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Patrick MEFFRE

Professeur des universités Full professor
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Presentation

Patrick Meffre was born in Marseille, France, in 1964. After engineering studies at the Ecole Nationale Supérieure de Chimie de Paris (ENSCP, Chimie ParisTech-PSL, a member of Université Paris-Sciences et Lettres, PSL, France), he receives his Ph.D. at the Pierre and Marie Curie University (Paris) in 1991 under the supervision of Prof F. Le Goffic. After post-doctoral training with Prof S. Hanessian (Université de Montréal, Québec, Canada) he was appointed Assistant Professor at the Ecole Nationale Supérieure de Chimie de Paris in 1993. Since 2004 he moved to university of Nîmes (France) where he was appointed as Full Professor. His current interests concern : -The extraction and identification of natural products from plants including volatile organic compounds (VOCs) and their biological activity. -The synthesis of chiral or non-chiral biologically active compounds (antibacterial agents, adjuvants), of unusual amino acids, chiral synthons derived from natural amino acids and their biological activity. -The use of epiphytic plants (*Tillandsia* genus) as natural source of biologically active compounds or as biomonitors of air pollution. Patrick Meffre is Deputy Editor, *Amino Acids* journal (Springer) <https://www.springer.com/journal/726>

Research domains

Chemical Sciences Analytical chemistry Organic chemistry Medicinal Chemistry

Skills

Publications

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Recent advances in the development of bacterial response regulators inhibitors as antibacterial and/or antibiotic adjuvant agent: A new approach to combat bacterial resistance

Chaimae Majdi , Patrick Meffre , Zohra Benfodda
Bioorganic Chemistry, 2024, 150, pp.107606. ⟨10.1016/j.bioorg.2024.107606⟩
Journal articles hal-04675217v1
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Survey on the Traditional Use of Medicinal Herbs in Haiti: A Study on Knowledge, Practices, and Efficacy Prevention

Valendy Thesnor , Yvens Cheremond , Muriel Sylvestre , Patrick Meffre , Gerardo Cebrián-Torrejón
Plants, 2024, 13 (17), pp.2383. ⟨10.3390/plants13172383⟩
Journal articles hal-04689090v1
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Synergistic effect of tryptamine-urea derivatives to overcome the chromosomally-mediated colistin resistance in Klebsiella pneumoniae

Chaimae Majdi , Jean Dessolin , David Bénimélis , Catherine Dunyach-Rémy , Alix Pantel
Bioorganic and Medicinal Chemistry, 2024, 100, pp.117604. ⟨10.1016/j.bmc.2024.117604⟩
Journal articles hal-04419733v1
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Investigation of PhoP Response Regulator inhibition to overcome resistance in Gram-negative clinical bacteria

Chaimae Majdi , Valentin Duvauchelle , Mohamed Seghir , David Bénimélis , Catherine Dunyach-Rémy
International Journal of Antimicrobial Agents, 2024, 64 (4), pp.107298. ⟨10.1016/j.ijantimicag.2024.107298⟩
Journal articles hal-04674063v1
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Determination of the maximum bioaccumulation capacity of various metals in leaves of two Tillandsia species

Alexandre Gonzalez , Zohra Benfodda , David Bénimélis , Damien Bourgeois , Damien Herfurth
Environmental Science and Pollution Research, inPress, ⟨10.1007/s11356-024-33183-3⟩
Journal articles hal-04535649v1
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Volatile Organic Compounds Emitted by Flowers: Ecological Roles, Production by Plants, Extraction, and Identification

Mame-Marietou Lo , Zohra Benfodda , Roland Molinié , Patrick Meffre
Plants, 2024, 13 (3), pp.417. ⟨10.3390/plants13030417⟩
Journal articles hal-04430391v1
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Characterization of Alginates of Sargassum from the Archipelago of Guadeloupe

Naika Marcin , Valendy Thesnor , Valentin Duvauchelle , Alejandro Ponce-Mora , Lucia Gimeno-Mallench
Separations, 2024, 11 (8), pp.226. ⟨10.3390/separations11080226⟩
Journal articles hal-04689192v1

Synthesis of amino juglone derivatives with adjuvant activity against clinical isolated methicillin-resistant staphylococcus aureus strains

Chaimae Majdi , Mohamed Seghir , Yehan Wegrich , Djilali Behilil , David Bénimélis
Bioorganic Chemistry, 2024, 150, pp.107627. ⟨10.1016/j.bioorg.2024.107627⟩
Journal articles hal-04689127v1
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Phytochemical and Biological Study of Trophic Interaction between Pseudosphinx Tetrio L. Larvae and Allamanda Cathartica L.

Linda Matignon , Mame Marietou Lo , Magneric Monpierre , Mauro Vicentini Correia , Drochss Pettry Valencia
Plants, 2023, 12 (3), pp.520. ⟨10.3390/plants12030520⟩
Journal articles hal-04099507v1
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An overview on the antibacterial properties of juglone, naphthazarin, plumbagin and lawsone derivatives and their metal complexes

Chaimae Majdi , Valentin Duvauchelle , Patrick Meffre , Zohra Benfodda
Biomedicine and Pharmacotherapy, 2023, 162, pp.114690. ⟨10.1016/j.biopha.2023.114690⟩
Journal articles hal-04100606v1
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β-cell–specific E2f1 deficiency impairs glucose homeostasis, β-cell identity, and insulin secretion

Frédérik Oger , Cyril Bourouh , Marika Elsa Friano , Emilie Courty , Laure Rolland
Diabetes, 2023, 72 (8), pp.1112-1126. ⟨10.2337/db22-0604⟩
Journal articles hal-04200339v1

Enzyme inhibitors for drug discovery

Patrick Meffre , Zohra Benfodda , Sébastien Albrecht
Amino Acids, 2023, 65, ⟨10.1007/s00726-023-03357-3⟩
Journal articles hal-04320815v1
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Antibacterial Activity and Untargeted Metabolomics Profiling of Acalypha arvensis Poepp

V. Thesnor , Roland Molinié , Ryland Giebelhaus , A. Paulina de la Mata Espinosa , James Harynuk
Molecules, 2023, 28 (23), pp.7882. ⟨10.3390/molecules28237882⟩
Journal articles hal-04419754v1
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Microwave-assisted synthesis of new environmentally friendly biodegradable and antibacterial heterocycles

Miyanou Rosales-Hurtado , Valentin Duvauchelle , David Bénimélis , Maya Ogawa-Okada , Naofumi Yamamoto
Environmental Chemistry Letters, 2022, ⟨10.1007/s10311-022-01522-w⟩
Journal articles hal-03805578v1
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Isolation and Identification of Flavones Responsible for the Antibacterial Activities of Tillandsia Bergeri Extracts.

Mame-Marietou Lo , Zohra Benfodda , Catherine Dunyach-Rémy , David Bénimélis , Romain Roulard
ACS Omega, 2022, 7 (40), pp.35851--35862. ⟨10.1021/acsomega.2c04195⟩
Journal articles hal-03823329v1
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Catalyst-Free Site Selective Hydroxyalkylation of 5-Phenylthiophen-2-amine with α-Trifluoromethyl Ketones through Electrophilic Aromatic Substitution

Valentin Duvauchelle , David Bénimélis , Patrick Meffre , Zohra Benfodda
Molecules, 2022, 27 (3), pp.925. ⟨10.3390/molecules27030925⟩
Journal articles hal-03550954v1
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Extraction and Identification of Volatile Organic Compounds in Scentless Flowers of 14 Tillandsia Species Using HS-SPME/GC-MS

Alexandre Gonzalez , Zohra Benfodda , David Bénimélis , Jean-Xavier Fontaine , Roland Molinié
Metabolites, 2022, 12 (9), pp.628. ⟨10.3390/metabo12070628⟩
Journal articles hal-03725030v1
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The transcription factor E2F1 controls the GLP-1 receptor pathway in pancreatic β cells

Cyril Bourouh , Emilie Courty , Laure Rolland , Gianni Pasquetti , Xavier Gromada
Cell Reports, 2022, 40 (6), pp.111170. ⟨10.1016/j.celrep.2022.111170⟩
Journal articles hal-03810743v1
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Recent contribution of medicinally active 2-aminothiophenes: a privileged scaffold for drug discovery

Valentin Duvauchelle , Patrick Meffre , Zohra Benfodda
European Journal of Medicinal Chemistry, 2022, ⟨10.1016/j.ejmech.2022.114502⟩
Journal articles hal-03798762v1
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Green methodologies for the synthesis of 2-aminothiophene

Valentin Duvauchelle , Patrick Meffre , Zohra Benfodda
Environmental Chemistry Letters, 2022, ⟨10.1007/s10311-022-01482-1⟩
Journal articles hal-03798752v1
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Evaluation of Knowledge and Risk Perception about Antibiotic Resistance in Biology and Mathematics Young Students in Nîmes University in France

Valentin Duvauchelle , Elsa Causse , Julien Michon , Patrick Rateau , Karine Weiss
International Journal of Environmental Research and Public Health, 2021, 18 (18), pp.9692. ⟨10.3390/ijerph18189692⟩
Journal articles hal-03344418v1
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Synthesis, Structure Elucidation, Antibacterial Activities, and Synergistic Effects of Novel Juglone and Naphthazarin Derivatives Against Clinical Methicillin-Resistant Staphylococcus aureus Strains

Valentin Duvauchelle , Chaimae Majdi , David Bénimélis , Catherine Dunyach-Remy , Patrick Meffre
Frontiers in Chemistry, 2021, 9, ⟨10.3389/fchem.2021.773981⟩
Journal articles hal-03446358v1
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Extraction and Identification of Volatile Organic Compounds Emitted by Fragrant Flowers of Three Tillandsia Species by HS-SPME/GC-MS

Mame-Marietou Lo , Zohra Benfodda , David Bénimélis , Jean-Xavier Fontaine , Roland Molinié
Metabolites, 2021, 11 (9), pp.594. ⟨10.3390/metabo11090594⟩
Journal articles hal-03334373v1
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Development of a HS-SPME/GC-MS Method for the Extraction and Identification of the Volatile Compounds Emitted by Flowers of Tillandsia xiphioides

Mame-Marietou Lo , Zohra Benfodda , David Bénimélis , Jean-Xavier J.-X. Fontaine , Roland Molinié
ACS Omega, 2021, 6 (19), pp.12691-12698. ⟨10.1021/acsomega.1c00917⟩
Journal articles hal-03243914v1

Synthesis of histidine kinase inhibitors and their biological properties

Miyanou Rosales-Hurtado , Patrick Meffre , Hendrik Szurmant , Zohra Benfodda
Medicinal Research Reviews, 2019, ⟨10.1002/med.21651⟩
Journal articles hal-02400521v1
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Improved synthesis, resolution, absolute configuration determination and biological evaluation of HLM006474 enantiomers

Miyanou Rosales-Hurtado , Alexandre Lebeau , Cyril Bourouh , Gerardo Cebrian Cebrian-Torrejon , Muriel Albalat
Bioorganic and Medicinal Chemistry Letters, 2019, 29, pp.380-382. ⟨10.1016/j.bmcl.2018.12.037⟩
Journal articles hal-01968387v1
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Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update. Part II: synthetic uses of ethynylglycine synthon

Zohra Benfodda , David Bénimélis , Gianna Reginato , Patrick Meffre
Amino Acids, 2018, 50 (10), pp.1307-1328. ⟨10.1007/s00726-018-2628-1⟩
Journal articles hal-01859944v1
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Synthesis of 1,4-disubstituted 1,2,3-triazole Derivatives Using Click Chemistry and their Src Kinase Activities

Alexandre Lebeau , Cyril Abrioux , David Bénimèlis , Zohra Benfodda , Patrick Meffre
Medicinal Chemistry, 2017, Medicinal Chemistry, 13, pp.40-48. ⟨10.2174/1573406412666160404125718⟩
Journal articles hal-01495029v1
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Spatial distribution of triazine residues in a shallow alluvial aquifer linked to groundwater residence time

Lara Sassine , Corinne Le Gal La Salle , Mahmoud Khaska , Patrick Verdoux , Patrick Meffre
Environmental Science and Pollution Research, 2017, 24 (8), pp.6878-6888. ⟨10.1007/s11356-016-7224-x⟩
Journal articles hal-01544262v1
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Synthesis of a Novel Rhizobitoxine-Like Triazole-Containing Amino Acid

Thibaut Boibessot , David Bénimélis , Marion Jean , Zohra Benfodda , Patrick Meffre
SYNLETT, 2016, 27 (19), pp.2685-2688. ⟨10.1055/s-0036-1588300⟩
Journal articles hal-01404310v1
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The Rational Design, Synthesis, and Antimicrobial Properties of Thiophene Derivatives That Inhibit Bacterial Histidine Kinases

Thibaut Boibessot , Christopher Zschiedrich , Alexandre Lebeau , David Bénimélis , Catherine Dunyach-Remy
Journal of Medicinal Chemistry, 2016, 59, pp.8830-8847. ⟨10.1021/acs.jmedchem.6b00580⟩
Journal articles hal-01543599v1
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Advances in the synthesis of α‑quaternary α‑ethynyl α‑amino acids

Thibaut Boibessot , David Bénimélis , Patrick Meffre , Zohra Benfodda
Amino Acids, 2016, 48 (9), pp.2081-2101. ⟨10.1007/s00726-016-2276-2⟩
Journal articles hal-01540958v1
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Ethynylglycine synthon, a useful precursor for the synthesis of biologically active compounds: an update

Zohra Benfodda , David Bénimélis , Gianna Reginato , Patrick Meffre
Amino Acids, 2015, 47 (2), pp.271-279. ⟨10.1007/s00726-014-1902-0⟩
Journal articles hal-01676812v1
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Synthesis, resolution, and determination of absolute configuration of protected α-ethynylphenylalanine enantiomers

Z Benfodda , David Bénimèlis , Marion Jean , Jean-Valère Naubron , Valerie Rolland
Amino Acids, 2015, 47 (5), pp.899-907. ⟨10.1007/s00726-015-1917-1⟩
Journal articles hal-02002634v1

Synthesis of cis-5-Trifluoromethylproline from L-Glutamic Acid

Stéphanie Ortial , Rajesh Dave , Zohra Benfodda , David Bénimélis , Patrick Meffre
SYNLETT, 2013, 2014 (25), pp.0569-0573. ⟨10.1055/s-0033-1340553⟩
Journal articles hal-00969187v1
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Chemoenzymatic routes to enantiomerically pure 2-azatyrosine and 2-, 3- and 4-pyridylalanine derivatives

Amer Moussa , Patrick Meffre , Jean Martinez , Valérie Rolland
Amino Acids, 2012, 42, pp.1339-1348. ⟨10.1007/s00726-010-0829-3⟩
Journal articles hal-00616942v1
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NEW ROUTES TO a-AMINO ACID b,g-THIOENOL ETHER DERIVATIVES

Patrick Meffre , Patrick Mcffrc , Philippe Durand
Synthetic Communications, 2006, 32 (2), pp.287-296
Journal articles hal-02002695v1
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New unsaturated amino acids containing an allylsilane moiety on the lateral chain

Gianna Reginato , Alessandro Mordini , Patrick Meffre , Alice Tenti , Michela Valacchi
Tetrahedron: Asymmetry, 2006, 17 (6), pp.922-926. ⟨10.1016/j.tetasy.2006.02.017⟩
Journal articles hal-02002619v1
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Ethynylglycine synthon from Garner's aldehyde: a useful precursor for the synthesis of non-natural amino acids

G. Reginato , Patrick Meffre , F. Gaggini
Amino Acids, 2005, 29 (2), pp.81-87. ⟨10.1007/s00726-005-0184-y⟩
Journal articles hal-02002665v1
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γ-Fluorinated analogues of glutamic acid and glutamine

R. Dave , B. Badet , Patrick Meffre
Amino Acids, 2003, 24 (3), pp.245-261. ⟨10.1007/s00726-002-0410-9⟩
Journal articles hal-02002676v1

Practical one-step synthesis of ethynylglycine synthon from Garner's aldehyde

Patrick Meffre , Sébastien Hermann , Philippe Durand , Gianna Reginato , Antonella Riu
Tetrahedron, 2002, 58 (25), pp.5159-5162. ⟨10.1016/S0040-4020(02)00438-6⟩
Journal articles hal-02002686v1

A concise synthesis of l-4,4-difluoroglutamine

Patrick Meffre , Rajesh Dave , Jacques Leroy , Bernard Badet
Tetrahedron Letters, 2001, 42 (49), pp.8625-8627. ⟨10.1016/S0040-4039(01)01866-4⟩
Journal articles hal-02002782v1

Chemoenzymatic synthesis of enantiopure 1,1′-disubstituted ferrocenyl aminoalcohols

Lars Veum , Hélène Brouard , Patrick Meffre , Marc Larchevêque , Didier Buisson*
Tetrahedron: Asymmetry, 2000, 11 (20), pp.4055-4059
Journal articles hal-02002779v1

Syntheses of optically active 2-amino-4-oxobutyric acid and N,O-protected derivatives

Patrick Meffre
Amino Acids, 1999, 16 (3-4), pp.251-272
Journal articles hal-02002777v1

METHYL (S)-2-PHTHALIMIDO-4-OXOBUTANOATE

Patrick Meffre , Philippe Durand , François Le Goffic
Organic Syntheses : An annual publication of satisfactory methods for the preparation of organic chemicals, 1999, 76, pp.123
Journal articles hal-02002772v1

Synthesis of New Chiral Vinyl Halides from L-Serinal

Eric Branquet , Patrick Meffre , Philippe Durand , François Le Goffic
Synthetic Communications, 1998, 28 (4), pp.613-622
Journal articles hal-02002767v1

β,γ-Alkynylα-amino acids: a synthetic challenge

Patrick Meffre , F. Le Goffic
Amino Acids, 1996, 11 (3-4), pp.313-328
Journal articles hal-02002756v1

Synthesis of optically active β,γ-alkynylglycine derivatives

Patrick Meffre , Laurence Gauzy , Eric Branquet , Philippe Durand , François Le Goffic
Tetrahedron, 1996, 52 (34), pp.11215-11238
Journal articles hal-02002738v1

Straightforward Synthesis of Optically Pure Methyl (S)-2-Phthalimido-4-oxobutanoate and Some of Its Acetal and Thioacetal Derivatives

Patrick Meffre , Philippe Durand , François Le Goffic
Synthesis: Journal of Synthetic Organic Chemistry, 1995, 1995 (09), pp.1111-1114
Journal articles hal-02002741v1

En route to optically active ethynylglycine derivatives

Patrick Meffre , Laurence Gauzy , Chantal Perdigues , Florence Desanges-Levecque , Eric Branquet
Tetrahedron Letters, 1995, 36 (6), pp.877-880
Journal articles hal-02010594v1

A Straightforward Synthesis of N-Boc-L-serinal and N-Boc-L-threoninal Acetonides

Patrick Meffre , Philippe Durand , Eric Branquet , Fran°cois Le Goffic
Synthetic Communications, 1994, 24 (15), pp.2147-2152
Journal articles hal-02002737v1

Asymmetric dihydroxylation of olefins with a simple chiral ligand

Stephen Hanessian , Patrick Meffre , Mario Girard , Serge Beaudoin , Jean Yves Sanceau
Journal of Organic Chemistry, 1993, 58 (8), pp.1991-1993
Journal articles hal-02002729v1

A new class of unusual α-aminoacids : α-aminoacid β,γ-enol thioethers

Patrick Meffre , L. Vo-Quang , Y. Vo-Quang , F. Le Goffic
Tetrahedron Letters, 1991, 32 (36), pp.4717-4720. ⟨10.1016/S0040-4039(00)92290-1⟩
Journal articles hal-02010629v1

A new class of unusual α-aminoacids : α-aminoacid β,γ-enol thioethers

Patrick Meffre , H. Lhermitte , L. Vo-Quang , Y. Vo-Quang , F. Le Goffic
Tetrahedron Letters, 1991, 32 (36), pp.4717-4720. ⟨10.1016/S0040-4039(00)92290-1⟩
Journal articles hal-02002724v1

Unusual α-aminoacids from vinylglycine

Patrick Meffre , L. Vo-Quang , Y. Vo-Quang , F. Le Goffic
Tetrahedron Letters, 1990, 31 (16), pp.2291-2294. ⟨10.1016/0040-4039(90)80209-5⟩
Journal articles hal-02002721v1

Unusual α-aminoacids from vinylglycine

Patrick Meffre , L. Vo-Quang , Y. Vo-Quang , F. Le Goffic
Tetrahedron Letters, 1990, 31 (16), pp.2291-2294. ⟨10.1016/0040-4039(90)80209-5⟩
Journal articles hal-02010624v1

N-(Benzyloxycarbonyl)-L-vinylglycike Methyl Ester from L-Methionine Methyl Ester Hydrochloride

Patrick Meffre , Liliane Vo-Quang , Yen Vo-Quang , François Le Goffic
Synthetic Communications, 1989, 19 (20), pp.3457-3468
Journal articles hal-02002719v1

Analysis of the Volatile Organic Compounds of Tillandsia flowers by HS-SPME/GC-MS

Alexandre Gonzalez , Zohra Benfodda , David Bénimélis , Jean-Xavier J.-X. Fontaine , Roland Molinié
Analytics 2022, Sep 2022, Nantes, France
Conference papers hal-03806502v1

E2f1 contrôle la fonction et l’identité de la cellule beta pancréatique par un mécanisme dépendant des enzymes HDAC

Cyril Bourouh , Frédérik Oger , Xavier Gromada , Maeva Moreno , Charlène Carney
Congrès de la Société Francophone du Diabète 2021, SFD, Mar 2021, Strasbourg (100% virtuel), France
Conference papers hal-04461303v1

Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases

Zohra Benfodda , Miyanou Rosales-Hurtado , Thibaut Boibessot , Christopher Zschiedrich , Alexandre Lebeau
2nd international conference Antimicrobial and antibacterial Istanbul Turkey, Nov 2019, Istanbul, Turkey
Conference papers hal-02400581v1

Rational design, synthesis and antimicrobial properties of thiophene derivatives that inhibit bacterial histidine kinases

Zohra Benfodda , Thibaut Boibessot , Christopher Zschiedrich , Alexandre Lebeau , David Bénimèlis
24th ISCB international conference-Frontier research in chemistry&biology interface, Jan 2018, JAIPUR, India
Conference papers hal-01998540v1

Synthesis of 5-trifluoromethylproline from L-glutamic acid

Stéphanie Ortial , Rajesh Dave , Zohra Benfodda , David Bénimèlis , Patrick Meffre
14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Wien, Austria. pp.615-636, ⟨10.1007/s00726-015-2160-5⟩
Conference papers hal-02010135v1

Addendum to Abstracts presented at the 14th International Congress on Amino Acids, Peptides and Proteins

Patrick Meffre , Zohra Benfodda , David Bénimèlis , Stéphanie Ortial , Valerie Rolland
14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienna, Austria. pp.615-636
Conference papers hal-02002708v1

Synthesis of acetylenic analogue of phenylalanine.

Zohra Benfodda , Stéphanie Ortial , David Bénimélis , Valerie Rolland , Patrick Meffre
13th International Congress on Amino acids, peptides and proteins, Oct 2013, Galvestion (Texas), United States. pp.611, ⟨10.1007/s00726-013-1540-y⟩
Conference papers hal-00993416v1

New developments in the synthesis of acetylenic analogues of glutamate

Patrick Meffre , Zohra Benfodda , David Bénimélis , Valérie Rolland , Francine C. Acher
12 th International Congress on Amino Acids, Peptides and Proteins, Aug 2011, Beijing, China. pp.S79, ⟨10.1007/s00726-011-0955-6⟩
Conference papers hal-00621161v1

Synthesis of acetylenic analogues of glutamate

Zohra Benfodda , David Bénimèlis , Patrick Meffre , Francine C. Acher
10th International Congress on amino acids and proteins, Aug 2007, Kallithea, Greece
Conference papers hal-01998510v1

Synthesis of acetylenic analogues of glutamate

Patrick Meffre , Zohra Benfodda , David Bénimèlis , Guillaume Vierling , Francine C. Acher
10th International Congress on Amino Acids and Proteins (ICAAP), Aug 2007, Kalithea, Chalkidiki, Greece. pp.I-LXX, ⟨10.1007/s00726-007-0578-0⟩
Conference papers hal-02010124v1

New developments in the synthesis of fluorinated analogues of glutamic acid and glutamine

Patrick Meffre , Rajesh Dave , Bernard Badet
8th International Congress on Aminoacids, Sep 2003, Roma, Italy. pp.111-204, ⟨10.1007/s00726-003-0037-5⟩
Conference papers hal-02010117v1

Synthesis and biological evaluation of optically active fluorinated analogues of glutamine

Patrick Meffre , Rajesh Dave , Bernard Badet
7th International Congress on Amino Acids and Proteins, Aug 2001, Wien, Austria. pp.1-90, ⟨10.1007/s007260170030⟩
Conference papers hal-02010112v1

Synthesis of optically active fluorinated analogues of glutamic acid and glutamine with potential biological activity

Patrick Meffre , Jacques Leroy , Bernard Badet
6th International Congress on Amino Acids, Aug 1999, Bonn, Germany. pp.1-129, ⟨10.1007/BF01362415⟩
Conference papers hal-02010105v1

Synthesis and uses of aspartaldehyde derivatives

Patrick Meffre
5th International Congress on Aminoacids, Aug 1997, Kalithea, Chalkidiki, Greece. pp.25-89, ⟨10.1007/BF01373046⟩
Conference papers hal-02010098v1

New developments in the synthesis of optically active ethynylglycine derivatives

Patrick Meffre
4th International Congress on Aminoacids, Aug 1995, Wien, Austria. ⟨10.1007/BF00811751⟩
Conference papers hal-02010089v1

Different aspects of synthetic approaches including enzymatic enantioselective synthesis of aminoacids

Patrick Meffre , François Le Goffic
3rd International Congress on Aminoacids, Aug 1993, Wien, Austria. ⟨10.1007/BF00806197⟩
Conference papers hal-02010087v1
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Study of the bio monitoring potential of acclimated Tillandsia species in Occitanie for metal air pollution

Alexandre Gonzalez , Patrick Meffre
Natural Products and Biocontrol 2022, Sep 2022, Perpignan, France
Conference poster hal-03806423v1
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Synergistic Effects of Novel Naphthoquinone Derivatives Against Clinical Methicilin-Resistant Staphylococcus aureus Strain

Valentin Duvauchelle , Chaimae Majdi , David Bénimélis , Catherine Dunyach-Rémy , Patrick Meffre
REncontres en Chimie Organique Biologique 18 (RECOB18), Mar 2022, Aussois, France.
Conference poster hal-03700525v1
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Synthesis and biological evaluations of new families of histidine kinases inhibitors

Valentin Duvauchelle , Miyanou Rosales-Hurtado , Thibaut Boibessot , David Bénimèlis , Catherine Dunyach-Remy
GSO-JMJC-JED2019, Oct 2019, Montpellier, France.
Conference poster hal-02333120v1

Trophic interactions between Pseudosphinx tetrio larvae and Allamanda cathartica

Linda Matignon , Mame Marietou Lo , Antonio Doménech-Carbó , Muriel Sylvestre , Patrick Meffre
Caribbean Science and Innovation Meeting 2019, Oct 2019, Pointe-à-Pitre (Guadeloupe), France
Conference poster hal-02893707v1
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Synthesis of thiophene derivatives: Potential new inhibitors of histidine kinases

Miyanou Rosales-Hurtado , Thibaut Boibessot , Christopher Zschiedrich , Alexandre Lebeau , David Bénimélis
Rencontres en Chimie Organique Biologique (Recob 17), Mar 2018, Aussois, France.
Conference poster hal-01997587v1

Design and synthesis of novel HLM 006474 derivatives.

Zohra Benfodda , Gerardo Cebrian Cebrian-Torrejon , Bourguet Romane , Sciortino Giuseppe , Jean-Didier Maréchal
24th ISCB international conference-Frontier research in chemistry&biology interface., Jan 2018, JAIPUR, India
Conference poster hal-01998366v1

Improved synthesis, resolution, absolute configuration determination of HLM006474 enantiomer

Patrick Meffre , Miyanou Rosales-Hurtado , Alexandre Lebeau , Gerardo Cebrian Cebrian-Torrejon , Muriel Albalat
XXII International conférence on Organic synthesis (22-ICOS), Sep 2018, Florence, Italy
Conference poster hal-02011288v1

Synthesis of Novel Triazole Amino Acids Analogues of Natural Amino Acids

Patrick Meffre , Thibaut Boibessot , David Bénimèlis , Zohra Benfodda
20th European symposium on Organic Chemistry (ESOC), Jul 2017, Cologne, Germany
Conference poster hal-02011261v1

Rational design of potent histidine kinase inhibitors with antimicrobial activities.

Zohra Benfodda , Christopher Zschiedrich , Alexandre Lebeau , Thibaut Boibessot , Marta Maria Perego
Experimental Biology meeting in San Diego, Apr 2016, San Diego, United States. The FASEB Journal, 30 (S1), pp.lb146-lb146, ⟨10.1096/fasebj.30.1_supplement.lb146⟩
Conference poster hal-01998350v1

Design and synthesis of 1,4-disubstituted 1,2,3-triazole derivatives as Histidine Kinase inhibitor.

Zohra Benfodda , Alexandre Lebeau , David Bénimèlis , Hendrik Szurmant , Patrick Meffre
77th Harden Conference: Two Component Signalling in Bacteria: Integrating Approaches and Science, Aug 2015, Warwickshire, United Kingdom
Conference poster hal-01998338v1

Synthesis of triazole amino acids

Zohra Benfodda , Thibaut Boibessot , Alexandre Lebeau , David Bénimèlis , Patrick Meffre
14th International Congress on Amino Acids, Peptides and Proteins, Aug 2015, Vienne, Austria
Conference poster hal-01998273v1

Rational design of potent histidine kinase inhibitors with antimicrobial activities

Zohra Benfodda , Christopher Zschiedrich , Alexandre Lebeau , Thibaut Boibessot , Patrick Meffre
8ème congrès international sur les microorganismes gram-positive, Jun 2015, Montecatini, Italy
Conference poster hal-01998292v1

Synthesis of ethynyl phenylalanine

Zohra Benfodda , David Benimelis , Valerie Rolland , Thibaut Boibessot , Patrick Meffre
21ème journée de l’Institut de Recherche Pierre Fabre (IRPF) de chimie. Chambre de commerce et d’industrie de Castres, Sep 2014, Castres, France
Conference poster hal-01998205v1

Synthesis of ethynyl phenylalanine

Zohra Benfodda , David Bénimèlis , Valérie Rolland , Patrick Meffre
The 5th European Chemistry Congress, Aug 2014, Istanbul, Turkey
Conference poster hal-01998193v1

Synthetic uses of methionine

Patrick Meffre , Liliane Vo-Quang , Yen Vo-Quang , François Le Goffic
Amino Acid Derivatives : A Practical Approach, Ed. G. C. Barrett, The Practical Approach in Chemistry Series (Series Editors : L. M. Harwood, C. J. Moody), Oxford University Press, Dec. 1999, ISBN0198558538., 1999
Book sections hal-02010083v1

Synthetic uses of serine, threonine and cysteine

Patrick Meffre , Liliane Vo-Quang , Yen Vo-Quang , François Le Goffic
Amino Acid Derivatives : A Practical Approach, Ed. G. C. Barrett, The Practical Approach in Chemistry Series (Series Editors : L. M. Harwood, C. J. Moody), Oxford University Press, Dec. 1999, ISBN0198558538, 1999
Book sections hal-02010084v1