jean-philippe herbeuval

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Publications

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Macrophages: Key Cellular Players in HIV Infection and Pathogenesis

Marie Woottum , Sen Yan , Sophie Sayettat , Séverine Grinberg , Dominique Cathelin et al.
Viruses, 2024, 16, ⟨10.3390/v16020288⟩
Article dans une revue hal-04727692 v1
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Macrophages: Key Cellular Players in HIV Infection and Pathogenesis

Marie Woottum , Sen Yan , Sophie Sayettat , Séverine Grinberg , Dominique Cathelin et al.
Viruses, 2024, 16 (2), pp.288. ⟨10.3390/v16020288⟩
Article dans une revue hal-05038279 v1

Are blockers of gp120/CD4 interaction effective inhibitors of HIV-1 immunopathogenesis?

Jean-Philippe Herbeuval , Gene Shearer
Aids Reviews, 2023, 8 (1), pp.3-8
Article dans une revue hal-04198886 v1
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Editorial: Type 1 interferon in pathologies, autoimmune diseases, and chronic viral infections: understanding the fascinating biologic role of type 1 interferons

Jean-Philippe Herbeuval
Frontiers in Immunology, 2023, 14, pp.1239086. ⟨10.3389/fimmu.2023.1239086⟩
Article dans une revue hal-04198755 v1
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Successful treatment of JAK1 associated inflammatory disease

Antoine Fayand , Véronique Hentgen , Céline Posseme , Carole Lacout , Capucine Picard et al.
Journal of Allergy and Clinical Immunology, 2023, 152 (4), pp.972-983. ⟨10.1016/j.jaci.2023.06.004⟩
Article dans une revue hal-04137977 v1
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Pathogenic variants in the NLRP3 LRR domain at position 861 are responsible for a boost-dependent atypical CAPS phenotype.

Antoine Fayand , Margaux Cescato , Laurent Le Corre , Alexandre Terré , Margaux Wacheux et al.
Journal of Allergy and Clinical Immunology, 2023, 152 (5), pp.1303-1311.e1. ⟨10.1016/j.jaci.2023.07.006⟩
Article dans une revue hal-04182567 v1
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Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis

Nassima Bekaddour , Nikaïa Smith , Benoit Beitz , Alba Llibre , Tom Dott et al.
Frontiers in Immunology, 2023, 14, pp.1178172. ⟨10.3389/fimmu.2023.1178172⟩
Article dans une revue (article de synthèse) pasteur-04245544 v2
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Spermine and spermidine bind CXCR4 and inhibit CXCR4- but not CCR5-tropic HIV-1 infection

Mirja Harms , Nikaïa Smith , Mingyu Han , Rüdiger Groß , Pascal von Maltitz et al.
Science Advances , 2023, 9 (27), pp.eadf8251. ⟨10.1126/sciadv.adf8251⟩
Article dans une revue hal-04198762 v1

Correction to: Onset and Relapse of Juvenile Dermatomyositis Following Asymptomatic SARS-CoV-2 Infection

Mathieu Paul Rodero , Stéphane Pelleau , Anne Welfringer-Morin , Darragh Duffy , Isabelle Melki et al.
Journal of Clinical Immunology, 2022, 42 (1), pp.28-28. ⟨10.1007/s10875-021-01135-y⟩
Article dans une revue hal-04198795 v1
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CXCR4 as a novel target in immunology: moving away from typical antagonists

Birgit Caspar , Pietro Cocchiara , Armelle Melet , Kristof van Emelen , Annegret van der Aa et al.
Future Drug Discovery, 2022, 4 (2), pp.FDD77. ⟨10.4155/fdd-2022-0007⟩
Article dans une revue (article de synthèse) hal-04198790 v1
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JAK inhibitors are effective in a subset of patients with juvenile dermatomyositis: a monocentric retrospective study

Tom Le Voyer , Cyril Gitiaux , François-Jérôme Authier , Christine Bodemer , Isabelle Melki et al.
Rheumatology, 2021, pp.keab116. ⟨10.1093/rheumatology/keab116⟩
Article dans une revue pasteur-03236464 v1

Differential levels of IFNα subtypes in autoimmunity and viral infection

Jean-Philippe Herbeuval , Claude Lambert , Odile Sabido , Michèle Cottier , Pierre Fournel et al.
Cytokine, 2021, 144 (8), pp.155533. ⟨10.1093/jnci/95.8.611⟩
Article dans une revue hal-04198809 v1
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Differential levels of IFNα subtypes in autoimmunity and viral infection

Vincent Bondet , Mathieu P. Rodero , Céline Posseme , Pierre Bost , Jérémie Decalf et al.
Cytokine, 2021, pp.155533. ⟨10.1016/j.cyto.2021.155533⟩
Article dans une revue pasteur-03236276 v1
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Isolation of Tonsillar Mononuclear Cells to Study Ex Vivo Innate Immune Responses in a Human Mucosal Lymphoid Tissue

Nikaïa Smith , Nassima Bekaddour , Nicolas Leboulanger , Yolande Richard , Jean-Philippe Herbeuval
Journal of visualized experiments : JoVE, 2020, 160, ⟨10.3791/60914⟩
Article dans une revue hal-03051482 v1
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Beyond Anti-viral Effects of Chloroquine/Hydroxychloroquine

Vincent Gies , Nassima Bekaddour , Yannick Dieudonné , Aurélien Guffroy , Quentin Frenger et al.
Frontiers in Immunology, 2020, 11, ⟨10.3389/FIMMU.2020.01409⟩
Article dans une revue hal-02996379 v1
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Cerpegin-derived furo[3,4-c]pyridine-3,4(1H,5H)-diones enhance cellular response to interferons by de novo pyrimidine biosynthesis inhibition

Simon Hayek , Nicolas Pietrancosta , Anna Hovhannisyan , Rodolphe Alves de Sousa , Nassima Bekaddour et al.
European Journal of Medicinal Chemistry, 2020, 186, pp.111855. ⟨10.1016/j.ejmech.2019.111855⟩
Article dans une revue hal-02372490 v1
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Inhibition of IFNα secretion in cells from patients with juvenile dermatomyositis under TBK1 inhibitor treatment revealed by single-molecular assay technology

Cyril Gitiaux , Vincent Bondet , Nassima Bekaddour , Patrick Nusbaum , Arnaud Hubas et al.
Rheumatology, 2020, pp.kez508. ⟨10.1093/rheumatology/kez508⟩
Article dans une revue pasteur-02376263 v1
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TRIM8 is required for virus-induced IFN response in human plasmacytoid dendritic cells

Ghizlane Maarifi , Nikaïa Smith , Sarah Maillet , Olivier Moncorgé , Célia Chamontin et al.
Science Advances , 2019, 5 (11), pp.eaax3511. ⟨10.1126/sciadv.aax3511⟩
Article dans une revue hal-02404478 v1
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Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement—A new target for lupus treatment

Nikaïa Smith , Mathieu Rodéro , Nassima Bekaddour , Vincent Bondet , Yasser Ruiz-Blanco et al.
Science Advances , 2019, 5 (7), pp.eaav9019. ⟨10.1126/sciadv.aav9019⟩
Article dans une revue pasteur-02282952 v1

Hitting the right spot on CXCR4

Jessica Mchugh , Jean-Philippe Herbeuval , Nikaia Smith
Nature Reviews Rheumatology, 2019, 15 (9), pp.514-514. ⟨10.1038/s41584-019-0287-6⟩
Article dans une revue hal-02372533 v1

Semen inhibits Zika virus infection of cells and tissues from the anogenital region

Janis Müller , Mirja Harms , Franziska Krüger , Rüdiger Groß , Simone Joas et al.
Nature Communications, 2018, 9 (1), pp.2207. ⟨10.1038/s41467-018-04442-y⟩
Article dans une revue hal-04249967 v1

Chemical pollution and innate antiviral immunity: Dangerous Liaisons ?

Simon Hayek , Nicolas Pietrancosta , Rodolphe Alves De Sousa , Robert Barouki , Jean-Philippe Herbeuval et al.
Virologie, 2018, 22 (1), pp.1-13. ⟨10.1684/vir.2018.0717⟩
Article dans une revue hal-02351261 v1
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Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay

Simon Hayek , Nassima Bekaddour , Laurie Besson , Rodolphe Alves de Sousa , Nicolas Pietrancosta et al.
Slas Discovery, 2018, 24 (1), pp.25-37. ⟨10.1177/2472555218797078⟩
Article dans une revue hal-02324386 v1
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Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons

Laura Sinigaglia , Ségolène Gracias , Elodie Décembre , Matthieu Fritz , Daniela Bruni et al.
Scientific Reports, 2018, 8 (1), ⟨10.1038/s41598-018-29235-7⟩
Article dans une revue hal-02327450 v1

Pollution chimique et immunité innée antivirale : des liaisons dangereuses ?

Simon Hayek , Nicolas Pietrancosta , Rodolphe Alves De Sousa , Robert Barouki , Jean-Philippe Herbeuval et al.
Virologie, 2018, 22 (1), pp.27-40. ⟨10.1684/vir.2018.0718⟩
Article dans une revue hal-03652525 v1
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Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

Anas Allam , Laure Maigre , Julia Vergalli , Estelle Dumont , Bertrand Cinquin et al.
Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Article dans une revue hal-01831783 v1

Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria

Anas Allam , Laure Maigre , Julia Vergalli , Estelle Dumont , Bertrand Cinquin et al.
Scientific Reports, 2017, 7 (1), pp.986. ⟨10.1038/s41598-017-00945-8⟩
Article dans une revue hal-03652530 v1
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Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement

Nikaïa Smith , Nicolas Pietrancosta , Sophia Davidson , Jacques Dutrieux , Lise Chauveau et al.
Nature Communications, 2017, 8, pp.14253. ⟨10.1038/ncomms14253⟩
Article dans une revue hal-02075366 v1

CXCR4, le nouveau régulateur de l’immunité innée ?

Nikaïa Smith , Nicolas Pietrancosta , Jean-Philippe Herbeuval
Médecine/Sciences, 2017, 33 (8-9), pp.711-713. ⟨10.1051/medsci/20173308008⟩
Article dans une revue hal-02351272 v1
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Identification of a small molecule that primes the type I interferon response to cytosolic DNA

Samira Khiar , Marianne Lucas-Hourani , Sebastien Nisole , Nikaia Smith , Olivier Helynck et al.
Scientific Reports, 2017, 7 (1), pp.2561. ⟨10.1038/s41598-017-02776-z⟩
Article dans une revue pasteur-01570224 v1

Plasmacytoid dendritic cells and myeloid cells differently contribute to BAFF over-expression during primary HIV infection

Gwenoline Borhis , Chantal Burelout , Nada Chaoul , Nikaïa Smith , Cecile Goujard et al.
AIDS. Official journal of the international AIDS Society, 2016, pp.1. ⟨10.1097/QAD.0000000000000965⟩
Article dans une revue hal-02346130 v1
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An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept

Nikaïa Smith , Pierre-Olivier Vidalain , Sébastien Nisole , Jean-Philippe Herbeuval
Scientific Reports, 2016, 6 (1), ⟨10.1038/srep29891⟩
Article dans une revue hal-02438269 v1
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Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women.

Morgane Griesbeck , Susanne Ziegler , Sophie Laffont , Nikaïa Smith , Lise Chauveau et al.
Journal of Immunology, 2015, 195 (11), pp.5327-36. ⟨10.4049/jimmunol.1501684⟩
Article dans une revue pasteur-01372393 v1

Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers

Lucie Barblu , Nikaïa Smith , Stéphanie Durand , Daniel Scott-Algara , Faroudy Boufassa et al.
Clinical Immunology, 2014, 155 (1), pp.17-26. ⟨10.1016/j.clim.2014.07.010⟩
Article dans une revue hal-02322630 v1

Rasv12 induces survivin/auroraB pathway conferring tumor cell apoptosis resistance

Réda Hadj-Slimane , Perayot Pamonsinlapatham , Jean-Philippe Herbeuval , Christiane Garbay , Yves Lepelletier et al.
Cellular Signalling, 2010, 22 (8), pp.1214-1221. ⟨10.1016/j.cellsig.2010.03.013⟩
Article dans une revue istex hal-00473108 v1

Free HTLV-1 induces TLR7-dependent innate immune response and TRAIL relocalization in killer plasmacytoid dendritic cells

Renaud Colisson , Lucie Barblu , Christophe Gras , Françoise Raynaud , Reda Hadj-Slimane et al.
Blood, 2010, 115 (11), pp.2177-2185. ⟨10.1182/blood-2009-06-224741⟩
Article dans une revue hal-04249994 v1

RasV12 induces Survivin/AuroraB pathway conferring tumor cell apoptosis resistance

Réda Hadj-Slimane , Perayot Pamonsinlapatham , Jean-Philippe Herbeuval , Christiane Garbay , Yves Lepelletier et al.
Cellular Signalling, 2010, 22 (8), pp.1214-1221. ⟨10.1016/j.cellsig.2010.03.013⟩
Article dans une revue istex hal-04250005 v1

HAART reduces death ligand but not death receptors in lymphoid tissue of HIV-infected patients and simian immunodeficiency virus-infected macaques

Jean-Philippe Herbeuval , Jakob Nilsson , Adriano Boasso , Andrew Hardy , Monica Vaccari et al.
AIDS. Official journal of the international AIDS Society, 2009, 23 (1), pp.35-40. ⟨10.1097/QAD.0b013e32831cb907⟩
Article dans une revue hal-04204741 v1

HIV turns plasmacytoid dendritic cells (pDC) into TRAIL-expressing killer pDC and down-regulates HIV coreceptors by Toll-like receptor 7-induced IFN-α

Andrew Hardy , David Graham , Gene Shearer , Jean-Philippe Herbeuval
Proceedings of the National Academy of Sciences of the United States of America, 2007, 104 (44), pp.17453-17458. ⟨10.1073/pnas.0707244104⟩
Article dans une revue hal-04204737 v1

HIV-1 immunopathogenesis: How good interferon turns bad

Jean-Philippe Herbeuval , Gene Shearer
Clinical Immunology, 2007, 123 (2), pp.121-128. ⟨10.1016/j.clim.2006.09.016⟩
Article dans une revue hal-04204725 v1

HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells

Adriano Boasso , Jean-Philippe Herbeuval , Andrew Hardy , Stephanie Anderson , Matthew Dolan et al.
Blood, 2006, 109 (8), pp.3351-3359. ⟨10.1182/blood-2006-07-034785⟩
Article dans une revue hal-04204732 v1

Differential expression of IFN-α and TRAIL/DR5 in lymphoid tissue of progressor versus nonprogressor HIV-1-infected patients

Jean-Philippe Herbeuval , Jakob Nilsson , Adriano Boasso , Andrew Hardy , Michael Kruhlak et al.
Proceedings of the National Academy of Sciences of the United States of America, 2006, 103 (18), pp.7000-7005. ⟨10.1073/pnas.0600363103⟩
Article dans une revue hal-04198879 v1

Regulation of indoleamine 2,3-dioxygenase and tryptophanyl-tRNA-synthetase by CTLA-4-Fc in human CD4+ T cells

Adriano Boasso , Jean-Philippe Herbeuval , Andrew Hardy , Christiana Winkler , Gene Shearer
Blood, 2005, 105 (4), pp.1574-1581. ⟨10.1182/blood-2004-06-2089⟩
Article dans une revue hal-04198822 v1

CD4+ T-cell death induced by infectious and noninfectious HIV-1: role of type 1 interferon-dependent, TRAIL/DR5-mediated apoptosis

Jean-Philippe Herbeuval , Jean-Charles Grivel , Adriano Boasso , Andrew Hardy , Claire Chougnet et al.
Blood, 2005, 106 (10), pp.3524-3531. ⟨10.1182/blood-2005-03-1243⟩
Article dans une revue hal-04198872 v1

TNF-related apoptosis-inducing ligand (TRAIL) in HIV-1-infected patients and its in vitro production by antigen-presenting cells

Jean-Philippe Herbeuval , Adriano Boasso , Jean-Charles Grivel , Andrew Hardy , Stephanie Anderson et al.
Blood, 2005, 105 (6), pp.2458-2464. ⟨10.1182/blood-2004-08-3058⟩
Article dans une revue hal-04198864 v1

Regulation of TNF-related apoptosis-inducing ligand on primary CD4 + T cells by HIV-1: Role of type I IFN-producing plasmacytoid dendritic cells

Jean-Philippe Herbeuval , Andrew Hardy , Adriano Boasso , Stephanie Anderson , Matthew Dolan et al.
Proceedings of the National Academy of Sciences of the United States of America, 2005, 102 (39), pp.13974-13979. ⟨10.1073/pnas.0505251102⟩
Article dans une revue hal-04198875 v1

Recruitment of STAT3 for Production of IL-10 by Colon Carcinoma Cells Induced by Macrophage-Derived IL-6

Eric Lelievre , Claude Lambert , Michel Dy , Christian Genin , Jean-Philippe Herbeuval
Journal of Immunology, 2004, 172 (7), pp.4630-4636. ⟨10.4049/jimmunol.172.7.4630⟩
Article dans une revue hal-04249987 v1

Macrophages From Cancer Patients: Analysis of TRAIL, TRAIL Receptors, and Colon Tumor Cell Apoptosis

Jean-Philippe Herbeuval , Claude Lambert , Odile Sabido , Michèle Cottier , Pierre Fournel et al.
JNCI: Journal of the National Cancer Institute, 2003, 95 (8), pp.611-621. ⟨10.1093/jnci/95.8.611⟩
Article dans une revue hal-04198816 v1

Screening the signalling behaviour of immunomodulating compounds at CXCR4

Jean Philippe Herbeuval
19th World Congress of Basic and Clinical Pharmacology (WCP), Jul 2023, Glasgow, France. pp.670-671
Communication dans un congrès hal-04255631 v1

In Vitro Functionally Selective Immunomodulator Shows Robust Efficacy in Pristane-induced Murine Lupus Model

Jean Philippe Herbeuval
19th World Congress of Basic and Clinical Pharmacology (WCP), Jul 2023, Glasgow, United Kingdom. pp.561-561
Communication dans un congrès hal-04255619 v1