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Deep immunophenotyping reveals that autoimmune and autoinflammatory disorders are spread along two immunological axes capturing disease inflammation levels and types
Nicolas Tchitchek
,
Marie Binvignat
,
Alexandra Roux
,
Fabien Pitoiset
,
Johanna Dubois
Article dans une revue
hal-04490369v1
|
|
A randomized double-blind placebo-controlled trial of low-dose interleukin-2 in relapsing–remitting multiple sclerosis
C Louapre
,
M Rosenzwajg
,
M Golse
,
A Roux
,
F Pitoiset
Article dans une revue
hal-04490382v1
|
|
Early systemic inflammation induces neurodevelopmental disorders: results from ARTEMIS, a French multicenter study of juvenile rheumatisms and systemic autoimmune and auto-inflammatory disorders and meta-analysis
Pierre Ellul
,
Isabelle Melki
,
Stephanie Antoun
,
Laura Lavialle
,
Eric Acquaviva
Article dans une revue
hal-03985785v1
|
|
A randomized double-blind placebo-controlled trial of low-dose interleukin-2 in relapsing–remitting multiple sclerosis
C. Louapre
,
M. Rosenzwajg
,
M. Golse
,
A. Roux
,
F. Pitoiset
Article dans une revue
hal-04493282v1
|
|
The Tsallis generalized entropy enhances the interpretation of transcriptomics datasets
Nicolas Dérian
,
Hang-Phuong Pham
,
Djamel Nehar-Belaid
,
Nicolas Tchitchek
,
David Klatzmann
Article dans une revue
hal-03854768v1
|
|
Identification of Symptoms Phenotypes of Hand Osteoarthritis using Hierarchical Clustering: Results from the DIGICOD Cohort
Marie Binvignat
,
Gabriel Pires
,
Nicolas Tchitchek
,
Félicie Costantino
,
Alice Courties
Article dans une revue
hal-03843031v1
|
|
Low-dose IL-2 shapes a tolerogenic gut microbiota that improves autoimmunity and gut inflammation
Nicolas Tchitchek
,
Otriv Nguekap Tchoumba
,
Gabriel Pires
,
Sarah Dandou
,
Julien Campagne
Article dans une revue
hal-03797609v1
|
|
Naive and memory CD4 + T cell subsets can contribute to the generation of human Tfh cells
Raphaël Jeger-Madiot
,
Romain Vaineau
,
Maud Heredia
,
Nicolas Tchitchek
,
Lisa Bertrand
Article dans une revue
hal-03854774v2
|
|
Treatment of COVID-19-associated ARDS with mesenchymal stromal cells: a multicenter randomized double-blind trial
Antoine Monsel
,
Caroline Hauw-Berlemont
,
Miryam Mebarki
,
Nicholas Heming
,
Julien Mayaux
Article dans une revue
hal-03604084v1
|
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Long‐term outcome of paediatric anti‐N‐methyl‐D‐aspartate receptor encephalitis
Lorraine Flet‐berliac
,
Nicolas Tchitchek
,
Anne Lépine
,
Anca Florea
,
Hélène Maurey
Article dans une revue
hal-04490426v1
|
|
The route of vaccine administration determines whether blood neutrophils undergo long-term phenotypic modifications
Yanis Feraoun
,
Jean-Louis Palgen
,
Candie Joly
,
Nicolas Tchitchek
,
Ernesto Marcos-Lopez
Article dans une revue
hal-03787905v1
|
|
Long-term outcome of paediatric anti-N-methyl-D-aspartate receptor encephalitis.
Lorraine Flet-Berliac
,
Nicolas Tchitchek
,
Anne Lépine
,
Anca Florea
,
Hélène Maurey
Article dans une revue
hal-03960996v1
|
|
Bacnet: a user-friendly platform for building multi-omics websites.
Loane Danès
,
Nicolas Tchitchek
,
Christophe Bécavin
Article dans une revue
hal-03961011v1
|
|
Predictive Markers of Immunogenicity and Efficacy for Human Vaccines
Matthieu van Tilbeurgh
,
Katia Lemdani
,
Anne-Sophie Beignon
,
Catherine Chapon
,
Nicolas Tchitchek
Article dans une revue
hal-03278510v1
|
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Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response
Pierre Rosenbaum
,
Nicolas Tchitchek
,
Candie Joly
,
André Rodriguez Pozo
,
Lev Stimmer
Article dans une revue
hal-03321921v1
|
|
Human Ubiquitin-Specific Peptidase 18 Is Regulated by microRNAs via the 3'Untranslated Region, A Sequence Duplicated in Long Intergenic Non-coding RNA Genes Residing in chr22q11.21
Erminia Rubino
,
Melania Cruciani
,
Nicolas Tchitchek
,
Anna Le Tortorec
,
Antoine Rolland
Article dans une revue
hal-03154598v1
|
|
Leukocytospermia induces intraepithelial recruitment of dendritic cells and increases SIV replication in colorectal tissue explants
Mariangela Cavarelli
,
Stéphane Hua
,
Naima Hantour
,
Sabine Tricot
,
Nicolas Tchitchek
Article dans une revue
hal-03287057v1
|
|
Role of NKG2a/c+CD8+ T cells in pathogenic versus non-pathogenic SIV infections
Nicolas Huot
,
Philippe Rascle
,
Nicolas Tchitchek
,
Benedikt Wimmer
,
Caroline Passaes
Article dans une revue
hal-03225293v1
|
|
Low-dose IL-2 in children with recently diagnosed type 1 diabetes: a Phase I/II randomised, double-blind, placebo-controlled, dose-finding study
Michelle Rosenzwajg
,
Randa Salet
,
Roberta Lorenzon
,
Nicolas Tchitchek
,
Alexandra Roux
Article dans une revue
hal-03345047v1
|
|
Interleukin‐7/Interferon axis drives T‐cell and salivary gland epithelial cell interactions in Sjögren’s syndrome
Elodie Rivière
,
Juliette Pascaud
,
Alexandre Virone
,
Anastasia Dupré
,
Bineta Ly
Article dans une revue
pasteur-03036519v1
|
|
Innate and secondary humoral responses are improved by increasing the time between MVA vaccine immunizations
Jean-Louis Palgen
,
Nicolas Tchitchek
,
André Rodriguez-Pozo
,
Quentin Jouhault
,
Hadjer Abdelhouahab
Article dans une revue
hal-03079492v1
|
|
Mechanisms of innate events during skin reaction following intradermal injection of seasonal influenza vaccine
Jessica Gonnet
,
Lauranne Poncelet
,
Celine Meriaux
,
Elena Gonçalves
,
Lina Weiss
Article dans une revue
hal-03984601v2
|
|
Modulation of Cell Surface Receptor Expression by Modified Vaccinia Virus Ankara in Leukocytes of Healthy and HIV-Infected Individuals
Adrien Leite Pereira
,
Quentin Jouhault
,
Ernesto Marcos Lopez
,
Antonio Cosma
,
Olivier Lambotte
Article dans une revue
hal-03960814v1
|
|
Salivary gland epithelial cells from patients with Sjögren's syndrome induce B-lymphocyte survival and activation
Elodie Riviere
,
Juliette Pascaud
,
Nicolas Tchitchek
,
Saida Boudaoud
,
Audrey Paoletti
Article dans une revue
inserm-03150054v1
|
|
Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses After Electroporated DNA Vaccination
Lucille Adam
,
Nicolas Tchitchek
,
Biliana Todorova
,
Pierre Rosenbaum
,
Candie Joly
Article dans une revue
inserm-02869578v1
|
|
Innate Molecular and Cellular Signature in the Skin Preceding Long-Lasting T Cell Responses after Electroporated DNA Vaccination
Lucille Adam
,
Nicolas Tchitchek
,
Biliana Todorova
,
Pierre Rosenbaum
,
Candie Joly
Article dans une revue
hal-03984525v1
|
|
DNA methylation changes in metabolic and immune-regulatory pathways in blood and lymph node CD4 + T cells in response to SIV infections
Simon P. Jochems
,
Beatrice Jacquelin
,
Nicolas Tchitchek
,
Florence Busato
,
Fabien Pichon
Article dans une revue
hal-03225306v1
|
|
Anti-MOG autoantibodies pathogenicity in children and macaques demyelinating diseases
Che Serguera
,
Lev Stimmer
,
Claire-Maëlle Fovet
,
Philippe Horellou
,
Vanessa Contreras
Article dans une revue
cea-02397764v1
|
|
Dynamics of Vaginal and Rectal Microbiota Over Several Menstrual Cycles in Female Cynomolgus Macaques
Marie-Thérèse Nugeyre
,
Nicolas Tchitchek
,
Cindy Adapen
,
Claude Cannou
,
Vanessa Contreras
Article dans une revue
inserm-02433779v1
|
|
Progenitors from the central nervous system drive neurogenesis in cancer
Philippe Mauffrey
,
Nicolas Tchitchek
,
Vilma Barroca
,
Alexis-Pierre Bemelmans
,
Virginie Firlej
Article dans une revue
hal-03987060v1
|
|
Innate gene signature distinguishes humoral versus cytotoxic responses to influenza vaccination
Elena Gonçalves
,
Olivia Bonduelle
,
Angèle Soria
,
Pierre Loulergue
,
Alexandra Rousseau
Article dans une revue
hal-03160706v1
|
|
CytoBackBone: an algorithm for merging of phenotypic information from different cytometric profiles.
Adrien Leite Pereira
,
Olivier Lambotte
,
Roger Le Grand
,
Antonio Cosma
,
Nicolas Tchitchek
Article dans une revue
hal-03961015v1
|
|
Characterization of Leukocytes From HIV-ART Patients Using Combined Cytometric Profiles of 72 Cell Markers.
Adrien Leite Pereira
,
Nicolas Tchitchek
,
Olivier Lambotte
,
Roger Le Grand
,
Antonio Cosma
Article dans une revue
hal-03961014v1
|
|
Early blood transcriptomic signature predicts patients’ outcome after out-of-hospital cardiac arrest
Renaud Tissier
,
Hakim Hocini
,
Nicolas Tchitchek
,
Nicolas Deye
,
Stéphane Legriel
Article dans une revue
hal-03485659v1
|
|
NK cell immune responses differ after prime and boost vaccination
Jean‐louis Palgen
,
Nicolas Tchitchek
,
Nicolas Huot
,
Jamila Elhmouzi-Younes
,
Cécile Lefebvre
Article dans une revue
hal-02385954v1
|
|
Mass Cytometry Analysis Reveals Complex Cell-State Modifications of Blood Myeloid Cells During HIV Infection
Sixtine Coindre
,
Nicolas Tchitchek
,
Lamine Alaoui
,
Bruno Vaslin
,
Christine Bourgeois
Article dans une revue
hal-02386129v1
|
|
Seminal Plasma Exposures Strengthen Vaccine Responses in the Female Reproductive Tract Mucosae
Romain Marlin
,
Marie-Thérèse Nugeyre
,
Nicolas Tchitchek
,
Matteo Parenti
,
Cécile Lefebvre
Article dans une revue
inserm-02433796v1
|
|
Intradermal vaccination prevents anti-MOG autoimmune encephalomyelitis in macaques
Claire-Maëlle Fovet
,
Lev Stimmer
,
Vanessa Contreras
,
Philippe Horellou
,
Audrey Hubert
Article dans une revue
hal-02305565v1
|
|
Progenitors from the central nervous system drive neurogenesis in cancer
Philippe Mauffrey
,
Nicolas Tchitchek
,
Vilma Barroca
,
Alexis-Pierre Bemelmans
,
Virginie Firlej
Article dans une revue
cea-02186559v1
|
|
Characterization of Phenotypes and Functional Activities of Leukocytes From Rheumatoid Arthritis Patients by Mass Cytometry.
Adrien Leite Pereira
,
Samuel Bitoun
,
Audrey Paoletti
,
Gaetane Nocturne
,
Ernesto Marcos Lopez
Article dans une revue
hal-03961013v1
|
|
Cynomolgus macaque IL37 polymorphism and control of SIV infection
Takashi Shiina
,
Shingo Suzuki
,
Nicolas Congy-Jolivet
,
Alice Aarnink
,
Henri-Jean Garchon
Article dans une revue
hal-02149363v1
|
|
Molecular and cellular Dynamics in the skin, the lymph nodes, and the Blood of the immune response to intradermal injection of Modified Vaccinia ankara Vaccine
Pierre Rosenbaum
,
Nicolas Tchitchek
,
Candie Joly
,
Lev Stimmer
,
Hakim Hocini
Article dans une revue
hal-02386077v1
|
|
A high-resolution mass cytometry analysis reveals a delay of cytokines production after TLR4 or TLR7/8 engagements in HIV-1 infected humans
Adrien Leite Pereira
,
Nicolas Tchitchek
,
Ernesto Marcos Lopez
,
Olivier Lambotte
,
Roger Le Grand
Article dans une revue
hal-03854788v1
|
|
Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response
Jean-Louis Palgen
,
Nicolas Tchitchek
,
Jamila Elhmouzi-Younes
,
Simon Delandre
,
Inana Namet
Article dans une revue
hal-03984523v1
|
|
Prime and Boost Vaccination Elicit a Distinct Innate Myeloid Cell Immune Response
Jean-Louis Palgen
,
Nicolas Tchitchek
,
Jamila Elhmouzi-Younes
,
Simon Delandre
,
Inana Namet
Article dans une revue
hal-02385941v1
|
|
Mass Cytometry Analysis Reveals the Landscape and Dynamics of CD32a+ CD4+ T Cells From Early HIV Infection to Effective cART
Sixtine Coindre
,
Nicolas Tchitchek
,
Lamine Alaoui
,
Bruno Vaslin
,
Christine Bourgeois
Article dans une revue
hal-02386113v1
|
|
Stage-specific IFN-induced and IFN gene expression reveal convergence of type I and type II IFN and highlight their role in both acute and chronic stage of pathogenic SIV infection
Nadia Echebli
,
Nicolas Tchitchek
,
Stéphanie Dupuy
,
Timothée Bruel
,
Caroline Passaes
Article dans une revue
pasteur-02861901v1
|
|
Navigating in the vast and deep oceans of high-dimensional biological data.
Nicolas Tchitchek
Article dans une revue
hal-03961017v1
|
|
Molecular and Cellular Dynamics in the Skin, the Lymph Nodes, and the Blood of the Immune Response to Intradermal Injection of Modified Vaccinia Ankara Vaccine
Pierre Rosenbaum
,
Nicolas Tchitchek
,
Candie Joly
,
Lev Stimmer
,
Hakim Hocini
Article dans une revue
hal-03984590v1
|
|
Attenuated and vectored vaccines protect nonhuman primates against Chikungunya virus.
Pierre Roques
,
Karl Ljungberg
,
Beate M. Kümmerer
,
Leslie Gosse
,
Nathalie Dereuddre-Bosquet
Article dans une revue
hal-03961019v1
|
|
Listeriomics : an Interactive Web Platform for Systems Biology of Listeria
Christophe Bécavin
,
Mikael Koutero
,
Nicolas Tchitchek
,
Franck Cerutti
,
Pierre Lechat
Article dans une revue
pasteur-01574970v1
|
|
SPADEVizR: an R package for Visualization, Analysis and Integration of SPADE results
Guillaume Gautreau
,
David Pejoski
,
Roger Le Grand
,
Antonio Cosma
,
Anne-Sophie Beignon
Article dans une revue
hal-02385937v1
|
|
A computational approach for phenotypic comparisons of cell populations in high-dimensional cytometry data
Ludovic Platon
,
David Pejoski
,
Guillaume Gautreau
,
Brice Targat
,
Roger Le Grand
Article dans une revue
hal-02386051v1
|
|
In depth comparative phenotyping of blood innate myeloid leukocytes from healthy humans and macaques using mass cytometry.
Jamila Elhmouzi-Younes
,
Jean-Louis Palgen
,
Nicolas Tchitchek
,
Simon Delandre
,
Inana Namet
Cytometry. Part A : the journal of the International Society for Analytical Cytology, 2017, 91 (10), pp.969--982. ⟨10.1002/cyto.a.23107⟩
Article dans une revue
hal-03961018v1
|
|
Modified Vaccinia Virus Ankara Vector Induces Specific Cellular and Humoral Responses in the Female Reproductive Tract, the Main HIV Portal of Entry
Romain Marlin
,
Marie-Thérèse Nugeyre
,
Nicolas Tchitchek
,
Matteo Parenti
,
Hakim Hocini
Article dans une revue
pasteur-01597708v1
|
|
Analysis methodology and development of a statistical tool for biodistribution data from internal contamination with actinides
Stephanie Lamart
,
Nina Griffiths
,
Nicolas Tchitchek
,
Jaime Angulo
,
Anne van der Meeren
Article dans une revue
hal-03856452v1
|
|
The 1918 influenza virus PB2 protein enhances virulence through the disruption of inflammatory and Wnt-mediated signaling in mice
Adriana Forero
,
Jennifer Tisoncik-Go
,
Tokiko Watanabe
,
Gongxun Zhong
,
Masato Hatta
Article dans une revue
hal-03851553v1
|
|
Myocardial Gene Expression Profiling to Predict and Identify Cardiac Allograft Acute Cellular Rejection: The GET-Study
Diane Bodez
,
Hakim Hocini
,
Nicolas Tchitchek
,
Pascaline Tisserand
,
Nicole Benhaiem
Article dans une revue
hal-03987039v1
|
|
The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice
Adriana Forero
,
Jennifer Tisoncik-Go
,
Tokiko Watanabe
,
Gongxun Zhong
,
Masato Hatta
Article dans une revue
hal-04493274v1
|
|
Identification of Vaccine-Altered Circulating B Cell Phenotypes Using Mass Cytometry and a Two-Step Clustering Analysis.
David Pejoski
,
Nicolas Tchitchek
,
André Rodriguez Pozo
,
Jamila Elhmouzi-Younes
,
Rahima Yousfi-Bogniaho
Article dans une revue
hal-03961021v1
|
|
The 1918 Influenza Virus PB2 Protein Enhances Virulence through the Disruption of Inflammatory and Wnt-Mediated Signaling in Mice
Adriana Forero
,
Jennifer Tisoncik-Go
,
Tokiko Watanabe
,
Gongxun Zhong
,
Masato Hatta
Article dans une revue
hal-04493263v1
|
|
Evidence of IL-17, IP-10, and IL-10 involvement in multiple-organ dysfunction and IL-17 pathway in acute renal failure associated to Plasmodium falciparum malaria.
Fabien Herbert
,
Nicolas Tchitchek
,
Devendra Bansal
,
Julien Jacques
,
Sulabha Pathak
Article dans une revue
hal-02051283v1
|
|
Delayed Inflammatory and Cell Death Responses Are Associated with Reduced Pathogenicity in Lujo Virus-Infected Cynomolgus Macaques
Angela L Rasmussen
,
Nicolas Tchitchek
,
David Safronetz
,
Victoria S Carter
,
Christopher M Williams
Article dans une revue
hal-03851569v1
|
|
A comprehensive collection of systems biology data characterizing the host response to viral infection.
Brian D. Aevermann
,
Brett E. Pickett
,
Sanjeev Kumar
,
Edward B. Klem
,
Sudhakar Agnihothram
Article dans une revue
hal-03961036v1
|
|
H7N9 and other pathogenic avian influenza viruses elicit a three-pronged transcriptomic signature that is reminiscent of 1918 influenza virus and is associated with lethal outcome in mice.
Juliet Morrison
,
Laurence Josset
,
Nicolas Tchitchek
,
Jean Chang
,
Jessica A. Belser
Article dans une revue
hal-03961023v1
|
|
Annotation of long non-coding RNAs expressed in collaborative cross founder mice in response to respiratory virus infection reveals a new class of interferon-stimulated transcripts.
Laurence Josset
,
Nicolas Tchitchek
,
Lisa E. Gralinski
,
Martin T. Ferris
,
Amie J. Eisfeld
Article dans une revue
hal-03961024v1
|
|
Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome.
Nicolas Tchitchek
,
David Safronetz
,
Angela L. Rasmussen
,
Craig Martens
,
Kimmo Virtaneva
Article dans une revue
hal-03961022v1
|
|
1918 Influenza Virus Hemagglutinin (HA) and the Viral RNA Polymerase Complex Enhance Viral Pathogenicity, but Only HA Induces Aberrant Host Responses in Mice
Tokiko Watanabe
,
Jennifer Tisoncik-Go
,
Nicolas Tchitchek
,
Shinji Watanabe
,
Arndt G. Benecke
Article dans une revue
hal-01543311v1
|
|
Specific mutations in H5N1 mainly impact the magnitude and velocity of the host response in mice
Nicolas Tchitchek
,
Amie Eisfeld
,
Jennifer Tisoncik-Go
,
Laurence Josset
,
Lisa Gralinski
Article dans une revue
pasteur-00850969v1
|
|
A Network Integration Approach to Predict Conserved Regulators Related to Pathogenicity of Influenza and SARS-CoV Respiratory Viruses
Hugh D. Mitchell
,
Amie J. Eisfeld
,
Amy C. Sims
,
Jason E. Mcdermott
,
Melissa M. Matzke
Article dans une revue
hal-01543316v1
|
|
Systems approaches to influenza-virus host interactions and the pathogenesis of highly virulent and pandemic viruses.
Marcus J. Korth
,
Nicolas Tchitchek
,
Arndt G. Benecke
,
Michael G. Katze
Article dans une revue
hal-03961025v1
|
|
CDS: A Fold-change Based Statistical Test for Concomitant Identification of Distinctness and Similarity in Gene Expression Analysis
Nicolas Tchitchek
,
José Felipe Golib Dzib
,
Brice Targat
,
Sebastian Noth
,
Arndt Benecke
Article dans une revue
hal-01544156v1
|
|
2009 pandemic H1N1 influenza virus elicits similar clinical course but differential host transcriptional response in mouse, macaque, and swine infection models
Jennifer Go
,
Sarah Belisle
,
Nicolas Tchitchek
,
Terrence Tumpey
,
Wenjun Ma
Article dans une revue
hal-03849383v1
|
|
Expression sequence tag library derived from peripheral blood mononuclear cells of the chlorocebus sabaeus.
Nicolas Tchitchek
,
Béatrice Jacquelin
,
Patrick Wincker
,
Carole Dossat
,
Corinne Da Silva
Article dans une revue
inserm-00771549v1
|
|
A chemokine gene expression signature derived from meta-analysis predicts the pathogenicity of viral respiratory infections
Stewart Chang
,
Nicolas Tchitchek
,
Debashis Ghosh
,
Arndt Benecke
,
Michael Katze
Article dans une revue
hal-03849356v1
|
|
Improving the efficiency of multidimensional scaling in the analysis of high-dimensional data using singular value decomposition.
Christophe Bécavin
,
Nicolas Tchitchek
,
Colette Mintsa-Eya
,
Annick Lesne
,
Arndt Benecke
Article dans une revue
hal-03961026v1
|
|
Mineralocorticoid receptor mutations differentially affect individual gene expression profiles in pseudohypoaldosteronism type 1.
Fábio L. Fernandes-Rosa
,
Edwige-Ludiwyne Hubert
,
Jérome Fagart
,
Nicolas Tchitchek
,
Debora Gomes
Article dans une revue
hal-03961027v1
|
|
The microbiota mediates pathogen clearance from the gut lumen after non-typhoidal salmonella diarrhea.
Kathrin Endt
,
Bärbel Stecher
,
Samuel Chaffron
,
Emma Slack
,
Nicolas Tchitchek
Article dans une revue
inserm-00520162v1
|