| 
        
                                                 
                        
                     
                                    
     | 
        
        
            Targeting Transcription-Replication Conflicts using G-quadruplexes stabilizers in Multiple Myeloma
        
                            
                                                                                                            Laure Dutrieux
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Antoine Guillemin
                                                                ,
                                                                                                                                Leriem Zellagui
                                                                ,
                                                                                                                                Elke de Bruyne
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    lirmm-04919719
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Ironomycin induces mantle cell lymphoma cell death by targeting iron metabolism addiction
        
                            
                                                                                                            Sara Ovejero
                                                                ,
                                                                                                                                Laura Alibert
                                                                ,
                                                                                                                                Julie Devin
                                                                ,
                                                                                                                                Tatiana Cañeque
                                                                ,
                                                                                                                                Valentin Jacquier
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05343829
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            PIM2 inhibition promotes MCL1 dependency in plasma cells involving integrated stress response-driven NOXA expression
        
                            
                                                                                                            Marion Haas
                                                                ,
                                                                                                                                Sabrina Cherfa
                                                                ,
                                                                                                                                Léa Nguyen
                                                                ,
                                                                                                                                Maxence Bourgoin
                                                                ,
                                                                                                                                Gersende Caron
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04883435
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Editing B cells at the IGHA2 gene position provides alternative route to therapeutic IgA production
        
                            
                                                                                                            Marine Cahen
                                                                ,
                                                                                                                                Jenny Leonard
                                                                ,
                                                                                                                                Ophélie Dézé
                                                                ,
                                                                                                                                Laurent Deleurme
                                                                ,
                                                                                                                                Maïwenn Pineau
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05163114
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Targeting transcription-replication conflicts using G-quadruplexes stabilizers in multiple myeloma
        
                            
                                                                                                            Laure Dutrieux
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Antoine Guillemin
                                                                ,
                                                                                                                                Miss Leriem Zellagui
                                                                ,
                                                                                                                                Elke de Bruyne
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05343640
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Transient loss of Polycomb components induces an epigenetic cancer fate
        
                            
                                                                                                            Victoria Parreno
                                                                ,
                                                                                                                                Vincent Loubiere
                                                                ,
                                                                                                                                Bernd Schuettengruber
                                                                ,
                                                                                                                                Lauriane Fritsch
                                                                ,
                                                                                                                                Chetan C. Rawal
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04581411
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            FCGR3A F158V alleles frequency differs in multiple myeloma patients from healthy population
        
                            
                                                                                                            Michaël Constantinides
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Caroline Multrier
                                                                ,
                                                                                                                                Loïs Coënon
                                                                ,
                                                                                                                                Mauricio Campos-Mora
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704594
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Integrative single-cell chromatin and transcriptome analysis of human plasma cell differentiation
        
                            
                                                                                                            Elina Alaterre
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Caroline Bret
                                                                ,
                                                                                                                                Laure Dutrieux
                                                                ,
                                                                                                                                Dassou Sika
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04701434
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            A case of refractory IgG4-related disease successfully treated with daratumumab and lenalidomide
        
                            
                                                                                                            Denis Coulomb
                                                                ,
                                                                                                                                Vanessa Lacheretz-Szablewski
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Anne-Marie Dupuy
                                                                ,
                                                                                                                                Rayane Berrahouane
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704591
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            BHLHE41, a transcriptional repressor involved in physiological processes and tumor development
        
                            
                                                                                                            Caroline Bret
                                                                ,
                                                                                                                                Fabienne Desmots-Loyer
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Thierry Fest
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704590
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            CD38 , CD39 , and BCL2 differentiate disseminated forms of high‐grade B‐cell lymphomas in biological fluids from Burkitt lymphoma and diffuse large B‐cell lymphoma
        
                            
                                                                                                            Pauline Marianini
                                                                ,
                                                                                                                                Vanessa Lacheretz-Szablewski
                                                                ,
                                                                                                                                Marion Almeras
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Caroline Bret
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704587
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Single-hit genome editing optimized for maturation in B cells redirects their specificity toward tumor antigens
        
                            
                                                                                                            Natsuko Ueda
                                                                ,
                                                                                                                                Marine Cahen
                                                                ,
                                                                                                                                Jenny Leonard
                                                                ,
                                                                                                                                Laurent Deleurme
                                                                ,
                                                                                                                                Stéphane Dreano
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04723581
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            MRE11 and TREX1 control senescence by coordinating replication stress and interferon signaling
        
                            
                                                                                                            Hervé Técher
                                                                ,
                                                                                                                                Diyavarshini Gopaul
                                                                ,
                                                                                                                                Jonathan Heuzé
                                                                ,
                                                                                                                                Nail Bouzalmad
                                                                ,
                                                                                                                                Baptiste Leray
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04748159
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Quantitative Integrative Survival Prediction in Multiple Myeloma Patients Treated With Bortezomib-Based Induction, High-Dose Therapy and Autologous Stem Cell Transplantation
        
                            
                                                                                                            Manuela Hummel
                                                                ,
                                                                                                                                Thomas Hielscher
                                                                ,
                                                                                                                                Martina Emde-Rajaratnam
                                                                ,
                                                                                                                                Hans Salwender
                                                                ,
                                                                                                                                Susanne Beck
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704595
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            KDM6A controls immunogenicity in MM
        
                            
                                                                                                            Jerome Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04912732
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            3-O sulfation of syndecan-1 mediated by the sulfotransferase HS3ST3a1 enhances myeloma aggressiveness
        
                            
                                                                                                            L. Baert
                                                                ,
                                                                                                                                B. Manfroi
                                                                ,
                                                                                                                                M. Quintero
                                                                ,
                                                                                                                                O. Chavarria
                                                                ,
                                                                                                                                P.V. Barbon
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04444452
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Editorial: Transcriptional control in normal and malignant B-lymphocytes
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Alexander A. Shtil
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04705020
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Var∣Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data
        
                            
                                                                                                            Mohammad Salma
                                                                ,
                                                                                                                                Elina Alaterre
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Eric Soler
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04705018
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Extreme thrombocytosis with an aggressive evolution harboring a novel variant of calreticulin (CALR) in exon 3
        
                            
                                                                                                            Sarah Bonnet
                                                                ,
                                                                                                                                Serge Carillo
                                                                ,
                                                                                                                                Baptiste Legrand
                                                                ,
                                                                                                                                Barbara Burroni
                                                                ,
                                                                                                                                Thierry Lavabre-Bertrand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04550049
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            EZH2 targeting induces CD38 upregulation and response to anti-CD38 immunotherapies in multiple myeloma
        
                            
                                                                                                            Djamila Chemlal
                                                                ,
                                                                                                                                Emmanuel Varlet
                                                                ,
                                                                                                                                Amelie Machura
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04252294
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Immunophenotypic portrait of leukemia‐associated‐phenotype markers in B acute lymphoblastic leukemia
        
                            
                                                                                                            Emilia Boris
                                                                ,
                                                                                                                                Alexandre Theron
                                                                ,
                                                                                                                                Valentin Montagnon
                                                                ,
                                                                                                                                Nicolas Rouquier
                                                                ,
                                                                                                                                Marion Almeras
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704605
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Combined inhibition of Wee1 and Chk1 as a therapeutic strategy in multiple myeloma
        
                            
                                                                                                            Angélique Bruyer
                                                                ,
                                                                                                                                Laure Dutrieux
                                                                ,
                                                                                                                                Hugues de Boussac
                                                                ,
                                                                                                                                Thibaut Martin
                                                                ,
                                                                                                                                Djamila Chemlal
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04704603
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            miRNA profile at diagnosis predicts treatment outcome in patients with B-chronic lymphocytic leukemia: A FILO study
        
                            
                                                                                                            Isabelle Duroux-Richard
                                                                ,
                                                                                                                                Anne-Laure Gagez
                                                                ,
                                                                                                                                Elina Alaterre
                                                                ,
                                                                                                                                Rémi Letestu
                                                                ,
                                                                                                                                Olfa Khalifa
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03946290
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The BLM helicase is a new therapeutic target in multiple myeloma involved in replication stress survival and drug resistance
        
                            
                                                                                                            Sara Ovejero
                                                                ,
                                                                                                                                Elena Viziteu
                                                                ,
                                                                                                                                Laure Dutrieux
                                                                ,
                                                                                                                                Julie Devin
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                             (data paper)
                    
        
        
            
                
                    hal-04021632
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Comprehensive characterization of the epigenetic landscape in Multiple Myeloma
        
                            
                                                                                                            Elina Alaterre
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Laurie Herviou
                                                                ,
                                                                                                                                Hugues de Boussac
                                                                ,
                                                                                                                                Giorgio Papadopoulos
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03810219
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
        
                            
                                                                                                            Julie Devin
                                                                ,
                                                                                                                                Tatiana Cañeque
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                ,
                                                                                                                                Lucie Mondoulet
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04053839
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            LAIR1, an ITIM-Containing Receptor Involved in Immune Disorders and in Hematological Neoplasms
        
                            
                                                                                                            François van Laethem
                                                                ,
                                                                                                                                Lucie Donaty
                                                                ,
                                                                                                                                Emmanuelle Tchernonog
                                                                ,
                                                                                                                                Vanessa Lacheretz-Szablewski
                                                                ,
                                                                                                                                Jennifer Russello
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03980144
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            PIM2 kinase has a pivotal role in plasmablast generation and plasma cell survival, opening up novel treatment options in myeloma
        
                            
                                                                                                            Marion Haas
                                                                ,
                                                                                                                                Gersende Caron
                                                                ,
                                                                                                                                Fabrice Chatonnet
                                                                ,
                                                                                                                                Stéphane Manenti
                                                                ,
                                                                                                                                Elina Alaterre
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04822853
                                            v2
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The NADPH oxidase NOX2 is a marker of adverse prognosis involved in chemoresistance of acute myeloid leukemias
        
                            
                                                                                                            Rosa Paolillo
                                                                ,
                                                                                                                                Mathias Boulanger
                                                                ,
                                                                                                                                Pierre Gâtel
                                                                ,
                                                                                                                                Ludovic Gabellier
                                                                ,
                                                                                                                                Marion de Toledo
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03759821
                                            v2
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Targeting the β 2 ‐adrenergic receptor increases chemosensitivity in multiple myeloma by induction of apoptosis and modulating cancer cell metabolism
        
                            
                                                                                                            Hatice Satilmis
                                                                ,
                                                                                                                                Emma Verheye
                                                                ,
                                                                                                                                Philip Vlummens
                                                                ,
                                                                                                                                Inge Oudaert
                                                                ,
                                                                                                                                Niels Vandewalle
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04590992
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Targeting Cellular Iron Homeostasis with Ironomycin in Diffuse Large B-cell Lymphoma
        
                            
                                                                                                            Julie Devin
                                                                ,
                                                                                                                                Tatiana Cañeque
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                ,
                                                                                                                                Lucie Mondoulet
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05344096
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study
        
                            
                                                                                                            Anne Laure Gagez
                                                                ,
                                                                                                                                Franciane Paul
                                                                ,
                                                                                                                                Elina Alaterre
                                                                ,
                                                                                                                                Valérie Gouilleux-Gruart
                                                                ,
                                                                                                                                Edouard Tuaillon
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04041296
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Fanny Izard
                                                                ,
                                                                                                                                Ouissem Karmous-Gadacha
                                                                ,
                                                                                                                                Claire Gourzones
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03450559
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Discovery of candidate DNA methylation cancer driver genes
        
                            
                                                                                                            Heng Pan
                                                                ,
                                                                                                                                Loic Renaud
                                                                ,
                                                                                                                                Ronan Chaligne
                                                                ,
                                                                                                                                Johannes Bloehdorn
                                                                ,
                                                                                                                                Eugen Tausch
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243749
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The origin of pre-plasmablastic cells
        
                            
                                                                                                            Jerome Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243758
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            RNA-Sequencing-Based Transcriptomic Score with Prognostic and Theranostic Values in Multiple Myeloma
        
                            
                                                                                                            Elina Alaterre
                                                                ,
                                                                                                                                Veronika Vikova
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Angélique Bruyer
                                                                ,
                                                                                                                                Nicolas Robert
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03639307
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The microenvironment of DLBCL is characterized by noncanonical macrophages recruited by tumor-derived CCL5
        
                            
                                                                                                            Benoît Manfroi
                                                                ,
                                                                                                                                Maria de Grandis
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Sébastien Tabruyn
                                                                ,
                                                                                                                                Jean-François Mayol
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-04444537
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Clinical Correlations of Polycomb Repressive Complex 2 in Different Tumor Types
        
                            
                                                                                                            Maksim Erokhin
                                                                ,
                                                                                                                                Olga Chetverina
                                                                ,
                                                                                                                                Balázs Győrffy
                                                                ,
                                                                                                                                Victor Tatarskiy
                                                                ,
                                                                                                                                Vladic Mogila
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03693300
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
        
                            
                                                                                                            Laure Dutrieux
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                ,
                                                                                                                                Malik Lutzmann
                                                                ,
                                                                                                                                Raphaël Rodriguez
                                                                ,
                                                                                                                                Michel Cogné
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-05344111
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            RNA Sequencing Data-driven Dissection of Human Plasma Cell Differentiation Reveals New Potential Transcription Regulators
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Laurie Herviou
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Coraline Thibaut
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243729
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Transcription/Replication Conflicts in Tumorigenesis and Their Potential Role as Novel Therapeutic Targets in Multiple Myeloma
        
                            
                                                                                                            Laure Dutrieux
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                ,
                                                                                                                                Malik Lutzmann
                                                                ,
                                                                                                                                Raphaël Rodriguez
                                                                ,
                                                                                                                                Michel Cogné
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03365519
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Immunotherapy perspectives in the new era of B-cell editing
        
                            
                                                                                                            Natsuko Ueda
                                                                ,
                                                                                                                                Marine Cahen
                                                                ,
                                                                                                                                Yannic Danger
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Christophe Sirac
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03202338
                                            v1
                                    
            
        
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    | 
        
                                                
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            Angiogenic factors could help us to define patients obtaining complete response with undetectable minimal residual disease in untreated CLL patients treated by FCR: results from the CLL2010FMP, a FILO study
        
                            
                                                                                                            Anne Laure Gagez
                                                                ,
                                                                                                                                Franciane Paul
                                                                ,
                                                                                                                                Elina Alaterre
                                                                ,
                                                                                                                                Valérie Gouilleux-Gruart
                                                                ,
                                                                                                                                Edouard Tuaillon
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03640354
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            G9a/GLP targeting in MM promotes autophagy-associated apoptosis and boosts proteasome inhibitor–mediated cell death
        
                            
                                                                                                            Eva de Smedt
                                                                ,
                                                                                                                                Julie Devin
                                                                ,
                                                                                                                                Catharina Muylaert
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243723
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The hydroxymethylome of multiple myeloma identifies FAM72D as a 1q21 marker linked to proliferation
        
                            
                                                                                                            Fabrice Chatonnet
                                                                ,
                                                                                                                                Amandine Pignarre
                                                                ,
                                                                                                                                Aurelien Serandour
                                                                ,
                                                                                                                                Gersende Caron
                                                                ,
                                                                                                                                Stéphane Avner
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02165596
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Kinome expression profiling to target new therapeutic avenues in multiple myeloma
        
                            
                                                                                                            Hugues de Boussac
                                                                ,
                                                                                                                                Angelique Bruyer
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Anke Maes
                                                                ,
                                                                                                                                Nicolas N. Robert
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02587620
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            A Retrospective Comparison of DLI and gDLI for Post-Transplant Treatment
        
                            
                                                                                                            Sylvain Lamure
                                                                ,
                                                                                                                                Franciane Paul
                                                                ,
                                                                                                                                Anne-Laure Gagez
                                                                ,
                                                                                                                                Jérémy Delage
                                                                ,
                                                                                                                                Laure Vincent
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03203259
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites
        
                            
                                                                                                            J. Basbous
                                                                ,
                                                                                                                                Antoine Aze
                                                                ,
                                                                                                                                Laurent Chaloin
                                                                ,
                                                                                                                                Rana Lebdy
                                                                ,
                                                                                                                                Dana Hodroj
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02556387
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            DNA Repair Expression Profiling to Identify High-Risk Cytogenetically Normal Acute Myeloid Leukemia and Define New Therapeutic Targets
        
                            
                                                                                                            Ludovic Gabellier
                                                                ,
                                                                                                                                Caroline Bret
                                                                ,
                                                                                                                                Guillaume Bossis
                                                                ,
                                                                                                                                Guillaume Cartron
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03014671
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Characterization of immortalized human islet stromal cells reveals a MSC-like profile with pancreatic features
        
                            
                                                                                                            Orianne Villard
                                                                ,
                                                                                                                                Mathieu Armanet
                                                                ,
                                                                                                                                Guilhem Couderc
                                                                ,
                                                                                                                                Claire Bony
                                                                ,
                                                                                                                                Jerome Moreaux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02961501
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Role of Polycomb Complexes in Normal and Malignant Plasma Cells
        
                            
                                                                                                            Emmanuel Varlet
                                                                ,
                                                                                                                                Sara Ovejero
                                                                ,
                                                                                                                                Anne-Marie Martinez
                                                                ,
                                                                                                                                Giacomo Cavalli
                                                                ,
                                                                                                                                Jerome Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243763
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Comprehensive characterization of the mutational landscape in multiple myeloma cell lines reveals potential drivers and pathways associated with tumor progression and drug resistance
        
                            
                                                                                                            Veronika Vikova
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                ,
                                                                                                                                Stephanie Boireau
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02883457
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Overexpression of Claspin and Timeless protects cancer cells from replication stress in a checkpoint-independent manner
        
                            
                                                                                                            Julien Bianco
                                                                ,
                                                                                                                                Valérie Bergoglio
                                                                ,
                                                                                                                                Yea-Lih Lin
                                                                ,
                                                                                                                                Marie-Jeanne Pillaire
                                                                ,
                                                                                                                                Anne-Lyne Schmitz
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02047561
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Maternal embryonic leucine zipper kinase is a novel target for diffuse large B cell lymphoma and mantle cell lymphoma
        
                            
                                                                                                            Anke Maes
                                                                ,
                                                                                                                                Ken Maes
                                                                ,
                                                                                                                                Philip Vlummens
                                                                ,
                                                                                                                                Hendrik de Raeve
                                                                ,
                                                                                                                                Julie Devin
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02542010
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Prospective target assessment and multimodal prediction of survival for personalized and risk-adapted treatment strategies in multiple myeloma in the GMMG-MM5 multicenter trial
        
                            
                                                                                                            Dirk Hose
                                                                ,
                                                                                                                                Susanne Beck
                                                                ,
                                                                                                                                Hans Salwender
                                                                ,
                                                                                                                                Martina Emde
                                                                ,
                                                                                                                                Uta Bertsch
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243769
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Treatment May Be Harmful: Mechanisms/Prediction/Prevention of Drug-Induced DNA Damage and Repair in Multiple Myeloma
        
                            
                                                                                                            Claire Gourzones
                                                                ,
                                                                                                                                Caroline Bret
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02552817
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            EZH2 is overexpressed in transitional preplasmablasts and is involved in human plasma cell differentiation
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Anne-Marie Martinez
                                                                ,
                                                                                                                                Giacomo Cavalli
                                                                ,
                                                                                                                                Jerome Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243777
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Antioxidant Defenses Confer Resistance to High Dose Melphalan in Multiple Myeloma Cells
        
                            
                                                                                                            Claire Gourzones
                                                                ,
                                                                                                                                Céline Bellanger
                                                                ,
                                                                                                                                Sylvain Lamure
                                                                ,
                                                                                                                                Ouissem Karmous Gadacha
                                                                ,
                                                                                                                                Elvira Garcia de Paco
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02870153
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Anticorps anti-CD38 dans le myélome multiple
        
                            
                                                                                                            Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-03243767
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The Anaphase-Promoting Complex/Cyclosome: A New Promising Target in Diffuse Large B-cell Lymphoma and Mantle Cell Lymphoma
        
                            
                                                                                                            Anke Maes
                                                                ,
                                                                                                                                Ken Maes
                                                                ,
                                                                                                                                Hendrik de Raeve
                                                                ,
                                                                                                                                Eva de Smedt
                                                                ,
                                                                                                                                Philip Vlummens
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                 Article dans une revue
                    
        
        
            
                
                    hal-02862214
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            Myeloid-derived suppressor cells induce multiple myeloma cell survival by activating the AMPK pathway
        
                            
                                                                                                            Kim de Veirman
                                                                ,
                                                                                                                                Eline Menu
                                                                ,
                                                                                                                                Ken Maes
                                                                ,
                                                                                                                                Nathan de Beule
                                                                ,
                                                                                                                                Eva de Smedt
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01980419
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Targeting the methyltransferase SETD8 impairs tumor cell survival and overcomes drug resistance independently of p53 status in multiple myeloma
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Fanny Izard
                                                                ,
                                                                                                                                Ouissem Karmous-Gadacha
                                                                ,
                                                                                                                                Claire Gourzones
                                                                ,
                                                                                                                                Celine Bellanger
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02355848
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Phenotypic Characterization of Diffuse Large B-Cell Lymphoma Cells and Prognostic Impact
        
                            
                                                                                                            Julie Devin
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Angelique Bruyer
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Caroline Bret
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02571739
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related ( ATR ) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer
        
                            
                                                                                                            Eve Combès
                                                                ,
                                                                                                                                Augusto Andrade
                                                                ,
                                                                                                                                Diego Tosi
                                                                ,
                                                                                                                                Henri-Alexandre Michaud
                                                                ,
                                                                                                                                Flavie Coquel
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02361669
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Loss of RASSF4 Expression in Multiple Myeloma Promotes RAS-Driven Malignant Progression
        
                            
                                                                                                            Eva de Smedt
                                                                ,
                                                                                                                                Ken Maes
                                                                ,
                                                                                                                                Stefaan Verhulst
                                                                ,
                                                                                                                                Hui Lui
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01864144
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            PRC2 targeting is a therapeutic strategy for EZ score defined high-risk multiple myeloma patients and overcome resistance to IMiDs
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Stéphanie Boireau
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02315111
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            An epigenetic regulator-related score (EpiScore) predicts survival in patients with diffuse large B cell lymphoma and identifies patients who may benefit from epigenetic therapy
        
                            
                                                                                                            Vanessa Szablewski
                                                                ,
                                                                                                                                Caroline Bret
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Julie Devin
                                                                ,
                                                                                                                                Guillaume Cartron
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02345949
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            DNMTi/HDACi combined epigenetic targeted treatment induces reprogramming of myeloma cells in the direction of normal plasma cells
        
                            
                                                                                                            Angelique Bruyer
                                                                ,
                                                                                                                                Ken Maes
                                                                ,
                                                                                                                                Laurie Herviou
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Anja Seckinger
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01792246
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            BrdU incorporation in multiparameter flow cytometry: A new cell cycle assessment approach in multiple myeloma
        
                            
                                                                                                            Guilhem Requirand
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Stéphanie Boireau
                                                                ,
                                                                                                                                Laure Vincent
                                                                ,
                                                                                                                                Anja Seckinger
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02048196
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                
     | 
        
        
            [EZH2 is therapeutic target for personalized treatment in multiple myeloma].
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Giacomo Cavalli
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01904689
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Physiological and druggable skipping of immunoglobulin variable exons in plasma cells
        
                            
                                                                                                            Mohamad Omar Ashi
                                                                ,
                                                                                                                                Nivine Srour
                                                                ,
                                                                                                                                Jean-Marie Lambert
                                                                ,
                                                                                                                                Anne Marchalot
                                                                ,
                                                                                                                                Ophélie Martin
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02048156
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            Automated and simplified identification of normal and abnormal plasma cells in Multiple Myeloma by flow cytometry
        
                            
                                                                                                            Elina Alaterre
                                                                ,
                                                                                                                                Sébastien Raimbault
                                                                ,
                                                                                                                                Jean-Michel Garcia
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01680330
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Characterization of human FCRL4-positive B cells
        
                            
                                                                                                            Michel Jourdan
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Maïlys Cren
                                                                ,
                                                                                                                                Coraline Thibaut
                                                                ,
                                                                                                                                Christophe Duperray
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01560458
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Inhibiting the anaphase promoting complex/cyclosome induces a metaphase arrest and cell death in multiple myeloma cells
        
                            
                                                                                                            S Lub
                                                                ,
                                                                                                                                A Maes
                                                                ,
                                                                                                                                K Maes
                                                                ,
                                                                                                                                K de Veirman
                                                                ,
                                                                                                                                E de Bruyne
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                 Article dans une revue
                    
        
        
            
                
                    hal-01299387
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            RECQ helicases are deregulated in hematological malignancies in association with a prognostic value
        
                            
                                                                                                            Elena Viziteu
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Philippe Pasero
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Jerome Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-01322505
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Chetomin, targeting HIF-1α/p300 complex, exhibits antitumour activity in multiple myeloma
        
                            
                                                                                                            Elena Viziteu
                                                                ,
                                                                                                                                Camille Grandmougin
                                                                ,
                                                                                                                                Harmut Goldschmidt
                                                                ,
                                                                                                                                Anja Seckinger
                                                                ,
                                                                                                                                Dirk Hose
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01284314
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Differential effects of lenalidomide during plasma cell differentiation
        
                            
                                                                                                            Michel Jourdan
                                                                ,
                                                                                                                                Maïlys Cren
                                                                ,
                                                                                                                                Peter A Schäfer
                                                                ,
                                                                                                                                Nicolas Robert
                                                                ,
                                                                                                                                Christophe Duperray
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01355076
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            EZH2 in normal hematopoiesis and hematological malignancies
        
                            
                                                                                                            Laurie Herviou
                                                                ,
                                                                                                                                Giacomo Cavalli
                                                                ,
                                                                                                                                Guillaume Cartron
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01275235
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Factors influencing extramedullary relapse after allogeneic transplantation for multiple myeloma
        
                            
                                                                                                            L. Vincent
                                                                ,
                                                                                                                                P. Ceballos
                                                                ,
                                                                                                                                Carine Plassot
                                                                ,
                                                                                                                                J. C. Méniane
                                                                ,
                                                                                                                                P. Quittet
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                    hal-01955536
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Drug metabolism and clearance system in tumor cells of patients with multiple myeloma
        
                            
                                                                                                            Wafa Hassen
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                S Sahota
                                                                ,
                                                                                                                                A Seckinger
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                 Article dans une revue
                    
        
        
            
                
                    hal-01153138
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            miRNAs in multiple myeloma - a survival relevant complex regulator of gene expression
        
                            
                                                                                                            A Seckinger
                                                                ,
                                                                                                                                T Meissner
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                V. Benes
                                                                ,
                                                                                                                                J Hillengass
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01237028
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Expression and role of RIP140/NRIP1 in chronic lymphocytic leukemia
        
                            
                                                                                                            Marion Lapierre
                                                                ,
                                                                                                                                Audrey Castet-Nicolas
                                                                ,
                                                                                                                                Delphine Gitenay
                                                                ,
                                                                                                                                Stéphan Jalaguier
                                                                ,
                                                                                                                                Catherine Teyssier
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01153157
                                            v1
                                    
            
        
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    | 
        
                                                 
                        
                     
                                    
     | 
        
        
            DNA repair in diffuse large B-cell lymphoma: a molecular portrait
        
                            
                                                                                                            Caroline Bret
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Guillaume Cartron
                                                                ,
                                                                                                                                Jean-François Schved
                                                                ,
                                                                                                                                Angelos Constantinou
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01143993
                                            v1
                                    
            
        
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            The 7p15.3 (rs4487645) association for multiple myeloma shows strong allele-specific regulation of the MYC-interacting gene CDCA7L in malignant plasma cells
        
                            
                                                                                                            Niels Weinhold
                                                                ,
                                                                                                                                Tobias Meissner
                                                                ,
                                                                                                                                David Johnson
                                                                ,
                                                                                                                                Anja Seckinger
                                                                ,
                                                                                                                                Jerome Moreaux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-02157564
                                            v1
                                    
            
        
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            A DNA repair pathway score predicts survival in human multiple myeloma: the potential for therapeutic strategy
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Claire Gourzones
                                                                ,
                                                                                                                                S. Sahota
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    hal-01006634
                                            v1
                                    
            
        
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            DNA methylation score is predictive of myeloma cell sensitivity to 5-azacitidine.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Angelique Bruyer
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                Hartmut Goldschmidt
                                                                ,
                                                                                                                                Dirk Hose
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00906054
                                            v1
                                    
            
        
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            Identification of a 20-gene expression-based risk score as a predictor of clinical outcome in chronic lymphocytic leukemia patients.
        
                            
                                                                                                            Elias Bou Samra
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Thérèse Commes
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-01023921
                                            v1
                                    
            
        
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            Nucleotide excision DNA repair pathway as a therapeutic target in patients with high-risk diffuse large B cell lymphoma.
        
                            
                                                                                                            Caroline Bret
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00840265
                                            v1
                                    
            
        
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     | 
        
        
            Inhibition of DEPDC1A, a bad prognostic marker in multiple myeloma, delays growth and induces mature plasma cell markers in malignant plasma cells.
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Matthieu Schoenhals
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                Thierry Rème
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00840268
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Gene expression-based prediction of myeloma cell sensitivity to histone deacetylase inhibitors.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Wim Leonard
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00906782
                                            v1
                                    
            
        
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            Genes with a spike expression are clustered in chromosome (sub)bands and spike (sub)bands have a powerful prognostic value in patients with multiple myeloma.
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Brian A. Walker
                                                                ,
                                                                                                                                Alexei Protopopov
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00727008
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Development of gene expression-based risk score in cytogenetically normal acute myeloid leukemia patients.
        
                            
                                                                                                            Elias Bou Samra
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Thérèse Commes
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            Oncotarget, 2012, 3 (8), pp.824-32 
                 Article dans une revue
                    
        
        
            
                
                    inserm-00726665
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            Identification of pluripotent and adult stem cell genes unrelated to cell cycle and associated with poor prognosis in multiple myeloma.
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Jennifer Torrent
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00802686
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Gene expression-based risk score in diffuse large B-cell lymphoma.
        
                            
                                                                                                            Caroline Bret
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            Oncotarget, 2012, 3 (12), pp.1700-10 
                 Article dans une revue
                    
        
        
            
                
                    inserm-00802570
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            STEAP1 is overexpressed in cancers: A promising therapeutic target.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Bernard Klein
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00760262
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Development of gene expression-based score to predict sensitivity of multiple myeloma cells to DNA methylation inhibitors.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Wim Leonard
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                Guilhem Requirand
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00760269
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Clinical and prognostic role of annexin A2 in multiple myeloma.
        
                            
                                                                                                            Anja Seckinger
                                                                ,
                                                                                                                                Tobias Meiβner
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Daniela Depeweg
                                                                ,
                                                                                                                                Jens Hillengass
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00726994
                                            v1
                                    
            
        
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    | 
        
                            
                    
     | 
        
        
            New prognostic markers, determined using gene expression analyses, reveal two distinct subtypes of chronic myelomonocytic leukaemia patients.
        
                            
                                                                                                            Elias Bou Samra
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Fabienne Vacheret
                                                                ,
                                                                                                                                Ken Mills
                                                                ,
                                                                                                                                Florence Rufflé
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00681007
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Residual malignant and normal plasma cells shortly after high dose melphalan and stem cell transplantation. Highlight of a putative therapeutic window in Multiple Myeloma?
        
                            
                                                                                                            Anouk Caraux
                                                                ,
                                                                                                                                Laure Vincent
                                                                ,
                                                                                                                                Salahedine Bouhya
                                                                ,
                                                                                                                                Philippe Quittet
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                            et al.
                            
                 
                            Oncotarget, 2012, 3 (11), pp.1335-47 
                 Article dans une revue
                    
        
        
            
                
                    inserm-00802665
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            SULFs in human neoplasia: implication as progression and prognosis factors.
        
                            
                                                                                                            Caroline Bret
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Jean-François Schved
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Bernard Klein
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00601153
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Osteoclast-gene expression profiling reveals osteoclast-derived CCR2 chemokines promoting myeloma cell migration.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Philippe Moine
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00906774
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            A high-risk signature for patients with multiple myeloma established from the molecular classification of human myeloma cell lines.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Régis Bataille
                                                                ,
                                                                                                                                Géraldine Descamps
                                                                ,
                                                                                                                                Sophie Maïga
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00550232
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Growth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.
        
                            
                                                                                                            Karène Mahtouk
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Tobias Meissner
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00668220
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            MYEOV is a prognostic factor in multiple myeloma.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Amélie Bonnefond
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Nicolas Robert
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00906769
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Induction of angiogenesis by normal and malignant plasma cells.
        
                            
                                                                                                            Dirk Hose
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Tobias Meissner
                                                                ,
                                                                                                                                Anja Seckinger
                                                                ,
                                                                                                                                Hartmut Goldschmidt
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00401390
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Inhibition of Aurora-kinases for tailored risk adapted treatment of multiple myeloma.
        
                            
                                                                                                            Dirk Hose
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Tobias Meissner
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Anja Seckinger
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00368414
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            APRIL is overexpressed in cancer: link with tumor progression.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                John de Vos
                                                                ,
                                                                                                                                Bernard Klein
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00369505
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Embryonic stem cell markers expression in cancers.
        
                            
                                                                                                            Matthieu Schoenhals
                                                                ,
                                                                                                                                Alboukadel Kassambara
                                                                ,
                                                                                                                                John De Vos
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00367054
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Bone morphogenic protein 6: a member of a novel class of prognostic factors expressed by normal and malignant plasma cells inhibiting proliferation and angiogenesis.
        
                            
                                                                                                            Anja Seckinger
                                                                ,
                                                                                                                                Tobias Meissner
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Hartmut Goldschmidt
                                                                ,
                                                                                                                                Gwenny M. Fuhler
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00437705
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The role of IGF-1 as a major growth factor for myeloma cell lines and the prognostic relevance of the expression of its receptor.
        
                            
                                                                                                            Anne Catherine Sprynski
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Laurent Caillot
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                John D. Shaughnessy Jr
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00367812
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            APRIL and TACI interact with syndecan-1 on the surface of multiple myeloma cells to form an essential survival loop.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Anne-Catherine Sprynski
                                                                ,
                                                                                                                                Stacey R. Dillon
                                                                ,
                                                                                                                                Karène Mahtouk
                                                                ,
                                                                                                                                Michel Jourdan
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00397249
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            CD200: a putative therapeutic target in cancer.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Jean-Luc Veyrune
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                John de Vos
                                                                ,
                                                                                                                                Bernard Klein
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00195258
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            MMSET is overexpressed in cancers: Link with tumor aggressiveness.
        
                            
                                                                                                            Alboukadel Kassambara
                                                                ,
                                                                                                                                Bernard Klein
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                    
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00356253
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Targeting NF-kappaB pathway with an IKK2 inhibitor induces inhibition of multiple myeloma cell growth.
        
                            
                                                                                                            Michel Jourdan
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                John De Vos
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Karène Mahtouk
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00160647
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Input of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications.
        
                            
                                                                                                            Karène Mahtouk
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                John de Vos
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                ,
                                                                                                                                Michel Jourdan
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00270566
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            TACI expression is associated with a mature bone marrow plasma cell signature and C-MAF overexpression in human myeloma cell lines.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Michael Hundemer
                                                                                            et al.
                            
                 
                            Haematologica, 2007, 92 (6), pp.803-11 
                 Article dans une revue
                    
        
        
            
                
                    inserm-00162002
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Microarray-based understanding of normal and malignant plasma cells.
        
                            
                                                                                                            John de Vos
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Karin Tarte
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00149827
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            CD200 is a new prognostic factor in multiple myeloma.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Eric Jourdan
                                                                ,
                                                                                                                                Michael Hundemer
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00130595
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Heparan sulphate proteoglycans are essential for the myeloma cell growth activity of EGF-family ligands in multiple myeloma.
        
                            
                                                                                                            Karène Mahtouk
                                                                ,
                                                                                                                                Friedrich W. Cremer
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Marion Baudard
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00128880
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells.
        
                            
                                                                                                            Karène Mahtouk
                                                                ,
                                                                                                                                Dirk Hose
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                John de Vos
                                                                ,
                                                                                                                                Michel Jourdan
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00130206
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Friedrich W. Cremer
                                                                ,
                                                                                                                                Thierry Rème
                                                                ,
                                                                                                                                Marc Raab
                                                                ,
                                                                                                                                Karene Mahtouk
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00129406
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone.
        
                            
                                                                                                            Jérôme Moreaux
                                                                ,
                                                                                                                                Eric Legouffe
                                                                ,
                                                                                                                                Eric Jourdan
                                                                ,
                                                                                                                                Philippe Quittet
                                                                ,
                                                                                                                                Thierry Rème
                                                                                            et al.
                            
                 
                            
                 Article dans une revue
                    
        
        
            
                
                    inserm-00129502
                                            v1
                                    
            
        
     | 
                                                                                
    | 
        
                            
                    
     | 
        
        
            Survival and proliferation factors of normal and malignant plasma cells.
        
                            
                                                                                                            Bernard Klein
                                                                ,
                                                                                                                                Karin Tarte
                                                                ,
                                                                                                                                Michel Jourdan
                                                                ,
                                                                                                                                Karene Mathouk
                                                                ,
                                                                                                                                Jérôme Moreaux
                                                                                            et al.
                            
                 
                            International Journal of Hematology, 2003, 78 (2), pp.106-13 
                 Article dans une revue
                    
        
        
            
                
                    inserm-00130900
                                            v1
                                    
            
        
     |