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Targeting Transcription-Replication Conflicts using G-quadruplexes stabilizers in Multiple Myeloma
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Article dans une revue
lirmm-04919719
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PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression
Marion Haas
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Article dans une revue
hal-04883435
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KDM6A controls immunogenicity in MM
Jerome Moreaux
Article dans une revue
hal-04912732
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Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation
Manuela Hummel
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Article dans une revue
hal-04704595
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BHLHE41, a transcriptional repressor involved in physiological processes and tumor development
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Article dans une revue
hal-04704590
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Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation
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Article dans une revue
hal-04701434
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A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide
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Article dans une revue
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Transient loss of Polycomb components induces an epigenetic cancer fate
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Article dans une revue
hal-04581411
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FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population
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Article dans une revue
hal-04704594
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Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens
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Article dans une revue
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CD38 , CD39 , and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma
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Article dans une revue
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MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling
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Article dans une revue
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Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma
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3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness
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Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data
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Article dans une revue
hal-04705018
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Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3
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Immunophenotypic portrait of leukemia‐associated‐phenotype markers in B acute lymphoblastic leukemia
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EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
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Article dans une revue
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The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance
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Article dans une revue
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Comprehensive characterization of the epigenetic landscape in Multiple Myeloma
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Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
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miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study
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LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
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LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
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PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
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Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
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The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
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Article dans une revue
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Targeting the β 2 ‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism
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Comprehensive characterization of the epigenetic landscape in Multiple Myeloma
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Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study
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G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death
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RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma
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Article dans une revue
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
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Claire Gourzones
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Article dans une revue
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Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study
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Article dans une revue
hal-04041296
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The origin of pre-plasmablastic cells
Jerome Moreaux
Article dans une revue
hal-03243758
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
Laurie Herviou
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Fanny Izard
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Article dans une revue
hal-04707906
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The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
Benoît Manfroi
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Article dans une revue
hal-03531067
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RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma
Elina Alaterre
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Article dans une revue
hal-04707897
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
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Article dans une revue
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RNA Sequencing Data-driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators
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Article dans une revue
hal-03243729
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
Laure Dutrieux
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Article dans une revue
hal-03365519
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The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
Benoît Manfroi
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Article dans une revue
hal-04707920
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Immunotherapy perspectives in the new era of B-cell editing
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Article dans une revue
hal-03202338
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
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Article dans une revue
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Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
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Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features
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hal-02961501
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DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets
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Article dans une revue
hal-03014671
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A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment
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Article dans une revue
hal-03203259
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Kinome expression profiling to target new therapeutic avenues in multiple myeloma
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Article dans une revue
hal-02587620
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The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
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Role of Polycomb Complexes in Normal and Malignant Plasma Cells
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Article dans une revue
hal-03243763
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Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact
Julie Devin
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Article dans une revue
hal-02571739
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Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
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EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
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Article dans une revue
hal-03243777
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Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells
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Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma
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hal-02542010
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Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial
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Article dans une revue
hal-03243769
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Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner
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hal-02047561
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Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance
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Article dans une revue
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Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma
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Article dans une revue
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Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
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Anticorps anti-CD38 dans le myélome multiple
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Article dans une revue
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The Anaphase-Promoting Complex/Cyclosome: A New Promising Target in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma
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Article dans une revue
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
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Physiological and druggable skipping of immunoglobulin variable exons in plasma cells
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Article dans une revue
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[EZH2 is therapeutic target for personalized treatment in multiple myeloma].
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Article dans une revue
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An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy
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Article dans une revue
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Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression
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Article dans une revue
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PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
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Article dans une revue
hal-02315111
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DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells
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Article dans une revue
hal-01792246
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BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma
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Article dans une revue
hal-02048196
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Characterization of human FCRL4-positive B cells
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Article dans une revue
hal-01560458
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Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry
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Article dans une revue
hal-01680330
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Differential effects of lenalidomide during plasma cell differentiation
Michel Jourdan
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Article dans une revue
hal-01355076
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EZH2 in normal hematopoiesis and hematological malignancies
Laurie Herviou
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Article dans une revue
hal-01275235
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Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma
Elena Viziteu
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Anja Seckinger
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Article dans une revue
hal-01284314
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Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells
S Lub
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Article dans une revue
hal-01299387
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RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
Elena Viziteu
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Article dans une revue
inserm-01322505
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Drug metabolism and clearance system in tumor cells of patients with multiple myeloma
Wafa Hassen
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Article dans une revue
hal-01153138
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Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma
L. Vincent
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Article dans une revue
hal-01955536
v1
|
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miRNAs in multiple myeloma - a survival relevant complex regulator of gene expression
A Seckinger
,
T Meissner
,
Jérôme Moreaux
,
V. Benes
,
J Hillengass
et al.
Article dans une revue
hal-01237028
v1
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Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia
Marion Lapierre
,
Audrey Castet-Nicolas
,
Delphine Gitenay
,
Stéphan Jalaguier
,
Catherine Teyssier
et al.
Article dans une revue
hal-01153157
v1
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The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells
Niels Weinhold
,
Tobias Meissner
,
David Johnson
,
Anja Seckinger
,
Jerome Moreaux
et al.
Article dans une revue
hal-02157564
v1
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DNA repair in diffuse large B-cell lymphoma: a molecular portrait
Caroline Bret
,
Bernard Klein
,
Guillaume Cartron
,
Jean-François Schved
,
Angelos Constantinou
et al.
Article dans une revue
hal-01143993
v1
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Identification of a 20-gene expression-based risk score as a predictor of clinical outcome in chronic lymphocytic leukemia patients.
Elias Bou Samra
,
Bernard Klein
,
Thérèse Commes
,
Jérôme Moreaux
Article dans une revue
inserm-01023921
v1
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A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy
Alboukadel Kassambara
,
Claire Gourzones
,
S. Sahota
,
Thierry Rème
,
Jérôme Moreaux
et al.
Article dans une revue
hal-01006634
v1
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DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine.
Jérôme Moreaux
,
Angelique Bruyer
,
Jean-Luc Veyrune
,
Hartmut Goldschmidt
,
Dirk Hose
et al.
Article dans une revue
inserm-00906054
v1
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Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma.
Caroline Bret
,
Bernard Klein
,
Jérôme Moreaux
Article dans une revue
inserm-00840265
v1
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Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.
Alboukadel Kassambara
,
Matthieu Schoenhals
,
Jérôme Moreaux
,
Jean-Luc Veyrune
,
Thierry Rème
et al.
Article dans une revue
inserm-00840268
v1
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Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors.
Jérôme Moreaux
,
Thierry Rème
,
Wim Leonard
,
Jean-Luc Veyrune
,
Guilhem Requirand
et al.
Article dans une revue
inserm-00906782
v1
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New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients.
Elias Bou Samra
,
Jérôme Moreaux
,
Fabienne Vacheret
,
Ken Mills
,
Florence Rufflé
et al.
Article dans une revue
inserm-00681007
v1
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Clinical and prognostic role of annexin A2 in multiple myeloma.
Anja Seckinger
,
Tobias Meiβner
,
Jérôme Moreaux
,
Daniela Depeweg
,
Jens Hillengass
et al.
Article dans une revue
inserm-00726994
v1
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Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?
Anouk Caraux
,
Laure Vincent
,
Salahedine Bouhya
,
Philippe Quittet
,
Jérôme Moreaux
et al.
Oncotarget, 2012, 3 (11), pp.1335-47
Article dans une revue
inserm-00802665
v1
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Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients.
Elias Bou Samra
,
Bernard Klein
,
Thérèse Commes
,
Jérôme Moreaux
Oncotarget, 2012, 3 (8), pp.824-32
Article dans une revue
inserm-00726665
v1
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Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma.
Alboukadel Kassambara
,
Dirk Hose
,
Jérôme Moreaux
,
Brian A. Walker
,
Alexei Protopopov
et al.
Article dans une revue
inserm-00727008
v1
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Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.
Alboukadel Kassambara
,
Dirk Hose
,
Jérôme Moreaux
,
Thierry Rème
,
Jennifer Torrent
et al.
Article dans une revue
inserm-00802686
v1
|
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Gene expression-based risk score in diffuse large B-cell lymphoma.
Caroline Bret
,
Bernard Klein
,
Jérôme Moreaux
Oncotarget, 2012, 3 (12), pp.1700-10
Article dans une revue
inserm-00802570
v1
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STEAP1 is overexpressed in cancers: A promising therapeutic target.
Jérôme Moreaux
,
Alboukadel Kassambara
,
Dirk Hose
,
Bernard Klein
Article dans une revue
inserm-00760262
v1
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Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors.
Jérôme Moreaux
,
Thierry Rème
,
Wim Leonard
,
Jean-Luc Veyrune
,
Guilhem Requirand
et al.
Article dans une revue
inserm-00760269
v1
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SULFs in human neoplasia: implication as progression and prognosis factors.
Caroline Bret
,
Jérôme Moreaux
,
Jean-François Schved
,
Dirk Hose
,
Bernard Klein
Article dans une revue
inserm-00601153
v1
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Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration.
Jérôme Moreaux
,
Dirk Hose
,
Alboukadel Kassambara
,
Thierry Rème
,
Philippe Moine
et al.
Article dans une revue
inserm-00906774
v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
Jérôme Moreaux
,
Bernard Klein
,
Régis Bataille
,
Géraldine Descamps
,
Sophie Maïga
et al.
Article dans une revue
inserm-00550232
v1
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MYEOV is a prognostic factor in multiple myeloma.
Jérôme Moreaux
,
Dirk Hose
,
Amélie Bonnefond
,
Thierry Rème
,
Nicolas Robert
et al.
Article dans une revue
inserm-00906769
v1
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Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.
Karène Mahtouk
,
Jérôme Moreaux
,
Dirk Hose
,
Thierry Rème
,
Tobias Meissner
et al.
Article dans une revue
inserm-00668220
v1
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Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis.
Anja Seckinger
,
Tobias Meissner
,
Jérôme Moreaux
,
Hartmut Goldschmidt
,
Gwenny M. Fuhler
et al.
Article dans une revue
inserm-00437705
v1
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The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor.
Anne Catherine Sprynski
,
Dirk Hose
,
Laurent Caillot
,
Thierry Rème
,
John D. Shaughnessy Jr
et al.
Article dans une revue
inserm-00367812
v1
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Inhibition of Aurora-kinases for tailored risk adapted treatment of multiple myeloma.
Dirk Hose
,
Thierry Rème
,
Tobias Meissner
,
Jérôme Moreaux
,
Anja Seckinger
et al.
Article dans une revue
inserm-00368414
v1
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APRIL is overexpressed in cancer: link with tumor progression.
Jérôme Moreaux
,
Jean-Luc Veyrune
,
John de Vos
,
Bernard Klein
Article dans une revue
inserm-00369505
v1
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Induction of angiogenesis by normal and malignant plasma cells.
Dirk Hose
,
Jérôme Moreaux
,
Tobias Meissner
,
Anja Seckinger
,
Hartmut Goldschmidt
et al.
Article dans une revue
inserm-00401390
v1
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Embryonic stem cell markers expression in cancers.
Matthieu Schoenhals
,
Alboukadel Kassambara
,
John De Vos
,
Dirk Hose
,
Jérôme Moreaux
et al.
Article dans une revue
inserm-00367054
v1
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APRIL and TACI interact with syndecan-1 on the surface of multiple myeloma cells to form an essential survival loop.
Jérôme Moreaux
,
Anne-Catherine Sprynski
,
Stacey R. Dillon
,
Karène Mahtouk
,
Michel Jourdan
et al.
Article dans une revue
inserm-00397249
v1
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CD200: a putative therapeutic target in cancer.
Jérôme Moreaux
,
Jean-Luc Veyrune
,
Thierry Rème
,
John de Vos
,
Bernard Klein
Article dans une revue
inserm-00195258
v1
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MMSET is overexpressed in cancers: Link with tumor aggressiveness.
Alboukadel Kassambara
,
Bernard Klein
,
Jérôme Moreaux
Article dans une revue
inserm-00356253
v1
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Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth.
Michel Jourdan
,
Jérôme Moreaux
,
John De Vos
,
Dirk Hose
,
Karène Mahtouk
et al.
Article dans une revue
inserm-00160647
v1
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Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications.
Karène Mahtouk
,
Dirk Hose
,
John de Vos
,
Jérôme Moreaux
,
Michel Jourdan
et al.
Article dans une revue
inserm-00270566
v1
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TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines.
Jérôme Moreaux
,
Dirk Hose
,
Michel Jourdan
,
Thierry Rème
,
Michael Hundemer
et al.
Haematologica, 2007, 92 (6), pp.803-11
Article dans une revue
inserm-00162002
v1
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Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma.
Karène Mahtouk
,
Friedrich W. Cremer
,
Thierry Rème
,
Michel Jourdan
,
Marion Baudard
et al.
Article dans une revue
inserm-00128880
v1
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Microarray-based understanding of normal and malignant plasma cells.
John de Vos
,
Dirk Hose
,
Thierry Rème
,
Karin Tarte
,
Jérôme Moreaux
et al.
Article dans une revue
inserm-00149827
v1
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CD200 is a new prognostic factor in multiple myeloma.
Jérôme Moreaux
,
Dirk Hose
,
Thierry Rème
,
Eric Jourdan
,
Michael Hundemer
et al.
Article dans une revue
inserm-00130595
v1
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Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells.
Karène Mahtouk
,
Dirk Hose
,
Thierry Rème
,
John de Vos
,
Michel Jourdan
et al.
Article dans une revue
inserm-00130206
v1
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The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.
Jérôme Moreaux
,
Friedrich W. Cremer
,
Thierry Rème
,
Marc Raab
,
Karene Mahtouk
et al.
Article dans une revue
inserm-00129406
v1
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BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone.
Jérôme Moreaux
,
Eric Legouffe
,
Eric Jourdan
,
Philippe Quittet
,
Thierry Rème
et al.
Article dans une revue
inserm-00129502
v1
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Survival and proliferation factors of normal and malignant plasma cells.
Bernard Klein
,
Karin Tarte
,
Michel Jourdan
,
Karene Mathouk
,
Jérôme Moreaux
et al.
International Journal of Hematology, 2003, 78 (2), pp.106-13
Article dans une revue
inserm-00130900
v1
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