|
Design, synthesis, and structure–activity relationship studies of 6 H -benzo[ b ]indeno[1,2- d ]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors
Abdelfattah Faouzi
,
Alexandre Arnaud
,
François Hallé
,
Jean Roussel
,
Mandy Aymard
et al.
Article dans une revue
hal-04961871
v1
|
|
Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2
Christelle Marminon
,
Christian Werner
,
Alexander Gast
,
Lars Herfindal
,
Johana Charles
et al.
Article dans une revue
hal-05002241
v1
|
|
Efficient synthesis, crystallographic study, antimicrobial activity and in silico studies of novel bioactive α-aminophosphonates based on pyridine moiety
Ismahene Grib
,
Malika Berredjem
,
Seif-Eddine Djouad
,
Chahrazed Benzaid
,
Khadidja Otmane Rachedi
et al.
Article dans une revue
hal-04775535
v1
|
|
New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline derivatives: synthesis and biological evaluation as novel anticancer agents by targeting G-quadruplex
Jean Guillon
,
Marc Le Borgne
,
Vittoria Milano
,
Aurore Guédin-Beaurepaire
,
Stéphane Moreau
et al.
Article dans une revue
hal-04390485
v1
|
|
To be or not to be manipulated by our bacteria?
Marina Le Borgne
,
Kézia Sossou-Echavidre
,
Christine Janssen
,
Marc Le Borgne
Article dans une revue
hal-04880866
v1
|
|
Antibody–drug conjugates: prospects for the next generation
Meriem Grairi
,
Marc Le Borgne
Article dans une revue
hal-04880853
v1
|
|
L’Europe révise sa période de transition pour l’usage des alliages dentaires cobalt-chrome
Christine Janssen
,
Marc Le Borgne
,
Brigitte Grosgogeat
Biomatériaux Cliniques Dentaires, 2024, 9 (2), pp.90-91
Article dans une revue
hal-04880822
v1
|
|
Formulation and Investigation of CK2 Inhibitor-Loaded Alginate Microbeads with Different Excipients
Boglárka Papp
,
Marc Le Borgne
,
Florent Perret
,
Christelle Marminon
,
Liza Józsa
et al.
Article dans une revue
hal-04314651
v1
|
|
Drug candidates targeting multidrug resistance in cancer and infections
Marc Le Borgne
,
Pierre Falson
,
Ahcène Boumendjel
Article dans une revue
hal-03972628
v1
|
|
Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design
Laura Goracci
,
Alessandra Nurisso
,
Emile Roussel
,
Basile Pérès
,
Vincent Chaptal
et al.
Article dans une revue
hal-03939266
v1
|
|
Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production
Caroline Bayart
,
Angélique Mularoni
,
Nada Hemmani
,
Soumeya Kerachni
,
Joachim Jose
et al.
Article dans une revue
hal-03718458
v1
|
|
Toxicological Risks of the Cobalt–Chromium Alloys in Dentistry: A Systematic Review
Brigitte Grosgogeat
,
Alina Vaicelyte
,
Rémy Gauthier
,
Christine Janssen
,
Marc Le Borgne
Article dans une revue
hal-03815561
v1
|
|
Improved biological performance of ketoprofen using novel modified halloysite clay nanotubes
Dounia Sid
,
Milad Baitiche
,
Lekhmici Arrar
,
Ferhat Djerboua
,
Riadh Bourzami
et al.
Article dans une revue
hal-03475833
v1
|
|
4,5,7‐trisubstituted indeno[1,2‐ b ]indole inhibits CK2 activity in tumor cells equivalent to CX‐4945 and shows strong anti‐migratory effects
Robin Birus
,
Ehab El‐awaad
,
Laurens Ballentin
,
Faten Alchab
,
Dagmar Aichele
et al.
Article dans une revue
hal-03471998
v1
|
|
Brain safety concerns of nanomedicines: The need for a specific regulatory framework
Bartlomiej Szabat-Iriaka
,
Marc Le Borgne
Article dans une revue
hal-03311532
v1
|
|
Adsorption studies of benzophenone-3 onto clay minerals and organosilicates: Kinetics and modelling
Saddam Charaabi
,
Rafik Absi
,
Anne-Marie Pensé-Lhéritier
,
Marc Le Borgne
,
Samar Issa
Article dans une revue
hal-03088439
v1
|
|
Alliages dentaires cobalt-chrome : compatibilité entre le cadre réglementaire européen et la convention nationale ?
Christine Janssen
,
Alina Vaicelyte
,
Marc Le Borgne
,
Brigitte Grosgogeat
Biomatériaux Cliniques Dentaires, 2021, 6 (1), pp.104-107
Article dans une revue
hal-03475825
v1
|
|
Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor
Ehab El-Awaad
,
Robin Birus
,
Christelle Marminon
,
Zouhair Bouaziz
,
Laurens Ballentin
et al.
Article dans une revue
hal-03311530
v1
|
|
Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion
Abdeslem Bouzina
,
Malika Berredjem
,
Alessio Nocentini
,
Silvia Bua
,
Zouhair Bouaziz
et al.
Article dans une revue
hal-02963341
v1
|
|
Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies
Dounia Sid
,
Milad Baitiche
,
Zineb Elbahri
,
Ferhat Djerboua
,
Mokhtar Boutahala
et al.
Article dans une revue
hal-03161350
v1
|
|
Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2
Nathalie Guragossian
,
Billel Belhani
,
Alexis Moreno
,
Magda Teixeira Nunes
,
Lucia Gonzalez-Lobato
et al.
Article dans une revue
hal-03032952
v1
|
|
Microwave-accelerated multicomponent synthesis and X-ray characterization of novel benzothiadiazinone dioxide derivatives, analogues of Monastrol
Abdeslem Bouzina
,
Malika Berredjem
,
Billel Belhani
,
Sofiane Bouacida
,
Christelle Marminon
et al.
Article dans une revue
hal-03112770
v1
|
|
Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles
Diogo Henrique Kita
,
Nathalie Guragossian
,
Ingrid Fatima Zattoni
,
Vivian Rotuno Moure
,
Fabiane Gomes de Moraes Rego
et al.
Article dans une revue
hal-03126318
v1
|
|
Improved Surface Display of Human Hyal1 and Identification of Testosterone Propionate and Chicoric Acid as New Inhibitors
Isabelle Lengers
,
Fabian Herrmann
,
Marc Le Borgne
,
Joachim Jose
Article dans une revue
hal-02539544
v1
|
|
QSAR Model of Indeno[1,2-b]indole Derivatives and Identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-b]furan-3-carboxamide as a Potent CK2 Inhibitor
Samer Haidar
,
Christelle Marminon
,
Dagmar Aichele
,
Abdelhamid Nacereddine
,
Wael Zeinyeh
et al.
Article dans une revue
hal-02424862
v1
|
|
Fragment Linking Strategies for Structure-Based Drug Design
Alexandre Bancet
,
Claire Raingeval
,
Thierry Lomberget
,
Marc Le Borgne
,
Jean-François Guichou
et al.
Article dans une revue
hal-02909120
v1
|
|
Synthesis of new piperazinyl-pyrrolo[1,2- a ]quinoxaline derivatives as inhibitors of Candida albicans multidrug transporters by a Buchwald–Hartwig cross-coupling reaction
Jean Guillon
,
Shweta Nim
,
Stéphane Moreau
,
Luisa Ronga
,
Solène Savrimoutou
et al.
Article dans une revue
hal-02449065
v1
|
|
Cobalt–Chromium Dental Alloys: Metal Exposures, Toxicological Risks, CMR Classification, and EU Regulatory Framework
Alina Vaicelyte
,
Christine Janssen
,
Marc Le Borgne
,
Brigitte Grosgogeat
Article dans une revue
hal-03088443
v1
|
|
Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols
Nicolas Lebouvier
,
Fabrice Pagniez
,
Young Min Na
,
Da Shi
,
Patricia Pinson
et al.
Article dans une revue
hal-02913479
v2
|
|
Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols
Nicolas Lebouvier
,
Fabrice Pagniez
,
Young Min Na
,
Da Shi
,
Patricia Pinson
et al.
Article dans une revue
hal-03389414
v1
|
|
Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent
Fabrice Pagniez
,
Nicolas Lebouvier
,
Young Min Na
,
Isabelle Ourliac-Garnier
,
Carine Picot
et al.
Article dans une revue
hal-02455791
v2
|
|
1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery
Claire Raingeval
,
Olivier Cala
,
Béatrice Brion
,
Marc Le Borgne
,
Roderick Eliot Hubbard
et al.
Article dans une revue
hal-02188259
v1
|
|
Carbazole scaffolds in cancer therapy: a review from 2012 to 2018
Samar Issa
,
Anthony Prandina
,
Nicolas Bedel
,
Pal Rongved
,
Saïd Yous
et al.
Article dans une revue
hal-02190476
v1
|
|
Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures
Dirk Lindenblatt
,
Anna Nickelsen
,
Violetta M Applegate
,
Jennifer Hochscherf
,
Benedict Witulski
et al.
Article dans une revue
hal-02077897
v1
|
|
Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors
Anthony Prandina
,
Sylvie Radix
,
Marc Le Borgne
,
Lars Petter Jordheim
,
Zineb Bousfiha
et al.
Article dans une revue
hal-02054167
v1
|
|
A comparative adsorption study of benzophenone-3 onto synthesized lipophilic organosilicate, Laponite and montmorillonite
Saddam Charaabi
,
Lucien Tchara
,
Christelle Marminon
,
Zouhair Bouaziz
,
Gérard Holtzinger
et al.
Article dans une revue
hal-02004994
v1
|
|
Behaviour of Tetrabenazine in Acid Medium: Reassessment and Impact on Formulation
Laurent Ettouati
,
Zoé Senta-Loys
,
Sandrine Bourgeois
,
Bernard Fenet
,
Marc Le Borgne
et al.
Article dans une revue
hal-01987081
v1
|
|
Comparison of SEC and AF4 analytical tools for size estimation of typhoid Vi polysaccharides
Caroline Bayart
,
Elisa Jean
,
Marie Paillagot
,
Alexia Renoud
,
Alice Raillard
et al.
Article dans une revue
hal-02288665
v1
|
|
Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors
Geir Kildahl-Andersen
,
Christian Schnaars
,
Anthony Prandina
,
Sylvie Radix
,
Marc Le Borgne
et al.
Article dans une revue
hal-02077900
v1
|
|
2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 2: Structure–based optimization and investigation of effects specific to the allosteric mode of action
Benoît Bestgen
,
Irina Kufareva
,
Weiguang Seetoh
,
Chris Abell
,
Rolf W Hartmann
et al.
Article dans une revue
hal-02004987
v1
|
|
In vitro modulation of multidrug resistance by pregnane steroids and in vivo inhibition of tumour development by 7α-OBz-11α(R)-OTHP-5β-pregnanedione in K562/R7 and H295R cell xenografts
Ghina Alameh
,
Agnès Emptoz-Bonneton
,
Marc Rolland de Ravel
,
Eva Matera
,
Elisabeth Mappus
et al.
Article dans une revue
hal-02077612
v1
|
|
Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors
Irina Kufareva
,
Benoît Bestgen
,
Paul Brear
,
Renaud Prudent
,
Béatrice Laudet
et al.
Article dans une revue
hal-02348673
v1
|
|
2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 1: Identification of an allosteric binding site
Benoît Bestgen
,
Isabelle Krimm
,
Irina Kufareva
,
Ahmed Kamal
,
Wei Guang Seetoh
et al.
Article dans une revue
hal-02004986
v1
|
|
2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action
Benoît Bestgen
,
Irina Kufareva
,
Weiguang Seetoh
,
Chris Abell
,
Rolf Hartmann
et al.
Article dans une revue
hal-02465880
v1
|
|
Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7
Abdelhamid Nacereddine
,
Andre Bollacke
,
Eszter Roka
,
Christelle Marminon
,
Zouhair Bouaziz
et al.
Article dans une revue
hal-01694352
v1
|
|
Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles
Anthony Prandina
,
Lars Herfindal
,
Sylvie Radix
,
Pal Rongved
,
Stein Døskeland
et al.
Article dans une revue
hal-01688994
v1
|
|
Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors
Christian Schnaars
,
Geir Kildahl-Andersen
,
Anthony Prandina
,
Roya Popal
,
Sylvie Large Radix
et al.
Article dans une revue
hal-01844562
v1
|
|
Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds
Sylwia Bloch
,
Bożena Nejman-Faleńczyk
,
Karolina Pierzynowska
,
Ewa Piotrowska
,
Alicja Węgrzyn
et al.
Article dans une revue
hal-01736468
v1
|
|
Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates
Abdeslem Bouzina
,
Khaoula Bechlem
,
Hajira Berredjem
,
Billel Belhani
,
Imène Becheker
et al.
Article dans une revue
hal-01839215
v1
|
|
Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes
Mehdi Bouchouit
,
Sofiane Bouacida
,
Bachir Zouchoune
,
Hocine Merazig
,
Silvia Bua
et al.
Article dans une revue
hal-01839213
v1
|
|
Structure-based design and profiling of novel 17β-HSD14 inhibitors
Florian Braun
,
Nicole Bertoletti
,
Gabriele Möller
,
Jerzy Adamski
,
Martin Frotscher
et al.
Article dans une revue
hal-01801297
v1
|
|
Sequential MCR/Fisher indolization strategy for the construction of polycyclic carbazole derivatives
Esma Lamera
,
Sofiane Bouacida
,
Marc Le Borgne
,
Zouhair Bouaziz
,
Abdelmalek Bouraiou
Article dans une revue
hal-01683348
v1
|
|
Ebisilc® Organosilicate Particles for Innovative Galenic Formulation
Saddam Charaabi
,
Pata-Eting Kougnassoukou Tchara
,
Zouhair Bouaziz
,
Christelle Marminon
,
Gérard Holtzinger
et al.
Annals of Pharmacology and Pharmaceutics, 2017, 2(10), pp.1103
Article dans une revue
hal-01806454
v1
|
|
Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining
Samer Haidar
,
Zouhair Bouaziz
,
Christelle Marminon
,
Tuomo Laitinen
,
Antti Poso
et al.
Pharmaceuticals, 2017, An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2, 10 ((1)8), ⟨10.3390/ph10010008⟩
Article dans une revue
hal-01683291
v1
|
|
Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′
Jennifer Hochscherf
,
Dirk Lindenblatt
,
Benedict Witulski
,
Robin Birus
,
Dagmar Aichele
et al.
Article dans une revue
hal-01683237
v1
|
|
The combined use of analytical tools for exploring tetanus toxin and tetanus toxoid structures
Caroline Bayart
,
Sébastien Peronin
,
Elisa Jean
,
Joseph Paladino
,
Philippe Talaga
et al.
Article dans une revue
hal-01683240
v1
|
|
Sleep Disorders and Therapeutic Management: A Survey in a French Population of Prisoners
Anaïs Goudard
,
Laure Lalande
,
Camille Bertin
,
Marie Sautereau
,
Marc Le Borgne
et al.
Article dans une revue
hal-01683241
v1
|
|
In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface
Benoît Bestgen
,
Zakia Belaid-Choucair
,
Thierry Lomberget
,
Marc Le Borgne
,
Odile Filhol
et al.
Pharmaceuticals, 2017, An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2, 10 ((1)16), ⟨10.3390/ph10010016⟩
Article dans une revue
hal-01683243
v1
|
|
Editorial: An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2
Joachim Jose
,
Marc Le-Borgne
,
Lorenzo Pinna
,
Mathias Montenarh
Article dans une revue
hal-01683242
v1
|
|
DMAP as a new efficient catalyst for the one-pot synthesis of condensed phthalazines
Esma Lamera
,
Sofiane Bouacida
,
Hocine Merazig
,
Aïssa Chibani
,
Marc Le Borgne
et al.
Article dans une revue
hal-01683401
v1
|
|
2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2
Elisabeta Baiceanu
,
Kim-Anh Nguyen
,
Lucia Gonzalez-Lobato
,
Rachad Nasr
,
Hélène Baubichon-Cortay
et al.
Article dans une revue
hal-01683292
v1
|
|
Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light
Faten Alchab
,
Estelle Sibille
,
Laurent Ettouati
,
Emilie Bana
,
Zouhair Bouaziz
et al.
Article dans une revue
hal-01655213
v1
|
|
Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’
Andre Bollacke
,
Christian Nienberg
,
Marc Le Borgne
,
Joachim Jose
Article dans une revue
hal-01683296
v1
|
|
Candidate Molecule Selection Based on In Silico Predicted ADMET Properties of 12 Indenoindole Derivatives
Nathalie Guragossian
,
Gustavo Jabor Gozzi
,
Bruno Fouillet
,
Marie-Paule Gustin
,
Raphaël Terreux
et al.
Article dans une revue
hal-01683399
v1
|
|
Synthesis of New Steroidal Inhibitors of P-Glycoprotein-Mediated Multidrug Resistance and Biological Evaluation on K562/R7 Erythroleukemia Cells
Marc Rolland de Ravel
,
Ghina Alameh
,
Maxime Melikian
,
Zahia Mahiout
,
Agnès Emptoz-Bonneton
et al.
Article dans une revue
hal-01683301
v1
|
|
Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery
Andre Gratz
,
Andre Bollacke
,
Sara Stephan
,
Christian Nienberg
,
Marc Le Borgne
et al.
Article dans une revue
hal-01683300
v1
|
|
Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2
Gustavo Jabor Gozzi
,
Zouhair Bouaziz
,
Evelyn Winter
,
Nathalia Daflon-Yunes
,
Dagmar Aichele
et al.
Article dans une revue
hal-01174925
v1
|
|
Microwave-assisted oxidation of indan-1-ones into ninhydrins
Christelle Marminon
,
Abdelhamid Nacereddine
,
Zouhair Bouaziz
,
Pascal Nebois
,
Joachim Jose
et al.
Article dans une revue
hal-01683347
v1
|
|
Mechanisms of depolymerization and activation of a polysialic acid and its tetramer by hydrogen peroxide
Christophe Neyra
,
Joseph Paladino
,
Marc Le Borgne
Article dans une revue
hal-01683316
v1
|
|
Biomimetic synthesis of Tramadol
Florine Lecerf-Schmidt
,
Romain Haudecoeur
,
Basile Peres
,
Marc Ferreira Queiroz
,
Marc Marcourt
et al.
Article dans une revue
hal-01683298
v1
|
|
Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity.
Gustavo Jabor Gozzi
,
Zouhair Bouaziz
,
Evelyn Winter
,
Nathalia Daflon-Yunes
,
Mylène Honorat
et al.
Article dans une revue
hal-01179426
v1
|
|
Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds
Zouhair Bouaziz
,
Samar Issa
,
Jacques Gentili
,
Andre Gratz
,
Andre Bollacke
et al.
Article dans une revue
hal-01683306
v1
|
|
Crystal structure of 13-phenyl-2,3,4,13-tetrahydro-1 H -indazolo[1,2- b ]phthalazine-1,6,11-trione
Esma Lamera
,
Saida Benzerka
,
Abdelmalek Bouraiou
,
Sofiane Bouacida
,
Hocine Merazig
et al.
Acta crystallographica Section E : Crystallographic communications [2015-..], 2015, 71 (12), pp.o1036 - o1037. ⟨10.1107/S2056989015023452⟩
Article dans une revue
hal-01683294
v1
|
|
Synthesis, Biological Evaluation and Molecular Modeling of Substituted Indeno[1,2-b]indoles as Inhibitors of Human Protein Kinase CK2.
Faten Alchab
,
Laurent Ettouati
,
Zouhair Bouaziz
,
Andre Bollacke
,
Jean-Guy Delcros
et al.
Article dans une revue
hal-01164133
v1
|
|
A one-pot three-component synthesis of novel α-sulfamidophosphonates under ultrasound irradiation and catalyst-free conditions
Billel Belhani
,
Malika Berredjem
,
Marc Le Borgne
,
Zouhair Bouaziz
,
Jacques Lebreton
et al.
Article dans une revue
hal-01694993
v1
|
|
Oxidation of sialic acid using hydrogen peroxide as a new method to tune the reducing activity
Christophe Neyra
,
Joseph Paladino
,
Marc Le Borgne
Article dans une revue
hal-01683314
v1
|
|
Structural elucidation of two photolytic degradation products of tetrabenazine
Zouaoui Bourezg
,
Nathalie Cartiser
,
Laurent Ettouati
,
Jean Guillon
,
Aline Lacoudre
et al.
Article dans une revue
hal-01655151
v1
|
|
Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells
Julien Defaux
,
Maud Antoine
,
Cédric Logé
,
Marc Le Borgne
,
Tilmann Schuster
et al.
Article dans une revue
hal-01683305
v1
|
|
Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors
Julien Defaux
,
Maud Antoine
,
Marc Le Borgne
,
Tilmann Schuster
,
Irene Seipelt
et al.
Article dans une revue
istex
hal-01683307
v1
|
|
Preparation and characterization of CK2 inhibitor-loaded cyclodextrin nanoparticles for drug delivery
Florent Perret
,
Christelle Marminon
,
Wael Zeinyeh
,
Pascal Nebois
,
Andre Bollacke
et al.
Article dans une revue
istex
hal-01683336
v1
|
|
Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2
Jean Guillon
,
Marc Le Borgne
,
Charlotte Rimbault
,
Stéphane Moreau
,
Solène Savrimoutou
et al.
Article dans une revue
hal-01683308
v1
|
|
Indenoindoles and cyclopentacarbazoles as bioactive compounds: Synthesis and biological applications
Pal Rongved
,
Gilbert Kirsch
,
Zouhair Bouaziz
,
Joachim Jose
,
Marc Le Borgne
Article dans une revue
istex
hal-01524692
v1
|
|
1H and 13C NMR assignments of bioactive indeno[1,2-b]indole-10-one derivatives
Faten Al Chab
,
Bernard Fenet
,
Marc Le Borgne
,
Joachim Jose
,
Noël Pinaud
et al.
Article dans une revue
istex
hal-01655126
v1
|
|
A safe and practical method for the preparation of 7α-thioether and thioester derivatives of spironolactone
Géraldine Agusti
,
Sandrine Bourgeois
,
Nathalie Cartiser
,
Hatem Fessi
,
Marc Le Borgne
et al.
Article dans une revue
hal-01683309
v1
|
|
Occurrence of the Synthetic Analgesic Tramadol in an African Medicinal Plant.
Ahcène Boumendjel
,
Germain Sotoing Taïwe
,
Elisabeth Ngo Bum
,
Tanguy Chabrol
,
Chantal Beney
et al.
Article dans une revue
istex
inserm-00874145
v1
|
|
African tree gets to the root of pain
Ahcène Boumendjel
,
Germain Sotoing Taïwe
,
Elisabeth Ngo Gum
,
Tanguy Chabrol
,
Chantal Beney
et al.
Article dans une revue
hal-01683403
v1
|
|
Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines
Claas Hundsdörfer
,
Hans-Jörg Hemmerling
,
Janina Hamberger
,
Marc Le Borgne
,
Patrick Bednarski
et al.
Article dans une revue
istex
hal-01683311
v1
|
|
Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors
Claas Hundsdörfer
,
Hans-Jörg Hemmerling
,
Claudia Götz
,
Frank Totzke
,
Patrick Bednarski
et al.
Article dans une revue
istex
hal-01683312
v1
|
|
Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols
Rémi Guillon
,
Fabrice Pagniez
,
Francis Giraud
,
Damien Crépin
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689176
v1
|
|
Design, synthesis and evaluation of 3-(imidazol- 1-ylmethyl)indoles as antileishmanial agents. Part II
Francis Giraud
,
Cédric Logé
,
Fabrice Pagniez
,
Damien Crépin
,
Sophie Barres
et al.
Article dans une revue
hal-01689191
v1
|
|
Synthesis and structure–activity relationships of 2-phenyl-1-[(pyridinyl- and piperidinylmethyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents
Francis Giraud
,
Rémi Guillon
,
Cédric Logé
,
Fabrice Pagniez
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689192
v1
|
|
Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols
Rémi Guillon
,
Francis Giraud
,
Cédric Logé
,
Marc Le Borgne
,
Carine Picot
et al.
Article dans une revue
istex
hal-01689189
v1
|
|
Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents
Francis Giraud
,
Cédric Logé
,
Fabrice Pagniez
,
Damien Crépin
,
Patrice Le Pape
et al.
Article dans une revue
istex
hal-01689196
v1
|
|
Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors
Marie-Pierre Lézé
,
Anja Palusczak
,
Rolf W Hartmann
,
Marc Le Borgne
Article dans une revue
istex
hal-01689195
v1
|
|
Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety
Nicolas Lebouvier
,
Fabrice Pagniez
,
Muriel Duflos
,
Patrice Le Pape
,
Young Min Na
et al.
Article dans une revue
istex
hal-01689197
v1
|
|
Synthesis and biological evaluation of 3-(azolylmethyl)-1 H -indoles and 3-(α-azolylbenzyl)-1 H -indoles as selective aromatase inhibitors
Marc Le Borgne
,
Pascal Marchand
,
Marie-Renée Nourrisson
,
Denis Loquet
,
Martina Palzer
et al.
Article dans une revue
hal-01689199
v1
|
|
A 3D-QSAR CoMSIA study on 3-azolylmethylindoles as anti-leishmanial agents
Francis Giraud
,
Cédric Logé
,
Marc Le Borgne
,
Fabrice Pagniez
,
Young Min Na
et al.
Article dans une revue
hal-01689291
v1
|
|
Efficient microwave-assisted synthesis of 1-(1H-indol-1-yl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents
Nicolas Lebouvier
,
Francis Giraud
,
Typhanie Corbin
,
Young Min Na
,
Guillaume Le Baut
et al.
Article dans une revue
istex
hal-01689208
v1
|
|
Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors
Marie-Pierre Lézé
,
Marc Le Borgne
,
Patricia Pinson
,
Anja Palusczak
,
Muriel Duflos
et al.
Article dans une revue
istex
hal-01689230
v1
|
|
Antileishmanial activities and mechanisms of action of indole-based azoles
Fabrice Pagniez
,
Hiam Abdala-Valencia
,
Pascal Marchand
,
Marc Le Borgne
,
Guillaume Le Baut
et al.
Article dans une revue
hal-01689215
v1
|
|
Three-dimensional model of cytochrome P450 human aromatase
Cédric Logé
,
Marc Le Borgne
,
Pascal Marchand
,
Jean-Michel Robert
,
Guillaume Le Baut
et al.
Article dans une revue
hal-01689233
v1
|
|
2- and 3-[(Aryl)(azolyl)methyl]indoles as Potential Non-steroidal Aromatase Inhibitors
Marie-Pierre Lézé
,
Marc Le Borgne
,
Pascal Marchand
,
Denis Loquet
,
Manuela Kogler
et al.
Article dans une revue
hal-01689238
v1
|
|
Synthesis and Antileishmanial Activity of 3-Imidazolylalkylindoles. Part I
Young Min Na
,
Nicolas Lebouvier
,
Marc Le Borgne
,
Fabrice Pagniez
,
Nidia Alvarez
et al.
Article dans une revue
hal-01689240
v1
|
|
Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives
Young Min Na
,
Marc Le Borgne
,
Fabrice Pagniez
,
Guillaume Le Baut
,
Patrice Le Pape
Article dans une revue
istex
hal-01689264
v1
|
|
Retinoic Acid Metabolism Inhibition by 3-Azolylmethyl-1 H -indoles and 2, 3 or 5-(α-Azolylbenzyl)-1 H -indoles
Marc Le Borgne
,
Pascal Marchand
,
Guillaume Le Baut
,
Masoud Ahmadi
,
H. John Smith
et al.
Article dans une revue
hal-01689267
v1
|
|
Preparation and pharmacological profile of 7-(α-Azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors
Pascal Marchand
,
Marc Le Borgne
,
Martina Palzer
,
Guillaume Le Baut
,
Rolf W Hartmann
Article dans une revue
istex
hal-01689266
v1
|
|
Synthesis and Antileishmanial Activity of 3-(α-Azolylbenzyl)indoles
Pascal Marchand
,
Marc Le Borgne
,
Young Min Na
,
Fabrice Pagniez
,
Hiam Abdala
et al.
Article dans une revue
hal-01689261
v1
|
|
In Vitro Activity of a New Antifungal Azolyl-substituted Indole Against Aspergillus fumigatus
Fabrice Pagniez
,
Marc Le Borgne
,
Pascal Marchand
,
Young Min Na
,
Guillaume Le Baut
et al.
Article dans une revue
hal-01689259
v1
|
|
Potential application of plant lipid transfer proteins for drug delivery
Christine Pato
,
Marc Le Borgne
,
Guillaume Le Baut
,
Patrice Le Pape
,
Didier Marion
et al.
Article dans une revue
istex
hal-01689248
v1
|
|
Dérivés indoliques à activités anti-inflammatoire ou antitumorale
Marc Le Borgne
,
Muriel Duflos
,
Guillaume Le Baut
,
Paul J Nicholls
Annales Pharmaceutiques Françaises, 2000, 58 (5), pp.316 - 320
Article dans une revue
hal-01689246
v1
|
|
New selective nonsteroidal aromatase inhibitors: Synthesis and inhibitory activity of 2,3 or 5-(α-azolylbenzyl)-1H-indoles
Marc Le Borgne
,
Pascal Marchand
,
Bénédicte Delevoye-Seiller
,
Jean-Michel Robert
,
Guillaume Le Baut
et al.
Article dans une revue
istex
hal-01689251
v1
|
|
3-(Azolylmethyl)-1H-indoles as Selective P450 Aromatase Inhibitors
Pascal Marchand
,
Marc Le Borgne
,
Muriel Duflos
,
Sylvie Piessard-Robert
,
Guillaume Le Baut
et al.
Article dans une revue
istex
hal-01689256
v1
|
|
Synthesis andIn Vitro Evaluation of 3-(1-Azolylmethyl)-1H-indoles and 3-(1-Azolyl-1-phenylmethyl)-1H-indoles as Inhibitors of P450 arom
Marc Le Borgne
,
Pascal Marchand
,
Muriel Duflos
,
Bénédicte Delevoye-Seiller
,
Sylvie Piessard-Robert
et al.
Article dans une revue
istex
hal-01689244
v1
|
|
Comparison of the In-vitro Aromatase Inhibitory Activity of 3-(Azolylmethyl)-1H-indoles
Marc Le Borgne
,
Pascal Marchand
,
Muriel Duflos
,
Sylvie Piessard-Robert
,
Guillaume Le Baut
et al.
Article dans une revue
istex
hal-01689254
v1
|