Jerome MOREAUX

Professor CNU 87, Faculty of Medicine, University Montpellier.
163
Documents
Affiliations actuelles
  • Institut de génétique humaine (IGH)
  • CHU Montpellier = Montpellier University Hospital
  • Institut National de la Santé et de la Recherche Médicale (INSERM)
  • Institut universitaire de France (IUF)
Identifiants chercheurs

Publications

Publications

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Synergistic effect of inhibiting CHK2 and DNA replication on cancer cell growth

Flavie Coquel , Sing-Zong Ho , Keng-Chang Tsai , Chun-Yen Yang , Antoine Aze et al.

eLife, 2025, 13, pp.RP104718. ⟨10.7554/eLife.104718⟩

Article dans une revue hal-05378520v1
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The de novo DNA methyltransferase 3B is a novel epigenetic regulator of MYC in multiple myeloma, representing a promising therapeutic target to counter relapse

Catharina Muylaert , Lien Ann van Hemelrijck , Arne van der Vreken , Robbe Heestermans , Hatice Satilmis et al.

Journal of experimental & clinical cancer research, 2025, 44 (1), pp.125. ⟨10.1186/s13046-025-03382-y⟩

Article dans une revue hal-05523791v1
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Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma

Laure Dutrieux , Sara Ovejero , Antoine Guillemin , Miss Leriem Zellagui , Elke de Bruyne et al.

Blood Neoplasia, 2025, 2 (2), pp.100072. ⟨10.1016/j.bneo.2025.100072⟩

Article dans une revue hal-05343640v1
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Development of a robust BH3 drug toolkit for precision medicine in hematologic malignancies

Valentin Jacquier , Andréa Romero , Caroline Molinaro , Ritu Somayaji , Matthieu Abouladze et al.

Theranostics, 2025, 15 (12), pp.5705-5718. ⟨10.7150/thno.107852⟩

Article dans une revue hal-05521232v1
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PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression

Marion Haas , Sabrina Cherfa , Léa Nguyen , Maxence Bourgoin , Gersende Caron et al.

Nature Communications, 2025, 16 (1), pp.256. ⟨10.1038/s41467-024-55572-5⟩

Article dans une revue hal-04883435v1
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Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction

Sara Ovejero , Laura Alibert , Julie Devin , Tatiana Cañeque , Valentin Jacquier et al.

Theranostics, 2025, 15 (7), pp.2834-2851. ⟨10.7150/thno.101821⟩

Article dans une revue hal-05343829v1
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Synthetic Lethal Combinations of DNA Repair Inhibitors and Genotoxic Agents to Target High‐Risk Diffuse Large B Cell Lymphoma

Sara Ovejero , Julie Devin , Laura Alibert , Camille Soun , Yea‐lih Lin et al.

Hematological Oncology, 2025, 43 (5), ⟨10.1002/hon.70131⟩

Article dans une revue hal-05515319v1
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Editing B cells at the IGHA2 gene position provides alternative route to therapeutic IgA production

Marine Cahen , Jenny Leonard , Ophélie Dézé , Laurent Deleurme , Maïwenn Pineau et al.

Mucosal Immunology, 2025, 18 (5), pp.1027-1035. ⟨10.1016/j.mucimm.2025.06.001⟩

Article dans une revue hal-05163114v1
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DIS3 licenses B cells for plasma cell differentiation in humans

Emma Miglierina , Julien Bouder , Delfina Ordanoska , Maïwenn Pineau , Simon Leonard et al.

Cellular and molecular immunology, 2025, 23 (1), pp.31-47. ⟨10.1038/s41423-025-01369-5⟩

Article dans une revue hal-05417577v1
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BHLHE41, a transcriptional repressor involved in physiological processes and tumor development

Caroline Bret , Fabienne Desmots-Loyer , Jérôme Moreaux , Thierry Fest

Cellular Oncology, 2024, Online ahead of print. ⟨10.1007/s13402-024-00973-3⟩

Article dans une revue hal-04704590v1

A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide

Denis Coulomb , Vanessa Lacheretz-Szablewski , Nicolas Robert , Anne-Marie Dupuy , Rayane Berrahouane et al.

Rheumatology, 2024, 64 (2), pp.895-897. ⟨10.1093/rheumatology/keae448⟩

Article dans une revue hal-04704591v1
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Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation

Elina Alaterre , Sara Ovejero , Caroline Bret , Laure Dutrieux , Dassou Sika et al.

Blood, 2024, 144 (5), pp.496-509. ⟨10.1182/blood.2023023237⟩

Article dans une revue hal-04701434v1
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Transient loss of Polycomb components induces an epigenetic cancer fate

Victoria Parreno , Vincent Loubiere , Bernd Schuettengruber , Lauriane Fritsch , Chetan C. Rawal et al.

Nature, 2024, 629 (8012), pp.688-696. ⟨10.1038/s41586-024-07328-w⟩

Article dans une revue hal-04581411v1
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FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population

Michaël Constantinides , Nicolas Robert , Caroline Multrier , Loïs Coënon , Mauricio Campos-Mora et al.

OncoImmunology, 2024, 13 (1), pp.2388306. ⟨10.1080/2162402X.2024.2388306⟩

Article dans une revue hal-04704594v1
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Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens

Natsuko Ueda , Marine Cahen , Jenny Leonard , Laurent Deleurme , Stéphane Dreano et al.

Scientific Reports, 2024, 14 (1), pp.22432. ⟨10.1038/s41598-024-74005-3⟩

Article dans une revue hal-04723581v1
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CD38 , CD39 , and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma

Pauline Marianini , Vanessa Lacheretz-Szablewski , Marion Almeras , Jérôme Moreaux , Caroline Bret

Cytometry Part B: Clinical Cytometry, 2024, 144 (5), pp.496-509. ⟨10.1002/cyto.b.22208⟩

Article dans une revue hal-04704587v1
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Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation

Manuela Hummel , Thomas Hielscher , Martina Emde-Rajaratnam , Hans Salwender , Susanne Beck et al.

JCO precision oncology, 2024, 8, pp.e2300613. ⟨10.1200/PO.23.00613⟩

Article dans une revue hal-04704595v1
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MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling

Hervé Técher , Diyavarshini Gopaul , Jonathan Heuzé , Nail Bouzalmad , Baptiste Leray et al.

Nature Communications, 2024, 15 (1), pp.5423. ⟨10.1038/s41467-024-49740-w⟩

Article dans une revue hal-04748159v1
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An atlas of cells in the human tonsil

Ramon Massoni-Badosa , Sergio Aguilar-Fernández , Juan C. Nieto , Paula Soler-Vila , Marc Elosua-Bayes et al.

Immunity, 2024, 57 (2), pp.379-399.e18. ⟨10.1016/j.immuni.2024.01.006⟩

Article dans une revue hal-04704602v1

KDM6A controls immunogenicity in MM

Jerome Moreaux

Blood, 2024, 144 (14), pp.1465-1467. ⟨10.1182/blood.2024026013⟩

Article dans une revue hal-04912732v1
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Editorial: Transcriptional control in normal and malignant B-lymphocytes

Jérôme Moreaux , Alexander A. Shtil

Frontiers in Immunology, 2023, 14, pp.1185252. ⟨10.3389/fimmu.2023.1185252⟩

Article dans une revue hal-04705020v1
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RNA-sequencing based first choice of treatment and determination of risk in multiple myeloma

Martina Emde-Rajaratnam , Susanne Beck , Vladimir Benes , Hans Salwender , Uta Bertsch et al.

Frontiers in Immunology, 2023, 14, pp.1286700. ⟨10.3389/fimmu.2023.1286700⟩

Article dans une revue hal-04704606v1

3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness

L. Baert , B. Manfroi , M. Quintero , O. Chavarria , P.V. Barbon et al.

Matrix Biology, 2023, 120, pp.60-75. ⟨10.1016/j.matbio.2023.05.005⟩

Article dans une revue hal-04444452v1
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Immunophenotypic portrait of leukemia‐associated‐phenotype markers in B acute lymphoblastic leukemia

Emilia Boris , Alexandre Theron , Valentin Montagnon , Nicolas Rouquier , Marion Almeras et al.

Cytometry Part B: Clinical Cytometry, 2023, 106 (1), pp.45-57. ⟨10.1002/cyto.b.22153⟩

Article dans une revue hal-04704605v1
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Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma

Angélique Bruyer , Laure Dutrieux , Hugues de Boussac , Thibaut Martin , Djamila Chemlal et al.

Frontiers in Oncology, 2023, 13, pp.1271847. ⟨10.3389/fonc.2023.1271847⟩

Article dans une revue hal-04704603v1
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Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data

Mohammad Salma , Elina Alaterre , Jérôme Moreaux , Eric Soler

Epigenetics & Chromatin, 2023, 16 (1), pp.23. ⟨10.1186/s13072-023-00497-4⟩

Article dans une revue hal-04705018v1
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Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3

Sarah Bonnet , Serge Carillo , Baptiste Legrand , Barbara Burroni , Thierry Lavabre-Bertrand et al.

European Journal of Haematology, 2023, 112 (3), pp.475-478. ⟨10.1111/ejh.14126⟩

Article dans une revue hal-04550049v1
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S-adenosylmethionine biosynthesis is a targetable metabolic vulnerability in multiple myeloma

Yanmeng Wang , Catharina Muylaert , Arne Wyns , Philip Vlummens , Kim de Veirman et al.

Haematologica, 2023, 109, pp.256-271. ⟨10.3324/haematol.2023.282866⟩

Article dans une revue hal-04705017v1
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EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma

Djamila Chemlal , Emmanuel Varlet , Amelie Machura , Sara Ovejero , Guilhem Requirand et al.

Leukemia, 2023, 37 (9), pp.1925-1928. ⟨10.1038/s41375-023-01983-0⟩

Article dans une revue hal-04252294v1
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Comprehensive characterization of the epigenetic landscape in Multiple Myeloma

Elina Alaterre , Sara Ovejero , Laurie Herviou , Hugues de Boussac , Giorgio Papadopoulos et al.

Theranostics, 2022, 12 (4), pp.1715-1729. ⟨10.7150/thno.54453⟩

Article dans une revue hal-03810219v1
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The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance

Sara Ovejero , Elena Viziteu , Laure Dutrieux , Julie Devin , Yea-Lih Lin et al.

Frontiers in Immunology, 2022, 13, pp.983181. ⟨10.3389/fimmu.2022.983181⟩

Article dans une revue (data paper) hal-04021632v1
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miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study

Isabelle Duroux-Richard , Anne-Laure Gagez , Elina Alaterre , Rémi Letestu , Olfa Khalifa et al.

Frontiers in Immunology, 2022, 13, pp.983771. ⟨10.3389/fimmu.2022.983771⟩

Article dans une revue hal-03946290v1
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PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma

Marion Haas , Gersende Caron , Fabrice Chatonnet , Stéphane Manenti , Elina Alaterre et al.

Blood, 2022, 139 (15), pp.2316-2337. ⟨10.1182/blood.2021014011⟩

Article dans une revue hal-04822853v2
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Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma

Julie Devin , Tatiana Cañeque , Yea-Lih Lin , Lucie Mondoulet , Jean-Luc Veyrune et al.

Cancer Research, 2022, 82 (6), pp.998-1012. ⟨10.1158/0008-5472.CAN-21-0218⟩

Article dans une revue hal-04053839v1
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LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms

François van Laethem , Lucie Donaty , Emmanuelle Tchernonog , Vanessa Lacheretz-Szablewski , Jennifer Russello et al.

International Journal of Molecular Sciences, 2022, 23 (24), pp.16136. ⟨10.3390/ijms232416136⟩

Article dans une revue hal-03980144v1
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The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias

Rosa Paolillo , Mathias Boulanger , Pierre Gâtel , Ludovic Gabellier , Marion de Toledo et al.

Haematologica, 2022, 107 (11), pp.2562-2575. ⟨10.3324/haematol.2021.279889⟩

Article dans une revue hal-03759821v2
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Targeting the β 2 ‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism

Hatice Satilmis , Emma Verheye , Philip Vlummens , Inge Oudaert , Niels Vandewalle et al.

Journal of Pathology, 2022, 259 (1), pp.69-80. ⟨10.1002/path.6020⟩

Article dans une revue hal-04590992v1

Inhibition of the Protein Arginine Methyltransferase PRMT5 in High-Risk Multiple Myeloma as a Novel Treatment Approach

Philip Vlummens , Stefaan Verhulst , Kim de Veirman , Anke Maes , Eline Menu et al.

Frontiers in Cell and Developmental Biology, 2022, 10, ⟨10.3389/fcell.2022.879057⟩

Article dans une revue hal-04705562v1
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RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma

Elina Alaterre , Veronika Vikova , Alboukadel Kassambara , Angélique Bruyer , Nicolas Robert et al.

Journal of Personalized Medicine, 2021, 11 (10), pp.988. ⟨10.3390/jpm11100988⟩

Article dans une revue hal-03639307v1
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The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5

Benoît Manfroi , Maria de Grandis , Jérôme Moreaux , Sébastien Tabruyn , Jean-François Mayol et al.

Blood Advances, 2021, 5 (21), pp.4338-4351. ⟨10.1182/bloodadvances.2021004203⟩

Article dans une revue hal-04444537v1
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Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types

Maksim Erokhin , Olga Chetverina , Balázs Győrffy , Victor Tatarskiy , Vladic Mogila et al.

Cancers, 2021, 13 (13), pp.3155. ⟨10.3390/cancers13133155⟩

Article dans une revue hal-03693300v1
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Discovery of candidate DNA methylation cancer driver genes

Heng Pan , Loic Renaud , Ronan Chaligne , Johannes Bloehdorn , Eugen Tausch et al.

Cancer Discovery, 2021, pp.candisc.1334.2020. ⟨10.1158/2159-8290.CD-20-1334⟩

Article dans une revue hal-03243749v1
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

Laurie Herviou , Sara Ovejero , Fanny Izard , Ouissem Karmous-Gadacha , Claire Gourzones et al.

Clinical Epigenetics, 2021, 13 (1), ⟨10.1186/s13148-021-01160-z⟩

Article dans une revue hal-03450559v1
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The origin of pre-plasmablastic cells

Jerome Moreaux

Blood, 2021, 137 (9), pp.1134-1135. ⟨10.1182/blood.2020009746⟩

Article dans une revue hal-03243758v1
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RNA Sequencing Data-driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators

Alboukadel Kassambara , Laurie Herviou , Sara Ovejero , Michel Jourdan , Coraline Thibaut et al.

Leukemia, 2021, 35 (5), pp.1451-1462. ⟨10.1038/s41375-021-01234-0⟩

Article dans une revue hal-03243729v1
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Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Raphaël Rodriguez , Michel Cogné et al.

Cancers, 2021, 13 (15), pp.3755. ⟨10.3390/cancers13153755⟩

Article dans une revue hal-03365519v1
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Immunotherapy perspectives in the new era of B-cell editing

Natsuko Ueda , Marine Cahen , Yannic Danger , Jérôme Moreaux , Christophe Sirac et al.

Blood Advances, 2021, 5 (6), pp.1770-1779. ⟨10.1182/bloodadvances.2020003792⟩

Article dans une revue hal-03202338v1

Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study

Anne-Laure Gagez , Franciane Paul , Elina Alaterre , Valérie Gouilleux-Gruart , Edouard Tuaillon et al.

Leukemia & lymphoma, 2021, 62 (13), pp.3160-3169. ⟨10.1080/10428194.2021.1955879⟩

Article dans une revue hal-03640354v1
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G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death

Eva de Smedt , Julie Devin , Catharina Muylaert , Nicolas Robert , Guilhem Requirand et al.

Blood Advances, 2021, 5 (9), pp.2325-2338. ⟨10.1182/bloodadvances.2020003217⟩

Article dans une revue hal-03243723v1
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Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites

J. Basbous , Antoine Aze , Laurent Chaloin , Rana Lebdy , Dana Hodroj et al.

Nucleic Acids Research, 2020, 48 (4), pp.1886-1904. ⟨10.1093/nar/gkz1162⟩

Article dans une revue hal-02556387v1
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DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets

Ludovic Gabellier , Caroline Bret , Guillaume Bossis , Guillaume Cartron , Jérôme Moreaux

Cancers, 2020, 12 (10), pp.2874. ⟨10.3390/cancers12102874⟩

Article dans une revue hal-03014671v1
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Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features

Orianne Villard , Mathieu Armanet , Guilhem Couderc , Claire Bony , Jerome Moreaux et al.

Stem Cell Research and Therapy, 2020, 11, pp.158. ⟨10.1186/s13287-020-01649-z⟩

Article dans une revue hal-02961501v1
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Kinome expression profiling to target new therapeutic avenues in multiple myeloma

Hugues de Boussac , Angelique Bruyer , Michel Jourdan , Anke Maes , Nicolas N. Robert et al.

Haematologica, 2020, 105 (3), pp.784-795. ⟨10.3324/haematol.2018.208306⟩

Article dans une revue hal-02587620v1
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A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment

Sylvain Lamure , Franciane Paul , Anne-Laure Gagez , Jérémy Delage , Laure Vincent et al.

Journal of Clinical Medicine, 2020, 9 (7), pp.2204. ⟨10.3390/jcm9072204⟩

Article dans une revue hal-03203259v1
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The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation

Fabrice Chatonnet , Amandine Pignarre , Aurelien Serandour , Gersende Caron , Stéphane Avner et al.

Haematologica, 2020, 105 (3), pp.774-783. ⟨10.3324/haematol.2019.222133⟩

Article dans une revue hal-02165596v1
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Role of Polycomb Complexes in Normal and Malignant Plasma Cells

Emmanuel Varlet , Sara Ovejero , Anne-Marie Martinez , Giacomo Cavalli , Jerome Moreaux

International Journal of Molecular Sciences, 2020, 21 (21), pp.8047. ⟨10.3390/ijms21218047⟩

Article dans une revue hal-03243763v1
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EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation

Laurie Herviou , Michel Jourdan , Anne-Marie Martinez , Giacomo Cavalli , Jerome Moreaux

Leukemia, 2019, 33 (8), pp.2047-2060. ⟨10.1038/s41375-019-0392-1⟩

Article dans une revue hal-03243777v1
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Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells

Claire Gourzones , Céline Bellanger , Sylvain Lamure , Ouissem Karmous Gadacha , Elvira Garcia de Paco et al.

Cancers, 2019, 11 (4), pp.439. ⟨10.3390/cancers11040439⟩

Article dans une revue hal-02870153v1

RNA-Sequencing Based Assessment of Targets, Risk and Long Term Survival for Personalized Treatment of Multiple Myeloma

Martina Emde , Susanne Beck , Vladimir Benes , Jerome Moreaux , Anja Seckinger et al.

Blood, 2019, 134 (Supplement_1), pp.1801-1801. ⟨10.1182/blood-2019-131159⟩

Article dans une revue hal-05529873v1
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Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma

Anke Maes , Ken Maes , Philip Vlummens , Hendrik de Raeve , Julie Devin et al.

Blood Cancer Journal, 2019, 9 (12), ⟨10.1038/s41408-019-0249-x⟩

Article dans une revue hal-02542010v1
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Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial

Dirk Hose , Susanne Beck , Hans Salwender , Martina Emde , Uta Bertsch et al.

Journal of Hematology and Oncology, 2019, 12, pp.65. ⟨10.1186/s13045-019-0750-5⟩

Article dans une revue hal-03243769v1

Ironomycin Induces Diffuse Large B-Cell Lymphoma Cell Death By Targeting Iron Metabolism Addiction

Julie Devin , Tatiana Cañeque , Yea-Lih Lin , Guillaume Cartron , Philippe Pasero et al.

Blood, 2019, 134 (Supplement_1), pp.3960-3960. ⟨10.1182/blood-2019-129954⟩

Article dans une revue hal-05529967v1
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Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance

Veronika Vikova , Michel Jourdan , Nicolas Robert , Guilhem Requirand , Stephanie Boireau et al.

Theranostics, 2019, 9 (2), pp.540-553. ⟨10.7150/thno.28374⟩

Article dans une revue hal-02883457v1
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Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner

Julien Bianco , Valérie Bergoglio , Yea-Lih Lin , Marie-Jeanne Pillaire , Anne-Lyne Schmitz et al.

Nature Communications, 2019, 10 (1), pp.910. ⟨10.1038/s41467-019-08886-8⟩

Article dans une revue hal-02047561v1
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Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma

Claire Gourzones , Caroline Bret , Jérôme Moreaux

Frontiers in Genetics, 2019, 10, pp.861. ⟨10.3389/fgene.2019.00861⟩

Article dans une revue hal-02552817v1
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Anticorps anti-CD38 dans le myélome multiple

Jérôme Moreaux

Médecine/Sciences, 2019, 35 (12), pp.1001-1004. ⟨10.1051/medsci/2019198⟩

Article dans une revue hal-03243767v1

Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway

Kim de Veirman , Eline Menu , Ken Maes , Nathan de Beule , Eva de Smedt et al.

Cancer Letters, 2019, 442, pp.233-241. ⟨10.1016/j.canlet.2018.11.002⟩

Article dans une revue hal-01980419v1
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The Anaphase-Promoting Complex/Cyclosome: A New Promising Target in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma

Anke Maes , Ken Maes , Hendrik de Raeve , Eva de Smedt , Philip Vlummens et al.

British Journal of Cancer, 2019, 120 (12), pp.1137--1146. ⟨10.1038/s41416-019-0471-0⟩

Article dans une revue hal-02862214v1
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Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma

Laurie Herviou , Fanny Izard , Ouissem Karmous-Gadacha , Claire Gourzones , Celine Bellanger et al.

BioRxiv, In press, ⟨10.1101/776930⟩

Article dans une revue hal-02355848v1

In Vitro Differentiation Model of Human Normal Memory B Cells to Long-lived Plasma Cells

Michel Jourdan , Hugues de Boussac , Elena Viziteu , Alboukadel Kassambara , Jérôme Moreaux

Journal of visualized experiments : JoVE, 2019, 143, ⟨10.3791/58929⟩

Article dans une revue hal-05510019v1

Prediction of Malingant Plasma Cell Biology Related Survival in AL-Amyloidosis

Susanne Beck , Martina Emde , Jerome Moreaux , Anja Seckinger , Dirk Hose

Blood, 2019, 134 (Supplement_1), pp.3078-3078. ⟨10.1182/blood-2019-131161⟩

Article dans une revue hal-05530335v1

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer

Eve Combès , Augusto Andrade , Diego Tosi , Henri-Alexandre Michaud , Flavie Coquel et al.

Cancer Research, 2019, 79 (11), pp.2933-2946. ⟨10.1158/0008-5472.CAN-18-2807⟩

Article dans une revue hal-02361669v1
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Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact

Julie Devin , Alboukadel Kassambara , Angelique Bruyer , Jérôme Moreaux , Caroline Bret

Journal of Clinical Medicine, 2019, 8 (7), pp.1074. ⟨10.3390/jcm8071074⟩

Article dans une revue hal-02571739v1
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An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy

Vanessa Szablewski , Caroline Bret , Alboukadel Kassambara , Julie Devin , Guillaume Cartron et al.

Oncotarget, 2018, 9 (27), pp.19079--19099. ⟨10.18632/oncotarget.24901⟩

Article dans une revue hal-02345949v1

Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression

Eva de Smedt , Ken Maes , Stefaan Verhulst , Hui Lui , Alboukadel Kassambara et al.

Cancer Research, 2018, 78 (5), pp.1155 - 1168. ⟨10.1158/0008-5472.CAN-17-1544⟩

Article dans une revue hal-01864144v1
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PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs

Laurie Herviou , Alboukadel Kassambara , Stéphanie Boireau , Nicolas Robert , Guilhem Requirand et al.

Clinical Epigenetics, 2018, 10, pp.121. ⟨10.1186/s13148-018-0554-4⟩

Article dans une revue hal-02315111v1
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DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells

Angelique Bruyer , Ken Maes , Laurie Herviou , Alboukadel Kassambara , Anja Seckinger et al.

British Journal of Cancer, 2018, 118 (8), pp.1062 - 1073. ⟨10.1038/s41416-018-0025-x⟩

Article dans une revue hal-01792246v1

BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma

Guilhem Requirand , Nicolas Robert , Stéphanie Boireau , Laure Vincent , Anja Seckinger et al.

Cytometry Part B: Clinical Cytometry, 2018, ⟨10.1002/cyto.b.21730⟩

Article dans une revue hal-02048196v1

Physiological and druggable skipping of immunoglobulin variable exons in plasma cells

Mohamad Omar Ashi , Nivine Srour , Jean-Marie Lambert , Anne Marchalot , Ophélie Martin et al.

Cellular and molecular immunology, 2018, ⟨10.1038/s41423-018-0160-6⟩

Article dans une revue hal-02048156v1

[EZH2 is therapeutic target for personalized treatment in multiple myeloma].

Laurie Herviou , Giacomo Cavalli , Jérôme Moreaux

Bulletin du Cancer, 2018, 105 (9), pp.804 - 819. ⟨10.1016/j.bulcan.2018.06.003⟩

Article dans une revue hal-01904689v1
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Tumor-associated neutrophils correlate with poor prognosis in diffuse large B-cell lymphoma patients

B. Manfroi , J. Moreaux , C. Righini , F. Ghiringhelli , N. Sturm et al.

Blood Cancer Journal, 2018, 8 (7), pp.66. ⟨10.1038/s41408-018-0099-y⟩

Article dans une revue hal-01859413v1
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Global miRNA expression analysis identifies novel key regulators of plasma cell differentiation and malignant plasma cell

A Kassambara , M Jourdan , A Bruyer , N Robert , V Pantesco et al.

Nucleic Acids Research, 2017, 45 (10), pp.5639-5652. ⟨10.1093/nar/gkx327⟩

Article dans une revue hal-01533425v1

Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry

Elina Alaterre , Sébastien Raimbault , Jean-Michel Garcia , Thierry Rème , Guilhem Requirand et al.

Cytometry Part B: Clinical Cytometry, 2017, ⟨10.1002/cyto.b.21590⟩

Article dans une revue hal-01680330v1
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RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myeloma

E Viziteu , B Klein , J. Basbous , Yea-Lih Lin , Christophe Hirtz et al.

Leukemia, 2017, 31 (10), pp.2104 - 2113. ⟨10.1038/leu.2017.54⟩

Article dans une revue hal-01630891v1
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Hypoxia favors the generation of human plasma cells

M Schoenhals , M Jourdan , A Bruyer , A Kassambara , B Klein et al.

Cell Cycle, 2017, 1, pp.14. ⟨10.1080/15384101.2017.1317408⟩

Article dans une revue hal-01529310v1
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Characterization of human FCRL4-positive B cells

Michel Jourdan , Nicolas Robert , Maïlys Cren , Coraline Thibaut , Christophe Duperray et al.

PLoS ONE, 2017, 12 (6), pp.e0179793. ⟨10.1371/journal.pone.0179793⟩

Article dans une revue hal-01560458v1
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Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma

Elena Viziteu , Camille Grandmougin , Harmut Goldschmidt , Anja Seckinger , Dirk Hose et al.

British Journal of Cancer, 2016, 114 (5), pp.519-523. ⟨10.1038/bjc.2016.20⟩

Article dans une revue hal-01284314v1

Identifying high-risk adult AML patients: epigenetic and genetic risk factors and their implications for therapy

C Bret , E Viziteu , A Kassambara , J Moreaux

Expert Review of Hematology, 2016, 9 (4), pp.351-360. ⟨10.1586/17474086.2016.1141673⟩

Article dans une revue hal-01299313v1
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Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells

S Lub , A Maes , K Maes , K de Veirman , E de Bruyne et al.

Oncotarget, 2016, 7 (4), pp.4061-4076. ⟨10.18632/oncotarget.6768⟩

Article dans une revue hal-01299387v1
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RECQ helicases are deregulated in hematological malignancies in association with a prognostic value

Elena Viziteu , Alboukadel Kassambara , Philippe Pasero , Bernard Klein , Jerome Moreaux

Biomarker Research, 2016, 4, pp.3. ⟨10.1186/s40364-016-0057-4⟩

Article dans une revue inserm-01322505v1
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Differential effects of lenalidomide during plasma cell differentiation

Michel Jourdan , Maïlys Cren , Peter A Schäfer , Nicolas Robert , Christophe Duperray et al.

Oncotarget, 2016, 7 (19), pp.28096-28111. ⟨10.18632/oncotarget.8581⟩

Article dans une revue hal-01355076v1
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EZH2 in normal hematopoiesis and hematological malignancies

Laurie Herviou , Giacomo Cavalli , Guillaume Cartron , Bernard Klein , Jérôme Moreaux

Oncotarget, 2016, 7 (3), pp.2284-2296. ⟨10.18632/oncotarget.6198⟩

Article dans une revue hal-01275235v1
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Drug metabolism and clearance system in tumor cells of patients with multiple myeloma

Wafa Hassen , Alboukadel Kassambara , Thierry Rème , S Sahota , A Seckinger et al.

Oncotarget, 2015, 6 (8), pp.6431-6447. ⟨10.18632/oncotarget.3237⟩

Article dans une revue hal-01153138v1
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Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma

L. Vincent , P. Ceballos , Carine Plassot , J. C. Méniane , P. Quittet et al.

Blood Cancer Journal, 2015, 5 (8), pp.e341-e341. ⟨10.1038/bcj.2015.48⟩

Article dans une revue hal-01955536v1
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miRNAs in multiple myeloma - a survival relevant complex regulator of gene expression

A Seckinger , T Meissner , Jérôme Moreaux , V. Benes , J Hillengass et al.

Oncotarget, 2015, 6 (36), pp.39165-39183. ⟨10.18632/oncotarget.5381⟩

Article dans une revue hal-01237028v1
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Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia

Marion Lapierre , Audrey Castet-Nicolas , Delphine Gitenay , Stéphan Jalaguier , Catherine Teyssier et al.

Journal of Hematology and Oncology, 2015, 8 (1), pp.20. ⟨10.1186/s13045-015-0116-6⟩

Article dans une revue hal-01153157v1
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In vivo treatment with epigenetic modulating agents induces transcriptional alterations associated with prognosis and immunomodulation in multiple myeloma

K Maes , E de Smedt , A Kassambara , D Hose , A Seckinger et al.

Oncotarget, 2015, 6 (5), pp.3319-3334. ⟨10.18632/oncotarget.3207⟩

Article dans une revue hal-01153601v1

DNA repair in diffuse large B-cell lymphoma: a molecular portrait

Caroline Bret , Bernard Klein , Guillaume Cartron , Jean-François Schved , Angelos Constantinou et al.

British Journal of Haematology, 2015, 169 (2), pp.296-299. ⟨10.1111/bjh.13206⟩

Article dans une revue hal-01143993v1
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The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells

Niels Weinhold , Tobias Meissner , David Johnson , Anja Seckinger , Jerome Moreaux et al.

Haematologica, 2015, 100 (3), pp.e110-e113. ⟨10.3324/haematol.2014.118786⟩

Article dans une revue hal-02157564v1
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A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy

Alboukadel Kassambara , Claire Gourzones , S. Sahota , Thierry Rème , Jérôme Moreaux et al.

Oncotarget, 2014, 5 (9), pp.2487-2498. ⟨10.18632/oncotarget.1740⟩

Article dans une revue hal-01006634v1
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DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine.

Jérôme Moreaux , Angelique Bruyer , Jean-Luc Veyrune , Hartmut Goldschmidt , Dirk Hose et al.

British Journal of Haematology, 2014, 164 (4), pp.613-6. ⟨10.1111/bjh.12660⟩

Article dans une revue inserm-00906054v1
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Identification of a 20-gene expression-based risk score as a predictor of clinical outcome in chronic lymphocytic leukemia patients.

Elias Bou Samra , Bernard Klein , Thérèse Commes , Jérôme Moreaux

BioMed Research International , 2014, 2014, pp.423174. ⟨10.1155/2014/423174⟩

Article dans une revue inserm-01023921v1
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Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma.

Caroline Bret , Bernard Klein , Jérôme Moreaux

Cell Cycle, 2013, 12 (12), pp.1811-2. ⟨10.4161/cc.25115⟩

Article dans une revue inserm-00840265v1
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Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.

Alboukadel Kassambara , Matthieu Schoenhals , Jérôme Moreaux , Jean-Luc Veyrune , Thierry Rème et al.

PLoS ONE, 2013, 8 (4), pp.e62752. ⟨10.1371/journal.pone.0062752⟩

Article dans une revue inserm-00840268v1
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Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors.

Jérôme Moreaux , Thierry Rème , Wim Leonard , Jean-Luc Veyrune , Guilhem Requirand et al.

British Journal of Cancer, 2013, 109 (3), pp.676-85. ⟨10.1038/bjc.2013.392⟩

Article dans une revue inserm-00906782v1
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Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients.

Elias Bou Samra , Bernard Klein , Thérèse Commes , Jérôme Moreaux

Oncotarget, 2012, 3 (8), pp.824-32

Article dans une revue inserm-00726665v1
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Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma.

Alboukadel Kassambara , Dirk Hose , Jérôme Moreaux , Brian A. Walker , Alexei Protopopov et al.

Haematologica, 2012, 97 (4), pp.622-30. ⟨10.3324/haematol.2011.046821⟩

Article dans une revue inserm-00727008v1
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Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.

Alboukadel Kassambara , Dirk Hose , Jérôme Moreaux , Thierry Rème , Jennifer Torrent et al.

PLoS ONE, 2012, 7 (7), pp.e42161. ⟨10.1371/journal.pone.0042161⟩

Article dans une revue inserm-00802686v1
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Gene expression-based risk score in diffuse large B-cell lymphoma.

Caroline Bret , Bernard Klein , Jérôme Moreaux

Oncotarget, 2012, 3 (12), pp.1700-10

Article dans une revue inserm-00802570v1
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Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors.

Jérôme Moreaux , Thierry Rème , Wim Leonard , Jean-Luc Veyrune , Guilhem Requirand et al.

Molecular Cancer Therapeutics, 2012, 11 (12), pp.2685-92. ⟨10.1158/1535-7163.MCT-12-0721⟩

Article dans une revue inserm-00760269v1
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STEAP1 is overexpressed in cancers: A promising therapeutic target.

Jérôme Moreaux , Alboukadel Kassambara , Dirk Hose , Bernard Klein

Biochemical and Biophysical Research Communications, 2012, epub ahead of print. ⟨10.1016/j.bbrc.2012.10.123⟩

Article dans une revue inserm-00760262v1
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Clinical and prognostic role of annexin A2 in multiple myeloma.

Anja Seckinger , Tobias Meiβner , Jérôme Moreaux , Daniela Depeweg , Jens Hillengass et al.

Blood, 2012, 120 (5), pp.1087-94. ⟨10.1182/blood-2012-03-415588⟩

Article dans une revue inserm-00726994v1
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New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients.

Elias Bou Samra , Jérôme Moreaux , Fabienne Vacheret , Ken Mills , Florence Rufflé et al.

British Journal of Haematology, 2012, 157 (3), pp.347-56. ⟨10.1111/j.1365-2141.2012.09069.x⟩

Article dans une revue inserm-00681007v1
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Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?

Anouk Caraux , Laure Vincent , Salahedine Bouhya , Philippe Quittet , Jérôme Moreaux et al.

Oncotarget, 2012, 3 (11), pp.1335-47

Article dans une revue inserm-00802665v1
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SULFs in human neoplasia: implication as progression and prognosis factors.

Caroline Bret , Jérôme Moreaux , Jean-François Schved , Dirk Hose , Bernard Klein

Journal of Translational Medicine, 2011, 9 (1), pp.72. ⟨10.1186/1479-5876-9-72⟩

Article dans une revue inserm-00601153v1
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Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration.

Jérôme Moreaux , Dirk Hose , Alboukadel Kassambara , Thierry Rème , Philippe Moine et al.

Blood, 2011, 117 (4), pp.1280-90. ⟨10.1182/blood-2010-04-279760⟩

Article dans une revue inserm-00906774v1
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A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.

Jérôme Moreaux , Bernard Klein , Régis Bataille , Géraldine Descamps , Sophie Maïga et al.

Haematologica, 2011, 96 (4), pp.574-82. ⟨10.3324/haematol.2010.033456⟩

Article dans une revue inserm-00550232v1
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Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.

Karène Mahtouk , Jérôme Moreaux , Dirk Hose , Thierry Rème , Tobias Meissner et al.

BMC Cancer, 2010, 10 (1), pp.198. ⟨10.1186/1471-2407-10-198⟩

Article dans une revue inserm-00668220v1
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MYEOV is a prognostic factor in multiple myeloma.

Jérôme Moreaux , Dirk Hose , Amélie Bonnefond , Thierry Rème , Nicolas Robert et al.

Experimental Hematology, 2010, 38 (12), pp.1189-1198.e3. ⟨10.1016/j.exphem.2010.09.002⟩

Article dans une revue inserm-00906769v1
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Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis.

Anja Seckinger , Tobias Meissner , Jérôme Moreaux , Hartmut Goldschmidt , Gwenny M. Fuhler et al.

Oncogene, 2009, 28 (44), pp.3866-79. ⟨10.1038/onc.2009.257⟩

Article dans une revue inserm-00437705v1
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The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor.

Anne Catherine Sprynski , Dirk Hose , Laurent Caillot , Thierry Rème , John D. Shaughnessy Jr et al.

Blood, 2009, 113 (19), pp.4614-4626. ⟨10.1182/blood-2008-07-170464⟩

Article dans une revue inserm-00367812v1
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Inhibition of Aurora-kinases for tailored risk adapted treatment of multiple myeloma.

Dirk Hose , Thierry Rème , Tobias Meissner , Jérôme Moreaux , Anja Seckinger et al.

Blood, 2009, 113 (18), pp.4331-4340. ⟨10.1182/blood-2008-09-178350⟩

Article dans une revue inserm-00368414v1
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APRIL is overexpressed in cancer: link with tumor progression.

Jérôme Moreaux , Jean-Luc Veyrune , John de Vos , Bernard Klein

BMC Cancer, 2009, 9 (1), pp.83. ⟨10.1186/1471-2407-9-83⟩

Article dans une revue inserm-00369505v1
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Induction of angiogenesis by normal and malignant plasma cells.

Dirk Hose , Jérôme Moreaux , Tobias Meissner , Anja Seckinger , Hartmut Goldschmidt et al.

Blood, 2009, 114, pp.128-143. ⟨10.1182/blood-2008-10-184226⟩

Article dans une revue inserm-00401390v1
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Embryonic stem cell markers expression in cancers.

Matthieu Schoenhals , Alboukadel Kassambara , John De Vos , Dirk Hose , Jérôme Moreaux et al.

Biochemical and Biophysical Research Communications, 2009, 383, pp.157-162. ⟨10.1016/j.bbrc.2009.02.156⟩

Article dans une revue inserm-00367054v1
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APRIL and TACI interact with syndecan-1 on the surface of multiple myeloma cells to form an essential survival loop.

Jérôme Moreaux , Anne-Catherine Sprynski , Stacey R. Dillon , Karène Mahtouk , Michel Jourdan et al.

European Journal of Haematology, 2009, 83 (2), pp.119-29. ⟨10.1111/j.1600-0609.2009.01262.x⟩

Article dans une revue inserm-00397249v1
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CD200: a putative therapeutic target in cancer.

Jérôme Moreaux , Jean-Luc Veyrune , Thierry Rème , John de Vos , Bernard Klein

Biochemical and Biophysical Research Communications, 2008, 366 (1), pp.117-22. ⟨10.1016/j.bbrc.2007.11.103⟩

Article dans une revue inserm-00195258v1
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MMSET is overexpressed in cancers: Link with tumor aggressiveness.

Alboukadel Kassambara , Bernard Klein , Jérôme Moreaux

Biochemical and Biophysical Research Communications, 2008, 379, pp.840-845. ⟨10.1016/j.bbrc.2008.12.093⟩

Article dans une revue inserm-00356253v1
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Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth.

Michel Jourdan , Jérôme Moreaux , John De Vos , Dirk Hose , Karène Mahtouk et al.

British Journal of Haematology, 2007, 138 (2), pp.160-8. ⟨10.1111/j.1365-2141.2007.06629.x⟩

Article dans une revue inserm-00160647v1
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Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications.

Karène Mahtouk , Dirk Hose , John de Vos , Jérôme Moreaux , Michel Jourdan et al.

Clinical Cancer Research, 2007, 13 (24), pp.7289-95. ⟨10.1158/1078-0432.CCR-07-1758⟩

Article dans une revue inserm-00270566v1
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TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines.

Jérôme Moreaux , Dirk Hose , Michel Jourdan , Thierry Rème , Michael Hundemer et al.

Haematologica, 2007, 92 (6), pp.803-11

Article dans une revue inserm-00162002v1
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Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma.

Karène Mahtouk , Friedrich W. Cremer , Thierry Rème , Michel Jourdan , Marion Baudard et al.

Oncogene, 2006, 25 (54), pp.7180-91. ⟨10.1038/sj.onc.1209699⟩

Article dans une revue inserm-00128880v1
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CD200 is a new prognostic factor in multiple myeloma.

Jérôme Moreaux , Dirk Hose , Thierry Rème , Eric Jourdan , Michael Hundemer et al.

Blood, 2006, 108 (13), pp.4194-7. ⟨10.1182/blood-2006-06-029355⟩

Article dans une revue inserm-00130595v1
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Microarray-based understanding of normal and malignant plasma cells.

John de Vos , Dirk Hose , Thierry Rème , Karin Tarte , Jérôme Moreaux et al.

Immunological Reviews, 2006, 210, pp.86-104. ⟨10.1111/j.0105-2896.2006.00362.x⟩

Article dans une revue inserm-00149827v1
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Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells.

Karène Mahtouk , Dirk Hose , Thierry Rème , John de Vos , Michel Jourdan et al.

Oncogene, 2005, 24 (21), pp.3512-24. ⟨10.1038/sj.onc.1208536⟩

Article dans une revue inserm-00130206v1
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The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.

Jérôme Moreaux , Friedrich W. Cremer , Thierry Rème , Marc Raab , Karene Mahtouk et al.

Blood, 2005, 106 (3), pp.1021-30. ⟨10.1182/blood-2004-11-4512⟩

Article dans une revue inserm-00129406v1
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BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone.

Jérôme Moreaux , Eric Legouffe , Eric Jourdan , Philippe Quittet , Thierry Rème et al.

Blood, 2004, 103 (8), pp.3148-57. ⟨10.1182/blood-2003-06-1984⟩

Article dans une revue inserm-00129502v1
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Survival and proliferation factors of normal and malignant plasma cells.

Bernard Klein , Karin Tarte , Michel Jourdan , Karene Mathouk , Jérôme Moreaux et al.

International Journal of Hematology, 2003, 78 (2), pp.106-13

Article dans une revue inserm-00130900v1

Abstract C047: Unraveling proteotoxic and oxidative stress - driven adaptations in multiple myeloma

Despoina D. Gianniou , Eirini Gkogkou , Paraskevi Karousi , Julie Courraud , Jérôme Moreaux et al.

International Conference on Molecular Targets and Cancer Therapeutics, American Association for Cancer Research; National Cancer Institute; European Organisation for Research and Treatment of Cancer, Oct 2025, Boston (Massachusetts), United States. ⟨10.1158/1535-7163.TARG-25-C047⟩

Communication dans un congrès hal-05473990v1

Integrative Single-Cell RNA-Seq and Single-Cell ATAC-Seq Analysis of Human Plasma Cell Differentiation

Elina Alaterre , Sara Ovejero , Marion Espéli , Thierry Fest , Michel Cogné et al.

65th Annual Meeting of the American Society of Hematology (ASH 2023), American Society of Hematology (ASH), Dec 2023, San Diego, United States. ⟨10.1182/blood-2023-181507⟩

Communication dans un congrès hal-04513440v1

Une collection unique de cellules viables humaines cryopréservées de patients atteints de lymphomes, une initiative pour accélérer l'innovation et son transfert dans le domaine du lymphome.

E Mollaret , E Gomez , B Nadel , L Baseggio , E Blasco et al.

SFH, 2020, Paris, France

Communication dans un congrès inserm-04827406v1

Alternative splicing complexity results in a very diverse repertoire of circular RNAs in multiple myeloma, as revealed by nanopore sequencing

Maria Papatsirou , Evangelos Terpos , Jérôme Moreaux , Andreas Scorilas , Christos Kontos

49th FEBS Congress, Jul 2025, Istanbul, Turkey. , FEBS OPEN BIO, 15 (Supplement 2), pp.132 / P-16-006, 2025, ⟨10.1002/2211-5463.70071⟩

Poster de conférence hal-05529890v1

Circular RNA Profiling Using High-Accuracy Long-Read Nanopore Sequencing of Multiple Myeloma Cell Lines Reveals the Wide Diversity of the Circular Transcriptome

Maria Papatsirou , Christos Kontos , Ioannis Ntanasis-Stathopoulos , Christina Sotiropoulou , Christine-Ivy Liacos et al.

66th American Society of Hematology Annual Meeting and Exposition (ASH 2024), Dec 2024, San Diego (CA), United States. , Blood, 144 (Supplement 1), pp.3285-3285, 2024, ⟨10.1182/blood-2024-206812⟩

Poster de conférence hal-05528579v1

Early Progressions of Undetermined Significance (EPUS) in the Month Following CAR-T Cells for B-Cell NHL Is Mainly Related to Pseudoprogression

Benoît Tisserand , Caroline Bret , Yassine Al Tabaa , Sylvain Lamure , Xavier Ayrignac et al.

65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.3124-3125, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-185520⟩

Poster de conférence hal-05474613v1

Epigenetic Modifiers MMSET and EZH2 Physically Interact and Cooperate to Support Multiple Myeloma Pathophysiology

Emmanuel Varlet , Elina Alaterre , Morgane Thomas , Hugues de Boussac , Laure Vincent et al.

65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.1964-1965, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181018⟩

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Targeting iron homeostasis in combination with IMiDs as a therapeutic strategy in multiple myeloma

Sara Ovejero , Julie Devin , Tatiana Cañeque , Laura Henry , Laura Alibert et al.

20th International Myeloma Society Annual Meeting (IMS 2023), Sep 2023, Athène, Greece. , Clinical Lymphoma, Myeloma and Leukemia, 23 (Suppl. 2), pp.S149 / P207, 2023, The Abstract from International Myeloma Society 20th Annual Meeting and Exposition

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Translation Inhibition through eIF4A1 Targeting in Multiple Myeloma Is a Promising Therapeutic Strategy

Laure Dutrieux , Elle Loughran , Armelle Choquet , Hélène Herault , Antoine Guillemin et al.

ASH 2023 - 65th ASH Annual Meeting, Dec 2023, San Diego, CA, United States. Elsevier, Blood, 142 (Supplement 1), pp.1924-1925, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-184749⟩

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Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma

Laure Dutrieux , Antoine Guillemin , Yea-Lih Lin , Malik Lutzmann , Guilhem Requirand et al.

20th International Myeloma Society Annual Meeting (IMS 2023), Sep 2023, Athène, Greece. , Clinical Lymphoma, Myeloma and Leukemia, 23 (Suppl. 2), pp.S139 / P188, 2023, The Abstract from International Myeloma Society 20th Annual Meeting and Exposition

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Lipid-Mediated Modulation of DNA Damage Signaling As a Prognostic and Therapeutic Strategy Against Multiple Myeloma

Elvira Garcia de Paco , Caroline Soulet , Guilhem Requirand , Nicolas Robert , Guillaume Cartron et al.

65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Suppl. 1), pp.3322-3322, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181039⟩

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Characterization of a New Metabolic Score Correlated with CD38 Cell-Surface Expression and Response to Daratumumab Treatment in Multiple Myeloma

Alizée Steer , Elina Alaterre , Djamila Chamlal , Emmanuel Varlet , Amélie Machura et al.

65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.1949-1950, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-180877⟩

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Integrative Multi-Omics Analysis of Tumor-Immune Microenvironment in Multiple Myeloma: Novel Insights and Therapeutic Implications

Elina Alaterre , Nicolas Robert , Guilhem Requirand , Amélie Machura , Hugues de Boussac et al.

65th ASH Annual Meeting (ASH 2023), Dec 2023, San Diego (CA), United States. Elsevier, Blood, 142 (Supplement 1), pp.4743-4743, 2023, The 65th ASH Annual Meeting Abstracts. ⟨10.1182/blood-2023-181767⟩

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Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction

Sara Ovejero , Laura Alibert , Julie Devin , Tatiana Cañeque , Ouissem Karmous Gadacha et al.

64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Suppl. 1), pp.6439-6440, 2022, ⟨10.1182/blood-2022-164644⟩

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Development of a Robust BH3 Profiling Toolkit for Precision Medicine in Hematologic Malignancies

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64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Supplement 1), pp.10727-10728, 2022, ⟨10.1182/blood-2022-163207⟩

Poster de conférence hal-05518486v1

Targeting iron homeostasis as a therapeutic strategy in multiple myeloma

Sara Ovejero , Julie Devin , Tatiana Cañeque , Laura Alibert , Guilhem Requirand et al.

64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Suppl. 1), pp.9980-9981, 2022, ⟨10.1182/blood-2022-163252⟩

Poster de conférence hal-05495235v1

EZH2 Targeting Induces CD38 Upregulation and Response to Anti-CD38 Antibodies in Multiple Myeloma

Djamila Chemlal , Emmanuel Varlet , Amélie Machura , Guilhem Requirand , Nicolas Robert et al.

64th American Society of Hematology Annual Meeting and Exposition (ASH 2022), Dec 2022, Nouvelle Orléans (LA), United States. , Blood, 140 (Supplement 1), pp.4220-4221, 2022, ⟨10.1182/blood-2022-163261⟩

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Genomic Characterization of in Vitro Acquired-Resistance to Proteasome Inhibitors

Hugues De Boussac , Alboukadel Kassambara , Amélie Machura , Djamila Chemlal , Claire Gourzones et al.

63rd American Society of Hematology Annual Meeting and Exposition (ASH 2021), Dec 2021, Atlanta (GA), United States. , Blood, 138 (Suppl. 1), pp.2651, 2021, Annual Meeting Abstracts. ⟨10.1182/blood-2021-148584⟩

Poster de conférence hal-05520417v1

Exploiting transcription-replication conflicts as a novel therapeutic intervention in multiple myeloma

Laure Dutrieux , Yea-Lih Lin , Malik Lutzmann , Guilhem Requirand , Nicolas Robert et al.

63rd American Society of Hematology Annual Meeting and Exposition (ASH 2021), Dec 2021, Atlanta (GA), United States. , Blood, 138 (Suppl. 1), pp.1582, 2021, Annual Meeting Abstracts. ⟨10.1182/blood-2021-151530⟩

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