Guillaume Moissiard

PI of Epi2Trans team at LGDP in Perpignan
56 %
Libre accès
16
Documents
Affiliation actuelle
  • Laboratoire Génome et développement des plantes (LGDP)
Contact

Présentation

Our team studies epigenetic pathways and chromatin factors regulating gene expression and repressing transposable elements (TEs). We are also characterizing the function of TE genes that have been exapted – also known as coopted or domesticated – by the plants. These genes, called exapted TE (ETE) genes can be of different origins, forming distinct gene families such as the Plant Mobile Domain, the MUSTANG or the SLEEPER families. Finally, we are studying the impact of TEs on transcriptomic diversity in plants subjected to abiotic stresses such as heat to understand how TEs can contribute to plant adaptation in response to environmental stresses. Our research is done in Arabidopsis and tomato, two plant species displaying very different genome organizations. We combine Illumina short-read and Oxford Nanopore technologies (ONT) long-read sequencing to study differential gene expression, full length RNA diversity, structural variations and epigenetic modifications. We use biochemical approaches to study chromatin/protein interaction (ChIP-seq) and protein interaction (IP-MS, CLNIP-MS, Co-IP, FPLC…)

Domaines de recherche

Biologie moléculaire Génomique, Transcriptomique et Protéomique [q-bio.GN] Génétique des plantes

Publications

Publications

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Plant mobile domain protein–DNA motif modules counteract Polycomb silencing to stabilize gene expression

Thierry Pélissier , Lucas Jarry , Margaux Olivier , Gabin Dajoux , Marie-Noëlle Pouch-Pélissier et al.

Nature Plants, In press, Online ahead of print. ⟨10.1038/s41477-025-02127-1⟩

Article dans une revue hal-05343329v1
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Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing

Lucas Jarry , Julie Descombin , Melody Nicolau , Ange Dussutour , Nathalie Picault et al.

Life Science Alliance, 2023, 6 (4), pp.e202201539. ⟨10.26508/lsa.202201539⟩

Article dans une revue hal-04038933v1
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Editorial: Plant epigenetics and chromatin dynamics - EPIPLANT 2021-2022

Guillaume Moissiard , Marie Mirouze , Cristel Carles , Clémentine Vitte

Frontiers in Plant Science, 2023, 14, ⟨10.3389/fpls.2023.1260391⟩

Article dans une revue hal-04305976v1
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The Evolutionary Volte-Face of Transposable Elements: From Harmful Jumping Genes to Major Drivers of Genetic Innovation

Melody Nicolau , Nathalie Picault , Guillaume Moissiard

Cells, 2021, 10 (11), pp.2952. ⟨10.3390/cells10112952⟩

Article dans une revue (article de synthèse) hal-03426512v1
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The plant mobile domain proteins MAIN and MAIL1 interact with the phosphatase PP7L to regulate gene expression and silence transposable elements in Arabidopsis thaliana

Melody Nicolau , Nathalie Picault , Julie Descombin , Yasaman Jami-Alahmadi , Suhua Feng et al.

PLoS Genetics, 2020, 16 (4), pp.e1008324. ⟨10.1371/journal.pgen.1008324⟩

Article dans une revue hal-02561768v1

Involvement of a Jumonji‐C domain‐containing histone demethylase in DRM2‐mediated maintenance of DNA methylation

Angelique Deleris , Maxim Greenberg , Israel Ausin , Rona Law , Guillaume Moissiard et al.

EMBO Reports, 2010, 11 (12), pp.950-955. ⟨10.1038/embor.2010.158⟩

Article dans une revue hal-03439089v1

The Plant Mobile Domain proteins antagonize the Polycomb group protein- mediated gene silencing

Jarry Lucas , Pélissier Thierry , Olivier Margaux , Dajoux Gabin , Pouch-Pélissier M.N. et al.

Plant Epigenetics - Epiplant Meeting 2024, Jul 2024, Clermont-Ferrand, France

Communication dans un congrès hal-04890576v1

Transposable elements: between epigenetics and adaptive functions

Guillaume Moissiard

Plant Epigenetics Symposium at UCLA, Mar 2024, Los Angeles (CA), United States

Communication dans un congrès hal-04888989v1

Transposable elements: between epigenetic repression and adaptive function in plants.

Guillaume Moissiard

GDR Mobil-ET annual meeting, Dec 2023, Paris, France

Communication dans un congrès hal-04889591v1

Plant mobile domain proteins ensure Microrchidia 1 expression to fulfill transposon silencing

Lucas Jarry , Julie Descombin , Melody Nicolau , Ange Dussutour , Nathalie Picault et al.

CNET 2023 GDR Mobil-ET, Jul 2023, Perpignan, France. pp.e202201539, ⟨10.26508/lsa.202201539⟩

Communication dans un congrès hal-04889559v1

Role of Plant Mobile Domain proteins in the regulation of gene expression

Guillaume Moissiard

Abcam Chromatin and Epigenetics meeting: Inheritance and Design, Apr 2019, Munich, France

Communication dans un congrès hal-04889611v1