapeutic peptides and their delivery

Elise Rosson , François Lux , L. David , Yann Godfrin , Olivier Tillement et al.

International Journal of Pharmaceutics, 2025, 675, pp.125555. ⟨10.1016/j.ijpharm.2025.125555⟩

Article dans une revue (article de synthèse) hal-05078046v1
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Functionalization of chitosan with a polycarboxylic macrocycle yields injectable hydrogel with pH and salts responsiveness

Arthur Durand , Thomas Gréa , Gabin Lebeau , Guillaume Jacquot , Augustin Tillement et al.

Materials Today Advances, 2025, 25, pp.100565. ⟨10.1016/j.mtadv.2025.100565⟩

Article dans une revue hal-04967331v1
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Tailor-Made Synthesis of Cerium Oxide Nanoparticles for Improving the Skin Decontamination of Paraoxon

Eloise Thomas , Stephanie Briancon , Frédéric Chaput , Greta Camilla Magnano , Isabelle Trenque et al.

ACS Applied Nano Materials, 2024, 7, pp.16052-16065. ⟨10.1021/acsanm.4c01830⟩

Article dans une revue hal-04672854v1

Anti-Netrin-1 decorated nanoparticles combined with chemotherapy for the treatment of triple-negative breast cancer

Silvia Breusa , Eloise Thomas , Noemi Baldinotti , Serena Zilio , Jean-Guy Delcros et al.

Biomaterials Advances, 2024, 161, pp.213881. ⟨10.1016/j.bioadv.2024.213881⟩

Article dans une revue hal-04577330v1
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CeO2-based peelable gel for neutralization and skin decontamination toward chemical warfare agents

Eloise Thomas , Claire Bordes , Fréderic Chaput , Delphine Arquier , Stéphanie Briançon et al.

Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2024, 687, pp.133520. ⟨10.1016/j.colsurfa.2024.133520⟩

Article dans une revue hal-04480655v1
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Combating lead and cadmium exposure with an orally administered chitosan-based chelating polymer

Jordyn Ann Howard , Halyna Kuznietsova , Natalia Dziubenko , Axel Aigle , Marco Natuzzi et al.

Scientific Reports, 2023, 13 (1), pp.2215. ⟨10.1038/s41598-023-28968-4⟩

Article dans une revue hal-04209149v1
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Subcutaneous Administration of a Zwitterionic Chitosan‐Based Hydrogel for Controlled Spatiotemporal Release of Monoclonal Antibodies

Thomas Gréa , Guillaume Jacquot , Arthur Durand , Clélia Mathieu , Adeline Gasser et al.

Advanced Materials, 2023, 36 (13), pp.2308738. ⟨10.1002/adma.202308738⟩

Article dans une revue hal-04728163v1
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Anti-BCMA Immuno-NanoPET Radiotracers for Improved Detection of Multiple Myeloma

Eloise Thomas , Clélia Mathieu , Patricia Moreno‐gaona , Vincent Mittelheisser , François Lux et al.

Advanced Healthcare Materials, 2021, pp.2101565. ⟨10.1002/adhm.202101565⟩

Article dans une revue hal-03469640v1

3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation

Irini Skaripa-Koukelli , David Hauton , John Walsby-Tickle , Eloise Thomas , Joshua Owen et al.

Cancer & metabolism, 2021, 9 (1), ⟨10.1186/s40170-021-00273-6⟩

Article dans une revue hal-03379071v1
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Feasibility study and direct extraction of endogenous free metallic cations combining hemodialysis and chelating polymer

Marco Natuzzi , Coralie Grange , Thomas Gréa , Thomas Brichart , Axel Aigle et al.

Scientific Reports, 2021, 11 (1), ⟨10.1038/s41598-021-99462-y⟩

Article dans une revue hal-03379081v1

Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation

Joshua Owen , Eloise Thomas , Jyothi Menon , Michael Gray , Irini Skaripa-Koukelli et al.

Journal of Controlled Release, 2020, 319, pp.222-233. ⟨10.1016/j.jconrel.2019.12.045⟩

Article dans une revue hal-02547889v1
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Functionalization of theranostic AGuIX® nanoparticles for PET/MRI/optical imaging

Vivek Thakare , Vu-Long Tran , Marco Natuzzi , Eloise Thomas , Mathieu Moreau et al.

RSC Advances, 2019, 9 (43), pp.24811-24815. ⟨10.1039/C9RA00365G⟩

Article dans une revue hal-02287597v1
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Multimodal AGuIX® Nanoparticles: Size Characterization by HF5 and Optimization of the Radiolabeling with Various SPECT/PET/Theranostic Tracers

S. Huclier-Markai , E. Ntsiba , Eloise Thomas , C. Alliot , Cs Cutler et al.

Int.J.Med.Nano Res., 2019, 6 (1), pp.027. ⟨10.23937/2378-3664.1410027⟩

Article dans une revue hal-02317372v1
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AGuIX® from bench to bedside—Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine

François Lux , Vu Long Tran , Eloise Thomas , Sandrine Dufort , Fabien Rossetti et al.

British Journal of Radiology, 2019, 92 (1093), pp.20180365. ⟨10.1259/bjr.20180365⟩

Article dans une revue (article de synthèse) hal-01935540v1

Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Irini Skaripa-Koukelli , Sheena Wallington et al.

Theranostics, 2019, 9 (19), pp.5595-5609. ⟨10.7150/thno.34669⟩

Article dans une revue hal-02287691v1
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Ultrasmall Silica-Based Bismuth Gadolinium Nanoparticles for Dual Magnetic Resonance–Computed Tomography Image Guided Radiation Therapy

Alexandre Detappe , Eloise Thomas , Mark W Tibbitt || , Sijumon Kunjachan , Oksana Zavidij et al.

Nano Letters, 2017, 17 (3), pp.1733 - 1740. ⟨10.1021/acs.nanolett.6b05055⟩

Article dans une revue hal-01689566v1
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Proton MR spectroscopy and diffusion MR imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma

Magali Toussaint , Sophie Pinel , Florent Auger , Nicolas Durieux , Magalie Thomassin et al.

Theranostics, 2017, 7 (2), pp.436-451. ⟨10.7150/thno.17218⟩

Article dans une revue hal-01399256v1
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68 Ga-radiolabeled AGuIX nanoparticles as dual-modality imaging agents for PET/MRI-guided radiation therapy

Penelope Bouziotis , Dimitris Stellas , Eloise Thomas , Charles Truillet , Charalampos Tsoukalas et al.

Nanomedicine, 2017, 12 (13), pp.1561 - 1574. ⟨10.2217/nnm-2017-0032⟩

Article dans une revue hal-01689547v1
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Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma

Eloise Thomas , Ludovic Colombeau , Mickaël Gries , Thibaut Peterlini , Clélia Mathieu et al.

International Journal of Nanomedicine, 2017, 12, pp.7075-7088. ⟨10.2147/IJN.S141559⟩

Article dans une revue hal-01643075v1

Synthesis and Characterization of 89 Zr-Labeled Ultrasmall Nanoparticles

Charles Truillet , Eloise Thomas , François Lux , Loc T Huynh , Olivier Tillement et al.

Molecular Pharmaceutics, 2016, 13 (7), pp.2596 - 2601. ⟨10.1021/acs.molpharmaceut.6b00264⟩

Article dans une revue hal-01405878v1
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Long-Term in Vivo Clearance of Gadolinium-Based AGuIX Nanoparticles and Their Biocompatibility after Systemic Injection

Lucie Sancey , Shady Kotb , Charles Truillet , F. Appaix , Arthur Marais et al.

ACS Nano, 2015, 9 (3), pp.2477-2488. ⟨10.1021/acsnano.5b00552⟩

Article dans une revue hal-01207383v1

Zwitterionic Biodegradable Hydrogels for Sustained Therapeutic Peptide Delivery

Elise Rosson , Eloise Thomas , Alexandra Weber , Jacqueline Taleb Sidi-Boumedine , David Kryza et al.

Nanohybrid XXI, May 2025, Porquerolles, France

Communication dans un congrès hal-05078087v1

Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies

Elise Rosson , François Lux , Alexandra Weber , Jacqueline Sidi Boumedine , David Kryza et al.

Advanced Drug and Gene Delivery Systems symposium, Jan 2025, Lyon, France

Communication dans un congrès hal-04924331v1

Imagerie K-edge couleur par SPCCT avec des éléments à Z élevé pour l’imagerie fonctionnelle du poumon : étude fantôme.

Agnieszka Gutwinska , Derick Rosario , Antoine Robert , Eloise Thomas , Amanda Pang et al.

Journée Francophone de Radiologie 2025, Oct 2025, Paris, France

Communication dans un congrès hal-05370902v1

Biodegradable hydrogel for sustained release of therapeutic peptide

Elise Rosson , Eloise Thomas , François Lux , Alexandra Weber , Jacqueline Sidi-Boumedine et al.

Nanohybrid XX, May 2024, Bastia, France

Communication dans un congrès hal-04694239v1

Biodegradable hydrogel for sustained release of therapeutic peptide for the treatment of neurological pathologies

Elise Rosson , François Lux , Alexandra Weber , Jacqueline Sidi Boumedine , David Kryza et al.

BNLF 2024 CRS meeting, BNLF local chapter CRS, Oct 2024, Ghent, Belgium

Communication dans un congrès hal-04765505v1

Peptide formulation and development of a novel delivery system for the treatment of neurological pathologie

Elise Rosson , Eloise Thomas , François Lux , Alexandra Weber , Thomas Brichart et al.

Nanohybrides XIX, May 2023, Porquerolles, France

Communication dans un congrès hal-04691977v1

Towards the Synthesis and Delivery of Halogenated MCT1 Substrates

Irini Skaripa-Koukelli , John Walsby-Tickle , Joshua Owen , Eloise Thomas , James Mccullagh et al.

Oncological Drug Delivery Conference, Sep 2019, Oxford, United Kingdom

Communication dans un congrès hal-03989472v1

Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy

Katherine A. Vallis , Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington et al.

Annual Congress of the European Association of Nuclear Medicine, Oct 2019, Barcelona, Spain. pp.1-952, ⟨10.1007/s00259-019-04486-2⟩

Communication dans un congrès hal-02548480v1

Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma

Noémie Thomas , Mickaël Gries , Ludovic Colombeau , Eloise Thomas , Cédric Boura et al.

International Conference on Porphyrins and Phthalocyanines, ICCP-10, Jul 2018, Munich, Germany

Communication dans un congrès hal-01845326v1

AGuIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors

Ludovic Colombeau , Eloise Thomas , Noémie Thomas , Muriel Barberi-Heyob , François Lux et al.

17th Congress of the European Society for Photobiology, Sep 2017, Pise, Italy

Communication dans un congrès hal-02550754v1

Functionalization of AGuIX nanoparticles for improved radiotherapy

Eloise Thomas , Alexandre Detappe , Ross Berbeco , François Lux , Olivier Tillement

Nano-Hybrides n°14, May 2017, Bastia, France

Communication dans un congrès hal-02548188v1

Vascular targeting for the treatment of glioblastoma by PDT

Céline Frochot , Ludovic Colombeau , Eloise Thomas , Régis Vanderesse , Magali Toussaint et al.

16th International Photodynamic Association World Congress, IPA 2017, Jun 2017, Coimbra, Portugal

Communication dans un congrès hal-03243053v1

Gadolinium-based nanoparticles for the treatment of glioblastoma by MRI-guided photodynamic therapy

Eloise Thomas , Magali Toussaint , Ludovic Colombeau , Mickaël Gries , Thibaut Peterlini et al.

World Molecular Imaging Congress, WMIC 2017, Sep 2017, Philadelphia, United States

Communication dans un congrès hal-02548177v1

Use of MR Imaging and proton MR Spectroscopy imaging monitoring to predict tumor response to interstitial photodynamic therapy for glioblastoma

Magali Toussaint , Florent Auger , Sophie Pinel , Magalie Thomassin , Eloise Thomas et al.

Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France

Communication dans un congrès hal-01407476v1

Interstitial photodynamic therapy for glioblastoma: interest of MRI monitoring to predict iPDT effects.

Magali Toussaint , Florent Auger , Sophie Pinel , Nicolas Durieux , Magalie Thomassin et al.

13e Colloque Nano-hybrides, ILM, Lyon 1, May 2016, Porquerolles, France

Communication dans un congrès hal-01312929v1

Ultrasmall nanoparticles functionalization for PET and SPECT imaging

Eloise Thomas , François Lux , Olivier Tillement

Nano-Hybrides n°12, May 2015, Bastia, France

Communication dans un congrès hal-02548199v1

Development of new synthesis protocol and advanced characterization of AGuIX Nanoparticle

Vu Long Tran , Arthur Marais , Eloise Thomas , Cédric Louis , François Lux et al.

ITN-ARGENT, Nov 2015, Obergurgl, Austria

Communication dans un congrès hal-03989480v1

AGuIX nanoparticles for PET/MRI

François Lux , Lucie Sancey , Eloise Thomas , Olivier Tillement

France Life Imaging, Dec 2014, Lyon, France

Communication dans un congrès hal-02548210v1

Development of Tungsten-based contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.

European Molecular Imaging Meeting, Mar 2025, Bilbao, Spain

Poster de conférence hal-05078095v1

Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.

SF Nano, Dec 2024, Toulouse, France

Poster de conférence hal-04924322v1

Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification

Solène Fukuhara , C. Charcosset , Eloise Thomas

BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium

Poster de conférence hal-04765479v1

Biodegradable hydrogel for sustained release of therapeutic peptide

Elise Rosson , Eloise Thomas , Alexandra Weber , Jacqueline Sidi-Boumedine , David Kryza et al.

PBP world meeting (Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology), Mar 2024, Vienne (AUT), Austria

Poster de conférence hal-04694250v1

Preparation of nanoemulsion encapsulating sensitive biomacromolecule by premix membrane emulsification

Solène Fukuhara , C. Charcosset , Eloise Thomas

SF Nano, Dec 2024, Toulouse, France

Poster de conférence hal-04924327v1

Development of metal loaded nanoparticles as contrast agents for Spectral Photon counting computed Tomography (SPCCT) scanner

Priusha Ravipati , Yves Chevalier , Agnieszka Gutwinska , Salim Si-Mohamed , Stephanie Briancon et al.

BNLF 2024 CRS meeting, Oct 2024, Ghent, Belgium

Poster de conférence hal-04765470v1

CeO2-based peelable gel for neutralization and skin decontamination toward chemical warefare agent simulants

Eloise Thomas , Delphine Arquier , C. Barratier , Claire Bordes , Fréderic Chaput et al.

Formula XI, Jul 2023, Lille, France

Poster de conférence hal-04462743v1

Monoclonal antibodies decorated nanoparticles for the treatment of triple negative breast cancer

Silvia Breusa , Jean‐guy Delcros , Eloise Thomas , Serena Zilio , Diana Marcela Hernandez Palomino et al.

SFNano Annual Meeting, Dec 2022, Strasbourg, France

Poster de conférence hal-03989500v1

Ultrasound-Mediated Cavitation To Enhance The Delivery Of Liposomal Formulations For Targeted Radionuclide Therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington , Michael Gray et al.

Controlled Release Society Annual Meeting, Jul 2019, Valencia, Spain

Poster de conférence hal-02548225v1

Ultrasound And Microbubbles Enhance The Delivery Of A Liposomal Formulation For Targeted Chemo-Radionuclide Therapy

Eloise Thomas , Jyothi Menon , Joshua Owen , Sheena Wallington , Michael Gray et al.

British Nuclear Medicine Society Spring Meeting, Apr 2019, Oxford, United Kingdom

Poster de conférence hal-02548236v1

Indium-111 afterloading of preformed EGF containing liposomes for molecularly targeted radionuclide delivery via ultrasound induced cavitation.

Joshua Owen , Jyothi Menon , Eloise Thomas , Irini Skaripa-Koukelli , Martin Gill et al.

Annual Congress of the European Association of Nuclear Medicine, Oct 2018, Düsseldorf, Germany. European Journal of Nuclear Medicine and Molecular Imaging, 45 (S1), pp.1-844, 2019, ⟨10.1007/s00259-018-4148-3⟩

Poster de conférence hal-02548464v1

Targeted and combined chemo-radionucleide therapy for the treatment of breast cancers

Eloise Thomas , Jyothi Menon , Joshua Owen , Irini Skaripa-Koukelli , Robert Carlisle et al.

CRUK Symposium, Jun 2018, Oxford, United Kingdom

Poster de conférence hal-02548247v1

Silica-Based Bismuth-Gadolinium Nanoparticles for MRI and CT Image-Guided Radiation Therapy

Alexandre Detappe , Eloise Thomas , M. Tibbitt , S. Kunjachan , O. Zavidij et al.

ASTRO annual meeting, Sep 2017, San Diego, United States

Poster de conférence hal-03989491v1

Radiolabeling for long term biodistribution of ultrasmall nanoparticles designed for radiotherapy guided by MRI

Eloise Thomas , Charles Truillet , Franck Denat , François Lux , Frederic Boschetti et al.

World Molecular Imaging Congress, Sep 2016, New-York, United States

Poster de conférence hal-02548258v1

PET and MR imaging with 64Cu/68Ga-labeled AGuIX ultra-small nanoparticles in tumor-bearing mice

Marie-Caline Abadjian , Eloise Thomas , Joseph Latoche , Lesley Foley , Kathryn Day et al.

SNMMI Annual Meeting, Jun 2016, San Diego, United States. 57 (Supplement2), pp.1181, 2016

Poster de conférence hal-02548345v1

AGUIX® theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of brain tumors

Ludovic Colombeau , Eloise Thomas , Thibaut Peterlini , Mickaël Gries , Noémie Thomas et al.

Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , 17, pp.A71, 2017, ⟨10.1016/j.pdpdt.2017.01.161⟩

Poster de conférence istex hal-01408883v1

Ultrasmall gadolinium-based nanoparticles designed for photodynamic therapy (PDT) guided by MRI

E Thomas , M Toussaint , Ludovic Colombeau , Céline Frochot , Régis Vanderesse et al.

Photodynamic Therapy and Photodiagnosis update, Oct 2016, Nancy, France. , Photodiagnosis and Photodynamic Therapy, 17, pp.A60, 2017, ⟨10.1016/j.pdpdt.2017.01.136⟩

Poster de conférence hal-01498485v1

Functionalization of ultrasmall nanoparticles for theranosctic applications

Eloise Thomas , Frederic Boschetti , Franck Denat , François Lux , Olivier Tillement

COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2015, Belgrade, Serbia

Poster de conférence hal-02548269v1

AGuIX modifications for active tumor targeting and radiolabelling

Eloise Thomas , Charles Truillet , Marie Plissonneau , Frederic Boschetti , Franck Denat et al.

COST TD1004 Action Theranostics Imaging and Therapy: An Action to Develop Novel Nanosized Systems for Imaging-Guided Drug Delivery, Oct 2014, Istanbul, Turkey

Poster de conférence hal-02548293v1