Gérard LIZARD

Chercheur Associé au laboratoire Interdisciplinaire Carnot de Bourgogne (ICB), Université Bourgogne Europe (Dijon, France)
55 %
Libre accès
133
Documents
Affiliation actuelle
  • Laboratoire Interdisciplinaire Carnot de Bourgogne (ICB)
Identifiants chercheurs
Contact

Présentation

My primary expertise concerns lipotoxicity of oxysterols as well as lipid metabolism (peroxisome, mitochondria) in the field of aging and age-related diseases (ARD). I have an excellent expertise on oxidative stress, inflammation, and cell death and on the identification of natural and synthetic molecules (polyphenols, phytosterols, aza-stilbenes, fatty acids) and oils in the context of therapeutic strategies focused on ARD. I have a clinical expertise on ARD for the identification of biomarkers, and an important expertise in nanotoxicology. Technically, I am an expert in flow cytometry and image analysis.

Domaines de recherche

Biochimie, Biologie Moléculaire Biologie cellulaire

Compétences

Lipids, oxidative stress, inflammation, cell death, nanotoxicology

Publications

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Publications

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7-ketocholesterol as a theranostic target: Potential applications and future perspectives

Gérard Lizard , Khouloud Sassi , John J Mackrill , Imen Ghzaiel , Smail Meziane et al.

Chemistry and Physics of Lipids, 2026, 276-277, pp.105588. ⟨10.1016/j.chemphyslip.2026.105588⟩

Article dans une revue (article de synthèse) hal-05590394v1
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Preparation of hybrid SPIONs and nanodiamonds in view of neurodegenerative diseases treatments

Nimisha Singh , Thomas Nury , Leya Liu , Julien Boudon , Lionel Maurizi et al.

Colloids and Surfaces B: Biointerfaces, 2026, 257, pp.115170. ⟨10.1016/j.colsurfb.2025.115170⟩

Article dans une revue hal-05296064v1
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Oxysterols, age-related-diseases and nutritherapy: Focus on 7-ketocholesterol and 7β-hydroxycholesterol

Anne Vejux , Imen Ghzaiel , John J. Mackrill , Irundika H. K. Dias , Leila Rezig et al.

Prostaglandins and Other Lipid Mediators, 2025, 178, pp.106993. ⟨10.1016/j.prostaglandins.2025.106993⟩

Article dans une revue hal-05097486v1

Synthesis and structural characterization of coumarin–hydrazone derivatives as antiplatelet agents: in vitro and in silico evaluation of activity and toxicity

Asma Haffouz , Emna Khdhiri , Ines Dhouib , Ikram Ben Amor , Amira Jerbi et al.

3 Biotech, 2025, 15 (9), pp.322. ⟨10.1007/s13205-025-04495-z⟩

Article dans une revue hal-05490851v1

Analytical subcellular fractionation of microglial BV-2 cells with peroxisomal beta-oxidation defect

Mounia Tahri-Joutey , Isabelle Hamer , Virginie Tevel , Quentin Raas , Catherine Gondcaille et al.

Histochemistry and Cell Biology, 2025, 163 (1), pp.44. ⟨10.1007/s00418-025-02372-7⟩

Article dans une revue hal-05097597v1
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Influence of Mediterranean Diet and Incidence of Global Warming on Food Habits and Plant Growth in Northern Mediterranean Latitudes: Narrative Review

Norbert Latruffe , Gérard Lizard

Nutrients, 2025, 17 (4), pp.677. ⟨10.3390/nu17040677⟩

Article dans une revue (article de synthèse) hal-04994065v1
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Arginase Activity Inhibition With Thymoquinone Induces a Hybrid Type of Cell‐Death in MDA‐MB‐231 Cell Line

Jaweher Bday , Moufida Souid , Vivien Pires , Sallouha Gabbouj , Anne Véjux et al.

Journal of Biochemical and Molecular Toxicology, 2025, 39 (2), pp.e70130. ⟨10.1002/jbt.70130⟩

Article dans une revue hal-04971106v1
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Oxysterol-Induced Inflammation in Human Diseases: Strategies for Treatment with Natural Compounds and Synthetic Molecules

Fatiha Brahmi , John J. Mackrill , Imen Ghzaiel , Leila Rezig , Rym Benkhalifa et al.

Molecules, 2025, 30 (13), pp.2883. ⟨10.3390/molecules30132883⟩

Article dans une revue (article de synthèse) hal-05187131v1
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Anthocyanins - dietary natural products with a variety of bioactivities for the promotion of human and animal health

Andy Wai Kan Yeung , Magdalena Solka , Artur Jóźwik , Natalia Ksepka , Maima Matin et al.

Animal Science Papers and Reports, 2024, 42 (1), pp.5 - 34. ⟨10.2478/aspr-2023-0020⟩

Article dans une revue hal-04666248v1
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Current advances in phytosterol free forms and esters: Classification, biosynthesis, chemistry, and detection

Farid Khallouki , Wafa Zennouhi , Lhoussain Hajji , Mohamed Bourhia , Laila Benbacer et al.

Steroids, 2024, 212, pp.109520. ⟨10.1016/j.steroids.2024.109520⟩

Article dans une revue inserm-04772028v2
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Exploring the Role of Apigenin in Neuroinflammation: Insights and Implications

Karine Charrière , Vincent Schneider , Manon Perrignon-Sommet , Gérard Lizard , Alexandre Benani et al.

International Journal of Molecular Sciences, 2024, 25 (9), pp.5041. ⟨10.3390/ijms25095041⟩

Article dans une revue (article de synthèse) hal-04666378v1
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Lipid droplets dependent or independent cytoprotective activities of unsaturated fatty acids, Lorenzo’s oil and sulfo-N-succinimidyl oleate on 7-ketocholesterol-induced oxidative stress, organelle dysfunction and cell death on 158N and ARPE-19 cells: Cell targets and benefits of sulfo-N-succinimidyl oleate

Thomas Nury , Imen Ghzaiel , Aziz Hichami , Claudio Caccia , Valerio Leoni et al.

Current Research in Biotechnology, 2024, 7, pp.100195. ⟨10.1016/j.crbiot.2024.100195⟩

Article dans une revue hal-04664953v2
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Cytoprotective effects of α-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid, oleic acid and α-tocopherol on 7-ketocholesterol – Induced oxiapoptophagy: Major roles of PI3-K / PDK-1 / Akt signaling pathway and glutathione peroxidase activity in cell rescue

Aline Yammine , Imen Ghzaiel , Vivien Pires , Amira Zarrouk , Omar Kharoubi et al.

Current Research in Toxicology, 2024, 6, pp.100153. ⟨10.1016/j.crtox.2024.100153⟩

Article dans une revue hal-04665371v1
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Octadecaneuropeptide, ODN, Promotes Cell Survival against 6-OHDA-Induced Oxidative Stress and Apoptosis by Modulating the Expression of miR-34b, miR-29a, and miR-21in Cultured Astrocytes

Amine Bourzam , Yosra Hamdi , Seyma Bahdoudi , Karthi Duraisamy , Mouna El Mehdi et al.

Cells, 2024, 13 (14), pp.1188. ⟨10.3390/cells13141188⟩

Article dans une revue hal-04669034v1
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Characterization of <i>Silybum marianum</i> and <i>Silybum eburneum</i> seed oils: Phytochemical profiles and antioxidant properties supporting important nutritional interests

Samah Maaloul , Imen Ghzaiel , Maher Mahmoudi , Hédi Mighri , Vivien Pires et al.

PLoS ONE, 2024, 19 (6), pp.e0304021. ⟨10.1371/journal.pone.0304021⟩

Article dans une revue hal-04666055v1
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European Network for oxysterol research (ENOR): 10th ENOR symposium – Web meeting

Gérard Lizard , Marc Poirot , Luigi Iuliano

Steroids, 2023, 195, pp.109242. ⟨10.1016/j.steroids.2023.109242⟩

Article dans une revue inserm-04165320v1
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Two Argan Oil Phytosterols, Schottenol and Spinasterol, Attenuate Oxidative Stress and Restore LPS-Dysregulated Peroxisomal Functions in <i>Acox1<sup>−/−</sup></i> and Wild-Type BV-2 Microglial Cells

Soukaina Essadek , Catherine Gondcaille , Stéphane Savary , Mohammad Samadi , Joseph Vamecq et al.

Antioxidants , 2023, 12 (1), pp.168. ⟨10.3390/antiox12010168⟩

Article dans une revue hal-03994321v1
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Celebrating the 10th anniversary of the creation of the European Network for Oxysterol Research (ENOR)

Gérard Lizard , Marc Poirot , Luigi Iuliano

Journal of Steroid Biochemistry and Molecular Biology, 2022, pp.106114. ⟨10.1016/j.jsbmb.2022.106114⟩

Article dans une revue inserm-03649224v1
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The International Natural Product Sciences Taskforce (INPST) and the power of Twitter networking exemplified through #INPST hashtag analysis

Rajeev K. Singla , Ronita De , Thomas Efferth , Bruno Mezzetti , M. D. Sahab Uddin et al.

Phytomedicine, 2022, 108, pp.154520. ⟨10.1016/j.phymed.2022.154520⟩

Article dans une revue hal-03994795v1
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Profiles of Fatty Acids, Polyphenols, Sterols, and Tocopherols and Scavenging Property of Mediterranean Oils: New Sources of Dietary Nutrients for the Prevention of Age-related Diseases

Leila Rezig , Lucy Martine , Thomas Nury , Kamel Msaada , Nesrine Mahfoudhi et al.

Journal of oleo science, 2022, 71 (8), pp.1117-1133. ⟨10.5650/jos.ess22110⟩

Article dans une revue hal-03749395v1

Cytoprotective activities of representative nutrients from the Mediterranean diet and of Mediterranean oils against 7-ketocholesterol- and 7β-hydroxycholesterol-induced cytotoxicity: Application to age-related diseases and civilization diseases

Leila Rezig , Imen Ghzaiel , Mohamed Ksila , Aline Yammine , Thomas Nury et al.

Steroids, 2022, 187, pp.109093. ⟨10.1016/j.steroids.2022.109093⟩

Article dans une revue hal-04842281v1
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Protective effects of milk thistle (Sylibum marianum) seed oil and α-tocopherol against 7β-hydroxycholesterol-induced peroxisomal alterations in murine C2C12 myoblasts: Nutritional insights associated with the concept of pexotherapy

Imen Ghzaiel , Amira Zarrouk , Soukaina Essadek , Lucy Martine , Souha Hammouda et al.

Steroids, 2022, 183, pp.109032. ⟨10.1016/j.steroids.2022.109032⟩

Article dans une revue hal-03715700v1
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Sources of 7-ketocholesterol, metabolism and inactivation strategies: food and biomedical applications

Imen Ghzaiel , Khouloud Sassi , Amira Zarrouk , Shubhrima Ghosh , Irundika Dias et al.

Redox Experimental Medicine, 2022, 2022 (1), pp.R40-R56. ⟨10.1530/REM-22-0005⟩

Article dans une revue hal-04506089v1
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Protective Effect of Nopal Cactus (Opuntia ficus-indica) Seed Oil against Short-Term Lipopolysaccharides-Induced Inflammation and Peroxisomal Functions Dysregulation in Mouse Brain and Liver

Mounia Tahri-Joutey , Fatima-Ezzahra Saih , Riad El Kebbaj , Catherine Gondcaille , Joseph Vamecq et al.

International Journal of Molecular Sciences, 2022, 23 (19), pp.11849. ⟨10.3390/ijms231911849⟩

Article dans une revue hal-04342093v1
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European network for oxysterol research (ENOR): 10 th anniversary

Gérard Lizard , Marc Poirot , Luigi Iuliano

Journal of Steroid Biochemistry and Molecular Biology, 2021, 214, pp.105996. ⟨10.1016/j.jsbmb.2021.105996⟩

Article dans une revue inserm-03394448v1
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Attenuation of 7-ketocholesterol- and 7β-hydroxycholesterol-induced oxiapoptophagy by nutrients, synthetic molecules and oils: Potential for the prevention of age-related diseases

T. Nury , A. Yammine , I. Ghzaiel , K. Sassi , A. Zarrouk et al.

Ageing Research Reviews - ARR, 2021, 68, pp.101324. ⟨10.1016/j.arr.2021.101324⟩

Article dans une revue hal-04506059v1
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Antioxidant properties and cytoprotective effect of pistacia lentiscus l. Seed oil against 7β-hydroxycholesterol-induced toxicity in c2c12 myoblasts: Reduction in oxidative stress, mitochondrial and peroxisomal dysfunctions and attenuation of cell death

Imen Ghzaiel , Amira Zarrouk , Thomas Nury , Michela Libergoli , Francesca Florio et al.

Antioxidants , 2021, 10 (11), pp.1772. ⟨10.3390/antiox10111772⟩

Article dans une revue hal-03443580v1
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7-Ketocholesterol: Effects on viral infections and hypothetical contribution in COVID-19

Imen Ghzaiel , Khouloud Sassi , Amira Zarrouk , Thomas Nury , Mohamed Ksila et al.

Journal of Steroid Biochemistry and Molecular Biology, 2021, 212, pp.105939. ⟨10.1016/j.jsbmb.2021.105939⟩

Article dans une revue hal-04842319v1
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7-ketocholesterol and 7β-hydroxycholesterol: in vitro and animal models used to characterize their activities and to identify molecules preventing their toxicity

Anne Vejux , Dehbia Abed-Vieillard , Khadija Hajji , Amira Zarrouk , John Mackrill et al.

Biochemical Pharmacology, 2020, 173, pp.113648. ⟨10.1016/j.bcp.2019.113648⟩

Article dans une revue (article de synthèse) hal-02308654v1
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Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases

Olfa Masmoudi-Kouki , Amira Namsi , Yosra Hamdi , Seyma Bahdoudi , Ikram Ghouili et al.

Frontiers in Endocrinology, 2020, 11, pp.566026. ⟨10.3389/fendo.2020.566026⟩

Article dans une revue (article de synthèse) hal-05156163v1

7-Ketocholesterol- and 7β-Hydroxycholesterol-Induced Peroxisomal Disorders in Glial, Microglial and Neuronal Cells: Potential Role in Neurodegeneration

Thomas Nury , Aline Yammine , Franck Menetrier , Amira Zarrouk , Anne Vejux et al.

Advances in Experimental Medicine and Biology, 2020, Advances in Experimental Medicine and Biology, 1299, pp.31-41. ⟨10.1007/978-3-030-60204-8_3⟩

Article dans une revue hal-04759823v1
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Taurine-Conjugated Mussel-Inspired Iron Oxide Nanoparticles with an Elongated Shape for Effective Delivery of Doxorubicin into the Tumor Cells

Nimisha Singh , Nadine Millot , Lionel Maurizi , Gérard Lizard , Rajender Kumar

ACS Omega, 2020, 5 (26), pp.16165-16175. ⟨10.1021/acsomega.0c01747⟩

Article dans une revue hal-02902885v1
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Oxysterols and sterols: from lipidomics to food sciences

M Rodriguez-Estrada , V Cardenia , Marc Poirot , L Iuliano , G. Lizard

Journal of Steroid Biochemistry and Molecular Biology, 2019, 196, pp.105515. ⟨10.1016/j.jsbmb.2019.105515⟩

Article dans une revue inserm-02380514v1
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Elaboration of Trans-Resveratrol Derivative-Loaded Superparamagnetic Iron Oxide Nanoparticles for Glioma Treatment

Fadoua Sallem , Rihab Haji , Dominique Vervandier-Fasseur , Thomas Nury , Lionel Maurizi et al.

Nanomaterials, 2019, 9 (2), pp.287. ⟨10.3390/nano9020287⟩

Article dans une revue hal-02163534v1
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Dimethyl fumarate and monomethyl fumarate attenuate oxidative stress and mitochondrial alterations leading to oxiapoptophagy in 158N murine oligodendrocytes treated with 7β-hydroxycholesterol

Randa Sghaier , Thomas Nury , Valerio Leoni , Claudio Caccia , Jean-Paul Pais de Barros et al.

Journal of Steroid Biochemistry and Molecular Biology, 2019, 194, pp.105432. ⟨10.1016/j.jsbmb.2019.105432⟩

Article dans une revue hal-03487954v1

A microglial cell model for acyl-CoA oxidase 1 deficiency

Q. Raas , F-E Saih , C. Gondcaille , D. Trompier , Y. Hamon et al.

Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (4), pp.567-576. ⟨10.1016/j.bbalip.2018.10.005⟩

Article dans une revue hal-02359450v1

Profile of fatty acids, tocopherols, phytosterols and polyphenols in mediterranean oils (argan oils, olive oils, milk thistle seed oils and nigella seed oil) and evaluation of their antioxidant and cytoprotective activities

Amira Zarrouk , Lucy Martine , Stéphane Grégoire , Thomas Nury , Wiem Meddeb et al.

Current Pharmaceutical Design, 2019, 25 (15), pp.1791-1805. ⟨10.2174/1381612825666190705192902⟩

Article dans une revue (article de synthèse) istex hal-02622321v1
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Induction of a non-apoptotic mode of cell death associated with autophagic characteristics with steroidal maleic anhydrides and 7β-hydroxycholesterol on glioma cells

K. Sassi , T. Nury , A. Zarrouk , R. Sghaier , A. Khalafi-Nezhad et al.

Journal of Steroid Biochemistry and Molecular Biology, 2019, 191, pp.105371. ⟨10.1016/j.jsbmb.2019.04.020⟩

Article dans une revue hal-03485843v1
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Flavonoids differentially modulate liver X receptors activity—Structure-function relationship analysis

Allan Fouache , Nada Zabaiou , Cyrille de Joussineau , Laurent Morel , Sandrine Silvente-Poirot et al.

Journal of Steroid Biochemistry and Molecular Biology, 2019, 190, pp.173-182. ⟨10.1016/j.jsbmb.2019.03.028⟩

Article dans une revue inserm-02380571v1
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Octadecaneuropeptide (ODN) Induces N2a Cells Differentiation through a PKA/PLC/PKC/MEK/ERK-Dependent Pathway: Incidence on Peroxisome, Mitochondria, and Lipid Profiles

Amira Namsi , Thomas Nury , Amira Khan , Jérôme Leprince , David Vaudry et al.

Molecules, 2019, 24 (18), pp.3310. ⟨10.3390/molecules24183310⟩

Article dans une revue hal-02292144v1
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Peroxisomes in Immune Response and Inflammation

Francesca Di Cara , Pierre Andreoletti , Doriane Trompier , Anne Vejux , Margret H Bülow et al.

International Journal of Molecular Sciences, 2019, 20 (16), ⟨10.3390/ijms20163877⟩

Article dans une revue (article de synthèse) hal-04346483v1
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Protective function of autophagy during VLCFA-induced cytotoxicity in a neurodegenerative cell model

Margaux Doria , Thomas Nury , Dominique Delmas , Thibault Moreau , Gérard Lizard et al.

Free Radical Biology and Medicine, 2019, 137, pp.46 - 58. ⟨10.1016/j.freeradbiomed.2019.04.016⟩

Article dans une revue hal-03484454v1

CRISPR/Cas9-mediated knockout of Abcd1 and Abcd2 genes in BV-2 cells: novel microglial models for X-linked Adrenoleukodystrophy

Q. Raas , C. Gondcaille , Y. Hamon , V. Leoni , C. Caccia et al.

Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2019, 1864 (5), pp.704-714. ⟨10.1016/j.bbalip.2019.02.006⟩

Article dans une revue hal-02359446v1

Correlation of trans fatty acids with the severity of coronary artery disease lesions

Samia Hadj Ahmed , Wafa Kharroubi , Nadia Kaoubaa , Amira Zarrouk , Fathi Batbout et al.

Lipids in Health and Disease, 2018, 17 (1), ⟨10.1186/s12944-018-0699-3⟩

Article dans une revue hal-01932790v1
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Cytoprotective activities of milk thistle seed oil used in traditional tunisian medicine on 7-ketocholesterol and 24s-hydroxycholesterol-induced toxicity on 158n murine oligodendrocytes

Wiem Meddeb , Leila Rezig , Amira Zarrouk , Thomas Nury , Anne Vejux et al.

Antioxidants , 2018, 7 (7), pp.95. ⟨10.3390/antiox7070095⟩

Article dans une revue hal-02621118v1

The effect of oxysterols on nerve impulses.

Maryem Bezine , Amira Namsi , Randa Sghaier , Rym Ben Khalifa , Haithem Hamdouni et al. Article dans une revue istex hal-01873841v1

Induction of peroxisomal changes in oligodendrocytes treated with 7-ketocholesterol: Attenuation by α-tocopherol

Thomas Nury , Randa Sghaier , Amira Zarrouk , Franck Menetrier , Tugba Uzun et al.

Biochimie, 2018, 153, pp.181-202. ⟨10.1016/j.biochi.2018.07.009⟩

Article dans une revue istex hal-02621805v1
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In vitro interaction and biocompatibility of titanate nanotubes with microglial cells

S. Sruthi , A. Loiseau , J. Boudon , F. Sallem , Lionel Maurizi et al.

Toxicology and Applied Pharmacology, 2018, 353, pp.74-86. ⟨10.1016/j.taap.2018.06.013⟩

Article dans une revue hal-02163529v1

Lipid Biomarkers in Alzheimer's Disease

Amira Zarrouk , Meryam Debbabi , Maryem Bezine , El Mostafa Karym , Asmaa Badreddine et al.

Current Alzheimer Research, 2018, 15 (4), pp.303-312. ⟨10.2174/1567205014666170505101426⟩

Article dans une revue pasteur-01964927v1
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Modulation of Kv3.1b potassium channel level and intracellular potassium concentration in 158N murine oligodendrocytes and BV-2 murine microglial cells treated with 7-ketocholesterol, 24S-hydroxycholesterol or tetracosanoic acid (C24:0)

Maryem Bezine , Sonia Maatoug , Rym Ben Khalifa , Meryam Debbabi , Amira Zarrouk et al.

Biochimie, 2018, 153, pp.56-69. ⟨10.1016/j.biochi.2018.02.008⟩

Article dans une revue hal-01876263v1
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Cellular interactions of functionalized superparamagnetic iron oxide nanoparticles on oligodendrocytes without detrimental side effects: Cell death induction, oxidative stress and inflammation

S. Sruthi , Lionel Maurizi , T. Nury , F. Sallem , J. Boudon et al.

Colloids and Surfaces B: Biointerfaces, 2018, 170, pp.454-462. ⟨10.1016/j.colsurfb.2018.06.041⟩

Article dans une revue hal-02163524v1

Flow Cytometric Analysis of the Expression Pattern of Peroxisomal Proteins, Abcd1, Abcd2, and Abcd3 in BV-2 Murine Microglial Cells.

Meryam Debbabi , Thomas Nury , Imen Helali , El Mostafa Karym , Flore Geillon et al.

Methods in Molecular Biology, 2017, 1595, pp.257-265. ⟨10.1007/978-1-4939-6937-1_25⟩

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Comparison of the effects of major fatty acids present in the Mediterranean diet (oleic acid, docosahexaenoic acid) and in hydrogenated oils (elaidic acid) on 7-ketocholesterol-induced oxiapoptophagy in microglial BV-2 cells

Meryam Debbabi , Amira Zarrouk , Maryem Bezine , Wiem Meddeb , Thomas Nury et al.

Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.151-170. ⟨10.1016/j.chemphyslip.2017.04.002⟩

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Argan Oil-Mediated Attenuation of Organelle Dysfunction, Oxidative Stress and Cell Death Induced by 7-Ketocholesterol in Murine Oligodendrocytes 158N

Asmaa Badreddine , Amira Zarrouk , El Mostafa Karym , Meryam Debbabi , Thomas Nury et al.

International Journal of Molecular Sciences, 2017, 18 (10), pp.2220. ⟨10.3390/ijms18102220⟩

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Evidence of biological activity of Mentha species extracts on apoptotic and autophagic targets on murine RAW264.7 and human U937 monocytic cells

Fatiha Brahmi , Samia Hadj-Ahmed , Amira Zarrouk , Maryem Bezine , Thomas Nury et al.

Pharmaceutical biology, 2017, 55 (1), pp.286-293. ⟨10.1080/13880209.2016.1235208⟩

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Evidence of K+ homeostasis disruption in cellular dysfunction triggered by 7-ketocholesterol, 24S-hydroxycholesterol, and tetracosanoic acid (C24:0) in 158N murine oligodendrocytes

Maryem Bezine , Meryam Debbabi , Thomas Nury , Rym Ben-Khalifa , Mohammad Samadi et al.

Chemistry and Physics of Lipids, 2017, 207 (Pt B), pp.135-150. ⟨10.1016/j.chemphyslip.2017.03.006⟩

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Protective Effect of Cactus Cladode Extracts on Peroxisomal Functions in Microglial BV-2 Cells Activated by Different Lipopolysaccharides

Fatima-Ezzahra Saih , Pierre Andreoletti , Stéphane Mandard , Norbert Latruffe , M'Hammed Saïd El Kebbaj et al.

Molecules, 2017, 22 (1), pp.E102. ⟨10.3390/molecules22010102⟩

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Oxysterols and phytosterols in human health

Gérard Lizard , Charbel Massaad , Luigi Iuliano

Chemistry and Physics of Lipids, 2017, Epub ahead of print. ⟨10.1016/j.chemphyslip.2017.08.005⟩

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Mitochondrial dysfunction, oxidative stress and apoptotic induction in microglial BV-2 cells treated with sodium arsenate.

Wafa Kharroubi , Samia Haj Ahmed , Thomas Nury , Pierre Andreoletti , Rachid Sakly et al.

Journal of Environmental Sciences, 2017, 51, pp.44-51. ⟨10.1016/j.jes.2016.08.028⟩

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Attenuation of 7-ketocholesterol-induced overproduction of reactive oxygen species, apoptosis, and autophagy by dimethyl fumarate on 158 N murine oligodendrocytes

Amira Zarrouk , Thomas Nury , El-Mostafa Karym , Anne Vejux , Randa Sghaier et al.

Journal of Steroid Biochemistry and Molecular Biology, 2017, 169, pp.29-38. ⟨10.1016/j.jsbmb.2016.02.024⟩

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Contribution of cholesterol and oxysterols to the pathophysiology of Parkinson's disease.

Margaux Doria , Lucie Maugest , Thibault Moreau , Gérard Lizard , Anne Vejux

Advances in Free Radical Biology & Medicine, 2016, 101, pp.393-400. ⟨10.1016/j.freeradbiomed.2016.10.008⟩

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Generation of oxysterols formed by free radicals and enzymes by electrochemical oxidation

Gérard Lizard

European Journal of Lipid Science and Technology, 2016, 118 (2), pp.135-136

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STUDY OF THE ANTIOXIDANT ACTIVITY OF THE EXTRACTS OF THE ACHENES OF Sylibum marianum L.

Fatima Zohra Bessam , Zoheir Mehdadi , Gérard Lizard , Riad Djellouli

The International journal of biochemistry, 2016, 3 (2), pp.63-72

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Evidence of hormesis on human neuronal SK-N-BE cells treated with sodium arsenate: impact at the mitochondrial level.

Wafa Kharroubi , Samia Haj Ahmed , Thomas Nury , Pierre Andreoletti , Zohra Haouas et al.

Environmental Science and Pollution Research, 2016, 23 (9), pp.8441-52. ⟨10.1007/s11356-016-6043-4⟩

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Microglial cells (BV-2) internalize titanium dioxide (TiO2) nanoparticles: toxicity and cellular responses

Naima Rihane , Thomas Nury , Imen M’rad , Lassaad El Mir , Mohsen Sakly et al.

Environmental Science and Pollution Research, 2016, 23 (10), pp.9690 - 9699. ⟨10.1007/s11356-016-6190-7⟩

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Protective Effects of α-Tocopherol, γ-Tocopherol and Oleic Acid, Three Compounds of Olive Oils, and No Effect of Trolox, on 7-Ketocholesterol-Induced Mitochondrial and Peroxisomal Dysfunction in Microglial BV-2 Cells.

Meryam Debbabi , Thomas Nury , Amira Zarrouk , Nadia Mekahli , Maryem Bezine et al.

International Journal of Molecular Sciences, 2016, 17 (12), pp.E1973. ⟨10.3390/ijms17121973⟩

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Argan oil prevents down-regulation induced by endotoxin on liver fatty acid oxidation and gluconeogenesis and on peroxisome proliferator-activated receptor gamma coactivator-1 alpha, (PGC-1alpha), peroxisome proliferator-activated receptor gamma (PPARgamma) and estrogen related receptor alpha (ERRalpha)

Riad El Kebbaj , Pierre Andreoletti , Hammam L El Hajj , Youssef El Kharrassi , Joseph Vamecq et al.

Biochimie Open, 2015, 1, pp.51-59. ⟨10.1016/j.biopen.2015.10.002⟩

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An expeditious synthesis of spinasterol and schottenol, two phytosterols present in argan oil and in cactus pear seed oil, and evaluation of their biological activities on cells of the central nervous system

Asmaa Badreddine , Karym El Mostafa , Amira Zarrouk , Thomas Nury , Youssef El Kharrassi et al.

Steroids, 2015, 99 (B, SI), pp.119-124. ⟨10.1016/j.steroids.2015.01.005⟩

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Effects of cholesterol oxides on cell death induction and calcium increase in human neuronal cells (SK-N-BE) and evaluation of the protective effects of docosahexaenoic acid (DHA; C22:6 n-3)

Amira Zarrouk , Thomas Nury , Mohammad Samadi , Yvonne O'Callaghan , Mohamed Hammami et al.

Steroids, 2015, 99 (B, SI), pp.238-247. ⟨10.1016/j.steroids.2015.01.018⟩

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Induction of oxiapoptophagy on 158N murine oligodendrocytes treated by 7-ketocholesterol-, 7 beta-hydroxycholesterol-, or 24(S)-hydroxycholesterol: Protective effects of alpha-tocopherol and docosahexaenoic acid (DHA; C22:6 n-3)

Thomas Nury , Amira Zarrouk , John J. Mackrill , Mohammad Samadi , Philippe Durand et al.

Steroids, 2015, 99 (B, SI), pp.194-203. ⟨10.1016/j.steroids.2015.02.003⟩

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LXR antagonists induce ABCD2 expression

Catherine Gondcaille , Emmanuelle C. Genin , Tatiana E. Lopez , Alexandre M.M. Dias , Flore Geillon et al.

Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2014, 1841 (2), pp.259-266. ⟨10.1016/j.bbalip.2013.11.003⟩

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The role of reactive oxygen species and subsequent DNA-damage response in the emergence of resistance towards resveratrol in colon cancer models

D J Colin , E Limagne , K Ragot , G Lizard , F Ghiringhelli et al.

Cell Death & Disease, 2014, 5 (11), ⟨10.1038/cddis.2014.486⟩

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Biological activities of Schottenol and Spinasterol, two natural phytosterols present in argan oil and in cactus pear seed oil, on murine miroglial BV2 cells

M'Hammed Saïd El Kebbaj , David Masson , Gérard Lizard , Boubker Nasser , Mustapha Cherkaoui-Malki et al.

Biochemical and Biophysical Research Communications, 2014, 446 (3, SI), pp.798-804. ⟨10.1016/j.bbrc.2014.02.074⟩

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Brain Peroxisomes

Doriane Trompier , A. Vejux , A. Zarrouk , Catherine Gondcaille , Flore Geillon et al.

Biochimie, 2013, 98, pp.102-110. ⟨10.1016/j.biochi.2013.09.009⟩

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Improved synthesis and in vitro evaluation of the cytotoxic profile of oxysterols oxidized at C4 (4 alpha- and 4 beta-hydroxycholesterol) and C7 (7-ketocholesterol, 7 alpha- and 7 beta-hydroxycholesterol) on cells of the central nervous system

Thomas Nury , Mohammad Samadi , Amira Zarrouk , Jean Marc Riedinger , Gérard Lizard

European Journal of Medicinal Chemistry, 2013, 70, pp.558-567. ⟨10.1016/j.ejmech.2013.09.028⟩

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Phase I study of OM-174, a lipid A analogue, with assessment of immunological response, in patients with refractory solid tumors.

Nicolas Isambert , Pierre Fumoleau , Catherine Paul , Christophe Ferrand , Sylvie Zanetta et al.

BMC Cancer, 2013, 13 (1), pp.172. ⟨10.1186/1471-2407-13-172⟩

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Peroxisomal ABC transporters and X-linked adrenoleukodystrophy

Flore Geillon , Doriane Trompier , Catherine Gondcaille , Gérard Lizard , Stéphane Savary

Médecine/Sciences, 2012, 28 (12), pp.1087-1094. ⟨10.1051/medsci/20122812019⟩

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Correlational selection on pro- and anti-inflammatory effectors.

Romain Guerreiro , Anne A. Besson , Jérôme Bellenger , Kévin Ragot , Gérard Lizard et al.

Evolution - International Journal of Organic Evolution, 2012, 66 (11), pp.3615-3623. ⟨10.1111/j.1558-5646.2012.01708.x⟩

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Incidence of Abcd1 level on the induction of cell death and organelle dysfunctions triggered by very long chain fatty acids and TNF-alpha on oligodendrocytes and astrocytes

Mauhamad Baarine , Kevin Ragot , Anne Athias , Thomas Nury , Zilal Kattan et al.

NeuroToxicology, 2012, 33 (2), pp.212-228. ⟨10.1016/j.neuro.2011.10.007⟩

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The inflammatory response in acyl-CoA oxidase 1 deficiency (pseudoneonatal adrenoleukodystrophy).

Hammam I. El Hajj , Aurore Vluggens , Pierre Andreoletti , Kevin Ragot , Stéphane Mandard et al.

Endocrinology, 2012, 153 (6), pp.2568-75. ⟨10.1210/en.2012-1137⟩

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Absence of oxysterol-like side effects in human monocytic cells treated with phytosterols and oxyphytosterols

Anne Vejux , Thomas Montange , Lucy Martine , Amira Zarrouk , Jean-Marc Riedinger et al.

Journal of Agricultural and Food Chemistry, 2012, 60 (16), pp.4060-4066. ⟨10.1021/jf300487r⟩

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Impact of 7-Ketocholesterol and Very Long Chain Fatty Acids on Oligodendrocyte Lipid Membrane Organization: Evaluation Via LAURDAN and FAMIS Spectral Image Analysis

Edmond Kahn , Mauhamad Baarine , Aurélien Dauphin , Kevin Ragot , Nicolas Tissot et al.

Cytometry Part A, 2011, 79A (4), pp.293 - 305. ⟨10.1002/cyto.a.21017⟩

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Effects of oxysterols on cell viability, inflammatory cytokines, VEGF, and reactive oxygen species production on human retinal cells: cytoprotective effects and prevention of VEGF secretion by resveratrol.

B. Dugas , Soeli Charbonnier , Mauhamad Baarine , Kevin Ragot , Dominique Delmas et al.

European Journal of Nutrition, 2010, 49 (7), pp.435-46. ⟨10.1007/s00394-010-0102-2⟩

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Effects of resveratrol analogs on cell cycle progression, cell cycle associated proteins and 5fluoro-uracil sensitivity in human derived colon cancer cells.

Didier Colin , Amandine Gimazane , Gérard Lizard , Jean-Claude Izard , Eric Solary et al.

International Journal of Cancer, 2009, 124 (12), pp.2780-8. ⟨10.1002/ijc.24264⟩

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Branched-chain fatty acids, increased in tears of blepharitis patients, are not toxic for conjunctival cells

Corinne Joffre , Maxime Souchier , Laurent Leclere , Bénédicte Buteau , Stéphane Grégoire et al.

British Journal of Ophthalmology, 2009, 93 (10), pp.1391-n/a. ⟨10.1136/bjo.2008.156356⟩

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Preanalytical guidelines for clinical proteomics investigation of biological fluids

Sylvain Lehmann , S. Roche , Y. Allory , A. Barthelaix , J.-L. Beaudeux et al.

Annales de Biologie Clinique, 2009, 67 (6), pp.629-639. ⟨10.1684/abc.2009.0374⟩

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Phospholipidosis and down-regulation of the PI3-K/PDK-1/Akt signalling pathway are vitamin E inhibitable events associated with 7-ketocholesterol-induced apoptosis

Anne Vejux , Stéphane Guyot , Thomas Montange , Jean-Marc Riedinger , Edmond Kahn et al.

The Journal of Nutritional Biochemistry, 2009, 20 (1), pp.45-61. ⟨10.1016/j.jnutbio.2007.12.001⟩

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Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes.

Mauhamad Baarine , Kevin Ragot , Emmanuelle C. Genin , Hammam El Hajj , Doriane Trompier et al.

Journal of Neurochemistry, 2009, 111 (1), pp.119-31. ⟨10.1111/j.1471-4159.2009.06311.x⟩

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7β-Hydroxycholesterol and 25-hydroxycholesterol-induced interleukin-8 secretion involves a calcium-dependent activation of c-fos via the ERK1/2 signaling pathway in THP-1 cells. Oxysterols-induced IL-8 secretion is calcium-dependent

Stéphanie Lemaire-Ewing , Arnaud Berthier , Marie Charlotte Royer , Emmanuelle Logette , Laurent Corcos et al.

Cell Biology and Toxicology, 2008, 25, pp.127 - 139. ⟨10.1007/s10565-008-9063-0⟩

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Inhibitory effects of trans-resveratrol analogs molecules on the proliferation and the cell cycle progression of human colon tumoral cells.

Anna-Kristina Marel , Gérard Lizard , Jean-Claude Izard , Norbert Latruffe , Dominique Delmas

Molecular Nutrition and Food Research, 2008, 52 (5), pp.538-48. ⟨10.1002/mnfr.200700185⟩

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Antiproliferative activities of resveratrol and related compounds in human hepatocyte derived HepG2 cells are associated with biochemical cell disturbance revealed by fluorescence analyses.

Didier Colin , Allan Lancon , Dominique Delmas , Gérard Lizard , Jessica Abrossinow et al.

Biochimie, 2008, 90 (11-12), pp.1674-84. ⟨10.1016/j.biochi.2008.06.006⟩

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Activation of a caspase-3-independent mode of cell death associated with lysosomal destabilization in cultured human retinal pigment epithelial cells (ARPE-19) exposed to 7beta-hydroxycholesterol

Laure Malvitte , Thomas Montange , Anne Vejux , Corinne Joffre , Alain M. Bron et al.

Current Eye Research, 2008, 33 (9), pp.769-781. ⟨10.1080/02713680802337397⟩

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Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs

Laure Malvitte , Thomas Montange , Anne Vejux , Christophe Baudouin , Alain M. Bron et al.

British Journal of Ophthalmology, 2007, 91 (1), pp.29-32. ⟨10.1136/bjo.2006.101485⟩

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Cytotoxic oxysterols induce caspase-independent myelin figure formation and caspase-dependent polar lipid accumulation.

Anne Vejux , Edmond Kahn , Franck Ménétrier , Thomas Montange , Jeannine Lherminier et al.

Histochemie / Histochemistry Histochimie, 2007, 127 (6), pp.609-24. ⟨10.1007/s00418-006-0268-0⟩

Article dans une revue istex inserm-00164342v1
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Resveratrol in human hepatoma HepG2 cells: metabolism and inducibility of detoxifying enzymes.

Allan Lançon , Nathalie Hanet , Brigitte Jannin , Dominique Delmas , Jean-Marie Heydel et al.

Drug Metabolism and Disposition, 2007, 35 (5), pp.699-703. ⟨10.1124/dmd.106.013664⟩

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Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells

Corinne Joffre , Laurent Leclere , Bénédicte Buteau , Lucy Martine , Stéphanie S. Cabaret et al.

Current Eye Research, 2007, 32 (3), pp.271-280. ⟨10.1080/02713680601187951⟩

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Effects of caspase inhibitors (z-VAD-fmk, z-VDVAD-fmk) on Nile Red fluorescence pattern in 7-ketocholesterol-treated cells: Investigation by flow cytometry and spectral imaging microscopy.

Anne Vejux , Gérard Lizard , Yves Tourneur , Jean-Marc Riedinger , Frédérique Frouin et al.

Cytometry Part A, 2007, 71A (8), pp.550-562. ⟨10.1002/cyto.a.20410⟩

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Analogies entre le processus athéromateux et dégénérescence maculaire liée à l'âge : roles présumés des oxystérols

Laure Malvitte , Thomas Montange , Corinne Joffre , Aline Vejux , Caroline Maïza et al.

Journal Français d'Ophtalmologie, 2006, 29 (5), pp.570-578. ⟨10.1016/S0181-5512(06)73815-3⟩

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Flow cytometry and spectral imaging multiphoton microscopy analysis of CD36 expression with quantum dots 605 of untreated and 7-ketocholesterol-treated human monocytic cells.

Edmond Kahn , Franck Ménétrier , Anne Vejux , Thomas Montange , Dominique Dumas et al.

Analytical and Quantitative Cytology and Histology, 2006, 28 (6), pp.316-30

Article dans une revue hal-00559053v1

7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation.

Anne Vejux , Edmond Kahn , Dominique Dumas , Ginette Bessède , Franck Ménétrier et al.

Cytometry Part A, 2005, 64 (2), pp.87-100. ⟨10.1002/cyto.a.20124⟩

Article dans une revue hal-00559063v1

Activation of caspase-3-dependent and -independent pathways during 7-ketocholesterol- and 7beta-hydroxycholesterol-induced cell death: a morphological and biochemical study.

Prunet Céline , Lemaire-Ewing Stéphanie , Ménétrier Franck , Néel Dominique , Gérard Lizard

Journal of Biochemical and Molecular Toxicology, 2005, 19 (5), pp.311-26. ⟨10.1002/jbt.20096⟩

Article dans une revue istex hal-04971160v1

FRET multiphoton spectral imaging microscopy of 7-ketocholesterol and Nile Red in U937 monocytic cells loaded with 7-ketocholesterol.

Edmond Kahn , Anne Vejux , Dominique Dumas , Thomas Montange , Frédérique Frouin et al.

Analytical and Quantitative Cytology and Histology, 2004, 26 (6), pp.304-13

Article dans une revue hal-00559065v1

Analysis of fluorescent MRI contrast agent behavior in the liver and thoracic aorta of mice.

Edmond Kahn , Gérard Lizard , Dominique Dumas , Frédérique Frouin , Frank Ménétrier et al.

Analytical and Quantitative Cytology and Histology, 2004, 26 (4), pp.233-8

Article dans une revue hal-00559067v1

Chronology of cellular alterations during 7-ketocholesterol-induced cell death on A7R5 rat smooth muscle cells: analysis by time lapse-video microscopy and conventional fluorescence microscopy.

Jean-Marie Zahm , Sonia Baconnais , Serge Monier , Noël Bonnet , Ginette Bessède et al.

Cytometry Part A, 2003, 52 (2), pp.57-69. ⟨10.1002/cyto.a.10027⟩

Article dans une revue inserm-00148786v1

Microbilles, nanobilles et cytométrie : applications à l’analyse et à la purification cellulaire et moléculaire

G Lizard , L Duvillard , N Wedemeyer , C Muller , F Ghiringhelli et al.

Pathologie Biologie, 2003, 51 (7), pp.418-427. ⟨10.1016/S0369-8114(03)00127-5⟩

Article dans une revue istex hal-04980086v1

Early mitochondrial dysfunction, superoxide anion production, and DNA degradation are associated with non-apoptotic death of human airway epithelial cells induced by Pseudomonas aeruginosa exotoxin A.

Maria-Cristina Plotkowski , Helvécio Cc Póvoa , Jean-Marie Zahm , Gérard Lizard , Geraldo Mb Pereira et al.

American Journal of Respiratory Cell and Molecular Biology, 2002, 26 (5), pp.617-26

Article dans une revue inserm-00154288v1
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Plasma phospholipid transfer protein prevents vascular endothelium dysfunction by delivering α-tocopherol to endothelial cells

Catherine M Desrumaux , Valérie Deckert , Anne Athias , David Masson , Gérard Lizard et al.

FASEB Journal, 1999, 13 (8), pp.883-892. ⟨10.1096/fasebj.13.8.883⟩

Article dans une revue hal-04207349v1

Characterization and comparison of the mode of cell death, apoptosis versus necrosis, induced by 7á-hydroxycholesterol and 7-ketocholesterol in the cells of the vascular wall

G. Lizard , Sylvette Monier , Catherine Cordelet , L. Gesquière , V. Deckert et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 1999, 19, pp.1190-1200

Article dans une revue hal-02688564v1

Inhibition by Cholesterol Oxides of NO Release From Human Vascular Endothelial Cells

Valérie Deckert , Annie Brunet , Frédérique Lantoine , Gérard Lizard , Elisabeth Millanvoye-Van Brussel et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 1998, 18 (7), pp.1054-1060. ⟨10.1161/01.atv.18.7.1054⟩

Article dans une revue hal-03936665v1

Induction of similar features of apoptosis in human and bovine vascular endothelial cells treated by 7-ketocholesterol

G. Lizard , M. Moisant , Catherine Cordelet , Sylvette Monier , Philippe Gambert et al.

Journal of Pathology, 1997, 183, pp.330-338

Article dans une revue hal-02688324v1

Apoptosis without decrease of cell DNA content

Jean-Pierre Rouault , Sylvie Fournel , Laurent Genestier , Gérard Lizard , Monique Flacher et al.

FEBS Letters, 1995, 367 (2), pp.188-192. ⟨10.1016/0014-5793(95)00532-E⟩

Article dans une revue hal-02998634v1
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Application of laser scanning image cytometry for human chromosome microdissection and DNA analysis

P. Métézeau , G. Tachdjian , H. Kiefer , L. Druart , V. Cacheux et al.

Journal de Physique IV Proceedings, 1994, 04 (C4), pp.C4-265-C4-268. ⟨10.1051/jp4:1994461⟩

Article dans une revue istex jpa-00252724v1

Human melanoma cell lines differ in their capacity to release ADP and aggregate platelets.

H. Boukerche , O. Berthier-Vergnes , F. Penin , E. Tabone , G. Lizard et al.

Br J Haematol, 1994, 87, pp.763-772

Article dans une revue hal-00313722v1
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Prospective methods for human papillomavirus detection by fluorescent in situ hybridization and laser excitation

G. Lizard , C. Souchier , Y. Chardonnet

Journal de Physique IV Proceedings, 1994, 04 (C4), pp.C4-257-C4-260. ⟨10.1051/jp4:1994459⟩

Article dans une revue istex jpa-00252722v1

Human melanoma cell lines differ in their capacity to release ADP and aggregate platelets.

H. Boukerche , O. Berthier-Vergnes , F. Penin , E. Tabone , G. Lizard et al.

British Journal of Haematology, 1994, 87 (4), pp.763-72. ⟨10.1111/j.1365-2141.1994.tb06736.x⟩

Article dans une revue hal-00189850v1

Prevention of Oxysterol-Induced Oxiapoptophagy with Mediterranean Oils: Nutritherapeutic Approach of Age-Related Diseases

Gérard Lizard , Imen Ghzaiel , Samah Maaloul , Raoudha Abdellaoui , Smail Meziane et al.

Valorization of the Mediterranean Vegetal Biodiversity: Nutritional, Therapeutic and Biotechnologic Aspects, Adil El Midaoui; Jamaleddine Hafid; Fouad Seghrouchni; Norbert Latruffe; Gérard Lizard, Apr 2024, Marrakech, Morocco. pp.CA3

Communication dans un congrès hal-04854988v1

7-Ketocholesterol effects on survival and growth in Drosophila melanogaster

Dehbia Abed-Vieillard , Serge Loquin , William J. Griffiths , Haithem Hamdoun , Anne Vejux et al.

10. European Network for Oxysterol Research (ENOR) symposium, Sep 2021, Virtual meeting, France

Communication dans un congrès hal-03448141v1

Assessment of the toxicity of cholesterol oxides on retinal pigment epithelial cultured cells

Laure Malvitte , Thomas Montange , Corinne Joffre , Aline Vejux , Alain M. Bron et al.

Association for Research in Vision and Ophthalmology Annual Congress, Apr 2006, Fort Lauderdale, United States

Communication dans un congrès hal-02754354v1

Neuroprotective Effects of the Neuropeptide ODN against Inflammatory, Oxidative Stress, and Neurodegenerative Disorders Induced by Obesity

Mouna Sallemi , Yosra Hamdi , Gérard Lizard , Jérôme Leprince , Olfa Masmoudi

7th International Congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia. 2024

Poster de conférence hal-05169250v1

Protective and Neurotrophic Effects of octaDecaNeuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases

Yosra Hamdi , Ikram Ghouili , S. Mashadani , Amine Bourzam , Amira Namsi et al.

7th International Congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia. 2024

Poster de conférence hal-05169249v1

Octadecaneuropeptide (ODN) Mediated miRNA Regulation: A Novel Scientific Approach to Protect against Cell Death and Neuroinflammation in a Cellular Model of Neurodegenerative Disease

Amine Bourzam , Yosra Hamdi , Seyma Bahdoudi , Karthi Duraisamy , Mouna El Mehdi et al.

7. international congress of Biochemistry and Microbiology Applied Technologies, Nov 2024, Hammamet, Tunisia

Poster de conférence hal-05169247v1

Cytoprotective and Neurotrophic Effects of Octadecaneuropeptide (ODN) in in Vitro and in Vivo Models of Neurodegenerative Diseases

Yosra Hamdi , Tasnim Chagrani , Sada Al-Mashhadani , Ikram Ghouili , Jérôme Leprince et al.

9th Conference of the Mediterranean Neuroscience Society, Oct 2023, Carthage, Tunisia

Poster de conférence hal-05168092v1

Toxicity of Branched-Chain Fatty Acids in Conjunctival Cell Line

Maxime Souchier , Corinne Joffre , Laurent Leclère , Bénédicte Buteau , Stéphane Grégoire et al.

ARVO Annual Meeting, May 2007, Fort Lauderdale, United States. Association for Research in Vision and Ophthalmology, Investigative Ophthalmology and Visual Science, 48, pp.e-Abstract 5305, 2007, ARVO Annual Meeting Abstract

Poster de conférence hal-02757603v1

Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention

Allan Lançon , Nathalie Hanet , Brigitte Jannin , Dominique Delmas , Jean-Marie Heydel et al.

European Partnership Meetings: Taste, Nutrition, Health, Jun 2007, Dijon, France

Poster de conférence hal-03838370v1

Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention

Allan Lançon , Nathalie Hanet , Brigitte Jannin , Dominique Delmas , Jean-Marie Heydel et al.

2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France

Poster de conférence hal-03838598v1

In Vitro Evaluation of the Effects of 7-Ketocholesterol and 7β-Hydroxycholesterol on the Peroxisomal Status: Prevention of Peroxisomal Damages and Concept of Pexotherapy

Imen Ghzaiel , Samah Maaloul , Mohamed Ksila , Amira Namsi , Aline Yammine et al.

Gérard Lizard. Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.437-452, 2024, Advances in Experimental Medicine and Biology (AEMB), 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_21⟩

Chapitre d'ouvrage hal-04759802v1

Therapeutic Applications of Oxysterols and Derivatives in Age-Related Diseases, Infectious and Inflammatory Diseases, and Cancers

Mohamed Ksila , Imen Ghzaiel , Khouloud Sassi , Amira Zarrouk , Valerio Leoni et al.

Gérard Lizard. Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.379-400, 2023, Advances in Experimental Medicine and Biology (AEMB), 978-3-031-43882-0, 978-3-031-43885-1, 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_19⟩

Chapitre d'ouvrage hal-04843308v1

Chemical and Biochemical Features of Spinasterol and Schottenol

Farid Khallouki , Mohamed Ksila , Imen Ghzaiel , Soukaina Essadek , Mounia Tahri Joutey et al.

Implication of Oxysterols and Phytosterols in Aging and Human Diseases, 1440, Springer International Publishing, pp.45-55, 2023, Advances in Experimental Medicine and Biology, 978-3-031-43883-7. ⟨10.1007/978-3-031-43883-7_3⟩

Chapitre d'ouvrage hal-04509752v1

7-ketocholesterol- and 7β-hydroxycholesterol-induced peroxisomal disorders in glial, microglial and neuronal cells: Potential role in neurodegeneration

Thomas Nury , Aline Yammine , Franck Menetrier , Amira Zarrouk , Anne Vejux et al.

Gérard Lizard. Peroxisome Biology: Experimental Models, Peroxisomal Disorders and Neurological Diseases, 1299, Springer International Publishing, 2020, Advances in Experimental Medicine and Biology (AEMB), 978-3-030-60203-1 (print). ⟨10.1007/978-3-030-60204-8_3⟩

Chapitre d'ouvrage hal-03158086v1
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Toxicological Risk Assessment of Emerging Nanomaterials: Cytotoxicity, Cellular Uptake, Effects on Biogenesis and Cell Organelle Activity, Acute Toxicity and Biodistribution of Oxide Nanoparticles

Lionel Maurizi , Anne-Laure Papa , Julien Boudon , Sruthi Sudhakaran , Benoist Pruvot et al.

Unraveling the Safety Profile of Nanoscale Particles and Materials-From Biomedical to Environmental Applications, InTech, 2018, ⟨10.5772/intechopen.71833⟩

Chapitre d'ouvrage hal-02163546v1