Patricia Lemarchand

90 %
Libre accès
48
Documents
Affiliation actuelle
  • ITX-lab unité de recherche de l'institut du thorax UMR1087 UMR6291 (ITX-lab)
Contact

Présentation

Patricia Lemarchand est pneumologue et professeure à Nantes Université. Ses recherches portent sur les cellules souches et leurs applications médicales. Elle enseigne aux étudiant·es en médecine la biologie cellulaire, ainsi que les différences hommes/femmes en médecine en lien avec le sexe et le genre.

Domaines de recherche

Biologie cellulaire

Publications

Publications

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Rethinking medical education through systems biology to address complexity

Laurent David , Pierre-Antoine Gourraud , Guillaume Lamirault , Patricia Lemarchand

npj Systems Biology and Applications, 2026, 12 (1), pp.12. ⟨10.1038/s41540-025-00636-5⟩

Article dans une revue inserm-05509929v1
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Increased delay to lung transplantation for women candidates: gender-based disparity matters in the lung transplant trajectory

Adrien Tissot , Anne-Sophie Coatanea , Olivia Rousseau , Antoine Roux , Benjamin Coiffard et al.

ERJ Open Research, 2025, pp.00623-2024. ⟨10.1183/23120541.00623-2024⟩

Article dans une revue inserm-04880240v1
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Understanding sex and gender disparities in COVID-19 mortality: a narrative review beyond biology

Patricia Lemarchand , Madeleine Pape , Joëlle Schwarz

Biology of Sex Differences, 2025, 16 (1), pp.76. ⟨10.1186/s13293-025-00762-z⟩

Article dans une revue inserm-05509953v1
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Questioning the Relevance of Sex Categories implemented in Medical Decision Support Systems - The Example of Pulmonary Function

Patricia Lemarchand , Dorian Hassoun , Pascale Kuntz

ESSACHESS – Journal for Communication Studies, 2024, 17 (1(33)), pp.205-229. ⟨10.21409/8253-X893⟩

Article dans une revue inserm-04653946v1

Microvascular obstruction identifies a subgroup of patients who benefit from stem cell therapy following ST-elevation myocardial infarction

Sarah Davidson , Jerome Roncalli , Daniel Surder , Roberto Corti , Atul Chugh et al.

American Heart Journal, 2023, 259, pp.79-86. ⟨10.1016/j.ahj.2023.02.004⟩

Article dans une revue inserm-04205291v1
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Generation of human induced pluripotent stem cell lines from four unrelated healthy control donors carrying European genetic background

Aurore Girardeau , Diane Atticus , Robin Canac , Bastien Cimarosti , Amandine Caillaud et al.

Stem Cell Research, 2022, 59, pp.102647. ⟨10.1016/j.scr.2021.102647⟩

Article dans une revue hal-04590823v1
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Deciphering Transcriptional Networks during Human Cardiac Development

Robin Canac , Bastien Cimarosti , Aurore Girardeau , Virginie Forest , Pierre Olchesqui et al.

Cells, 2022, 11 (23), pp.3915. ⟨10.3390/cells11233915⟩

Article dans une revue inserm-04136798v1
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Evaluation of the Post-COVID-19 Functional Status (PCFS) Scale in a cohort of patients recovering from hypoxemic SARS-CoV-2 pneumonia.

Naïla Benkalfate , Emmanuel Eschapasse , Thomas Georges , Camille Leblanc , Stéphanie Dirou et al.

BMJ open respiratory research, 2022, 9 (1), pp.e001136. ⟨10.1136/bmjresp-2021-001136⟩

Article dans une revue hal-03618379v1
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Generation of three human induced pluripotent stem cell lines with IRX5 knockout and knockin genetic editions using CRISPR-Cas9 system

Robin Canac , Amandine Caillaud , Bastien Cimarosti , Aurore Girardeau , Hanan Hamamy et al.

Stem Cell Research, 2022, 58, pp.102627. ⟨10.1016/j.scr.2021.102627⟩

Article dans une revue hal-03585527v1
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Generation of human induced pluripotent stem cell lines from three patients affected by Catecholaminergic Polymorphic ventricular tachycardia (CPVT) carrying heterozygous mutations in RYR2 gene

Bastien Cimarosti , Robin Canac , Stephan de Waard , Aurore Girardeau , Anne Gaignerie et al.

Stem Cell Research, 2022, 60, pp.102688. ⟨10.1016/j.scr.2022.102688⟩

Article dans une revue hal-04590843v1
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Generation of human induced pluripotent stem cell lines from two patients affected by catecholamine-induced QT prolongation (CIQTP)

Bastien Cimarosti , Robin Canac , Aurore Girardeau , Marine Arnaud , Quentin Francheteau et al.

Stem Cell Research, 2022, 59, pp.102649. ⟨10.1016/j.scr.2021.102649⟩

Article dans une revue hal-04590780v1
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Human model of IRX5 mutations reveals key role for this transcription factor in ventricular conduction

Zeina Al Sayed , Robin Canac , Bastien Cimarosti , Carine Bonnard , Jean-Baptiste Gourraud et al.

Cardiovascular Research, 2021, 117 (9), pp.2092-2107. ⟨10.1093/cvr/cvaa259⟩

Article dans une revue inserm-02934863v2
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A consistent arrhythmogenic trait in Brugada syndrome cellular phenotype

Zeina Al Sayed , Mariam Jouni , Jean-Baptiste Gourraud , Nadjet Belbachir , Julien Barc et al.

Clinical and Translational Medicine, 2021, 11 (6), pp.e413. ⟨10.1002/ctm2.413⟩

Article dans une revue inserm-04136802v2
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Maurocalcin and its analogue MCaE12A facilitate Ca2+ mobilization in cardiomyocytes

Stephan de Waard , Jérôme Montnach , Charly Cortinovis , Olfa Chkir , Morteza Erfanian et al.

Biochemical Journal, 2020, 477 (20), pp.3985-3999. ⟨10.1042/BCJ20200206⟩

Article dans une revue inserm-02968252v1
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Functional Impact of BeKm-1, a High-Affinity hERG Blocker, on Cardiomyocytes Derived from Human-Induced Pluripotent Stem Cells

Stephan de Waard , Jérôme Montnach , Barbara Ribeiro , Sébastien Nicolas , Virginie Forest et al.

International Journal of Molecular Sciences, 2020, 21 (19), pp.7167. ⟨10.3390/ijms21197167⟩

Article dans une revue hal-02951542v1
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Deconditioning, fatigue and impaired quality of life in long-term survivors after allogeneic hematopoietic stem cell transplantation

Stéphanie Dirou , Arnaud Chambellan , Patrice Chevallier , Patrick Germaud , Guillaume Lamirault et al.

Bone Marrow Transplantation, 2017, Epub ahead of print. ⟨10.1038/s41409-017-0057-5⟩

Article dans une revue inserm-01684314v1
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Sustained quality of life improvement after intracoronary injection of autologous bone marrow cells in the setting of acute myocardial infarction: results from the BONAMI trial

Guillaume Lamirault , Elodie de Bock , Véronique Sébille , Béatrice Delasalle , Jérôme Roncalli et al.

Quality of Life Research, 2017, 26 (1), pp.121-125. ⟨10.1007/s11136-016-1366-7⟩

Article dans une revue inserm-01350712v1
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Intramyocardial transplantation of mesenchymal stromal cells for chronic myocardial ischemia and impaired left ventricular function: Results of the MESAMI 1 pilot trial

Damien Guijarro , M Lebrin , Olivier Lairez , Philippe Bourin , Nicolas Piriou et al.

International Journal of Cardiology, 2016, ⟨10.1016/j.ijcard.2016.02.016⟩

Article dans une revue inserm-01269644v1
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Mesenchymal Stem Cells Induce Suppressive Macrophages through Phagocytosis in a Mouse Model of Asthma

Faouzi Braza , Stéphanie Dirou , Virginie Forest , Vincent Sauzeau , Dorian Hassoun et al.

STEM CELLS, 2016, ⟨10.1002/stem.2344⟩

Article dans une revue inserm-01277384v1
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HIV-Tat induces a decrease in I Kr and I Ks via reduction in phosphatidylinositol-(4,5)-bisphosphate availability

Zeineb Es-Salah-Lamoureux , Mariam Jouni , Nadjet Belbachir , Zeina Reda , Al Sayed et al.

Journal of Molecular and Cellular Cardiology, 2016, [Epub ahead of print]. ⟨10.1016/j.yjmcc.2016.08.022⟩

Article dans une revue inserm-01360585v1
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Meta-Analysis of Cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data.

Mariann Gyöngyösi , Wojciech Wojakowski , Patricia Lemarchand , Ketil Lunde , Michal Tendera et al.

Circulation Research, 2015, 116 (8), pp.1346-60. ⟨10.1161/CIRCRESAHA.116.304346⟩

Article dans une revue inserm-01261631v2
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Impact of pre-transplant diffusion lung capacity for nitric oxide (DLNO) and of DLNO/pre-transplant diffusion lung capacity for carbon monoxide (DLNO/DLCO) ratio on pulmonary outcomes in adults receiving allogeneic stem cell transplantation for hematological diseases

Amandine Le Bourgeois , Florent Malard , Patrice Chevallier , Gaxuxa Urbistandoy , Thierry Guillaume et al.

Bone Marrow Transplantation, 2015, 51 (4), pp.589 - 592. ⟨10.1038/bmt.2015.284⟩

Article dans une revue inserm-01636141v1
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Predictors of ventricular remodelling in patients with reperfused acute myocardial infarction and left ventricular dysfunction candidates for bone marrow cell therapy: insights from the BONAMI trial

Alain Manrique , Patricia Lemarchand , Béatrice Delasalle , Olivier Lairez , Catherine Sportouch et al.

European Journal of Nuclear Medicine and Molecular Imaging, 2015, ⟨10.1007/s00259-015-3279-z⟩

Article dans une revue inserm-01261620v1
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Toward Personalized Medicine: Using Cardiomyocytes Differentiated From Urine-Derived Pluripotent Stem Cells to Recapitulate Electrophysiological Characteristics of Type 2 Long QT Syndrome

Mariam Jouni , Karim Si-Tayeb , Zeineb Es-Salah-Lamoureux , Xenia Latypova , Benoite Champon et al.

Journal of the American Heart Association, 2015, pp.e002159. ⟨10.1161/JAHA.115.002159⟩

Article dans une revue inserm-01199430v1
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Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia

Karim Si-Tayeb , Salam Idriss , Benoite Champon , Amandine Caillaud , Matthieu Pichelin et al.

Disease Models & Mechanisms, 2015, ⟨10.1242/dmm.022277⟩

Article dans une revue hal-01233240v1
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Stable long-term pulmonary function after fludarabine, antithymocyte globulin and i.v. BU for reduced-intensity conditioning allogeneic SCT.

Stéphanie Dirou , Florent Malard , Arnaud Chambellan , Patrice Chevallier , Patrick Germaud et al.

Bone Marrow Transplantation, 2014, 49 (5), pp.622-7. ⟨10.1038/bmt.2014.15⟩

Article dans une revue inserm-00955626v1
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Impact of intracoronary bone marrow cell therapy on left ventricular function in the setting of ST-segment elevation myocardial infarction: a collaborative meta-analysis.

Ronak Delewi , Alexander Hirsch , Jan G. Tijssen , Volker Schächinger , Wojciech Wojakowski et al.

European Heart Journal, 2014, 35 (15), pp.989-98. ⟨10.1093/eurheartj/eht372⟩

Article dans une revue inserm-00907022v1
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Difference in mobilization of progenitor cells after myocardial infarction in smoking versus non-smoking patients: insights from the BONAMI trial.

Guillaume Lamirault , Sophie Susen , Virginie Forest , Caroline Hemont , Angelo Parini et al.

Stem Cell Research and Therapy, 2013, 4 (6), pp.152. ⟨10.1186/scrt382⟩

Article dans une revue inserm-00932365v1
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Intramyocardial delivery of mesenchymal stem cell-seeded hydrogel preserves cardiac function and attenuates ventricular remodeling after myocardial infarction.

Eva Mathieu , Guillaume Lamirault , Claire Toquet , Pierre Lhommet , Emilie Rederstorff et al.

PLoS ONE, 2012, 7 (12), pp.e51991. ⟨10.1371/journal.pone.0051991⟩

Article dans une revue inserm-00770250v1
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Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial.

Jérôme Roncalli , Frédéric Mouquet , Christophe Piot , Jean-Noël Trochu , Philippe Le Corvoisier et al.

European Heart Journal, 2011, 32 (14), pp.1748-1757. ⟨10.1093/eurheartj/ehq455⟩

Article dans une revue inserm-00543644v1
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Autologous bone marrow cells and ischemic cardiomyopathy.

Jérôme Roncalli , Patricia Lemarchand

Future Cardiology, 2011, 7 (5), pp.603-7. ⟨10.2217/fca.11.46⟩

Article dans une revue inserm-00642809v1
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Signaling by the Matrix Proteoglycan Decorin Controls Inflammation and Cancer Through PDCD4 and MicroRNA-21.

Rosetta Merline , Kristin Moreth , Janet Beckmann , Madalina V. Nastase , Jinyang Zeng-Brouwers et al.

Science Signaling, 2011, 4 (199), pp.ra75. ⟨10.1126/scisignal.2001868⟩

Article dans une revue inserm-00642810v1
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Carotid and femoral atherosclerotic plaques show different morphology.

Fanny Herisson , Marie-Françoise Heymann , Maud Chétiveaux , Céline Charrier , Séverine Battaglia et al.

Atherosclerosis, 2011, 216 (2), pp.348-54. ⟨10.1016/j.atherosclerosis.2011.02.004⟩

Article dans une revue inserm-00642808v1
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Cell distribution after intracoronary bone marrow stem cell delivery in damaged and undamaged myocardium: implications for clinical trials.

Virginie Forest , Ashok Tirouvanziam , Christian Perigaud , Sarah Fernandes , Marion Fusellier et al.

Stem Cell Research and Therapy, 2010, 1 (1), pp.4. ⟨10.1186/scrt4⟩

Article dans une revue inserm-00663767v1
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Cardiac cell therapy: overexpression of connexin43 in skeletal myoblasts and prevention of ventricular arrhythmias.

Sarah Fernandes , Harold V.M. van Rijen , Virginie F. Forest , Stéphane Evain , Anne-Laure Leblond et al.

Journal of Cellular and Molecular Medicine, 2009, 13 (9B), pp.3703-12. ⟨10.1111/j.1582-4934.2009.00740.x⟩

Article dans une revue inserm-00369695v1
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Developing cell therapy techniques for respiratory disease: intratracheal delivery of genetically engineered stem cells in a murine model of airway injury.

Anne-Laure Leblond , Patrice Naud , Virginie F. Forest , Clothilde Gourden , Christine Sagan et al.

Human Gene Therapy, 2009, 20 (11), pp.1329-43. ⟨10.1089/hum.2009.035⟩

Article dans une revue inserm-00407987v1
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Autologous myoblast transplantation after myocardial infarction increases the inducibility of ventricular arrhythmias

Sarah Fernandes , Jean-Christophe Amirault , Gilles Lande , Jean-Michel Nguyen , Virginie Forest et al.

Cardiovascular Research, 2006, 69 (2), pp.348 - 358. ⟨10.1016/j.cardiores.2005.10.003⟩

Article dans une revue inserm-01707095v1
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In vivo selective and distant killing of cancer cells using adenovirus-mediated decorin gene transfer

José Guilherme Guilherme Tralhão , Liliana Schaefer , Miroslava Micegova , César Evaristo , Elke Schönherr et al.

FASEB Journal, 2003, 17 (3), pp.464 - 466. ⟨10.1096/fj.02-0534fje⟩

Article dans une revue inserm-01707109v1

Characterization of the Role of AMP-Activated Protein Kinase in the Regulation of Glucose-Activated Gene Expression Using Constitutively Active and Dominant Negative Forms of the Kinase

Angela Woods , Dalila D. Azzout-Marniche , Marc Foretz , Silvie Stein , Patricia Lemarchand et al.

Molecular and Cellular Biology, 2000, 20 (18), pp.6704-6711. ⟨10.1128/mcb.20.18.6704-6711.2000⟩

Article dans une revue hal-02546620v1

Characterization of the role of AMP-activated protein kinase in the regulation of glucose-activated gene expression using constitutively active and dominant negative forms of the kinase.

A Woods , Dalila D. Azzout-Marniche , M Foretz , S C Stein , P Lemarchand et al.

Molecular and Cellular Biology, 2000, pp.6704-11

Article dans une revue hal-01611458v1

ADD1/SREBP-1c Is Required in the Activation of Hepatic Lipogenic Gene Expression by Glucose

Marc Foretz , Corinne Pacot , Isabelle Dugail , Patricia Lemarchand , Colette Guichard et al.

Molecular and Cellular Biology, 1999, 19 (5), pp.3760-3768. ⟨10.1128/mcb.19.5.3760⟩

Article dans une revue hal-02350031v1
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In vivo gene transfer and expression in normal uninjured blood vessels using replication-deficient recombinant adenovirus vectors.

Patricia Lemarchand , M Jones , I Yamada , R Crystal

Circulation Research, 1993, 72 (5), pp.1132-1138. ⟨10.1161/01.RES.72.5.1132⟩

Article dans une revue inserm-05117017v1

17° Entretiens de la sauvegarde - Table ronde : La vérification du passif

Mathilde Naïda Alice Dols-Magneville , Sophie Atsarias-dumas , Pierre Charlier , Patricia Lemarchand

17° Entretiens de la sauvegarde - IFPPC, IFPPC, Jan 2022, Paris (en virtuel), France

Communication dans un congrès hal-04929320v1
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Biology and medicine (beyond a biological concept of sex in health)

Patricia Lemarchand , Joelle Schwarz , Carole Clair , Madeleine Pape

Dictionnaire du genre en traduction / Dictionary of Gender in Translation / Diccionario del género en traducción., 2024

Notice d’encyclopédie ou de dictionnaire inserm-05092597v1