Patrizia Giannoni

Patrizia Giannoni MCF Biologie HC, HDR, Codirectrice UPR CHROME, Chargée de mission "Aide à la réussite"
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Documents
Affiliation actuelle
  • Nîmes Université (UNIMES)
Identifiants chercheurs
Contact

Présentation

EDUCATION

**2022 **HDR délivré par l'Université de Nîmes, France

**2008 Doctorat ès Pharmacologie et Toxicologie délivré par l'Université de Florence, Italie

**2004 Doctorat ès Pharmacie cum laude délivré par l'Université de Florence, Italie

PARCOURS PROFESSIONNEL

**2018- present Maître de conférences; Université de Nimes, Equipe Chrome (EA7352), Nimes, France

**2016- 2018 ATER en biologie; Université de Nimes, Equipe Chrome (EA7352), Nimes, France

**2011-2016 Stage post-doctoral; Institut de Génomique Fonctionnelle (IGF), Montpellier, France

2008-2011 Stage post-doctoral; New York University Medical center, New York, NY, USA

activités d’edition **Editeur pour **: Frontiers in Aging Neuroscience (IF=4.5)

https://www.frontiersin.org/research-topics/8864/identification-of-multiple-targets-in-the-fight-against-alzheimers-disease

https://www.frontiersin.org/research-topics/19199/environmental-clues-to-brain-disease

Editeur invité pour: · Journal of Clinical Medicine (4.241) https://www.mdpi.com/journal/jcm/special_issues/alzheimer_disease_blueprints_and_therapeutic_hints).

-Experte scientifique (reviewer) pour:

Molecules, Brain Sciences, Toxines, Journal of Clinical Medicine, Neuroscience, Journal of Neuroscience Research, International Journal of Molecular Sciences, Biomolecules, Psychopharmacology, Nutrients, Medicina, Pharmaceutics, Microorganisms, International Journal of Environmental Research and Public Health, Ecotoxicology and Environmental Safety

https://publons.com/researcher/1234310/patrizia-giannoni/

Domaines de recherche

Bactériologie Sciences cognitives Neurobiologie Biologie moléculaire Milieux et Changements globaux Neurosciences

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Publications

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The same but different: impact of animal facility sanitary status on a transgenic mouse model of Alzheimer’s disease

Caroline Ismeurt-Walmsley , Patrizia Giannoni , Florence Servant , Linda-Nora Mekki , Kevin Baranger et al.

mBio, In press, 16 (5), pp.e0400124. ⟨10.1128/mbio.04001-24⟩

Article dans une revue hal-05049573v1
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Effects of environmental concentrations of toxins BMAA and its isomers DAB and AEG on zebrafish larvae

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni

Ecotoxicology and Environmental Safety, 2024, 285, ⟨10.1016/j.ecoenv.2024.117045⟩

Article dans une revue hal-04706427v1

Brine shrimp Artemia salina to evaluate the impact of environmental concentrations of BMAA and isomers, DAB and AEG, via mortality (nauplii) and behavioural (adult) tests

Jeanne Lichtfouse , L. Lécluse , A. Demelier , P. Giannoni

Science of the Total Environment, 2024, 957, pp.177521. ⟨10.1016/j.scitotenv.2024.177521⟩

Article dans une revue hal-04868626v1
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Editorial: Environmental clues to brain disease

Patrizia Giannoni , Federica Bertaso , Gustavo Provensi

Frontiers in Aging Neuroscience, 2023, 15, pp.1220484. ⟨10.3389/fnagi.2023.1220484⟩

Article dans une revue hal-04136217v1

Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk

Audrey Courtier , Damien Potheret , Patrizia Giannoni

Life Sciences, 2022, 304, pp.120689. ⟨10.1016/j.lfs.2022.120689⟩

Article dans une revue hal-04064228v1
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Donecopride, a Swiss army knife with potential interest against Alzheimer's disease

Christophe Rochais , Cédric Lecoutey , Katia Hamidouche , Patrizia Giannoni , Florence Gaven et al.

British Journal of Pharmacology, In press, 177 (9), pp.1988-2005. ⟨10.1111/bph.14964⟩

Article dans une revue hal-02428730v1
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Editorial: Identification of Multiple Targets in the Fight Against Alzheimer's Disease

Patrizia Giannoni , Silvia Fossati , Elena Marcello , Sylvie Claeysen

Frontiers in Aging Neuroscience, 2020, 12, pp.169. ⟨10.3389/fnagi.2020.00169⟩

Article dans une revue hal-02871844v1
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Peripheral Routes to Neurodegeneration: Passing Through the Blood–Brain Barrier

Patrizia Giannoni , Sylvie Claeysen , Francesco Noe , Nicola Marchi

Frontiers in Aging Neuroscience, 2020, 12, pp.3. ⟨10.3389/fnagi.2020.00003⟩

Article dans une revue hal-02465771v1
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Development of a DGGE method to explore Legionella communities

Sandrine Bayle , B Martinez-Arribas , S. Jarraud , Patrizia Giannoni , L Garrelly et al.

Heliyon, 2020, 6 (1), pp.e03149. ⟨10.1016/j.heliyon.2019.e03149⟩

Article dans une revue hal-02430628v1
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The pericyte–glia interface at the blood–brain barrier

Patrizia Giannoni , Jerome Badaut , Cyril Dargazanli , Alexis Fayd'Herbe de Maudave , Wendy Klement et al.

Clinical Science, 2018, 132 (3), pp.361-374. ⟨10.1042/CS20171634⟩

Article dans une revue hal-02074159v1
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Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease

Kévin Baranger , Patrizia Giannoni , Stéphane Girard , Sarah Girot , Florence Gaven et al.

Neuropharmacology, 2017, 126, pp.128-141. ⟨10.1016/j.neuropharm.2017.08.031⟩

Article dans une revue hal-01799428v1
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Cerebrovascular pathology during the progression of experimental Alzheimer's disease

Patrizia Giannoni , Margarita Arango-Lievano , Ines das Neves , Marie-Claude Rousset , Kévin Baranger et al.

Neurobiology of Disease, 2016, 88, pp.107-117. ⟨10.1016/j.nbd.2016.01.001⟩

Article dans une revue hal-01477817v1

In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

Farron Mcintee , Patrizia Giannoni , Steven Blais , George Sommer , Thomas Neubert et al.

Frontiers in Aging Neuroscience, 2016, 8, ⟨10.3389/fnagi.2016.00223⟩

Article dans une revue hal-01705732v1
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Longitudinal in vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Margarita Arango-Lievano , Patrizia Giannoni , Sylvie Claeysen , Nicola Marchi , Freddy Jeanneteau

Journal of visualized experiments : JoVE, 2016, ⟨10.3791/54796⟩

Article dans une revue hal-02368047v1
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The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

Silvia Fossati , Patrizia Giannoni , Maria E Solesio , Sarah L Cocklin , Erwin Cabrera et al.

Neurobiology of Disease, 2016, 86, pp.29-40. ⟨10.1016/j.nbd.2015.11.006⟩

Article dans une revue hal-01997866v1
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Serotonin: a new hope in Alzheimer's disease?

Sylvie Claeysen , Joël Bockaert , Patrizia Giannoni

ACS Chemical Neuroscience, 2015, 6 (7), pp.940-943. ⟨10.1021/acschemneuro.5b00135⟩

Article dans une revue hal-01792388v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Cédric Lecoutey , Cédric Lecoutey , Florence Gaven , Patrizia Giannoni , Katia Hamidouche et al.

Journal of Medicinal Chemistry, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩

Article dans une revue hal-02043873v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey , Damien Hedou , Thomas Freret , Patrizia Giannoni , Florence Gaven et al.

Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩

Article dans une revue hal-01800439v2
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Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer’s disease

Patrizia Giannoni , Florence Gaven , Dimitri de Bundel , Kévin Baranger , Evelyne Marchetti-Gauthier et al.

Frontiers in Aging Neuroscience, 2013, 5, pp.96. ⟨10.3389/fnagi.2013.00096⟩

Article dans une revue hal-01703910v1
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Alzheimer culprits: cellular crossroads and interplay

Sylvie Claeysen , Maud Cochet-Bissuel , Romain Donneger , Aline Dumuis , Joël Bockaert et al.

Cellular Signalling, 2012, 24 (9), pp.1831-1840. ⟨10.1016/j.cellsig.2012.05.008⟩

Article dans une revue hal-01792371v1
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HISTAMINE NEURONAL SYSTEM AS THERAPEUTIC TARGET FOR THE TREATMENT OF COGNITIVE DISORDERS

Patrizio Blandina , Leonardo Munari , Patrizia Giannoni , Chiara Mariottini , Maria Beatrice Passani

Future Neurology, 2010, ⟨10.2217/fnl.10.30⟩

Article dans une revue hal-01793879v1
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Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat

Patrizia Giannoni , Maria-Beatrice Passani , Daniele Nosi , Paul L Chazot , Fiona C Shenton et al.

European Journal of Neuroscience, 2009

Article dans une revue hal-01756945v1

Regional Differential Effects of the Novel Histamine H3 Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats

Patrizia Giannoni , Andrew Medhurst , M. Passani , M. Giovannini , C. Ballini et al.

Journal of Pharmacology and Experimental Therapeutics, 2009, 332 (1), pp.164 - 172. ⟨10.1124/jpet.109.158444⟩

Article dans une revue hal-01764810v1

Histamine in the brain: Beyond sleep and memory

Maria Beatrice Passani , Corrado Bucherelli , Elisabetta Baldi , Patrizio Blandina , Patrizia Giannoni

Biochemical Pharmacology, 2007, 73 (8), pp.1113 - 1122. ⟨10.1016/j.bcp.2006.12.002⟩

Article dans une revue hal-01762502v1

Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain

Gabriele Cenni , Patrizio Blandina , Ken Mackie , Daniele Nosi , Lucia Formigli et al.

European Journal of Neuroscience, 2006, 24 (6), pp.1633 - 1644. ⟨10.1111/j.1460-9568.2006.05046.x⟩

Article dans une revue hal-01764807v1

Histamine Receptors_Chapter6_The Evolving Landscape of Histaminergic Neurons’ Heterogeneity: Functional and Therapeutic Implications

Patrizia Giannoni

Histamine receptors, Springer Nature Switzerland, 2025, The Receptors, 978-3-031-98920-9. ⟨10.1007/978-3-031-98921-6⟩

Chapitre d'ouvrage hal-05292373v1
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The 5×FAD mouse model of Alzheimer's disease

Sylvie Claeysen , Patrizia Giannoni , Caroline Ismeurt

The Neuroscience of Dementia, 1 (Chapter 13), Academic Press, pp.207-221, 2020, Diagnosis and Management in Dementia, 9780128158548. ⟨10.1016/B978-0-12-815854-8.00013-6⟩

Chapitre d'ouvrage hal-02920524v1

Heterogeneity of Histaminergic Neurons

Patrizia Giannoni

Patrizio Blandina; Maria Beatrice Passani. Histamine Receptors, Histamine Receptors (28), Humana Press, 2016, The Receptors, 978-3-319-40306-9. ⟨10.1007/978-3-319-40308-3_10⟩

Chapitre d'ouvrage hal-02147863v1
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Serotonin type 4 receptor dimers

Sylvie Claeysen , Romain Donneger , Patrizia Giannoni , Florence Gaven , Lucie P. Pellissier

Methods in Cell Biology - Receptor-Receptor Interactions, 117, Academic Press - Elsevier, pp.123-139, 2013, 117, 978-0-12-408143-7. ⟨10.1016/B978-0-12-408143-7.00007-4⟩

Chapitre d'ouvrage hal-01792387v1
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Zebrafish larvae exposed to BMAA and isomers DAB and AEG: a morphological and behavioural study

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni

SETAC EUROPE 34TH ANNUAL MEETING, Society of Environmental Toxicology and Chemistry, May 2024, Séville, Spain

Communication dans un congrès hal-04594098v1
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PRESCRIPTION DE BENZODIAZEPINES ET CONTAMINATION ENVIRONNEMENTALE -ANALYSE RETROSPECTIVE (2015-2022)

Jeanne Lichtfouse , Antoine Bonnière , Patrizia Giannoni , Eric Lichtfouse

SEFA-Société Française d’Ecotoxicologie Fondamentale et Appliquée, Jul 2024, Besançon, France

Communication dans un congrès hal-04920837v1

Unir la pédagogie active et les REL : développement des compétences, réussites personnelle et professionnelle

Patrizia Giannoni , Zohra Benfodda

Diversité, Réussite[s] dans l’Enseignement Supérieur (2024), Nantes Université [Nantes Univ], Apr 2024, Nantes, France

Communication dans un congrès hal-04560072v1

Artemia salina : les crevettes d'eau salée Occitane pour étudier la cyanotoxine BMAA et ses isomères, DAB et AEG.

Jeanne Lichtfouse , Lucas Lecluse , Anaëlle Demelier , Patrizia Giannoni

Enjeux et impacts de la pollution chimique et des déchets en Méditerranée, ECOBIM, May 2024, Banyuls - sur - Mer, France

Communication dans un congrès hal-04594271v1

EFFETS DE LA BMAA A DES CONCENTRATIONS ENVIRONNEMENTALES, SEULE OU EN MELANGE AVEC SES ISOMERES SUR LES LARVES DE POISSONS ZEBRES

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni

Colloque 2023 de la Société Française d’Ecotoxicologie Fondamentale et Appliquée, SEFA, Jul 2023, Le Havre, France

Communication dans un congrès hal-04157661v1

Environmental and Health Impact of Micropollutants in the Thau Lagoon

Audrey Courtier , Axelle Cadiere , Sandrine Bayle , Patrizia Giannoni , Benoit Roig

SCICON2 - SETAC North America 41st Annual Meeting, Nov 2020, Congrès virtuel, France

Communication dans un congrès hal-03094142v1

Caractérisation immunohistologique de la pathologie amyloïde et des symptômes associés dans un modèle murin dela maladie d'Alzheimer. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Sylvie Claeysen

AFH: association française d'histotechnologie, Jun 2015, Montpellier, France

Communication dans un congrès hal-02918582v1

Activation chronique du récepteur de la sérotonine de type 4 : Effet préventif dans un model murin de la maladied’Alzheimer. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

Réunion francophone sur la maladie d'Alzheimer, Jun 2014, Montpellier, France

Communication dans un congrès hal-02918585v1

Memory deficits of 5xFAD mice in the olfactory H maze test correlate with plaques development and are prevented by 5-HT4R agonist treatments.

Patrizia Giannoni , Kévin Baranger , Sarah Girot , Stéphane Girard , Florence Gaven et al.

AAIC, Jul 2014, Copenhague, Denmark

Communication dans un congrès hal-02918560v1

New insights in molecular aspects of Alzheimer’s disease. Conférencière invitée.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

Sindem, Mar 2013, Perugia, Italy

Communication dans un congrès hal-02918588v1

5-HT4 agonists: novel promising agents for AD prevention. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

36 th meeting of Societa’ Italiana di Farmacologia, 2013, Turin (Italie), October 23, Oct 2013, Turin, Italy

Communication dans un congrès hal-02918587v1

Prodromal stimulation of 5-HT4 receptors reduces amyloid pathology in 5XFAD mice.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

Club de neuroprotection, Nov 2012, Paris, France

Communication dans un congrès hal-02918562v1

Detection of functional heterogeneity of histaminergic neurons in response to GSK189254, a novel H3 antagonist.

Patrizia Giannoni , Maria Beatrice Passani , Daniele Nosi , Andrew Medhurst , Paul L Chazot et al.

36 th meeting of the European Histamine Research Society, May 2007, Florence, Italy

Communication dans un congrès hal-02918563v1

Different response to GABAa or H3 antagonists suggest the existence of distinct subpopulations among histaminergic neurons.

Patrizia Giannoni , Gabriele Cenni , Maria Beatrice Passani , Pier Francesco Mannaioni , Andrew Medhurst et al.

35 th meeting of the European Histamine Research Society, May 2006, Delphes, Greece

Communication dans un congrès hal-02918566v1
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MORPGHOLOGICAL AND BEHAVIOURAL ANALYSIS OF BMAA IN ZEBRAFISH LARVAE

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni

First French Zebrafish Meeting, Oct 2023, Montpellier, France

Poster de conférence hal-04263376v1
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BACTERIES ENVIRONNEMENTALES ET MALADIES DU CERVEAU

Patrizia Giannoni , Audrey Courtier , Damien Potheret , Jeanne Lichtfouse

Société d’Écotoxicologie Fondamentale et Appliquée (SEFA), Jul 2023, Le Havre, France

Poster de conférence hal-04136234v1
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Développement d'une méthode automatique de suivi de la croissance de Borrelia burgdorferi

Damien Potheret , Patrizia Giannoni , Axelle Cadiere

Microbes 2022 - 17e congrès national de la SFM, Oct 2022, Montpellier, France

Poster de conférence hal-04108122v1

Microbiote intestinal et maladie d’Alzheimer : une piste stratégique pour des biomarqueurs innovants ?

Patrizia Giannoni , Bérengère Coupé , Florence Gaven , Caroline Ismeurt , Kévin Baranger et al.

Biomarker days, Jun 2017, Montpellier, France

Poster de conférence hal-03131344v1

Impact du microbiote intestinal dans un modèle murin de maladie d’Alzheimer.

Patrizia Giannoni , Bérengère Coupé , Florence Gaven , Kévin Baranger , Santiago Rivera et al.

Réunion francophone sur la maladie d’Alzheimer et les syndromes apparentés, Jun 2016, Lyon, France

Poster de conférence hal-02917762v1

Time dependent vascular pericyte changes in a genetic model of Alzheimer’s disease.

Patrizia Giannoni , Margarita Arango-Lievano , Ines das Neves , Marie-Claude Rousset , Kévin Baranger et al.

CBV: Conference on Cerebral Vascular Biology, Jul 2015, Paris, France

Poster de conférence hal-02917765v1

Longitudinal cerebrovascular changes in a genetic model of Alzheimer’s disease.

Patrizia Giannoni , Yacine Belkacemi , Marie-Claude Rousset , Baddreddine Boussadia , Florence Gaven et al.

AD/PD, Mar 2015, Nice, France

Poster de conférence hal-02918542v1

5 HT4 agonists: novel promising agents for AD prevention.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

Congrès des Neurosciences Francaises, May 2013, Lyon, France

Poster de conférence hal-02918543v1

5 HT4 agonists: novel promising agents for AD prevention.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin et al.

AD/PD 2013, Mar 2013, Florence, Italy

Poster de conférence hal-02918547v1

Functional heterogeneity of histaminergic neurons suggest interesting applications of GSK189254, a novel H3 receptor antagonist

Patrizia Giannoni , Gabriele Cenni , Maria Beatrice Passani , Pier Francesco Mannaioni , Andrew Medhurst et al.

33 rd meeting of Societa’ Italiana di Farmacologia, Jun 2007, Cagliari, Italy

Poster de conférence hal-02918555v1