
Jean-Marie HEYDEL
- Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA)
Présentation
Jean-Marie Heydel currently works at the Centre des Sciences du Goût et de l’Alimentation (CSGA), University of Burgundy France. He is Professor in Biochemistry and molecular Biology at the University for Health Sciences in Dijon France. He has been continuously interested in Xenobiotic metabolism. Since 2005, he has led a working group investigating the function of XMEs in olfaction and taste. In the frame of transversal collaborations, he showed that XMEs are involved in the clearance of chemosensory molecules from the receptors environment and/or in the synthesis of chemosensory active metabolites both having significant consequences on perception (models: rodents, rabbit, drosophila, Human). His research interests currently focuse on xenobiotic metabolism at the brain interface, olfaction, peripheral physiology and biochemistry of smell and taste, animal and human volatilome.
Publications
Publications
Role of oral bacterial glycosidases in human flavor perceptionThe International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence
hal-04771642
v1
|
|
Purification and functional characterization of three human salivary proline-rich proteins involved in astringencyThe International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence
hal-04771592
v1
|
|
Characterization of the glutathione transferases involved in the olfactory metabolism of the mammary pheromoneThe International Symposium on Olfaction and Taste (ISOT), Jun 2024, Reykjavík, Iceland
Poster de conférence
hal-04771537
v1
|
|
|
Impact of aldehyde dehydrogenases and aldo-keto reductases on human olfactory peri-receptor events45. annual meeting - association for chemoreception sciences (AChemS), Apr 2023, Bonita Springs, Florida, United States.
Poster de conférence
hal-04095217
v1
|
[Thu-P1-027] Pheromone-induced odour learning and outstanding detection abilities in the newborn rabbit32. international congress of the european-chemoreception-research-organization (ECRO), Aug 2022, Berlin, Germany
Poster de conférence
hal-03810680
v1
|
|
The NAOMI (Nasal Odorant Metabolites) consortium: an international, multidisciplinary consortium investigating how metabolites resulting from nasal enzymatic odorant metabolism can shape odor perception16. Weurman Flavour Research Symposium, May 2021, Dijon, France.
Poster de conférence
hal-03253429
v1
|
|
Characterization of rat glutathione transferases in olfactory mucus and epithelium29. Annual Meeting of the European-Chemoreception-Research-Organization, Sep 2019, Trieste, Italy. pp.P24, ECRO 2019
Poster de conférence
hal-02885473
v1
|
|
Odorants' metabolism in Human: a critical role in odor perception revealed40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. , Chemical Senses, 43 (7), 1 p., 2018
Poster de conférence
hal-02736238
v1
|
|
Odorant metabolism in olfactory mucus: characterization and impact on olfactory perception40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. Oxford University Press, Chemical Senses, 43 (7), 1 p., 2018
Poster de conférence
hal-02735550
v1
|
|
P45 - Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in foodThe 26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2016, Dijon, France
Poster de conférence
hal-02917669
v1
|
|
Structural and enzymatic characterization of a Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in food17. international symposium on Olfaction and taste (ISOT), Jun 2016, Yokohama, Japan. Oxford University Press, Chemical Senses, 41 (9), 1 p., 2016, Chemical Senses
Poster de conférence
hal-01579982
v1
|
|
Inhibition of the mammary pheromone catabolism by a second odorant present in the same mixture24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France. Oxford University Press, Chemical Senses, 40 (3), pp.2, 2015, Proceedings of the 24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO)
Poster de conférence
hal-02743312
v1
|
|
|
Odorant biotransformation by human gluthatione-S-transferases24. Annual Meeting of the European Chemoreception Research Organization (ECRO 2014), Sep 2014, Dijon, France. Oxford University Press, Chemical Senses, 40 (3), pp.2, 2015, Abstracts from the 24th Annual Meeting of the European Chemoreception Research Organization (ECRO 2014). ⟨10.1093/chemse/bju073⟩
Poster de conférence
hal-02744377
v1
|
Rôle des enzymes du métabolisme des xénobiotiques dans la perception de la caféine chez la drosophile16. Colloque de Biologie de l’Insecte, Oct 2010, Lyon, France. 1 p., 2010
Poster de conférence
hal-02822422
v1
|
|
Olfactory xenobiotic metabolizing enzymes have an impact on the stimulating properties of some odorants32. Annual meeting (AChemS), Apr 2010, Saint Petersburg, Florida, United States. 1 p., 2010
Poster de conférence
hal-02818714
v1
|
|
Endocrine disruptors found in food modulate estradiol cellular metabolism2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France
Poster de conférence
hal-03757959
v1
|
|
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional preventionEuropean Partnership Meetings: Taste, Nutrition, Health, Jun 2007, Dijon, France
Poster de conférence
hal-03838370
v1
|
|
Major sulfation pathway for resveratrol metabolism in human hepatic derived cells and resveratrol –dependent inducibility of conjugating enzymes. Perspective in nutritional prevention2. congrès international Santé et Nutrition VITAGORA, Mar 2007, Dijon, France
Poster de conférence
hal-03838598
v1
|
Odorant metabolizing enzymes in the peripheral olfactory processElisabeth Guichard; Christian Salles. Flavor: From Food to Behaviors, Wellbeing and Health, Second edition, Chapter 5, , pp.127-147, 2023, 978-0-323-89903-1. ⟨10.1016/B978-0-323-89903-1.00014-1⟩
Chapitre d'ouvrage
hal-04002413
v1
|
|
Odorant metabolizing enzymes in the peripheral olfactory processFlavour: From food to perception, John Wiley & Sons, Inc., 424 p., 2017, 978-1-118-92941-4
Chapitre d'ouvrage
hal-01585726
v1
|
|
Système olfacto-gustatif et toxicologieOdorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, 2012, Synthèses (Quae), ISBN-13 : 978-2-7592-1770-0
Chapitre d'ouvrage
hal-02804272
v1
|
|
Périréception et protéines porteusesSalesse, Roland ; Gervais, Rémi. Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, pp.61-73, 2012, Collection Synthèses, 978-2-7592-1770-0
Chapitre d'ouvrage
hal-00787942
v1
|
|
Système olfacto-gustatif et toxicologieSalesse, Roland ; Gervais, Rémi. Odorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, pp.465-472, 2012, Collection Synthèses, 978-2-7592-1770-0
Chapitre d'ouvrage
hal-00787914
v1
|
|
Périréception et protéines porteusesOdorat et goût. De la neurobiologie des sens chimiques aux applications, Editions Quae, 2012, Synthèses (Quae), 978-2-7592-1770-0 978-2-7592-1770-0
Chapitre d'ouvrage
hal-02809036
v1
|
Flavour from the molecules to the behaviourFood Science Meeting, May 2022, Valence, Spain
Communication dans un congrès
hal-03828980
v1
|
|
Molecules of the flavorIATA Conference, Instituto de Agroquímica y Tecnología de Alimentos, Jun 2022, Valence, Spain
Communication dans un congrès
hal-03827290
v1
|
|
Role of human metabolizing enzymes in food perceptionFORTHEM Food Science Lab Workshop, Mar 2022, Palermo, Italy
Communication dans un congrès
hal-03611500
v1
|
|
Function of nasal odorant metabolism in vertebrate olfactionConférence ISIPCA, Jan 2021, Paris, France
Communication dans un congrès
hal-03179876
v1
|
|
How odorant metabolizing enzymes shape odor perception?The International Symposium on Olfaction and Taste (ISOT), Aug 2020, virtual congress, United States
Communication dans un congrès
hal-03053514
v1
|
|
Implication des enzymes dans la perception chimio-sensorielle : une piste dans les troubles olfacto-gustatifs induits par des xénobiotiques ?Journées Nacre, Dec 2019, Paris, France
Communication dans un congrès
hal-02944510
v1
|
|
Function of nasal odorant metabolism in mammalian olfaction40. annual meeting - association for chemoreception sciences (AChemS), Apr 2018, Bonita Springs, Florida, United States. 2 p
Communication dans un congrès
hal-02735549
v1
|
|
Les systèmes de détoxification dans le signal olfactifColloque de l'ARET (association pour la recherche en toxicologie), May 2018, Dijon, France
Communication dans un congrès
hal-02785733
v1
|
|
Drosophila melanogaster glutathione transferase overexpressed in the sensory organs after exposure to bitter molecules in foodThe 26. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Marika Kapsimali, Sep 2016, Dijon, France. pp.E45-E46
Communication dans un congrès
hal-02912249
v1
|
|
|
Aroma volatile odorous metabolites at olfactory mucosa level evidenced by in vitro and in vitro PTS-MS studies26. annual meeting of the european-chemoreception-research-organization (ECRO), European Chemoreception Research Organization (ECRO). INT., Sep 2016, Dijon, France. ⟨10.1093/chemse/bjw120⟩
Communication dans un congrès
hal-01595518
v1
|
New insights in vertebrate 'biotransfolfactionThe 26. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2016, Dijon, France. pp.E-18-E19
Communication dans un congrès
hal-02912358
v1
|
|
New insights in vertebrate << biotransfolfaction >>26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2016, Athènes, Greece
Communication dans un congrès
hal-01565918
v1
|
|
Odorant-odorant metabolic competitions: ex vivo inhibition of the mammary pheromone catabolism26th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2016, Athènes, Greece. pp.E50-E51
Communication dans un congrès
hal-01565748
v1
|
|
Aroma volatile metabolites at olfactory mucosa level evidenced by in vitro PTR-Tof-MS studies7. International conference on proton transfer reaction mass spectrometry and its applications, Armin Hansel and Jürgen Dunkl, Feb 2016, Obergurgl, Austria
Communication dans un congrès
hal-01515660
v1
|
|
|
Interactions of human nasal glutathione transferases with odorants.25th Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), European Chemorecept Res Org, Sep 2015, Istanbul, Turkey. pp.422-422, ⟨10.1093/chemse/bjw019⟩
Communication dans un congrès
hal-01398373
v1
|
Real time monitoring of the metabolic capacity of ex-vivo rat olfactory mucosa by on-line PTR-MS11. Wartburg symposium on flavor chemistry & biology, Jun 2016, Eisenach, Germany
Communication dans un congrès
hal-01581528
v1
|
|
Role of CYP6d5 in the metabolism and the sensory perception of caffeine in <em>Drosophila melanogaster</em>24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), Sep 2014, Dijon, France
Communication dans un congrès
hal-02742181
v1
|
|
Real time monitoring of the metabolic capacity of ex-vivo rat olfactory mucosa by on-line PTR-MSCongrès français de Spectrométrie de Masse et d'Analyse Protéomique (SMAP 2015), Sep 2015, Ajaccio, Corse, France. 1 p
Communication dans un congrès
hal-01580721
v1
|
|
Caffeine metabolism in <em>Drosophila melanogaster</em>24. Annual Meeting of the European-Chemoreception-Research-Organization (ECRO), 2015, Oxford, United Kingdom
Communication dans un congrès
hal-02741361
v1
|
|
Métabolisme périphérique des odorants : arrêt ou modulation du signal olfactif ?1. réunion du GDR (Groupe De Réflexion) Odorant Odeur Olfaction, Centre National de la Recherche Scientifique (CNRS). FRA., Oct 2015, Dijon, France
Communication dans un congrès
hal-01594081
v1
|
|
Oxidative stress and xenobiotic detoxification enzymes in rat astrocytes: Correlations with brain aging11th International Symposium on the Neurobiology and Neuroendocrinology of Aging, Jul 2012, Bregenz, Austria. pp.688-688, ⟨10.1016/j.exger.2013.05.021⟩
Communication dans un congrès
istex
hal-00879048
v1
|
|
Role of xenobiotic metabolizing enzymes in the perception of caffeine in Drosophila melanogaster16th International Symposium on Olfaction and Taste (ISOT), Jun 2012, Stockholm, Sweden
Communication dans un congrès
hal-00746002
v1
|
|
Role of CYTOCHROME p450 in the perception of caffeine in Drosophila melanogaster25th French Drosophila Conference, Oct 2011, Lyon, France
Communication dans un congrès
hal-00745782
v1
|
|
Role of CYTOCHROME p450 in the perception of caffeine in Drosophila melanogasterThe 21st Congress of the Eropean Chemoreception Research Organisation (ECRO), Sep 2011, Manchester, United Kingdom. 1 p
Communication dans un congrès
hal-00745790
v1
|
|
Olfactory xenobiotic metabolizing enzymes have an impact on the stimulating properties of some odorantsThe 32nd Annual Meeting - Association for Chemoreception Sciences (AChemS), Apr 2010, St Pete Beach, Florida, United States
Communication dans un congrès
hal-00816544
v1
|
|
Activity and expression of drug metabolizing enzymes in olfactory mucosa of rats treated by hepatic inducersList of Abstracts from the 18. Congress of European Chemoreception Research Organization, ECRO–2008, Sep 2008, Ljubljana, Slovenia
Communication dans un congrès
hal-02822861
v1
|
|
Glutathione conjugation of the rabbit mammary pheromone 2-methylbut-2-enal18. Congress of European Chemoreception Research Organization, ECRO–2008, Sep 2008, Portoroz, Slovenia
Communication dans un congrès
hal-02819467
v1
|
|
Biotransformation of odorants modifies the olfactory signal31. Annual meeting - Association for chemoreception sciences (Achems), Apr 2009, Sarasota, Floride, United States. 1 p
Communication dans un congrès
hal-02754927
v1
|
Is there a role for salivary detoxification enzymes in taste perception?2021, Proceedings of the 16. Weurman flavour research symposium, ⟨10.5281/zenodo.5575005⟩
Proceedings/Recueil des communications
hal-03686461
v1
|
|
Characterization of rat glutathione transferases in olfactory mucus and epithelium/, Chemical Senses, 45 (2), Oxford University Press, pp.150-150, 2020
Proceedings/Recueil des communications
hal-02943942
v1
|
Odorant metabolism in olfactory mucus: characterization and impact on olfactory perception.2018
Autre publication scientifique
hal-02386821
v1
|
ARET : colloque 2018 au CSGA Dijon. 28 et 29 mai 2018 - CSGA, 9E boulevard Jeanne d'Arc, Dijon2018
Article de blog scientifique
hal-02785817
v1
|