JT

Jakub Toczek

Chargé de recherche, Inserm ; UMR Univ. Grenoble Alpes, Inserm U1039 – Radiopharmaceutiques Biocliniques (LRB)
94 %
Libre accès
31
Documents
Affiliation actuelle
  • Radiopharmaceutiques biocliniques (LRB)
Identifiants chercheurs

Publications

Publications

Positron Emission Tomography Imaging of Vessel Wall Matrix Metalloproteinase Activity in Abdominal Aortic Aneurysm

Jakub Toczek , Kiran Gona , Yongjian Liu , Azmi Ahmad , Mean Ghim et al.

Circulation: Cardiovascular Imaging, 2023, 16 (1), ⟨10.1161/CIRCIMAGING.122.014615⟩

Article dans une revue hal-04741598v1

Multimodality Imaging of Aortic Valve Calcification and Function in a Murine Model of Calcific Aortic Valve Disease and Bicuspid Aortic Valve

Azmi Ahmad , Mean Ghim , Jakub Toczek , Afarin Neishabouri , Devi Ojha et al.

Journal of Nuclear Medicine, 2023, 64 (9), pp.1487-1494. ⟨10.2967/jnumed.123.265516⟩

Article dans une revue hal-04741623v1

Homeostatic, Non-Canonical Role of Macrophage Elastase in Vascular Integrity

Mani Salarian , Mean Ghim , Jakub Toczek , Jinah Han , Dar Weiss et al.

Circulation Research, 2023, 132 (4), pp.432-448. ⟨10.1161/CIRCRESAHA.122.322096⟩

Article dans une revue hal-04741617v1

Deletion of matrix metalloproteinase-12 compromises mechanical homeostasis and leads to an aged aortic phenotype in young mice

Bart Spronck , Abhay Ramachandra , Lauren Moriyama , Jakub Toczek , Jinah Han et al.

Journal of Biomechanics, 2022, 141, pp.111179. ⟨10.1016/j.jbiomech.2022.111179⟩

Article dans une revue hal-04741647v1

Differential BMP Signaling Mediates the Interplay Between Genetics and Leaflet Numbers in Aortic Valve Calcification

Jae-Joon Jung , Azmi Ahmad , Saranya Rajendran , Linyan Wei , Jiasheng Zhang et al.

JACC : Basic to Translational Science, 2022, 7 (4), pp.333-345. ⟨10.1016/j.jacbts.2021.12.006⟩

Article dans une revue hal-04741653v1

Considerations on PET/MR imaging of carotid plaque inflammation with 68Ga-Pentixafor

Jakub Toczek , Laurent Riou

Journal of Nuclear Cardiology, 2022, 29 (2), pp.503-505. ⟨10.1007/s12350-020-02354-3⟩

Article dans une revue hal-04741644v1

Targeted Suppression of miRNA-33 Using pHLIP Improves Atherosclerosis Regression

Xinbo Zhang , Noemi Rotllan , Alberto Canfrán-Duque , Jonathan Sun , Jakub Toczek et al.

Circulation Research, 2022, 131 (1), pp.77-90. ⟨10.1161/CIRCRESAHA.121.320296⟩

Article dans une revue hal-04741629v1

Evolution of arterial [18F]-sodium fluoride uptake and calcification

Jakub Toczek

Journal of Nuclear Cardiology, 2021, 28 (5), pp.1946-1948. ⟨10.1007/s12350-019-01969-5⟩

Article dans une revue hal-04741667v1

FDG PET imaging of vascular inflammation in post-traumatic stress disorder: A pilot case–control study

Jakub Toczek , Ansel Hillmer , Jinah Han , Chi Liu , Dana Peters et al.

Journal of Nuclear Cardiology, 2021, 28 (2), pp.688-694. ⟨10.1007/s12350-019-01724-w⟩

Article dans une revue hal-04741657v1

Computed tomography imaging of macrophage phagocytic activity in abdominal aortic aneurysm

Jakub Toczek , Parnaz Boodagh , Nowshin Sanzida , Mean Ghim , Mani Salarian et al.

Theranostics, 2021, 11 (12), pp.5876-5888. ⟨10.7150/thno.55106⟩

Article dans une revue hal-04741663v1

Identifying the leukocyte uptake pattern of inflammation imaging agents: Current limitations and potential impact

Laurent M. Riou , Jakub Toczek , Alexis Broisat , Catherine Ghezzi , Loïc Djaileb

Journal of Nuclear Cardiology, 2020, 28 (4), pp.646-1648. ⟨10.1007/s12350-019-01979-3⟩

Article dans une revue inserm-02440546v1

Accuracy of arterial [18F]-Fluorodeoxyglucose uptake quantification: A kinetic modeling study

Jakub Toczek , Jing Wu , Ansel Hillmer , Jinah Han , Irina Esterlis et al.

Journal of Nuclear Cardiology, 2020, 27 (5), pp.1578-1581. ⟨10.1007/s12350-020-02055-x⟩

Article dans une revue hal-04741677v1
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Hydroxamate-Based Selective Macrophage Elastase (MMP-12) Inhibitors and Radiotracers for Molecular Imaging

Kiran Gona , Jakub Toczek , Yunpeng Ye , Nowshin Sanzida , Arvene Golbazi et al.

Journal of Medicinal Chemistry, 2020, 63 (23), pp.15037-15049. ⟨10.1021/acs.jmedchem.0c01514⟩

Article dans une revue hal-03320529v1

Genetic deficiency or pharmacological inhibition of miR-33 protects from kidney fibrosis

Nathan Price , Verónica Miguel , Wen Ding , Abhishek Singh , Shipra Malik et al.

JCI Insight, 2019, 4 (22), pp.9743-9752. ⟨10.1172/jci.insight.131102⟩

Article dans une revue hal-04741696v1

Novel Matrix Metalloproteinase 12 Selective Radiotracers for Vascular Molecular Imaging

Jakub Toczek , Thomas Bordenave , Kiran Gona , Hye-Yeong Kim , Fabrice Beau et al.

Journal of Medicinal Chemistry, 2019, 62 (21), pp.9743-9752. ⟨10.1021/acs.jmedchem.9b01186⟩

Article dans une revue hal-04467935v1

Novel Arginine-containing Macrocyclic MMP Inhibitors: Synthesis, 99mTc-labeling, and Evaluation

Yunpeng Ye , Jakub Toczek , Kiran Gona , Hye-Yeong Kim , Jinah Han et al.

Scientific Reports, 2018, 8 (1), pp.11647. ⟨10.1038/s41598-018-29941-2⟩

Article dans une revue hal-04741713v1

Matrix Metalloproteinase–Targeted Imaging of Lung Inflammation and Remodeling

Reza Golestani , Mahmoud Razavian , Yunpeng Ye , Jiasheng Zhang , Jae-Joon Jung et al.

Journal of Nuclear Medicine, 2017, 58 (1), pp.138-143. ⟨10.2967/jnumed.116.176198⟩

Article dans une revue hal-04741737v1

Characterization of Macrophage Polarization States Using Combined Measurement of 2-Deoxyglucose and Glutamine Accumulation

Sina Tavakoli , Kevin Downs , John Short , Huynh Nga Nguyen , Yanlai Lai et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2017, 37 (10), pp.1840-1848. ⟨10.1161/ATVBAHA.117.308848⟩

Article dans une revue hal-04741727v1

Preclinical Evaluation of RYM1, a Matrix Metalloproteinase–Targeted Tracer for Imaging Aneurysm

Jakub Toczek , Yunpeng Ye , Kiran Gona , Hye-Yeong Kim , Jinah Han et al.

Journal of Nuclear Medicine, 2017, 58 (8), pp.1318-1323. ⟨10.2967/jnumed.116.188656⟩

Article dans une revue hal-04741721v1

A New Tracer for Imaging Atherosclerosis

Jakub Toczek , Mehran Sadeghi

Circulation: Cardiovascular Imaging, 2016, 9 (5), ⟨10.1161/CIRCIMAGING.116.004889⟩

Article dans une revue hal-04741747v1

Optical imaging of MMP-12 active form in inflammation and aneurysm

Mahmoud Razavian , Thomas Bordenave , Dimitris Georgiadis , Fabrice Beau , Jiasheng Zhang et al.

Scientific Reports, 2016, 6 (1), pp.38345. ⟨10.1038/srep38345⟩

Article dans une revue hal-04741787v1

Matrix metalloproteinase inhibitor, doxycycline and progression of calcific aortic valve disease in hyperlipidemic mice

Jae-Joon Jung , Mahmoud Razavian , Hye-Yeong Kim , Yunpeng Ye , Reza Golestani et al.

Scientific Reports, 2016, 6 (1), pp.32659. ⟨10.1038/srep32659⟩

Article dans une revue hal-04741791v1

Molecular imaging concepts

Jakub Toczek , Mehran Sadeghi

Journal of Nuclear Cardiology, 2016, 23 (2), pp.271-273. ⟨10.1007/s12350-016-0403-9⟩

Article dans une revue hal-04741745v1

Novel Molecular Imaging Approaches to Abdominal Aortic Aneurysm Risk Stratification

Jakub Toczek , Judith Meadows , Mehran Sadeghi

Circulation: Cardiovascular Imaging, 2016, 9 (1), ⟨10.1161/CIRCIMAGING.115.003023⟩

Article dans une revue (article de synthèse) hal-04741753v1
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Periaortic Brown Adipose Tissue as a Major Determinant of [18F]-Fluorodeoxyglucose Vascular Uptake in Atherosclerosis-Prone, ApoE−/− Mice

Jakub Toczek , Alexis Broisat , Pascale Perret , Marie-Dominique Desruet , Daniel Fagret et al.

PLoS ONE, 2014, 9 (7), pp.e99441. ⟨10.1371/journal.pone.0099441⟩

Article dans une revue hal-04660958v1
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99mTc-cAbVCAM1-5 Imaging Is a Sensitive and Reproducible Tool for the Detection of Inflamed Atherosclerotic Lesions in Mice

Alexis Broisat , Jakub Toczek , Laurent Dumas , Mitra Ahmadi , Sandrine Bacot et al.

European Journal of Nuclear Medicine, 2014, 55 (10), pp.1678-1684. ⟨10.2967/jnumed.114.143792⟩

Article dans une revue inserm-01077899v1

Nanobody-coupled microbubbles as novel molecular tracer

Sophie Hernot , Sunil Unnikrishnan , Zhongmin Du , Talent Shevchenko , Bernard Cosyns et al.

Journal of Controlled Release, 2012, 158 (2), pp.346-353. ⟨10.1016/j.jconrel.2011.12.007⟩

Article dans une revue hal-04742002v1
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Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions.

Alexis Broisat , Sophie Hernot , Jakub Toczek , Jens de Vos , Laurent M. Riou et al.

Circulation Research, 2012, 110 (7), pp.927-37. ⟨10.1161/CIRCRESAHA.112.265140⟩

Article dans une revue inserm-00831749v1

Elucidating atherosclerotic vulnerable plaque rupture by modeling cross substitution of ApoE-/- mouse and human plaque components stiffnesses.

Jacques Ohayon , Nicolas Mesnier , Alexis Broisat , Jakub Toczek , Laurent Riou et al.

Biomechanics and Modeling in Mechanobiology, 2012, 11 (6), pp.801-13. ⟨10.1007/s10237-011-0353-8⟩

Article dans une revue istex hal-00846364v1

Assessing low levels of mechanical stress in aortic atherosclerotic lesions from apolipoprotein E-/- mice--brief report.

Alexis Broisat , Jakub Toczek , Nicolas Mesnier , Philippe Tracqui , Catherine Ghezzi et al.

Arteriosclerosis, Thrombosis, and Vascular Biology, 2011, 31 (5), pp.1007-10. ⟨10.1161/ATVBAHA.111.225227⟩

Article dans une revue hal-00846368v1