Access content directly

Pascal Pigeon

81%
Open access
110
Documents
Current affiliations
  • 91000
Researcher identifiers
Web site
  • https://ipcm.fr/index.php/en/en-research/en-presentation-chembio-group/en-chembio-group-members/en-pascal-pigeon/

Presentation

Research domains

Organic chemistry Medicinal Chemistry

Publications

Image document

Deciphering the Diversified Metabolic Behavior of Hydroxyalkyl Ferrocidiphenols as Anticancer Complexes

Hui Wang , Xuejing Fan , Pei-Pei Xie , Shuang Yang , Pascal Pigeon
Journal of Medicinal Chemistry, 2024, 67 (2), pp.1209-1224. ⟨10.1021/acs.jmedchem.3c01709⟩
Journal articles hal-04369370v1
Image document

How Does Ferrocene Correlate with Ferroptosis? Multiple Approaches to Explore Ferrocene-Appended GPX4 Inhibitors as Anticancer Agents

Wei Li , Jing Yu , Jing Wang , Xuejing Fan , Ximing Xu
Chemical Science, inPress, ⟨10.1039/D4SC02002B⟩
Journal articles hal-04601570v1
Image document

Unravelling the Role of Uncommon Hydrogen Bonds in Cyclodextrin Ferrociphenol Supramolecular Complexes: A Computational Modelling and Experimental Study

Pascal Pigeon , Feten Najlaoui , Michael James Mcglinchey , Juan Sanz García , Gérard Jaouen
International Journal of Molecular Sciences, 2023, Special Issue Cyclodextrins: Properties and Applications, 24 (15), pp.12288. ⟨10.3390/ijms241512288⟩
Journal articles hal-04176438v1
Image document

Physicochemical Characterization of Ferrocifen Lipid Nanocapsules: Customized Drug Delivery Systems Guided by the Molecular Structure

Pierre Idlas , Elise Lepeltier , Guillaume Bastiat , Pascal Pigeon , Michael Mcglinchey
Langmuir, 2023, 39 (5), pp.1885-1896. ⟨10.1021/acs.langmuir.2c02910⟩
Journal articles hal-03955374v1
Image document

α-Hydroxylactams as Efficient Entries to Diversely Functionalized Ferrociphenols: Synthesis and Antiproliferative Activity Studies

Pascal Pigeon , Marie Gaschard , Mohamed Othman , Michèle Salmain , Gérard Jaouen
Molecules, 2022, 27 (14), pp.4549. ⟨10.3390/molecules27144549⟩
Journal articles hal-03736842v1
Image document

Synthesis, Electrochemical and Fluorescence Properties of the First Fluorescent Member of the Ferrocifen Family and of its Oxidized Derivatives

Charles Fayolle , Pascal Pigeon , Nathalie Fischer-Durand , Michèle Salmain , Olivier O. Buriez
Molecules, 2022, 27 (19), pp.6690. ⟨10.3390/molecules27196690⟩
Journal articles hal-03807919v1
Image document

Ferrocifen stealth LNCs and conventional chemotherapy: A promising combination against multidrug-resistant ovarian adenocarcinoma

Pierre Idlas , Abdallah Ladaycia , Fariba Némati , Elise Lepeltier , Pascal Pigeon
International Journal of Pharmaceutics, 2022, 626, pp.122164. ⟨10.1016/j.ijpharm.2022.122164⟩
Journal articles hal-03774820v1
Image document

Succinimido–Ferrocidiphenol Complexed with Cyclodextrins Inhibits Glioblastoma Tumor Growth In Vitro and In Vivo without Noticeable Adverse Toxicity

Feten Najlaoui , Benoît Busser , Germain Sotoing Taïwe , Pascal Pigeon , Nathalie Sturm
Molecules, 2022, 27 (14), pp.4651. ⟨10.3390/molecules27144651⟩
Journal articles hal-03736856v1
Image document

Diversity-oriented synthesis and bioactivity evaluation of N-substituted ferrocifen compounds as novel antiproliferative agents against TNBC cancer cells

Yong Wang , Pascal Pigeon , Wei Li , Jiangkun Yan , Patrick M Dansette
European Journal of Medicinal Chemistry, 2022, 234, pp.114202. ⟨10.1016/j.ejmech.2022.114202⟩
Journal articles hal-03599161v1
Image document

Inhibition of cathepsin B by ferrocenyl indenes highlights a new pharmacological facet of ferrocifens

Juan Sanz Garcia , Marie Gaschard , Isabelle Navizet , Mehdi Sahihi , Siden Top
European Journal of Inorganic Chemistry, 2022, 2022 (9), pp.e202101075. ⟨10.1002/ejic.202101075⟩
Journal articles hal-03527077v1
Image document

Heterogeneity of Response to Iron-Based Metallodrugs in Glioblastoma Is Associated with Differences in Chemical Structures and Driven by FAS Expression Dynamics and Transcriptomic Subtypes

Anne Vessieres , Emie Quissac , Nolwenn Lemaire , Agusti Alentorn , Patrycja Domeracka
International Journal of Molecular Sciences, 2021, 22 (19), pp.10404. ⟨10.3390/ijms221910404⟩
Journal articles hal-03356305v1
Image document

Antimicrobial, antitumor and side effects assessment of a newly synthesized tamoxifen analogue

Fatma Abdmouleh , Mehdi El Arbi , Hajer Ben Saad , Karim Jellali , Emna E. Ketata
Current Topics in Medicinal Chemistry, 2020, 20 (25), pp.2281-2288. ⟨10.2174/1568026620666200819145526⟩
Journal articles hal-02921197v1
Image document

Atypical lone pair-π interaction with quinone methides in a series of imido-ferrociphenol anticancer drug candidates

Yong Wang , Pascal Pigeon , Siden Top , Juan Garcia , Claire Troufflard
Angewandte Chemie International Edition, 2019, 58 (25), pp.8421-8425. ⟨10.1002/anie.201902456⟩
Journal articles hal-02103918v1
Image document

Small Structural Differences between Two Ferrocenyl Diphenols Determine Large Discrepancies of Reactivity and Biological Effects

Federica Tonolo , Michèle Salmain , Valeria Scalcon , Siden Top , Pascal Pigeon
ChemMedChem, 2019, 14 (19), pp.1717-1726. ⟨10.1002/cmdc.201900430⟩
Journal articles hal-02282225v1
Image document

Importance of Combining Advanced Particle Size Analysis Techniques To Characterize Cell-Penetrating Peptide–Ferrocifen Self-Assemblies

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi
Journal of Physical Chemistry Letters, 2019, 10 (21), pp.6613-6620. ⟨10.1021/acs.jpclett.9b01493⟩
Journal articles hal-02319158v1
Image document

A new generation of ferrociphenols leads to a great diversity of reactive metabolites, and exhibits remarkable antiproliferative properties

Yong Wang , Patrick M Dansette , Pascal Pigeon , Siden Top , Michael James Mcglinchey
Chemical Science, 2018, 9, pp.70-78. ⟨10.1039/C7SC04213B⟩
Journal articles hal-01646922v1
Image document

Selective cytotoxicity of arene tricarbonylchromium towards tumour cell lines

Jihene Elloumi-Mseddi , Sami Mnif , Nejmeddine Akacha , Bochra Hakim , Pascal Pigeon
Journal of Organometallic Chemistry, 2018, 862, pp.7-12. ⟨10.1016/j.jorganchem.2018.01.036⟩
Journal articles hal-01720644v1
Image document

Enhanced and preferential internalization of lipid nanocapsules into human glioblastoma cells: effect of a surface-functionalizing NFL peptide

Reatul Karim , Elise Lepeltier , Lucille Esnault , Pascal Pigeon , Laurent Lemaire
Nanoscale, 2018, 10, pp.13485-13501. ⟨10.1039/C8NR02132E⟩
Journal articles hal-01817763v1
Image document

Aryl butenes active against K562 cells and lacking tyrosinase inhibitory activity as new leads in the treatment of leukemia

Mehdi El Arbi , Emna E. Ketata , Aref Neifar , Wafa Mihoubi , Girish K. G. K. Gupta
Mini-Reviews in Medicinal Chemistry, 2018, 18 (15), pp.1294-1301. ⟨10.2174/1389557517666170208142254⟩
Journal articles hal-01479613v1
Image document

Anticancer properties of lipid and poly(ε-caprolactone) nanocapsules loaded with ferrocenyl-tamoxifen derivatives

Feten Najlaoui , Pascal Pigeon , Sonia Aroui , Mylène Pezet , Lucie Sancey
Journal of Pharmacy and Pharmacology, 2018, 70 (11), pp.1474-1484. ⟨10.1111/jphp.12998⟩
Journal articles hal-01861749v1

The inhibition of tyrosinase by some aryl butenes: A desired activity or a side effect to avoid

Emna E. Ketata , Aref Neifar , Wafa Mihoubi , Pascal Pigeon , Hicham Gouzi
Journal of Organometallic Chemistry, 2017, 848, pp.133 - 141. ⟨10.1016/j.jorganchem.2017.07.031⟩
Journal articles hal-01611372v1
Image document

A New Series of Succinimido-ferrociphenols and Related Heterocyclic Species Induce Strong Antiproliferative Effects, Especially against Ovarian Cancer Cells Resistant to Cisplatin

Pascal Pigeon , Yong Wang , Siden Top , Feten Najlaoui , Maria Concepcion Garcia Alvarez
Journal of Medicinal Chemistry, 2017, 60 (20), pp.8358-8368. ⟨10.1021/acs.jmedchem.7b00743⟩
Journal articles hal-01611795v1
Image document

Tamoxifen-like metallocifens target the thioredoxin system determining mitochondrial impairment leading to apoptosis in Jurkat cells

Valeria Scalcon , Michèle Salmain , Alessandra Folda , Siden Top , Pascal Pigeon
Metallomics, 2017, 9 (7), pp.949-959. ⟨10.1039/C7MT00121E⟩
Journal articles hal-01611386v1
Image document

Side-Chain Effects on the 1-(Bis-aryl-methylidene)-[3]ferrocenophane Skeleton: Antiproliferative Activity against TNBC Cancer Cells and Comparison with the Acyclic Ferrocifen Series

Meral Gormen , Pascal Pigeon , Yong Wang , Anne Vessières , Siden Top
European Journal of Inorganic Chemistry, 2017, Special Issue: The Multifaceted Chemistry of Ferrocene (Cluster Issue), 2017 (2), pp.454-465. ⟨10.1002/ejic.201601088⟩
Journal articles hal-01408995v1
Image document

Synthesis and antiproliferative evaluation of novel hydroxypropyl-ferrociphenol derivatives, resulting from the modification of hydroxyl groups

Wang Yong , Pascal Pigeon , Michael J. Mcglinchey , Siden Top , Gérard Jaouen
Journal of Organometallic Chemistry, 2017, 829, pp.108-115. ⟨10.1016/j.jorganchem.2016.09.005⟩
Journal articles hal-01484511v1
Image document

Efficacy of a novel ferrocenyl diaryl butene citrate compound as a biocide for preventing healthcare-associated infections

Mehdi El Arbi , Karim Jalléli , Fatma Trigui , Pascal Pigeon , Meral Görmen
MedChemComm, 2016, 7 (5), pp.948-954. ⟨10.1039/C5MD00568J⟩
Journal articles hal-01289145v1
Image document

Enzymatic oxidation of ansa-ferrocifen leads to strong and selective thioredoxin reductase inhibition in vitro

Valeria Scalcon , Anna Citta , Alessandra Folda , Alberto Bindoli , Michèle Salmain
Journal of Inorganic Biochemistry, 2016, 165, pp.146-151. ⟨10.1016/j.jinorgbio.2016.08.005⟩
Journal articles hal-01401089v1
Image document

Ferrocenyl Quinone Methide-Thiol Adducts as New Antiproliferative Agents: Synthesis, Metabolic Formation from Ferrociphenols, and Oxidative Transformation

Yong Wang , Marie-Aude Richard , Siden Top , Patrick M. Dansette , Pascal Pigeon
Angewandte Chemie, 2016, 55 (35), pp.10431-10434. ⟨10.1002/anie.201603931⟩
Journal articles hal-01345781v1
Image document

The length of the bridging chain in ansa-metallocenes influences their antiproliferative activity against triple negative breast cancer cells (TNBC)

Matthieu Beauperin , Siden Top , Marie-Aude Richard , Damian Plażuk , Pascal Pigeon
Dalton Transactions, 2016, 45, pp.13126-13134. ⟨10.1039/C6DT01640E⟩
Journal articles hal-01338321v1
Image document

Antiplasmodial activity of iron(II) and ruthenium(II) organometallic complexes against Plasmodium falciparum blood parasites

Nicolli Bellotti De Souza , Anna Caroline Campos Aguiar , Alane Cabral De Oliveira , Siden Top , Pascal Pigeon
Memórias do Instituto Oswaldo Cruz, 2015, 110 (8), pp.981-988. ⟨10.1590/0074-02760150163⟩
Journal articles hal-01261304v1
Image document

Phthalimido-ferrocidiphenol cyclodextrin complexes: Characterization and anticancer activity

Feten Najlaoui , Pascal Pigeon , Zaineb Abdelkafi , Sebastien Leclerc , Pierrick Durand
International Journal of Pharmaceutics, 2015, 491 (1-2), pp.323-334. ⟨10.1016/j.ijpharm.2015.06.043⟩
Journal articles hal-01218567v1
Image document

Oxidative Metabolism of Ferrocene Analogues of Tamoxifen: Characterization and Antiproliferative Activities of the Metabolites

Marie-Aude Richard , Didier Hamels , Pascal Pigeon , Siden Top , Patrick M. Dansette
ChemMedChem, 2015, 10 (6), pp.981-990. ⟨10.1002/cmdc.201500075⟩
Journal articles hal-01230370v1
Image document

Organometallic Antitumor Compounds: Ferrocifens as Precursors to Quinone Methides

Yong Wang , Pascal Pigeon , Siden Top , Michael J. Mcglinchey , Gérard Jaouen
Angewandte Chemie International Edition, 2015, 54 (35), pp.10230-10233. ⟨10.1002/anie.201503048⟩
Journal articles hal-01230371v1
Image document

Atypical McMurry Cross-Coupling Reactions Leading to a New Series of Potent Antiproliferative Compounds Bearing the Key [Ferrocenyl-Ene-Phenol] Motif

Pascal Pigeon , Meral Goermen , Konrad Kowalski , Helge Mueller-Bunz , Michael J. Mcglinchey
Molecules, 2014, 19 (7), pp.10350-10369. ⟨10.3390/molecules190710350⟩
Journal articles hal-01230372v1
Image document

Molecular Mechanism of Action of 2-Ferrocenyl-1,1-diphenylbut-1-ene on HL-60 Leukemia Cells

Alane Cabral De Oliveira , Emanuella Gomes Da Silva , Danilo Damasceno Rocha , Elisabeth A. Hillard , Pascal Pigeon
ChemMedChem, 2014, 9 (11), pp.2580-2586. ⟨10.1002/cmdc.201402219⟩
Journal articles hal-01230375v1
Image document

Ferrocifen derivatives that induce senescence in cancer cells: selected examples

Celine Bruyere , Veronique Mathieu , Anne Vessières , Pascal Pigeon , Siden Top
Journal of Inorganic Biochemistry, 2014, 141, pp.144-151. ⟨10.1016/j.jinorgbio.2014.08.015⟩
Journal articles hal-01230377v1

Antibacterial properties and mode of action of new triaryl butene citrate compounds

Mehdi El Arbi , Jeremie Theolier , Pascal Pigeon , Karim Jellali , Fatma Trigui
European Journal of Medicinal Chemistry, 2014, 76, pp.408-413. ⟨10.1016/j.ejmech.2014.02.037⟩
Journal articles hal-01230373v1
Image document

Oxidative Sequence of a Ruthenocene-Based Anticancer Drug Candidate in a Basic Environment

Hui Zhi Shirley Lee , Olivier Buriez , Eric Labbé , Siden Top , Pascal Pigeon
Organometallics, 2014, 33 (18), pp.4940-4946. ⟨10.1021/om500225k⟩
Journal articles hal-01230374v1
Image document

Evidence for Targeting Thioredoxin Reductases with Ferrocenyl Quinone Methides. A Possible Molecular Basis for the Antiproliferative Effect of Hydroxyferrocifens on Cancer Cells

Anna Citta , Alessandra Folda , Alberto Bindoli , Pascal Pigeon , Siden Top
Journal of Medicinal Chemistry, 2014, 57 (21), pp.8849-8859. ⟨10.1021/jm5013165⟩
Journal articles hal-01230376v1
Image document

The in vivo performance of ferrocenyl tamoxifen lipid nanocapsules in xenografted triple negative breast cancer

Anne-Laure Lainé , Eric Adriaenssens , Anne Vessières , Gérard Jaouen , Cyril Corbet
Biomaterials, 2013, 34 (28), pp.6949-6956. ⟨10.1016/j.biomaterials.2013.05.065⟩
Journal articles hal-01230382v1
Image document

Selection of a suitable disc bioassay for the screening of anti-tumor molecules

Fatma Trigui , Pascal Pigeon , Karim Jalleli , Siden Top , Sami Aifa
International journal of biomedical science: IJBS, 2013, 9 (4), pp.230--236
Journal articles hal-01230383v1
Image document

Ferrocenyl flavonoid-induced morphological modifications of endothelial cells and cytotoxicity against B16 murine melanoma cells

Jean-Philippe Monserrat , Keshri Nath Tiwari , Lionel Quentin , Pascal Pigeon , Gérard Jaouen
Journal of Organometallic Chemistry, 2013, 734 (SI), pp.78-85. ⟨10.1016/j.jorganchem.2012.12.031⟩
Journal articles hal-01230380v1
Image document

Effect of the amino chain length and the transformation into citric acid salts of aryl-diphenyl-butenes and ferrocenyl-diphenyl-butenes bearing two dimethylaminoalkyl chains on their antimicrobial activities

Karim Jellali , Pascal Pigeon , Fatma Trigui , Siden Top , Sami Aifa
SpringerPlus, 2013, 2 (1), pp.508. ⟨10.1186/2193-1801-2-508⟩
Journal articles hal-01230378v1
Image document

Ferrocenyl catechols: synthesis, oxidation chemistry and anti-proliferative effects on MDA-MB-231 breast cancer cells

Yong Leng Kelvin Tan , Pascal Pigeon , Siden Top , Eric Labbé , Olivier Buriez
Dalton Transactions, 2012, 41 (25), pp.7537-7549. ⟨10.1039/c2dt30700f⟩
Journal articles hal-01230385v1
Image document

Synthesis and Antiproliferative Effects of [3]Ferrocenophane Transposition Products and Pinacols Obtained from McMurry Cross-Coupling Reactions

Meral Görmen , Pascal Pigeon , Elisabeth A. Hillard , Anne Vessières , Michel Huché
Organometallics, 2012, 31 (16), pp.5856-5866. ⟨10.1021/om300382h⟩
Journal articles hal-01230386v1
Image document

Biological evaluation of twenty-eight ferrocenyl tetrasubstituted olefins: Cancer cell growth inhibition, ROS production and hemolytic activity

Alane Cabral De Oliveira , Elisabeth A. Hillard , Pascal Pigeon , Danilo Damasceno Rocha , Felipe A. R. Rodrigues
European Journal of Medicinal Chemistry, 2011, 46 (9), pp.3778-3787. ⟨10.1016/j.ejmech.2011.05.043⟩
Journal articles hal-01230389v1
Image document

A new series of ferrocifen derivatives, bearing two aminoalkyl chains, with strong antiproliferative effects on breast cancer cells

Pascal Pigeon , Siden Top , Anne Vessières , Michel Huché , Meral Goermen
New Journal of Chemistry, 2011, 35 (10), pp.2212-2218. ⟨10.1039/c1nj20192a⟩
Journal articles hal-01230387v1

ANTIMICROBIAL EFFECT OF FERROCENYL DIARYL BUTENES AGAINST OLIVE PLANTLET DISEASES

M. El Arbi , Pascal Pigeon , A. Chaari Rkhis , Siden Top , A. Rhouma
Journal of Plant Pathology, 2011, 93 (3), pp.651-657
Journal articles hal-01230390v1

Evaluation of bactericidal and fungicidal activity of ferrocenyl or phenyl derivatives in the diphenyl butene series

Mehdi El Arbi , Pascal Pigeon , Siden Top , Ali Rhouma , Sami Aifa
Journal of Organometallic Chemistry, 2011, 696 (5), pp.1038-1048. ⟨10.1016/j.jorganchem.2010.09.015⟩
Journal articles hal-01230388v1
Image document

Facile synthesis and strong antiproliferative activity of disubstituted diphenylmethylidenyl-[3]ferrocenophanes on breast and prostate cancer cell lines

Meral Görmen , Pascal Pigeon , Siden Top , Anne Vessières , Marie-Aude Plamont
MedChemComm, 2010, 1 (2), pp.149-151. ⟨10.1039/c0md00026d⟩
Journal articles hal-01230393v1

Antiparasitic and Immunomodulatory Activities of 1,1-bis(4-Hydroxyphenyl)-2-Phenyl-but-1-ene and Its Protected and Free 2-Ferrocenyl Derivatives

Milena B. P. Soares , Jose Fernando Oliveira Costa , Matheus Santos De Sa , Ricardo Ribeiro-Dos-Santos , Pascal Pigeon
Drug Development Research, 2010, 71 (1, SI), pp.69-75. ⟨10.1002/ddr.20349⟩
Journal articles hal-01230392v1
Image document

Comparative toxicity of [3]ferrocenophane and ferrocene moieties on breast cancer cells

Meral Görmen , Damian Plazuk , Pascal Pigeon , Elisabeth A. Hillard , Marie-Aude Plamont
Tetrahedron Letters, 2010, 51 (1), pp.118-120. ⟨10.1016/j.tetlet.2009.10.102⟩
Journal articles hal-01230391v1
Image document

Synthesis, Cytotoxicity, and COMPARE Analysis of Ferrocene and [3]Ferrocenophane Tetrasubstituted Olefin Derivatives against Human Cancer Cells

Meral Goermen , Pascal Pigeon , Siden Top , Elisabeth A. Hillard , Michel Huché
ChemMedChem, 2010, 5 (12), pp.2039-2050. ⟨10.1002/cmdc.201000286⟩
Journal articles hal-01230394v1
Image document

Synthesis and Structure-Activity Relationships of Ferrocenyl Tamoxifen Derivatives with Modified Side Chains.

A. Nguyen , S. Top , Pascal Pigeon , A. Vessieres , E.A. Hillard
Chemistry - A European Journal, 2009, 15, pp.684-696. ⟨10.1002/chem.200801108⟩
Journal articles hal-00376089v1
Image document

Role of aromatic substituents on the antiproliferative effects of diphenyl ferrocenyl butene compounds

Ouardia Zekri , Elisabeth A. Hillard , Siden Top , Anne Vessières , Pascal Pigeon
Dalton Transactions, 2009, 22, pp.4318-4326. ⟨10.1039/B819812H⟩
Journal articles hal-00449003v1
Image document

The replacement of a phenol group by an aniline or acetanilide group enhances the cytotoxicity of 2-ferrocenyl-1,1-diphenyl-but-1-ene compounds against breast cancer cells

Pascal Pigeon , Siden Top , Ouardia O. Zekri , Elisabeth A. Hillard , Anne A. Vessieres
Journal of Organometallic Chemistry, 2009, 694, pp.895-901. ⟨10.1016/j.jorganchem.2008.11.035⟩
Journal articles hal-00376093v1

Synthesis, oxidation chemistry and cytotoxicity studies on ferrocene derivatives of diethylstilbestrol

Yong Leng Kelvin Tan , Pascal Pigeon , Elisabeth A. Hillard , Siden Top , Marie-Aude Plamont
Dalton Transactions, 2009, 48, pp.10871-10881. ⟨10.1039/b913570g⟩
Journal articles hal-01230395v1
Image document

Dose effect activity of ferrocifen-loaded lipid nanocapsules on a 9L-glioma model

E. Allard , N. T. Huynh , A. Vessières , Pascal Pigeon , G. Jaouen
International Journal of Pharmaceutics, 2009, 379 (2), pp.317-323. ⟨10.1016/j.ijpharm.2009.05.031⟩
Journal articles hal-01230396v1
Image document

A [3]Ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines

Damian Plazuk , Anne Vessières , Elisabeth A. Hillard , Olivier Buriez , Eric Labbé
Journal of Medicinal Chemistry, 2009, 52, pp.4964-4967. ⟨10.1021/jm900297x⟩
Journal articles hal-00448988v1
Image document

Electrochemical attachment of a conjugated amino-ferrocifen complex onto carbon and metal surfaces

Olivier Buriez , Eric Labbé , Pascal Pigeon , Gérard Jaouen , Christian Amatore
Journal of electroanalytical chemistry and interfacial electrochemistry, 2008, 619, pp.169-175. ⟨10.1016/j.jelechem.2008.04.012⟩
Journal articles hal-01230398v1
Image document

Lipid nanocapsules loaded with an organometallic tamoxifen derivative as a novel drug-carrier system for experimental malignant gliomas.

Emilie Allard , Catherine Passirani , Emmanuel Garcion , Pascal Pigeon , Anne Vessières
Journal of Controlled Release, 2008, 130 (2), pp.146-53. ⟨10.1016/j.jconrel.2008.05.027⟩
Journal articles inserm-00343557v1
Image document

Nanoparticles loaded with ferrocenyl tamoxifen derivatives for breast cancer treatment.

Anh Nguyen , Véronique Marsaud , Céline Bouclier , Siden Top , Anne Vessieres
International Journal of Pharmaceutics, 2008, 347 (1-2), pp.128-35. ⟨10.1016/j.ijpharm.2007.06.033⟩
Journal articles hal-00180710v1
Image document

Ferrocenyl compounds possessing protected phenol and thiophenol groups: Synthesis, X-ray structure, and in vitro biological effects against breast cancer

Julia B. Heilmann , Elisabeth A. Hillard , Marie-Aude Plamont , Pascal Pigeon , Michael Bolte
Journal of Organometallic Chemistry, 2008, 693 (8-9), pp.1716-1722. ⟨10.1016/j.jorganchem.2007.12.011⟩
Journal articles hal-01230397v1
Image document

The influence of phenolic hydroxy substitution on the electron transfer and anti-cancer properties of compounds based on the 2-ferrocenyl-1-phenyl-but-1-ene motif

Elisabeth A. Hillard , Pascal Pigeon , Anne Vessières , Christian Amatore , Gérard Jaouen
Dalton Transactions, 2007, 43, pp.5073-5081. ⟨10.1039/b705030e⟩
Journal articles hal-01230399v1
Image document

Organometallic diphenols: The importance of the organometallic moiety on the expression of a cytotoxic effect on breast cancer cells

Elisabeth A. Hillard , Anne Vessières , Siden Top , Pascal Pigeon , Konrad Kowalski
Journal of Organometallic Chemistry, 2007, 692 (6), pp.1315-1326. ⟨10.1016/j.jorganchem.2006.10.041⟩
Journal articles hal-01230402v1
Image document

Ferrocifens and ferrocifenols as new potential weapons against breast cancer

Anh Nguyen , Anne Vessières , Elisabeth A. Hillard , Siden Top , Pascal Pigeon
CHIMIA, 2007, 61 (11), pp.716-724. ⟨10.2533/chimia.2007.716⟩
Journal articles hal-01230400v1
Image document

Organometallic analogues of tamoxifen: Effect of the amino side-chain replacement by a carbonyl ferrocenyl moiety in hydroxytamoxifen

Anh Nguyen , Siden Top , Anne Vessières , Pascal Pigeon , Michel Huché
Journal of Organometallic Chemistry, 2007, 692 (6, SI), pp.1219-1225. ⟨10.1016/j.jorganchem.2006.11.016⟩
Journal articles hal-01230401v1
Image document

Modification of the estrogenic properties of diphenols by the incorporation of ferrocene. Generation of antiproliferative effects in vitro

A Vessieres , Siden Top , Pascal Pigeon , E Hillard , L Boubeker
Journal of Medicinal Chemistry, 2005, 48 (12), pp.3937-3940. ⟨10.1021/jm050251o⟩
Journal articles hal-01230403v1
Image document

Selective estrogen receptor modulators in the ruthenocene series. Synthesis and biological behavior

Pascal Pigeon , Siden Top , Anne Vessières , Michel Huché , Elisabeth A. Hillard
Journal of Medicinal Chemistry, 2005, 48 (8), pp.2814-2821. ⟨10.1021/jm049268h⟩
Journal articles hal-00093015v1
Image document

Selective estrogen-receptor modulators (SERMs) in the cyclopentadienylrhenium tricarbonyl series: Synthesis and biological behaviour

Siden Top , A Vessieres , Pascal Pigeon , Mn Rager , M Huche
ChemBioChem, 2004, 5 (8), pp.1104-1113. ⟨10.1002/cbic.200400067⟩
Journal articles hal-01230404v1
Image document

A short route to cyclopentadienyl tricarbonylrhenium substituted derivatives

F Le Bideau , J Henique , Pascal Pigeon , Jm Joerger , Siden Top
Journal of Organometallic Chemistry, 2003, 668 (1-2), pp.140-144. ⟨10.1016/S0022-328X(02)02090-9⟩
Journal articles hal-01230405v1
Image document

Intramolecular addition of a hydroxyl to a N-acyliminium system. Application to the synthesis of isoindolo[2,1-a][3,1]benzoxazine and isoindolo[1,2-c][2,4] benzoxazepine derivatives

Pascal Pigeon , Jana Sikoraiova , S Marchalin , Bernard Decroix
Heterocycles, 2002, 56 (1-2), pp.129-138. ⟨10.3987/COM-01-S(K)5⟩
Journal articles hal-01230406v1
Image document

Thieno[2′,3′:5,6]azepino[2,1- a ]isoindolones from hydroxylactam-alcohols via N -acyliminium ion olefin cyclization

Pascal Pigeon , Mohamed Othman , Bernard Decroix
Journal of Heterocyclic Chemistry, 2001, 38 (1), pp.35 - 39. ⟨10.1002/jhet.5570380105⟩
Journal articles hal-01230407v1
Image document

Study of a 1,6-hydride shift in an open chain of hydroxylactam-triarylcarbinols

Pascal Pigeon , Aïcha Mamouni , Jana Sikoraiova , Stefan Marchalin , Bernard Decroix
Tetrahedron, 2001, 57 (23), pp.4939-4943. ⟨10.1016/S0040-4020(01)00437-9⟩
Journal articles hal-01230408v1
Image document

First anti-oestrogen in the cyclopentadienyl rhenium tricarbonyl series. Synthesis and study of antiproliferative effects

Gérard Jaouen , Siden Top , Anne Vessieres , Pascal Pigeon , Guy Leclercq
Chemical Communications, 2001, 4, pp.383-384. ⟨10.1039/b009553m⟩
Journal articles hal-01230409v1
Image document

Quinoxalines, benzodiazepines and benzodiazocines fused to pyrrole and isoindole via N-acyliminium ion aromatic cyclization

Mohamed Othman , Pascal Pigeon , Pierre Netchitaïlo , Abdel Daich , Bernard Decroix
Heterocycles, 2000, 52 (1), pp.273-281. ⟨10.3987/COM-99-S21⟩
Journal articles hal-01230410v1
Image document

Polycyclic systems: Synthesis of isoindolo[2,1-b]pyrrolo[1,2-d] [2,4]benzodiazocine and isoindolo[1,2-d]pyrrolo[1,2-a][1,5]benzodiazocine

Mohamed Othman , Pascal Pigeon , Bernard Decroix
Journal of Heterocyclic Chemistry, 1999, 36 (3), pp.735-738. ⟨10.1002/jhet.5570360326⟩
Journal articles hal-01230411v1
Image document

Acyliminium ion-olefin cyclization leading to isoindolo [2,1-a]quinoline derivatives

Pascal Pigeon , Mohamed Othman , Pierre Netchitaïlo , Bernard Decroix
Journal of Heterocyclic Chemistry, 1999, 36 (3), pp.691-695. ⟨10.1002/jhet.5570360319⟩
Journal articles hal-01230412v1

Synthesis and reduction of thieno[2 `,3 `(3 `,2 ` or 3 `,4 `): 5,6]-azocino[2,1-a]isoindole-7,13-diones

Mohamed Othman , Pascal Pigeon , Bernard Decroix
Journal of Heterocyclic Chemistry, 1998, 35 (6), pp.1429-1433. ⟨10.1002/jhet.5570350635⟩
Journal articles hal-01230418v1
Image document

New fused lactones from indolizinediones via N-acyliminium ions

Mohamed Othman , Pascal Pigeon , Bernard Decroix
Tetrahedron, 1998, 54 (30), pp.8737-8744. ⟨10.1016/S0040-4020(98)00468-2⟩
Journal articles hal-01230415v1
Image document

Synthesis of benzo(or furo)[5,6]azepino[2,1-a]isoindolone derivatives: pi-cyclisations of N-acyliminium ions.

Adam Daich , Stefan Marchalin , Pascal Pigeon , Bernard Decroix
Tetrahedron Letters, 1998, 39 (50), pp.9187-9190. ⟨10.1016/S0040-4039(98)02075-9⟩
Journal articles hal-01230414v1
Image document

Diisoindolothieno[2,4]diazepines via a diastereoselective N-acyliminium ion cyclization

Pascal Pigeon , Bernard Decroix
Tetrahedron Letters, 1998, 39 (47), pp.8659-8662. ⟨10.1016/S0040-4039(98)01979-0⟩
Journal articles hal-01230417v1
Image document

Novel approach to isoindolo[2,1-a]quinolines

Pascal Pigeon , Bernard Decroix
Synthetic Communications, 1998, 28 (13), pp.2507-2516. ⟨10.1080/00397919808004302⟩
Journal articles hal-01230413v1
Image document

Selective access to N-aryl or N-alkyl derivatives of isoindolo[2,1-b][2,4]benzo(or thieno)diazepines

Pascal Pigeon , Mohamed Othman , Pierre Netchitaïlo , Bernard Decroix
Tetrahedron, 1998, 54 (8), pp.1497-1506. ⟨10.1016/S0040-4020(97)10359-3⟩
Journal articles hal-01230416v1
Image document

Introduction of a carboxymethylamino (or oxy or thio) group in the 3 position of 2-aryl (or arylmethyl) isoindol-1-ones from alpha hydroxylactams

Pascal Pigeon , Bernard Decroix
Synthetic Communications, 1997, 27 (8), pp.1423-1431. ⟨10.1080/00397919708006073⟩
Journal articles hal-01230420v1
Image document

Intramolecular amidoalkylation cyclizations in synthesis of novel pyrrolo(or isoindolo)thieno[2]benzazepines

Aïcha Mamouni , Pascal Pigeon , Abdel Adam Daïch , Bernard Decroix
Journal of Heterocyclic Chemistry, 1997, 34 (5), pp.1495-1499. ⟨10.1002/jhet.5570340519⟩
Journal articles hal-01230424v1
Image document

A new access to isoindolo[2,1-b][2,4]benzodiazepines through an N-acyliminium ion amide cyclization

Pascal Pigeon , Bernard Decroix
Tetrahedron Letters, 1997, 38 (17), pp.2985-2988. ⟨10.1016/S0040-4039(97)00539-X⟩
Journal articles hal-01230422v1
Image document

Synthèses de thiéno[2’,3’(ou 3’,2’):5,6]azépino[2,1-a]isoindol-6-ones diversement substituées

Pascal Pigeon , Bernard Decroix
Bulletin de la Societe Chimique de France, 1997, 134 (2), pp.153-157
Journal articles hal-01230419v1
Image document

Acyliminium ion cyclizations: Synthesis of thieno[2',3':3,4]pyrrolo[2,1-a]isoindolone and benzo[a]thieno[2,3(3,2 or 3,4)-g]indolizinones

Mohamed Othman , Pascal Pigeon , Bernard Decroix
Tetrahedron, 1997, 53 (7), pp.2495-2504. ⟨10.1016/S0040-4020(96)01196-9⟩
Journal articles hal-01230423v1
Image document

Synthesis of dibenz[c,e]azepine and benzo[e]thieno[c]azepine via N-acyliminium ion cyclization

Pascal Pigeon , Bernard Decroix
Tetrahedron Letters, 1997, 38 (6), pp.1041-1042. ⟨10.1016/S0040-4039(96)02497-5⟩
Journal articles hal-01230421v1
Image document

Tetracyclic systems: Synthesis of isoindolo[1,2-b]thieno[2,3(3,2 or 3,4)-e][1,3]thiazocines and isoindolo[2,1-a]thieno[2,3(3,2 or 3,4)-f][1,4] and [1,5]diazocines

Pascal Pigeon , Bernard Decroix
Journal of Heterocyclic Chemistry, 1997, 34 (2), pp.375-380. ⟨10.1002/jhet.5570340203⟩
Journal articles hal-01230425v1
Image document

Benzothienoindolizidines via intramolecular aryl radical cyclization or palladium catalyzed cyclization

Pascal Pigeon , Bernard Decroix
Tetrahedron Letters, 1996, 37 (43), pp.7707-7710. ⟨10.1016/0040-4039(96)01738-8⟩
Journal articles hal-01218988v1
Image document

Synthesis of thieno[2′,3′(3′,4′ or 3′,2′):5,6]azepino[2,1-a]isoindolediones from N-Thienyl-2(3)-ylmethylphthalimides

Pascal Pigeon , Bernard Decroix
Journal of Heterocyclic Chemistry, 1996, 33 (1), pp.129-135. ⟨10.1002/jhet.5570330123⟩
Journal articles hal-01218990v1

Surface-functionalization with NFL peptide of Ferrocifen loaded Lipid NanoCapsules: preferential entry into human glioblastoma cells

Reatul Karim , Elise Lepeltier , Lucille Esnault , Pascal Pigeon , Laurent Lemaire
9th International Symposium on Bioorganometallic Chemistry, Aug 2019, York, United Kingdom
Conference papers hal-02617951v1

Nanoassemblies formed by polyarginine-ferrocifen conjugates for lung cancer treatment

Léna Guyon , Elise Lepeltier , Brice Calvignac , Nolwenn Lautram , Bénédicte Lelièvre
SF Nano, Dec 2018, Montpellier, France
Conference papers hal-02617897v1

Targeted-internalization of NFL-peptide functionalized lipid nanocapsules into human glioblastoma cells

Reatul Karim , Elise Lepeltier , Lucille Esnault , Pascal Pigeon , Laurent Lemaire
11 th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical, 2018, Grenade, Spain
Conference papers hal-02616018v1

Self-assembly of prodrugs formed by cell-penetrating peptide and ferrocifen for lung cancer treatment

Léna Guyon , Elise Lepeltier , Gérard Jaouen , Pascal Pigeon , Didier Perino
Imaging and therapeutic targeting in cancerology: New advances and trends in preclinical and clinical studies, 2018, Le Bono, France
Conference papers hal-02616026v1

Nanoassemblies formed by cell-penetrating peptides and ferrocifens for lung cancer treatment

Léna Guyon , Elise Lepeltier , Gérard Jaouen , Pascal Pigeon , Didier Perino
11th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 2018, Grenade, Spain
Conference papers hal-02616031v1

Surface-functionalization with NFL peptide of Lipid NanoCapsules LNC: preferential entry into human glioblastoma cells

Reatul Karim , Elise Lepeltier , Lucille Esnault , Pascal Pigeon , Laurent Lemaire
SF Nano 2017, 2017, Bordeaux, France
Conference papers hal-02616007v1

Synthesis of new polyheterocycles via N-acyliminium ion aromatic cyclization

Adam Daïch , Mohamed Othman , Pascal Pigeon , Bernard Decroix
Ve Rencontre Nationale de Chimie Hétérocyclique (5ème RNCH), May 2002, Kenitra, Morocco
Conference papers hal-02568008v1

-Cationic cyclisations of N-acyliminium ions from imide-ester functionality: Use of olefin as nucleophile

Adam Daïch , Mohamed Othman , Pascal Pigeon , Bernard Decroix
Colloque Anglo Normand de Chimie Organique (ANORCQ V), May 1999, Forges-les-Eaux, France
Conference papers hal-02568104v1

Cyclisation intramoleculaire via amidoalkylation: Synthèse de nouvelles pyrrolo(ou isoindolo)thieno[2]benzazepines et thieno[f]indolizines

Adam Daïch , Aïcha Mamouni , Pascal Pigeon , Bernard Decroix
Congrès IRCOF "Intramuros", Jun 1997, Mont-Saint-Aignan, France
Conference papers hal-02567914v1
Image document

Peptide-decorated ferrocifen lipid nanocapsules for the targeting of multidrug resistant ovarian adenocarcinoma

Andrea Bottasso , Pierre Idlas , Milad Baroud , Pascal Pigeon , Gérard Jaouen
SFNano 2022, Dec 2022, Strasbourg, France
Conference poster hal-04109714v1
Image document

Physico-chemical characterization of ferrocifen loaded lipid nanocapsules: different drug delivery systems depending on succinimido-ferrociphenol structure

Pierre Idlas , Elise Lepeltier , Pascal Pigeon , Gérard Jaouen , Catherine Passirani
SFNano2021, Annual Meeting, Dec 2021, ANGERS, France
Conference poster hal-03552215v1

Is dynamic light scattering a good method to characterize self-assemblies of cell penetrating peptide-ferrocifen conjugates?

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi
SF Nano, Dec 2019, Dijon, France
Conference poster hal-02617249v1

Synthesis and characterization of cell-penetrating peptide-ferrocifen self-assemblies

Léna Guyon , Elise Lepeltier , Jean-Christophe Gimel , Brice Calvignac , Florence Franconi
IUPAC, Jul 2019, Paris, France
Conference poster hal-02617358v1

Nanoparticules, chargées en ferrocifenes, pour le traitement du cancer du poumon par nébulisation

Léna Guyon , Elise Lepeltier , Gérard Jaouen , Pascal Pigeon , Didier Perino
12èmes journée du Cancéropôle Grand Ouest, 2018, Vannes, France. , 2018
Conference poster hal-02616022v1

Self-assemblies formed by cell-penetrating peptide and ferrocifen for lung cancer treatment

Léna Guyon , Elise Lepeltier , Gérard Jaouen , Pascal Pigeon , Didier Perino
Journée scientifique de la SFR ICAT4208, 2018, Non spécifié, France. , 2018
Conference poster hal-02616014v1

Self-assemblies consisting of cell penetrating peptides and ferrocifen for the treatment of lung carcinoma

Léna Guyon , Elise Lepeltier , Gérard Jaouen , Pascal Pigeon , Didier Perino
4th SFNano Annual Meeting, 2017, Bordeaux, France. , 2017
Conference poster hal-02615994v1