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MUC1 Drives the Progression and Chemoresistance of Clear Cell Renal Carcinomas
Emma Bourdon
,
Thomas Swierczewski
,
Marine Goujon
,
Nihad Boukrout
,
Sandy Fellah
et al.
Article dans une revue
inserm-04479812
v1
|
|
Emerging paradigms and recent progress in targeting ErbB in cancers
Nicolas Stoup
,
Maxime Liberelle
,
Nicolas Lebegue
,
Isabelle Van Seuningen
Article dans une revue
(article de synthèse)
hal-04621567
v1
|
|
A novel anti-galectin-9 immunotherapy limits the early progression of pancreatic neoplastic lesions in transgenic mice
Alexandre Quilbe
,
Rami Mustapha
,
Belinda Duchêne
,
Abhishek Kumar
,
Elisabeth Werkmeister
et al.
Article dans une revue
hal-04469183
v1
|
|
ProNGF promotes brain metastasis through TrkA/EphA2 induced Src activation in triple negative breast cancer cells
Julien Cicero
,
Sarah Trouvilliez
,
Martine Palma
,
Gaetan Ternier
,
Laurine Decoster
et al.
Article dans une revue
hal-04334490
v2
|
|
Metabolism of pancreatic neuroendocrine tumors: what can omics tell us?
Arnaud Jannin
,
Anne-Frédérique Dessein
,
Christine Do Cao
,
Marie-Christine Vantyghem
,
Benjamin Chevalier
et al.
Article dans une revue
hal-04273585
v1
|
|
A Double-Negative Feedback Interaction between miR-21 and PPAR-α in Clear Renal Cell Carcinoma
Marine Goujon
,
Justine Woszczyk
,
Kelly Gaudelot
,
Thomas Swierczewski
,
Sandy Fellah
et al.
Article dans une revue
inserm-03729282
v1
|
|
TRPM7 Modulates Human Pancreatic Stellate Cell Activation.
Julie Auwercx
,
Philippe Kischel
,
Thibaut Lefebvre
,
Nicolas Jonckheere
,
Alison Vanlaeys
et al.
Article dans une revue
hal-03740502
v1
|
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The EGF Domains of MUC4 Oncomucin Mediate HER2 Binding Affinity and Promote Pancreatic Cancer Cell Tumorigenesis
Nicolas Stoup
,
Maxime Liberelle
,
Céline Schulz
,
Sumeyye Cavdarli
,
Romain Vasseur
et al.
Article dans une revue
hal-03641795
v1
|
|
Antagonistic Roles of the Tumor Suppressor miR-210-3p and Oncomucin MUC4 Forming a Negative Feedback Loop in Pancreatic Adenocarcinoma
Nihad Boukrout
,
Mouloud Souidi
,
Fatima Lahdaoui
,
Belinda Duchêne
,
Bernadette Neve
et al.
Article dans une revue
hal-03777017
v1
|
|
A new pancreatic adenocarcinoma‐derived organoid model of acquired chemoresistance to FOLFIRINOX: first insight of the underlying mechanisms
Elsa Hadj Bachir
,
Charles Poiraud
,
Sonia Paget
,
Nicolas Stoup
,
Soumaya El Moghrabi
et al.
Article dans une revue
hal-03369738
v2
|
|
Analysis of the proximal promoter of the human colon-specific B4GALNT2 (Sda synthase) gene: B4GALNT2 is transcriptionally regulated by ETS1
Cindy Wavelet-Vermuse
,
Sophie Groux-Degroote
,
Dorothée Vicogne
,
Virginie Cogez
,
Giulia Venturi
et al.
Article dans une revue
hal-03345208
v1
|
|
Mucin expression, epigenetic regulation and patient survival: A toolkit of prognostic biomarkers in epithelial cancers
Nicolas Jonckheere
,
Audrey Vincent
,
Bernadette Neve
,
Isabelle van Seuningen
Article dans une revue
hal-03294583
v1
|
|
Mg2+ Transporters in Digestive Cancers
Julie Auwercx
,
Pierre Rybarczyk
,
Philippe Kischel
,
Isabelle Dhennin-Duthille
,
Denis Chatelain
et al.
Article dans une revue
hal-03195960
v1
|
|
Fabricating Silicon Resonators for Analysing Biological Samples
Momoko Kumemura
,
Deniz Pekin
,
Vivek Anand Menon
,
Isabelle van Seuningen
,
Dominique Collard
et al.
Article dans une revue
(article de synthèse)
hal-03501246
v1
|
|
Loss of Polycomb Repressive Complex 2 Function Alters Digestive Organ Homeostasis and Neuronal Differentiation in Zebrafish
Ludivine Raby
,
Pamela Völkel
,
Shaghayegh Hasanpour
,
Julien Cicero
,
Robert-Alain Toillon
et al.
Article dans une revue
hal-04488645
v1
|
|
MUC1 Mitigates Renal Injury and Inflammation in Endotoxin-Induced Acute Kidney Injury by Inhibiting the TLR4-MD2 Axis and Reducing Pro-inflammatory Macrophages Infiltration
Jean-Baptiste Gibier
,
Thomas Swierczewski
,
Marie Csanyi
,
Brigitte Hemon
,
Francois Glowacki
et al.
Article dans une revue
hal-03379151
v1
|
|
Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells
Marjolaine Bauzone
,
Mouloud Souidi
,
Anne-Frédérique Dessein
,
Maxence Wisztorski
,
Audrey Vincent
et al.
Article dans une revue
hal-04284692
v1
|
|
EGF-Containing Membrane-Bound Mucins: A Hidden ErbB2 Targeting Pathway?
Maxime Liberelle
,
Nicolas Jonckheere
,
Patricia Melnyk
,
Isabelle van Seuningen
,
Nicolas Lebègue
Article dans une revue
hal-02955348
v1
|
|
Galectin-3 modulates epithelial cell adaptation to stress at the ER-mitochondria interface
Lucie Coppin
,
Arnaud Jannin
,
Emilie Ait Yahya
,
Caroline Thuillier
,
Céline Villenet
et al.
Article dans une revue
hal-03060582
v1
|
|
Unsupervised Hierarchical Clustering of Pancreatic Adenocarcinoma Dataset from TCGA Defines a Mucin Expression Profile that Impacts Overall Survival
Nicolas Jonckheere
,
Julie Auwercx
,
Elsa Hadj Bachir
,
Lucie Coppin
,
Nihad Boukrout
et al.
Article dans une revue
hal-03003452
v2
|
|
Long non-coding RNAs: the tentacles of chromatin remodeler complexes
Bernadette Neve
,
Nicolas Jonckheere
,
Audrey Vincent
,
Isabelle van Seuningen
Article dans une revue
hal-03195963
v1
|
|
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer
Maria Paula Roberti
,
Satoru Yonekura
,
Connie P. M. Duong
,
Marion Picard
,
Gladys Ferrere
et al.
Article dans une revue
hal-03313676
v1
|
|
Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia.
Mélanie Lambert
,
M Alioui
,
Samy Jambon
,
Sabine Depauw
,
Isabelle Van Seuningen
et al.
Article dans une revue
(article de synthèse)
hal-04549198
v1
|
|
Direct and Indirect Targeting of HOXA9 Transcription Factor in Acute Myeloid Leukemia.
Mélanie Lambert
,
Meryem Alioui
,
Samy Jambon
,
Sabine Depauw
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-02358430
v1
|
|
Fine-tuning autophagy in pancreatic adenocarcinoma: full blockage is required
Nicolas Jonckheere
,
Isabelle van Seuningen
Article dans une revue
inserm-02341315
v1
|
|
Colon cancer stemness as a reversible epigenetic state: Implications for anticancer therapies
Audrey Vincent
,
Aïcha Ouelkdite-Oumouchal
,
Mouloud Souidi
,
Julie Leclerc
,
Bernadette Neve
et al.
Article dans une revue
inserm-02351996
v1
|
|
MUC4-ErbB2 Oncogenic Complex: Binding studies using Microscale Thermophoresis
Maxime Liberelle
,
Romain Magnez
,
Xavier Thuru
,
Yamina Bencheikh
,
Séverine Ravez
et al.
Article dans une revue
hal-02407901
v1
|
|
Gemcitabine‐induced epithelial‐mesenchymal transition‐like changes sustain chemoresistance of pancreatic cancer cells of mesenchymal‐like phenotype
Mehdi El Amrani
,
François Corfiotti
,
Matthieu Corvaisier
,
Romain Vasseur
,
Maxence Fulbert
et al.
Article dans une revue
inserm-02352000
v1
|
|
TGF-βRII Knock-down in Pancreatic Cancer Cells Promotes Tumor Growth and Gemcitabine Resistance. Importance of STAT3 Phosphorylation on S727
Vincent Drubay
,
Nicolas Skrypek
,
Lucie Cordiez
,
Romain Vasseur
,
Céline Schulz
et al.
Article dans une revue
inserm-02341320
v1
|
|
Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.
Nicolas Jonckheere
,
Isabelle van Seuningen
Article dans une revue
hal-02341297
v1
|
|
Epigenetic Regulation by lncRNAs: An Overview Focused on UCA1 in Colorectal Cancer
Bernadette Neve
,
Nicolas Jonckheere
,
Audrey Vincent
,
Isabelle van Seuningen
Article dans une revue
inserm-02341333
v1
|
|
Lepidic predominant adenocarcinoma and invasive mucinous adenocarcinoma of the lung exhibit specific mucin expression in relation with oncogenic drivers
Michaël Duruisseaux
,
Martine Antoine
,
Nathalie Rabbe
,
Anita Rodenas
,
Anne Mc Leer-Florin
et al.
Article dans une revue
hal-01535623
v1
|
|
Depletion of MUC5B mucin in gastrointestinal cancer cells alters their tumorigenic properties: implication of the Wnt/β-catenin pathway
Fatima Lahdaoui
,
Mathieu Messager
,
Audrey Vincent
,
Flora Hec
,
Anne Gandon
et al.
Article dans une revue
inserm-02341337
v1
|
|
Flagellin-Mediated Protection against Intestinal Yersinia pseudotuberculosis Infection Does Not Require Interleukin-22.
Rémi Porte
,
Laurye van Maele
,
Natalia Muñoz-Wolf
,
Benoit Foligné
,
Laure Dumoutier
et al.
Article dans une revue
inserm-01529315
v1
|
|
Targeting miR-21 decreases expression of multi-drug resistant genes and promotes chemosensitivity of renal carcinoma
Kelly Gaudelot
,
Jean-Baptiste Gibier
,
Nicolas Pottier
,
Brigitte Hémon
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-03313744
v1
|
|
Galectin-3 is a non-classic RNA binding protein that stabilizes the mucin MUC4 mRNA in the cytoplasm of cancer cells
Lucie Coppin
,
Audrey Vincent
,
Frédéric Frénois
,
Belinda Duchêne
,
Fatima Lahdaoui
et al.
Article dans une revue
hal-01534451
v1
|
|
Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase
Jean-Baptiste Gibier
,
Brigitte Hemon
,
Melanie Fanchon
,
Kelly Gaudelot
,
Nicolas Pottier
et al.
Article dans une revue
inserm-01833348
v1
|
|
The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting
Nicolas Jonckheere
,
Romain Vasseur
,
Isabelle Van Seuningen
Article dans une revue
inserm-02341607
v1
|
|
The serrated neoplasia pathway of colorectal tumors: Identification of MUC5AC hypomethylation as an early marker of polyps with malignant potential
Florence Renaud
,
Christophe Mariette
,
Audrey Vincent
,
Agnès Wacrenier
,
Vincent Maunoury
et al.
Article dans une revue
hal-02905823
v1
|
|
Hemidesmosome integrity protects the colon against colitis and colorectal cancer
Adèle de Arcangelis
,
Hussein Hamade
,
Fabien Alpy
,
Sylvain Normand
,
Emilie Bruyère
et al.
Article dans une revue
hal-01538539
v1
|
|
Regulation of cellular quiescence by YAP/TAZ and Cyclin E1 in colon cancer cells: Implication in chemoresistance and cancer relapse
Matthieu Corvaisier
,
Marjolaine Bauzone
,
François Corfiotti
,
Florence Renaud
,
Mehdi El Amrani
et al.
Article dans une revue
hal-03313749
v1
|
|
Suitability of Surgically Induced Chronic Reflux in Rats for Studying Esophageal Carcinogenesis
Caroline Gronnier
,
Guillaume Piessen
,
Emmanuelle Leteurtre
,
Isabelle van Seuningen
,
Christophe Mariette
Article dans une revue
hal-03313754
v1
|
|
Targeting MUC4 in pancreatic cancer: miRNAs
Nicolas Jonckheere
,
Fatima Lahdaoui
,
Isabelle van Seuningen
Article dans une revue
hal-02905858
v1
|
|
The oncogenic receptor ErbB2 modulates gemcitabine and irinotecan/SN-38 chemoresistance of human pancreatic cancer cells via hCNT1 transporter and multidrug-resistance associated protein MRP-2
Nicolas Skrypek
,
Romain Vasseur
,
Audrey Vincent
,
Bélinda Duchêne
,
Isabelle van Seuningen
et al.
Article dans une revue
inserm-02341515
v1
|
|
MUC5AC hypomethylation is a predictor of microsatellite instability independently of clinical factors associated with colorectal cancer
Florence Renaud
,
Audrey Vincent
,
Christophe Mariette
,
Michel Crépin
,
Laurence Stechly
et al.
Article dans une revue
hal-02905819
v1
|
|
The mucin MUC4 is a transcriptional and post-transcriptional target of K-ras oncogene in pancreatic cancer. Implication of MAPK/AP-1, NF-κB and RalB signaling pathways
Romain Vasseur
,
Nicolas Skrypek
,
Belinda Duchêne
,
Florence Renaud
,
Daniel Martínez-Maqueda
et al.
Article dans une revue
hal-02906327
v1
|
|
Cryosectioning the intestinal crypt-villus axis: An ex vivo method to study the dynamics of epigenetic modifications from stem cells to differentiated cells
Audrey Vincent
,
Catherine Kazmierczak
,
Belinda Duchêne
,
Nicolas Jonckheere
,
Emmanuelle Leteurtre
et al.
Article dans une revue
hal-02905864
v1
|
|
Micro-RNAs miR-29a and miR-330-5p function as tumor suppressors by targeting the MUC1 mucin in pancreatic cancer cells
Solange Tréhoux
,
Fatima Lahdaoui
,
Yannick Delpu
,
Florence Renaud
,
Emmanuelle Leteurtre
et al.
Article dans une revue
hal-02905657
v1
|
|
Overexpression of chemokine receptor CXCR2 and ligand CXCL7 in liver metastases from colon cancer is correlated to shorter disease-free and overall survival
Thibault Desurmont
,
Nicolas Skrypek
,
Alain Duhamel
,
Nicolas Jonckheere
,
Guillaume Millet
et al.
Article dans une revue
hal-02954490
v1
|
|
MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway
Audrey Bouillez
,
Viviane Gnemmi
,
Kelly Gaudelot
,
Brigitte Hemon
,
Bélinda Ringot
et al.
Oncotarget, 2014
Article dans une revue
hal-02905860
v1
|
|
Mucins and tumor resistance to chemotherapeutic drugs
Nicolas Jonckheere
,
Nicolas Skrypek
,
Isabelle Van Seuningen
Article dans une revue
inserm-02341531
v1
|
|
Of autophagy and in vivo pancreatic carcinogenesis: The p53 status matters!
Nicolas Jonckheere
,
Audrey Vincent
,
Isabelle Van Seuningen
Article dans une revue
inserm-02341594
v1
|
|
The MUC1 oncomucin regulates pancreatic cancer cell biological properties and chemoresistance. Implication of p42-44 MAPK, Akt, Bcl-2 and MMP13 pathways
Solange Tréhoux
,
Bélinda Duchêne
,
Nicolas Jonckheere
,
Isabelle van Seuningen
Article dans une revue
hal-02905690
v1
|
|
Combined NADPH Oxidase 1 and Interleukin 10 Deficiency Induces Chronic Endoplasmic Reticulum Stress and Causes Ulcerative Colitis-Like Disease in Mice
Xavier Tréton
,
Eric Pedruzzi
,
Cécile Guichard
,
Yannick Ladeiro
,
Shirin Sedghi
et al.
Article dans une revue
hal-03313755
v1
|
|
Helicobacter pylori urease and flagellin alter mucin gene expression in human gastric cancer cells
Michael Perrais
,
Christel Rousseaux
,
Marie-Paule Ducourouble
,
René Courcol
,
Pascal Vincent
et al.
Article dans une revue
hal-02905802
v1
|
|
Comment on: Functional MUC4 suppress epithelial-mesenchymal transition in lung adenocarcinoma metastasis. Gao L, Liu J, Zhang B, Zhang H, Wang D, Zhang T, Liu Y, Wang C. Tumour Biol. 2013, in press
Nicolas Jonckheere
,
Isabelle van Seuningen
Article dans une revue
inserm-02371186
v1
|
|
MUC1-C nuclear localization drives invasiveness of renal cancer cells through a sheddase/gamma secretase dependent pathway
Audrey Bouillez
,
Viviane Gnemmi
,
Kelly Gaudelot
,
Brigitte Hémon
,
Bélinda Ringot
et al.
Article dans une revue
hal-03313775
v1
|
|
Epigenetic silencing of EYA2 in pancreatic adenocarcinomas promotes tumor growth
Audrey Vincent
,
Seung-Mo Hong
,
Chaoxin Hu
,
Noriyuki Omura
,
Angela Young
et al.
Article dans une revue
hal-02905879
v1
|
|
MUC1 drives epithelial–mesenchymal transition in renal carcinoma through Wnt/β-catenin pathway and interaction with SNAIL promoter
Viviane Gnemmi
,
Audrey Bouillez
,
Kelly Gaudelot
,
Brigitte Hémon
,
Bélinda Ringot
et al.
Article dans une revue
hal-03313770
v1
|
|
The MUC1 mucin regulates the tumorigenic properties of human esophageal adenocarcinomatous cells
Caroline Gronnier
,
Emilie Bruyère
,
Fatima Lahdaoui
,
Nicolas Jonckheere
,
Michael Perrais
et al.
Article dans une revue
hal-02905652
v1
|
|
MUC1 Expression in Papillary Thyroid Carcinoma Is Associated with BRAF Mutation and Lymph Node Metastasis; the Latter is the Most Important Risk Factor of Relapse
Florence Renaud
,
Viviane Gnemmi
,
Patrick Devos
,
Sébastien Aubert
,
Michel Crépin
et al.
Article dans une revue
hal-03313761
v1
|
|
Membrane-bound mucin modular domains: from structure to function.
Nicolas Jonckheere
,
Nicolas Skrypek
,
Frédéric Frénois
,
Isabelle van Seuningen
Article dans une revue
inserm-00807818
v1
|
|
Estradiol Represses the GD3 Synthase Gene ST8SIA1 Expression in Human Breast Cancer Cells by Preventing NFκB Binding to ST8SIA1 Promoter.
Marie Bobowski
,
Audrey Vincent
,
Agata Steenackers
,
Florent Colomb
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-00819798
v1
|
|
The MUC4 mucin mediates gemcitabine resistance of human pancreatic cancer cells via the Concentrative Nucleoside Transporter family.
Nicolas Skrypek
,
Bélinda Duchêne
,
Mohamed Hebbar
,
Emmanuelle Leteurtre
,
Isabelle van Seuningen
et al.
Article dans une revue
inserm-00807837
v1
|
|
Operatively induced chronic reflux in rats: A suitable model for studying esophageal carcinogenesis?
Caroline Gronnier
,
Emilie Bruyère
,
Guillaume Piessen
,
Nicolas Briez
,
Jérôme Bot
et al.
Article dans une revue
hal-02905869
v1
|
|
Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon
Mirte Streppel
,
Audrey Vincent
,
Radha Mukherjee
,
Nathaniel Campbell
,
Shih-Hsun Chen
et al.
Article dans une revue
hal-03313777
v1
|
|
Mucin Muc2 Deficiency and Weaning Influences the Expression of the Innate Defense Genes Reg3b, Reg3c and Angiogenin-4
Nanda Burger-van Paassen
,
Linda M P Loonen
,
Janneke Witte-Bouma
,
Anita Korteland-van Male
,
Adrianus C J M de Bruijn
et al.
Article dans une revue
hal-02905863
v1
|
|
Membrane-bound mucin modular domains: From structure to function
Nicolas Jonckheere
,
Frédéric Frénois
,
Isabelle van Seuningen
,
Nicolas Q1
,
Nicolas Skrypek
et al.
Article dans une revue
hal-02905700
v1
|
|
GATA-4/-6 and HNF-1/-4 families of transcription factors control the transcriptional regulation of the murine Muc5ac mucin during stomach development and in epithelial cancer cells.
Nicolas Jonckheere
,
Audrey Vincent
,
Hélène Franquet-Ansart
,
Janneke Witte-Bouma
,
Anita Korteland-van Male
et al.
Article dans une revue
inserm-00807845
v1
|
|
The mucin MUC4 and its membrane partner ErbB2 regulate biological properties of human CAPAN-2 pancreatic cancer cells via different signalling pathways.
Nicolas Jonckheere
,
Nicolas Skrypek
,
Johann Merlin
,
Anne Frédérique Dessein
,
Patrick Dumont
et al.
Article dans une revue
inserm-00807830
v1
|
|
On the epigenetic origin of cancer stem cells
Audrey Vincent
,
Isabelle van Seuningen
Article dans une revue
hal-02905665
v1
|
|
Tif1γ Suppresses Murine Pancreatic Tumoral Transformation by a Smad4-Independent Pathway
David Vincent
,
Johann Gout
,
Nicolas Chuvin
,
Vanessa Arfi
,
Roxane M. Pommier
et al.
Article dans une revue
hal-02954464
v1
|
|
The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors.
Nicolas Jonckheere
,
Amélie Velghe
,
Marie-Paule Ducourouble
,
Marie-Christine Copin
,
Ingrid B. Renes
et al.
Article dans une revue
inserm-00807850
v1
|
|
Colonic gene expression patterns of mucin muc2 knockout mice reveal various phases in colitis development1
Peng Lu
,
Nanda Burger-van Paassen
,
Maria van Der Sluis
,
Janneke Witte-Bouma
,
Jean-Pierre Kerckaert
et al.
Article dans une revue
hal-03313788
v1
|
|
Colitis development during the suckling-weaning transition in mucin Muc2-deficient mice
Nanda Burger-van Paassen
,
Maria van Der Sluis
,
Janneke Bouma
,
Anita Korteland-van Male
,
Peng Lu
et al.
Article dans une revue
hal-03313786
v1
|
|
Complex interplay between {beta}-catenin signalling and Notch effectors in intestinal tumorigenesis.
Grégory Peignon
,
Aurélie Durand
,
Wulfran Cacheux
,
Olivier Ayrault
,
Benoît Terris
et al.
Article dans une revue
inserm-00553865
v1
|
|
The MUC4 membrane-bound mucin regulates esophageal cancer cell proliferation and migration properties: Implication for S100A4 protein
Emilie Bruyère
,
Nicolas Jonckheere
,
Frédéric Frénois
,
Christophe Mariette
,
Isabelle van Seuningen
Article dans une revue
hal-02905689
v1
|
|
Transcript Profiling of Elf5 +/2 Mammary Glands during Pregnancy Identifies Novel Targets of Elf5
Renee L Rogers
,
Isabelle van Seuningen
,
Jodee Gould
,
Paul J Hertzog
,
Matthew J Naylor
et al.
Article dans une revue
hal-02905862
v1
|
|
Mucins and Pancreatic Cancer
Nicolas Jonckheere
,
Nicolas Skrypek
,
Isabelle van Seuningen
Article dans une revue
inserm-00807873
v1
|
|
Signal Pathway of 17β-Estradiol–Induced MUC5B Expression in Human Airway Epithelial Cells
Hye Joung Choi
,
Yoo-Sam Chung
,
Hyun Jik Kim
,
Uk Yeol Moon
,
Yeon Ho Choi
et al.
Article dans une revue
hal-03313791
v1
|
|
Glycosylation pattern of brush border-associated glycoproteins in enterocyte-like cells: involvement of complex-type N-glycans in apical trafficking
Willy Morelle
,
Laurence Stechly
,
Sabine Andre
,
Isabelle van Seuningen
,
Nicole Porchet
et al.
Article dans une revue
hal-02905705
v1
|
|
Intrauterine growth restriction alters postnatal colonic barrier maturation in rats
Pascale Fanca-Berthon
,
Catherine Michel
,
Anthony Pagniez
,
Martine Rival
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-02662866
v1
|
|
Clinical impact of MUC1 and MUC4 expression in Barrett-associated oesophageal adenocarcinoma
G. Piessen
,
A. Wacrenier
,
N. Briez
,
Jean-Pierre Triboulet
,
Isabelle van Seuningen
et al.
Article dans une revue
istex
hal-02905828
v1
|
|
Epigenetics, stem cells and epithelial cell fate
Audrey Vincent
,
Isabelle van Seuningen
Article dans une revue
hal-02905791
v1
|
|
Mucins: a new family of epigenetic biomarkers in epithelial cancers
Isabelle van Seuningen
,
Audrey Vincent
Article dans une revue
hal-02905792
v1
|
|
Tumour growth and resistance to gemcitabine of pancreatic cancer cells are decreased by AP-2alpha overexpression.
Nicolas Jonckheere
,
Valérie Fauquette
,
Laurence Stechly
,
Nathalie Saint-Laurent
,
Sébastien Aubert
et al.
Article dans une revue
inserm-00410436
v1
|
|
Qu’est ce que l’épigénétique ? Stratégies d’étude et application au cancer
Isabelle van Seuningen
Article dans une revue
hal-03313794
v1
|
|
The membrane-bound mucins: From cell signalling to transcriptional regulation and expression in epithelial cancers
Nicolas Jonckheere
,
Isabelle van Seuningen
Article dans une revue
hal-02905696
v1
|
|
The regulation of the intestinal mucin MUC2 expression by short chain fatty acids: implications for epithelial protection
Nanda Burger-van Paassen
,
Audrey Vincent
,
Patrycja J Puiman
,
Maria van Der Sluis
,
Janneke Bouma
et al.
Article dans une revue
hal-00479129
v1
|
|
MUC1, a New Hypoxia Inducible Factor Target Gene, Is an Actor in Clear Renal Cell Carcinoma Tumor Progression
Sébastien Aubert
,
Valérie Fauquette
,
Brigitte Hémon
,
Réjane Lepoivre
,
Nicolas Briez
et al.
Article dans une revue
hal-03313790
v1
|
|
IL-6 and IL-8 increase the expression of glycosyltransferases and sulfotransferases involved in the biosynthesis of sialylated and/or sulfated Lewis x} epitopes in the human bronchial mucosa
Sophie Groux-Degroote
,
Marie-Ange Krzewinski-Recchi
,
Aurélie Cazet
,
Audrey Vincent
,
Sylvain Lehoux
et al.
Article dans une revue
hal-00478849
v1
|
|
Resistin-like molecule β regulates intestinal mucous secretion and curtails TNBS-induced colitis in mice
Rim Belharbi Krimi
,
Larissa Kotelevets
,
Laurent Dubuquoy
,
Pascale Plaisancié
,
Francine Walker
et al.
Article dans une revue
hal-03313912
v1
|
|
Combined defects in epithelial and immunoregulatory factors exacerbate the pathogenesis of inflammation: mucin 2-interleukin 10-deficient mice
Maria van Der Sluis
,
Janneke Bouma
,
Audrey Vincent
,
Anna Velcich
,
Kermit Carraway
et al.
Article dans une revue
hal-03313909
v1
|
|
The Membrane-Bound Mucins: How Large O-Glycoproteins Play Key Roles in Epithelial Cancers and Hold Promise as Biological Tools for Gene-Based and Immunotherapies
Nicolas Jonckheere
,
Isabelle Van Seuningen
Article dans une revue
hal-02905788
v1
|
|
Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells
Maria van Der Sluis
,
Audrey Vincent
,
Janneke Bouma
,
Anita Korteland-van Male
,
Johannes B van Goudoever
et al.
Article dans une revue
hal-02905687
v1
|
|
IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines
Raquel Mejías-Luque
,
Sandra Peiró
,
Audrey Vincent
,
Isabelle van Seuningen
,
Carme de Bolós
Article dans une revue
hal-03313911
v1
|
|
Peroxisome proliferator-activated receptor ligand MCC-555 suppresses intestinal polyps in Apc Min/+ mice via extracellular signal-regulated kinase and peroxisome proliferator-activated receptor-dependent pathways
Kiyoshi Yamaguchi
,
Maria Cekanova
,
Michael F Mcentee
,
Joo-Heon Yoon
,
Susan M Fischer
et al.
Article dans une revue
hal-02905848
v1
|
|
IL-6 induces MUC4 expression through gp130/STAT3 pathway in gastric cancer cell lines
Raquel Mejías-Luque
,
Sandra Peiró
,
Audrey Vincent
,
Isabelle van Seuningen
,
Carme de Bolós
Article dans une revue
hal-02905649
v1
|
|
Activation of MUC1 mucin expression by bile acids in human esophageal adenocarcinomatous cells and tissues is mediated by the phosphatidylinositol 3-kinase
Christophe Mariette
,
Guillaume Piessen
,
Emmanuelle Leteurtre
,
Brigitte Hemon
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-02905866
v1
|
|
Epigenetic regulation of the human mucin gene MUC4 in epithelial cancer cell lines involves both DNA methylation and histone modifications mediated by DNA methyltransferases and histone deacetylases
Audrey Vincent
,
Marie-Paule Ducourouble
,
Isabelle Van Seuningen
Article dans une revue
hal-02905794
v1
|
|
Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1α
Guillaume Piessen
,
Nicolas Jonckheere
,
Audrey Vincent
,
Brigitte Hemon
,
Marie-Paule Ducourouble
et al.
Article dans une revue
hal-02905759
v1
|
|
Trefoil factor family 3 peptide promotes human airway epithelial ciliated cell differentiation.
Pierre Lesimple
,
Isabelle van Seuningen
,
Marie-Pierre Buisine
,
Marie-Christine Copin
,
Margitta Hinz
et al.
Article dans une revue
inserm-00143069
v1
|
|
Transcription factor AP-2alpha represses both the mucin MUC4 expression and pancreatic cancer cell proliferation.
Valérie Fauquette
,
Sébastien Aubert
,
Sophie Groux-Degroote
,
Brigitte Hemon
,
Nicole Porchet
et al.
Carcinogenesis / CARCINOGENESIS(LONDON); Carcinogenesis (Oxford), 2007, 28 (11), pp.2305-12. ⟨10.1093/carcin/bgm158⟩
Article dans une revue
hal-00164934
v1
|
|
The Human Mucin MUC4 Is Transcriptionally Regulated by Caudal-related Homeobox, Hepatocyte Nuclear Factors, Forkhead Box A, and GATA Endodermal Transcription Factors in Epithelial Cancer Cells
Nicolas Jonckheere
,
Audrey Vincent
,
Michaël Perrais
,
Marie-Paule Ducourouble
,
Anita Korteland-van Male
et al.
Article dans une revue
hal-02905844
v1
|
|
Metaplasia A Transdifferentiatlon Process that Facilitates Cancer Development: The Model of Gastric Intestinal Metaplasia
Patricia Mesquita
,
Raquel Almeida
,
Nuno Lunet
,
Celso Reis
,
Luis Filipe Santos Silva
et al.
Article dans une revue
hal-03313915
v1
|
|
Muc2-Deficient Mice Spontaneously Develop Colitis, Indicating That MUC2 Is Critical for Colonic Protection
Maria van Der Sluis
,
Barbara A.E. de Koning
,
Adrianus C.J.M. de Bruijn
,
Anna Velcich
,
Jules P.P. Meijerink
et al.
Article dans une revue
hal-03313916
v1
|
|
Regulation of the human mucin MUC4 by taurodeoxycholic and taurochenodeoxycholic bile acids in oesophageal cancer cells is mediated by hepatocyte nuclear factor 1{alpha}
Guillaume Piessen
,
Nicolas Jonckheere
,
Audrey Vincent
,
Brigitte Hémon
,
Marie-Paule Ducourouble
et al.
Article dans une revue
hal-00478670
v1
|
|
Evidence for a functional genetic polymorphism of the human retinoic acid–metabolizing enzyme CYP26A1, an enzyme that may be involved in spina bifida
Emmanuel Rat
,
Ingrid Billaut-Laden
,
Delphine Allorge
,
Jean-Marc Lo-Guidice
,
Marie Tellier
et al.
Birth Defects Research Part A: Clinical and Molecular Teratology, 2006, 76 (6), pp.491-498. ⟨10.1002/bdra.20275⟩
Article dans une revue
istex
hal-02954484
v1
|
|
The microRNA miR-181 targets the homeobox protein Hox-A11 during mammalian myoblast differentiation.
Marjolaine Bauzone
,
Mouloud Souidi
,
Anne-Frédérique Dessein
,
Maxence Wisztorski
,
Audrey Vincent
et al.
Article dans une revue
istex
inserm-04278051
v1
|
|
OCT-1 is over-expressed in intestinal metaplasia and intestinal gastric carcinomas and binds to, but does not transactivate, CDX2 in gastric cells
Raquel Almeida
,
José Almeida
,
Michal Shoshkes
,
Nuno Mendes
,
Patrícia Mesquita
et al.
Article dans une revue
hal-03313917
v1
|
|
Synergistic induction of the MUC4 mucin gene by interferon-γ and retinoic acid in human pancreatic tumour cells involves a reprogramming of signalling pathways
Mahefatiana Andrianifahanana
,
Anshu Agrawal
,
Ajay Singh
,
Nicolas Moniaux
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-03313918
v1
|
|
The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells
Valérie Fauquette
,
Michael Perrais
,
Sylvain Cerulis
,
Nicolas Jonckheere
,
Marie-Paule Ducourouble
et al.
Biochemical Journal, 2005, 386, pp.35 - 45
Article dans une revue
hal-02905757
v1
|
|
The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells
Valérie Fauquette
,
Michael Perrais
,
Sylvain Cerulis
,
Nicolas Jonckheere
,
Marie-Paule Ducourouble
et al.
Article dans une revue
hal-02954487
v1
|
|
Esophageal Carcinoma: Prognostic Differences between Squamous Cell Carcinoma And Adenocarcinoma
Christophe Mariette
,
Laetitia Finzi
,
Guillaume Piessen
,
Isabelle van Seuningen
,
Jean Pierre Triboulet
Article dans une revue
istex
hal-03313920
v1
|
|
A role for human MUC4 mucin gene, the ErbB2 ligand, as a target of TGF-b in pancreatic carcinogenesis
Nicolas Jonckheere
,
Michael Perrais
,
Christophe Mariette
,
Surinder K Batra
,
Jean-Pierre Aubert
et al.
Article dans une revue
hal-02905851
v1
|
|
The murine Muc2 mucin gene is transcriptionally regulated by the zinc-finger GATA-4 transcription factor in intestinal cells
Maria van Der Sluis
,
Monique H M Melis
,
Nicolas Jonckheere
,
Marie-Paule Ducourouble
,
Hans A Bü Ller A
et al.
Article dans une revue
hal-02905675
v1
|
|
Coordinated Expression of MUC2 and CDX-2 in Mucinous Carcinomas of the Lung Can Be Explained by the Role of CDX-2 as Transcriptional Regulator of MUC2
Patrícia Mesquita
,
Raquel Almeida
,
Isabelle van Seuningen
,
Leonor David
Article dans une revue
hal-03313919
v1
|
|
Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway
Christophe Mariette
,
Michaël Perrais
,
Emmanuelle Leteurtre
,
Nicolas Jonckheere
,
Brigitte Hémon
et al.
Article dans une revue
hal-03314562
v1
|
|
Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway
Christophe Mariette
,
Michael Perrais
,
Emmanuelle Leteurtre
,
Nicolas Jonckheere
,
Brigitte Hemon
et al.
Biochemical Journal, 2004, 377, pp.701 - 708
Article dans une revue
hal-02905712
v1
|
|
Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-β/Smad4 signalling pathway is potentiated by Sp1
Nicolas Jonckheere
,
Maria van Der Sluis
,
Amélie Velghe
,
Marie-Pierre Buisine
,
Marjolein Sutmuller
et al.
Article dans une revue
hal-02905751
v1
|
|
Factors Affecting Postoperative Course and Survival After En Bloc Resection for Esophageal Carcinoma
Christophe Mariette
,
Guillaume Taillier
,
Isabelle van Seuningen
,
Jean-Pierre Triboulet
Article dans une revue
istex
hal-03314560
v1
|
|
Transcriptional activation of the murine Muc5ac mucin gene in epithelial cancer cells by TGF-β/Smad4 signalling pathway is potentiated by Sp1
Nicolas Jonckheere
,
Maria van Der Sluis
,
Amélie Velghe
,
Marie-Pierre Buisine
,
Marjolein Sutmuller
et al.
Biochemical Journal, 2004, 377, pp.797 - 808
Article dans une revue
hal-02905715
v1
|
|
Transcriptional regulation of human mucin MUC4 by bile acids in oesophageal cancer cells is promoter-dependent and involves activation of the phosphatidylinositol 3-kinase signalling pathway
Michael Perrais
,
Brigitte Hemon
,
Isabelle van Seuningen
,
Christophe Mariette
,
Michaël Perrais
et al.
Biochemical Journal, 2004, 377, pp.701 - 708
Article dans une revue
hal-02905748
v1
|
|
Human MUC2 Mucin Gene Is Transcriptionally Regulated by Cdx Homeodomain Proteins in Gastrointestinal Carcinoma Cell Lines
Patrícia Mesquita
,
Nicolas Jonckheere
,
Raquel Almeida
,
Marie-Paule Ducourouble
,
Jacinta Serpa
et al.
Article dans une revue
hal-02905842
v1
|
|
Pattern of recurrence following complete resection of esophageal carcinoma and factors predictive of recurrent disease
Christophe Mariette
,
Jean-Michel Balon
,
Guillaune Piessen
,
Sylvain Fabre
,
Isabelle van Seuningen
et al.
Article dans une revue
hal-03316294
v1
|
|
Induction of MUC2 and MUC5AC Mucins by Factors of the Epidermal Growth Factor (EGF) Family Is Mediated by EGF Receptor/Ras/Raf/Extracellular Signal-regulated Kinase Cascade and Sp1
Michael Perrais
,
Pascal Pigny
,
Marie-Christine Copin
,
Jean-Pierre Aubert
,
Isabelle van Seuningen
Article dans une revue
hal-02905840
v1
|
|
Influence of TNFα on the sialylation of mucins produced by a transformed cell line MM-39 derived from human tracheal gland cells
Philippe Delmotte
,
Sophie Degroote
,
Marc Merten
,
Isabelle van Seuningen
,
Annie Bernigaud
et al.
Article dans une revue
istex
hal-03316059
v1
|
|
Influence of TNFα on the sialylation of mucins produced by a transformed cell line MM-39 derived from human tracheal gland cells
Philippe Delmotte
,
Sophie Degroote
,
Marc Merten
,
Isabelle van Seuningen
,
Annie Bernigaud
et al.
Article dans une revue
istex
hal-03314995
v1
|
|
Transcriptional regulation of the 11p15 mucin genes. towards new biological tools in human therapy, in inflammatory diseases and cancer?
Isabelle Van Seuningen
Article dans une revue
hal-03314990
v1
|
|
Influence of culture conditions on the α1,2-fucosyltransferase and MUC gene expression of a transformed cell line MM-39 derived from human tracheal gland cells
Philippe Delmotte
,
Sophie Degroote
,
Marc Merten
,
Annie Bernigaud
,
Isabelle van Seuningen
et al.
Article dans une revue
istex
hal-03316057
v1
|
|
TRANSCRIPTIONAL REGULATION OF THE 11P15 MUCIN GENES. TOWARDS NEW BIOLOGICAL TOOLS IN HUMAN THERAPY, IN INFLAMMATORY DISEASES AND CANCER?
Isabelle van Seuningen
,
Pascal Pigny
,
Michael Perrais
,
Nicole Porchet
,
Jean-Pierre Aubert
Frontiers in Bioscience, 2001, 6
Article dans une revue
hal-02905799
v1
|
|
Influence of culture conditions on the α1,2-fucosyltransferase and MUC gene expression of a transformed cell line MM-39 derived from human tracheal gland cells
Philippe Delmotte
,
Sophie Degroote
,
Marc Merten
,
Annie Bernigaud
,
Isabelle van Seuningen
et al.
Article dans une revue
istex
hal-03314993
v1
|
|
Characterization of Human Mucin Gene MUC4 Promoter
Michael Perrais
,
Pascal Pigny
,
Marie-Paule Ducourouble
,
Daniè Le Petitprez
,
Nicole Porchet
et al.
Article dans une revue
hal-02905838
v1
|
|
Aberrant Expression of Human Mucin Gene MUC5B in Gastric Carcinoma and Cancer Cells
Michael Perrais
,
Pascal Pigny
,
Marie-Pierre Buisine
,
Nicole Porchet
,
Jean-Pierre Aubert
et al.
Article dans une revue
hal-02905839
v1
|
|
Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells
Isabelle Van Seuningen
,
Michaël Perrais
,
Pascal Pigny
,
Nicole Porchet
,
Jean-Pierre Aubert
Article dans une revue
hal-03316039
v1
|
|
Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells
Isabelle van Seuningen
,
Michaël Perrais
,
Pascal Pigny
,
Nicole Porchet
,
Jean-Pierre Aubert
Biochemical Journal, 2000, 348, pp.675 - 686
Article dans une revue
hal-02905746
v1
|
|
Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells
Isabelle Van Seuningen
,
Michaël Perrais
,
Pascal Pigny
,
Nicole Porchet
,
Jean-Pierre Aubert
Article dans une revue
hal-03316061
v1
|
|
Sequence of the 5′-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells
Isabelle Van Seuningen
,
Michaël Perrais
,
Pascal Pigny
,
Nicole Porchet
,
Jean-Pierre Aubert
Article dans une revue
hal-03317695
v1
|
|
Sequence of the 5'-flanking region and promoter activity of the human mucin gene MUC5B in different phenotypes of colon cancer cells
Isabelle van Seuningen
,
Michaël Perrais
,
Pascal Pigny
,
Nicole Porchet
,
Jean-Pierre Aubert
Biochemical Journal, 2000, 348, pp.675 - 686
Article dans une revue
hal-02905708
v1
|
|
Diverse molecular interactions of the hnRNP K protein
Karol Bomsztyk
,
Isabelle van Seuningen
,
Hideaki Suzuki
,
Oleg Denisenko
,
Jerzy Ostrowski
Article dans une revue
hal-03317710
v1
|
|
Genomic organization of the 3' region of the human mucin gene MUC5B.
Jean-Luc Desseyn
,
J P Aubert
,
Isabelle van Seuningen
,
N Porchet
,
A Laine
Article dans une revue
hal-02177047
v1
|
|
Identification of a 42-kDa Nuclear Factor (NF1-MUC5B) from HT-29 MTX Cells That Binds to the 3′ Region of Human Mucin GeneMUC5B
Pascal Pigny
,
Isabelle van Seuningen
,
Jean Luc Desseyn
,
Séverine Nollet
,
Nicole Porchet
et al.
Article dans une revue
istex
hal-03316289
v1
|
|
Zik1, a Transcriptional Repressor That Interacts with the Heterogeneous Nuclear Ribonucleoprotein Particle K Protein
Oleg Denisenko
,
Bruce O'Neill
,
Jerzy Ostrowski
,
Isabelle van Seuningen
,
Karol Bomsztyk
Article dans une revue
hal-03317709
v1
|
|
Human Mucin Genes Assigned to 11p15.5: Identification and Organization of a Cluster of Genes
Pascal Pigny
,
Veronique Guyonnet-Duperat
,
Alexander Hill
,
Wendy Pratt
,
Sylvie Galiegue-Zouitina
et al.
Article dans une revue
istex
hal-03316037
v1
|
|
The K Protein Domain That Recruits the Interleukin 1-responsive K Protein Kinase Lies Adjacent to a Cluster of c-Src and Vav SH3-binding Sites
Isabelle van Seuningen
,
Jerzy Ostrowski
,
Xose Bustelo
,
Paul Sleath
,
Karol Bomsztyk
Article dans une revue
hal-03317707
v1
|
|
Description of an IL-1-Responsive Kinase That Phosphorylates the K Protein. Enhancement of Phosphorylation by Selective DNA and RNA Motifs
Isabelle van Seuningen
,
Jerzy Ostrowski
,
Karol Bomsztyk
Article dans une revue
istex
hal-03317708
v1
|
|
Western blotting of basic proteins after nondenaturing electrophoresis in acid conditions using the PhastSystem
Monique Davril
,
Marie-Paule Ducourouble
,
Isabelle Van-Seuningen
Article dans une revue
istex
hal-03317698
v1
|
|
Involvement of a Signal Transduction Mechanism in ATP-induced Mucin Release from Cultured Airway Goblet Cells
K. Chul Kim
,
Qiao-Xi Zheng
,
Isabelle Van-Seuningen
Article dans une revue
hal-03317696
v1
|
|
A rapid periodic acid-Schiff staining procedure for the detection of glycoproteins using the phastsystem
Isabelle Van-Seuningen
,
Monique Davril
Article dans une revue
istex
hal-03317700
v1
|
|
Strong ionic interactions between mucins and two basic proteins, mucus proteinase inhibitor and lysozyme, in human bronchial secretions
Isabelle Van-Seuningen
,
Nicole Houdret
,
Annette Hayem
,
Monique Davril
Article dans une revue
istex
hal-03317704
v1
|
|
Analysis of the conformation and stability of human bronchial lysozyme by circular dichroism
Isabelle Van-Seuningen
,
Annette Hayem
,
Monique Davril
Article dans une revue
istex
hal-03317702
v1
|
|
Separation of the two domains of human mucus proteinase inhibitor: Inhibitory activity is only located in the car☐y-terminal domain
Isabelle Van-Seuningen
,
Monique Davril
Article dans une revue
istex
hal-03317705
v1
|
|
Electrotransfer of basic proteins from nondenaturing polyacrylamide acid gels to nitrocellulose: Detection of enzymatic and inhibitory activities and retention of protein antigenicity
Isabelle Van-Seuningen
,
Monique Davril
Article dans une revue
istex
hal-03317706
v1
|