Marie Lopez

36
Documents
Identifiants chercheurs

Présentation

Publications

Publications

3-Halo-3-nitro-aza/thioflavanones: DNMT inhibitors with a two-site binding mode in the hDNMT3A catalytic pocket

Alexandra Serhouni , Francesco Calzaferri , Arie van der Lee , Paola Arimondo , Maxime Louet et al.
Bioorganic and Medicinal Chemistry, 2024, pp.117988. ⟨10.1016/j.bmc.2024.117988⟩
Article dans une revue hal-04817890 v1
Image document

Epidrugs as Promising Tools to Eliminate Plasmodium falciparum Artemisinin-Resistant and Quiescent Parasites

Thibaud Reyser , Lucie Paloque , Michel Nguyen , Jean-Michel Augereau , Matthew John Fuchter et al.
Pharmaceutics, 2023, 15 (10), pp.2440. ⟨10.3390/pharmaceutics15102440⟩
Article dans une revue hal-04269105 v1
Image document

SCF‐ChemBio: Chemical Biology Tour de France

Marie Lopez , Yung‐sing Wong , Christophe Biot , Boris Vauzeilles
ChemBioChem, 2023, ChemBioChem, 24 (10), ⟨10.1002/cbic.202300075⟩
Article dans une revue hal-04199854 v1
Image document

PSL Chemical Biology Symposia Third Edition: A Branch of Science in its Explosive Phase

Leeroy Baron , Justine Hadjerci , Leishemba Thoidingjam , Marina Plays , Romain Bucci et al.
ChemBioChem, 2023, 24 (8), pp.e202300093. ⟨10.1002/cbic.202300093⟩
Article dans une revue hal-04092530 v1
Image document

Unexpected One‐Pot Formation of Lactam Oximes from Amino‐Hydroxamic Esters

Santiago Lascano , Arie van der Lee , Marie Lopez
European Journal of Organic Chemistry, 2022, 2022 (21), ⟨10.1002/ejoc.202200102⟩
Article dans une revue hal-03871396 v1
Image document

Anti-neoplastic and demethylating activity of a newly synthetized flavanone-derived compound in Renal Cell Carcinoma cell lines

Ângela Marques-Magalhães , Inês Graça , Vera Miranda-Gonçalves , Rui Henrique , Marie Lopez et al.
Biomedicine and Pharmacotherapy, 2021, 141, pp.111681. ⟨10.1016/j.biopha.2021.111681⟩
Article dans une revue pasteur-03411793 v1
Image document

Targeting Germ Cell Tumors with the Newly Synthesized Flavanone-Derived Compound MLo1302 Efficiently Reduces Tumor Cell Viability and Induces Apoptosis and Cell Cycle Arrest

João Lobo , Ana Rita Cardoso , Vera Miranda-Gonçalves , Leendert H J Looijenga , Marie Lopez et al.
Pharmaceutics, 2021, Special Issue Cancer Mechanisms and Emerging Therapies, 13 (1), pp.73. ⟨10.3390/pharmaceutics13010073⟩
Article dans une revue pasteur-03105846 v1
Image document

The methylome of Biomphalaria glabrata and other mollusks: enduring modification of epigenetic landscape and phenotypic traits by a new DNA methylation inhibitor

Nelia Luviano , Marie Lopez , Fleur Gawehns , Cristian Chaparro , Paola B Arimondo et al.
Epigenetics & Chromatin, 2021, 14 (1), pp.48. ⟨10.1186/s13072-021-00422-7⟩
Article dans une revue pasteur-03427775 v2
Image document

Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs

Dany Pechalrieu , Fanny Assemat , Ludovic Halby , Marlene Marcellin , Pengrong Yan et al.
ACS Chemical Biology, 2020, 15 (4), pp.952-961. ⟨10.1021/acschembio.9b00965⟩
Article dans une revue pasteur-03026521 v1
Image document

Synthesis of novel 3-halo-3-nitroflavanones and their activities as DNA methyltransferase inhibitors in cancer cells

Dany Pechalrieu , Daniel Dauzonne , Paola Arimondo , Marie Lopez
European Journal of Medicinal Chemistry, 2020, pp.111829. ⟨10.1016/j.ejmech.2019.111829⟩
Article dans une revue hal-02394113 v1
Image document

Natural Products and Chemical Biology Tools: Alternatives to Target Epigenetic Mechanisms in Cancers

Santiago Lascano , Marie Lopez , Paola B Arimondo
Chemical Record, 2018, 18 (12), pp.1854-1876. ⟨10.1002/tcr.201800133⟩
Article dans une revue hal-03082748 v1

Compounds for use in the treatment of mycobacterial infections: a patent evaluation (WO2014049107A1)

Dany Pechalrieu , Marie Lopez
Expert Opinion on Therapeutic Patents, 2015, 25 (6), pp.729-735. ⟨10.1517/13543776.2015.1021333⟩
Article dans une revue hal-02399895 v1

Oxo- and thiooxo-imidazo[1,5-c]pyrimidine molecule library: Beyond their interest in inhibition of Brucella suis histidinol dehydrogenase, a powerful protection tool in the synthesis of histidine analogues

François Turtaut , Marie Lopez , Safia Ouahrani-Bettache , Stephan Köhler , Jean-Yves Winum
Bioorganic and Medicinal Chemistry Letters, 2014, 24 (21), pp.5008-5010. ⟨10.1016/j.bmcl.2014.09.020⟩
Article dans une revue hal-02425098 v1

Synthesis of sulfonamide-conjugated glycosyl-amino acid building blocks

Marie Lopez , Laurent Bornaghi , Sally-Ann Poulsen
Carbohydrate Research, 2014, 386, pp.78-85. ⟨10.1016/j.carres.2013.08.017⟩
Article dans une revue hal-03130488 v1

Structural basis for the rational design of new anti-Brucella agents: The crystal structure of the C366S mutant of l-histidinol dehydrogenase from Brucella suis

Katia d'Ambrosio , Marie Lopez , Nina Dathan , Safia Ouahrani-Bettache , Stephan Köhler et al.
Biochimie, 2014, 97, pp.114-120. ⟨10.1016/j.biochi.2013.09.028⟩
Article dans une revue hal-02425093 v1

Synthesis of acylated glycoconjugates as templates to investigate in vitro biopharmaceutical properties

Cindy Carroux , Janina Moeker , Josephine Motte , Marie Lopez , Laurent Bornaghi et al.
Bioorganic and Medicinal Chemistry Letters, 2013, 23 (2), pp.455-459. ⟨10.1016/j.bmcl.2012.11.056⟩
Article dans une revue hal-03130067 v1

Antimalarial activity of compounds comprising a primary benzene sulfonamide fragment

Katherine Andrews , Gillian Fisher , Subathdrage D.M. Sumanadasa , Tina Skinner-Adams , Janina Moeker et al.
Bioorganic and Medicinal Chemistry Letters, 2013, 23 (22), pp.6114-6117. ⟨10.1016/j.bmcl.2013.09.015⟩
Article dans une revue hal-03130480 v1

Zinc metalloenzymes as new targets against the bacterial pathogen Brucella

Marie Lopez , Stephan Köhler , Jean-Yves Winum
Journal of Inorganic Biochemistry, 2012, 111, pp.138-145. ⟨10.1016/j.jinorgbio.2011.10.019⟩
Article dans une revue istex hal-02424989 v1

Design and synthesis of thiourea compounds that inhibit transmembrane anchored carbonic anhydrases

Janina Moeker , Kanae Teruya , Sabine Rossit , Brendan Wilkinson , Marie Lopez et al.
Bioorganic and Medicinal Chemistry Letters, 2012, 20 (7), pp.2392-2404. ⟨10.1016/j.bmc.2012.01.052⟩
Article dans une revue hal-03130049 v1

Chemo-enzymatic synthesis of xylogluco-oligosaccharides and their interactions with cellulose

Marie Lopez , Sébastien Fort , Herve Bizot , Alain Buléon , Hugues Driguez
Carbohydrate Polymers, 2012, 88 (1), pp.185-193. ⟨10.1016/j.carbpol.2011.11.085⟩
Article dans une revue hal-02119250 v1

Promiscuity of Carbonic Anhydrase II. Unexpected Ester Hydrolysis of Carbohydrate-Based Sulfamate Inhibitors

Marie Lopez , Hoan Vu , Conan Wang , Maarten Wolf , Gerrit Groenhof et al.
Journal of the American Chemical Society, 2011, 133 (45), pp.18452-18462. ⟨10.1021/ja207855c⟩
Article dans une revue hal-03129971 v1

Design, Synthesis, and Biological Evaluation of Novel Carbohydrate-Based Sulfamates as Carbonic Anhydrase Inhibitors

Marie Lopez , Jonathan Trajkovic , Laurent Bornaghi , Alessio Innocenti , Daniela Vullo et al.
Journal of Medicinal Chemistry, 2011, 54 (5), pp.1481-1489. ⟨10.1021/jm101525j⟩
Article dans une revue hal-03129906 v1

Targeting hypoxic tumor cell viability with carbohydrate-based carbonic anhydrase IX and XII inhibitors.

Jason C Morris , Johanna Chiche , Caroline Grellier , Marie Lopez , Laurent F Bornaghi et al.
Journal of Medicinal Chemistry, 2011, 54 (19), pp.6905-18. ⟨10.1021/jm200892s⟩
Article dans une revue hal-00756639 v1

Synthesis of Sulfonamide-Bridged Glycomimetics

Marie Lopez , Laurent Bornaghi , Hugues Driguez , Sally-Ann Poulsen
Journal of Organic Chemistry, 2011, 76 (9), pp.2965-2975. ⟨10.1021/jo2001269⟩
Article dans une revue hal-03129918 v1

Sulfonamide Linked Neoglycoconjugates−A New Class of Inhibitors for Cancer-Associated Carbonic Anhydrases

Marie Lopez , Laurent F Bornaghi , Alessio Innocenti , Daniela Vullo , Susan A. Charman et al.
Journal of Medicinal Chemistry, 2010, 53 (7), pp.2913-2926. ⟨10.1021/jm901888x⟩
Article dans une revue hal-03128749 v1

Synthesis of N-Propargyl Iminosugar Scaffolds for Compound Library Generation using Click Chemistry

Brendan L. Wilkinson , Laurent F Bornaghi , Marie Lopez , Peter C. Healy , Sally-Ann Poulsen et al.
Australian Journal of Chemistry, 2010, 63 (5), pp.821. ⟨10.1071/CH09426⟩
Article dans une revue hal-03129177 v1

Carbonic Anhydrase Inhibitors Developed Through "Click Tailing

Marie Lopez , Adam J. Salmon , Claudiu T. Supuran , Sally-Ann Poulsen
Current Pharmaceutical Design, 2010, 16 (29), pp.3277-3287. ⟨10.2174/138161210793429869⟩
Article dans une revue hal-03129902 v1

Synthesis of S -Glycosyl Primary Sulfonamides

Marie Lopez , Nicolas Drillaud , Laurent F Bornaghi , Sally-Ann Poulsen
Journal of Organic Chemistry, 2009, 74 (7), pp.2811-2816. ⟨10.1021/jo9000367⟩
Article dans une revue hal-03128559 v1

S -Glycosyl Primary Sulfonamides−A New Structural Class for Selective Inhibition of Cancer-Associated Carbonic Anhydrases

Marie Lopez , Blessy Paul , Andreas Hoffmann , Julia Morizzi , Quoc K. Wu et al.
Journal of Medicinal Chemistry, 2009, 52 (20), pp.6421-6432. ⟨10.1021/jm900914e⟩
Article dans une revue hal-03128575 v1

Inhibition of carbonic anhydrase isozymes with benzene sulfonamides incorporating thio, sulfinyl and sulfonyl glycoside moieties

Mathilde Singer , Marie Lopez , Laurent F Bornaghi , Alessio Innocenti , Daniela Vullo et al.
Bioorganic and Medicinal Chemistry Letters, 2009, 19 (8), pp.2273-2276. ⟨10.1016/j.bmcl.2009.02.086⟩
Article dans une revue hal-03128552 v1

The European Sturgeon Acipenser sturio is a suitable host for the glochidia of the freshwater pearl mussel Margaritifera auricularia

Marie Lopez , C.R. Altabla , Thierry Rouault , E. Gisbert
Journal of Molluscan Studies, 2007, 73, pp.207-209
Article dans une revue hal-02589551 v1

Glycosynthase activity of hybrid aspen xyloglucan endo-transglycosylase PttXET16-34 nucleophile mutants.

Kathleen Piens , Anna-Maria Henriksson , Fredrika Gullfot , Marie Lopez , Régis Fauré et al.
Organic & Biomolecular Chemistry, 2007, 5 (24), pp.3971-8. ⟨10.1039/b714570e⟩
Article dans une revue istex hal-00623924 v1
Image document

Inhibitors of DNA Methylation

Marie Lopez , Julie Gilbert , Jean Contreras , Ludovic Halby , Paola B Arimondo
DNA Methyltransferases - Role and Function [Second Edition], 1389, pp.471-513, 2022, Advances in Experimental Medicine and Biology, 978-3-031-11454-0 (eBook). ⟨10.1007/978-3-031-11454-0_17⟩
Chapitre d'ouvrage hal-04269122 v1

Drug Discovery Methods

Marie Lopez , Maxime Leroy , Chantal Etiévant , Frédéric Ausseil , Alexandre Gagnon et al.
Drug Discovery in Cancer Epigenetics, Elsevier, pp.63-95, 2016, ⟨10.1016/b978-0-12-802208-5.00003-5⟩
Chapitre d'ouvrage hal-02399880 v1

DNA Methyltransferase Inhibitors: Development and Applications

Marie Lopez , Ludovic Halby , Paola Arimondo
DNA Methyltransferases - Role and Function, pp.431-473, 2016, ⟨10.1007/978-3-319-43624-1_16⟩
Chapitre d'ouvrage hal-02399858 v1