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Patrizia Giannoni

Patrizia Giannoni MCF Biologie, HDR, Chargée de mission "Aide à la réussite"
45
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  • 258776
Researcher identifiers
  • IdHAL patrizia-giannoni
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**EDUCATION** **2022 **HDR délivré par l'Université de Nîmes, France **2008 **Doctorat ès Pharmacologie et Toxicologie délivré par l'Université de Florence, Italie** **2004 **Doctorat ès Pharmacie *cum laude* délivré par l'Université de Florence, Italie** **PARCOURS PROFESSIONNEL** **2018- present **Maître de conférences;** Université de Nimes, Equipe Chrome (EA7352), Nimes, France **2016- 2018 **ATER en biologie;** Université de Nimes, Equipe Chrome (EA7352), Nimes, France **2011-2016 **Stage post-doctoral;** Institut de Génomique Fonctionnelle (IGF), Montpellier, France **2008-2011** **Stage post-doctoral;** New York University Medical center, New York, NY, USA **activités d’edition** **-Experte scientifique (reviewer)** pour: Molecules, Brain Sciences, Toxines, Journal of Clinical Medicine, Neuroscience, Journal of Neuroscience Research, Frontiers in Aging Neuroscience, International Journal of Molecular Sciences, Biomolecules, Psychopharmacology, Nutrients, Medicina, Pharmaceutics, Microorganisms, International Journal of Environmental Research and Public Health <https://publons.com/researcher/1234310/patrizia-giannoni/> **-Editeur invité** pour: · Frontiers in Aging Neuroscience (IF=5.750) <https://www.frontiersin.org/research-topics/8864/identification-of-multiple-targets-in-the-fight-against-alzheimers-disease> https://www.frontiersin.org/research-topics/19199/environmental-clues-to-brain-disease · Journal of Clinical Medicine (4.241) [https://www.mdpi.com/journal/jcm/special\_issues/alzheimer\_disease\_blueprints\_and\_therapeutic\_hints](https://www.mdpi.com/journal/jcm/special_issues/alzheimer_disease_blueprints_and_therapeutic_hints)). **-Membre du comité de rédaction** : · Frontiers in Bioscience Landmark (IF=4.009) <https://www.fbscience.com/Landmark/editorial-board>

Research domains

Bacteriology Cognitive Sciences Neurobiology Molecular biology Global Changes Neuroscience

Skills

Publications

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Editorial: Environmental clues to brain disease

Patrizia Giannoni , Federica Bertaso , Gustavo Provensi
Frontiers in Aging Neuroscience, 2023, 15, pp.1220484. ⟨10.3389/fnagi.2023.1220484⟩
Journal articles hal-04136217v1

Environmental bacteria as triggers to brain disease: Possible mechanisms of toxicity and associated human risk

Audrey Courtier , Damien Potheret , Patrizia Giannoni
Life Sciences, 2022, 304, pp.120689. ⟨10.1016/j.lfs.2022.120689⟩
Journal articles hal-04064228v1
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Peripheral Routes to Neurodegeneration: Passing Through the Blood–Brain Barrier

Patrizia Giannoni , Sylvie Claeysen , Francesco Noe , Nicola Marchi
Frontiers in Aging Neuroscience, 2020, 12, pp.3. ⟨10.3389/fnagi.2020.00003⟩
Journal articles hal-02465771v1
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Development of a DGGE method to explore Legionella communities

Sandrine Bayle , B Martinez-Arribas , S. Jarraud , Patrizia Giannoni , L Garrelly
Heliyon, 2020, 6 (1), pp.e03149. ⟨10.1016/j.heliyon.2019.e03149⟩
Journal articles hal-02430628v1
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Editorial: Identification of Multiple Targets in the Fight Against Alzheimer's Disease

Patrizia Giannoni , Silvia Fossati , Elena Marcello , Sylvie Claeysen
Frontiers in Aging Neuroscience, 2020, 1, ⟨10.3389/fnagi.2020.00169⟩
Journal articles hal-02871844v1
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Donecopride, a Swiss army knife with potential interest against Alzheimer's disease

Christophe Rochais , Cédric Lecoutey , Katia Hamidouche , Patrizia Giannoni , Florence Gaven
British Journal of Pharmacology, inPress, 177 (9), pp.1988-2005. ⟨10.1111/bph.14964⟩
Journal articles hal-02428730v1
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The pericyte–glia interface at the blood–brain barrier

Patrizia Giannoni , Jerome Badaut , Cyril Dargazanli , Alexis Fayd'Herbe de Maudave , Wendy Klement
Clinical Science, 2018, 132 (3), pp.361-374. ⟨10.1042/CS20171634⟩
Journal articles hal-02074159v1
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Chronic treatments with a 5-HT4 receptor agonist decrease amyloid pathology in the entorhinal cortex and learning and memory deficits in the 5xFAD mouse model of Alzheimer's disease

Kévin Baranger , Patrizia Giannoni , Stéphane Girard , Sarah Girot , Florence Gaven
Neuropharmacology, 2017, 126, pp.128-141. ⟨10.1016/j.neuropharm.2017.08.031⟩
Journal articles hal-01799428v1
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Longitudinal in vivo Imaging of the Cerebrovasculature: Relevance to CNS Diseases

Margarita Arango-Lievano , Patrizia Giannoni , Sylvie Claeysen , Nicola Marchi , Freddy Jeanneteau
Journal of visualized experiments : JoVE, 2016, ⟨10.3791/54796⟩
Journal articles hal-02368047v1
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The carbonic anhydrase inhibitor methazolamide prevents amyloid beta-induced mitochondrial dysfunction and caspase activation protecting neuronal and glial cells in vitro and in the mouse brain

Silvia Fossati , Patrizia Giannoni , Maria E Solesio , Sarah L Cocklin , Erwin Cabrera
Neurobiology of Disease, 2016, 86, pp.29-40. ⟨10.1016/j.nbd.2015.11.006⟩
Journal articles hal-01997866v1
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Cerebrovascular pathology during the progression of experimental Alzheimer's disease

Patrizia Giannoni , Margarita Arango-Lievano , Ines das Neves , Marie-Claude Rousset , Kévin Baranger
Neurobiology of Disease, 2016, 88, pp.107-117. ⟨10.1016/j.nbd.2016.01.001⟩
Journal articles hal-01477817v1

In vivo Differential Brain Clearance and Catabolism of Monomeric and Oligomeric Alzheimer's Aβ protein

Farron Mcintee , Patrizia Giannoni , Steven Blais , George Sommer , Thomas Neubert
Frontiers in Aging Neuroscience, 2016, 8, ⟨10.3389/fnagi.2016.00223⟩
Journal articles hal-01705732v1
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Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT 4 R) Agonist Activities As Potential Agents against Alzheimer’s Disease: The Design of Donecopride

Cédric Lecoutey , Cédric Lecoutey , Florence Gaven , Patrizia Giannoni , Katia Hamidouche
Journal of Medicinal Chemistry, 2015, 58 (7), pp.3172-3187. ⟨10.1021/acs.jmedchem.5b00115⟩
Journal articles hal-02043873v1
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Serotonin: a new hope in Alzheimer's disease?

Sylvie Claeysen , Joël Bockaert , Patrizia Giannoni
ACS Chemical Neuroscience, 2015, 6 (7), pp.940-943. ⟨10.1021/acschemneuro.5b00135⟩
Journal articles hal-01792388v1
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Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment

Cédric Lecoutey , Damien Hedou , Thomas Freret , Patrizia Giannoni , Florence Gaven
Proceedings of the National Academy of Sciences of the United States of America, 2014, 111 (36), pp.E3825--30. ⟨10.1073/pnas.1410315111⟩
Journal articles hal-01800439v2
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Early administration of RS 67333, a specific 5-HT4 receptor agonist, prevents amyloidogenesis and behavioral deficits in the 5XFAD mouse model of Alzheimer’s disease

Patrizia Giannoni , Florence Gaven , Dimitri de Bundel , Kévin Baranger , Evelyne Marchetti-Gauthier
Frontiers in Aging Neuroscience, 2013, 5, pp.96. ⟨10.3389/fnagi.2013.00096⟩
Journal articles hal-01703910v1
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Alzheimer culprits: cellular crossroads and interplay

Sylvie Claeysen , Maud Cochet-Bissuel , Romain Donneger , Aline Dumuis , Joël Bockaert
Cellular Signalling, 2012, 24 (9), pp.1831-1840. ⟨10.1016/j.cellsig.2012.05.008⟩
Journal articles hal-01792371v1
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HISTAMINE NEURONAL SYSTEM AS THERAPEUTIC TARGET FOR THE TREATMENT OF COGNITIVE DISORDERS

Patrizio Blandina , Leonardo Munari , Patrizia Giannoni , Chiara Mariottini , Maria Beatrice Passani
Future Neurology, 2010, ⟨10.2217/fnl.10.30⟩
Journal articles hal-01793879v1

Regional Differential Effects of the Novel Histamine H3 Receptor Antagonist 6-[(3-Cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepin-7-yl)oxy]-N-methyl-3-pyridinecarboxamide hydrochloride (GSK189254) on Histamine Release in the Central Nervous System of Freely Moving Rats

Patrizia Giannoni , Andrew Medhurst , M. Passani , M. Giovannini , C. Ballini
Journal of Pharmacology and Experimental Therapeutics, 2009, 332 (1), pp.164 - 172. ⟨10.1124/jpet.109.158444⟩
Journal articles hal-01764810v1
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Heterogeneity of histaminergic neurons in the tuberomammillary nucleus of the rat

Patrizia Giannoni , Maria-Beatrice Passani , Daniele Nosi , Paul L Chazot , Fiona C Shenton
European Journal of Neuroscience, 2009
Journal articles hal-01756945v1

Histamine in the brain: Beyond sleep and memory

Maria Beatrice Passani , Corrado Bucherelli , Elisabetta Baldi , Patrizio Blandina , Patrizia Giannoni
Biochemical Pharmacology, 2007, 73 (8), pp.1113 - 1122. ⟨10.1016/j.bcp.2006.12.002⟩
Journal articles hal-01762502v1

Differential effect of cannabinoid agonists and endocannabinoids on histamine release from distinct regions of the rat brain

Gabriele Cenni , Patrizio Blandina , Ken Mackie , Daniele Nosi , Lucia Formigli
European Journal of Neuroscience, 2006, 24 (6), pp.1633 - 1644. ⟨10.1111/j.1460-9568.2006.05046.x⟩
Journal articles hal-01764807v1
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The 5×FAD mouse model of Alzheimer's disease

Sylvie Claeysen , Patrizia Giannoni , Caroline Ismeurt
The Neuroscience of Dementia, 1 (Chapter 13), Academic Press, pp.207-221, 2020, Diagnosis and Management in Dementia, 9780128158548. ⟨10.1016/B978-0-12-815854-8.00013-6⟩
Book sections hal-02920524v1

Heterogeneity of Histaminergic Neurons

Patrizia Giannoni
Patrizio Blandina; Maria Beatrice Passani. Histamine Receptors, Histamine Receptors (28), Humana Press, 2016, The Receptors, 978-3-319-40306-9. ⟨10.1007/978-3-319-40308-3_10⟩
Book sections hal-02147863v1
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Serotonin type 4 receptor dimers

Sylvie Claeysen , Romain Donneger , Patrizia Giannoni , Florence Gaven , Lucie P. Pellissier
Methods in Cell Biology - Receptor-Receptor Interactions, 117, Academic Press - Elsevier, pp.123-139, 2013, 117, 978-0-12-408143-7. ⟨10.1016/B978-0-12-408143-7.00007-4⟩
Book sections hal-01792387v1

EFFETS DE LA BMAA A DES CONCENTRATIONS ENVIRONNEMENTALES, SEULE OU EN MELANGE AVEC SES ISOMERES SUR LES LARVES DE POISSONS ZEBRES

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni
Colloque 2023 de la Société Française d’Ecotoxicologie Fondamentale et Appliquée, SEFA, Jul 2023, Le Havre, France
Conference papers hal-04157661v1

Environmental and Health Impact of Micropollutants in the Thau Lagoon

Audrey Courtier , Axelle Cadiere , Sandrine Bayle , Patrizia Giannoni , Benoit Roig
SCICON2 - SETAC North America 41st Annual Meeting, Nov 2020, Congrès virtuel, France
Conference papers hal-03094142v1

Caractérisation immunohistologique de la pathologie amyloïde et des symptômes associés dans un modèle murin dela maladie d'Alzheimer. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Sylvie Claeysen
AFH: association française d'histotechnologie, Jun 2015, Montpellier, France
Conference papers hal-02918582v1

Activation chronique du récepteur de la sérotonine de type 4 : Effet préventif dans un model murin de la maladied’Alzheimer. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
Réunion francophone sur la maladie d'Alzheimer, Jun 2014, Montpellier, France
Conference papers hal-02918585v1

Memory deficits of 5xFAD mice in the olfactory H maze test correlate with plaques development and are prevented by 5-HT4R agonist treatments.

Patrizia Giannoni , Kévin Baranger , Sarah Girot , Stéphane Girard , Florence Gaven
AAIC, Jul 2014, Copenhague, Denmark
Conference papers hal-02918560v1

New insights in molecular aspects of Alzheimer’s disease. Conférencière invitée.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
Sindem, Mar 2013, Perugia, Italy
Conference papers hal-02918588v1

5-HT4 agonists: novel promising agents for AD prevention. (Conférencière invitée)

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
36 th meeting of Societa’ Italiana di Farmacologia, 2013, Turin (Italie), October 23, Oct 2013, Turin, Italy
Conference papers hal-02918587v1

Prodromal stimulation of 5-HT4 receptors reduces amyloid pathology in 5XFAD mice.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
Club de neuroprotection, Nov 2012, Paris, France
Conference papers hal-02918562v1

Detection of functional heterogeneity of histaminergic neurons in response to GSK189254, a novel H3 antagonist.

Patrizia Giannoni , Maria Beatrice Passani , Daniele Nosi , Andrew Medhurst , Paul L Chazot
36 th meeting of the European Histamine Research Society, May 2007, Florence, Italy
Conference papers hal-02918563v1

Different response to GABAa or H3 antagonists suggest the existence of distinct subpopulations among histaminergic neurons.

Patrizia Giannoni , Gabriele Cenni , Maria Beatrice Passani , Pier Francesco Mannaioni , Andrew Medhurst
35 th meeting of the European Histamine Research Society, May 2006, Delphes, Greece
Conference papers hal-02918566v1
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MORPGHOLOGICAL AND BEHAVIOURAL ANALYSIS OF BMAA IN ZEBRAFISH LARVAE

Jeanne Lichtfouse , Audrey Courtier , Annette C Vergunst , Patrizia Giannoni
First French Zebrafish Meeting, Oct 2023, Montpellier, France
Conference poster hal-04263376v1
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BACTERIES ENVIRONNEMENTALES ET MALADIES DU CERVEAU

Patrizia Giannoni , Audrey Courtier , Damien Potheret , Jeanne Lichtfouse
Société d’Écotoxicologie Fondamentale et Appliquée (SEFA), Jul 2023, Le Havre, France
Conference poster hal-04136234v1
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Développement d'une méthode automatique de suivi de la croissance de Borrelia burgdorferi

Damien Potheret , Patrizia Giannoni , Axelle Cadiere
Microbes 2022 - 17e congrès national de la SFM, Oct 2022, Montpellier, France
Conference poster hal-04108122v1

Microbiote intestinal et maladie d’Alzheimer : une piste stratégique pour des biomarqueurs innovants ?

Patrizia Giannoni , Bérengère Coupé , Florence Gaven , Caroline Ismeurt , Kévin Baranger
Biomarker days, Jun 2017, Montpellier, France
Conference poster hal-03131344v1

Impact du microbiote intestinal dans un modèle murin de maladie d’Alzheimer.

Patrizia Giannoni , Bérengère Coupé , Florence Gaven , Kévin Baranger , Santiago Rivera
Réunion francophone sur la maladie d’Alzheimer et les syndromes apparentés, Jun 2016, Lyon, France
Conference poster hal-02917762v1

Time dependent vascular pericyte changes in a genetic model of Alzheimer’s disease.

Patrizia Giannoni , Margarita Arango-Lievano , Ines das Neves , Marie-Claude Rousset , Kévin Baranger
CBV: Conference on Cerebral Vascular Biology, Jul 2015, Paris, France
Conference poster hal-02917765v1

Longitudinal cerebrovascular changes in a genetic model of Alzheimer’s disease.

Patrizia Giannoni , Yacine Belkacemi , Marie-Claude Rousset , Baddreddine Boussadia , Florence Gaven
AD/PD, Mar 2015, Nice, France
Conference poster hal-02918542v1

5 HT4 agonists: novel promising agents for AD prevention.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
AD/PD 2013, Mar 2013, Florence, Italy
Conference poster hal-02918547v1

5 HT4 agonists: novel promising agents for AD prevention.

Patrizia Giannoni , Florence Gaven , Kévin Baranger , Santiago Rivera , Philippe Marin
Congrès des Neurosciences Francaises, May 2013, Lyon, France
Conference poster hal-02918543v1

Functional heterogeneity of histaminergic neurons suggest interesting applications of GSK189254, a novel H3 receptor antagonist

Patrizia Giannoni , Gabriele Cenni , Maria Beatrice Passani , Pier Francesco Mannaioni , Andrew Medhurst
33 rd meeting of Societa’ Italiana di Farmacologia, Jun 2007, Cagliari, Italy
Conference poster hal-02918555v1