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Retinal atrophy, inflammation, phagocytic and metabolic disruptions develop in the MerTK-cleavage-resistant mouse model
Julie Enderlin
,
Quentin Rieu
,
Salomé Réty
,
Elora M Vanoni
,
Solène Roux
et al.
Article dans une revue
hal-04563541
v1
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Gas6 and Protein S Ligands Cooperate to Regulate MerTK Rhythmic Activity Required for Circadian Retinal Phagocytosis
Célia Parinot
,
Jonathan Chatagnon
,
Quentin Rieu
,
Solène Roux
,
Dorine Néel
et al.
Article dans une revue
inserm-04799289
v1
|
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Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration. Ablation of primary cilia exclusively in the RPE leads to retinal degeneration and visual impairment
Viola Kretschmer
,
Sandra Schneider
,
Peter A. Matthiessen
,
Dominik Reichert
,
Nathan Hotaling
et al.
Article dans une revue
inserm-04292959
v1
|
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Pleiotropic Roles of Scavenger Receptors in Circadian Retinal Phagocytosis: A New Function for Lysosomal SR-B2/LIMP-2 at the RPE Cell Surface
Quentin Rieu
,
Antoine Bougoüin
,
Yvrick Zagar
,
Jonathan Chatagnon
,
Abdallah Hamieh
et al.
Article dans une revue
inserm-03814298
v1
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Modeling PRPF31 retinitis pigmentosa using retinal pigment epithelium and organoids combined with gene augmentation rescue
Amélie Rodrigues
,
Amélie Slembrouck-Brec
,
Céline Nanteau
,
Angélique Terray
,
Yelyzaveta Tymoshenko
et al.
Article dans une revue
hal-03774125
v1
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Lack of the antioxidant enzyme methionine sulfoxide reductase A in mice impairs RPE phagocytosis and causes photoreceptor cone dysfunction
Francesca Mazzoni
,
Ying Dun
,
Jade A Vargas
,
Emeline Nandrot
,
Silvia C Finnemann
Article dans une revue
hal-03163479
v1
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A Splice Variant in SLC16A8 Gene Leads to Lactate Transport Deficit in Human iPS Cell-Derived Retinal Pigment Epithelial Cells
Laurence Klipfel
,
Marie Cordonnier
,
Léa Thiébault
,
Emmanuelle Clérin
,
Frédéric Blond
et al.
Article dans une revue
hal-03131049
v1
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Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells
Alvaro Plaza Reyes
,
Sandra Petrus-Reurer
,
Sara Padrell Sánchez
,
Pankaj Kumar
,
Iyadh Douagi
et al.
Article dans une revue
inserm-02648422
v2
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Preclinical safety studies of human embryonic stem cell‐derived retinal pigment epithelial cells for the treatment of age‐related macular degeneration
Sandra Petrus-Reurer
,
Pankaj Kumar
,
Sara Padrell Sánchez
,
Monica Aronsson
,
Helder André
et al.
Article dans une revue
hal-03086697
v1
|
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Cohen Syndrome-Associated Cataract Is Explained by VPS13B Functions in Lens Homeostasis and Is Modified by Additional Genetic Factors
Vincent Lhussiez
,
Elisabeth Dubus
,
Quénol Cesar
,
Niyazi Acar
,
Emeline F Nandrot
et al.
Article dans une revue
hal-02969762
v1
|
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Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation
Sara Touhami
,
Fanny Beguier
,
Sébastien Augustin
,
Hugo Charles-Messance
,
Lucile Vignaud
et al.
Article dans une revue
inserm-01736588
v1
|
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Collectin-11 Is an Important Modulator of Retinal Pigment Epithelial Cell Phagocytosis and Cytokine Production
Xia Dong
,
Weiju Wu
,
Liang Ma
,
Chengfei Liu
,
Mohajeet B Bhuckory
et al.
Article dans une revue
hal-03086718
v1
|
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Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions
Sacha Reichman
,
Amélie Slembrouck
,
Giuliana Gagliardi
,
Antoine Chaffiol
,
Angélique Terray
et al.
Article dans une revue
hal-01480587
v1
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Otx2- genetically modified retinal pigment epithelial cells rescue photoreceptors after transplantation
Christo Kole
,
Laurence Klipfel
,
Ying Yang
,
Vanessa Ferracane
,
Frédéric Blond
et al.
Article dans une revue
hal-01611959
v1
|
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Cleavage of Mer Tyrosine Kinase (MerTK) from the Cell Surface Contributes to the Regulation of Retinal Phagocytosis
Ah-Lai Law
,
Célia Parinot
,
Jonathan Chatagnon
,
Basile Gravez
,
José-Alain Sahel
et al.
Article dans une revue
hal-03086745
v1
|
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From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium
Sacha Reichman
,
Angélique Terray
,
Amélie Slembrouck
,
Céline Nanteau
,
Gaël Orieux
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111, pp.8518 - 8523. ⟨10.1073/pnas.1324212111⟩
Article dans une revue
hal-03086749
v1
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Large-Scale Purification of Porcine or Bovine Photoreceptor Outer Segments for Phagocytosis Assays on Retinal Pigment Epithelial Cells
Célia Parinot
,
Quentin Rieu
,
Jonathan Chatagnon
,
Silvia C. Finnemann
,
Emeline F. Nandrot
Journal of visualized experiments : JoVE, 2014
Article dans une revue
hal-03086746
v1
|
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Mutations in Pre-mRNA Processing Factors 3, 8, and 31 Cause Dysfunction of the Retinal Pigment Epithelium
Michael H Farkas
,
Deborah S Lew
,
Maria E Sousa
,
Kinga Bujakowska
,
Jonathan Chatagnon
et al.
Article dans une revue
hal-03086747
v1
|
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CCR2(+) monocytes infiltrate atrophic lesions in age-related macular disease and mediate photoreceptor degeneration in experimental subretinal inflammation in Cx3cr1 deficient mice.
Florian Sennlaub
,
Constance Auvynet
,
Bertrand Calippe
,
Sophie Lavalette
,
Lucie Poupel
et al.
Article dans une revue
inserm-00912837
v1
|
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Disease-Causing Mutations in BEST1 Gene Are Associated with Altered Sorting of Bestrophin-1 Protein
Jordan A. Doumanov
,
Christina Zeitz
,
Paloma Dominguez Gimenez
,
Isabelle Audo
,
Abhay Krishna
et al.
Article dans une revue
hal-01583466
v1
|
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Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin
Emeline Nandrot
,
Kathryn E Silva
,
Christina Scelfo
,
Silvia C Finnemann
Article dans une revue
hal-03086754
v1
|
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The Signalling Role of the αvβ5-Integrin Can Impact the Efficacy of AAV in Retinal Gene Therapy
Thérèse Cronin
,
Daniel Chung
,
Ying Yang
,
Emeline Nandrot
,
Jean Bennett
Article dans une revue
inserm-02894109
v1
|
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Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin
Chia-Chia Yu
,
Emeline Nandrot
,
Ying Dun
,
Silvia C Finnemann
Article dans une revue
hal-03086755
v1
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Three Gene-Targeted Mouse Models of RNA Splicing Factor RP Show Late-Onset RPE and Retinal Degeneration
John J. Graziotto
,
Michael Farkas
,
Kinga Bujakowska
,
Bertrand M. Deramaudt
,
Qi Zhang
et al.
Investigative Ophthalmology & Visual Science, 2011
Article dans une revue
hal-03086760
v1
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In vitro differentiation of retinal pigment epithelium from adult retinal stem cells
Claudia Aruta
,
Francesca Giordano
,
Anna de Marzo
,
Antonella Comitato
,
Graça Raposo
et al.
Article dans une revue
istex
hal-03086757
v1
|
|
EYS is a major gene for rod-cone dystrophies in France
Isabelle Audo
,
José-Alain Sahel
,
Saddek Mohand-Saïd
,
Marie-Elise Lancelot
,
Aline Antonio
et al.
Article dans une revue
hal-00552377
v1
|
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TRPM1 Is Mutated in Patients with Autosomal-Recessive Complete Congenital Stationary Night Blindness
Isabelle Audo
,
Susanne Kohl
,
Bart P Leroy
,
Francis L Munier
,
Xavier Guillonneau
et al.
Article dans une revue
hal-03086762
v1
|
|
Lack of v 5 Integrin Receptor or Its Ligand MFG-E8: Distinct Effects on Retinal Function
Emeline F. Nandrot
,
Silvia C. Finnemann
Ophthalmic Research, 2008
Article dans une revue
hal-03086766
v1
|
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Essential role for MFG-E8 as ligand for ␣v5 integrin in diurnal retinal phagocytosis
Emeline Nandrot
,
Monika Anand
,
Dena Almeida
,
Kamran Atabai
,
Dean Sheppard
et al.
Proceedings of the National Academy of Sciences of the United States of America, 2007
Article dans une revue
hal-03086772
v1
|
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Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak
Emeline F. Nandrot
,
Monika Anand
,
Mousumi Sircar
,
Silvia C. Finnemann
American Journal of Physiology - Cell Physiology, 2006
Article dans une revue
hal-03086780
v1
|
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Retinal cell type expression specificity of HIV-1-derived gene transfer vectors upon subretinal injection in the adult rat: influence of pseudotyping and promoter.
Alexis-Pierre Bemelmans
,
Sébastien Bonnel
,
Leila Houhou
,
Noëlle Dufour
,
Emeline Nandrot
et al.
Article dans une revue
hal-00187439
v1
|
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Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking alphavbeta5 Integrin
Emeline F. Nandrot
,
Yoonhee Kim
,
Scott E. Brodie
,
Xiaozhu Huang
,
Dean Sheppard
et al.
Journal of Experimental Medicine, 2004
Article dans une revue
hal-03086798
v1
|
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Identification of novel genes and altered signaling pathways in the retinal pigment epithelium during the Royal College of Surgeons rat retinal degeneration
Eric M. Dufour
,
Emeline Nandrot
,
Dominique Marchant
,
Loic van den Berghe
,
Stéphanie Gadin
et al.
Neurobiology of Disease, 2003, pp.166-180
Article dans une revue
hal-03086809
v1
|
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Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts
Emeline Nandrot
,
Christine Slingsby
,
A Basak
,
M Cherif-Chefchaouni
,
B Benazzouz
et al.
Journal of Medical Genetics, 2003
Article dans une revue
hal-03086814
v1
|
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Evidence of clinical and genetic heterogeneity in autosomal dominant congenital cerulean cataracts
Latifa Hilal
,
Emeline Nandrot
,
Mohamed Belmekki
,
Siham El Bacha
,
Mohamed Chefchaouni
et al.
Ophthalmic Genetics, 2002
Article dans une revue
hal-03086816
v1
|
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Homozygous Deletion in the Coding Sequence of the c-mer Gene in RCS Rats Unravels General Mechanisms of Physiological Cell Adhesion and Apoptosis
Emeline Nandrot
,
Eric Dufour
,
Alexandra C Provost
,
Marie O Péquignot
,
Sébastien Bonnel
et al.
Article dans une revue
istex
hal-03086817
v1
|