Marc Le Borgne

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Publications

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Design, synthesis, and structure–activity relationship studies of 6 H -benzo[ b ]indeno[1,2- d ]thiophen-6-one derivatives as DYRK1A/CLK1/CLK4/haspin inhibitors

Abdelfattah Faouzi , Alexandre Arnaud , François Hallé , Jean Roussel , Mandy Aymard et al.
RSC Medicinal Chemistry, 2025, 16 (1), pp.179-199. ⟨10.1039/d4md00537f⟩
Article dans une revue hal-04961871 v1
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Exploring the biological potential of the brominated indenoindole MC11 and its interaction with protein kinase CK2

Christelle Marminon , Christian Werner , Alexander Gast , Lars Herfindal , Johana Charles et al.
Biological Chemistry, 2025, ⟨10.1515/hsz-2024-0160⟩
Article dans une revue hal-05002241 v1
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Efficient synthesis, crystallographic study, antimicrobial activity and in silico studies of novel bioactive α-aminophosphonates based on pyridine moiety

Ismahene Grib , Malika Berredjem , Seif-Eddine Djouad , Chahrazed Benzaid , Khadidja Otmane Rachedi et al.
Journal of Molecular Structure, 2024, 1309, pp.138138. ⟨10.1016/j.molstruc.2024.138138⟩
Article dans une revue hal-04775535 v1
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New 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinazoline and 2,4-bis[(substituted-aminomethyl)phenyl]phenylquinoline derivatives: synthesis and biological evaluation as novel anticancer agents by targeting G-quadruplex

Jean Guillon , Marc Le Borgne , Vittoria Milano , Aurore Guédin-Beaurepaire , Stéphane Moreau et al.
Pharmaceuticals, 2024, 17 (1), pp.30. ⟨10.3390/ph17010030⟩
Article dans une revue hal-04390485 v1
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To be or not to be manipulated by our bacteria?

Marina Le Borgne , Kézia Sossou-Echavidre , Christine Janssen , Marc Le Borgne
De Remediis, 2024, 1 (1), pp.25-38. ⟨10.71116/vj4jx563⟩
Article dans une revue hal-04880866 v1
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Antibody–drug conjugates: prospects for the next generation

Meriem Grairi , Marc Le Borgne
Drug Discovery Today, 2024, 29 (12), pp.104241. ⟨10.1016/j.drudis.2024.104241⟩
Article dans une revue hal-04880853 v1

L’Europe révise sa période de transition pour l’usage des alliages dentaires cobalt-chrome

Christine Janssen , Marc Le Borgne , Brigitte Grosgogeat
Biomatériaux Cliniques Dentaires, 2024, 9 (2), pp.90-91
Article dans une revue hal-04880822 v1
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Formulation and Investigation of CK2 Inhibitor-Loaded Alginate Microbeads with Different Excipients

Boglárka Papp , Marc Le Borgne , Florent Perret , Christelle Marminon , Liza Józsa et al.
Pharmaceutics, 2023, Dosage Form Formulation Technologies for Improving Bioavailability, 15 (12), pp.2701. ⟨10.3390/pharmaceutics15122701⟩
Article dans une revue hal-04314651 v1

Drug candidates targeting multidrug resistance in cancer and infections

Marc Le Borgne , Pierre Falson , Ahcène Boumendjel
European Journal of Medicinal Chemistry, 2023, 249, pp.115173. ⟨10.1016/j.ejmech.2023.115173⟩
Article dans une revue hal-03972628 v1
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Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design

Laura Goracci , Alessandra Nurisso , Emile Roussel , Basile Pérès , Vincent Chaptal et al.
European Journal of Medicinal Chemistry, 2023, 248, pp.115070. ⟨10.1016/j.ejmech.2022.115070⟩
Article dans une revue hal-03939266 v1
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Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production

Caroline Bayart , Angélique Mularoni , Nada Hemmani , Soumeya Kerachni , Joachim Jose et al.
Pharmaceuticals, 2022, 15 (6), pp.756. ⟨10.3390/ph15060756⟩
Article dans une revue hal-03718458 v1
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Toxicological Risks of the Cobalt–Chromium Alloys in Dentistry: A Systematic Review

Brigitte Grosgogeat , Alina Vaicelyte , Rémy Gauthier , Christine Janssen , Marc Le Borgne
Materials, 2022, 15 (17), pp.5801. ⟨10.3390/ma15175801⟩
Article dans une revue hal-03815561 v1
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Improved biological performance of ketoprofen using novel modified halloysite clay nanotubes

Dounia Sid , Milad Baitiche , Lekhmici Arrar , Ferhat Djerboua , Riadh Bourzami et al.
Applied Clay Science, 2022, 216, pp.106341. ⟨10.1016/j.clay.2021.106341⟩
Article dans une revue hal-03475833 v1
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4,5,7‐trisubstituted indeno[1,2‐ b ]indole inhibits CK2 activity in tumor cells equivalent to CX‐4945 and shows strong anti‐migratory effects

Robin Birus , Ehab El‐awaad , Laurens Ballentin , Faten Alchab , Dagmar Aichele et al.
FEBS Open Bio, 2022, 12 (2), pp.394-411. ⟨10.1002/2211-5463.13346⟩
Article dans une revue hal-03471998 v1
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Brain safety concerns of nanomedicines: The need for a specific regulatory framework

Bartlomiej Szabat-Iriaka , Marc Le Borgne
Drug Discovery Today, 2021, 26 (11), pp.2502-2507. ⟨10.1016/j.drudis.2021.06.011⟩
Article dans une revue hal-03311532 v1

Adsorption studies of benzophenone-3 onto clay minerals and organosilicates: Kinetics and modelling

Saddam Charaabi , Rafik Absi , Anne-Marie Pensé-Lhéritier , Marc Le Borgne , Samar Issa
Applied Clay Science, 2021, 202, pp.105937. ⟨10.1016/j.clay.2020.105937⟩
Article dans une revue hal-03088439 v1

Alliages dentaires cobalt-chrome : compatibilité entre le cadre réglementaire européen et la convention nationale ?

Christine Janssen , Alina Vaicelyte , Marc Le Borgne , Brigitte Grosgogeat
Biomatériaux Cliniques Dentaires, 2021, 6 (1), pp.104-107
Article dans une revue hal-03475825 v1
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Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Substituted Indeno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor

Ehab El-Awaad , Robin Birus , Christelle Marminon , Zouhair Bouaziz , Laurens Ballentin et al.
Pharmaceuticals, 2021, 14 (6), pp.542. ⟨10.3390/ph14060542⟩
Article dans une revue hal-03311530 v1
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Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion

Abdeslem Bouzina , Malika Berredjem , Alessio Nocentini , Silvia Bua , Zouhair Bouaziz et al.
European Journal of Medicinal Chemistry, 2021, 209, pp.112875. ⟨10.1016/j.ejmech.2020.112875⟩
Article dans une revue hal-02963341 v1
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Solubility enhancement of mefenamic acid by inclusion complex with β-cyclodextrin: in silico modelling, formulation, characterisation, and in vitro studies

Dounia Sid , Milad Baitiche , Zineb Elbahri , Ferhat Djerboua , Mokhtar Boutahala et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36 (1), pp.605-617. ⟨10.1080/14756366.2020.1869225⟩
Article dans une revue hal-03161350 v1
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Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2

Nathalie Guragossian , Billel Belhani , Alexis Moreno , Magda Teixeira Nunes , Lucia Gonzalez-Lobato et al.
European Journal of Medicinal Chemistry, 2021, 211, pp.113017. ⟨10.1016/j.ejmech.2020.113017⟩
Article dans une revue hal-03032952 v1

Microwave-accelerated multicomponent synthesis and X-ray characterization of novel benzothiadiazinone dioxide derivatives, analogues of Monastrol

Abdeslem Bouzina , Malika Berredjem , Billel Belhani , Sofiane Bouacida , Christelle Marminon et al.
Research on Chemical Intermediates, 2021, ⟨10.1007/s11164-020-04378-3⟩
Article dans une revue hal-03112770 v1
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Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles

Diogo Henrique Kita , Nathalie Guragossian , Ingrid Fatima Zattoni , Vivian Rotuno Moure , Fabiane Gomes de Moraes Rego et al.
Scientific Reports, 2021, 11 (1), pp.1788. ⟨10.1038/s41598-020-79892-w⟩
Article dans une revue hal-03126318 v1
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Improved Surface Display of Human Hyal1 and Identification of Testosterone Propionate and Chicoric Acid as New Inhibitors

Isabelle Lengers , Fabian Herrmann , Marc Le Borgne , Joachim Jose
Pharmaceuticals, 2020, 13 (4), pp.54. ⟨10.3390/ph13040054⟩
Article dans une revue hal-02539544 v1
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QSAR Model of Indeno[1,2-b]indole Derivatives and Identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-Dihydronaphtho[2,3-b]furan-3-carboxamide as a Potent CK2 Inhibitor

Samer Haidar , Christelle Marminon , Dagmar Aichele , Abdelhamid Nacereddine , Wael Zeinyeh et al.
Molecules, 2020, 25 (1), pp.97. ⟨10.3390/molecules25010097⟩
Article dans une revue hal-02424862 v1
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Fragment Linking Strategies for Structure-Based Drug Design

Alexandre Bancet , Claire Raingeval , Thierry Lomberget , Marc Le Borgne , Jean-François Guichou et al.
Journal of Medicinal Chemistry, 2020, 63 (20), pp.11420-11435. ⟨10.1021/acs.jmedchem.0c00242⟩
Article dans une revue hal-02909120 v1
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Synthesis of new piperazinyl-pyrrolo[1,2- a ]quinoxaline derivatives as inhibitors of Candida albicans multidrug transporters by a Buchwald–Hartwig cross-coupling reaction

Jean Guillon , Shweta Nim , Stéphane Moreau , Luisa Ronga , Solène Savrimoutou et al.
RSC Advances, 2020, 10 (5), pp.2915-2931. ⟨10.1039/C9RA09348F⟩
Article dans une revue hal-02449065 v1
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Cobalt–Chromium Dental Alloys: Metal Exposures, Toxicological Risks, CMR Classification, and EU Regulatory Framework

Alina Vaicelyte , Christine Janssen , Marc Le Borgne , Brigitte Grosgogeat
Crystals, 2020, 10 (12), pp.1151. ⟨10.3390/cryst10121151⟩
Article dans une revue hal-03088443 v1
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Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Nicolas Lebouvier , Fabrice Pagniez , Young Min Na , Da Shi , Patricia Pinson et al.
Pharmaceuticals, 2020, 13 (8), 186 (32 p.). ⟨10.3390/ph13080186⟩
Article dans une revue hal-02913479 v2
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Synthesis, Optimization, Antifungal Activity, Selectivity, and CYP51 Binding of New 2-Aryl-3-azolyl-1-indolyl-propan-2-ols

Nicolas Lebouvier , Fabrice Pagniez , Young Min Na , Da Shi , Patricia Pinson et al.
Pharmaceuticals, 2020, 13 (8), ⟨10.3390/ph13080186⟩
Article dans une revue hal-03389414 v1
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Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

Fabrice Pagniez , Nicolas Lebouvier , Young Min Na , Isabelle Ourliac-Garnier , Carine Picot et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2020, 35 (1), pp.398-403. ⟨10.1080/14756366.2019.1705292⟩
Article dans une revue hal-02455791 v2
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1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery

Claire Raingeval , Olivier Cala , Béatrice Brion , Marc Le Borgne , Roderick Eliot Hubbard et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1218-1225. ⟨10.1080/14756366.2019.1636235⟩
Article dans une revue hal-02188259 v1
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Carbazole scaffolds in cancer therapy: a review from 2012 to 2018

Samar Issa , Anthony Prandina , Nicolas Bedel , Pal Rongved , Saïd Yous et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.1321-1346. ⟨10.1080/14756366.2019.1640692⟩
Article dans une revue hal-02190476 v1
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Diacritic Binding of an Indenoindole Inhibitor by CK2α Paralogs Explored by a Reliable Path to Atomic Resolution CK2α′ Structures

Dirk Lindenblatt , Anna Nickelsen , Violetta M Applegate , Jennifer Hochscherf , Benedict Witulski et al.
ACS Omega, 2019, 4 (3), pp.5471-5478. ⟨10.1021/acsomega.8b03415⟩
Article dans une revue hal-02077897 v1

Synthesis and biological evaluation of new dipicolylamine zinc chelators as metallo-β-lactamase inhibitors

Anthony Prandina , Sylvie Radix , Marc Le Borgne , Lars Petter Jordheim , Zineb Bousfiha et al.
Tetrahedron, 2019, 75 (11), pp.1525-1540. ⟨10.1016/j.tet.2019.02.004⟩
Article dans une revue hal-02054167 v1

A comparative adsorption study of benzophenone-3 onto synthesized lipophilic organosilicate, Laponite and montmorillonite

Saddam Charaabi , Lucien Tchara , Christelle Marminon , Zouhair Bouaziz , Gérard Holtzinger et al.
Applied Clay Science, 2019, 170, pp.114-124. ⟨10.1016/j.clay.2019.01.005⟩
Article dans une revue hal-02004994 v1
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Behaviour of Tetrabenazine in Acid Medium: Reassessment and Impact on Formulation

Laurent Ettouati , Zoé Senta-Loys , Sandrine Bourgeois , Bernard Fenet , Marc Le Borgne et al.
Pharmaceutics, 2019, 11 (1), pp.44. ⟨10.3390/pharmaceutics11010044⟩
Article dans une revue hal-01987081 v1

Comparison of SEC and AF4 analytical tools for size estimation of typhoid Vi polysaccharides

Caroline Bayart , Elisa Jean , Marie Paillagot , Alexia Renoud , Alice Raillard et al.
Analytical Methods, 2019, ⟨10.1039/C9AY00145J⟩
Article dans une revue hal-02288665 v1

Synthesis and biological evaluation of zinc chelating compounds as metallo-β-lactamase inhibitors

Geir Kildahl-Andersen , Christian Schnaars , Anthony Prandina , Sylvie Radix , Marc Le Borgne et al.
MedChemComm, 2019, 10 (4), pp.528-537. ⟨10.1039/C8MD00578H⟩
Article dans une revue hal-02077900 v1

2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 2: Structure–based optimization and investigation of effects specific to the allosteric mode of action

Benoît Bestgen , Irina Kufareva , Weiguang Seetoh , Chris Abell , Rolf W Hartmann et al.
Journal of Medicinal Chemistry, 2019, 62 (4), pp.1817-1836. ⟨10.1021/acs.jmedchem.8b01765⟩
Article dans une revue hal-02004987 v1
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In vitro modulation of multidrug resistance by pregnane steroids and in vivo inhibition of tumour development by 7α-OBz-11α(R)-OTHP-5β-pregnanedione in K562/R7 and H295R cell xenografts

Ghina Alameh , Agnès Emptoz-Bonneton , Marc Rolland de Ravel , Eva Matera , Elisabeth Mappus et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019, 34 (1), pp.684-691. ⟨10.1080/14756366.2019.1575825⟩
Article dans une revue hal-02077612 v1
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Discovery of holoenzyme-disrupting chemicals as substrate-selective CK2 inhibitors

Irina Kufareva , Benoît Bestgen , Paul Brear , Renaud Prudent , Béatrice Laudet et al.
Scientific Reports, 2019, 9 (1), pp.15893. ⟨10.1038/s41598-019-52141-5⟩
Article dans une revue hal-02348673 v1

2-Aminothiazole derivatives as selective allosteric modulators of the protein kinase CK2. Part 1: Identification of an allosteric binding site

Benoît Bestgen , Isabelle Krimm , Irina Kufareva , Ahmed Kamal , Wei Guang Seetoh et al.
Journal of Medicinal Chemistry, 2019, 62 (4), pp.1803-1816. ⟨10.1021/acs.jmedchem.8b01766⟩
Article dans une revue hal-02004986 v1

2-Aminothiazole Derivatives as Selective Allosteric Modulators of the Protein Kinase CK2. 2. Structure-Based Optimization and Investigation of Effects Specific to the Allosteric Mode of Action

Benoît Bestgen , Irina Kufareva , Weiguang Seetoh , Chris Abell , Rolf Hartmann et al.
Journal of Medicinal Chemistry, 2019, 62 (4), pp.1817-1836. ⟨10.1021/acs.jmedchem.8b01765⟩
Article dans une revue hal-02465880 v1
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Self-Assembled Supramolecular Nanoparticles Improve the Cytotoxic Efficacy of CK2 Inhibitor THN7

Abdelhamid Nacereddine , Andre Bollacke , Eszter Roka , Christelle Marminon , Zouhair Bouaziz et al.
Pharmaceuticals, 2018, 11 ((1)10), ⟨10.3390/ph11010010⟩
Article dans une revue hal-01694352 v1
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Enhancement of iodinin solubility by encapsulation into cyclodextrin nanoparticles

Anthony Prandina , Lars Herfindal , Sylvie Radix , Pal Rongved , Stein Døskeland et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 33 (1), pp.370 - 375. ⟨10.1080/14756366.2017.1421638⟩
Article dans une revue hal-01688994 v1
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Synthesis and preclinical evaluation of TPA-based zinc chelators as metallo-β-lactamase inhibitors

Christian Schnaars , Geir Kildahl-Andersen , Anthony Prandina , Roya Popal , Sylvie Large Radix et al.
ACS Infectious Diseases, 2018, ⟨10.1021/acsinfecdis.8b00137⟩
Article dans une revue hal-01844562 v1
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Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds

Sylwia Bloch , Bożena Nejman-Faleńczyk , Karolina Pierzynowska , Ewa Piotrowska , Alicja Węgrzyn et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 33 (1), pp.639 - 650. ⟨10.1080/14756366.2018.1444610⟩
Article dans une revue hal-01736468 v1
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Synthesis, Spectroscopic Characterization, and In Vitro Antibacterial Evaluation of Novel Functionalized Sulfamidocarbonyloxyphosphonates

Abdeslem Bouzina , Khaoula Bechlem , Hajira Berredjem , Billel Belhani , Imène Becheker et al.
Molecules, 2018, 23 (7), ⟨10.3390/molecules23071682⟩
Article dans une revue hal-01839215 v1
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Synthesis, X-ray structure, in silico calculation, and carbonic anhydrase inhibitory properties of benzylimidazole metal complexes

Mehdi Bouchouit , Sofiane Bouacida , Bachir Zouchoune , Hocine Merazig , Silvia Bua et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2018, 33 (1), pp.1150 - 1159. ⟨10.1080/14756366.2018.1481404⟩
Article dans une revue hal-01839213 v1

Structure-based design and profiling of novel 17β-HSD14 inhibitors

Florian Braun , Nicole Bertoletti , Gabriele Möller , Jerzy Adamski , Martin Frotscher et al.
European Journal of Medicinal Chemistry, 2018, 155, pp.61-76. ⟨10.1016/j.ejmech.2018.05.029⟩
Article dans une revue hal-01801297 v1

Sequential MCR/Fisher indolization strategy for the construction of polycyclic carbazole derivatives

Esma Lamera , Sofiane Bouacida , Marc Le Borgne , Zouhair Bouaziz , Abdelmalek Bouraiou
Tetrahedron Letters, 2017, 58 (13), pp.1305 - 1307. ⟨10.1016/j.tetlet.2017.02.047⟩
Article dans une revue hal-01683348 v1
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Ebisilc® Organosilicate Particles for Innovative Galenic Formulation

Saddam Charaabi , Pata-Eting Kougnassoukou Tchara , Zouhair Bouaziz , Christelle Marminon , Gérard Holtzinger et al.
Annals of Pharmacology and Pharmaceutics, 2017, 2(10), pp.1103
Article dans une revue hal-01806454 v1
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Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Samer Haidar , Zouhair Bouaziz , Christelle Marminon , Tuomo Laitinen , Antti Poso et al.
Pharmaceuticals, 2017, An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2, 10 ((1)8), ⟨10.3390/ph10010008⟩
Article dans une revue hal-01683291 v1
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Unexpected Binding Mode of a Potent Indeno[1,2-b]indole-Type Inhibitor of Protein Kinase CK2 Revealed by Complex Structures with the Catalytic Subunit CK2α and Its Paralog CK2α′

Jennifer Hochscherf , Dirk Lindenblatt , Benedict Witulski , Robin Birus , Dagmar Aichele et al.
Pharmaceuticals, 2017, 10 ((4)98), ⟨10.3390/ph10040098⟩
Article dans une revue hal-01683237 v1

The combined use of analytical tools for exploring tetanus toxin and tetanus toxoid structures

Caroline Bayart , Sébastien Peronin , Elisa Jean , Joseph Paladino , Philippe Talaga et al.
Journal of Chromatography B - Analytical Technologies in the Biomedical and Life Sciences, 2017, 1054, pp.80 - 92. ⟨10.1016/j.jchromb.2017.04.009⟩
Article dans une revue hal-01683240 v1

Sleep Disorders and Therapeutic Management: A Survey in a French Population of Prisoners

Anaïs Goudard , Laure Lalande , Camille Bertin , Marie Sautereau , Marc Le Borgne et al.
Journal of Correctional Health Care, 2017, 23 (2), pp.193 - 202. ⟨10.1177/1078345817700163⟩
Article dans une revue hal-01683241 v1
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In Search of Small Molecule Inhibitors Targeting the Flexible CK2 Subunit Interface

Benoît Bestgen , Zakia Belaid-Choucair , Thierry Lomberget , Marc Le Borgne , Odile Filhol et al.
Pharmaceuticals, 2017, An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2, 10 ((1)16), ⟨10.3390/ph10010016⟩
Article dans une revue hal-01683243 v1
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Editorial: An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2

Joachim Jose , Marc Le-Borgne , Lorenzo Pinna , Mathias Montenarh
Pharmaceuticals, 2017, Pharmaceuticals, 10 ((2)33), pp.33 - 33. ⟨10.3390/ph10020033⟩
Article dans une revue hal-01683242 v1

DMAP as a new efficient catalyst for the one-pot synthesis of condensed phthalazines

Esma Lamera , Sofiane Bouacida , Hocine Merazig , Aïssa Chibani , Marc Le Borgne et al.
Zeitschrift fur Naturforschung B, 2017, 72 ((5)b), pp.361-368. ⟨10.1515/znb-2016-0262⟩
Article dans une revue hal-01683401 v1

2-Indolylmethylenebenzofuranones as first effective inhibitors of ABCC2

Elisabeta Baiceanu , Kim-Anh Nguyen , Lucia Gonzalez-Lobato , Rachad Nasr , Hélène Baubichon-Cortay et al.
European Journal of Medicinal Chemistry, 2016, 122, pp.408 - 418. ⟨10.1016/j.ejmech.2016.06.039⟩
Article dans une revue hal-01683292 v1

Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light

Faten Alchab , Estelle Sibille , Laurent Ettouati , Emilie Bana , Zouhair Bouaziz et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2016, 31 (sup3), pp.25-32. ⟨10.1080/14756366.2016.1201480⟩
Article dans une revue hal-01655213 v1

Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’

Andre Bollacke , Christian Nienberg , Marc Le Borgne , Joachim Jose
Journal of Pharmaceutical and Biomedical Analysis, 2016, 121, pp.253 - 260. ⟨10.1016/j.jpba.2016.01.011⟩
Article dans une revue hal-01683296 v1
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Candidate Molecule Selection Based on In Silico Predicted ADMET Properties of 12 Indenoindole Derivatives

Nathalie Guragossian , Gustavo Jabor Gozzi , Bruno Fouillet , Marie-Paule Gustin , Raphaël Terreux et al.
Chemical Informatics, 2016, 2 ((2)6), ⟨10.21767/2470-6973.100020⟩
Article dans une revue hal-01683399 v1

Synthesis of New Steroidal Inhibitors of P-Glycoprotein-Mediated Multidrug Resistance and Biological Evaluation on K562/R7 Erythroleukemia Cells

Marc Rolland de Ravel , Ghina Alameh , Maxime Melikian , Zahia Mahiout , Agnès Emptoz-Bonneton et al.
Journal of Medicinal Chemistry, 2015, 58 (4), pp.1832 - 1845. ⟨10.1021/jm501676v⟩
Article dans une revue hal-01683301 v1
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Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery

Andre Gratz , Andre Bollacke , Sara Stephan , Christian Nienberg , Marc Le Borgne et al.
Microbial Cell Factories, 2015, 14 (74), ⟨10.1186/s12934-015-0263-z⟩
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Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2

Gustavo Jabor Gozzi , Zouhair Bouaziz , Evelyn Winter , Nathalia Daflon-Yunes , Dagmar Aichele et al.
Journal of Medicinal Chemistry, 2015, 58 (1), pp.265-77. ⟨10.1021/jm500943z⟩
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Microwave-assisted oxidation of indan-1-ones into ninhydrins

Christelle Marminon , Abdelhamid Nacereddine , Zouhair Bouaziz , Pascal Nebois , Joachim Jose et al.
Tetrahedron Letters, 2015, 56 (14), pp.1840 - 1842. ⟨10.1016/j.tetlet.2015.02.086⟩
Article dans une revue hal-01683347 v1

Mechanisms of depolymerization and activation of a polysialic acid and its tetramer by hydrogen peroxide

Christophe Neyra , Joseph Paladino , Marc Le Borgne
Carbohydrate Polymers, 2015, 115, pp.494 - 501. ⟨10.1016/j.carbpol.2014.08.112⟩
Article dans une revue hal-01683316 v1

Biomimetic synthesis of Tramadol

Florine Lecerf-Schmidt , Romain Haudecoeur , Basile Peres , Marc Ferreira Queiroz , Marc Marcourt et al.
Chemical Communications, 2015, 51 (77), pp.14451 - 14453. ⟨10.1039/c5cc05948h⟩
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Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity.

Gustavo Jabor Gozzi , Zouhair Bouaziz , Evelyn Winter , Nathalia Daflon-Yunes , Mylène Honorat et al.
Drug Design, Development and Therapy, 2015, 9, pp.3481-3495. ⟨10.2147/DDDT.S84982⟩
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Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds

Zouhair Bouaziz , Samar Issa , Jacques Gentili , Andre Gratz , Andre Bollacke et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2015, 30 (2), pp.180 - 188. ⟨10.3109/14756366.2014.899594⟩
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Crystal structure of 13-phenyl-2,3,4,13-tetrahydro-1 H -indazolo[1,2- b ]phthalazine-1,6,11-trione

Esma Lamera , Saida Benzerka , Abdelmalek Bouraiou , Sofiane Bouacida , Hocine Merazig et al.
Acta crystallographica Section E : Crystallographic communications [2015-..], 2015, 71 (12), pp.o1036 - o1037. ⟨10.1107/S2056989015023452⟩
Article dans une revue hal-01683294 v1
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Synthesis, Biological Evaluation and Molecular Modeling of Substituted Indeno[1,2-b]indoles as Inhibitors of Human Protein Kinase CK2.

Faten Alchab , Laurent Ettouati , Zouhair Bouaziz , Andre Bollacke , Jean-Guy Delcros et al.
Pharmaceuticals, 2015, 8 (2), pp.279-302. ⟨10.3390/ph8020279⟩
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A one-pot three-component synthesis of novel α-sulfamidophosphonates under ultrasound irradiation and catalyst-free conditions

Billel Belhani , Malika Berredjem , Marc Le Borgne , Zouhair Bouaziz , Jacques Lebreton et al.
RSC Advances, 2015, 5 (49), pp.39324 - 39329. ⟨10.1039/C5RA03473F⟩
Article dans une revue hal-01694993 v1

Oxidation of sialic acid using hydrogen peroxide as a new method to tune the reducing activity

Christophe Neyra , Joseph Paladino , Marc Le Borgne
Carbohydrate Research, 2014, 386, pp.92 - 98. ⟨10.1016/j.carres.2014.01.007⟩
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Structural elucidation of two photolytic degradation products of tetrabenazine

Zouaoui Bourezg , Nathalie Cartiser , Laurent Ettouati , Jean Guillon , Aline Lacoudre et al.
Journal of Pharmaceutical and Biomedical Analysis, 2014, 91, pp.138 - 143. ⟨10.1016/j.jpba.2013.12.032⟩
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Discovery of (7-aryl-1,5-naphthyridin-2-yl)ureas as dual inhibitors of ERK2 and Aurora B kinases with antiproliferative activity against cancer cells

Julien Defaux , Maud Antoine , Cédric Logé , Marc Le Borgne , Tilmann Schuster et al.
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (16), pp.3748 - 3752. ⟨10.1016/j.bmcl.2014.06.078⟩
Article dans une revue hal-01683305 v1

Discovery of 7-Aryl-Substituted (1,5-Naphthyridin-4-yl)ureas as Aurora Kinase Inhibitors

Julien Defaux , Maud Antoine , Marc Le Borgne , Tilmann Schuster , Irene Seipelt et al.
ChemMedChem, 2014, 9 (1), pp.217 - 232. ⟨10.1002/cmdc.201300384⟩
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Preparation and characterization of CK2 inhibitor-loaded cyclodextrin nanoparticles for drug delivery

Florent Perret , Christelle Marminon , Wael Zeinyeh , Pascal Nebois , Andre Bollacke et al.
International Journal of Pharmaceutics, 2013, 441 (1-2), pp.491 - 498. ⟨10.1016/j.ijpharm.2012.11.004⟩
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Synthesis and biological evaluation of novel substituted pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of the human protein kinase CK2

Jean Guillon , Marc Le Borgne , Charlotte Rimbault , Stéphane Moreau , Solène Savrimoutou et al.
European Journal of Medicinal Chemistry, 2013, 65, pp.205 - 222. ⟨10.1016/j.ejmech.2013.04.051⟩
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Indenoindoles and cyclopentacarbazoles as bioactive compounds: Synthesis and biological applications

Pal Rongved , Gilbert Kirsch , Zouhair Bouaziz , Joachim Jose , Marc Le Borgne
European Journal of Medicinal Chemistry, 2013, 69, pp.465 - 479. ⟨10.1016/j.ejmech.2013.08.049⟩
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1H and 13C NMR assignments of bioactive indeno[1,2-b]indole-10-one derivatives

Faten Al Chab , Bernard Fenet , Marc Le Borgne , Joachim Jose , Noël Pinaud et al.
Magnetic Resonance in Chemistry, 2013, 51 (12), pp.837 - 841. ⟨10.1002/mrc.4016⟩
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A safe and practical method for the preparation of 7α-thioether and thioester derivatives of spironolactone

Géraldine Agusti , Sandrine Bourgeois , Nathalie Cartiser , Hatem Fessi , Marc Le Borgne et al.
Steroids, 2013, 78 (1), pp.102 - 107. ⟨10.1016/j.steroids.2012.09.005⟩
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Occurrence of the Synthetic Analgesic Tramadol in an African Medicinal Plant.

Ahcène Boumendjel , Germain Sotoing Taïwe , Elisabeth Ngo Bum , Tanguy Chabrol , Chantal Beney et al.
Angewandte Chemie International Edition, 2013, 52 (45), pp.11780-4. ⟨10.1002/anie.201305697⟩
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African tree gets to the root of pain

Ahcène Boumendjel , Germain Sotoing Taïwe , Elisabeth Ngo Gum , Tanguy Chabrol , Chantal Beney et al.
Nature, 2013, 501 (7467), pp.285 - 285. ⟨10.1038/501285b⟩
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Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines

Claas Hundsdörfer , Hans-Jörg Hemmerling , Janina Hamberger , Marc Le Borgne , Patrick Bednarski et al.
Biochemical and Biophysical Research Communications, 2012, 424 (1), pp.71 - 75. ⟨10.1016/j.bbrc.2012.06.068⟩
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Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors

Claas Hundsdörfer , Hans-Jörg Hemmerling , Claudia Götz , Frank Totzke , Patrick Bednarski et al.
Bioorganic and Medicinal Chemistry, 2012, 20 (7), pp.2282 - 2289. ⟨10.1016/j.bmc.2012.02.017⟩
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Design, Synthesis, and in vitro Antifungal Activity of 1-[(4-Substituted-benzyl)methylamino]-2-(2,4-difluorophenyl)-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Fabrice Pagniez , Francis Giraud , Damien Crépin , Carine Picot et al.
ChemMedChem, 2011, 6 (5), pp.816 - 825. ⟨10.1002/cmdc.201000530⟩
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Design, synthesis and evaluation of 3-(imidazol- 1-ylmethyl)indoles as antileishmanial agents. Part II

Francis Giraud , Cédric Logé , Fabrice Pagniez , Damien Crépin , Sophie Barres et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2009, 24 (5), pp.1067 - 1075. ⟨10.1080/14756360802610795⟩
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Synthesis and structure–activity relationships of 2-phenyl-1-[(pyridinyl- and piperidinylmethyl)amino]-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Francis Giraud , Rémi Guillon , Cédric Logé , Fabrice Pagniez , Carine Picot et al.
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (2), pp.301 - 304. ⟨10.1016/j.bmcl.2008.11.101⟩
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Design of new antifungal agents: synthesis and evaluation of 1-[(1H-indol-5-ylmethyl)amino]-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols

Rémi Guillon , Francis Giraud , Cédric Logé , Marc Le Borgne , Carine Picot et al.
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (20), pp.5833 - 5836. ⟨10.1016/j.bmcl.2009.08.089⟩
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Design, synthesis, and evaluation of 1-(N-benzylamino)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Francis Giraud , Cédric Logé , Fabrice Pagniez , Damien Crépin , Patrice Le Pape et al.
Bioorganic and Medicinal Chemistry Letters, 2008, 18 (6), pp.1820 - 1824. ⟨10.1016/j.bmcl.2008.02.027⟩
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Synthesis of 6- or 4-functionalized indoles via a reductive cyclization approach and evaluation as aromatase inhibitors

Marie-Pierre Lézé , Anja Palusczak , Rolf W Hartmann , Marc Le Borgne
Bioorganic and Medicinal Chemistry Letters, 2008, 18 (16), pp.4713 - 4715. ⟨10.1016/j.bmcl.2008.06.094⟩
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Synthesis and antifungal activities of new fluconazole analogues with azaheterocycle moiety

Nicolas Lebouvier , Fabrice Pagniez , Muriel Duflos , Patrice Le Pape , Young Min Na et al.
Bioorganic and Medicinal Chemistry Letters, 2007, 17 (13), pp.3686 - 3689. ⟨10.1016/j.bmcl.2007.04.038⟩
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Synthesis and biological evaluation of 3-(azolylmethyl)-1 H -indoles and 3-(α-azolylbenzyl)-1 H -indoles as selective aromatase inhibitors

Marc Le Borgne , Pascal Marchand , Marie-Renée Nourrisson , Denis Loquet , Martina Palzer et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2007, 22 (5), pp.667 - 676. ⟨10.1080/14756360701652658⟩
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A 3D-QSAR CoMSIA study on 3-azolylmethylindoles as anti-leishmanial agents

Francis Giraud , Cédric Logé , Marc Le Borgne , Fabrice Pagniez , Young Min Na et al.
SAR and QSAR in Environmental Research, 2006, 17 (3), pp.299 - 309. ⟨10.1080/10659360600787494⟩
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Efficient microwave-assisted synthesis of 1-(1H-indol-1-yl)-2-phenyl-3-(1H-1,2,4-triazol-1-yl)propan-2-ols as antifungal agents

Nicolas Lebouvier , Francis Giraud , Typhanie Corbin , Young Min Na , Guillaume Le Baut et al.
Tetrahedron Letters, 2006, 47 (36), pp.6479 - 6483. ⟨10.1016/j.tetlet.2006.03.199⟩
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Synthesis and biological evaluation of 5-[(aryl)(1H-imidazol-1-yl)methyl]-1H-indoles: Potent and selective aromatase inhibitors

Marie-Pierre Lézé , Marc Le Borgne , Patricia Pinson , Anja Palusczak , Muriel Duflos et al.
Bioorganic and Medicinal Chemistry Letters, 2006, 16 (5), pp.1134 - 1137. ⟨10.1016/j.bmcl.2005.11.099⟩
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Antileishmanial activities and mechanisms of action of indole-based azoles

Fabrice Pagniez , Hiam Abdala-Valencia , Pascal Marchand , Marc Le Borgne , Guillaume Le Baut et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2006, 21 (3), pp.277 - 283. ⟨10.1080/14756360600700517⟩
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Three-dimensional model of cytochrome P450 human aromatase

Cédric Logé , Marc Le Borgne , Pascal Marchand , Jean-Michel Robert , Guillaume Le Baut et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2005, 20 (6), pp.581 - 585. ⟨10.1080/14756360500220574⟩
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2- and 3-[(Aryl)(azolyl)methyl]indoles as Potential Non-steroidal Aromatase Inhibitors

Marie-Pierre Lézé , Marc Le Borgne , Pascal Marchand , Denis Loquet , Manuela Kogler et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2004, 19 (6), pp.549 - 557. ⟨10.1080/14756360400004631⟩
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Synthesis and Antileishmanial Activity of 3-Imidazolylalkylindoles. Part I

Young Min Na , Nicolas Lebouvier , Marc Le Borgne , Fabrice Pagniez , Nidia Alvarez et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2004, 19 (6), pp.451 - 457. ⟨10.1080/14756360412331280509⟩
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Synthesis and antifungal activity of new 1-halogenobenzyl-3-imidazolylmethylindole derivatives

Young Min Na , Marc Le Borgne , Fabrice Pagniez , Guillaume Le Baut , Patrice Le Pape
European Journal of Medicinal Chemistry, 2003, 38 (1), pp.75 - 87. ⟨10.1016/S0223-5234(02)00005-3⟩
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Retinoic Acid Metabolism Inhibition by 3-Azolylmethyl-1 H -indoles and 2, 3 or 5-(α-Azolylbenzyl)-1 H -indoles

Marc Le Borgne , Pascal Marchand , Guillaume Le Baut , Masoud Ahmadi , H. John Smith et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2003, 18 (2), pp.155 - 158. ⟨10.1080/1475636032000069819⟩
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Preparation and pharmacological profile of 7-(α-Azolylbenzyl)-1H-indoles and indolines as new aromatase inhibitors

Pascal Marchand , Marc Le Borgne , Martina Palzer , Guillaume Le Baut , Rolf W Hartmann
Bioorganic and Medicinal Chemistry Letters, 2003, 13 (9), pp.1553 - 1555. ⟨10.1016/S0960-894X(03)00182-3⟩
Article dans une revue istex hal-01689266 v1

Synthesis and Antileishmanial Activity of 3-(α-Azolylbenzyl)indoles

Pascal Marchand , Marc Le Borgne , Young Min Na , Fabrice Pagniez , Hiam Abdala et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2002, 17 (6), pp.353 - 358. ⟨10.1080/1475636021000005613⟩
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In Vitro Activity of a New Antifungal Azolyl-substituted Indole Against Aspergillus fumigatus

Fabrice Pagniez , Marc Le Borgne , Pascal Marchand , Young Min Na , Guillaume Le Baut et al.
Journal of Enzyme Inhibition and Medicinal Chemistry, 2002, 17 (6), pp.425 - 429. ⟨10.1080/1475636021000005686⟩
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Potential application of plant lipid transfer proteins for drug delivery

Christine Pato , Marc Le Borgne , Guillaume Le Baut , Patrice Le Pape , Didier Marion et al.
Biochemical Pharmacology, 2001, 62 (5), pp.555 - 560. ⟨10.1016/S0006-2952(01)00708-0⟩
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Dérivés indoliques à activités anti-inflammatoire ou antitumorale

Marc Le Borgne , Muriel Duflos , Guillaume Le Baut , Paul J Nicholls
Annales Pharmaceutiques Françaises, 2000, 58 (5), pp.316 - 320
Article dans une revue hal-01689246 v1

New selective nonsteroidal aromatase inhibitors: Synthesis and inhibitory activity of 2,3 or 5-(α-azolylbenzyl)-1H-indoles

Marc Le Borgne , Pascal Marchand , Bénédicte Delevoye-Seiller , Jean-Michel Robert , Guillaume Le Baut et al.
Bioorganic and Medicinal Chemistry Letters, 1999, 9 (3), pp.333 - 336. ⟨10.1016/S0960-894X(98)00737-9⟩
Article dans une revue istex hal-01689251 v1

3-(Azolylmethyl)-1H-indoles as Selective P450 Aromatase Inhibitors

Pascal Marchand , Marc Le Borgne , Muriel Duflos , Sylvie Piessard-Robert , Guillaume Le Baut et al.
Pharmacy and Pharmacology Communications, 1998, 4 (4), pp.211 - 218. ⟨10.1111/j.2042-7158.1998.tb00337.x⟩
Article dans une revue istex hal-01689256 v1

Synthesis andIn Vitro Evaluation of 3-(1-Azolylmethyl)-1H-indoles and 3-(1-Azolyl-1-phenylmethyl)-1H-indoles as Inhibitors of P450 arom

Marc Le Borgne , Pascal Marchand , Muriel Duflos , Bénédicte Delevoye-Seiller , Sylvie Piessard-Robert et al.
Archiv der Pharmazie / Chemistry in Life Sciences, 1997, 330 (5), pp.141 - 145. ⟨10.1002/ardp.19973300506⟩
Article dans une revue istex hal-01689244 v1

Comparison of the In-vitro Aromatase Inhibitory Activity of 3-(Azolylmethyl)-1H-indoles

Marc Le Borgne , Pascal Marchand , Muriel Duflos , Sylvie Piessard-Robert , Guillaume Le Baut et al.
Pharmacy and Pharmacology Communications, 1997, 3 (5-6), pp.279 - 281. ⟨10.1111/j.2042-7158.1997.tb00264.x⟩
Article dans une revue istex hal-01689254 v1

The Journey Towards Solubility Assessment of Small Molecules Using HPLC-DAD

Nada Hemmani , Anaïs Cacilie Martin , Andy Larivière , Mathis Tresallet , Kensa Tchang et al.
8th International Electronic Conference on Medicinal Chemistry, Nov 2022, Bâle, Switzerland. ⟨10.3390/ECMC2022-13143⟩
Communication dans un congrès hal-03840347 v2

Biological evaluation of 4,5,7-trisubstituted Indeno[1,2-b]indoles reveals a potent inhibitor of protein kinase CK2 in tumor cells with diverse anti-cancer effects and preferential cytoplasmic localization

Robin Birus , Ehab El-Awaad , Laurens Ballentin , Faten Alchab , Dagmar Aichele et al.
7th International Electronic Conference on Medicinal Chemistry, Nov 2021, Basel, Switzerland. pp.11450, ⟨10.3390/ECMC2021-11450⟩
Communication dans un congrès hal-03552581 v1

Triazole-indole hybrid molecules as antifungal agents: Design, synthesis and biological activity, and beyond

Nicolas Lebouvier , Fabrice Pagniez , Young Min Na , Angélique Mularoni , Marie Brossier et al.
7th International Electronic Conference on Medicinal Chemistry, Nov 2021, Sciforum.net, France. pp.11577, ⟨10.3390/ECMC2021-11577⟩
Communication dans un congrès hal-03556313 v1

Development of water-soluble ternary system for enhancing biological activities of mefenamic acid

Dounia Sid , Milad Baitiche , Zineb Elbahri , Ferhat Djerboua , Mokhtar Boutahala et al.
6th International Electronic Conference on Medicinal Chemistry, Nov 2020, Basel, Switzerland. pp.7461, ⟨10.3390/ECMC2020-07461⟩
Communication dans un congrès hal-03566171 v1

Indeno[1,2-<em>b</em>]indole scaffold in drug discovery: An effective template in kinase inhibitor medicinal chemistry

Robin Birus , Christelle Marminon , Dagmar Aichele , Samer Haidar , Marine Ousset et al.
6th International Electronic Conference on Medicinal Chemistry, Nov 2020, Basel, Switzerland. pp.7433, ⟨10.3390/ECMC2020-07433⟩
Communication dans un congrès hal-03566434 v1

Isoform specific inhibition of human protein kinase CK2α and CK2α’ by an indenoindole derivative

Anna Nickelsen , Dirk Lindenblatt , Violetta Applegate , Jennifer Hochscherf , Benedict Witulski et al.
6th International Electronic Conference on Medicinal Chemistry, Nov 2020, Bâle, Switzerland. pp.7505, ⟨10.3390/ECMC2020-07505⟩
Communication dans un congrès hal-03566145 v1

Design, Synthesis, X-ray Structure and Evaluation of Functionalized Hexacyclic Carbazoles as New Inhibitors of ABCG2 Transporter

Isadora da Silva Zanzarini , Esma Lamera , Sofiane Bouacida , Ingrid Fatima Zattoni , Diogo Henrique Kita et al.
5th International Electronic Conference on Medicinal Chemistry, Nov 2019, Basel, Switzerland
Communication dans un congrès hal-02480387 v1

Investigation of pharmacokinetic properties of CK2 Inhibitors with an Indeno[1,2-b]indole scaffold

Robin Birus , Marc Le Borgne , Joachim Jose
5th International Electronic Conference on Medicinal Chemistry, Nov 2019, Basel, Switzerland
Communication dans un congrès hal-02480385 v1

Indeno[1,2-b]indole Inhibitors of Human Protein Kinase CK2 and Their Impact on Different Tumor Cell Lines (A021)

Dagmar Aichele , Marc Le Borgne , Joachim Jose
Second International Electronic Conference on Medicinal Chemistry (ECMC-2), Nov 2016, Bâle, Switzerland. pp.15/A021, ⟨10.3390/ph10010020⟩
Communication dans un congrès hal-01683452 v1

25th Conference of GP2A

Joachim Jose , Marc Le Borgne , Karsten Niefind
25th Conference of GP2A, Aug 2017, Liverpool, United Kingdom. pp.9-10/2.12, ⟨10.3390/ph10040097⟩
Communication dans un congrès hal-01683410 v1

Development of Pharmacophore Model for Indeno[1,2-b]indoles as Human Protein Kinase CK2 Inhibitors and Database Mining

Samer Haidar , Zouhair Bouaziz , Christelle Marminon , Tiomo Laitinen , Anti Poso et al.
3rd International Electronic Conference on Medicinal Chemistry, Nov 2017, Basel, Switzerland
Communication dans un congrès hal-02480388 v1

Advances in peptidomimetics as inhibitors of ABC transporters

Laurent Ettouati , Marie-Emmanuelle Million , Ophélie Arnaud , Géraldine Agusti , Waël Zeinyeh et al.
1st International Electronic Conference on Medicinal Chemistry, Nov 2015, sciforum.net, France. ⟨10.3390/ecmc-1-A043⟩
Communication dans un congrès hal-01710182 v1