Frédéric Bigey

Research Scientist, INRAE, France
40 %
Libre accès
98
Documents
Affiliations actuelles
  • Sciences Pour l'Oenologie (SPO)
  • Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)
Contact

Présentation

I am a research scientist specializing in yeast genomics and bioinformatics, with a focus on the comparative genomics of yeasts associated with food processes. My expertise lies in bioinformatics and computational biology, particularly in sequence analysis of industrial yeast genomes and in comparative genomics of yeasts from both technological and natural habitats.

In 2025, I was the first author of a comparative genomics study of the yeast Monosporozyma unispora (FEMS Yeast Research, DOI: 10.1093/femsyr/foaf016). This research highlighting their genetic diversity, adaptive traits, and relevance for both evolutionary studies and emerging biotechnological applications.

In 2024, I was the first author of a study on the genomic, genetic and phenotypic landscape of Candida anglica yeast population isolated from french PDO cheeses (Food Microbiology, DOI: 10.1016/j.fm.2024.104584). This work investigated how domestication and adaptation to this specific environment have shaped their genomic signatures, thereby informing our understanding of evolutionary processes.

In 2023, I was the first author of a comparative study of the oleagenous yeast Yarrowia lipolytica (Journal of Fungi, 9:76; DOI: 10.3390/jof9010076). With my colleagues I investigated 56 natural isolates and demonstrated that this species exhibits low genetic diversity, with a pan-genome closely resembling the core genome, suggesting a relatively recent evolutionary trajectory. Despite this, we observed substantial phenotypic diversity among strains, particularly regarding lipid metabolism.

In 2021, I was the first author of a study on the domestication of bakery yeast (Current Biology, 31:1–12; DOI: 10.1016/j.cub.2020.11.016). This work focused on Saccharomyces cerevisiae strains used in bread-making and revealed that domestication has been accompanied by dispersion, hybridization, and divergent selection processes, shaped differently by industrial and artisanal practices.

Earlier, in 2009, I co-authored the genome sequence analysis of the first wine yeast strain Saccharomyces cerevisiae EC1118 (PNAS, 106:16333–16338; DOI: 10.1073/pnas.0904673106), which uncovered unprecedented eukaryote-to-eukaryote horizontal gene transfer events. This study shed light on the genomic innovations that have contributed to the adaptation of S. cerevisiae wine strains to fermentation environments.

Collectively, my research integrates genomic sequencing, bioinformatics, and comparative evolutionary analyses to better understand yeast diversity, adaptation, and domestication, with direct implications for biotechnology and food fermentation processes.


Compétences

Yeast genomics Yeast population genomics Computational biology

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Publications

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Insights into the genomic and phenotypic diversity of Monosporozyma unispora strains isolated from anthropic environments

Frédéric Bigey , Xavière Menatong Tene , Marc Wessner , Hugo Devillers , Martine Pradal et al.

FEMS Yeast Research, 2025, 25, pp.foaf016. ⟨10.1093/femsyr/foaf016⟩

Article dans une revue cea-05047166v1
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Differential adaptation of the yeast Candida anglica to fermented food

Frédéric Bigey , Xavière Menatong Tene , Marc Wessner , Martine Pradal , Jean-Marc Aury et al.

Food Microbiology, 2024, 123, pp.104584. ⟨10.1016/j.fm.2024.104584⟩

Article dans une revue hal-04646352v1
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Microbial Dynamics during labneh Ambaris Production in Earthenware Jars

Reine Abi Khalil , Christel Couderc , Sophie Yvon , Delphine Sicard , Frédéric Bigey et al.

Foods, 2023, 12 (16), pp.3131. ⟨10.3390/foods12163131⟩

Article dans une revue hal-04197014v1
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Insights into the Genomic and Phenotypic Landscape of the Oleaginous Yeast Yarrowia lipolytica

Frédéric Bigey , Emilie Pasteur , Xymena Połomska , Stéphane Thomas , Anne-Marie A.-M. Crutz-Le Coq et al.

Journal of Fungi, 2023, 9 (1), pp.76. ⟨10.3390/jof9010076⟩

Article dans une revue hal-03942758v1
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Microbial communities and main features of labneh Ambaris, a traditional Lebanese fermented goat milk product

Reine Abi Khalil , Sophie Yvon , Christel Couderc , Loubnah Belahcen , Gwenaelle Jard et al.

Journal of Dairy Science, 2022, 106 (2), pp.868-883. ⟨10.3168/jds.2022-22275⟩

Article dans une revue hal-03922548v1
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Artisanal Household Milk Pasteurization Is Not a Determining Factor in Structuring the Microbial Communities of Labneh Ambaris: A Pilot Study

Reine Abi Khalil , Christel Couderc , Sophie Yvon , Gwenaelle Jard , Delphine Sicard et al.

Foods, 2022, 11 (23), pp.3874. ⟨10.3390/foods11233874⟩

Article dans une revue hal-03880546v1
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Evidence for Two Main Domestication Trajectories in Saccharomyces cerevisiae Linked to Distinct Bread-Making Processes

Frédéric Bigey , Diego Segond , Anne Friedrich , Stephane Guezenec , Aurélie Bourgais et al.

Current Biology, 2021, 31, pp.722-732. ⟨10.1016/j.cub.2020.11.016⟩

Article dans une revue hal-03110131v1
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The yeast mating-type switching endonuclease HO is a domesticated member of an unorthodox homing genetic element family

Aisling Coughlan , Lisa Lombardi , Stephanie Braun-Galleani , Alexandre Ar Martos , Frederic Bigey et al.

eLife, 2020, 9, ⟨10.7554/eLife.55336⟩

Article dans une revue hal-02890164v1
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Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae

Catherine Tesniere , Chloé Bessiere , Martine Pradal , Isabelle Sanchez , Bruno Blondin et al.

PLoS ONE, 2019, 14 (4), ⟨10.1371/journal.pone.0215870⟩

Article dans une revue hal-02126102v1
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Genome sequence of Torulaspora microellipsoides CLIB 830T

Virginie Galeote , Frederic Bigey , Hugo Devillers , Sylvie Dequin , Kenneth Wolfe et al.

Genome Announcements, 2018, 6 (26), ⟨10.1128/genomeA.00615-18⟩

Article dans une revue hal-02623200v1
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Adaptation of S. cerevisiae to Fermented Food Environments Reveals Remarkable Genome Plasticity and the Footprints of Domestication

Jean-Luc Legras , Virginie Galeote , Frederic Bigey , Carole Camarasa , Souhir Marsit et al.

Molecular Biology and Evolution, 2018, 35 (7), pp.1712-1727. ⟨10.1093/molbev/msy066⟩

Article dans une revue hal-01837856v1
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Relief from nitrogen starvation triggers transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells

Catherine Tesniere , Martine Pradal , Chloé Bessiere , Isabelle Sanchez , Bruno Blondin et al.

Molecular Biology of the Cell, 2018, 29 (4), pp.490-498. ⟨10.1091/mbc.E17-01-0061⟩

Article dans une revue hal-01837842v1
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Genomic signatures of adaptation to wine biological aging conditions in biofilm-forming flor yeasts

Anna Lisa Coi , Frederic Bigey , Sandrine Mallet , Souhir Marsit , G. Zara et al.

Molecular Ecology, 2017, 26 (7), pp.2150-2166. ⟨10.1111/mec.14053⟩

Article dans une revue hal-01608516v1
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Natural yeast promoter variants reveal epistasis in the generation of transcriptional-mediated noise and its potential benefit in stressful conditions.

Jian Liu , Helene Yken , Frederic Bigey , Sylvie Dequin , Jean Marie François et al.

Genome Biology and Evolution, 2015, 7 (4), pp.969-984. ⟨10.1093/gbe/evv047⟩

Article dans une revue hal-01190166v1

Une étude du besoin en azote des levures œnologiques révèle le rôle clé de la signalisation azote dans le contrôle de la vitesse de fermentation

Claire Brice , Isabelle Sanchez , Catherine Tesniere , Frederic Bigey , Jean-Luc Legras et al.

La revue des œnologues et des techniques vitivinicoles et œnologiques, 2015, 154, pp.21-24

Article dans une revue hal-01506449v1
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Evolutionary advantage conferred by an eukaryote-to-eukaryote gene transfer event in wine yeasts

Souhir Marsit , Adriana Mena , Frederic Bigey , Francois Xavier Sauvage , Arnaud Couloux et al.

Molecular Biology and Evolution, 2015, 32 (7), pp.1695-1707. ⟨10.1093/molbev/msv057⟩

Article dans une revue hal-01837744v1

New insights into the adaptation of yeast to anthropic environment using comparative genomics

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

Yeast, 2015, 32, pp.S89-S90. ⟨10.1002/yea.3091⟩

Article dans une revue hal-01837749v1

Intrastrain genomic and phenotypic variability of the commercial Saccharomyces cerevisiae strain Zymaflore VL1 reveals microevolutionary adaptation to vineyard environments

Ricardo Franco-Duarte , Frederic Bigey , Laura Carreto , Inês Mendes , Sylvie Dequin et al.

FEMS Yeast Research, 2015, 15 (6), 13 p. ⟨10.1093/femsyr/fov063⟩

Article dans une revue hal-01837750v1
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A genetic approach of wine yeast fermentation capacity in nitrogen-starvation reveals the key role of nitrogen signaling.

Claire Brice , Isabelle Sanchez , Frederic Bigey , Jean-Luc Legras , Bruno Blondin

BMC Genomics, 2014, 15 (1), pp.495. ⟨10.1186/1471-2164-15-495⟩

Article dans une revue hal-01189979v1
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Genome sequence of the food spoilage Yeast Zygosaccharomyces bailii CLIB 213T.

Virginie Galeote , Frédéric Bigey , Hugo Devillers , Cécile Neuvéglise , Sylvie Dequin

Genome Announcements, 2013, 1 (4), ⟨10.1128/genomeA.00606-13⟩

Article dans une revue hal-01837764v1
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Phenotypic landscape of Saccharomyces cerevisiae during wine fermentation: evidence for origin-dependent metabolic traits

Carole Camarasa , Isabelle Sanchez , Pascale Brial , Frederic Bigey , Sylvie S. Dequin

PLoS ONE, 2011, 6 (9), pp.e25147. ⟨10.1371/journal.pone.0025147⟩

Article dans une revue hal-02645675v1
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Amplification of a Zygosaccharomyces bailii DNA Segment in Wine Yeast Genomes by Extrachromosomal Circular DNA Formation

Virginie Galeote , Frederic Bigey , Emmanuelle Beyne , Maité Novo Molinero , Jean-Luc Legras et al.

PLoS ONE, 2011, 6 (3), ⟨10.1371/journal.pone.0017872⟩

Article dans une revue hal-01222409v1
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Deciphering the molecular basis of wine yeast fermentation traits using a combined genetic and genomic approach

Chloé C. Ambroset , Maud Petit , Christian Brion , Isabelle Sanchez , Pierre Delobel et al.

G3, 2011, 1, pp.263-281. ⟨10.1534/G3.111.000422⟩

Article dans une revue hal-01487358v1
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Eukaryote-to-eukaryote gene transfer events revealed by the genome sequence of the wine yeast Saccharomyces cerevisiae EC1118

Maite Novo , Frederic Bigey , Emmanuelle Beyne , Virginie Galeote , Frédérick Gavory et al.

Proceedings of the National Academy of Sciences of the United States of America, 2009, 106 (38), pp.16333-16338. ⟨10.1073/pnas.0904673106⟩

Article dans une revue hal-02668729v1

Production of a recombinant carotenoid cleavage dioxygenase from grape and enzyme assay in water-miscible organic solvents

Sandrine Mathieu , Frédéric Bigey , Jérôme Procureur , Nancy Terrier , Ziya Günata

Biotechnology Letters, 2007, 29 (5), pp.837-841. ⟨10.1007/s10529-007-9315-8⟩

Article dans une revue istex hal-03763651v1

Overexpression and characterization of two human salivary proline rich proteins

Christine Pascal , Frederic Bigey , Robert Ratomahenina , Helene Boze , Guy Moulin et al.

Protein Expression and Purification, 2006, 47 (2), pp.524-532. ⟨10.1016/j.pep.2006.01.012⟩

Article dans une revue istex hal-02662210v1

A novel lipase / acyltransferase from the yeast Candida albicans: expression and characterisation of the recombinant enzyme

Jean-Louis Roustan , Agustin Rascon Chu , Guy Moulin , Frederic Bigey

Applied Microbiology and Biotechnology, 2005, 68 (2), pp.203-212. ⟨10.1007/s00253-005-1896-3⟩

Article dans une revue istex hal-02681391v1

A Carotenoid Cleavage Dioxygenase from Vitis vinifera L.: functional characterization and expression during grape berry development in relation to C13-norisoprenoid accumulation

Sandrine Mathieu , Nancy Terrier , Jérôme Procureur , Frédéric Bigey , Ziya Günata

Journal of Experimental Botany, 2005, 56 (420), pp.2721-2731. ⟨10.1093/jxb/eri265⟩

Article dans une revue hal-03763658v1

Overexpression of ovine leptin in Pichia pastoris : physiological yeast response to leptin production and characterization of the recombinant hormone

C. Laborde , Patrick Chemardin , Frederic Bigey , Yves Combarnous , Gabrielle Moulin et al.

Yeast, 2004, 21, pp.249-263. ⟨10.1002/yea.1073⟩

Article dans une revue hal-02675023v1

High-level expression of Candida parapsilosis lipase/acyltransferase in Pichia pastoris

Laetitia Brunel , Virginie Neugnot , Laure Landucci , Helene Boze , Guy Moulin et al.

Journal of Biotechnology, 2004, 111 (1), pp.41-50. ⟨10.1016/j.jbiotec.2004.03.007⟩

Article dans une revue istex hal-02166482v1
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Identification of a triacylglycerol lipase gene family in Candida deformans: molecular cloning and functional expression

Frederic Bigey , Karine Tuery , Daisy Bougard , Jean-Marc Nicaud , Guy Moulin

Yeast, 2003, 20 (3), pp.233-248. ⟨10.1002/yea.958⟩

Article dans une revue hal-02165415v1

Transcriptional analysis of the nitrile-degrading operon from Rhodococcus sp. ACV2 and high level production of recombinant amidase with an Escherichia coli-T7 expression system

Frederic Bigey , H. Chebrou , David Fournand , A. Arnaud

Journal of Applied Microbiology, 1999, 86, pp.752-760

Article dans une revue hal-02689034v1

Acyl transfer activity of an amidase from Rhodococcus sp. strain R312: Formation of a wide range of hydroxamic acids

David Fournand , Frederic Bigey , A. Arnaud

Applied and Environmental Microbiology, 1998, 64 (8), pp.2844-2852

Article dans une revue hal-02690089v1

Spectrophotometric assay of aliphatic monohydroxamic acids and alpa-, bêta-, and gamma-aminohydroxamic acids in aqueous medium

David Fournand , J.L. Pirat , Frederic Bigey , A. Arnaud , P. Galzy

Analytica Chimica Acta, 1997, 353, pp.359-366

Article dans une revue hal-02698748v1

Biocatalyst improvement for the production of short-chain hydroxamic acids

David Fournand , Frederic Bigey , Robert Ratomahenina , A. Arnaud , P. Galzy

Enzyme and Microbial Technology, 1997, 20, pp.424-431

Article dans une revue hal-02697464v1

Study of the amidase signature group

H. Chebrou , Frederic Bigey , A. Arnaud , P. Galzy

BBA - Biochimica et Biophysica Acta, 1996, 1298, pp.285-293

Article dans une revue hal-02694915v1

Amide metabolism: a putative ABC transporter in Rhodococcus sp. R312

H. Chebrou , Frederic Bigey , A. Arnaud , P. Galzy

Gene, 1996, 182, pp.215-218

Article dans une revue hal-02691614v1

Karyotype studies on different strains of Candida molischiana by pulsed-field gel electrophoresis

Guilhem Janbon , R. Magnet , Frederic Bigey , A. Arnaud , P. Galzy

Current Genetics, 1995, 28, pp.150-154

Article dans une revue hal-02712941v1

Sizing of the Rhodococcus sp. R312 genome by pulsed-field gel electrophoresis. Localization of genes involved in nitrile degradation

Frederic Bigey , Guilhem Janbon , A. Arnaud , P. Galzy

Antonie van Leeuwenhoek, 1995, 68, pp.173-179

Article dans une revue hal-02714288v1

Brevibacterium linens pBL33 and Rhodococcus rhodochrous pRC1 cryptic plasmids replicate in Rhodococcus sp. R312 (formerly Brevibacterium sp. R312)

Frederic Bigey , B. Grossiord , C.K.N. Chan Kwo Chion , A. Arnaud , P. Galzy

Gene, 1995, 154, pp.77-79

Article dans une revue hal-02710090v1

Application of high-performance liquid chromatography to the study of the biological transformation of adiponitrile

J.L. Moreau , S. Azza , Frederic Bigey , A. Arnaud , P. Galzy

Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 1994, 656, pp.197-202

Article dans une revue hal-02708542v1

The enzymatic production of adipic acid

J.L. Moreau , Frederic Bigey , S. Azza , A. Arnaud , P. Galzy

Biocatalysis and Agricultural Biotechnology, 1994, 10, pp.325-340

Article dans une revue hal-02713293v1

Cloning of the wide spectrum amidase gene from Brevibacterium sp. R312 by genetic complementation. Overexpression in Brevibacterium sp. and Escherichia coli

S. Azza , Frederic Bigey , A. Arnaud , P. Galzy

FEMS Microbiology Letters, 1994, 122, pp.129-136

Article dans une revue hal-02716101v1

The N-terminal amino acid sequences of Brevibacterium sp. R312 nitrile hydratase

Robert Duran , C.K.N.C.K. Chion , F. Bigey , A. Arnaud , P. Galzy

Applied Microbiology and Biotechnology, 1992, 32 (1), pp.13-19. ⟨10.1002/jobm.3620320104⟩

Article dans une revue istex hal-01841807v1

Transformation of whole cells of Brevibacterium SP. R312, a nitrile hydratase producing strain

C.N.K. Chan Kwo Chion , Frederic Bigey , A. Arnaud , P. Galzy

Mededelingen van de Faculteit Landbouwwetenschappen Rijksuniversiteit Gent, 1992, 57 (4b), pp.2089-2091

Article dans une revue hal-02705497v1

Dici: a new Tc1/mariner transposon reshaping the genome of Diutina catenulata

Frédéric Bigey , Cécile Neuveglise

ISSY 38 "Yeast - the omni-tool", Adrianna Skoneczna; Zbigniew Lazar, Sep 2025, Warsaw, Poland

Communication dans un congrès hal-05288044v1

Impacts de la domestication sur le génome des levures S. cerevisiae de vin et de pain

Jean-Luc Legras , Virginie Galeote , Frédéric Bigey , Sylvie Dequin , Delphine Sicard

14. Journées Jean Chevaugeon - Rencontres de Phytopathologie - Mycologie, Jan 2024, Aussois, France

Communication dans un congrès hal-04966875v1

Drivers of microbial communities dynamic in sourdough

Thibault Nidelet , Jennifer Mata-Orozco , Stéphane Guezenec , Thérèse Marlin , Marie-Françoise Samson et al.

Séminaire sur le bilan des recherches sur le palmier à huile au Bénin, Société Française de Microbiologie, Oct 2022, Montpellier, France

Communication dans un congrès hal-04237728v1
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Mycotoxins throughout the life cycle of a wheat grain. A case study of organic farming with on-farm storage and processing

Camille Vindras-Fouillet , Marie-Hélène Robin , François Brionnet , Frédéric Bigey , Delphine Sicard et al.

43. Mycotoxin Workshop, May 2022, Toulouse, France

Communication dans un congrès hal-03727947v1
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How different anthropogenic environments have shaped the genome of S. cerevisiae ?

Virginie Galeote , Jean-Luc Legras , Frederic Bigey , Souhir Marsit , Carole Camarasa et al.

7. Conference on Physiology of Yeast and Filamentous Fungi, Jun 2019, Milan, Italy

Communication dans un congrès hal-02461748v1
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Horizontal gene transfer: one of the key mechanisms involved into the adaptation of yeast to their environment

Virginie Galeote , Jean-Luc Legras , Frederic Bigey , Souhir Marsit , Carole Camarasa et al.

ESF-EMBO Symposium, Comparative genomics of eukaryotic microbes: Genomes in flux, and flux between genomes, Oct 2019, Sant Feliu de Guíxols, Spain

Communication dans un congrès hal-02461750v1

Horizontal Gene Transfer and Introgression: key mechanisms of adaptation of yeast to its ecological niches

Virginie Galeote , Jean-Luc Legras , Souhir Marsit , Frederic Bigey , Carole Camarasa et al.

2. Joint Congress on Evolutionary Biology, Aug 2018, Montpellier, France

Communication dans un congrès hal-01918074v1

Domesticated lineages of S. cerevisiae from fermented food environments present customized genome with selective footprints

Jean-Luc Legras , Virginie Galeote , Frederic Bigey , Anna Lisa Coi , Souhir Marsit et al.

2. Joint Congress on Evolutionary Biology, 2018, Montpellier, France

Communication dans un congrès hal-01918075v1

Adaptation of Yeast to Anthropogenic Environments Using Comparative Genomics

Jean-Luc Legras , Virginie Galeote , Anna Lisa Coi , Frederic Bigey , Souhir Marsit et al.

27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), Aug 2017, Prague, Czech Republic

Communication dans un congrès hal-01608045v1

Horizontal Gene Transfer is a key mechanism permitting adaptation of S. cerevisiae to its ecological niches

Virginie Galeote , Jean-Luc Legras , Frederic Bigey , Souhir Marsit , Carole Camarasa et al.

21. Evolutionary Biology Meeting at Marseilles, 2017, Marseille, France

Communication dans un congrès hal-01606234v1
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Horizontal Gene Transfer is a key mechanism permitting adaptation of S. cerevisiae to its ecological niches

Virginie Galeote , Jean-Luc Legras , Frederic Bigey , Souhir Marsit , Carole Camarasa et al.

Reunión anual conjunta genética y evolución, 2017, Puerto Varas, Chile

Communication dans un congrès hal-01918076v1

Adaptive Advantage of Horizontally Transferred Oligopeptide Transporters in Wine Yeasts

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Virginie Galeote , Sylvie Dequin

27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), 2015, Trento, Italy

Communication dans un congrès hal-01606657v1

The genetic basis of adaptation of flor strains : a comparative genome and genetic analysis

Anna Lisa Coi , Jean-Luc Legras , Giacomo Zara , Frederic Bigey , Virginie Galeote et al.

32. International Specialised Symposium on Yeasts-Yeast biodiversity and biotechnology in the twenty-first century, 2015, Perugia, Italy

Communication dans un congrès hal-01606109v1

New insights into the adaptation of yeast to anthropic environment using comparative genomics

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

27. International Conference on Yeast Genetics and Molecular Biology (ICYGMB), Sep 2015, Trentino, Italy. pp.1

Communication dans un congrès hal-01837824v1

New insights into adaptation of yeast to anthropic environment using comparative genomics

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

32. International Specialized Symposium on Yeasts-Yeast Biodiversity and biotechnology in the twenty-first century, 2015, Perugia, Italy

Communication dans un congrès hal-01606118v1

Improvement of wine yeast strains using adaptive evolution

Axelle Cadière , Valentin Tilloy , Carole Camarasa , Frederic Bigey , Stephane Guezenec et al.

ISSY 32, Sep 2015, Perugia, Italy

Communication dans un congrès hal-01606246v1

Deciphering the adaptation of yeast to anthropic environment using comparative genomics

Jean-Luc Legras , Anna Lisa Coi , Virginie Galeote , Frederic Bigey , Souhir Marsit et al.

ESF-EMBO Symposium, Exploring the genomic complexity and diversity of eukaryotes, 2015, Sant Feliu de Guixols, Spain

Communication dans un congrès hal-01606115v1

Exploring the adaptation of yeast to wine making environment using comparative genomics

Jean-Luc Legras , Frederic Bigey , Virginie Galeote , Souhir Marsit , Arnaud Couloux et al.

SMBE Satellite meeting SMBEBA 2015 "Investigating biological adaptation with NGS: data and models", May 2015, Montpellier, France

Communication dans un congrès hal-01837827v1

Adaptive Advantage Conferred by an Eukaryote-to-Eukaryote Gene Transfer Event in Wine Yeasts

Souhir Marsit , Adriana Mena , Frederic Bigey , Francois Xavier Sauvage , Arnaud Couloux et al.

ESF-EMBO Symposium, Exploring the genomic complexity and diversity of eukaryotes, 2015, Sant Feliu de Guixols, Spain

Communication dans un congrès hal-01606164v1

New insights into the adaptation of yeast to anthropic niches using comparative genomics. Focus on flor yeast.

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

EMBO Conference Series: Experimental Approaches to Evolution and Ecology, Oct 2014, Heidelberg, Germany. pp.1

Communication dans un congrès hal-01837724v1

Adaptation des levures S. cerevisiae à des niches anthropiques à partir d’une approche de génomique des populations. Exemple de l’élevage en voile

Jean-Luc Legras , Anna Lisa Coi , Virginie Galeote , Frederic Bigey , Souhir Marsit et al.

Levures, Modèles & Outils – 11ème Rencontre des Levuristes Francophones, 2014, Bordeaux, France

Communication dans un congrès hal-01606112v1

Avantage adaptatif des transporteurs d’oligopeptides Fot1/2 acquis par transfert horizontal de gènes durant la fermentation alcoolique

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Sylvie Dequin , Virginie Galeote

Levures, Modèles & Outils – 11ème Rencontre des Levuristes Francophones, 2014, Bordeaux, France

Communication dans un congrès hal-01606218v1
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Evolutionnary and reverse engineering of commercially important metabolic traits in wine yeast

Axelle Cadière , Valentin Tilloy , Carole Camarasa , Frederic Bigey , Stephane Guezenec et al.

31. International Specialised Symposium on Yeast, 2014, Nova Gorica/Vipava, Slovenia

Communication dans un congrès hal-01605611v1

Characterization of genes involved in the adaptation of flor strains to biological ageing conditions of sherry wines

Anna Lisa Coi , Jean-Luc Legras , Frederic Bigey , Virginie Galeote , Ilaria Mannazzu et al.

31. International Specialised Symposium on Yeast, 2014, Nova-Gorica/Vipava, Slovenia

Communication dans un congrès hal-01606116v1

Adaptive role of horizontal gene transfers in wine yeasts: how to improve resource utilization to survive better

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Virginie Galeote , Sylvie Dequin

International Union of Microbiological Societies Congresses - IUMS2014, 2014, Montreal, Canada

Communication dans un congrès hal-01603322v1

Adaptive role of horizontally transferred oligopeptide transporters in wine yeasts

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Virginie Galeote , Sylvie Dequin

31. International Specialised Symposium on Yeast, 2014, Nova-Gorica/Vipava, Slovenia

Communication dans un congrès hal-01604147v1

New insights into the adaptation of yeast to anthropic niches using comparative genomics. Focus on flor yeast genome

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

ESF-EMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain

Communication dans un congrès hal-01606114v1

Role of horizontally transfered genes in the adaptation of wine yeasts to their environnment

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Sylvie Dequin , Virginie Galeote

5. Conference on Physiology of Yeast and Filamentous Fungi- PYFF5, 2013, Montpellier, France

Communication dans un congrès hal-01607571v1

Adaptive role of horizontally transferred genes during wine fermentation.

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Sylvie Dequin , Virginie Galeote

ESF-EMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain

Communication dans un congrès hal-01603320v1

First insight into the adaptation of yeast to anthropic niches from genome sequence

Jean-Luc Legras , Virginie Galeote , Frederic Bigey , Anna Lisa Coi , Souhir Marsit et al.

5. Conference on Physiology of Yeast and Filamentous Fungi, Institut National de Recherche Agronomique (INRA). UMR Sciences Pour l'Oenologie (1083)., 2013, Montpellier, France

Communication dans un congrès hal-01606119v1

Characterization of genes involved in yeast adaptation to Sherry-like wines’ biological ageing identified by a genome based approach

Anna Lisa Coi , Jean-Luc Legras , Frederic Bigey , Virginie Galeote , Marilena Budroni et al.

ESFEMBO Comparative Genomics of Eukaryotic Microorganisms: Complexity Patterns in Eukaryotic Genomes, 2013, Sant Feliu de Guixols, Spain

Communication dans un congrès hal-01606650v1
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Diversity and adaptation of flor yeast : new data for an old question

Jean-Luc Legras , Frederic Bigey , Anna Lisa Coi , Virginie Galeote , Claudine Charpentier et al.

Journées des Microbiologistes de l’INRA 2012, Nov 2012, Avignon, France

Communication dans un congrès hal-02804040v1

Diversity and adaptation of flor yeast : new data for an old question

Jean-Luc Legras , Frederic Bigey , Anna Lisa Coi , Virginie Galeote , Claudine Charpentier et al.

13. International Congress on Yeasts (ICY 2012), 2012, Madison, United States

Communication dans un congrès hal-02808760v1

Genetic and phenotypic diversity of wine yeasts: Role of horizontal gene transfer

Virginie Galeote , Frederic Bigey , Jean-Luc Legras , Souhir Marsit , Sylvie Dequin

13. International Congress on Yeasts (ICY 2012), Aug 2012, Madison, United States

Communication dans un congrès hal-02805677v1

Transformation of whole cells of Brevibacterium SP. R312, a nitrile hydratase producing strain

C.N.K. Chan Kwo Chion , Frederic Bigey , A. Arnaud , P. Galzy

6. Forum for applied biotechnology, Sep 1992, Bruges, Belgium

Communication dans un congrès hal-02843227v1
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Candida anglica, a yeast species newly found in cheese

Frédéric Bigey , Xavière Menatong Tene , Marc Wessner , Martine Pradal , Jean-Marc Aury et al.

WDS 2024, Oct 2024, Paris, France

Poster de conférence hal-05288556v1

Yeast dispersion is the main driver of microbial community diversity in sourdough bread-making

Lauriane Mietton , Jennifer Mata-Orozco , Hugo Devillers , Théo Guillerminet , Stéphane Guezenec et al.

PYYF8 - 8. Conference on Physiology of Yeasts and Filamentous Fungi, Jun 2023, Cork, Ireland

Poster de conférence hal-04237767v1

Genome and gene copy number variation in bakery yeast domestication

Frédéric Bigey , Diego Segond , Anne Friedrich , Stephane Guezenec , Aurélie Bourgais et al.

EMBL Conference: Molecular Mechanisms in Evolution and Ecology, Sep 2020, Online, Germany

Poster de conférence hal-02952117v1
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Multiple genetic origins of Saccharomyces cerevisiae in bakery

Frédéric Bigey , Diego Segond , Lucie Huyghe , Nicolas Agier , Aurélie Bourgais et al.

Comparative genomics of eukaryotic microbes: genomes in flux, and flux between genomes, Oct 2019, Sant Feliu de Guixols, Spain

Poster de conférence hal-02950887v1
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New insights into the adaptation of yeast to wine making using comparative genomics

Jean-Luc Legras , Anna Lisa Coi , Frederic Bigey , Virginie Galeote , Souhir Marsit et al.

10. Symposium International d’Œnologie de Bordeaux, Œno2015, Jun 2015, Bordeaux, France. 2015

Poster de conférence hal-01606120v1
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Adaptive advantage of oligopetide transporters acquired by horizontal transfer during wine fermentation

Souhir Marsit , Frederic Bigey , Jean-Luc Legras , Sylvie Dequin , Virginie Galeote

10. Symposium International d’Œnologie de Bordeaux, Œno2015, Jun 2015, Bordeaux, France. 2015

Poster de conférence hal-01603326v1

Enhanced production of volatile esters by adaptively evolved Saccharomyces cerevisiae wine yeasts

Sylvie Dequin , Axelle Cadière , Bastien Serrano , Carole Camarasa , Frederic Bigey

26. International Conference on Yeast Genetics and Molecular Biology, Aug 2013, Francfort-sur-le-Main, Germany. Wiley-Blackwell, Yeast, 30 (suppl.1), 2013, Yeast

Poster de conférence hal-01837753v1
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Stochastic gene expression, phenotypic variability and adaptation of budding yeast to environmental stresses

Hélène Martin-Yken , Marlène Vuillemin , Frédéric Bigey , Sylvie Dequin , Jean-Marie François et al.

EMBO conference: Comparative Genomics Of Eukaryotic Microorganisms: Understanding The Complexity Of Diversity, Oct 2011, Sant Feliu de Guixols, Spain

Poster de conférence hal-02952066v1

Relief From Nitrogen Starvation Triggers A Transient Destabilization Of Glycolytic Mrnas In Saccharomyces Cerevisiae Cells

Frédéric Bigey , Catherine Tesnière , Bruno Blondin , Martine Pradal , Isabelle Sanchez et al.

Dataset 10.5281/zenodo.571107

Relief from nitrogen starvation triggers a transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells

Frédéric Bigey , Catherine Tesnière , Bruno Blondin , Martine Pradal , Isabelle Sanchez et al.

Dataset 10.5281/zenodo.604787

Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes

Frédéric Bigey , Delphine Sicard

Dataset 10.5281/zenodo.3862175

Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes

Frédéric Bigey , Delphine Sicard

Dataset 10.5281/zenodo.3759218

Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae

Frédéric Bigey , Catherine Tesnière

Dataset 10.5281/zenodo.1295508

Relief from nitrogen starvation triggers a transient destabilization of glycolytic mRNAs in Saccharomyces cerevisiae cells

Frédéric Bigey , Catherine Tesnière , Bruno Blondin , Martine Pradal , Isabelle Sanchez et al.

Dataset 10.5281/zenodo.1064061

Relief from nitrogen starvation entails quick unexpected down-regulation of glycolytic/lipid metabolism genes in enological Saccharomyces cerevisiae

Frédéric Bigey , Catherine Tesnière

Dataset 10.5281/zenodo.1295507

Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes

Frédéric Bigey , Delphine Sicard

Dataset 10.5281/zenodo.4017165

Evidence for two main domestication trajectories in Saccharomyces cerevisiae linked to distinct bread-making processes

Frédéric Bigey

Dataset 10.5281/zenodo.3759219