Isabelle BEHM-ANSMANT

60
Documents
Affiliations actuelles
  • ARN-RNP, structure-fonction-maturation (AREMS)
  • Ingénierie Moléculaire et Physiopathologie Articulaire (IMoPA)
  • Maturation des ARN et enzymologie moléculaire (MAEM)
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Publications

Publications

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Quantitative detection of 2’-O-methylated residues in non-coding RNAs using DNAzymes and quantitative RT-PCR

Valentyne Lebret-Kogey , Lilia Ayadi , Sylvain Maenner , Yuri Motorin , Isabelle Behm-Ansmant et al.

Biochimie, 2025, 237, pp.26-39. ⟨10.1016/j.biochi.2025.07.006⟩

Article dans une revue hal-05162861v1
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Multiomic profiling of new-onset kidney function decline: insights from the STANISLAS study cohort with a 20-year follow-up

Vincent Dupont , Constance Xhaard , Isabelle Behm-Ansmant , Emmanuel Bresso , Quentin Thuillier et al.

Clinical Kidney Journal, 2024, 17 (8), pp.sfae224. ⟨10.1093/ckj/sfae224⟩

Article dans une revue hal-04660216v1
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The Normal, the Radiosensitive, and the Ataxic in the Era of Precision Radiotherapy: A Narrative Review

Sandrine Pereira , Ester Orlandi , Sophie Deneuve , Amelia Barcellini , Agnieszka Chalaszczyk et al.

Cancers, 2022, 14 (24), pp.6252. ⟨10.3390/cancers14246252⟩

Article dans une revue (article de synthèse) hal-03906711v1
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Evaluation of a Functional Assay for Radiosensitivity in the Pediatric Prospective Cohort ARPEGE

G. Vogin , S. Pereira , E. Cérimele , M. Duclos , V. Scherrer et al.

International Journal of Radiation Oncology, Biology, Physics, 2022, 114 (3S), pp.S159. ⟨10.1016/j.ijrobp.2022.07.646⟩

Article dans une revue hal-03875371v1
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Fatty acid desaturase genetic variations and dietary omega-3 fatty acid intake associate with arterial stiffness

Magnus Bäck , Constance Xhaard , Raphael Rouget , Quentin Thuillier , Oscar Plunde et al.

European Heart Journal Open, 2022, pp.oeac016. ⟨10.1093/ehjopen/oeac016⟩

Article dans une revue hal-03613927v1
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Impact of natriuretic peptide polymorphisms on diastolic and metabolic function in a populational cohort: insights from the STANISLAS cohort

Constance Xhaard , Raphaël Rouget , Nicolas Vodovar , Edith Le Floch , Claire Dandine‐roulland et al.

ESC Heart Failure, 2021, ⟨10.1002/ehf2.13674⟩

Article dans une revue hal-03414759v1
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Implication of repeat insertion domains in the trans -activity of the long non-coding RNA ANRIL

Charbel Alfeghaly , Aymeric Sanchez , Raphael Rouget , Quentin Thuillier , Valérie Igel-Bourguignon et al.

Nucleic Acids Research, 2021, 49 (9), pp.4954-4970. ⟨10.1093/nar/gkab245⟩

Article dans une revue hal-03202552v1

Radiomics Method for the Differential Diagnosis of Radionecrosis Versus Progression after Fractionated Stereotactic Body Radiotherapy for Brain Oligometastasis

Liza Hettal , Anais Stefani , Julia Salleron , Florent Courrech , Isabelle Behm-Ansmant et al.

Radiation Research, 2020, 193 (5), pp.471. ⟨10.1667/RR15517.1⟩

Article dans une revue hal-02955312v1
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Substructure Analyzer: A User-Friendly Workflow for Rapid Exploration and Accurate Analysis of Cellular Bodies in Fluorescence Microscopy Images

Géraud Heckler , Christelle Aigueperse , Liza Hettal , Quentin Thuillier , Fabrice de Chaumont et al.

Journal of visualized experiments : JoVE, 2020, 161, ⟨10.3791/60990⟩

Article dans une revue hal-02955300v1
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Specific G-quadruplex ligands modulate the alternative splicing of Bcl-X

Carika Weldon , Justine G Dacanay , Vijay Gokhale , Peda venkat l Boddupally , Isabelle Behm-Ansmant et al.

Nucleic Acids Research, 2018, 46 (2), pp.886 - 896. ⟨10.1093/nar/gkx1122⟩

Article dans une revue hal-01738356v1

Deep Structural Analysis of RPAP3 and PIH1D1, Two Components of the HSP90 Co-chaperone R2TP Complex

Julien Henri , Marie-Eve Chagot , Maxime Bourguet , Yoann Abel , Guillaume Terral et al.

Structure, 2018, 26 (9), pp.1196-1209.e8. ⟨10.1016/j.str.2018.06.002⟩

Article dans une revue hal-01919243v1
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Contribution of protein Gar1 to the RNA-guided and RNA-independent rRNA:Ψ-synthase activities of the archaeal Cbf5 protein

Ryosuke Fujikane , Isabelle Behm-Ansmant , Anne-Sophie Tillault , Christine Loegler , Valérie Igel-Bourguignon et al.

Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-32164-0⟩

Article dans une revue hal-01879274v2
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Identification of G-quadruplexes in long functional RNAs using 7-deazaguanine RNA

Carika Weldon , Isabelle Behm-Ansmant , Laurence H Hurley , Glenn A Burley , Christiane Branlant et al.

Nature Chemical Biology, 2017, 13 (1), pp.18-20. ⟨10.1038/nCHeMBIO.2228⟩

Article dans une revue hal-01738347v1
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MicroRNA-29b Contributes to Collagens Imbalance in Human Osteoarthritic and Dedifferentiated Articular Chondrocytes

David Moulin , Veronique Salone , Meriem Koufany , Thomas Clément , Isabelle Behm-Ansmant et al.

BioMed Research International , 2017, 2017, pp.1 - 12. ⟨10.1155/2017/9792512⟩

Article dans une revue hal-01704545v1
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Enhanced SRSF5 Protein Expression Reinforces Lamin A mRNA Production in HeLa Cells and Fibroblasts of Progeria Patients

Valentin Vautrot , Christelle Aigueperse , Florence Oillo-Blanloeil , Sebastien Hupont , James Stevenin et al.

Human Mutation, 2016, 37 (3), pp.280-291. ⟨10.1002/humu.22945⟩

Article dans une revue istex hal-01451666v1

Tau exon 2 responsive elements deregulated in myotonic dystrophy type I are proximal to exon 2 and synergistically regulated by MBNL1 and MBNL2

C. Carpentier , D. Ghanem , F. J. Fernandez-Gomez , F. Jumeau , J. V. Philippe et al.

Biochimica et Biophysica Acta - Molecular Basis of Disease, 2014, 1842 (4), pp.654-664. ⟨10.1016/j.bbadis.2014.01.004⟩

Article dans une revue hal-01453196v1
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Analysis of Exonic Regions Involved in Nuclear Localization, Splicing Activity, and Dimerization of Muscleblind-like-1 Isoforms

Helene Tran , Nathalie Gourrier , Camille Lemercier-Neuillet , Claire-Marie Dhaenens , Audrey Vautrin et al.

Journal of Biological Chemistry, 2011, 286 (18), pp.16435 - 16446. ⟨10.1074/jbc.M110.194928⟩

Article dans une revue hal-01738403v1

A conserved splicing mechanism of the LMNA gene controls premature aging

Isabel Cristina Lopez-Mejia , Valentin Vautrot , Marion de Toledo , Isabelle Behm-Ansmant , Cyril Bourgeois et al.

Human Molecular Genetics, 2011, 20 (23), pp.4540-4555. ⟨10.1093/hmg/ddr385⟩

Article dans une revue hal-03034380v1
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Use of Specific Chemical Reagents for Detection of Modified Nucleotides in RNA

Isabelle Behm-Ansmant , Mark Helm , Yuri Motorin

Journal of Nucleic Acids , 2011, 2011, pp.1 - 17. ⟨10.4061/2011/408053⟩

Article dans une revue hal-01738372v1
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Antagonistic factors control the unproductive splicing of SC35 terminal intron

Natacha Dreumont , Sara Hardy , Isabelle Behm-Ansmant , Liliane Kister , Christiane Branlant et al.

Nucleic Acids Research, 2010, 38 (4), pp.1353 - 1366. ⟨10.1093/nar/gkp1086⟩

Article dans une revue hal-01738427v1
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RNA Sequence and Two-dimensional Structure Features Required for Efficient Substrate Modification by the Saccharomyces cerevisiae RNA:Ψ-Synthase Pus7p

Alan Urban , Isabelle Behm-Ansmant , Christiane Branlant , Yuri Motorin

Journal of Biological Chemistry, 2009, 284 (9), pp.5845 - 5858. ⟨10.1074/jbc.M807986200⟩

Article dans une revue hal-01738433v1
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P-Body Formation Is a Consequence, Not the Cause, of RNA-Mediated Gene Silencing

Ana Eulalio , Isabelle Behm-Ansmant , Daniel Schweizer , Elisa Izaurralde

Molecular and Cellular Biology, 2007, 27 (11), pp.3970-3981. ⟨10.1128/MCB.00128-07⟩

Article dans une revue hal-01738446v1
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The Saccharomyces cerevisiae Pus2 protein encoded by YGL063w ORF is a mitochondrial tRNA: 27/28-synthase

Isabelle Behm-Ansmant , Christiane Branlant , Yuri Motorin

RNA, 2007, 13 (10), pp.1641 - 1647. ⟨10.1261/rna.605607⟩

Article dans une revue hal-01738450v1
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mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes

Isabelle Behm-Ansmant , Jan Rehwinkel , Tobias Doerks , Alexander Stark , Elisa Izaurralde

Genes and Development, 2006, 20 (14), pp.1885 - 1898. ⟨10.1101/gad.1424106⟩

Article dans une revue hal-01738497v1

A previously unidentified activity of yeast and mouse RNA:pseudouridine synthases 1 (Pus1p) on tRNAs

I. Behm-Ansmant , Séverine Massenet , Françoise Immel , Jeffrey R Patton , Yuri Motorin et al.

RNA, 2006, 12 (8), pp.1583-1593. ⟨10.1261/rna.100806⟩

Article dans une revue hal-02279876v1
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A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing

Jan Rehwinkel , Isabelle Behm-Ansmant , David Gatfield , Elisa Izaurralde

RNA, 2005, 11 (11), pp.1640-1647. ⟨10.1261/rna.2191905⟩

Article dans une revue hal-01738499v1
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Pseudouridylation at Position 32 of Mitochondrial and Cytoplasmic tRNAs Requires Two Distinct Enzymes in Saccharomyces cerevisiae

Isabelle Behm-Ansmant , Henri H. Grosjean , Séverine Massenet , Yuri Motorin , Christiane Branlant

Journal of Biological Chemistry, 2004, 279 (51), pp.52998-53006. ⟨10.1074/jbc.M409581200⟩

Article dans une revue hal-01738505v1

Identification and Characterization of the tRNA:Ψ 31 -Synthase (Pus6p) of Saccharomyces cerevisiae

Isabelle Ansmant , Yuri Motorin , Séverine Massenet , Henri Grosjean , Christiane Branlant

Journal of Biological Chemistry, 2001, 276 (37), pp.34934-34940. ⟨10.1074/jbc.M103131200⟩

Article dans une revue hal-02279866v1

Identification of the Saccharomyces cerevisiae RNA:pseudouridine synthase responsible for formation of 2819 in 21S mitochondrial ribosomal RNA

I. Ansmant , S. Massenet , H. Grosjean , Y. Motorin , C. Branlant

Nucleic Acids Research, 2000, 28 (9), pp.1941-1946. ⟨10.1093/nar/28.9.1941⟩

Article dans une revue hal-02279850v1

The first determination of pseudouridine residues in 23S ribosomal RNA from hyperthermophilic Archaea Sulfolobus acidocaldarius

Séverine Massenet , Isabelle Ansmant , Yuri Motorin , Christiane Branlant

FEBS Letters, 1999, 462 (1-2), pp.94-100. ⟨10.1016/s0014-5793(99)01524-0⟩

Article dans une revue istex hal-02279844v1

Long non-coding RNAs: promising therapeutic targets for inflammatory diseases?

Isabelle Behm-Ansmant

RNA therapeutics: from concept to clinic, Jun 2025, Worcester (USA), United States

Poster de conférence hal-05407066v1
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Triplex Decoy oligonucleotides as modulators of long non-coding RNA activities.

Lilia Ayadi , Aymeric Sanchez , Guillaume Grosjean , Charbel Alfeghaly , Franceline Reynaud et al.

13th SifrARN, Nov 2024, Lyon, France

Poster de conférence hal-05407027v1
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Unraveling the implication of the long non-coding RNA ANRIL in alternative splicing and its impacts on Cancer

Julien Lhuillier , Christelle Aigueperse , Aymeric Sanchez , Lilia Ayadi , Charbel Alfeghaly et al.

13th SifrARN (Structure, Intégration, Fonction et Réactivité de l’ARN), Nov 2024, Lyon, France.

Poster de conférence hal-05407019v1

Role of the long non-coding RNA ANRIL in chromatin landscape regulation and its potential association with disease.

Aymeric Sanchez , Julien Lhuillier , Lilia Ayadi , Charbel Alfeghaly , Wassim Rhaloussi et al.

13th SifrARN, Nov 2024, Lyon, France

Poster de conférence hal-05407052v1
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The lncRNA ANRIL-induced gene modulation depends on its Exon21 enriched in Transposable Elements

Aymeric Sanchez , Charbel Alfeghaly , Lilia Ayadi , Wassim Rhalloussi , Quentin Thuillier et al.

12th SifrARN, Oct 2022, Bordeaux, France

Poster de conférence hal-04577641v1

Molecular dissection of lncRNA activities: ANRIL as Model System

Charbel Alfeghaly , Valentin Vautrot , Virginie Marchand , Yuri Motorin , Isabelle Behm-Ansmant et al.

24th Annual Meeting of the RNA society, Jun 2019, Cracovie, Poland

Poster de conférence hal-02968492v1

Investigation of RNA biomarkers predictive of skin radio-induced fibrosis

Liza Hettal , Cerimele Elise , Nathalie Rouard , Guillaume Vogin , Isabelle Behm-Ansmant

EMBO-FEBS course on Molecular mechanisms of tissue injury, repair and fibrosis, May 2019, Spetses Island, Greece

Poster de conférence hal-02968496v1

Microarray Analysis of Whole-Transcriptome RNAs Including Non-Coding RNAs

Quentin Thuillier , Isabelle Behm-Ansmant

Small Non-Coding RNAs: Methods and Protocols, 2300, pp.143-164, 2021, ⟨10.1007/978-1-0716-1386-3_14⟩

Chapitre d'ouvrage hal-03201496v1

Fluorescence In Situ Hybridization of Small Non-Coding RNAs

Valentin Vautrot , Géraud Heckler , Christelle Aigueperse , Isabelle Behm-Ansmant

Small Non-Coding RNAs: Methods and Protocols, pp.73-85, 2021, ⟨10.1007/978-1-0716-1386-3_8⟩

Chapitre d'ouvrage hal-03201498v1

Non-Coding RNA Silencing in Mammalian Cells by Antisense LNA GapmeRs Transfection

Charbel Alfeghaly , Christelle Aigueperse , Sylvain Maenner , Isabelle Behm-Ansmant

Small Non-Coding RNAs: Methods and Protocols, 2300, pp.31-37, 2021, ⟨10.1007/978-1-0716-1386-3_4⟩

Chapitre d'ouvrage hal-03201499v1

Study of Genome-Wide Occupancy of Long Non-Coding RNAs Using Chromatin Isolation by RNA Purification (ChIRP)

Charbel Alfeghaly , Isabelle Behm-Ansmant , Sylvain Maenner

Small Non-Coding RNAs: Methods and Protocols, 2300, pp.107-117, 2021, ⟨10.1007/978-1-0716-1386-3_11⟩

Chapitre d'ouvrage hal-03201497v1

Enhanced Probe-Based RT-qPCR Quantification of MicroRNAs Using Poly(A) Tailing and 5′ Adaptor Ligation

Valentin Vautrot , Isabelle Behm-Ansmant

Methods in Molecular Biology, 2065, pp.39-54, 2020, ⟨10.1007/978-1-4939-9833-3_4⟩

Chapitre d'ouvrage hal-02517653v1

Fluorescence In Situ Hybridization of Small Non-Coding RNAs

Valentin Vautrot , Christelle Aigueperse , Christiane Branlant , Isabelle Behm-Ansmant

Small Non-Coding RNAs: Methods and Protocols, 1296, Springer New York, pp.73-83, 2015, Methods in Molecular Biology, ⟨10.1007/978-1-4939-2547-6_8⟩

Chapitre d'ouvrage hal-05443390v1

Study of RNA-Protein Interactions and RNA Structure in Ribonucleoprotein Particles (RNPs)

Virginie Marchand , Annie Mougin , Agnès Méreau , Isabelle Behm-Ansmant , Yuri Motorin et al.

Roland K. Hartmann; Albrecht Bindereif; Astrid Schön; Eric Westhof. Handbook of RNA Biochemistry: Second, Completely Revised and Enlarged Edition, Wiley-VCH Verlag GmbH & Co. KGaA, pp.975-1016, 2014, 9783527327645. ⟨10.1002/9783527647064.ch44⟩

Chapitre d'ouvrage hal-01957954v1

Molecular dissection of lncRNA activities: ANRIL as Model System

Charbel Alfeghaly , Valentin Vautrot , Virginie Marchand , Yuri Motorin , Isabelle Behm-Ansmant et al.

Bermuda Principles: Impact on Splicing 3rd Annual Conference, Feb 2019, Southampton, Bermuda

Communication dans un congrès hal-02968414v1

Molecular dissection of lncRNA activities: ANRIL as Model System

Charbel Alfeghaly , Valentin Vautrot , Virginie Marchand , Yuri Motorin , Isabelle Behm-Ansmant et al.

11th sifrARN, Nov 2018, Vandoeuvre-les-Nancy, France

Communication dans un congrès hal-02968425v1

Changes of phosphorylation drive alternative splicing modulation by mild heat shock in human cells

Christelle Aigueperse , Valentin Vautrot , Luisa Vigevani , Papasaikas Panegiotis , Nathalie Nicot et al.

11th sifrARN, Nov 2018, Vandoeuvre-les-Nancy, France

Communication dans un congrès hal-02968400v1

Impact of culture conditions on the behavior of mesenchymal stem cells: choosing critical parameters related to cell quality

Naceur Charif , Meriem El Ouafy , Laurie Targa , Xing Liu , Audrey Fortunat Zeh Eto'O et al.

8th InternationalSymposium China-Europe Stem cells and regenerative medicine, Jun 2018, Wuhan, China

Communication dans un congrès hal-02973631v1

Changes of SF3B1 phosphorylation status participate to alternative splicing modulation by mild heat shock

Christelle Aigueperse , Valentin Vautrot , Luisa Vigevani , Papasaikas Panegiotis , Nathalie Nicot et al.

Bermuda Principles: Impact on Splicing 2nd Annual Conference, Feb 2018, Southampton, Bermuda

Communication dans un congrès hal-02968429v1

Crystal structure of the RPAP3-PIH1D1 cochaperones complex and regulation of the R2TP-Hsp90 machinery during macromolecular complex assembly

Julien Henri , Marie-Eve Chagot , Christelle Aigueperse , Florian Georgescauld , Rénette Saint-Fort et al.

The 9th International Conference on the Hsp90 Chaperone Machine, Oct 2018, Leysin, Switzerland

Communication dans un congrès hal-04342574v1

Towards the understanding of the mechanisms responsible for alternative splicing modulation by mild heat shock

Christelle Aigueperse , Valentin Vautrot , Luisa Vigevani , Papasaikas Panegiotis , Nathalie Nicot et al.

9th Bordeaux RNA Club symposium, Jun 2017, Bordeaux, France

Communication dans un congrès hal-02968433v1

SR and hnRNP proteins regulate HIV-1 multiplication by modulating mRNA splicing and translation

Lilia Ayadi , Georges Khoury , Jean-Michel Saliou , Sarah Cianferani-Sanglier , Alain Vandorsselaer et al.

22nd Annual Meeting of the RNA Society, May 2017, Prague, Czech Republic

Communication dans un congrès hal-02968438v1

Non-coding RNAs and mRNA splicing events as biomarkers of diseases and cell control quality tools, application to heart failure prevention

Virginie Marchand , Valentin Vautrot , Gired Nicolas , Faiez Zannad , Patrick Rossignol et al.

6th International Symposium Europe-China, Jul 2016, Nancy, France

Communication dans un congrès hal-02968456v1

RNA as MCS aging biomarkers : pertinence for regenerative medicine

N Charif, , Yy Li, , T Kaoma, , L Vallar, , Yp Li, et al.

6th International Symposium Europe-China, Jul 2016, Nancy, France

Communication dans un congrès hal-01722952v1

RNM as MCS aging biomarkers : pertinence for regenerative medicine

Naceur Charif , Li, Yy , T Kaoma, , Vallar, L , Li, Yp et al.

6th International Symposium Europe-China, Jul 2016, Nancy, France

Communication dans un congrès hal-03033120v1

SR and hnRNP proteins regulate HIV-1 multiplication by modulating mRNA splicing and translation

Lilia Ayadi , Georges Khoury , Jean-Michel Saliou , Sarah Cianferani-Sanglier , Alain Vandorsselaer et al.

4th Post-EURASNET Meeting, Sep 2016, Poznan, Poland

Communication dans un congrès hal-02968442v1

Specific G-quadruplex ligands regulate the alternative splicing of Bcl-x

Carika Weldon , Isabelle Behm-Ansmant , M. Vogler , Vijay Gokhale , Glenn A Burley et al.

21st Annual Meeting of the RNA Society, Jun 2016, Kyoto, Japan

Communication dans un congrès hal-02968462v1