Guylaine Hoffner

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Documents
Affiliations actuelles
  • Neuroimagerie cognitive - Psychologie cognitive expérimentale (UNICOG-U992)
  • Service NEUROSPIN (NEUROSPIN)
Identifiants chercheurs
Contact

Domaines de recherche

Biochimie [q-bio.BM] Sciences cognitives Sciences du Vivant [q-bio] Biophysique Biologie cellulaire Imagerie Neurosciences [q-bio.NC] Neurobiologie

Compétences

Stimulation transcrânienne à courant continu Neuromodulation Conscience Imagerie par résonnance fonctionnelle Connectivité fonctionnelle

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Publications

Image document

Transcranial direct current stimulation modulates primate brain dynamics across states of consciousness

Guylaine Hoffner , Pablo Castro , Lynn Uhrig , Camilo Miguel Signorelli , Morgan Dupont et al.
eLife, 2025, 13, pp.RP101688. ⟨10.7554/eLife.101688⟩
Article dans une revue hal-05345720 v1

Transient brain activity dynamics discriminate levels of consciousness during anesthesia

Scott Ensel , Lynn Uhrig , Ayberk Ozkirli , Guylaine Hoffner , Jordy Tasserie et al.
Communications Biology, 2024, 7 (1), pp.716. ⟨10.1038/s42003-024-06335-x⟩
Article dans une revue hal-04616713 v1

Transglutaminase in neurological disease

Guylaine Hoffner , Philippe Djian
Oncotarget, 2017, 8 (34), pp.55772-55773. ⟨10.18632/oncotarget.19694⟩
Article dans une revue hal-03036731 v1

Identification of brain substrates of transglutaminase by functional proteomics supports its role in neurodegenerative diseases

William André , Isabelle Nondier , Maud Valensi , François Guillonneau , Christian Federici et al.
Neurobiology of Disease, 2017, 101, pp.40-58. ⟨10.1016/j.nbd.2017.01.007⟩
Article dans une revue hal-03036725 v1

Inclusions of R6/2 Mice Are Not Amyloid and Differ Structurally from Those of Huntington Disease Brain

William André , Christophe Sandt , Isabelle Nondier , Philippe Djian , Guylaine Hoffner
Analytical Chemistry, 2017, 89 (10), pp.5201-5209. ⟨10.1021/acs.analchem.6b04199⟩
Article dans une revue hal-03036727 v1

Polyglutamine Aggregation in Huntington Disease: Does Structure Determine Toxicity?

Guylaine Hoffner , Philippe Djian
Molecular Neurobiology, 2014, 52 (3), pp.1297-1314. ⟨10.1007/s12035-014-8932-1⟩
Article dans une revue hal-05346893 v1
Image document

Monomeric, oligomeric and polymeric proteins in Huntington disease and other diseases of polyglutamine expansion

Guylaine Hoffner , Philippe Djian
Brain Sciences, 2014, 4, pp.91-122. ⟨10.3390/brainsci4010091⟩
Article dans une revue hal-05348617 v1

Synchrotron-based infrared spectroscopy brings to light the structure of protein aggregates in neurodegenerative diseases

Guylaine Hoffner , William André , Christophe Sandt , Philippe Djian
Critical Reviews in Analytical Chemistry, 2014, 33 (4), ⟨10.1515/revac-2014-0016⟩
Article dans une revue hal-05346907 v1

Structure of Inclusions of Huntington’s Disease Brain Revealed by Synchrotron Infrared Microspectroscopy: Polymorphism and Relevance to Cytotoxicity

William André , Christophe Sandt , Paul Dumas , Philippe Djian , Guylaine Hoffner
Analytical Chemistry, 2013, 85 (7), pp.3765-3773. ⟨10.1021/ac400038b⟩
Article dans une revue hal-05348652 v1

Transglutaminase-Catalyzed Cross linking in Neurological Disease: from Experimental Evidence to Therapeutic Inhibition.

G. Hoffner , W. André , A. Vanhoutteghem , S. Souès , P. Djian
CNS Neurol Disord Drug Targets, 2009, epub ahead of print
Article dans une revue hal-00423444 v1

The end product of transglutaminase crosslinking: simultaneous quantitation of [Nepsilon-(gamma-glutamyl) lysine] and lysine by HPLC-MS3.

G. Hoffner , G. van Der Rest , P. M. Dansette , P. Djian
Analytical Biochemistry, 2009, 384 (2), pp.296-304. ⟨10.1016/j.ab.2008.09.039⟩
Article dans une revue istex hal-00347891 v1

Misfolding of proteins with a polyglutamine expansion is facilitated by proteasomal chaperones.

Erwann Rousseau , Rieko Kojima , Guylaine Hoffner , Philippe Djian , Anne Bertolotti
Journal of Biological Chemistry, 2008, epub ahead of print. ⟨10.1074/jbc.M806256200⟩
Article dans une revue hal-00347893 v1

[N(epsilon)-(gamma-glutamyl) lysine] as a potential biomarker in neurological diseases : New detection method and fragmentation pathways.

Guylaine Hoffner , Yannik Hoppilliard , Guillaume van Der Rest , Patrick Dansette , Philippe Djian et al.
Journal of Mass Spectrometry, 2008, 43 (4), pp.456-469. ⟨10.1002/jms.1331⟩
Article dans une revue istex hal-00203376 v1

Aggregation of expanded huntingtin in the brains of patients with Huntington disease

Guylaine Hoffner , Sylvie Souès , Philippe Djian
Prion, 2007, 1 (1), pp.26-31
Article dans une revue hal-00152974 v1

Purification of neuronal inclusions of patients with Huntington disease reveals a broad range of N-terminal fragments of expanded huntingtin and insoluble polymers

Guylaine Hoffner , Marie-Laure Island , Philippe Djian
Journal of Neurochemistry, 2005, 95, pp.125-136
Article dans une revue hal-00093080 v1

Transglutaminase and diseases of the central nervous system.

Guylaine Hoffner , Philippe Djian
Frontiers in Bioscience, 2005, 10, pp.3078-3092. ⟨10.2741/1764⟩
Article dans une revue hal-00093084 v1
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Oligomeric and polymeric aggregates formed by proteins containing expanded polyglutamine

S. Iuchi , Guylaine Hoffner , P. Verbeke , P. Djian , H. Green
Proceedings of the National Academy of Sciences of the United States of America, 2003, 100 (5), pp.2409-2414. ⟨10.1073/pnas.0437660100⟩
Article dans une revue hal-05348736 v1
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Protein aggregation in Huntington’s disease

Guylaine Hoffner , Philippe Djian
Biochimie, 2002, 84 (4), pp.273-278. ⟨10.1016/s0300-9084(02)01398-6⟩
Article dans une revue hal-05348770 v1

Advances in Enzymology

Guylaine Hoffner , Philippe Djian , William André , Amandine Vanhoutteghem
TRANSGLUTAMINASE IN EPIDERMIS AND NEUROLOGICAL DISEASE OR WHAT MAKES A GOOD CROSSLINKING SUBSTRATE, 78 (1), Wiley, 2011, Advances in Enzymology - and Related Areas of Molecular Biology, ⟨10.1002/9781118105771.ch3⟩
Chapitre d'ouvrage hal-05348697 v1