Nacho MOLINA

28
Documents
Affiliations actuelles
  • Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC)
  • Université de Strasbourg (UNISTRA)
  • Centre National de la Recherche Scientifique (CNRS)
Identifiants chercheurs
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Publications

Publications

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Single-cell multiomics reveals the oscillatory dynamics of mRNA metabolism and chromatin accessibility during the cell cycle

Maulik K Nariya , David Santiago-Algarra , Olivier Tassy , Marie Cerciat , Tao Ye et al.

Cell Reports, 2025, 44 (8), pp.116089. ⟨10.1016/j.celrep.2025.116089⟩

Article dans une revue hal-05461663v2
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Unraveling enteroendocrine cell lineage dynamics and associated gene regulatory networks during intestinal development

Sara Jiménez , Florence Blot , Aline Meunier , Rishabh Kapoor , Valérie Schreiber et al.

Biology Open, 2025, 14 (10), pp.bio062083. ⟨10.1242/bio.062083⟩

Article dans une revue inserm-05324757v2
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Mouse promoters are characterised by low occupancy and high turnover of RNA polymerase II

Kasit Chatsirisupachai , Christina J. I. Moene , Rozemarijn Kleinendorst , Elisa Kreibich , Nacho Molina et al.

Molecular Systems Biology, 2025, 21 (5), pp.447 - 471. ⟨10.1038/s44320-025-00094-5⟩

Article dans une revue hal-05081842v1
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Gene-specific transcript buffering revealed by perturbation of coactivator complexes

Faezeh Forouzanfar , David F Moreno , Damien Plassard , Audrey Furst , Karen Amaral de Oliveira et al.

Science Advances , 2025, 11 (12), pp.eadr1492. ⟨10.1126/sciadv.adr1492⟩

Article dans une revue hal-05001400v2
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Transcription processes compete with loop extrusion to homogenize promoter and enhancer dynamics

Angeliki Platania , Cathie Erb , Mariano Barbieri , Bastien Molcrette , Erwan Grandgirard et al.

Science Advances , 2024, 10 (50), pp.eadq0987. ⟨10.1126/sciadv.adq0987⟩

Article dans une revue hal-04838464v1
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Characterization of cell-fate decision landscapes by estimating transcription factor dynamics

Sara Jiménez , Valérie Schreiber , Reuben Mercier , Gérard Gradwohl , Nacho Molina

Cell Reports Methods, 2023, pp.100512. ⟨10.1016/j.crmeth.2023.100512⟩

Article dans une revue (data paper) inserm-04140681v1
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Cell cycle gene regulation dynamics revealed by RNA velocity and deep-learning

Andrea Riba , Attila Oravecz , Matej Durik , Sara Jiménez , Violaine Alunni et al.

Nature Communications, 2022, 13 (1), pp.2865. ⟨10.1038/s41467-022-30545-8⟩

Article dans une revue hal-03715503v1
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Precise measurements of chromatin diffusion dynamics by modeling using Gaussian processes

Guilherme Oliveira , Attila Oravecz , Dominique Kobi , Manon Maroquenne , Kerstin Bystricky et al.

Nature Communications, 2021, 12 (1), pp.6184. ⟨10.1038/s41467-021-26466-7⟩

Article dans une revue hal-03709399v1
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Molecular Co-occupancy Identifies Transcription Factor Binding Cooperativity In Vivo

Can Sönmezer , Rozemarijn Kleinendorst , Dilek Imanci , Guido Barzaghi , Laura Villacorta et al.

Molecular Cell, 2021, 81 (2), pp.255-267.e6. ⟨10.1016/j.molcel.2020.11.015⟩

Article dans une revue hal-03120499v1
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Regulation of transcription reactivation dynamics exiting mitosis

Sergio Sarnataro , Andrea Riba , Nacho Molina

PLoS Computational Biology, 2021, 17 (10), ⟨10.1371/journal.pcbi.1009354⟩

Article dans une revue hal-03123422v1
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First Responders Shape a Prompt and Sharp NF-κB-Mediated Transcriptional Response to TNF-α

Samuel Zambrano , Alessia Loffreda , Elena Carelli , Giacomo Stefanelli , Federica Colombo et al.

iScience, 2020, 23 (9), pp.101529. ⟨10.1016/j.isci.2020.101529⟩

Article dans une revue hal-03044483v1
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Temporal specificity and heterogeneity of Drosophila immune cells

Pierre Cattenoz , Rosy Sakr , Alexia Pavlidaki , Claude Delaporte , Andrea Riba et al.

EMBO Journal, 2020, 39 (12), ⟨10.15252/embj.2020104486⟩

Article dans une revue hal-02909561v2
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Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

Julie Piccand , Constance Vagne , Florence Blot , Aline Meunier , Anthony Beucher et al.

Molecular metabolism, 2019, 29, pp.24-39. ⟨10.1016/j.molmet.2019.08.007⟩

Article dans une revue hal-02361214v1
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Imaging of native transcription factors and histone phosphorylation at high resolution in live cells

Sascha Conic , Dominique Desplancq , Alexia Ferrand , Véronique Fischer , Vincent Heyer et al.

Journal of Cell Biology, 2018, 217 (4), pp.1537-1552. ⟨10.1083/jcb.201709153⟩

Article dans une revue hal-02349584v1
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Multiple inputs ensure yeast cell size homeostasis during cell cycle progression

Cecilia Garmendia-Torres , Olivier Tassy , Audrey Matifas , Nacho Molina , Gilles Charvin

eLife, 2018, 7, ⟨10.7554/eLife.34025⟩

Article dans une revue hal-02415732v1
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Circadian clock-dependent and -independent posttranscriptional regulation underlies temporal mRNA accumulation in mouse liver

Jingkui Wang , Laura Symul , Jake Yeung , Cédric Gobet , Jonathan Sobel et al.

Proceedings of the National Academy of Sciences of the United States of America, 2018, 115 (8), pp.E1916-E1925. ⟨10.1073/pnas.1715225115⟩

Article dans une revue hal-02415718v1
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Structure of silent transcription intervals and noise characteristics of mammalian genes

Felix Naef , Nacho Molina , Benjamin Zoller , Damien Nicolas

Molecular Systems Biology, 2015, 11 (7), ⟨10.15252/msb.20156257⟩

Article dans une revue hal-05255027v1

Origins and consequences of transcriptional discontinuity

David Suter , Nacho Molina , Felix Naef , Ueli Schibler

Current Opinion in Cell Biology, 2011, 23 (6), pp.657-662. ⟨10.1016/j.ceb.2011.09.004⟩

Article dans une revue istex hal-04064189v1

Mammalian Genes Are Transcribed with Widely Different Bursting Kinetics

David Suter , Nacho Molina , David Gatfield , Kim Schneider , Ueli Schibler et al.

Science, 2011, 332 (6028), pp.472-474. ⟨10.1126/science.1198817⟩

Article dans une revue hal-04028467v1

Scaling laws in functional genome content across prokaryotic clades and lifestyles

Nacho Molina , Erik van Nimwegen

Trends in Genetics, 2009, 25 (6), pp.243-247. ⟨10.1016/j.tig.2009.04.004⟩

Article dans une revue istex hal-04125158v1

Universal patterns of purifying selection at noncoding positions in bacteria

Nacho Molina , Erik van Nimwegen

Genome Research, 2008, 18 (1), pp.148-160. ⟨10.1101/gr.6759507⟩

Article dans une revue hal-04126842v1
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The evolution of domain-content in bacterial genomes

Nacho Molina , Erik van Nimwegen

Biology Direct, 2008, 3 (1), pp.51. ⟨10.1186/1745-6150-3-51⟩

Article dans une revue hal-04126801v1

SwissRegulon: a database of genome-wide annotations of regulatory sites

Mikhail Pachkov , Ionas Erb , Nacho Molina , Erik Van Nimwegen

Nucleic Acids Research, 2007, 35 (Database), pp.D127-D131. ⟨10.1093/nar/gkl857⟩

Article dans une revue hal-04117199v1